[
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Determine whether ENSG00000169410 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Determine whether PTPN9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2356
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor ENSG00000168209 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000168209 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor DDIT4 expression. Decide whether this perturbation leads to a significant alteration in DDIT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":738
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2190
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of ENSG00000119535. Does perturbing CITED1 lead to a significant change in ENSG00000119535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of CSF3R. Does perturbing CITED1 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":581
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1009
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ENSG00000163513. Does perturbing TGFBR2 lead to a significant change in ENSG00000163513 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of TGFBR2. Does perturbing TGFBR2 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2821
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and ENSG00000237330 expression is observed. Does this perturbation lead to a significant difference in ENSG00000237330 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and RNF223 expression is observed. Does this perturbation lead to a significant difference in RNF223 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2403
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and ENSG00000092067 expression is measured. Determine whether ENSG00000092067 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CEBPE expression is measured. Determine whether CEBPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":529
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":272
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1130
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and ENSG00000090382 expression is observed. Does this perturbation lead to a significant difference in ENSG00000090382 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and LYZ expression is observed. Does this perturbation lead to a significant difference in LYZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1043
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ENSG00000143401 expression is quantified. Does this perturbation result in a significant change in ENSG00000143401 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ANP32E expression is quantified. Does this perturbation result in a significant change in ANP32E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2082
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of ENSG00000130656. Does perturbing SAMD1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HBZ. Does perturbing SAMD1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2501
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2383
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ENSG00000157557 expression is quantified. Does this perturbation result in a significant change in ENSG00000157557 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ETS2 expression is quantified. Does this perturbation result in a significant change in ETS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":952
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000117091 is measured. Does this perturbation cause a significant change in ENSG00000117091 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of CD48 is measured. Does this perturbation cause a significant change in CD48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1370
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1254
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Does this perturbation cause a significant change in ENSG00000092067 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Does this perturbation cause a significant change in CEBPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":510
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":696
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":408
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Determine whether ENSG00000170689 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Determine whether HOXB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1326
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ENSG00000170542. Does this perturbation cause a significant change in ENSG00000170542 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of SERPINB9. Does this perturbation cause a significant change in SERPINB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2534
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and ENSG00000279529 expression is measured. Determine whether ENSG00000279529 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and CTD-3222D19.8 expression is measured. Determine whether CTD-3222D19.8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1649
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ENSG00000118515. Does perturbing SGK1 lead to a significant change in ENSG00000118515 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of SGK1. Does perturbing SGK1 lead to a significant change in SGK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2551
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":889
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of ENSG00000101076 is measured. Determine whether ENSG00000101076 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of HNF4A is measured. Determine whether HNF4A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1266
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and ENSG00000163531 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163531 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and NFASC expression is observed. Does this perturbation lead to a significant difference in NFASC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1763
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ENSG00000142669 expression is measured. Determine whether ENSG00000142669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and SH3BGRL3 expression is measured. Determine whether SH3BGRL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1019
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENSG00000186051 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in TAL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2335
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2070
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and ENSG00000115844 expression is quantified. Does this perturbation result in a significant change in ENSG00000115844 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and DLX2 expression is quantified. Does this perturbation result in a significant change in DLX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":812
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of ENSG00000108821. Does this perturbation cause a significant change in ENSG00000108821 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of COL1A1. Does this perturbation cause a significant change in COL1A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":724
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and ENSG00000184481 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184481 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and FOXO4 expression is observed. Does this perturbation lead to a significant difference in FOXO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1143
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ENSG00000128016 is measured. Does this perturbation cause a significant change in ENSG00000128016 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ZFP36 is measured. Does this perturbation cause a significant change in ZFP36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2050
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":890
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of ENSG00000172331 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of BPGM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":217
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ENSG00000157557. Does perturbing ETS2 lead to a significant change in ENSG00000157557 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ETS2. Does perturbing ETS2 lead to a significant change in ETS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":931
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of ENSG00000163499. Does perturbing FEV lead to a significant change in ENSG00000163499 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of CRYBA2. Does perturbing FEV lead to a significant change in CRYBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":961
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of ENSG00000153094 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of BCL2L11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":157
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor ENSG00000118058 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000118058 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor KMT2A expression. Decide whether this perturbation leads to a significant alteration in KMT2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1688
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2578
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1259
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ENSG00000090382 expression is observed. Does this perturbation lead to a significant difference in ENSG00000090382 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LYZ expression is observed. Does this perturbation lead to a significant difference in LYZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1053
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ENSG00000090382 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000090382 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LYZ expression. Decide whether this perturbation leads to a significant alteration in LYZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1058
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2599
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ENSG00000105610. Does this perturbation cause a significant change in ENSG00000105610 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of KLF1. Does this perturbation cause a significant change in KLF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1674
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of ENSG00000153012. Does this perturbation cause a significant change in ENSG00000153012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of LGI2. Does this perturbation cause a significant change in LGI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":484
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor ENSG00000164920 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000164920 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor OSR2 expression. Decide whether this perturbation leads to a significant alteration in OSR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2118
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1529
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000104894 is measured. Determine whether ENSG00000104894 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of CD37 is measured. Determine whether CD37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":776
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of ENSG00000277268. Does perturbing LHX1 lead to a significant change in ENSG00000277268 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of RP11-445F12.1. Does perturbing LHX1 lead to a significant change in RP11-445F12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1721
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of ENSG00000198758 is measured. Determine whether ENSG00000198758 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of EPS8L3 is measured. Determine whether EPS8L3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1286
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2075
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ENSG00000118515 expression is observed. Does this perturbation lead to a significant difference in ENSG00000118515 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and SGK1 expression is observed. Does this perturbation lead to a significant difference in SGK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2553
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ENSG00000076356. Does perturbing MAML2 lead to a significant change in ENSG00000076356 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of PLXNA2. Does perturbing MAML2 lead to a significant change in PLXNA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1781
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000196565 is measured. Determine whether ENSG00000196565 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of HBG2 is measured. Determine whether HBG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2396
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ENSG00000110492. Does this perturbation cause a significant change in ENSG00000110492 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of MDK. Does this perturbation cause a significant change in MDK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2204
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":424
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and ENSG00000166340 expression is quantified. Does this perturbation result in a significant change in ENSG00000166340 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and TPP1 expression is quantified. Does this perturbation result in a significant change in TPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1152
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Does this perturbation cause a significant change in ENSG00000184697 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Does this perturbation cause a significant change in CLDN6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":630
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and ENSG00000184481 expression is quantified. Does this perturbation result in a significant change in ENSG00000184481 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and FOXO4 expression is quantified. Does this perturbation result in a significant change in FOXO4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1142
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ENSG00000143401 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143401 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ANP32E expression is observed. Does this perturbation lead to a significant difference in ANP32E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2083
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of ENSG00000105223 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of PLD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1227
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ENSG00000137841 expression is measured. Determine whether ENSG00000137841 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and PLCB2 expression is measured. Determine whether PLCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2139
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of ENSG00000184481 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of FOXO4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1147
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ENSG00000206172 expression is observed. Does this perturbation lead to a significant difference in ENSG00000206172 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and HBA1 expression is observed. Does this perturbation lead to a significant difference in HBA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2273
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of ENSG00000090382. Does this perturbation cause a significant change in ENSG00000090382 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of LYZ. Does this perturbation cause a significant change in LYZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1044
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of ENSG00000250361. Does perturbing BCL2L11 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of GYPB. Does perturbing BCL2L11 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":161
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ENSG00000090382 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LYZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1055
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of ENSG00000135409. Does perturbing BPGM lead to a significant change in ENSG00000135409 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of AMHR2. Does perturbing BPGM lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":221
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ENSG00000184384. Does this perturbation cause a significant change in ENSG00000184384 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of MAML2. Does this perturbation cause a significant change in MAML2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1774
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000090382 is measured. Determine whether ENSG00000090382 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of LYZ is measured. Determine whether LYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1046
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1873
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and ENSG00000163499 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163499 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and CRYBA2 expression is observed. Does this perturbation lead to a significant difference in CRYBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":963
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2216
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":344
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ENSG00000100097 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":805
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor ENSG00000247516 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000247516 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor MIR4458HG expression. Decide whether this perturbation leads to a significant alteration in MIR4458HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3088
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of ENSG00000169410 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PTPN9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2357
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of ENSG00000158517 is measured. Determine whether ENSG00000158517 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of NCF1 is measured. Determine whether NCF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":476
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and ENSG00000163497 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163497 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":973
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ENSG00000144655 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in CSRNP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":785
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ENSG00000141753 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of IGFBP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":397
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2508
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ENSG00000079102 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in RUNX1T1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2445
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in ENSG00000164687 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1695
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of ENSG00000169410. Does this perturbation cause a significant change in ENSG00000169410 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PTPN9. Does this perturbation cause a significant change in PTPN9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2354
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of ENSG00000125931. Does this perturbation cause a significant change in ENSG00000125931 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of CITED1. Does this perturbation cause a significant change in CITED1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":574
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ENSG00000143401 expression is measured. Determine whether ENSG00000143401 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ANP32E expression is measured. Determine whether ANP32E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2089
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ENSG00000005187 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":907
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ENSG00000104894 expression is quantified. Does this perturbation result in a significant change in ENSG00000104894 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and CD37 expression is quantified. Does this perturbation result in a significant change in CD37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":772
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ENSG00000184697. Does perturbing CLDN6 lead to a significant change in ENSG00000184697 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CLDN6. Does perturbing CLDN6 lead to a significant change in CLDN6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":631
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ENSG00000174498. Does perturbing IGDCC3 lead to a significant change in ENSG00000174498 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of IGDCC3. Does perturbing IGDCC3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1421
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Does this perturbation cause a significant change in ENSG00000174498 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1410
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ENSG00000144655 expression is quantified. Does this perturbation result in a significant change in ENSG00000144655 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and CSRNP1 expression is quantified. Does this perturbation result in a significant change in CSRNP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":782
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of ENSG00000121900. Does perturbing TBX2 lead to a significant change in ENSG00000121900 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of TMEM54. Does perturbing TBX2 lead to a significant change in TMEM54 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2761
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1467
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENSG00000182871 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of COL18A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2327
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ENSG00000159556 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ISL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1507
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ENSG00000186185 is measured. Determine whether ENSG00000186185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of KIF18B is measured. Determine whether KIF18B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1606
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of ENSG00000111057 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of KRT18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":197
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of ENSG00000105697. Does this perturbation cause a significant change in ENSG00000105697 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of HAMP. Does this perturbation cause a significant change in HAMP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2484
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":343
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of ENSG00000203989. Does this perturbation cause a significant change in ENSG00000203989 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of RHOXF2BB. Does this perturbation cause a significant change in RHOXF2BB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2754
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000090238 is measured. Determine whether ENSG00000090238 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of YPEL3 is measured. Determine whether YPEL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1166
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of ENSG00000090238. Does perturbing FOXO4 lead to a significant change in ENSG00000090238 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of YPEL3. Does perturbing FOXO4 lead to a significant change in YPEL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1161
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ENSG00000166450 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of PRTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2237
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ENSG00000183770 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":295
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of ENSG00000068078 is measured. Does this perturbation cause a significant change in ENSG00000068078 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of FGFR3 is measured. Does this perturbation cause a significant change in FGFR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Determine whether ENSG00000116871 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1926
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000117139 is measured. Does this perturbation cause a significant change in ENSG00000117139 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of KDM5B is measured. Does this perturbation cause a significant change in KDM5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3140
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2505
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ENSG00000119969 expression is quantified. Does this perturbation result in a significant change in ENSG00000119969 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and HELLS expression is quantified. Does this perturbation result in a significant change in HELLS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2152
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ENSG00000109099 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of PMP22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1197
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ENSG00000119969 is measured. Determine whether ENSG00000119969 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of HELLS is measured. Determine whether HELLS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2156
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1469
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ENSG00000133317 expression is measured. Determine whether ENSG00000133317 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and LGALS12 expression is measured. Determine whether LGALS12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2459
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ENSG00000187997 expression is observed. Does this perturbation lead to a significant difference in ENSG00000187997 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and C17orf99 expression is observed. Does this perturbation lead to a significant difference in C17orf99 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":433
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ENSG00000139219 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of COL2A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":767
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ENSG00000108984 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000108984 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor MAP2K6 expression. Decide whether this perturbation leads to a significant alteration in MAP2K6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1848
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1017
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000070214 is measured. Does this perturbation cause a significant change in ENSG00000070214 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of SLC44A1 is measured. Does this perturbation cause a significant change in SLC44A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1170
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ENSG00000170180. Does this perturbation cause a significant change in ENSG00000170180 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of GYPA. Does this perturbation cause a significant change in GYPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":714
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2425
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ENSG00000170689 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of HOXB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1337
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in ENSG00000206172 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in HBA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2465
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ENSG00000258274 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in RP11-887P2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1315
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and ENSG00000129514 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129514 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FOXA1 expression is observed. Does this perturbation lead to a significant difference in FOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1033
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ENSG00000196565. Does this perturbation cause a significant change in ENSG00000196565 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of HBG2. Does this perturbation cause a significant change in HBG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2394
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Determine whether ENSG00000163499 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Determine whether CRYBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":986
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000256713 is measured. Does this perturbation cause a significant change in ENSG00000256713 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PGA5 is measured. Does this perturbation cause a significant change in PGA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":700
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ENSG00000258274 expression is measured. Determine whether ENSG00000258274 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and RP11-887P2.5 expression is measured. Determine whether RP11-887P2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1319
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of ENSG00000101076 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of HNF4A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1267
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1906
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2006
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of ENSG00000279529 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of CTD-3222D19.8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1647
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ENSG00000266976 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000266976 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor AC079466.1 expression. Decide whether this perturbation leads to a significant alteration in AC079466.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1858
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ENSG00000109099 expression is measured. Determine whether ENSG00000109099 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and PMP22 expression is measured. Determine whether PMP22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1199
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2693
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ENSG00000105610 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105610 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor KLF1 expression. Decide whether this perturbation leads to a significant alteration in KLF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1678
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in ENSG00000243449 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in C4orf48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":545
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ENSG00000170542 expression is measured. Determine whether ENSG00000170542 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and SERPINB9 expression is measured. Determine whether SERPINB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2539
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of ENSG00000243449. Does this perturbation cause a significant change in ENSG00000243449 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of C4orf48. Does this perturbation cause a significant change in C4orf48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":544
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ENSG00000187997 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of C17orf99 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":437
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ENSG00000133317 expression is observed. Does this perturbation lead to a significant difference in ENSG00000133317 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and LGALS12 expression is observed. Does this perturbation lead to a significant difference in LGALS12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2453
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and ENSG00000135111 expression is quantified. Does this perturbation result in a significant change in ENSG00000135111 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and TBX3 expression is quantified. Does this perturbation result in a significant change in TBX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2812
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ENSG00000169413 expression is quantified. Does this perturbation result in a significant change in ENSG00000169413 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and RNASE6 expression is quantified. Does this perturbation result in a significant change in RNASE6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1912
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ENSG00000011600 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2725
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ENSG00000102804 expression is measured. Determine whether ENSG00000102804 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and TSC22D1 expression is measured. Determine whether TSC22D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":289
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Determine whether ENSG00000101200 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2806
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1669
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is quantified. Does this perturbation result in a significant change in ENSG00000169410 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PTPN9 expression is quantified. Does this perturbation result in a significant change in PTPN9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2342
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ENSG00000135047 expression is quantified. Does this perturbation result in a significant change in ENSG00000135047 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3102
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ENSG00000234965 expression is measured. Determine whether ENSG00000234965 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and SHISA8 expression is measured. Determine whether SHISA8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2529
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is quantified. Does this perturbation result in a significant change in ENSG00000258274 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is quantified. Does this perturbation result in a significant change in RP11-887P2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1362
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor ENSG00000255346 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000255346 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor NOX5 expression. Decide whether this perturbation leads to a significant alteration in NOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2898
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in ENSG00000265972 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1245
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of ENSG00000121900. Does this perturbation cause a significant change in ENSG00000121900 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of TMEM54. Does this perturbation cause a significant change in TMEM54 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2774
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2714
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of ENSG00000121068. Does this perturbation cause a significant change in ENSG00000121068 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of TBX2. Does this perturbation cause a significant change in TBX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2784
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and ENSG00000245848 expression is observed. Does this perturbation lead to a significant difference in ENSG00000245848 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and CEBPA expression is observed. Does this perturbation lead to a significant difference in CEBPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":553
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ENSG00000135047. Does this perturbation cause a significant change in ENSG00000135047 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2604
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ENSG00000196565 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196565 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor HBG2 expression. Decide whether this perturbation leads to a significant alteration in HBG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":308
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and ENSG00000163497 expression is measured. Determine whether ENSG00000163497 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":979
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2697
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ENSG00000197766. Does this perturbation cause a significant change in ENSG00000197766 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of CFD. Does this perturbation cause a significant change in CFD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2064
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ENSG00000108984. Does this perturbation cause a significant change in ENSG00000108984 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of MAP2K6. Does this perturbation cause a significant change in MAP2K6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1844
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of ENSG00000119535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":467
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ENSG00000159556 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159556 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ISL2 expression is observed. Does this perturbation lead to a significant difference in ISL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1503
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2182
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ENSG00000169442 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169442 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1953
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ENSG00000204472. Does this perturbation cause a significant change in ENSG00000204472 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":944
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in ENSG00000121900 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in TMEM54 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2765
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ENSG00000140287. Does this perturbation cause a significant change in ENSG00000140287 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of HDC. Does this perturbation cause a significant change in HDC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2174
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of ENSG00000129514. Does this perturbation cause a significant change in ENSG00000129514 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FOXA1. Does this perturbation cause a significant change in FOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1024
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ENSG00000188483. Does this perturbation cause a significant change in ENSG00000188483 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of IER5L. Does this perturbation cause a significant change in IER5L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1384
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2415
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Does this perturbation cause a significant change in ENSG00000124762 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Does this perturbation cause a significant change in CDKN1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":370
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1514
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1659
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1988
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ENSG00000119969 is measured. Does this perturbation cause a significant change in ENSG00000119969 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of HELLS is measured. Does this perturbation cause a significant change in HELLS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2150
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Determine whether ENSG00000101200 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2796
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and ENSG00000273706 expression is quantified. Does this perturbation result in a significant change in ENSG00000273706 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2197
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2377
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1955
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000168209 is measured. Does this perturbation cause a significant change in ENSG00000168209 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of DDIT4 is measured. Does this perturbation cause a significant change in DDIT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":730
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ENSG00000130829 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130829 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and DUSP9 expression is observed. Does this perturbation lead to a significant difference in DUSP9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":843
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000106031 is measured. Determine whether ENSG00000106031 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of HOXA13 is measured. Determine whether HOXA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1296
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ENSG00000149516 expression is observed. Does this perturbation lead to a significant difference in ENSG00000149516 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and MS4A3 expression is observed. Does this perturbation lead to a significant difference in MS4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":993
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of ENSG00000090238 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of YPEL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1167
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and ENSG00000158517 expression is quantified. Does this perturbation result in a significant change in ENSG00000158517 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and NCF1 expression is quantified. Does this perturbation result in a significant change in NCF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":472
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ENSG00000183770. Does this perturbation cause a significant change in ENSG00000183770 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1114
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in ENSG00000163497 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1735
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1900
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ENSG00000135047. Does this perturbation cause a significant change in ENSG00000135047 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1884
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":794
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2517
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2512
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ENSG00000140287 expression is observed. Does this perturbation lead to a significant difference in ENSG00000140287 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and HDC expression is observed. Does this perturbation lead to a significant difference in HDC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2173
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2213
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ENSG00000141753 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in IGFBP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":395
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and ENSG00000092067 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092067 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CEBPE expression is observed. Does this perturbation lead to a significant difference in CEBPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":513
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor ENSG00000092067 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092067 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CEBPE expression. Decide whether this perturbation leads to a significant alteration in CEBPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":518
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2260
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of ENSG00000179111 is measured. Does this perturbation cause a significant change in ENSG00000179111 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of HES7 is measured. Does this perturbation cause a significant change in HES7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1200
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ENSG00000170608. Does perturbing FOXA3 lead to a significant change in ENSG00000170608 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of FOXA3. Does perturbing FOXA3 lead to a significant change in FOXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1061
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of ENSG00000141753. Does this perturbation cause a significant change in ENSG00000141753 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of IGFBP4. Does this perturbation cause a significant change in IGFBP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2964
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is quantified. Does this perturbation result in a significant change in ENSG00000258274 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is quantified. Does this perturbation result in a significant change in RP11-887P2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1352
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ENSG00000149516 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in MS4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":995
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2386
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of ENSG00000071967 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of CYBRD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1497
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ENSG00000206172. Does this perturbation cause a significant change in ENSG00000206172 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HBA1. Does this perturbation cause a significant change in HBA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1454
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in ENSG00000198758 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in EPS8L3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1285
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Does this perturbation cause a significant change in ENSG00000154127 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2970
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of ENSG00000240065. Does perturbing IRF1 lead to a significant change in ENSG00000240065 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of PSMB9. Does perturbing IRF1 lead to a significant change in PSMB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1481
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of ENSG00000071967 is measured. Does this perturbation cause a significant change in ENSG00000071967 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of CYBRD1 is measured. Does this perturbation cause a significant change in CYBRD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1490
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of ENSG00000250361. Does perturbing MEIS1 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of GYPB. Does perturbing MEIS1 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2001
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ENSG00000104894 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000104894 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor CD37 expression. Decide whether this perturbation leads to a significant alteration in CD37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":778
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of ENSG00000130656. Does perturbing BPGM lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of HBZ. Does perturbing BPGM lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":231
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ENSG00000011600 is measured. Determine whether ENSG00000011600 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2726
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ENSG00000011600 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000011600 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2728
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000254614 is measured. Does this perturbation cause a significant change in ENSG00000254614 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of AP003068.23 is measured. Does this perturbation cause a significant change in AP003068.23 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2610
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ENSG00000116871 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116871 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1933
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2288
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ENSG00000184384 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184384 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and MAML2 expression is observed. Does this perturbation lead to a significant difference in MAML2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1773
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2507
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and ENSG00000068078 expression is measured. Determine whether ENSG00000068078 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and FGFR3 expression is measured. Determine whether FGFR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2252
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2074
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ENSG00000118515 is measured. Does this perturbation cause a significant change in ENSG00000118515 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of SGK1 is measured. Does this perturbation cause a significant change in SGK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2550
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2249
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ENSG00000076356 expression is quantified. Does this perturbation result in a significant change in ENSG00000076356 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and PLXNA2 expression is quantified. Does this perturbation result in a significant change in PLXNA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1782
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000075624 is measured. Determine whether ENSG00000075624 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2866
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ENSG00000188536. Does this perturbation cause a significant change in ENSG00000188536 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HBA2. Does this perturbation cause a significant change in HBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1444
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ENSG00000184697 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184697 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CLDN6 expression. Decide whether this perturbation leads to a significant alteration in CLDN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":648
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of ENSG00000108821. Does perturbing COL1A1 lead to a significant change in ENSG00000108821 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of COL1A1. Does perturbing COL1A1 lead to a significant change in COL1A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":721
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of ENSG00000163499 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of CRYBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":967
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Does this perturbation cause a significant change in ENSG00000163513 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Does this perturbation cause a significant change in TGFBR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2820
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in ENSG00000245532 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in NEAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":595
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of ENSG00000068078 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of FGFR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is measured. Determine whether ENSG00000099625 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and C19orf26 expression is measured. Determine whether C19orf26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":249
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of ENSG00000163531 is measured. Does this perturbation cause a significant change in ENSG00000163531 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of NFASC is measured. Does this perturbation cause a significant change in NFASC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1760
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of ENSG00000168209. Does perturbing COL1A1 lead to a significant change in ENSG00000168209 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of DDIT4. Does perturbing COL1A1 lead to a significant change in DDIT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":731
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ENSG00000174498 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000174498 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1428
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000205542 is measured. Determine whether ENSG00000205542 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TMSB4X is measured. Determine whether TMSB4X shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2856
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2506
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ENSG00000079102. Does this perturbation cause a significant change in ENSG00000079102 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of RUNX1T1. Does this perturbation cause a significant change in RUNX1T1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2434
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENSG00000106991. Does perturbing PTPN13 lead to a significant change in ENSG00000106991 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENG. Does perturbing PTPN13 lead to a significant change in ENG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2311
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":275
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in ENSG00000123473 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in STIL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2745
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2500
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ENSG00000103241. Does this perturbation cause a significant change in ENSG00000103241 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1094
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1665
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is measured. Determine whether ENSG00000108984 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and MAP2K6 expression is measured. Determine whether MAP2K6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1839
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and ENSG00000142945 expression is quantified. Does this perturbation result in a significant change in ENSG00000142945 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1622
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of ENSG00000142945. Does this perturbation cause a significant change in ENSG00000142945 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1624
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ENSG00000170542. Does perturbing SET lead to a significant change in ENSG00000170542 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of SERPINB9. Does perturbing SET lead to a significant change in SERPINB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2531
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ENSG00000113594 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000113594 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor LIFR expression. Decide whether this perturbation leads to a significant alteration in LIFR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and ENSG00000163499 expression is quantified. Does this perturbation result in a significant change in ENSG00000163499 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and CRYBA2 expression is quantified. Does this perturbation result in a significant change in CRYBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":962
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2262
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ENSG00000140287 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of HDC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2177
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102804 is measured. Does this perturbation cause a significant change in ENSG00000102804 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of TSC22D1 is measured. Does this perturbation cause a significant change in TSC22D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2910
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ENSG00000188483. Does perturbing IER5L lead to a significant change in ENSG00000188483 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of IER5L. Does perturbing IER5L lead to a significant change in IER5L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1391
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ENSG00000184384 is measured. Determine whether ENSG00000184384 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of MAML2 is measured. Determine whether MAML2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1776
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ENSG00000118777 expression is quantified. Does this perturbation result in a significant change in ENSG00000118777 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ABCG2 expression is quantified. Does this perturbation result in a significant change in ABCG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3002
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ENSG00000184384. Does perturbing MAML2 lead to a significant change in ENSG00000184384 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of MAML2. Does perturbing MAML2 lead to a significant change in MAML2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1771
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Does this perturbation cause a significant change in ENSG00000153012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Does this perturbation cause a significant change in LGI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":490
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ENSG00000183770. Does this perturbation cause a significant change in ENSG00000183770 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1124
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ENSG00000117091 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of CD48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1307
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2715
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor ENSG00000135111 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135111 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor TBX3 expression. Decide whether this perturbation leads to a significant alteration in TBX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2818
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and ENSG00000277268 expression is observed. Does this perturbation lead to a significant difference in ENSG00000277268 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and RP11-445F12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-445F12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1723
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121068 is measured. Determine whether ENSG00000121068 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of TBX2 is measured. Determine whether TBX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2786
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and ENSG00000085185 expression is quantified. Does this perturbation result in a significant change in ENSG00000085185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and BCORL1 expression is quantified. Does this perturbation result in a significant change in BCORL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":182
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1890
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ENSG00000129757 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129757 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CDKN1C expression is observed. Does this perturbation lead to a significant difference in CDKN1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":413
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ENSG00000170608 expression is measured. Determine whether ENSG00000170608 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and FOXA3 expression is measured. Determine whether FOXA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1069
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1907
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor ENSG00000245848 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000245848 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor CEBPA expression. Decide whether this perturbation leads to a significant alteration in CEBPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":558
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000005187 is measured. Determine whether ENSG00000005187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1576
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ENSG00000005187 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":927
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and ENSG00000183019 expression is measured. Determine whether ENSG00000183019 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and MCEMP1 expression is measured. Determine whether MCEMP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":179
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and ENSG00000105223 expression is measured. Determine whether ENSG00000105223 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and PLD3 expression is measured. Determine whether PLD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1229
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000110492 is measured. Does this perturbation cause a significant change in ENSG00000110492 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of MDK is measured. Does this perturbation cause a significant change in MDK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2200
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ENSG00000148180. Does this perturbation cause a significant change in ENSG00000148180 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of GSN. Does this perturbation cause a significant change in GSN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1344
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1109
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2419
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor ENSG00000129514 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129514 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FOXA1 expression. Decide whether this perturbation leads to a significant alteration in FOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1028
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is measured. Determine whether ENSG00000174498 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1429
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ENSG00000158578. Does perturbing CDKN1A lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ALAS2. Does perturbing CDKN1A lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":381
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ENSG00000168140 expression is measured. Determine whether ENSG00000168140 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and VASN expression is measured. Determine whether VASN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2029
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":539
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ENSG00000077063. Does perturbing KIF18B lead to a significant change in ENSG00000077063 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CTTNBP2. Does perturbing KIF18B lead to a significant change in CTTNBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1611
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ENSG00000114315 expression is quantified. Does this perturbation result in a significant change in ENSG00000114315 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and HES1 expression is quantified. Does this perturbation result in a significant change in HES1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2032
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ENSG00000163520 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in FBLN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1185
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and ENSG00000179111 expression is observed. Does this perturbation lead to a significant difference in ENSG00000179111 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and HES7 expression is observed. Does this perturbation lead to a significant difference in HES7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1203
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ENSG00000279576 expression is quantified. Does this perturbation result in a significant change in ENSG00000279576 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and AP000769.1 expression is quantified. Does this perturbation result in a significant change in AP000769.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1942
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2596
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ENSG00000250361. Does perturbing POU3F2 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of GYPB. Does perturbing POU3F2 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2181
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Does this perturbation cause a significant change in ENSG00000121900 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Does this perturbation cause a significant change in TMEM54 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2760
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ENSG00000205542 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TMSB4X indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2857
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of ENSG00000069011. Does perturbing HES7 lead to a significant change in ENSG00000069011 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of PITX1. Does perturbing HES7 lead to a significant change in PITX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1211
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Determine whether ENSG00000163499 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Determine whether CRYBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":966
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ENSG00000168140 expression is observed. Does this perturbation lead to a significant difference in ENSG00000168140 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and VASN expression is observed. Does this perturbation lead to a significant difference in VASN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2023
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENSG00000186051 expression is measured. Determine whether ENSG00000186051 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and TAL2 expression is measured. Determine whether TAL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2339
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2906
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":698
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and ENSG00000163531 expression is measured. Determine whether ENSG00000163531 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and NFASC expression is measured. Determine whether NFASC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1769
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":422
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ENSG00000115255. Does this perturbation cause a significant change in ENSG00000115255 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of REEP6. Does this perturbation cause a significant change in REEP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":624
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ENSG00000115758 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ODC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ENSG00000177606 expression is measured. Determine whether ENSG00000177606 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and JUN expression is measured. Determine whether JUN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1589
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and ENSG00000004939 expression is quantified. Does this perturbation result in a significant change in ENSG00000004939 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and SLC4A1 expression is quantified. Does this perturbation result in a significant change in SLC4A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2632
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of ENSG00000179111 is measured. Determine whether ENSG00000179111 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of HES7 is measured. Determine whether HES7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1206
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of ENSG00000255346 is measured. Does this perturbation cause a significant change in ENSG00000255346 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of NOX5 is measured. Does this perturbation cause a significant change in NOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2890
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1897
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1100
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1667
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and ENSG00000205277 expression is measured. Determine whether ENSG00000205277 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and MUC12 expression is measured. Determine whether MUC12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3139
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in ENSG00000273706 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1715
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ENSG00000103241 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000103241 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1098
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2575
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ENSG00000186185. Does perturbing KIF18B lead to a significant change in ENSG00000186185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of KIF18B. Does perturbing KIF18B lead to a significant change in KIF18B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1601
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ENSG00000188536. Does perturbing IKZF3 lead to a significant change in ENSG00000188536 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HBA2. Does perturbing IKZF3 lead to a significant change in HBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1441
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ENSG00000130176 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CNN1 expression. Decide whether this perturbation leads to a significant alteration in CNN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":668
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1406
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ENSG00000149516. Does this perturbation cause a significant change in ENSG00000149516 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of MS4A3. Does this perturbation cause a significant change in MS4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":994
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000120738 is measured. Does this perturbation cause a significant change in ENSG00000120738 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of EGR1 is measured. Does this perturbation cause a significant change in EGR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2660
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2283
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000115758 is measured. Determine whether ENSG00000115758 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ODC1 is measured. Determine whether ODC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of ENSG00000026297. Does this perturbation cause a significant change in ENSG00000026297 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of RNASET2. Does this perturbation cause a significant change in RNASET2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":834
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is quantified. Does this perturbation result in a significant change in ENSG00000196565 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and HBG2 expression is quantified. Does this perturbation result in a significant change in HBG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":302
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":792
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ENSG00000105610 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in KLF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1675
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ENSG00000116871. Does perturbing MAP7D1 lead to a significant change in ENSG00000116871 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1921
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000187997 is measured. Determine whether ENSG00000187997 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of C17orf99 is measured. Determine whether C17orf99 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":436
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ENSG00000260793. Does this perturbation cause a significant change in ENSG00000260793 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP5-882C2.2. Does this perturbation cause a significant change in RP5-882C2.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2144
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Does this perturbation cause a significant change in ENSG00000070214 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Does this perturbation cause a significant change in SLC44A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3010
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is measured. Determine whether ENSG00000129514 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FOXA1 expression is measured. Determine whether FOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1029
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in ENSG00000004939 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in SLC4A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2635
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ENSG00000129757 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CDKN1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":417
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ENSG00000115255 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in REEP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":625
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and ENSG00000164920 expression is quantified. Does this perturbation result in a significant change in ENSG00000164920 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and OSR2 expression is quantified. Does this perturbation result in a significant change in OSR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2112
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2186
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ENSG00000166501. Does this perturbation cause a significant change in ENSG00000166501 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2544
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and ENSG00000101076 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101076 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and HNF4A expression is observed. Does this perturbation lead to a significant difference in HNF4A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1263
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1527
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of ENSG00000179111. Does perturbing HES7 lead to a significant change in ENSG00000179111 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of HES7. Does perturbing HES7 lead to a significant change in HES7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1201
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000170180 is measured. Does this perturbation cause a significant change in ENSG00000170180 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of GYPA is measured. Does this perturbation cause a significant change in GYPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":710
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of ENSG00000160838. Does this perturbation cause a significant change in ENSG00000160838 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of LRRC71. Does this perturbation cause a significant change in LRRC71 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ENSG00000163513 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in TGFBR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2835
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ENSG00000142669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of SH3BGRL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":797
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":533
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ENSG00000196565. Does this perturbation cause a significant change in ENSG00000196565 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of HBG2. Does this perturbation cause a significant change in HBG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":314
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ENSG00000134294 expression is quantified. Does this perturbation result in a significant change in ENSG00000134294 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and SLC38A2 expression is quantified. Does this perturbation result in a significant change in SLC38A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2582
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ENSG00000266976 expression is observed. Does this perturbation lead to a significant difference in ENSG00000266976 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and AC079466.1 expression is observed. Does this perturbation lead to a significant difference in AC079466.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1853
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of ENSG00000240065 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1487
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENSG00000182871. Does perturbing PTPN13 lead to a significant change in ENSG00000182871 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of COL18A1. Does perturbing PTPN13 lead to a significant change in COL18A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2321
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2490
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and ENSG00000108821 expression is observed. Does this perturbation lead to a significant difference in ENSG00000108821 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and COL1A1 expression is observed. Does this perturbation lead to a significant difference in COL1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":723
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of ENSG00000166340. Does this perturbation cause a significant change in ENSG00000166340 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of TPP1. Does this perturbation cause a significant change in TPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1154
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2579
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1510
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":350
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ENSG00000188536 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188536 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HBA2 expression. Decide whether this perturbation leads to a significant alteration in HBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1448
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and ENSG00000092067 expression is quantified. Does this perturbation result in a significant change in ENSG00000092067 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CEBPE expression is quantified. Does this perturbation result in a significant change in CEBPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":522
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of ENSG00000255346 is measured. Determine whether ENSG00000255346 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of NOX5 is measured. Determine whether NOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2896
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ENSG00000170689 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170689 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor HOXB9 expression. Decide whether this perturbation leads to a significant alteration in HOXB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1328
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of ENSG00000121900. Does this perturbation cause a significant change in ENSG00000121900 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of TMEM54. Does this perturbation cause a significant change in TMEM54 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2764
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and ENSG00000143498 expression is measured. Determine whether ENSG00000143498 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and TAF1A expression is measured. Determine whether TAF1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2739
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1524
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ENSG00000204472 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":945
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and ENSG00000196188 expression is quantified. Does this perturbation result in a significant change in ENSG00000196188 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CTSE expression is quantified. Does this perturbation result in a significant change in CTSE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1272
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor ENSG00000141753 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141753 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor IGFBP4 expression. Decide whether this perturbation leads to a significant alteration in IGFBP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2968
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ENSG00000159556. Does this perturbation cause a significant change in ENSG00000159556 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of ISL2. Does this perturbation cause a significant change in ISL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1504
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ENSG00000168140 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000168140 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor VASN expression. Decide whether this perturbation leads to a significant alteration in VASN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2028
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":454
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENSG00000186051 expression is observed. Does this perturbation lead to a significant difference in ENSG00000186051 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and TAL2 expression is observed. Does this perturbation lead to a significant difference in TAL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2333
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ENSG00000106546. Does perturbing AHR lead to a significant change in ENSG00000106546 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of AHR. Does perturbing AHR lead to a significant change in AHR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of ENSG00000127831. Does this perturbation cause a significant change in ENSG00000127831 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of VIL1. Does this perturbation cause a significant change in VIL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1754
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Does this perturbation cause a significant change in ENSG00000070214 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Does this perturbation cause a significant change in SLC44A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3020
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ENSG00000108984 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in MAP2K6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1845
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Determine whether ENSG00000157557 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Determine whether ETS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":956
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1824
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of ENSG00000118058 is measured. Determine whether ENSG00000118058 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of KMT2A is measured. Determine whether KMT2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1686
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ENSG00000070214 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070214 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor SLC44A1 expression. Decide whether this perturbation leads to a significant alteration in SLC44A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1178
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENSG00000186051 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000186051 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor TAL2 expression. Decide whether this perturbation leads to a significant alteration in TAL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2338
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ENSG00000159388 is measured. Determine whether ENSG00000159388 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1556
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000134294 is measured. Determine whether ENSG00000134294 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Determine whether SLC38A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2586
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of ENSG00000092067. Does this perturbation cause a significant change in ENSG00000092067 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CEBPE. Does this perturbation cause a significant change in CEBPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":514
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1407
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ENSG00000137841 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in PLCB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2135
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":270
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of ENSG00000237330 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of RNF223 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2407
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ENSG00000166450. Does this perturbation cause a significant change in ENSG00000166450 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of PRTG. Does this perturbation cause a significant change in PRTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2224
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ENSG00000129757. Does this perturbation cause a significant change in ENSG00000129757 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CDKN1C. Does this perturbation cause a significant change in CDKN1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":414
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and ENSG00000004939 expression is observed. Does this perturbation lead to a significant difference in ENSG00000004939 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and SLC4A1 expression is observed. Does this perturbation lead to a significant difference in SLC4A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2633
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of ENSG00000240065 is measured. Determine whether ENSG00000240065 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of PSMB9 is measured. Determine whether PSMB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1486
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ENSG00000196565 expression is measured. Determine whether ENSG00000196565 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and HBG2 expression is measured. Determine whether HBG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2399
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000206172 is measured. Does this perturbation cause a significant change in ENSG00000206172 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of HBA1 is measured. Does this perturbation cause a significant change in HBA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2460
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ENSG00000116871 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1927
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ENSG00000158578. Does perturbing IGDCC3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of ALAS2. Does perturbing IGDCC3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1431
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":686
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ENSG00000124762 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":367
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2849
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor ENSG00000163531 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163531 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor NFASC expression. Decide whether this perturbation leads to a significant alteration in NFASC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1768
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of ENSG00000158517. Does this perturbation cause a significant change in ENSG00000158517 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of NCF1. Does this perturbation cause a significant change in NCF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":474
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ENSG00000184486 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in POU3F2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2165
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2689
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of ENSG00000168209. Does this perturbation cause a significant change in ENSG00000168209 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of DDIT4. Does this perturbation cause a significant change in DDIT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":734
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1878
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ENSG00000115758 expression is measured. Determine whether ENSG00000115758 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ODC1 expression is measured. Determine whether ODC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and ENSG00000104903 expression is quantified. Does this perturbation result in a significant change in ENSG00000104903 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and LYL1 expression is quantified. Does this perturbation result in a significant change in LYL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1742
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and ENSG00000119535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":583
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of ENSG00000135111. Does perturbing TBX3 lead to a significant change in ENSG00000135111 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of TBX3. Does perturbing TBX3 lead to a significant change in TBX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2811
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and ENSG00000141753 expression is quantified. Does this perturbation result in a significant change in ENSG00000141753 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and IGFBP4 expression is quantified. Does this perturbation result in a significant change in IGFBP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2962
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ENSG00000166450 expression is quantified. Does this perturbation result in a significant change in ENSG00000166450 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and PRTG expression is quantified. Does this perturbation result in a significant change in PRTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2222
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ENSG00000119969 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119969 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and HELLS expression is observed. Does this perturbation lead to a significant difference in HELLS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2153
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ENSG00000114315. Does perturbing MIDN lead to a significant change in ENSG00000114315 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of HES1. Does perturbing MIDN lead to a significant change in HES1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2031
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ENSG00000005187 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1575
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ENSG00000113594 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in LIFR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1795
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ENSG00000204472 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1965
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ENSG00000119535. Does perturbing SGK1 lead to a significant change in ENSG00000119535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of CSF3R. Does perturbing SGK1 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2561
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ENSG00000070214 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070214 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and SLC44A1 expression is observed. Does this perturbation lead to a significant difference in SLC44A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3013
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and ENSG00000166340 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166340 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and TPP1 expression is observed. Does this perturbation lead to a significant difference in TPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1153
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ENSG00000174498 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1415
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor ENSG00000135409 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135409 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":228
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ENSG00000213934 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000213934 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor HBG1 expression. Decide whether this perturbation leads to a significant alteration in HBG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":328
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ENSG00000183770 expression is measured. Determine whether ENSG00000183770 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":299
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ENSG00000070214 expression is measured. Determine whether ENSG00000070214 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and SLC44A1 expression is measured. Determine whether SLC44A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1179
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ENSG00000187997. Does this perturbation cause a significant change in ENSG00000187997 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of C17orf99. Does this perturbation cause a significant change in C17orf99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":434
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and ENSG00000188536 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188536 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and HBA2 expression is observed. Does this perturbation lead to a significant difference in HBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2473
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ENSG00000108984 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of MAP2K6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1847
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and ENSG00000179111 expression is quantified. Does this perturbation result in a significant change in ENSG00000179111 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and HES7 expression is quantified. Does this perturbation result in a significant change in HES7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1202
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and ENSG00000101200 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101200 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2793
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of ENSG00000143498. Does perturbing STIL lead to a significant change in ENSG00000143498 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of TAF1A. Does perturbing STIL lead to a significant change in TAF1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2731
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Does this perturbation cause a significant change in ENSG00000258274 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Does this perturbation cause a significant change in RP11-887P2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1360
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of ENSG00000101200 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2797
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ENSG00000163520 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163520 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and FBLN2 expression is observed. Does this perturbation lead to a significant difference in FBLN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1183
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ENSG00000234965. Does perturbing SET lead to a significant change in ENSG00000234965 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of SHISA8. Does perturbing SET lead to a significant change in SHISA8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2521
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ENSG00000158578. Does perturbing CLDN6 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ALAS2. Does perturbing CLDN6 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":651
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and ENSG00000153012 expression is measured. Determine whether ENSG00000153012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and LGI2 expression is measured. Determine whether LGI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":499
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ENSG00000204472 expression is measured. Determine whether ENSG00000204472 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1969
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000158869 is measured. Does this perturbation cause a significant change in ENSG00000158869 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3050
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ENSG00000115053 expression is measured. Determine whether ENSG00000115053 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and NCL expression is measured. Determine whether NCL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2049
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000129757 is measured. Does this perturbation cause a significant change in ENSG00000129757 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CDKN1C is measured. Does this perturbation cause a significant change in CDKN1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":410
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":560
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ENSG00000184009 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ACTG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2875
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ENSG00000196565 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in HBG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":305
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1999
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in ENSG00000158517 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in NCF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":475
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2250
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and ENSG00000121068 expression is observed. Does this perturbation lead to a significant difference in ENSG00000121068 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and TBX2 expression is observed. Does this perturbation lead to a significant difference in TBX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2783
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and ENSG00000105223 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105223 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and PLD3 expression is observed. Does this perturbation lead to a significant difference in PLD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1223
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ENSG00000158578. Does perturbing DUSP9 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ALAS2. Does perturbing DUSP9 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":851
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":695
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and ENSG00000188536 expression is measured. Determine whether ENSG00000188536 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and HBA2 expression is measured. Determine whether HBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2479
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":384
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ENSG00000133317. Does perturbing RUNX1T1 lead to a significant change in ENSG00000133317 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of LGALS12. Does perturbing RUNX1T1 lead to a significant change in LGALS12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2451
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and ENSG00000030110 expression is quantified. Does this perturbation result in a significant change in ENSG00000030110 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":142
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and ENSG00000227053 expression is measured. Determine whether ENSG00000227053 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and RP11-395B7.4 expression is measured. Determine whether RP11-395B7.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3129
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of ENSG00000279529 is measured. Determine whether ENSG00000279529 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of CTD-3222D19.8 is measured. Determine whether CTD-3222D19.8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1646
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of ENSG00000265972 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1247
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ENSG00000159388 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159388 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1558
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3045
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":409
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2255
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2657
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ENSG00000115738 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ID2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2017
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ENSG00000159388. Does perturbing JUN lead to a significant change in ENSG00000159388 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of BTG2. Does perturbing JUN lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1551
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor ENSG00000273706 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000273706 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":128
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ENSG00000189171. Does perturbing SNAI1 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of S100A13. Does perturbing SNAI1 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2691
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000166340 is measured. Does this perturbation cause a significant change in ENSG00000166340 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1150
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is quantified. Does this perturbation result in a significant change in ENSG00000108984 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and MAP2K6 expression is quantified. Does this perturbation result in a significant change in MAP2K6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1832
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of ENSG00000245848 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of CEBPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":557
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ENSG00000069535 is measured. Does this perturbation cause a significant change in ENSG00000069535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of MAOB is measured. Does this perturbation cause a significant change in MAOB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1530
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1513
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Determine whether ENSG00000129514 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Determine whether FOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1036
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Determine whether ENSG00000166450 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Determine whether PRTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2226
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Does this perturbation cause a significant change in ENSG00000101200 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2790
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ENSG00000158373 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in HIST1H2BD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2095
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ENSG00000157557 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ETS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":957
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ENSG00000106031. Does perturbing HOXA13 lead to a significant change in ENSG00000106031 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of HOXA13. Does perturbing HOXA13 lead to a significant change in HOXA13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1291
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1812
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and ENSG00000101076 expression is quantified. Does this perturbation result in a significant change in ENSG00000101076 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and HNF4A expression is quantified. Does this perturbation result in a significant change in HNF4A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1262
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ENSG00000183770 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183770 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1123
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Determine whether ENSG00000092067 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Determine whether CEBPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":516
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ENSG00000100097 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":807
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1430
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2909
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of ENSG00000169410. Does perturbing PTPN9 lead to a significant change in ENSG00000169410 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PTPN9. Does perturbing PTPN9 lead to a significant change in PTPN9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2341
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and ENSG00000203989 expression is observed. Does this perturbation lead to a significant difference in ENSG00000203989 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and RHOXF2BB expression is observed. Does this perturbation lead to a significant difference in RHOXF2BB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2753
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of ENSG00000196517 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of SLC6A9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2647
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":277
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ENSG00000002586 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of CD99 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":337
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ENSG00000128016 expression is measured. Determine whether ENSG00000128016 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ZFP36 expression is measured. Determine whether ZFP36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2059
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and ENSG00000227053 expression is quantified. Does this perturbation result in a significant change in ENSG00000227053 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and RP11-395B7.4 expression is quantified. Does this perturbation result in a significant change in RP11-395B7.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3122
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ENSG00000115255 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of REEP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":627
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1133
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2189
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ENSG00000204472 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":947
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in ENSG00000090238 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in YPEL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1165
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of ENSG00000121068 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of TBX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2787
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1819
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ENSG00000143401 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ANP32E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2087
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of ENSG00000273706 is measured. Does this perturbation cause a significant change in ENSG00000273706 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1710
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000148180 is measured. Determine whether ENSG00000148180 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of GSN is measured. Determine whether GSN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1346
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000143369 is measured. Determine whether ENSG00000143369 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ECM1 is measured. Determine whether ECM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2306
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of ENSG00000185198. Does perturbing UBASH3B lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of PRSS57. Does perturbing UBASH3B lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2991
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ENSG00000140545 is measured. Does this perturbation cause a significant change in ENSG00000140545 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":610
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ENSG00000166501 expression is measured. Determine whether ENSG00000166501 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2549
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ENSG00000116871 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000116871 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1928
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ENSG00000140545 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000140545 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":618
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Determine whether ENSG00000124762 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":366
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ENSG00000204472 expression is measured. Determine whether ENSG00000204472 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":949
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of ENSG00000123473. Does this perturbation cause a significant change in ENSG00000123473 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of STIL. Does this perturbation cause a significant change in STIL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2744
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ENSG00000118777 expression is observed. Does this perturbation lead to a significant difference in ENSG00000118777 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ABCG2 expression is observed. Does this perturbation lead to a significant difference in ABCG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3003
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ENSG00000159388 expression is quantified. Does this perturbation result in a significant change in ENSG00000159388 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1552
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of ENSG00000120738. Does perturbing SLC6A9 lead to a significant change in ENSG00000120738 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of EGR1. Does perturbing SLC6A9 lead to a significant change in EGR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2661
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ENSG00000115255 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115255 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor REEP6 expression. Decide whether this perturbation leads to a significant alteration in REEP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":628
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ENSG00000079102. Does perturbing RUNX1T1 lead to a significant change in ENSG00000079102 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of RUNX1T1. Does perturbing RUNX1T1 lead to a significant change in RUNX1T1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2431
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and ENSG00000117139 expression is measured. Determine whether ENSG00000117139 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and KDM5B expression is measured. Determine whether KDM5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3149
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ENSG00000234965 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in SHISA8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2525
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and ENSG00000197965 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197965 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and MPZL1 expression is observed. Does this perturbation lead to a significant difference in MPZL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2123
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000115758 is measured. Does this perturbation cause a significant change in ENSG00000115758 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ODC1 is measured. Does this perturbation cause a significant change in ODC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ENSG00000158373 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of HIST1H2BD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2097
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of ENSG00000125931. Does perturbing CITED1 lead to a significant change in ENSG00000125931 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of CITED1. Does perturbing CITED1 lead to a significant change in CITED1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":571
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":566
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of ENSG00000119535 is measured. Does this perturbation cause a significant change in ENSG00000119535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":580
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and ENSG00000277268 expression is quantified. Does this perturbation result in a significant change in ENSG00000277268 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and RP11-445F12.1 expression is quantified. Does this perturbation result in a significant change in RP11-445F12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1722
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ENSG00000005187 expression is quantified. Does this perturbation result in a significant change in ENSG00000005187 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1572
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of ENSG00000115844. Does perturbing DLX2 lead to a significant change in ENSG00000115844 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of DLX2. Does perturbing DLX2 lead to a significant change in DLX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":811
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000206172 is measured. Determine whether ENSG00000206172 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of HBA1 is measured. Determine whether HBA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2466
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1827
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1437
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2387
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000188536 is measured. Does this perturbation cause a significant change in ENSG00000188536 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HBA2 is measured. Does this perturbation cause a significant change in HBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1440
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ENSG00000197766 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197766 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor CFD expression. Decide whether this perturbation leads to a significant alteration in CFD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2068
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and ENSG00000254614 expression is quantified. Does this perturbation result in a significant change in ENSG00000254614 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and AP003068.23 expression is quantified. Does this perturbation result in a significant change in AP003068.23 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2612
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ENSG00000102804 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of TSC22D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":287
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2908
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Determine whether ENSG00000070214 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Determine whether SLC44A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3026
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and ENSG00000273706 expression is measured. Determine whether ENSG00000273706 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":129
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000153094 is measured. Does this perturbation cause a significant change in ENSG00000153094 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Does this perturbation cause a significant change in BCL2L11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":150
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and ENSG00000163531 expression is quantified. Does this perturbation result in a significant change in ENSG00000163531 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and NFASC expression is quantified. Does this perturbation result in a significant change in NFASC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1762
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":867
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000135047 is measured. Determine whether ENSG00000135047 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1886
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ENSG00000113369. Does perturbing ARRDC3 lead to a significant change in ENSG00000113369 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ARRDC3. Does perturbing ARRDC3 lead to a significant change in ARRDC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2195
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of ENSG00000111057. Does this perturbation cause a significant change in ENSG00000111057 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of KRT18. Does this perturbation cause a significant change in KRT18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":194
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor ENSG00000265972 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000265972 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1248
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and ENSG00000197965 expression is quantified. Does this perturbation result in a significant change in ENSG00000197965 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and MPZL1 expression is quantified. Does this perturbation result in a significant change in MPZL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2122
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1462
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ENSG00000156030 expression is measured. Determine whether ENSG00000156030 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ELMSAN1 expression is measured. Determine whether ELMSAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":919
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ENSG00000109099 expression is quantified. Does this perturbation result in a significant change in ENSG00000109099 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and PMP22 expression is quantified. Does this perturbation result in a significant change in PMP22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1192
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Determine whether ENSG00000121900 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Determine whether TMEM54 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2776
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ENSG00000186185 expression is measured. Determine whether ENSG00000186185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and KIF18B expression is measured. Determine whether KIF18B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1609
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is measured. Determine whether ENSG00000139219 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and COL2A1 expression is measured. Determine whether COL2A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":769
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ENSG00000077063 expression is observed. Does this perturbation lead to a significant difference in ENSG00000077063 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and CTTNBP2 expression is observed. Does this perturbation lead to a significant difference in CTTNBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3073
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121068 is measured. Does this perturbation cause a significant change in ENSG00000121068 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of TBX2 is measured. Does this perturbation cause a significant change in TBX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2780
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1405
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of ENSG00000004939 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of SLC4A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2637
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2417
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ENSG00000133317 expression is quantified. Does this perturbation result in a significant change in ENSG00000133317 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and LGALS12 expression is quantified. Does this perturbation result in a significant change in LGALS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2452
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ENSG00000279669 expression is quantified. Does this perturbation result in a significant change in ENSG00000279669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and RP11-717F1.1 expression is quantified. Does this perturbation result in a significant change in RP11-717F1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2672
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1996
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Determine whether ENSG00000005187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":926
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ENSG00000115255 is measured. Determine whether ENSG00000115255 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of REEP6 is measured. Determine whether REEP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":626
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in ENSG00000160838 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in LRRC71 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and ENSG00000090382 expression is quantified. Does this perturbation result in a significant change in ENSG00000090382 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and LYZ expression is quantified. Does this perturbation result in a significant change in LYZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1042
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of ENSG00000115844. Does this perturbation cause a significant change in ENSG00000115844 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of DLX2. Does this perturbation cause a significant change in DLX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":814
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ENSG00000128016 expression is quantified. Does this perturbation result in a significant change in ENSG00000128016 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ZFP36 expression is quantified. Does this perturbation result in a significant change in ZFP36 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2052
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ENSG00000102575 expression is quantified. Does this perturbation result in a significant change in ENSG00000102575 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ACP5 expression is quantified. Does this perturbation result in a significant change in ACP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2932
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ENSG00000137841 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000137841 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor PLCB2 expression. Decide whether this perturbation leads to a significant alteration in PLCB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2138
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ENSG00000106031. Does this perturbation cause a significant change in ENSG00000106031 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of HOXA13. Does this perturbation cause a significant change in HOXA13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1294
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":348
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ENSG00000135047. Does perturbing MAP4K3 lead to a significant change in ENSG00000135047 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of CTSL. Does perturbing MAP4K3 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1881
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2650
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of ENSG00000115844. Does this perturbation cause a significant change in ENSG00000115844 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of DLX2. Does this perturbation cause a significant change in DLX2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":824
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ENSG00000090382 expression is quantified. Does this perturbation result in a significant change in ENSG00000090382 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LYZ expression is quantified. Does this perturbation result in a significant change in LYZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1052
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of ENSG00000130656. Does perturbing SAMD1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HBZ. Does perturbing SAMD1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2491
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in ENSG00000115844 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in DLX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":815
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ENSG00000118777. Does this perturbation cause a significant change in ENSG00000118777 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ABCG2. Does this perturbation cause a significant change in ABCG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3004
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1993
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ENSG00000143674 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143674 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and KIAA1804 expression is observed. Does this perturbation lead to a significant difference in KIAA1804 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1563
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1958
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ENSG00000077063 expression is observed. Does this perturbation lead to a significant difference in ENSG00000077063 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CTTNBP2 expression is observed. Does this perturbation lead to a significant difference in CTTNBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1613
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1255
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in ENSG00000168209 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in DDIT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":735
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and ENSG00000111057 expression is measured. Determine whether ENSG00000111057 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and KRT18 expression is measured. Determine whether KRT18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":199
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ENSG00000204482. Does perturbing SPI1 lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of LST1. Does perturbing SPI1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2701
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":897
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and ENSG00000159399 expression is quantified. Does this perturbation result in a significant change in ENSG00000159399 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and HK2 expression is quantified. Does this perturbation result in a significant change in HK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1232
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ENSG00000197766 is measured. Does this perturbation cause a significant change in ENSG00000197766 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of CFD is measured. Does this perturbation cause a significant change in CFD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2060
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ENSG00000115053. Does this perturbation cause a significant change in ENSG00000115053 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of NCL. Does this perturbation cause a significant change in NCL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2044
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2370
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ENSG00000002586 expression is measured. Determine whether ENSG00000002586 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and CD99 expression is measured. Determine whether CD99 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":339
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ENSG00000196565 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196565 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor HBG2 expression. Decide whether this perturbation leads to a significant alteration in HBG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":318
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ENSG00000104894 expression is observed. Does this perturbation lead to a significant difference in ENSG00000104894 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and CD37 expression is observed. Does this perturbation lead to a significant difference in CD37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":773
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ENSG00000256713. Does this perturbation cause a significant change in ENSG00000256713 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PGA5. Does this perturbation cause a significant change in PGA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":704
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2994
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Does this perturbation cause a significant change in ENSG00000188483 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Does this perturbation cause a significant change in IER5L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1390
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1986
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ENSG00000110492 expression is observed. Does this perturbation lead to a significant difference in ENSG00000110492 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and MDK expression is observed. Does this perturbation lead to a significant difference in MDK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2203
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2005
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ENSG00000119535 is measured. Determine whether ENSG00000119535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2566
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ENSG00000111348 expression is observed. Does this perturbation lead to a significant difference in ENSG00000111348 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1973
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000102804 is measured. Does this perturbation cause a significant change in ENSG00000102804 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of TSC22D1 is measured. Does this perturbation cause a significant change in TSC22D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":280
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ENSG00000139219 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in COL2A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":765
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Determine whether ENSG00000005187 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Determine whether ACSM3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":906
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ENSG00000144655 expression is observed. Does this perturbation lead to a significant difference in ENSG00000144655 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and CSRNP1 expression is observed. Does this perturbation lead to a significant difference in CSRNP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":783
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":562
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000187997 is measured. Does this perturbation cause a significant change in ENSG00000187997 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of C17orf99 is measured. Does this perturbation cause a significant change in C17orf99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":430
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3049
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of ENSG00000237330 is measured. Does this perturbation cause a significant change in ENSG00000237330 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of RNF223 is measured. Does this perturbation cause a significant change in RNF223 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2400
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and ENSG00000135409 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135409 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":223
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ENSG00000137841 expression is observed. Does this perturbation lead to a significant difference in ENSG00000137841 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and PLCB2 expression is observed. Does this perturbation lead to a significant difference in PLCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2133
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ENSG00000134294 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in SLC38A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2585
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in ENSG00000125144 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in MT1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":205
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ENSG00000204472 is measured. Determine whether ENSG00000204472 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":946
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is quantified. Does this perturbation result in a significant change in ENSG00000183770 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1112
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ENSG00000174498 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000174498 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1418
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of ENSG00000101200 is measured. Does this perturbation cause a significant change in ENSG00000101200 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2800
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is quantified. Does this perturbation result in a significant change in ENSG00000139219 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and COL2A1 expression is quantified. Does this perturbation result in a significant change in COL2A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":752
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ENSG00000005187. Does perturbing ELMSAN1 lead to a significant change in ENSG00000005187 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ACSM3. Does perturbing ELMSAN1 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":921
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Determine whether ENSG00000130176 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Determine whether CNN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":666
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ENSG00000110492 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in MDK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2205
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ENSG00000135047 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135047 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1883
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000140287 is measured. Determine whether ENSG00000140287 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of HDC is measured. Determine whether HDC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2176
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000206172 is measured. Does this perturbation cause a significant change in ENSG00000206172 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of HBA1 is measured. Does this perturbation cause a significant change in HBA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2270
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ENSG00000106031 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in HOXA13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1295
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ENSG00000130176 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CNN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":665
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of ENSG00000160185. Does this perturbation cause a significant change in ENSG00000160185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2944
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2280
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ENSG00000177606 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of JUN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1587
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ENSG00000113594. Does perturbing MAML2 lead to a significant change in ENSG00000113594 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of LIFR. Does perturbing MAML2 lead to a significant change in LIFR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1791
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000279576 is measured. Does this perturbation cause a significant change in ENSG00000279576 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of AP000769.1 is measured. Does this perturbation cause a significant change in AP000769.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1940
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000169413 is measured. Determine whether ENSG00000169413 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of RNASE6 is measured. Determine whether RNASE6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1916
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2710
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1400
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ENSG00000166450 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166450 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and PRTG expression is observed. Does this perturbation lead to a significant difference in PRTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2223
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ENSG00000258274 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of RP11-887P2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1317
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of ENSG00000277268 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of RP11-445F12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1727
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1005
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ENSG00000188483 expression is quantified. Does this perturbation result in a significant change in ENSG00000188483 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and IER5L expression is quantified. Does this perturbation result in a significant change in IER5L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1382
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of ENSG00000164687 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1697
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of ENSG00000154127. Does perturbing UBASH3B lead to a significant change in ENSG00000154127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2971
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ENSG00000118515 expression is measured. Determine whether ENSG00000118515 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and SGK1 expression is measured. Determine whether SGK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2559
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ENSG00000168140. Does this perturbation cause a significant change in ENSG00000168140 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of VASN. Does this perturbation cause a significant change in VASN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2024
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of ENSG00000185198. Does perturbing HK2 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of PRSS57. Does perturbing HK2 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1251
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":875
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000104894 is measured. Does this perturbation cause a significant change in ENSG00000104894 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of CD37 is measured. Does this perturbation cause a significant change in CD37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":770
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1438
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and ENSG00000159399 expression is measured. Determine whether ENSG00000159399 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and HK2 expression is measured. Determine whether HK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1239
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor ENSG00000203989 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000203989 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor RHOXF2BB expression. Decide whether this perturbation leads to a significant alteration in RHOXF2BB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2758
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3114
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ENSG00000102804. Does this perturbation cause a significant change in ENSG00000102804 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of TSC22D1. Does this perturbation cause a significant change in TSC22D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":284
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1013
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of ENSG00000204482. Does perturbing CEBPE lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of LST1. Does perturbing CEBPE lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":531
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in ENSG00000143498 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in TAF1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2735
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ENSG00000105610 is measured. Determine whether ENSG00000105610 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of KLF1 is measured. Determine whether KLF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1676
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENSG00000106991 expression is observed. Does this perturbation lead to a significant difference in ENSG00000106991 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENG expression is observed. Does this perturbation lead to a significant difference in ENG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2313
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ENSG00000158373 expression is measured. Determine whether ENSG00000158373 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and HIST1H2BD expression is measured. Determine whether HIST1H2BD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2099
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of ENSG00000197965. Does this perturbation cause a significant change in ENSG00000197965 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of MPZL1. Does this perturbation cause a significant change in MPZL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2124
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of ENSG00000206172. Does this perturbation cause a significant change in ENSG00000206172 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of HBA1. Does this perturbation cause a significant change in HBA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2464
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2504
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in ENSG00000101200 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2805
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and ENSG00000090238 expression is observed. Does this perturbation lead to a significant difference in ENSG00000090238 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and YPEL3 expression is observed. Does this perturbation lead to a significant difference in YPEL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1163
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000113369 is measured. Does this perturbation cause a significant change in ENSG00000113369 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ARRDC3 is measured. Does this perturbation cause a significant change in ARRDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2840
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor ENSG00000085185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000085185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor BCORL1 expression. Decide whether this perturbation leads to a significant alteration in BCORL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":188
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2418
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000162493 is measured. Determine whether ENSG00000162493 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PDPN is measured. Determine whether PDPN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2626
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ENSG00000070214 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of SLC44A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3017
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ENSG00000158373 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158373 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and HIST1H2BD expression is observed. Does this perturbation lead to a significant difference in HIST1H2BD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2093
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2515
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in ENSG00000169410 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PTPN9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2355
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2656
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of ENSG00000245848. Does this perturbation cause a significant change in ENSG00000245848 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of CEBPA. Does this perturbation cause a significant change in CEBPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":554
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ENSG00000134294 expression is measured. Determine whether ENSG00000134294 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and SLC38A2 expression is measured. Determine whether SLC38A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2589
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of ENSG00000071967. Does this perturbation cause a significant change in ENSG00000071967 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of CYBRD1. Does this perturbation cause a significant change in CYBRD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1494
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Does this perturbation cause a significant change in ENSG00000139219 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Does this perturbation cause a significant change in COL2A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":760
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of ENSG00000120738. Does this perturbation cause a significant change in ENSG00000120738 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of EGR1. Does this perturbation cause a significant change in EGR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2664
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of ENSG00000204482. Does perturbing CEBPA lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of LST1. Does perturbing CEBPA lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":451
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ENSG00000177606 expression is quantified. Does this perturbation result in a significant change in ENSG00000177606 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and JUN expression is quantified. Does this perturbation result in a significant change in JUN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1582
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in ENSG00000101076 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in HNF4A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1265
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2373
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Determine whether ENSG00000174498 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1426
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000183770 is measured. Determine whether ENSG00000183770 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":296
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and ENSG00000105697 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105697 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and HAMP expression is observed. Does this perturbation lead to a significant difference in HAMP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2483
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2426
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ENSG00000266976 expression is quantified. Does this perturbation result in a significant change in ENSG00000266976 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and AC079466.1 expression is quantified. Does this perturbation result in a significant change in AC079466.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1852
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ENSG00000119535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2567
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2368
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of ENSG00000164920 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of OSR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2107
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and ENSG00000172331 expression is measured. Determine whether ENSG00000172331 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and BPGM expression is measured. Determine whether BPGM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":219
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1526
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ENSG00000184384 is measured. Does this perturbation cause a significant change in ENSG00000184384 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of MAML2 is measured. Does this perturbation cause a significant change in MAML2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1770
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of ENSG00000130656. Does perturbing EGR1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of HBZ. Does perturbing EGR1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":871
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ENSG00000186185 expression is quantified. Does this perturbation result in a significant change in ENSG00000186185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and KIF18B expression is quantified. Does this perturbation result in a significant change in KIF18B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1602
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ENSG00000109099 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in PMP22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1195
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ENSG00000005187 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":925
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ENSG00000163513 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of TGFBR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2827
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ENSG00000169442. Does perturbing MAPK1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of CD52. Does perturbing MAPK1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1951
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ENSG00000196565. Does perturbing CBFA2T3 lead to a significant change in ENSG00000196565 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of HBG2. Does perturbing CBFA2T3 lead to a significant change in HBG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":311
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ENSG00000106031 expression is quantified. Does this perturbation result in a significant change in ENSG00000106031 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and HOXA13 expression is quantified. Does this perturbation result in a significant change in HOXA13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1292
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Does this perturbation cause a significant change in ENSG00000115844 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Does this perturbation cause a significant change in DLX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":820
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ENSG00000119969 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in HELLS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2155
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ENSG00000115053 is measured. Determine whether ENSG00000115053 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of NCL is measured. Determine whether NCL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2046
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ENSG00000139219. Does this perturbation cause a significant change in ENSG00000139219 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of COL2A1. Does this perturbation cause a significant change in COL2A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":754
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and ENSG00000118058 expression is quantified. Does this perturbation result in a significant change in ENSG00000118058 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and KMT2A expression is quantified. Does this perturbation result in a significant change in KMT2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1682
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ENSG00000197766 expression is measured. Determine whether ENSG00000197766 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and CFD expression is measured. Determine whether CFD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2069
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2680
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ENSG00000079102. Does this perturbation cause a significant change in ENSG00000079102 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of RUNX1T1. Does this perturbation cause a significant change in RUNX1T1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2444
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in ENSG00000153094 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in BCL2L11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":155
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1662
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2284
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor ENSG00000101076 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101076 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor HNF4A expression. Decide whether this perturbation leads to a significant alteration in HNF4A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1268
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ENSG00000005187 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ACSM3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":905
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in ENSG00000101200 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2885
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2713
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ENSG00000076356 is measured. Does this perturbation cause a significant change in ENSG00000076356 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of PLXNA2 is measured. Does this perturbation cause a significant change in PLXNA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1780
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":420
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1132
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and ENSG00000272211 expression is quantified. Does this perturbation result in a significant change in ENSG00000272211 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and RP11-347P5.1 expression is quantified. Does this perturbation result in a significant change in RP11-347P5.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1702
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor ENSG00000101200 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101200 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":262
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ENSG00000158578. Does perturbing RHOXF2BB lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ALAS2. Does perturbing RHOXF2BB lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2371
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ENSG00000149516 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000149516 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor MS4A3 expression. Decide whether this perturbation leads to a significant alteration in MS4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":998
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000144655 is measured. Determine whether ENSG00000144655 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Determine whether CSRNP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":786
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Determine whether ENSG00000196565 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Determine whether HBG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":316
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ENSG00000128016. Does this perturbation cause a significant change in ENSG00000128016 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ZFP36. Does this perturbation cause a significant change in ZFP36 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2054
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2685
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ENSG00000076356 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000076356 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor PLXNA2 expression. Decide whether this perturbation leads to a significant alteration in PLXNA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1788
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ENSG00000143401 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143401 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ANP32E expression. Decide whether this perturbation leads to a significant alteration in ANP32E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2088
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor ENSG00000105223 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105223 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor PLD3 expression. Decide whether this perturbation leads to a significant alteration in PLD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1228
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ENSG00000104894. Does perturbing COL2A1 lead to a significant change in ENSG00000104894 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of CD37. Does perturbing COL2A1 lead to a significant change in CD37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":771
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2360
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":882
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of ENSG00000125144 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of MT1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":207
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2264
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor ENSG00000172331 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000172331 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor BPGM expression. Decide whether this perturbation leads to a significant alteration in BPGM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":218
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1072
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ENSG00000102804. Does this perturbation cause a significant change in ENSG00000102804 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of TSC22D1. Does this perturbation cause a significant change in TSC22D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2914
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000196565 is measured. Does this perturbation cause a significant change in ENSG00000196565 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of HBG2 is measured. Does this perturbation cause a significant change in HBG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2390
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of ENSG00000121900 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of TMEM54 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2777
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor ENSG00000120738 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000120738 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor EGR1 expression. Decide whether this perturbation leads to a significant alteration in EGR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2668
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2519
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2597
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1980
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ENSG00000002586 is measured. Does this perturbation cause a significant change in ENSG00000002586 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of CD99 is measured. Does this perturbation cause a significant change in CD99 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":330
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and ENSG00000240065 expression is observed. Does this perturbation lead to a significant difference in ENSG00000240065 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1483
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1002
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and ENSG00000273706 expression is quantified. Does this perturbation result in a significant change in ENSG00000273706 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1712
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2217
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ENSG00000130656. Does perturbing PTPN12 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of HBZ. Does perturbing PTPN12 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2281
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ENSG00000166450 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166450 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor PRTG expression. Decide whether this perturbation leads to a significant alteration in PRTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2238
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is measured. Determine whether ENSG00000160185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2959
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Determine whether ENSG00000157557 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Determine whether ETS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":936
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ENSG00000206172 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000206172 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor HBA1 expression. Decide whether this perturbation leads to a significant alteration in HBA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2278
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of ENSG00000120738 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of EGR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2667
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and ENSG00000105223 expression is quantified. Does this perturbation result in a significant change in ENSG00000105223 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and PLD3 expression is quantified. Does this perturbation result in a significant change in PLD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1222
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2698
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and ENSG00000164687 expression is observed. Does this perturbation lead to a significant difference in ENSG00000164687 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1693
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ENSG00000106031 expression is measured. Determine whether ENSG00000106031 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and HOXA13 expression is measured. Determine whether HOXA13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1299
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is quantified. Does this perturbation result in a significant change in ENSG00000129514 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FOXA1 expression is quantified. Does this perturbation result in a significant change in FOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1022
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000254614 is measured. Determine whether ENSG00000254614 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of AP003068.23 is measured. Determine whether AP003068.23 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2616
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and ENSG00000153012 expression is quantified. Does this perturbation result in a significant change in ENSG00000153012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and LGI2 expression is quantified. Does this perturbation result in a significant change in LGI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":482
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000183770 is measured. Does this perturbation cause a significant change in ENSG00000183770 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":290
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3074
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2218
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ENSG00000170542 is measured. Determine whether ENSG00000170542 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of SERPINB9 is measured. Determine whether SERPINB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2536
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":563
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ENSG00000170689. Does this perturbation cause a significant change in ENSG00000170689 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of HOXB9. Does this perturbation cause a significant change in HOXB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1334
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2282
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1820
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENSG00000186051 expression is quantified. Does this perturbation result in a significant change in ENSG00000186051 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and TAL2 expression is quantified. Does this perturbation result in a significant change in TAL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2332
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is measured. Determine whether ENSG00000116871 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1939
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and ENSG00000123473 expression is measured. Determine whether ENSG00000123473 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and STIL expression is measured. Determine whether STIL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2749
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Determine whether ENSG00000174498 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1416
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ENSG00000213934. Does this perturbation cause a significant change in ENSG00000213934 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of HBG1. Does this perturbation cause a significant change in HBG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":324
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and ENSG00000180785 expression is quantified. Does this perturbation result in a significant change in ENSG00000180785 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and OR51E1 expression is quantified. Does this perturbation result in a significant change in OR51E1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1472
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2420
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Does this perturbation cause a significant change in ENSG00000163513 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Does this perturbation cause a significant change in TGFBR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2830
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ENSG00000143674 expression is quantified. Does this perturbation result in a significant change in ENSG00000143674 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and KIAA1804 expression is quantified. Does this perturbation result in a significant change in KIAA1804 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1562
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":260
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is quantified. Does this perturbation result in a significant change in ENSG00000070214 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and SLC44A1 expression is quantified. Does this perturbation result in a significant change in SLC44A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3012
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ENSG00000130303 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130303 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3033
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Does this perturbation cause a significant change in ENSG00000184697 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Does this perturbation cause a significant change in CLDN6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":640
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000133317 is measured. Determine whether ENSG00000133317 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of LGALS12 is measured. Determine whether LGALS12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2456
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2700
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ENSG00000143162 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143162 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CREG1 expression is observed. Does this perturbation lead to a significant difference in CREG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1593
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and ENSG00000265972 expression is measured. Determine whether ENSG00000265972 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1249
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of ENSG00000203989 is measured. Determine whether ENSG00000203989 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of RHOXF2BB is measured. Determine whether RHOXF2BB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2756
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1256
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is quantified. Does this perturbation result in a significant change in ENSG00000124762 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":372
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3118
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Does this perturbation cause a significant change in ENSG00000170689 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Does this perturbation cause a significant change in HOXB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1320
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in ENSG00000101200 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2795
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of ENSG00000069011. Does this perturbation cause a significant change in ENSG00000069011 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of PITX1. Does this perturbation cause a significant change in PITX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1214
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of ENSG00000277268 is measured. Determine whether ENSG00000277268 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of RP11-445F12.1 is measured. Determine whether RP11-445F12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1726
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in ENSG00000247516 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in MIR4458HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3065
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and ENSG00000141753 expression is measured. Determine whether ENSG00000141753 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and IGFBP4 expression is measured. Determine whether IGFBP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2969
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":352
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of ENSG00000160838 is measured. Does this perturbation cause a significant change in ENSG00000160838 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of LRRC71 is measured. Does this perturbation cause a significant change in LRRC71 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ENSG00000108984. Does this perturbation cause a significant change in ENSG00000108984 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of MAP2K6. Does this perturbation cause a significant change in MAP2K6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1834
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and ENSG00000245532 expression is measured. Determine whether ENSG00000245532 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and NEAT1 expression is measured. Determine whether NEAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":599
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ENSG00000135047. Does perturbing ZC3HAV1 lead to a significant change in ENSG00000135047 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of CTSL. Does perturbing ZC3HAV1 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3101
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ENSG00000105610 expression is measured. Determine whether ENSG00000105610 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and KLF1 expression is measured. Determine whether KLF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1679
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ENSG00000130176. Does this perturbation cause a significant change in ENSG00000130176 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CNN1. Does this perturbation cause a significant change in CNN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":674
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Does this perturbation cause a significant change in ENSG00000166450 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Does this perturbation cause a significant change in PRTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2220
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of ENSG00000154127 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2977
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ENSG00000279669. Does this perturbation cause a significant change in ENSG00000279669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of RP11-717F1.1. Does this perturbation cause a significant change in RP11-717F1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2674
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ENSG00000140545 expression is observed. Does this perturbation lead to a significant difference in ENSG00000140545 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":613
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is quantified. Does this perturbation result in a significant change in ENSG00000154127 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2982
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ENSG00000140545 expression is measured. Determine whether ENSG00000140545 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":619
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ENSG00000106546 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000106546 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor AHR expression. Decide whether this perturbation leads to a significant alteration in AHR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of ENSG00000117139. Does perturbing ZNF318 lead to a significant change in ENSG00000117139 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of KDM5B. Does perturbing ZNF318 lead to a significant change in KDM5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3141
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of ENSG00000179111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of HES7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1207
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ENSG00000148180 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in GSN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1345
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ENSG00000077063 is measured. Determine whether ENSG00000077063 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of CTTNBP2 is measured. Determine whether CTTNBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2682
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and ENSG00000198758 expression is observed. Does this perturbation lead to a significant difference in ENSG00000198758 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and EPS8L3 expression is observed. Does this perturbation lead to a significant difference in EPS8L3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1283
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ENSG00000266976. Does this perturbation cause a significant change in ENSG00000266976 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of AC079466.1. Does this perturbation cause a significant change in AC079466.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1854
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Determine whether ENSG00000164920 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Determine whether OSR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2116
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ENSG00000159556 expression is measured. Determine whether ENSG00000159556 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ISL2 expression is measured. Determine whether ISL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1509
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000184486 is measured. Determine whether ENSG00000184486 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of POU3F2 is measured. Determine whether POU3F2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2166
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ENSG00000077063. Does this perturbation cause a significant change in ENSG00000077063 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CTTNBP2. Does this perturbation cause a significant change in CTTNBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1614
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2287
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ENSG00000105939. Does this perturbation cause a significant change in ENSG00000105939 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3094
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ENSG00000120885 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of CLU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2927
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2572
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ENSG00000079102 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of RUNX1T1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2447
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is measured. Determine whether ENSG00000183770 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1119
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ENSG00000070214 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of SLC44A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3027
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and ENSG00000245532 expression is quantified. Does this perturbation result in a significant change in ENSG00000245532 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and NEAT1 expression is quantified. Does this perturbation result in a significant change in NEAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":592
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Does this perturbation cause a significant change in ENSG00000196565 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Does this perturbation cause a significant change in HBG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":300
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ENSG00000111348 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1977
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ENSG00000129757 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CDKN1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":445
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ENSG00000115053 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115053 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor NCL expression. Decide whether this perturbation leads to a significant alteration in NCL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2048
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ENSG00000002586 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000002586 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor CD99 expression. Decide whether this perturbation leads to a significant alteration in CD99 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":338
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and ENSG00000255346 expression is observed. Does this perturbation lead to a significant difference in ENSG00000255346 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and NOX5 expression is observed. Does this perturbation lead to a significant difference in NOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2893
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and ENSG00000279529 expression is observed. Does this perturbation lead to a significant difference in ENSG00000279529 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and CTD-3222D19.8 expression is observed. Does this perturbation lead to a significant difference in CTD-3222D19.8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1643
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and ENSG00000164687 expression is measured. Determine whether ENSG00000164687 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1699
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of ENSG00000159399. Does perturbing HK2 lead to a significant change in ENSG00000159399 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of HK2. Does perturbing HK2 lead to a significant change in HK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1231
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and ENSG00000237330 expression is measured. Determine whether ENSG00000237330 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and RNF223 expression is measured. Determine whether RNF223 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2409
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2590
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ENSG00000119535 expression is measured. Determine whether ENSG00000119535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2569
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ENSG00000134294 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000134294 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor SLC38A2 expression. Decide whether this perturbation leads to a significant alteration in SLC38A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2588
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ENSG00000002586 is measured. Determine whether ENSG00000002586 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of CD99 is measured. Determine whether CD99 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":336
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and ENSG00000160838 expression is measured. Determine whether ENSG00000160838 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and LRRC71 expression is measured. Determine whether LRRC71 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ENSG00000115255 expression is quantified. Does this perturbation result in a significant change in ENSG00000115255 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and REEP6 expression is quantified. Does this perturbation result in a significant change in REEP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":622
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2298
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and ENSG00000121068 expression is quantified. Does this perturbation result in a significant change in ENSG00000121068 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and TBX2 expression is quantified. Does this perturbation result in a significant change in TBX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2782
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor ENSG00000279529 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000279529 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor CTD-3222D19.8 expression. Decide whether this perturbation leads to a significant alteration in CTD-3222D19.8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1648
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":382
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of ENSG00000030110. Does perturbing BAK1 lead to a significant change in ENSG00000030110 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":131
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is measured. Determine whether ENSG00000005187 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":909
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of ENSG00000121900. Does perturbing TBX2 lead to a significant change in ENSG00000121900 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of TMEM54. Does perturbing TBX2 lead to a significant change in TMEM54 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2771
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ENSG00000231312 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AC007246.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1865
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in ENSG00000163497 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":975
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and ENSG00000168209 expression is measured. Determine whether ENSG00000168209 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and DDIT4 expression is measured. Determine whether DDIT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":739
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2696
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in ENSG00000092067 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CEBPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":525
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000156030 is measured. Determine whether ENSG00000156030 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ELMSAN1 is measured. Determine whether ELMSAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":916
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and ENSG00000169410 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169410 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PTPN9 expression is observed. Does this perturbation lead to a significant difference in PTPN9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2343
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in ENSG00000205277 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in MUC12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3135
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ENSG00000105939 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000105939 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3098
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ENSG00000144655. Does perturbing CSRNP1 lead to a significant change in ENSG00000144655 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of CSRNP1. Does perturbing CSRNP1 lead to a significant change in CSRNP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":781
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and ENSG00000026297 expression is observed. Does this perturbation lead to a significant difference in ENSG00000026297 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and RNASET2 expression is observed. Does this perturbation lead to a significant difference in RNASET2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":833
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ENSG00000113369 expression is quantified. Does this perturbation result in a significant change in ENSG00000113369 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ARRDC3 expression is quantified. Does this perturbation result in a significant change in ARRDC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ENSG00000070214 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070214 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor SLC44A1 expression. Decide whether this perturbation leads to a significant alteration in SLC44A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3028
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000140287 is measured. Does this perturbation cause a significant change in ENSG00000140287 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of HDC is measured. Does this perturbation cause a significant change in HDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2170
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000206172 is measured. Determine whether ENSG00000206172 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of HBA1 is measured. Determine whether HBA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2276
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor ENSG00000142945 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142945 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1638
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2497
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ENSG00000005187. Does perturbing ELMSAN1 lead to a significant change in ENSG00000005187 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ACSM3. Does perturbing ELMSAN1 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":901
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3072
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and ENSG00000153012 expression is quantified. Does this perturbation result in a significant change in ENSG00000153012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and LGI2 expression is quantified. Does this perturbation result in a significant change in LGI2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":492
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000113369 is measured. Determine whether ENSG00000113369 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ARRDC3 is measured. Determine whether ARRDC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of ENSG00000240065 is measured. Does this perturbation cause a significant change in ENSG00000240065 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of PSMB9 is measured. Does this perturbation cause a significant change in PSMB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1480
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of ENSG00000125144. Does perturbing BCORL1 lead to a significant change in ENSG00000125144 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of MT1G. Does perturbing BCORL1 lead to a significant change in MT1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":201
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and ENSG00000090238 expression is quantified. Does this perturbation result in a significant change in ENSG00000090238 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and YPEL3 expression is quantified. Does this perturbation result in a significant change in YPEL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1162
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":656
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and ENSG00000118058 expression is measured. Determine whether ENSG00000118058 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and KMT2A expression is measured. Determine whether KMT2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1689
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ENSG00000137841. Does perturbing PLK4 lead to a significant change in ENSG00000137841 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of PLCB2. Does perturbing PLK4 lead to a significant change in PLCB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2131
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2290
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ENSG00000077063 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of CTTNBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ENSG00000135047 expression is measured. Determine whether ENSG00000135047 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1889
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ENSG00000183770 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1127
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ENSG00000135047 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135047 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2603
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ENSG00000197766. Does perturbing NCL lead to a significant change in ENSG00000197766 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of CFD. Does perturbing NCL lead to a significant change in CFD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2061
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of ENSG00000164687 is measured. Does this perturbation cause a significant change in ENSG00000164687 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1690
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of ENSG00000164687. Does this perturbation cause a significant change in ENSG00000164687 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1694
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ENSG00000130829 expression is quantified. Does this perturbation result in a significant change in ENSG00000130829 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and DUSP9 expression is quantified. Does this perturbation result in a significant change in DUSP9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":842
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ENSG00000106546 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of AHR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ENSG00000158578. Does perturbing PRTG lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ALAS2. Does perturbing PRTG lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2241
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of ENSG00000064886. Does perturbing TP73 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of CHI3L2. Does perturbing TP73 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2901
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2379
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1870
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2707
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2382
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in ENSG00000030110 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":145
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ENSG00000184384 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184384 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor MAML2 expression. Decide whether this perturbation leads to a significant alteration in MAML2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1778
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2376
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000279576 is measured. Determine whether ENSG00000279576 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of AP000769.1 is measured. Determine whether AP000769.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1946
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of ENSG00000163499. Does perturbing FEV lead to a significant change in ENSG00000163499 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of CRYBA2. Does perturbing FEV lead to a significant change in CRYBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":981
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ENSG00000114315 expression is observed. Does this perturbation lead to a significant difference in ENSG00000114315 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and HES1 expression is observed. Does this perturbation lead to a significant difference in HES1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2033
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of ENSG00000183019. Does this perturbation cause a significant change in ENSG00000183019 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of MCEMP1. Does this perturbation cause a significant change in MCEMP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":174
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of ENSG00000179111. Does this perturbation cause a significant change in ENSG00000179111 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of HES7. Does this perturbation cause a significant change in HES7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1204
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ENSG00000130656. Does perturbing PRDM1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of HBZ. Does perturbing PRDM1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2211
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ENSG00000177606 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177606 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and JUN expression is observed. Does this perturbation lead to a significant difference in JUN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1543
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Does this perturbation cause a significant change in ENSG00000160185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2950
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Determine whether ENSG00000184697 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Determine whether CLDN6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":636
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and ENSG00000182871 expression is observed. Does this perturbation lead to a significant difference in ENSG00000182871 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and COL18A1 expression is observed. Does this perturbation lead to a significant difference in COL18A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2323
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ENSG00000184697. Does this perturbation cause a significant change in ENSG00000184697 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CLDN6. Does this perturbation cause a significant change in CLDN6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":634
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":887
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3112
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Does this perturbation cause a significant change in ENSG00000157557 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Does this perturbation cause a significant change in ETS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":930
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2904
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of ENSG00000198758 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of EPS8L3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1287
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and ENSG00000104903 expression is measured. Determine whether ENSG00000104903 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and LYL1 expression is measured. Determine whether LYL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1749
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":854
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ENSG00000144655 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000144655 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor CSRNP1 expression. Decide whether this perturbation leads to a significant alteration in CSRNP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":788
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Determine whether ENSG00000129514 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Determine whether FOXA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1026
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ENSG00000105939 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3097
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in ENSG00000117139 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in KDM5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3145
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of ENSG00000273706. Does this perturbation cause a significant change in ENSG00000273706 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1714
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ENSG00000011600. Does perturbing SPI1 lead to a significant change in ENSG00000011600 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of TYROBP. Does perturbing SPI1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2721
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor ENSG00000163497 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163497 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1738
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in ENSG00000163499 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in CRYBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":985
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ENSG00000170180 expression is measured. Determine whether ENSG00000170180 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and GYPA expression is measured. Determine whether GYPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":719
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000130303 is measured. Determine whether ENSG00000130303 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3036
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in ENSG00000125931 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in CITED1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":575
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ENSG00000189171. Does perturbing NIT1 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of S100A13. Does perturbing NIT1 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2071
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and ENSG00000163499 expression is quantified. Does this perturbation result in a significant change in ENSG00000163499 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and CRYBA2 expression is quantified. Does this perturbation result in a significant change in CRYBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":982
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1829
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of ENSG00000117091. Does this perturbation cause a significant change in ENSG00000117091 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of CD48. Does this perturbation cause a significant change in CD48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1374
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ENSG00000206172 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of HBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2277
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is quantified. Does this perturbation result in a significant change in ENSG00000103241 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1082
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000162493 is measured. Does this perturbation cause a significant change in ENSG00000162493 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PDPN is measured. Does this perturbation cause a significant change in PDPN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2620
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Does this perturbation cause a significant change in ENSG00000142945 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1630
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ENSG00000260793 expression is observed. Does this perturbation lead to a significant difference in ENSG00000260793 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP5-882C2.2 expression is observed. Does this perturbation lead to a significant difference in RP5-882C2.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2143
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2683
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ENSG00000141753. Does this perturbation cause a significant change in ENSG00000141753 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of IGFBP4. Does this perturbation cause a significant change in IGFBP4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":394
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1468
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ENSG00000120885 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in CLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2925
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of ENSG00000160838 is measured. Determine whether ENSG00000160838 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of LRRC71 is measured. Determine whether LRRC71 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor ENSG00000240065 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000240065 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor PSMB9 expression. Decide whether this perturbation leads to a significant alteration in PSMB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1488
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of ENSG00000064886. Does perturbing RREB1 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CHI3L2. Does perturbing RREB1 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2421
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of ENSG00000142945. Does perturbing KIF2C lead to a significant change in ENSG00000142945 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1631
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Determine whether ENSG00000166450 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Determine whether PRTG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2236
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000117091 is measured. Determine whether ENSG00000117091 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of CD48 is measured. Determine whether CD48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1376
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Does this perturbation cause a significant change in ENSG00000258274 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Does this perturbation cause a significant change in RP11-887P2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1350
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ENSG00000184384 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in MAML2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1775
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ENSG00000124762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":365
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1138
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and ENSG00000265972 expression is observed. Does this perturbation lead to a significant difference in ENSG00000265972 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1243
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in ENSG00000245848 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in CEBPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":555
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ENSG00000156030 expression is observed. Does this perturbation lead to a significant difference in ENSG00000156030 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ELMSAN1 expression is observed. Does this perturbation lead to a significant difference in ELMSAN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":913
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Does this perturbation cause a significant change in ENSG00000103241 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1090
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ENSG00000166450. Does this perturbation cause a significant change in ENSG00000166450 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of PRTG. Does this perturbation cause a significant change in PRTG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2234
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and ENSG00000120738 expression is quantified. Does this perturbation result in a significant change in ENSG00000120738 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and EGR1 expression is quantified. Does this perturbation result in a significant change in EGR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2662
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of ENSG00000071967. Does perturbing IRF1 lead to a significant change in ENSG00000071967 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of CYBRD1. Does perturbing IRF1 lead to a significant change in CYBRD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1491
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ENSG00000124762 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000124762 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":368
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Does this perturbation cause a significant change in ENSG00000092067 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Does this perturbation cause a significant change in CEBPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":520
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2187
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ENSG00000166450. Does perturbing PRTG lead to a significant change in ENSG00000166450 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of PRTG. Does perturbing PRTG lead to a significant change in PRTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2231
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000085185 is measured. Does this perturbation cause a significant change in ENSG00000085185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of BCORL1 is measured. Does this perturbation cause a significant change in BCORL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":180
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and ENSG00000172331 expression is quantified. Does this perturbation result in a significant change in ENSG00000172331 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and BPGM expression is quantified. Does this perturbation result in a significant change in BPGM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":212
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ENSG00000140287 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in HDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2175
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of ENSG00000247516. Does this perturbation cause a significant change in ENSG00000247516 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of MIR4458HG. Does this perturbation cause a significant change in MIR4458HG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3084
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ENSG00000177606 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of JUN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1547
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Does this perturbation cause a significant change in ENSG00000099625 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Does this perturbation cause a significant change in C19orf26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":240
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ENSG00000116871. Does this perturbation cause a significant change in ENSG00000116871 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1934
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and ENSG00000245848 expression is quantified. Does this perturbation result in a significant change in ENSG00000245848 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and CEBPA expression is quantified. Does this perturbation result in a significant change in CEBPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":552
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1663
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ENSG00000183770 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183770 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1113
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ENSG00000005187 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ACSM3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1577
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and ENSG00000258274 expression is observed. Does this perturbation lead to a significant difference in ENSG00000258274 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and RP11-887P2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-887P2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1353
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1402
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ENSG00000103241. Does perturbing FOXF1 lead to a significant change in ENSG00000103241 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1091
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ENSG00000184009 expression is quantified. Does this perturbation result in a significant change in ENSG00000184009 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ACTG1 expression is quantified. Does this perturbation result in a significant change in ACTG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2872
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and ENSG00000243449 expression is observed. Does this perturbation lead to a significant difference in ENSG00000243449 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and C4orf48 expression is observed. Does this perturbation lead to a significant difference in C4orf48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":543
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of ENSG00000129514 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1027
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of ENSG00000169410 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PTPN9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2347
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ENSG00000166501. Does perturbing SET lead to a significant change in ENSG00000166501 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of PRKCB. Does perturbing SET lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2541
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ENSG00000260793 expression is quantified. Does this perturbation result in a significant change in ENSG00000260793 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP5-882C2.2 expression is quantified. Does this perturbation result in a significant change in RP5-882C2.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2142
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is quantified. Does this perturbation result in a significant change in ENSG00000184697 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CLDN6 expression is quantified. Does this perturbation result in a significant change in CLDN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":642
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000129757 is measured. Determine whether ENSG00000129757 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CDKN1C is measured. Determine whether CDKN1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":446
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ENSG00000108984. Does perturbing MAP2K6 lead to a significant change in ENSG00000108984 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of MAP2K6. Does perturbing MAP2K6 lead to a significant change in MAP2K6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1841
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and ENSG00000125931 expression is quantified. Does this perturbation result in a significant change in ENSG00000125931 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and CITED1 expression is quantified. Does this perturbation result in a significant change in CITED1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":572
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of ENSG00000125931 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of CITED1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":577
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of ENSG00000070087 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of PFN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":507
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENSG00000182871 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in COL18A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2325
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ENSG00000113594 expression is observed. Does this perturbation lead to a significant difference in ENSG00000113594 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and LIFR expression is observed. Does this perturbation lead to a significant difference in LIFR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1793
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ENSG00000130656. Does perturbing CNN1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of HBZ. Does perturbing CNN1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":681
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":569
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ENSG00000188483 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188483 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and IER5L expression is observed. Does this perturbation lead to a significant difference in IER5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1383
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ENSG00000184384 expression is measured. Determine whether ENSG00000184384 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and MAML2 expression is measured. Determine whether MAML2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1779
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ENSG00000196565 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of HBG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":317
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":653
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":459
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Does this perturbation cause a significant change in ENSG00000079102 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Does this perturbation cause a significant change in RUNX1T1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2440
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of ENSG00000129514 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FOXA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1037
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ENSG00000111348 expression is measured. Determine whether ENSG00000111348 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1979
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of ENSG00000196517. Does perturbing SLC6A9 lead to a significant change in ENSG00000196517 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of SLC6A9. Does perturbing SLC6A9 lead to a significant change in SLC6A9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2641
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ENSG00000115738 expression is quantified. Does this perturbation result in a significant change in ENSG00000115738 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ID2 expression is quantified. Does this perturbation result in a significant change in ID2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2012
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ENSG00000158373 is measured. Does this perturbation cause a significant change in ENSG00000158373 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of HIST1H2BD is measured. Does this perturbation cause a significant change in HIST1H2BD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2090
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of ENSG00000090238. Does this perturbation cause a significant change in ENSG00000090238 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of YPEL3. Does this perturbation cause a significant change in YPEL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1164
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000188536 is measured. Does this perturbation cause a significant change in ENSG00000188536 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of HBA2 is measured. Does this perturbation cause a significant change in HBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2470
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1108
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of ENSG00000068078. Does perturbing ARID1A lead to a significant change in ENSG00000068078 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of FGFR3. Does perturbing ARID1A lead to a significant change in FGFR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ENSG00000142669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and SH3BGRL3 expression is observed. Does this perturbation lead to a significant difference in SH3BGRL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":793
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ENSG00000184697 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184697 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CLDN6 expression. Decide whether this perturbation leads to a significant alteration in CLDN6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":638
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ENSG00000158578. Does perturbing ATL1 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ALAS2. Does perturbing ATL1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ENSG00000204472. Does perturbing MAPK1 lead to a significant change in ENSG00000204472 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of AIF1. Does perturbing MAPK1 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1961
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor ENSG00000108821 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000108821 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor COL1A1 expression. Decide whether this perturbation leads to a significant alteration in COL1A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":728
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and ENSG00000180785 expression is observed. Does this perturbation lead to a significant difference in ENSG00000180785 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and OR51E1 expression is observed. Does this perturbation lead to a significant difference in OR51E1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1473
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ENSG00000184486. Does this perturbation cause a significant change in ENSG00000184486 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of POU3F2. Does this perturbation cause a significant change in POU3F2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2164
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ENSG00000260793 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP5-882C2.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2145
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2265
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of ENSG00000273706 is measured. Does this perturbation cause a significant change in ENSG00000273706 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000105939 is measured. Does this perturbation cause a significant change in ENSG00000105939 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3090
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ENSG00000005187. Does this perturbation cause a significant change in ENSG00000005187 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":924
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ENSG00000070214 expression is quantified. Does this perturbation result in a significant change in ENSG00000070214 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and SLC44A1 expression is quantified. Does this perturbation result in a significant change in SLC44A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1172
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3048
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":428
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ENSG00000169413 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in RNASE6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1915
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and ENSG00000135409 expression is quantified. Does this perturbation result in a significant change in ENSG00000135409 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":222
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and ENSG00000265972 expression is quantified. Does this perturbation result in a significant change in ENSG00000265972 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1242
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is quantified. Does this perturbation result in a significant change in ENSG00000174498 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1422
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in ENSG00000102804 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in TSC22D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":285
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ENSG00000204472 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204472 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":948
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":403
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ENSG00000114315 expression is measured. Determine whether ENSG00000114315 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and HES1 expression is measured. Determine whether HES1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2039
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ENSG00000115255 expression is measured. Determine whether ENSG00000115255 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and REEP6 expression is measured. Determine whether REEP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":629
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2188
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor ENSG00000092067 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092067 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CEBPE expression. Decide whether this perturbation leads to a significant alteration in CEBPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":528
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is measured. Determine whether ENSG00000196565 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and HBG2 expression is measured. Determine whether HBG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":309
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and ENSG00000121900 expression is quantified. Does this perturbation result in a significant change in ENSG00000121900 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and TMEM54 expression is quantified. Does this perturbation result in a significant change in TMEM54 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2762
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ENSG00000204472 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":943
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor ENSG00000111057 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000111057 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor KRT18 expression. Decide whether this perturbation leads to a significant alteration in KRT18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":198
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ENSG00000118515. Does this perturbation cause a significant change in ENSG00000118515 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of SGK1. Does this perturbation cause a significant change in SGK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2554
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ENSG00000141744. Does perturbing ISL2 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of PNMT. Does perturbing ISL2 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1511
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ENSG00000134321 is measured. Does this perturbation cause a significant change in ENSG00000134321 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RSAD2 is measured. Does this perturbation cause a significant change in RSAD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":0
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Does this perturbation cause a significant change in ENSG00000108984 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Does this perturbation cause a significant change in MAP2K6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1840
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ENSG00000174498. Does this perturbation cause a significant change in ENSG00000174498 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1414
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000170608 is measured. Does this perturbation cause a significant change in ENSG00000170608 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of FOXA3 is measured. Does this perturbation cause a significant change in FOXA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1060
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and ENSG00000115844 expression is measured. Determine whether ENSG00000115844 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and DLX2 expression is measured. Determine whether DLX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":819
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ENSG00000105939 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3095
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of ENSG00000188536 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of HBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2477
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of ENSG00000169410. Does perturbing PTPN9 lead to a significant change in ENSG00000169410 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PTPN9. Does perturbing PTPN9 lead to a significant change in PTPN9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2351
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and ENSG00000092067 expression is measured. Determine whether ENSG00000092067 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CEBPE expression is measured. Determine whether CEBPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":519
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of ENSG00000164920. Does this perturbation cause a significant change in ENSG00000164920 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of OSR2. Does this perturbation cause a significant change in OSR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2114
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ENSG00000163513. Does this perturbation cause a significant change in ENSG00000163513 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of TGFBR2. Does this perturbation cause a significant change in TGFBR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2824
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor ENSG00000119535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":468
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000206172 is measured. Does this perturbation cause a significant change in ENSG00000206172 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HBA1 is measured. Does this perturbation cause a significant change in HBA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1450
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ENSG00000141753 expression is measured. Determine whether ENSG00000141753 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and IGFBP4 expression is measured. Determine whether IGFBP4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":399
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ENSG00000111348. Does perturbing MAPK1 lead to a significant change in ENSG00000111348 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ARHGDIB. Does perturbing MAPK1 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1971
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of ENSG00000164920. Does perturbing OSR2 lead to a significant change in ENSG00000164920 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of OSR2. Does perturbing OSR2 lead to a significant change in OSR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2111
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000135047 is measured. Does this perturbation cause a significant change in ENSG00000135047 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1880
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2708
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of ENSG00000183019. Does perturbing BCL2L11 lead to a significant change in ENSG00000183019 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of MCEMP1. Does perturbing BCL2L11 lead to a significant change in MCEMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":171
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and ENSG00000070087 expression is measured. Determine whether ENSG00000070087 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and PFN2 expression is measured. Determine whether PFN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":509
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ENSG00000205542. Does perturbing TMSB4X lead to a significant change in ENSG00000205542 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TMSB4X. Does perturbing TMSB4X lead to a significant change in TMSB4X expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2851
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of ENSG00000258274. Does perturbing HOXC13 lead to a significant change in ENSG00000258274 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of RP11-887P2.5. Does perturbing HOXC13 lead to a significant change in RP11-887P2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1361
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2990
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and ENSG00000163499 expression is measured. Determine whether ENSG00000163499 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and CRYBA2 expression is measured. Determine whether CRYBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":969
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ENSG00000139219 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000139219 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor COL2A1 expression. Decide whether this perturbation leads to a significant alteration in COL2A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":768
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is measured. Determine whether ENSG00000163513 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and TGFBR2 expression is measured. Determine whether TGFBR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2829
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ENSG00000206172 expression is observed. Does this perturbation lead to a significant difference in ENSG00000206172 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HBA1 expression is observed. Does this perturbation lead to a significant difference in HBA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1453
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ENSG00000079102. Does perturbing RUNX1T1 lead to a significant change in ENSG00000079102 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of RUNX1T1. Does perturbing RUNX1T1 lead to a significant change in RUNX1T1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ENSG00000184384 expression is quantified. Does this perturbation result in a significant change in ENSG00000184384 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and MAML2 expression is quantified. Does this perturbation result in a significant change in MAML2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1772
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ENSG00000169442 expression is measured. Determine whether ENSG00000169442 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1959
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ENSG00000129757 expression is quantified. Does this perturbation result in a significant change in ENSG00000129757 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CDKN1C expression is quantified. Does this perturbation result in a significant change in CDKN1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":442
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ENSG00000143162 expression is quantified. Does this perturbation result in a significant change in ENSG00000143162 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CREG1 expression is quantified. Does this perturbation result in a significant change in CREG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1592
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and ENSG00000168209 expression is observed. Does this perturbation lead to a significant difference in ENSG00000168209 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and DDIT4 expression is observed. Does this perturbation lead to a significant difference in DDIT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":733
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ENSG00000119535. Does this perturbation cause a significant change in ENSG00000119535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2564
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Does this perturbation cause a significant change in ENSG00000121900 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Does this perturbation cause a significant change in TMEM54 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2770
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ENSG00000258274 expression is observed. Does this perturbation lead to a significant difference in ENSG00000258274 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and RP11-887P2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-887P2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1313
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in ENSG00000166340 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in TPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1155
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ENSG00000119535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2568
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ENSG00000143369 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143369 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ECM1 expression. Decide whether this perturbation leads to a significant alteration in ECM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2308
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1814
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ENSG00000129757 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129757 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CDKN1C expression. Decide whether this perturbation leads to a significant alteration in CDKN1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":418
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Does this perturbation cause a significant change in ENSG00000108984 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Does this perturbation cause a significant change in MAP2K6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1830
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of ENSG00000265972. Does this perturbation cause a significant change in ENSG00000265972 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1244
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ENSG00000166450 expression is measured. Determine whether ENSG00000166450 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and PRTG expression is measured. Determine whether PRTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2229
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000213934 is measured. Determine whether ENSG00000213934 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of HBG1 is measured. Determine whether HBG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":326
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ENSG00000158578. Does perturbing C19orf26 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ALAS2. Does perturbing C19orf26 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":261
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Does this perturbation cause a significant change in ENSG00000129514 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Does this perturbation cause a significant change in FOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1030
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of ENSG00000004939. Does this perturbation cause a significant change in ENSG00000004939 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of SLC4A1. Does this perturbation cause a significant change in SLC4A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2634
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of ENSG00000160185. Does this perturbation cause a significant change in ENSG00000160185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2954
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of ENSG00000105223 is measured. Does this perturbation cause a significant change in ENSG00000105223 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of PLD3 is measured. Does this perturbation cause a significant change in PLD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1220
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ENSG00000077063 is measured. Determine whether ENSG00000077063 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CTTNBP2 is measured. Determine whether CTTNBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1616
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of ENSG00000119535. Does perturbing CEBPA lead to a significant change in ENSG00000119535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CSF3R. Does perturbing CEBPA lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":461
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2192
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and ENSG00000184481 expression is measured. Determine whether ENSG00000184481 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and FOXO4 expression is measured. Determine whether FOXO4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1149
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1134
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ENSG00000279669. Does perturbing SNAI1 lead to a significant change in ENSG00000279669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of RP11-717F1.1. Does perturbing SNAI1 lead to a significant change in RP11-717F1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2671
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ENSG00000100097 expression is observed. Does this perturbation lead to a significant difference in ENSG00000100097 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":803
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of ENSG00000243449 is measured. Does this perturbation cause a significant change in ENSG00000243449 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of C4orf48 is measured. Does this perturbation cause a significant change in C4orf48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":540
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ENSG00000183770 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1115
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in ENSG00000120738 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in EGR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2665
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of ENSG00000104903 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of LYL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1747
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ENSG00000116871. Does perturbing MAP7D1 lead to a significant change in ENSG00000116871 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1931
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2375
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":534
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of ENSG00000277268 is measured. Does this perturbation cause a significant change in ENSG00000277268 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of RP11-445F12.1 is measured. Does this perturbation cause a significant change in RP11-445F12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1720
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000120885 is measured. Determine whether ENSG00000120885 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Determine whether CLU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2926
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1666
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3116
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Determine whether ENSG00000154127 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2986
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2268
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ENSG00000113594 is measured. Does this perturbation cause a significant change in ENSG00000113594 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of LIFR is measured. Does this perturbation cause a significant change in LIFR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1790
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ENSG00000070214. Does this perturbation cause a significant change in ENSG00000070214 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of SLC44A1. Does this perturbation cause a significant change in SLC44A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1174
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of ENSG00000143498. Does this perturbation cause a significant change in ENSG00000143498 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of TAF1A. Does this perturbation cause a significant change in TAF1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2734
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Determine whether ENSG00000183770 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1116
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ENSG00000177606 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in JUN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1585
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in ENSG00000277268 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in RP11-445F12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1725
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000109099 is measured. Does this perturbation cause a significant change in ENSG00000109099 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of PMP22 is measured. Does this perturbation cause a significant change in PMP22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1190
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in ENSG00000154127 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2985
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1466
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of ENSG00000272211 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of RP11-347P5.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1707
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ENSG00000115758. Does perturbing ARRDC3 lead to a significant change in ENSG00000115758 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ODC1. Does perturbing ARRDC3 lead to a significant change in ODC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is quantified. Does this perturbation result in a significant change in ENSG00000005187 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":922
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ENSG00000129757. Does this perturbation cause a significant change in ENSG00000129757 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CDKN1C. Does this perturbation cause a significant change in CDKN1C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":444
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ENSG00000102575 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ACP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2937
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of ENSG00000135111. Does this perturbation cause a significant change in ENSG00000135111 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of TBX3. Does this perturbation cause a significant change in TBX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2814
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and ENSG00000258274 expression is observed. Does this perturbation lead to a significant difference in ENSG00000258274 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and RP11-887P2.5 expression is observed. Does this perturbation lead to a significant difference in RP11-887P2.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1363
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ENSG00000189171 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000189171 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2078
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of ENSG00000142945 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1637
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ENSG00000070214 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in SLC44A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3025
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2513
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":864
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ENSG00000119969 expression is measured. Determine whether ENSG00000119969 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and HELLS expression is measured. Determine whether HELLS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2159
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of ENSG00000004939. Does perturbing SLC4A1 lead to a significant change in ENSG00000004939 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of SLC4A1. Does perturbing SLC4A1 lead to a significant change in SLC4A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2631
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":652
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and ENSG00000143498 expression is quantified. Does this perturbation result in a significant change in ENSG00000143498 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and TAF1A expression is quantified. Does this perturbation result in a significant change in TAF1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2732
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ENSG00000077063. Does this perturbation cause a significant change in ENSG00000077063 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of CTTNBP2. Does this perturbation cause a significant change in CTTNBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and ENSG00000004939 expression is measured. Determine whether ENSG00000004939 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and SLC4A1 expression is measured. Determine whether SLC4A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2639
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ENSG00000177606. Does perturbing JUN lead to a significant change in ENSG00000177606 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of JUN. Does perturbing JUN lead to a significant change in JUN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1541
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000070214 is measured. Determine whether ENSG00000070214 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of SLC44A1 is measured. Determine whether SLC44A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3016
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1877
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor ENSG00000092621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000092621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":748
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ENSG00000143369 expression is measured. Determine whether ENSG00000143369 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ECM1 expression is measured. Determine whether ECM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2309
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1908
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of ENSG00000118058. Does perturbing KMT2A lead to a significant change in ENSG00000118058 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of KMT2A. Does perturbing KMT2A lead to a significant change in KMT2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1681
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ENSG00000170689 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170689 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor HOXB9 expression. Decide whether this perturbation leads to a significant alteration in HOXB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1338
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Determine whether ENSG00000153012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Determine whether LGI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":486
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and ENSG00000121900 expression is observed. Does this perturbation lead to a significant difference in ENSG00000121900 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and TMEM54 expression is observed. Does this perturbation lead to a significant difference in TMEM54 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2763
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and ENSG00000135409 expression is measured. Determine whether ENSG00000135409 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":229
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of ENSG00000254614 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of AP003068.23 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2617
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of ENSG00000070087. Does perturbing CEBPB lead to a significant change in ENSG00000070087 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of PFN2. Does perturbing CEBPB lead to a significant change in PFN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":501
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ENSG00000266976 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in AC079466.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1855
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":425
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ENSG00000186185. Does this perturbation cause a significant change in ENSG00000186185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of KIF18B. Does this perturbation cause a significant change in KIF18B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1604
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in ENSG00000119535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":585
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ENSG00000090382. Does this perturbation cause a significant change in ENSG00000090382 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LYZ. Does this perturbation cause a significant change in LYZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1054
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor ENSG00000166340 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166340 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor TPP1 expression. Decide whether this perturbation leads to a significant alteration in TPP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1158
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ENSG00000188483 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188483 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor IER5L expression. Decide whether this perturbation leads to a significant alteration in IER5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1398
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000134294 is measured. Does this perturbation cause a significant change in ENSG00000134294 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Does this perturbation cause a significant change in SLC38A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2580
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ENSG00000115738 is measured. Does this perturbation cause a significant change in ENSG00000115738 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ID2 is measured. Does this perturbation cause a significant change in ID2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2010
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1074
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ENSG00000130303 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3035
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of ENSG00000245848 is measured. Determine whether ENSG00000245848 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of CEBPA is measured. Determine whether CEBPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":556
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in ENSG00000184481 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in FOXO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1145
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ENSG00000102804 expression is quantified. Does this perturbation result in a significant change in ENSG00000102804 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and TSC22D1 expression is quantified. Does this perturbation result in a significant change in TSC22D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2912
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of ENSG00000180785 is measured. Determine whether ENSG00000180785 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of OR51E1 is measured. Determine whether OR51E1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1476
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":383
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of ENSG00000105223. Does this perturbation cause a significant change in ENSG00000105223 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of PLD3. Does this perturbation cause a significant change in PLD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1224
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ENSG00000119969. Does this perturbation cause a significant change in ENSG00000119969 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of HELLS. Does this perturbation cause a significant change in HELLS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2154
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of ENSG00000030110 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":147
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2703
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Determine whether ENSG00000099625 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Determine whether C19orf26 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":246
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Does this perturbation cause a significant change in ENSG00000160185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2940
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and ENSG00000196517 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196517 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and SLC6A9 expression is observed. Does this perturbation lead to a significant difference in SLC6A9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2643
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ENSG00000184384 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of MAML2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1777
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ENSG00000108984 expression is observed. Does this perturbation lead to a significant difference in ENSG00000108984 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and MAP2K6 expression is observed. Does this perturbation lead to a significant difference in MAP2K6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1843
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ENSG00000002586 expression is quantified. Does this perturbation result in a significant change in ENSG00000002586 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and CD99 expression is quantified. Does this perturbation result in a significant change in CD99 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":332
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ENSG00000140545 expression is quantified. Does this perturbation result in a significant change in ENSG00000140545 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":612
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ENSG00000119535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2565
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and ENSG00000129757 expression is measured. Determine whether ENSG00000129757 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CDKN1C expression is measured. Determine whether CDKN1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":419
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and ENSG00000245848 expression is measured. Determine whether ENSG00000245848 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and CEBPA expression is measured. Determine whether CEBPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":559
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2502
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ENSG00000137841 is measured. Does this perturbation cause a significant change in ENSG00000137841 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of PLCB2 is measured. Does this perturbation cause a significant change in PLCB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2130
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ENSG00000103241 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1095
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ENSG00000117091 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117091 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and CD48 expression is observed. Does this perturbation lead to a significant difference in CD48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1303
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is quantified. Does this perturbation result in a significant change in ENSG00000099625 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and C19orf26 expression is quantified. Does this perturbation result in a significant change in C19orf26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":252
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ENSG00000268621. Does perturbing ZC3HAV1 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of AC006262.5. Does perturbing ZC3HAV1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3111
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Determine whether ENSG00000099625 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Determine whether C19orf26 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":256
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ENSG00000163513 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163513 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and TGFBR2 expression is observed. Does this perturbation lead to a significant difference in TGFBR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2833
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":385
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":859
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ENSG00000115758 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115758 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ODC1 expression is observed. Does this perturbation lead to a significant difference in ODC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor ENSG00000030110 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000030110 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":148
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ENSG00000170180 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in GYPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":715
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in ENSG00000183019 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in MCEMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":175
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor ENSG00000071967 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000071967 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor CYBRD1 expression. Decide whether this perturbation leads to a significant alteration in CYBRD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1498
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and ENSG00000101200 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101200 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2803
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ENSG00000070214. Does perturbing GLB1L2 lead to a significant change in ENSG00000070214 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of SLC44A1. Does perturbing GLB1L2 lead to a significant change in SLC44A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1171
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of ENSG00000118058 is measured. Does this perturbation cause a significant change in ENSG00000118058 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of KMT2A is measured. Does this perturbation cause a significant change in KMT2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1680
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ENSG00000111348 expression is quantified. Does this perturbation result in a significant change in ENSG00000111348 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1972
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1103
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in ENSG00000154127 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2975
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of ENSG00000170608. Does this perturbation cause a significant change in ENSG00000170608 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of FOXA3. Does this perturbation cause a significant change in FOXA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1064
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor ENSG00000258274 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000258274 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor RP11-887P2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-887P2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1358
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":236
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and ENSG00000196188 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196188 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CTSE expression is observed. Does this perturbation lead to a significant difference in CTSE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1273
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ENSG00000034152 expression is observed. Does this perturbation lead to a significant difference in ENSG00000034152 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and MAP2K3 expression is observed. Does this perturbation lead to a significant difference in MAP2K3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1803
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2285
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and ENSG00000120738 expression is measured. Determine whether ENSG00000120738 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and EGR1 expression is measured. Determine whether EGR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2669
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000129514 is measured. Does this perturbation cause a significant change in ENSG00000129514 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FOXA1 is measured. Does this perturbation cause a significant change in FOXA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1020
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ENSG00000163513 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163513 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor TGFBR2 expression. Decide whether this perturbation leads to a significant alteration in TGFBR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2838
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of ENSG00000153094. Does this perturbation cause a significant change in ENSG00000153094 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of BCL2L11. Does this perturbation cause a significant change in BCL2L11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":154
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Determine whether ENSG00000115844 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Determine whether DLX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":826
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of ENSG00000090382 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of LYZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1047
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ENSG00000158578. Does perturbing CDKN1B lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ALAS2. Does perturbing CDKN1B lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":401
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1408
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":850
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ENSG00000108984. Does perturbing MAP2K6 lead to a significant change in ENSG00000108984 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of MAP2K6. Does perturbing MAP2K6 lead to a significant change in MAP2K6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1831
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Determine whether ENSG00000153012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Determine whether LGI2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":496
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ENSG00000118777 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000118777 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ABCG2 expression. Decide whether this perturbation leads to a significant alteration in ABCG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3008
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of ENSG00000204472. Does perturbing ETS2 lead to a significant change in ENSG00000204472 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of AIF1. Does perturbing ETS2 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":941
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":347
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Does this perturbation cause a significant change in ENSG00000247516 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Does this perturbation cause a significant change in MIR4458HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3060
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of ENSG00000123473 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of STIL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2747
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in ENSG00000164920 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in OSR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2115
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor ENSG00000179111 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000179111 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor HES7 expression. Decide whether this perturbation leads to a significant alteration in HES7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1208
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2687
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ENSG00000134321 is measured. Determine whether ENSG00000134321 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RSAD2 is measured. Determine whether RSAD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2212
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of ENSG00000163497. Does perturbing LHX1 lead to a significant change in ENSG00000163497 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of FEV. Does perturbing LHX1 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1731
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of ENSG00000245532. Does this perturbation cause a significant change in ENSG00000245532 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of NEAT1. Does this perturbation cause a significant change in NEAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":594
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of ENSG00000180785 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of OR51E1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1477
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1822
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130829 is measured. Determine whether ENSG00000130829 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of DUSP9 is measured. Determine whether DUSP9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":846
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Determine whether ENSG00000079102 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Determine whether RUNX1T1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2436
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ENSG00000231312 expression is quantified. Does this perturbation result in a significant change in ENSG00000231312 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AC007246.3 expression is quantified. Does this perturbation result in a significant change in AC007246.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1862
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and ENSG00000090382 expression is measured. Determine whether ENSG00000090382 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and LYZ expression is measured. Determine whether LYZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1049
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1520
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ENSG00000206172 expression is quantified. Does this perturbation result in a significant change in ENSG00000206172 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HBA1 expression is quantified. Does this perturbation result in a significant change in HBA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1452
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ENSG00000069535 is measured. Determine whether ENSG00000069535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of MAOB is measured. Determine whether MAOB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1536
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and ENSG00000118058 expression is observed. Does this perturbation lead to a significant difference in ENSG00000118058 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and KMT2A expression is observed. Does this perturbation lead to a significant difference in KMT2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1683
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":862
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ENSG00000099625 expression is observed. Does this perturbation lead to a significant difference in ENSG00000099625 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and C19orf26 expression is observed. Does this perturbation lead to a significant difference in C19orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":253
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of ENSG00000227053. Does this perturbation cause a significant change in ENSG00000227053 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of RP11-395B7.4. Does this perturbation cause a significant change in RP11-395B7.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3124
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ENSG00000141753 expression is quantified. Does this perturbation result in a significant change in ENSG00000141753 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and IGFBP4 expression is quantified. Does this perturbation result in a significant change in IGFBP4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":392
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":689
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is measured. Determine whether ENSG00000184697 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CLDN6 expression is measured. Determine whether CLDN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":649
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ENSG00000166450 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in PRTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2225
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of ENSG00000245532 is measured. Determine whether ENSG00000245532 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of NEAT1 is measured. Determine whether NEAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":596
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":169
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ENSG00000120885 expression is measured. Determine whether ENSG00000120885 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and CLU expression is measured. Determine whether CLU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2929
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":239
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of ENSG00000245848. Does perturbing CELF2 lead to a significant change in ENSG00000245848 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of CEBPA. Does perturbing CELF2 lead to a significant change in CEBPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":551
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of ENSG00000105697 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of HAMP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2487
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ENSG00000103241. Does perturbing FOXF1 lead to a significant change in ENSG00000103241 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1081
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of ENSG00000188536. Does perturbing S1PR2 lead to a significant change in ENSG00000188536 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of HBA2. Does perturbing S1PR2 lead to a significant change in HBA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2471
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of ENSG00000273706 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":127
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1434
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ENSG00000204472 expression is quantified. Does this perturbation result in a significant change in ENSG00000204472 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":942
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1523
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3047
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and ENSG00000125144 expression is observed. Does this perturbation lead to a significant difference in ENSG00000125144 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and MT1G expression is observed. Does this perturbation lead to a significant difference in MT1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":203
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor ENSG00000119535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":588
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":567
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1404
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of ENSG00000279529. Does this perturbation cause a significant change in ENSG00000279529 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of CTD-3222D19.8. Does this perturbation cause a significant change in CTD-3222D19.8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1644
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ENSG00000002586 expression is observed. Does this perturbation lead to a significant difference in ENSG00000002586 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and CD99 expression is observed. Does this perturbation lead to a significant difference in CD99 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":333
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2365
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of ENSG00000121900 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of TMEM54 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2767
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000266976 is measured. Does this perturbation cause a significant change in ENSG00000266976 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of AC079466.1 is measured. Does this perturbation cause a significant change in AC079466.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1850
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000120738 is measured. Determine whether ENSG00000120738 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of EGR1 is measured. Determine whether EGR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2666
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2422
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is measured. Determine whether ENSG00000139219 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and COL2A1 expression is measured. Determine whether COL2A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":759
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ENSG00000196565 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196565 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and HBG2 expression is observed. Does this perturbation lead to a significant difference in HBG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":313
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of ENSG00000204482. Does perturbing CELF2 lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of LST1. Does perturbing CELF2 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":561
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ENSG00000105610 expression is quantified. Does this perturbation result in a significant change in ENSG00000105610 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and KLF1 expression is quantified. Does this perturbation result in a significant change in KLF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1672
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ENSG00000143674 expression is measured. Determine whether ENSG00000143674 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and KIAA1804 expression is measured. Determine whether KIAA1804 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1569
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and ENSG00000121900 expression is observed. Does this perturbation lead to a significant difference in ENSG00000121900 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and TMEM54 expression is observed. Does this perturbation lead to a significant difference in TMEM54 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2773
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of ENSG00000123473 is measured. Determine whether ENSG00000123473 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of STIL is measured. Determine whether STIL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2746
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":654
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":682
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and ENSG00000188536 expression is quantified. Does this perturbation result in a significant change in ENSG00000188536 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HBA2 expression is quantified. Does this perturbation result in a significant change in HBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1442
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in ENSG00000188536 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in HBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2475
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ENSG00000174498 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1425
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ENSG00000130829. Does this perturbation cause a significant change in ENSG00000130829 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of DUSP9. Does this perturbation cause a significant change in DUSP9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":844
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ENSG00000188483 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of IER5L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1397
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of ENSG00000115844 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of DLX2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":817
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":269
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":880
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and ENSG00000123473 expression is observed. Does this perturbation lead to a significant difference in ENSG00000123473 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and STIL expression is observed. Does this perturbation lead to a significant difference in STIL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2743
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2009
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2598
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of ENSG00000163497 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":977
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ENSG00000183770 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183770 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1118
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2659
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and ENSG00000141753 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141753 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and IGFBP4 expression is observed. Does this perturbation lead to a significant difference in IGFBP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":393
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and ENSG00000110492 expression is quantified. Does this perturbation result in a significant change in ENSG00000110492 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and MDK expression is quantified. Does this perturbation result in a significant change in MDK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2202
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ENSG00000135047 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135047 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2608
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1518
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of ENSG00000026297. Does perturbing DLX2 lead to a significant change in ENSG00000026297 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of RNASET2. Does perturbing DLX2 lead to a significant change in RNASET2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":831
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ENSG00000102804. Does perturbing C3orf72 lead to a significant change in ENSG00000102804 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of TSC22D1. Does perturbing C3orf72 lead to a significant change in TSC22D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":281
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ENSG00000206172 expression is measured. Determine whether ENSG00000206172 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HBA1 expression is measured. Determine whether HBA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1459
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and ENSG00000170608 expression is quantified. Does this perturbation result in a significant change in ENSG00000170608 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and FOXA3 expression is quantified. Does this perturbation result in a significant change in FOXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1062
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000135047 is measured. Determine whether ENSG00000135047 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2606
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of ENSG00000026297 is measured. Does this perturbation cause a significant change in ENSG00000026297 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of RNASET2 is measured. Does this perturbation cause a significant change in RNASET2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":830
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":869
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ENSG00000196565. Does perturbing CBFA2T3 lead to a significant change in ENSG00000196565 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of HBG2. Does perturbing CBFA2T3 lead to a significant change in HBG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":301
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ENSG00000102804 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000102804 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor TSC22D1 expression. Decide whether this perturbation leads to a significant alteration in TSC22D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2918
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and ENSG00000069011 expression is quantified. Does this perturbation result in a significant change in ENSG00000069011 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and PITX1 expression is quantified. Does this perturbation result in a significant change in PITX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1212
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ENSG00000011600 expression is observed. Does this perturbation lead to a significant difference in ENSG00000011600 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2723
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ENSG00000186185 is measured. Does this perturbation cause a significant change in ENSG00000186185 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of KIF18B is measured. Does this perturbation cause a significant change in KIF18B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1600
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and ENSG00000125931 expression is observed. Does this perturbation lead to a significant difference in ENSG00000125931 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and CITED1 expression is observed. Does this perturbation lead to a significant difference in CITED1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":573
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ENSG00000103241 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1085
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3117
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and ENSG00000115844 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115844 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and DLX2 expression is observed. Does this perturbation lead to a significant difference in DLX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":823
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ENSG00000111348 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000111348 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1978
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and ENSG00000071967 expression is observed. Does this perturbation lead to a significant difference in ENSG00000071967 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and CYBRD1 expression is observed. Does this perturbation lead to a significant difference in CYBRD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1493
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of ENSG00000197965 is measured. Determine whether ENSG00000197965 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of MPZL1 is measured. Determine whether MPZL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2126
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and ENSG00000115844 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115844 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and DLX2 expression is observed. Does this perturbation lead to a significant difference in DLX2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":813
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of ENSG00000247516 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of MIR4458HG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3087
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ENSG00000140287 expression is quantified. Does this perturbation result in a significant change in ENSG00000140287 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and HDC expression is quantified. Does this perturbation result in a significant change in HDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2172
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of ENSG00000273706 is measured. Determine whether ENSG00000273706 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1716
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor ENSG00000121900 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000121900 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor TMEM54 expression. Decide whether this perturbation leads to a significant alteration in TMEM54 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2778
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2655
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENSG00000182871 expression is measured. Determine whether ENSG00000182871 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and COL18A1 expression is measured. Determine whether COL18A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2329
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ENSG00000115053 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115053 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and NCL expression is observed. Does this perturbation lead to a significant difference in NCL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2043
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of ENSG00000243449 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of C4orf48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":547
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of ENSG00000135409 is measured. Determine whether ENSG00000135409 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":226
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of ENSG00000279529 is measured. Does this perturbation cause a significant change in ENSG00000279529 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of CTD-3222D19.8 is measured. Does this perturbation cause a significant change in CTD-3222D19.8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1640
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ENSG00000142669. Does perturbing FOSB lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of SH3BGRL3. Does perturbing FOSB lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1011
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":568
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ENSG00000106031 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000106031 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor HOXA13 expression. Decide whether this perturbation leads to a significant alteration in HOXA13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1298
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":657
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ENSG00000144655. Does this perturbation cause a significant change in ENSG00000144655 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of CSRNP1. Does this perturbation cause a significant change in CSRNP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":784
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of ENSG00000030110. Does perturbing BAK1 lead to a significant change in ENSG00000030110 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":141
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor ENSG00000254614 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000254614 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor AP003068.23 expression. Decide whether this perturbation leads to a significant alteration in AP003068.23 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2618
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and ENSG00000030110 expression is measured. Determine whether ENSG00000030110 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":149
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of ENSG00000141753 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of IGFBP4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2967
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor ENSG00000125931 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000125931 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor CITED1 expression. Decide whether this perturbation leads to a significant alteration in CITED1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":578
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENSG00000106991. Does this perturbation cause a significant change in ENSG00000106991 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENG. Does this perturbation cause a significant change in ENG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2314
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of ENSG00000180785. Does this perturbation cause a significant change in ENSG00000180785 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of OR51E1. Does this perturbation cause a significant change in OR51E1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1474
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in ENSG00000258274 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in RP11-887P2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1355
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Determine whether ENSG00000188483 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Determine whether IER5L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1396
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of ENSG00000135111 is measured. Does this perturbation cause a significant change in ENSG00000135111 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of TBX3 is measured. Does this perturbation cause a significant change in TBX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2810
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of ENSG00000026297 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of RNASET2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":837
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of ENSG00000237330. Does this perturbation cause a significant change in ENSG00000237330 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of RNF223. Does this perturbation cause a significant change in RNF223 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2404
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ENSG00000100097. Does perturbing CSRNP1 lead to a significant change in ENSG00000100097 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LGALS1. Does perturbing CSRNP1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":801
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000227053 is measured. Does this perturbation cause a significant change in ENSG00000227053 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of RP11-395B7.4 is measured. Does this perturbation cause a significant change in RP11-395B7.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3120
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Determine whether ENSG00000163513 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2826
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ENSG00000005187. Does perturbing KIAA1804 lead to a significant change in ENSG00000005187 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ACSM3. Does perturbing KIAA1804 lead to a significant change in ACSM3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1571
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and ENSG00000121068 expression is measured. Determine whether ENSG00000121068 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and TBX2 expression is measured. Determine whether TBX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2789
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ENSG00000158373 expression is quantified. Does this perturbation result in a significant change in ENSG00000158373 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and HIST1H2BD expression is quantified. Does this perturbation result in a significant change in HIST1H2BD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2092
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":265
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ENSG00000130176 expression is measured. Determine whether ENSG00000130176 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CNN1 expression is measured. Determine whether CNN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":669
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of ENSG00000115844. Does perturbing DLX2 lead to a significant change in ENSG00000115844 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of DLX2. Does perturbing DLX2 lead to a significant change in DLX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":821
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ENSG00000169413. Does perturbing MAP4K5 lead to a significant change in ENSG00000169413 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of RNASE6. Does perturbing MAP4K5 lead to a significant change in RNASE6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1911
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of ENSG00000101200 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2887
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ENSG00000077063 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CTTNBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1615
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and ENSG00000188536 expression is measured. Determine whether ENSG00000188536 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HBA2 expression is measured. Determine whether HBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1449
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of ENSG00000247516. Does this perturbation cause a significant change in ENSG00000247516 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of MIR4458HG. Does this perturbation cause a significant change in MIR4458HG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3064
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ENSG00000260793 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP5-882C2.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2147
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1664
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":267
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of ENSG00000070087 is measured. Determine whether ENSG00000070087 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of PFN2 is measured. Determine whether PFN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":506
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ENSG00000105610. Does perturbing KLF1 lead to a significant change in ENSG00000105610 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of KLF1. Does perturbing KLF1 lead to a significant change in KLF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1671
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2259
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is measured. Determine whether ENSG00000247516 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3069
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ENSG00000113369 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ARRDC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2903
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2719
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ENSG00000115738 expression is measured. Determine whether ENSG00000115738 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ID2 expression is measured. Determine whether ID2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2019
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000085185 is measured. Determine whether ENSG00000085185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of BCORL1 is measured. Determine whether BCORL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":186
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in ENSG00000141753 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in IGFBP4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2965
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in ENSG00000118058 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in KMT2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1685
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ENSG00000139219 expression is quantified. Does this perturbation result in a significant change in ENSG00000139219 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and COL2A1 expression is quantified. Does this perturbation result in a significant change in COL2A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":762
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ENSG00000163513. Does this perturbation cause a significant change in ENSG00000163513 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of TGFBR2. Does this perturbation cause a significant change in TGFBR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2834
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3040
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ENSG00000268621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2595
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ENSG00000069535 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069535 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor MAOB expression. Decide whether this perturbation leads to a significant alteration in MAOB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1538
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of ENSG00000101200. Does perturbing TP73 lead to a significant change in ENSG00000101200 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of AVP. Does perturbing TP73 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2881
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2247
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and ENSG00000196188 expression is measured. Determine whether ENSG00000196188 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CTSE expression is measured. Determine whether CTSE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1279
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and ENSG00000164687 expression is quantified. Does this perturbation result in a significant change in ENSG00000164687 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1692
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ENSG00000184697 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184697 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CLDN6 expression is observed. Does this perturbation lead to a significant difference in CLDN6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":633
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ENSG00000135047 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3107
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":456
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor ENSG00000154127 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000154127 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2978
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ENSG00000183770 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183770 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":293
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and ENSG00000101076 expression is measured. Determine whether ENSG00000101076 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and HNF4A expression is measured. Determine whether HNF4A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1269
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2652
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in ENSG00000160185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2945
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of ENSG00000119535 is measured. Determine whether ENSG00000119535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":586
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":899
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":860
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ENSG00000119969 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000119969 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor HELLS expression. Decide whether this perturbation leads to a significant alteration in HELLS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2158
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of ENSG00000092067. Does this perturbation cause a significant change in ENSG00000092067 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CEBPE. Does this perturbation cause a significant change in CEBPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":524
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of ENSG00000163497 is measured. Does this perturbation cause a significant change in ENSG00000163497 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1730
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and ENSG00000030110 expression is observed. Does this perturbation lead to a significant difference in ENSG00000030110 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":133
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ENSG00000130829. Does perturbing DUSP9 lead to a significant change in ENSG00000130829 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of DUSP9. Does perturbing DUSP9 lead to a significant change in DUSP9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":841
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor ENSG00000090238 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000090238 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor YPEL3 expression. Decide whether this perturbation leads to a significant alteration in YPEL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1168
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000120885 is measured. Does this perturbation cause a significant change in ENSG00000120885 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Does this perturbation cause a significant change in CLU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2920
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of ENSG00000206172 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of HBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2467
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor ENSG00000196517 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196517 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor SLC6A9 expression. Decide whether this perturbation leads to a significant alteration in SLC6A9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2648
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000111057 is measured. Does this perturbation cause a significant change in ENSG00000111057 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of KRT18 is measured. Does this perturbation cause a significant change in KRT18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":190
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Determine whether ENSG00000154127 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2976
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of ENSG00000092067. Does perturbing CEBPE lead to a significant change in ENSG00000092067 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CEBPE. Does perturbing CEBPE lead to a significant change in CEBPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":521
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ENSG00000130303. Does this perturbation cause a significant change in ENSG00000130303 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3034
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000205542 is measured. Does this perturbation cause a significant change in ENSG00000205542 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TMSB4X is measured. Does this perturbation cause a significant change in TMSB4X expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2850
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ENSG00000158578. Does perturbing PRDM1 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ALAS2. Does perturbing PRDM1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2191
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ENSG00000075624 expression is observed. Does this perturbation lead to a significant difference in ENSG00000075624 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ACTB expression is observed. Does this perturbation lead to a significant difference in ACTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2863
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is measured. Determine whether ENSG00000005187 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":929
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ENSG00000076356 expression is measured. Determine whether ENSG00000076356 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and PLXNA2 expression is measured. Determine whether PLXNA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1789
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Does this perturbation cause a significant change in ENSG00000130176 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Does this perturbation cause a significant change in CNN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":660
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ENSG00000113369. Does this perturbation cause a significant change in ENSG00000113369 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ARRDC3. Does this perturbation cause a significant change in ARRDC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ENSG00000231312 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AC007246.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1867
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of ENSG00000196517. Does this perturbation cause a significant change in ENSG00000196517 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of SLC6A9. Does this perturbation cause a significant change in SLC6A9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2644
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ENSG00000034152. Does this perturbation cause a significant change in ENSG00000034152 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of MAP2K3. Does this perturbation cause a significant change in MAP2K3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1804
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Does this perturbation cause a significant change in ENSG00000163499 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Does this perturbation cause a significant change in CRYBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":980
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor ENSG00000160185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000160185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2948
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and ENSG00000153012 expression is observed. Does this perturbation lead to a significant difference in ENSG00000153012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and LGI2 expression is observed. Does this perturbation lead to a significant difference in LGI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":483
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of ENSG00000273706. Does perturbing LHX1 lead to a significant change in ENSG00000273706 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of LHX1. Does perturbing LHX1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1711
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and ENSG00000092067 expression is quantified. Does this perturbation result in a significant change in ENSG00000092067 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CEBPE expression is quantified. Does this perturbation result in a significant change in CEBPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":512
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ENSG00000134321 expression is measured. Determine whether ENSG00000134321 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RSAD2 expression is measured. Determine whether RSAD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of ENSG00000158517 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of NCF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":477
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ENSG00000137841. Does this perturbation cause a significant change in ENSG00000137841 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PLCB2. Does this perturbation cause a significant change in PLCB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2134
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor ENSG00000245532 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000245532 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor NEAT1 expression. Decide whether this perturbation leads to a significant alteration in NEAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":598
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and ENSG00000141744 expression is measured. Determine whether ENSG00000141744 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1519
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of ENSG00000163499 is measured. Does this perturbation cause a significant change in ENSG00000163499 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of CRYBA2 is measured. Does this perturbation cause a significant change in CRYBA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":960
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2494
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ENSG00000102804 expression is quantified. Does this perturbation result in a significant change in ENSG00000102804 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and TSC22D1 expression is quantified. Does this perturbation result in a significant change in TSC22D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":282
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ENSG00000168140 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of VASN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2027
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000106031 is measured. Does this perturbation cause a significant change in ENSG00000106031 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of HOXA13 is measured. Does this perturbation cause a significant change in HOXA13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1290
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ENSG00000135047. Does this perturbation cause a significant change in ENSG00000135047 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3104
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ENSG00000140287. Does perturbing POU3F2 lead to a significant change in ENSG00000140287 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of HDC. Does perturbing POU3F2 lead to a significant change in HDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2171
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ENSG00000106546. Does this perturbation cause a significant change in ENSG00000106546 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of AHR. Does this perturbation cause a significant change in AHR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":163
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ENSG00000119969. Does perturbing PLK4 lead to a significant change in ENSG00000119969 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of HELLS. Does perturbing PLK4 lead to a significant change in HELLS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2151
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ENSG00000011600 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2727
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ENSG00000114315 is measured. Does this perturbation cause a significant change in ENSG00000114315 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of HES1 is measured. Does this perturbation cause a significant change in HES1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2030
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000108984 is measured. Determine whether ENSG00000108984 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of MAP2K6 is measured. Determine whether MAP2K6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1836
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2256
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ENSG00000117091 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in CD48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1305
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ENSG00000106546 is measured. Does this perturbation cause a significant change in ENSG00000106546 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of AHR is measured. Does this perturbation cause a significant change in AHR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2509
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ENSG00000075624 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ACTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2865
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":278
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ENSG00000196565 expression is quantified. Does this perturbation result in a significant change in ENSG00000196565 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and HBG2 expression is quantified. Does this perturbation result in a significant change in HBG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2392
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1003
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ENSG00000213934 expression is measured. Determine whether ENSG00000213934 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and HBG1 expression is measured. Determine whether HBG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":329
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000174498 is measured. Does this perturbation cause a significant change in ENSG00000174498 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1420
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Determine whether ENSG00000247516 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Determine whether MIR4458HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3086
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ENSG00000149516 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of MS4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":997
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ENSG00000196565. Does perturbing RHOXF2BB lead to a significant change in ENSG00000196565 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of HBG2. Does perturbing RHOXF2BB lead to a significant change in HBG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2391
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ENSG00000005187 expression is observed. Does this perturbation lead to a significant difference in ENSG00000005187 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":903
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and ENSG00000160185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000160185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2953
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000231312 is measured. Does this perturbation cause a significant change in ENSG00000231312 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Does this perturbation cause a significant change in AC007246.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1860
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ENSG00000079102 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000079102 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor RUNX1T1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1T1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2438
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in ENSG00000068078 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in FGFR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is measured. Determine whether ENSG00000070214 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and SLC44A1 expression is measured. Determine whether SLC44A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3019
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ENSG00000115758. Does this perturbation cause a significant change in ENSG00000115758 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ODC1. Does this perturbation cause a significant change in ODC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2997
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ENSG00000184486 expression is measured. Determine whether ENSG00000184486 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and POU3F2 expression is measured. Determine whether POU3F2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2169
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and ENSG00000108821 expression is measured. Determine whether ENSG00000108821 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and COL1A1 expression is measured. Determine whether COL1A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":729
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000184009 is measured. Determine whether ENSG00000184009 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of ACTG1 is measured. Determine whether ACTG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2876
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000117139 is measured. Determine whether ENSG00000117139 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of KDM5B is measured. Determine whether KDM5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3146
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ENSG00000119535 is measured. Does this perturbation cause a significant change in ENSG00000119535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2560
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ENSG00000144655 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of CSRNP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":787
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ENSG00000119535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2563
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in ENSG00000090382 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in LYZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1045
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ENSG00000183770 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1125
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of ENSG00000160185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2957
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000168209 is measured. Determine whether ENSG00000168209 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of DDIT4 is measured. Determine whether DDIT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":736
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1823
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ENSG00000108984 expression is observed. Does this perturbation lead to a significant difference in ENSG00000108984 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and MAP2K6 expression is observed. Does this perturbation lead to a significant difference in MAP2K6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1833
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ENSG00000106031 expression is observed. Does this perturbation lead to a significant difference in ENSG00000106031 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and HOXA13 expression is observed. Does this perturbation lead to a significant difference in HOXA13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1293
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ENSG00000231312 expression is observed. Does this perturbation lead to a significant difference in ENSG00000231312 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AC007246.3 expression is observed. Does this perturbation lead to a significant difference in AC007246.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1863
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2000
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ENSG00000102804 expression is measured. Determine whether ENSG00000102804 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and TSC22D1 expression is measured. Determine whether TSC22D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2919
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of ENSG00000163497. Does this perturbation cause a significant change in ENSG00000163497 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":974
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ENSG00000139219. Does this perturbation cause a significant change in ENSG00000139219 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of COL2A1. Does this perturbation cause a significant change in COL2A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":764
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":683
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2706
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of ENSG00000121068. Does perturbing TBX2 lead to a significant change in ENSG00000121068 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of TBX2. Does perturbing TBX2 lead to a significant change in TBX2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2781
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ENSG00000234965 is measured. Does this perturbation cause a significant change in ENSG00000234965 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of SHISA8 is measured. Does this perturbation cause a significant change in SHISA8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2520
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000141753 is measured. Determine whether ENSG00000141753 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of IGFBP4 is measured. Determine whether IGFBP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":396
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ENSG00000170180 expression is quantified. Does this perturbation result in a significant change in ENSG00000170180 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and GYPA expression is quantified. Does this perturbation result in a significant change in GYPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":712
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3042
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is measured. Determine whether ENSG00000169410 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PTPN9 expression is measured. Determine whether PTPN9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2359
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of ENSG00000205277 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of MUC12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3137
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ENSG00000117091 expression is measured. Determine whether ENSG00000117091 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and CD48 expression is measured. Determine whether CD48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1309
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of ENSG00000196188 is measured. Determine whether ENSG00000196188 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CTSE is measured. Determine whether CTSE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1276
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ENSG00000158578. Does perturbing C3orf72 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of ALAS2. Does perturbing C3orf72 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":271
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":162
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":856
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of ENSG00000172331. Does this perturbation cause a significant change in ENSG00000172331 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of BPGM. Does this perturbation cause a significant change in BPGM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":214
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and ENSG00000163497 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163497 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1733
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in ENSG00000026297 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in RNASET2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":835
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1432
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ENSG00000166450. Does perturbing PRTG lead to a significant change in ENSG00000166450 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of PRTG. Does perturbing PRTG lead to a significant change in PRTG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2221
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in ENSG00000172331 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in BPGM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":215
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1879
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2498
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor ENSG00000188483 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000188483 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor IER5L expression. Decide whether this perturbation leads to a significant alteration in IER5L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1388
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":234
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ENSG00000070214. Does this perturbation cause a significant change in ENSG00000070214 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of SLC44A1. Does this perturbation cause a significant change in SLC44A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3024
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1902
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ENSG00000206172 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in HBA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2275
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000124762 is measured. Determine whether ENSG00000124762 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CDKN1A is measured. Determine whether CDKN1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":376
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Does this perturbation cause a significant change in ENSG00000116871 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1930
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor ENSG00000164920 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000164920 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor OSR2 expression. Decide whether this perturbation leads to a significant alteration in OSR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2108
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ENSG00000124762 expression is observed. Does this perturbation lead to a significant difference in ENSG00000124762 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":373
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ENSG00000099625 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in C19orf26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":255
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor ENSG00000198758 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000198758 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor EPS8L3 expression. Decide whether this perturbation leads to a significant alteration in EPS8L3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1288
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Determine whether ENSG00000160185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2946
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ENSG00000011600 expression is measured. Determine whether ENSG00000011600 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2729
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Does this perturbation cause a significant change in ENSG00000005187 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":920
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ENSG00000183770 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1117
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":357
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3079
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ENSG00000204482. Does perturbing SPI1 lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of LST1. Does perturbing SPI1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2711
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and ENSG00000203989 expression is quantified. Does this perturbation result in a significant change in ENSG00000203989 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and RHOXF2BB expression is quantified. Does this perturbation result in a significant change in RHOXF2BB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2752
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ENSG00000034152. Does perturbing MAP2K3 lead to a significant change in ENSG00000034152 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of MAP2K3. Does perturbing MAP2K3 lead to a significant change in MAP2K3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1801
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ENSG00000204472 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204472 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1968
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ENSG00000184697 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CLDN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":637
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of ENSG00000123473 is measured. Does this perturbation cause a significant change in ENSG00000123473 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of STIL is measured. Does this perturbation cause a significant change in STIL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2740
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ENSG00000159388 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159388 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1553
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ENSG00000188483 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in IER5L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1385
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor ENSG00000123473 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000123473 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor STIL expression. Decide whether this perturbation leads to a significant alteration in STIL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2748
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2384
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ENSG00000130829 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in DUSP9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":845
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ENSG00000268621. Does perturbing SGK1 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of AC006262.5. Does perturbing SGK1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2571
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ENSG00000187997 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in C17orf99 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":435
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2292
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ENSG00000115738 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115738 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ID2 expression. Decide whether this perturbation leads to a significant alteration in ID2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2018
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and ENSG00000183770 expression is quantified. Does this perturbation result in a significant change in ENSG00000183770 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":292
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ENSG00000170180. Does perturbing CNNM4 lead to a significant change in ENSG00000170180 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of GYPA. Does perturbing CNNM4 lead to a significant change in GYPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":711
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1826
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of ENSG00000110492. Does perturbing PRDM1 lead to a significant change in ENSG00000110492 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of MDK. Does perturbing PRDM1 lead to a significant change in MDK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2201
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2388
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":868
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":346
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and ENSG00000120885 expression is quantified. Does this perturbation result in a significant change in ENSG00000120885 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and CLU expression is quantified. Does this perturbation result in a significant change in CLU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2922
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ENSG00000103241 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1087
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of ENSG00000069011 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of PITX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1217
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1894
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000090382 is measured. Does this perturbation cause a significant change in ENSG00000090382 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LYZ is measured. Does this perturbation cause a significant change in LYZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1050
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ENSG00000166450 expression is measured. Determine whether ENSG00000166450 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and PRTG expression is measured. Determine whether PRTG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2239
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ENSG00000140287 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000140287 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor HDC expression. Decide whether this perturbation leads to a significant alteration in HDC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2178
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000160185 is measured. Determine whether ENSG00000160185 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2956
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and ENSG00000121900 expression is quantified. Does this perturbation result in a significant change in ENSG00000121900 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and TMEM54 expression is quantified. Does this perturbation result in a significant change in TMEM54 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2772
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ENSG00000118777 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of ABCG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3007
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor ENSG00000068078 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000068078 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor FGFR3 expression. Decide whether this perturbation leads to a significant alteration in FGFR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1004
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Determine whether ENSG00000116871 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1936
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ENSG00000143401. Does this perturbation cause a significant change in ENSG00000143401 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ANP32E. Does this perturbation cause a significant change in ANP32E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2084
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ENSG00000133317 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000133317 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor LGALS12 expression. Decide whether this perturbation leads to a significant alteration in LGALS12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2458
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3110
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1655
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ENSG00000184009 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184009 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ACTG1 expression is observed. Does this perturbation lead to a significant difference in ACTG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2873
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ENSG00000076356 expression is observed. Does this perturbation lead to a significant difference in ENSG00000076356 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and PLXNA2 expression is observed. Does this perturbation lead to a significant difference in PLXNA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1783
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in ENSG00000124762 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CDKN1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":375
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of ENSG00000141753. Does perturbing UBASH3A lead to a significant change in ENSG00000141753 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of IGFBP4. Does perturbing UBASH3A lead to a significant change in IGFBP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2961
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ENSG00000115255 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115255 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and REEP6 expression is observed. Does this perturbation lead to a significant difference in REEP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":623
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Determine whether ENSG00000183770 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1126
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ENSG00000135047 expression is quantified. Does this perturbation result in a significant change in ENSG00000135047 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1882
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and ENSG00000085185 expression is measured. Determine whether ENSG00000085185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and BCORL1 expression is measured. Determine whether BCORL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":189
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ENSG00000134321 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RSAD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":230
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":658
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ENSG00000157557 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000157557 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ETS2 expression. Decide whether this perturbation leads to a significant alteration in ETS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":938
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1990
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ENSG00000079102 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in RUNX1T1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2435
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of ENSG00000168209 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of DDIT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":737
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of ENSG00000258274 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of RP11-887P2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1367
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ENSG00000119535 expression is quantified. Does this perturbation result in a significant change in ENSG00000119535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2562
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":164
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ENSG00000034152 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000034152 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor MAP2K3 expression. Decide whether this perturbation leads to a significant alteration in MAP2K3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1808
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000158869 is measured. Determine whether ENSG00000158869 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3056
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1252
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ENSG00000076356. Does this perturbation cause a significant change in ENSG00000076356 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of PLXNA2. Does this perturbation cause a significant change in PLXNA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1784
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of ENSG00000163531 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of NFASC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1767
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":798
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ENSG00000169413 expression is measured. Determine whether ENSG00000169413 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and RNASE6 expression is measured. Determine whether RNASE6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1919
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in ENSG00000279529 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in CTD-3222D19.8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1645
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of ENSG00000069011 is measured. Does this perturbation cause a significant change in ENSG00000069011 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of PITX1 is measured. Does this perturbation cause a significant change in PITX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1210
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1657
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":853
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of ENSG00000101200. Does perturbing TBX3 lead to a significant change in ENSG00000101200 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of AVP. Does perturbing TBX3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2791
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of ENSG00000101200 is measured. Determine whether ENSG00000101200 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2886
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of ENSG00000105223 is measured. Determine whether ENSG00000105223 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of PLD3 is measured. Determine whether PLD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1226
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ENSG00000130656. Does perturbing DUSP9 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of HBZ. Does perturbing DUSP9 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":861
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2658
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ENSG00000124762. Does this perturbation cause a significant change in ENSG00000124762 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":364
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in ENSG00000142945 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1635
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000204472 is measured. Does this perturbation cause a significant change in ENSG00000204472 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1960
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2495
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and ENSG00000069482 expression is quantified. Does this perturbation result in a significant change in ENSG00000069482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and GAL expression is quantified. Does this perturbation result in a significant change in GAL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":892
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ENSG00000129757. Does perturbing CDKN1C lead to a significant change in ENSG00000129757 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CDKN1C. Does perturbing CDKN1C lead to a significant change in CDKN1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1892
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ENSG00000159388 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1555
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":692
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3044
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of ENSG00000164920. Does perturbing OSR2 lead to a significant change in ENSG00000164920 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of OSR2. Does perturbing OSR2 lead to a significant change in OSR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2101
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of ENSG00000117091 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of CD48 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1377
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and ENSG00000255346 expression is quantified. Does this perturbation result in a significant change in ENSG00000255346 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and NOX5 expression is quantified. Does this perturbation result in a significant change in NOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2892
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1105
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and ENSG00000188536 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188536 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HBA2 expression is observed. Does this perturbation lead to a significant difference in HBA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1443
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ENSG00000196565 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196565 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor HBG2 expression. Decide whether this perturbation leads to a significant alteration in HBG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2398
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of ENSG00000185198. Does perturbing MEIS1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1991
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of ENSG00000243449 is measured. Determine whether ENSG00000243449 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of C4orf48 is measured. Determine whether C4orf48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":546
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and ENSG00000272211 expression is measured. Determine whether ENSG00000272211 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and RP11-347P5.1 expression is measured. Determine whether RP11-347P5.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1709
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in ENSG00000117091 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in CD48 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1375
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":896
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of ENSG00000163513 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of TGFBR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2837
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ENSG00000256713 expression is measured. Determine whether ENSG00000256713 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PGA5 expression is measured. Determine whether PGA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":709
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":879
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Does this perturbation cause a significant change in ENSG00000169410 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Does this perturbation cause a significant change in PTPN9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2340
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ENSG00000197766 expression is observed. Does this perturbation lead to a significant difference in ENSG00000197766 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and CFD expression is observed. Does this perturbation lead to a significant difference in CFD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2063
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ENSG00000186185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of KIF18B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1607
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor ENSG00000170608 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170608 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor FOXA3 expression. Decide whether this perturbation leads to a significant alteration in FOXA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1068
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":694
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of ENSG00000069482. Does this perturbation cause a significant change in ENSG00000069482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of GAL. Does this perturbation cause a significant change in GAL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":894
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ENSG00000197766 expression is quantified. Does this perturbation result in a significant change in ENSG00000197766 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and CFD expression is quantified. Does this perturbation result in a significant change in CFD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2062
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ENSG00000129757 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129757 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CDKN1C expression. Decide whether this perturbation leads to a significant alteration in CDKN1C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":448
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ENSG00000075624. Does perturbing TMSB4X lead to a significant change in ENSG00000075624 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ACTB. Does perturbing TMSB4X lead to a significant change in ACTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2861
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of ENSG00000004939 is measured. Does this perturbation cause a significant change in ENSG00000004939 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of SLC4A1 is measured. Does this perturbation cause a significant change in SLC4A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2630
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1668
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in ENSG00000273706 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":125
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is quantified. Does this perturbation result in a significant change in ENSG00000103241 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1092
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is measured. Determine whether ENSG00000079102 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is measured. Determine whether RUNX1T1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2439
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in ENSG00000188483 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in IER5L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1395
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and ENSG00000142945 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142945 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1633
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Determine whether ENSG00000258274 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Determine whether RP11-887P2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1366
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in ENSG00000255346 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in NOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2895
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ENSG00000184009. Does this perturbation cause a significant change in ENSG00000184009 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ACTG1. Does this perturbation cause a significant change in ACTG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2874
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000079102 is measured. Determine whether ENSG00000079102 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of RUNX1T1 is measured. Determine whether RUNX1T1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2446
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ENSG00000234965 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000234965 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor SHISA8 expression. Decide whether this perturbation leads to a significant alteration in SHISA8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2528
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2184
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":264
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in ENSG00000092067 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CEBPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":515
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2705
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ENSG00000130829 expression is measured. Determine whether ENSG00000130829 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and DUSP9 expression is measured. Determine whether DUSP9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":849
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ENSG00000130656. Does perturbing PTPN12 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of HBZ. Does perturbing PTPN12 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2291
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000184697 is measured. Determine whether ENSG00000184697 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CLDN6 is measured. Determine whether CLDN6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":646
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ENSG00000134321 expression is quantified. Does this perturbation result in a significant change in ENSG00000134321 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RSAD2 expression is quantified. Does this perturbation result in a significant change in RSAD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ENSG00000109099 expression is observed. Does this perturbation lead to a significant difference in ENSG00000109099 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and PMP22 expression is observed. Does this perturbation lead to a significant difference in PMP22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1193
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":855
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1825
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ENSG00000077063 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000077063 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor CTTNBP2 expression. Decide whether this perturbation leads to a significant alteration in CTTNBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor ENSG00000142945 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142945 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1628
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of ENSG00000273706. Does this perturbation cause a significant change in ENSG00000273706 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":124
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Determine whether ENSG00000164920 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Determine whether OSR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2106
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and ENSG00000070087 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070087 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and PFN2 expression is observed. Does this perturbation lead to a significant difference in PFN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":503
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000206172 is measured. Determine whether ENSG00000206172 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HBA1 is measured. Determine whether HBA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1456
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and ENSG00000206172 expression is measured. Determine whether ENSG00000206172 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and HBA1 expression is measured. Determine whether HBA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2469
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of ENSG00000163499. Does this perturbation cause a significant change in ENSG00000163499 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of CRYBA2. Does this perturbation cause a significant change in CRYBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":984
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ENSG00000130176. Does this perturbation cause a significant change in ENSG00000130176 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CNN1. Does this perturbation cause a significant change in CNN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":664
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2576
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and ENSG00000127831 expression is measured. Determine whether ENSG00000127831 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and VIL1 expression is measured. Determine whether VIL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1759
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor ENSG00000160185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000160185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2958
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2194
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2299
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ENSG00000163513 expression is observed. Does this perturbation lead to a significant difference in ENSG00000163513 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and TGFBR2 expression is observed. Does this perturbation lead to a significant difference in TGFBR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2823
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of ENSG00000258274. Does this perturbation cause a significant change in ENSG00000258274 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of RP11-887P2.5. Does this perturbation cause a significant change in RP11-887P2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1354
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of ENSG00000245848 is measured. Does this perturbation cause a significant change in ENSG00000245848 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of CEBPA is measured. Does this perturbation cause a significant change in CEBPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":550
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ENSG00000250361 expression is measured. Determine whether ENSG00000250361 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and GYPB expression is measured. Determine whether GYPB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ENSG00000158578. Does perturbing IER5L lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ALAS2. Does perturbing IER5L lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1401
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ENSG00000102575 expression is measured. Determine whether ENSG00000102575 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and ACP5 expression is measured. Determine whether ACP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2939
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ENSG00000258274 expression is quantified. Does this perturbation result in a significant change in ENSG00000258274 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and RP11-887P2.5 expression is quantified. Does this perturbation result in a significant change in RP11-887P2.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1312
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ENSG00000184486. Does perturbing POU3F2 lead to a significant change in ENSG00000184486 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of POU3F2. Does perturbing POU3F2 lead to a significant change in POU3F2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2161
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor ENSG00000169442 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169442 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":888
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ENSG00000134294. Does perturbing SLC38A2 lead to a significant change in ENSG00000134294 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of SLC38A2. Does perturbing SLC38A2 lead to a significant change in SLC38A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2581
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":565
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ENSG00000156030. Does perturbing ELMSAN1 lead to a significant change in ENSG00000156030 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ELMSAN1. Does perturbing ELMSAN1 lead to a significant change in ELMSAN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":911
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of ENSG00000085185. Does perturbing BCORL1 lead to a significant change in ENSG00000085185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of BCORL1. Does perturbing BCORL1 lead to a significant change in BCORL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":181
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in ENSG00000135409 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":225
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2183
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2210
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and ENSG00000153012 expression is measured. Determine whether ENSG00000153012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and LGI2 expression is measured. Determine whether LGI2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":489
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ENSG00000170542 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170542 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and SERPINB9 expression is observed. Does this perturbation lead to a significant difference in SERPINB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2533
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ENSG00000116871 is measured. Does this perturbation cause a significant change in ENSG00000116871 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1920
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of ENSG00000119535 is measured. Does this perturbation cause a significant change in ENSG00000119535 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":460
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":274
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of ENSG00000123473. Does perturbing STIL lead to a significant change in ENSG00000123473 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of STIL. Does perturbing STIL lead to a significant change in STIL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2741
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ENSG00000141744 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141744 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1653
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of ENSG00000164687. Does perturbing KMT2A lead to a significant change in ENSG00000164687 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of FABP5. Does perturbing KMT2A lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1691
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ENSG00000129757 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129757 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CDKN1C expression is observed. Does this perturbation lead to a significant difference in CDKN1C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":443
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1982
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor ENSG00000277268 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000277268 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor RP11-445F12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-445F12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1728
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ENSG00000158578. Does perturbing TGFBR2 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ALAS2. Does perturbing TGFBR2 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2841
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of ENSG00000163497 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1737
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and ENSG00000179111 expression is measured. Determine whether ENSG00000179111 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and HES7 expression is measured. Determine whether HES7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1209
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ENSG00000206172 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HBA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1457
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ENSG00000159556 is measured. Determine whether ENSG00000159556 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ISL2 is measured. Determine whether ISL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1506
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ENSG00000124762 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000124762 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CDKN1A expression. Decide whether this perturbation leads to a significant alteration in CDKN1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":378
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor ENSG00000169410 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169410 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PTPN9 expression. Decide whether this perturbation leads to a significant alteration in PTPN9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2358
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of ENSG00000154127. Does this perturbation cause a significant change in ENSG00000154127 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2984
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and ENSG00000092621 expression is quantified. Does this perturbation result in a significant change in ENSG00000092621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":742
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1828
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2185
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000205277 is measured. Determine whether ENSG00000205277 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of MUC12 is measured. Determine whether MUC12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3136
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ENSG00000115053 is measured. Does this perturbation cause a significant change in ENSG00000115053 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of NCL is measured. Does this perturbation cause a significant change in NCL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2040
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of ENSG00000198758 is measured. Does this perturbation cause a significant change in ENSG00000198758 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of EPS8L3 is measured. Does this perturbation cause a significant change in EPS8L3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1280
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of ENSG00000227053 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of RP11-395B7.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3127
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ENSG00000156030. Does this perturbation cause a significant change in ENSG00000156030 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ELMSAN1. Does this perturbation cause a significant change in ELMSAN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":914
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ENSG00000184486 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of POU3F2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2167
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000108821 is measured. Does this perturbation cause a significant change in ENSG00000108821 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of COL1A1 is measured. Does this perturbation cause a significant change in COL1A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":720
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and ENSG00000129514 expression is observed. Does this perturbation lead to a significant difference in ENSG00000129514 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FOXA1 expression is observed. Does this perturbation lead to a significant difference in FOXA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1023
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of ENSG00000129514. Does this perturbation cause a significant change in ENSG00000129514 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FOXA1. Does this perturbation cause a significant change in FOXA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1034
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000099625 is measured. Does this perturbation cause a significant change in ENSG00000099625 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of C19orf26 is measured. Does this perturbation cause a significant change in C19orf26 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":250
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Does this perturbation cause a significant change in ENSG00000188483 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Does this perturbation cause a significant change in IER5L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1380
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of ENSG00000090382 is measured. Does this perturbation cause a significant change in ENSG00000090382 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of LYZ is measured. Does this perturbation cause a significant change in LYZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1040
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2258
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ENSG00000144655 expression is measured. Determine whether ENSG00000144655 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and CSRNP1 expression is measured. Determine whether CSRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":789
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Determine whether ENSG00000142945 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1626
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of ENSG00000240065. Does this perturbation cause a significant change in ENSG00000240065 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of PSMB9. Does this perturbation cause a significant change in PSMB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1484
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ENSG00000163513 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163513 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor TGFBR2 expression. Decide whether this perturbation leads to a significant alteration in TGFBR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2828
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1660
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000163520 is measured. Does this perturbation cause a significant change in ENSG00000163520 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of FBLN2 is measured. Does this perturbation cause a significant change in FBLN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1180
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ENSG00000077063. Does perturbing AHR lead to a significant change in ENSG00000077063 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of CTTNBP2. Does perturbing AHR lead to a significant change in CTTNBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and ENSG00000142945 expression is quantified. Does this perturbation result in a significant change in ENSG00000142945 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1632
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ENSG00000250361. Does perturbing ATL1 lead to a significant change in ENSG00000250361 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of GYPB. Does perturbing ATL1 lead to a significant change in GYPB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ENSG00000108984 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in MAP2K6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1835
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ENSG00000120885 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000120885 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor CLU expression. Decide whether this perturbation leads to a significant alteration in CLU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2928
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in ENSG00000169410 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PTPN9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2345
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ENSG00000130176 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130176 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CNN1 expression. Decide whether this perturbation leads to a significant alteration in CNN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":678
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ENSG00000005187 expression is observed. Does this perturbation lead to a significant difference in ENSG00000005187 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":923
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ENSG00000158869 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158869 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3053
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ENSG00000139219 expression is observed. Does this perturbation lead to a significant difference in ENSG00000139219 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and COL2A1 expression is observed. Does this perturbation lead to a significant difference in COL2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":753
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and ENSG00000205277 expression is observed. Does this perturbation lead to a significant difference in ENSG00000205277 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and MUC12 expression is observed. Does this perturbation lead to a significant difference in MUC12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3133
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ENSG00000105939 expression is quantified. Does this perturbation result in a significant change in ENSG00000105939 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3092
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2199
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and ENSG00000030110 expression is observed. Does this perturbation lead to a significant difference in ENSG00000030110 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":143
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ENSG00000111348 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1975
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000135047 is measured. Determine whether ENSG00000135047 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3106
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ENSG00000157557 expression is measured. Determine whether ENSG00000157557 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ETS2 expression is measured. Determine whether ETS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":939
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and ENSG00000250361 expression is quantified. Does this perturbation result in a significant change in ENSG00000250361 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and GYPB expression is quantified. Does this perturbation result in a significant change in GYPB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2002
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ENSG00000158869. Does this perturbation cause a significant change in ENSG00000158869 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3054
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":380
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENSG00000182871. Does this perturbation cause a significant change in ENSG00000182871 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of COL18A1. Does this perturbation cause a significant change in COL18A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2324
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of ENSG00000070214. Does this perturbation cause a significant change in ENSG00000070214 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of SLC44A1. Does this perturbation cause a significant change in SLC44A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3014
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ENSG00000279576 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of AP000769.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1947
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of ENSG00000163513. Does perturbing TGFBR2 lead to a significant change in ENSG00000163513 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of TGFBR2. Does perturbing TGFBR2 lead to a significant change in TGFBR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2831
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of ENSG00000258274 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of RP11-887P2.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1357
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is quantified. Does this perturbation result in a significant change in ENSG00000196565 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and HBG2 expression is quantified. Does this perturbation result in a significant change in HBG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":312
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ENSG00000148180 expression is measured. Determine whether ENSG00000148180 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and GSN expression is measured. Determine whether GSN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1349
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ENSG00000076356 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in PLXNA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1785
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":268
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1515
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ENSG00000162878 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in PKDCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":605
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and ENSG00000273706 expression is observed. Does this perturbation lead to a significant difference in ENSG00000273706 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and ENSG00000162493 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162493 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PDPN expression is observed. Does this perturbation lead to a significant difference in PDPN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2623
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":873
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ENSG00000139219 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of COL2A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":757
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and ENSG00000154127 expression is observed. Does this perturbation lead to a significant difference in ENSG00000154127 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2973
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and ENSG00000183019 expression is observed. Does this perturbation lead to a significant difference in ENSG00000183019 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and MCEMP1 expression is observed. Does this perturbation lead to a significant difference in MCEMP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":173
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":874
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000141753 is measured. Does this perturbation cause a significant change in ENSG00000141753 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of IGFBP4 is measured. Does this perturbation cause a significant change in IGFBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2960
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor ENSG00000153012 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000153012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor LGI2 expression. Decide whether this perturbation leads to a significant alteration in LGI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":498
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and ENSG00000101200 expression is measured. Determine whether ENSG00000101200 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2799
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and ENSG00000026297 expression is quantified. Does this perturbation result in a significant change in ENSG00000026297 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and RNASET2 expression is quantified. Does this perturbation result in a significant change in RNASET2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":832
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor ENSG00000154127 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000154127 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2988
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and ENSG00000273706 expression is measured. Determine whether ENSG00000273706 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1719
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000034152 is measured. Determine whether ENSG00000034152 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of MAP2K3 is measured. Determine whether MAP2K3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1806
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ENSG00000148180 expression is quantified. Does this perturbation result in a significant change in ENSG00000148180 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and GSN expression is quantified. Does this perturbation result in a significant change in GSN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1342
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":535
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of ENSG00000154127. Does this perturbation cause a significant change in ENSG00000154127 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2974
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of ENSG00000153094. Does perturbing BCL2L11 lead to a significant change in ENSG00000153094 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of BCL2L11. Does perturbing BCL2L11 lead to a significant change in BCL2L11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":151
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":404
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of ENSG00000102804 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of TSC22D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2917
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":168
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1015
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000184481 is measured. Determine whether ENSG00000184481 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of FOXO4 is measured. Determine whether FOXO4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1146
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000105697 is measured. Determine whether ENSG00000105697 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of HAMP is measured. Determine whether HAMP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2486
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ENSG00000183770 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183770 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":298
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ENSG00000135047 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3105
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and ENSG00000092067 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092067 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CEBPE expression is observed. Does this perturbation lead to a significant difference in CEBPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":523
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and ENSG00000142945 expression is measured. Determine whether ENSG00000142945 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1629
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ENSG00000140545 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":615
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ENSG00000177606 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177606 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor JUN expression. Decide whether this perturbation leads to a significant alteration in JUN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1588
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in ENSG00000258274 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in RP11-887P2.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1365
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ENSG00000174498 expression is measured. Determine whether ENSG00000174498 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1419
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and ENSG00000196565 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196565 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and HBG2 expression is observed. Does this perturbation lead to a significant difference in HBG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2393
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2995
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ENSG00000268621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2577
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and ENSG00000240065 expression is measured. Determine whether ENSG00000240065 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and PSMB9 expression is measured. Determine whether PSMB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1489
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ENSG00000279576. Does this perturbation cause a significant change in ENSG00000279576 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of AP000769.1. Does this perturbation cause a significant change in AP000769.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1944
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ENSG00000120885. Does perturbing TSC22D1 lead to a significant change in ENSG00000120885 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of CLU. Does perturbing TSC22D1 lead to a significant change in CLU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2921
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ENSG00000069535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and MAOB expression is observed. Does this perturbation lead to a significant difference in MAOB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1533
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2242
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ENSG00000011600 expression is quantified. Does this perturbation result in a significant change in ENSG00000011600 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2722
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor ENSG00000104903 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000104903 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor LYL1 expression. Decide whether this perturbation leads to a significant alteration in LYL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1748
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ENSG00000158373. Does this perturbation cause a significant change in ENSG00000158373 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of HIST1H2BD. Does this perturbation cause a significant change in HIST1H2BD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2094
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ENSG00000188536 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1445
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of ENSG00000255346 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of NOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2897
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and ENSG00000092621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000092621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":743
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ENSG00000279669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000279669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor RP11-717F1.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-717F1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2678
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Determine whether ENSG00000139219 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Determine whether COL2A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":766
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":458
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ENSG00000268621. Does perturbing SLC38A2 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AC006262.5. Does perturbing SLC38A2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2591
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ENSG00000139219. Does perturbing COL2A1 lead to a significant change in ENSG00000139219 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of COL2A1. Does perturbing COL2A1 lead to a significant change in COL2A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":751
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor ENSG00000125144 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000125144 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor MT1G expression. Decide whether this perturbation leads to a significant alteration in MT1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":208
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ENSG00000129757 expression is measured. Determine whether ENSG00000129757 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CDKN1C expression is measured. Determine whether CDKN1C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":449
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of ENSG00000197965. Does perturbing OSR2 lead to a significant change in ENSG00000197965 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of MPZL1. Does perturbing OSR2 lead to a significant change in MPZL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2121
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of ENSG00000180785. Does perturbing IRF1 lead to a significant change in ENSG00000180785 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of OR51E1. Does perturbing IRF1 lead to a significant change in OR51E1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1471
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1989
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":878
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2296
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ENSG00000163513 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in TGFBR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2825
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2846
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ENSG00000166450 is measured. Does this perturbation cause a significant change in ENSG00000166450 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of PRTG is measured. Does this perturbation cause a significant change in PRTG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2230
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Does this perturbation cause a significant change in ENSG00000141744 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1650
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor ENSG00000163499 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163499 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor CRYBA2 expression. Decide whether this perturbation leads to a significant alteration in CRYBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":968
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ENSG00000187997 expression is measured. Determine whether ENSG00000187997 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and C17orf99 expression is measured. Determine whether C17orf99 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":439
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ENSG00000005187 expression is quantified. Does this perturbation result in a significant change in ENSG00000005187 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ACSM3 expression is quantified. Does this perturbation result in a significant change in ACSM3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":902
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000141753 is measured. Does this perturbation cause a significant change in ENSG00000141753 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of IGFBP4 is measured. Does this perturbation cause a significant change in IGFBP4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":390
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor ENSG00000153012 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000153012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor LGI2 expression. Decide whether this perturbation leads to a significant alteration in LGI2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":488
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is measured. Determine whether ENSG00000183770 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1129
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in ENSG00000179111 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in HES7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1205
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ENSG00000158869 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3057
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor ENSG00000121900 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000121900 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor TMEM54 expression. Decide whether this perturbation leads to a significant alteration in TMEM54 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2768
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in ENSG00000121900 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in TMEM54 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2775
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ENSG00000102575 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ACP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2935
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of ENSG00000196188 is measured. Does this perturbation cause a significant change in ENSG00000196188 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CTSE is measured. Does this perturbation cause a significant change in CTSE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1270
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ENSG00000133317 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in LGALS12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2455
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ENSG00000130829 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130829 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor DUSP9 expression. Decide whether this perturbation leads to a significant alteration in DUSP9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":848
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1106
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ENSG00000170180 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170180 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and GYPA expression is observed. Does this perturbation lead to a significant difference in GYPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":713
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2293
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ENSG00000119969 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of HELLS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2157
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and ENSG00000125144 expression is measured. Determine whether ENSG00000125144 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and MT1G expression is measured. Determine whether MT1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":209
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":532
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ENSG00000130176 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CNN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":675
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1817
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ENSG00000070214 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of SLC44A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1177
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":457
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1998
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1016
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of ENSG00000196565 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of HBG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2397
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and ENSG00000196517 expression is measured. Determine whether ENSG00000196517 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and SLC6A9 expression is measured. Determine whether SLC6A9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2649
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ENSG00000168140 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in VASN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2025
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ENSG00000188483 expression is observed. Does this perturbation lead to a significant difference in ENSG00000188483 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and IER5L expression is observed. Does this perturbation lead to a significant difference in IER5L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1393
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ENSG00000106546 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in AHR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of ENSG00000105223. Does perturbing HES7 lead to a significant change in ENSG00000105223 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of PLD3. Does perturbing HES7 lead to a significant change in PLD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1221
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ENSG00000135047 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1887
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ENSG00000170542 expression is quantified. Does this perturbation result in a significant change in ENSG00000170542 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and SERPINB9 expression is quantified. Does this perturbation result in a significant change in SERPINB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2532
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ENSG00000005187. Does this perturbation cause a significant change in ENSG00000005187 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":904
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000183019 is measured. Determine whether ENSG00000183019 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of MCEMP1 is measured. Determine whether MCEMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":176
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ENSG00000130656. Does perturbing ATL1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of HBZ. Does perturbing ATL1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ENSG00000140545. Does perturbing CKS1B lead to a significant change in ENSG00000140545 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of MFGE8. Does perturbing CKS1B lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":611
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000100097 is measured. Determine whether ENSG00000100097 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":806
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000143674 is measured. Does this perturbation cause a significant change in ENSG00000143674 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of KIAA1804 is measured. Does this perturbation cause a significant change in KIAA1804 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1560
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of ENSG00000197965 is measured. Does this perturbation cause a significant change in ENSG00000197965 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of MPZL1 is measured. Does this perturbation cause a significant change in MPZL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2120
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ENSG00000159556. Does perturbing ISL2 lead to a significant change in ENSG00000159556 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ISL2. Does perturbing ISL2 lead to a significant change in ISL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1501
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of ENSG00000184481. Does this perturbation cause a significant change in ENSG00000184481 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of FOXO4. Does this perturbation cause a significant change in FOXO4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1144
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ENSG00000113369 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ARRDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of ENSG00000135409. Does this perturbation cause a significant change in ENSG00000135409 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":224
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ENSG00000102575 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000102575 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor ACP5 expression. Decide whether this perturbation leads to a significant alteration in ACP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2938
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ENSG00000141753. Does perturbing CDKN1B lead to a significant change in ENSG00000141753 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of IGFBP4. Does perturbing CDKN1B lead to a significant change in IGFBP4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":391
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ENSG00000104894 expression is measured. Determine whether ENSG00000104894 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and CD37 expression is measured. Determine whether CD37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":779
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor ENSG00000163499 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163499 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor CRYBA2 expression. Decide whether this perturbation leads to a significant alteration in CRYBA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":988
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000184481 is measured. Does this perturbation cause a significant change in ENSG00000184481 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of FOXO4 is measured. Does this perturbation cause a significant change in FOXO4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1140
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of ENSG00000184697 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CLDN6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":647
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is quantified. Does this perturbation result in a significant change in ENSG00000154127 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2972
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1465
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and ENSG00000142945 expression is measured. Determine whether ENSG00000142945 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1639
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of ENSG00000247516. Does perturbing ZBTB25 lead to a significant change in ENSG00000247516 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of MIR4458HG. Does perturbing ZBTB25 lead to a significant change in MIR4458HG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3061
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ENSG00000100097 expression is measured. Determine whether ENSG00000100097 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":809
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of ENSG00000119535 is measured. Determine whether ENSG00000119535 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":466
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2688
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000110492 is measured. Determine whether ENSG00000110492 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of MDK is measured. Determine whether MDK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2206
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ENSG00000177606 is measured. Does this perturbation cause a significant change in ENSG00000177606 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of JUN is measured. Does this perturbation cause a significant change in JUN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1540
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ENSG00000213934 expression is observed. Does this perturbation lead to a significant difference in ENSG00000213934 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and HBG1 expression is observed. Does this perturbation lead to a significant difference in HBG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":323
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ENSG00000174498 expression is observed. Does this perturbation lead to a significant difference in ENSG00000174498 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1413
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ENSG00000183770 expression is quantified. Does this perturbation result in a significant change in ENSG00000183770 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1122
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is quantified. Does this perturbation result in a significant change in ENSG00000070214 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and SLC44A1 expression is quantified. Does this perturbation result in a significant change in SLC44A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3022
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2684
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ENSG00000169413. Does this perturbation cause a significant change in ENSG00000169413 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of RNASE6. Does this perturbation cause a significant change in RNASE6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1914
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ENSG00000149516 is measured. Determine whether ENSG00000149516 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of MS4A3 is measured. Determine whether MS4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":996
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":687
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ENSG00000157557 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of ETS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":937
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ENSG00000133317 is measured. Does this perturbation cause a significant change in ENSG00000133317 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of LGALS12 is measured. Does this perturbation cause a significant change in LGALS12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2450
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000169442 is measured. Does this perturbation cause a significant change in ENSG00000169442 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1950
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of ENSG00000203989 is measured. Does this perturbation cause a significant change in ENSG00000203989 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RHOXF2BB is measured. Does this perturbation cause a significant change in RHOXF2BB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2750
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is measured. Determine whether ENSG00000163513 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and TGFBR2 expression is measured. Determine whether TGFBR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2839
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of ENSG00000117091. Does perturbing HOXC13 lead to a significant change in ENSG00000117091 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of CD48. Does perturbing HOXC13 lead to a significant change in CD48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1371
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and ENSG00000108821 expression is quantified. Does this perturbation result in a significant change in ENSG00000108821 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and COL1A1 expression is quantified. Does this perturbation result in a significant change in COL1A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":722
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":233
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ENSG00000137841 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of PLCB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2137
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2362
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor ENSG00000250361 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000250361 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor GYPB expression. Decide whether this perturbation leads to a significant alteration in GYPB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2008
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor ENSG00000180785 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000180785 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor OR51E1 expression. Decide whether this perturbation leads to a significant alteration in OR51E1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1478
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ENSG00000260793 is measured. Determine whether ENSG00000260793 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP5-882C2.2 is measured. Determine whether RP5-882C2.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2146
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ENSG00000099625 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000099625 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor C19orf26 expression. Decide whether this perturbation leads to a significant alteration in C19orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":248
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and ENSG00000141753 expression is observed. Does this perturbation lead to a significant difference in ENSG00000141753 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and IGFBP4 expression is observed. Does this perturbation lead to a significant difference in IGFBP4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2963
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2694
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and ENSG00000026297 expression is measured. Determine whether ENSG00000026297 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and RNASET2 expression is measured. Determine whether RNASET2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":839
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ENSG00000184009 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ACTG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2877
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ENSG00000141744 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1525
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ENSG00000069535. Does this perturbation cause a significant change in ENSG00000069535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of MAOB. Does this perturbation cause a significant change in MAOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1534
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":564
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ENSG00000143369. Does perturbing PTPN12 lead to a significant change in ENSG00000143369 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ECM1. Does perturbing PTPN12 lead to a significant change in ECM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2301
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Does this perturbation cause a significant change in ENSG00000170689 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Does this perturbation cause a significant change in HOXB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1330
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ENSG00000157557 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ETS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":935
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000177606 is measured. Determine whether ENSG00000177606 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of JUN is measured. Determine whether JUN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1586
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1875
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ENSG00000234965 expression is quantified. Does this perturbation result in a significant change in ENSG00000234965 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and SHISA8 expression is quantified. Does this perturbation result in a significant change in SHISA8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2522
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in ENSG00000169442 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":885
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor ENSG00000143498 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143498 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor TAF1A expression. Decide whether this perturbation leads to a significant alteration in TAF1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2738
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000069482 is measured. Determine whether ENSG00000069482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of GAL is measured. Determine whether GAL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1136
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ENSG00000108984 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of MAP2K6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1837
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and ENSG00000153012 expression is observed. Does this perturbation lead to a significant difference in ENSG00000153012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and LGI2 expression is observed. Does this perturbation lead to a significant difference in LGI2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":493
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2269
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of ENSG00000141744. Does perturbing ISL2 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of PNMT. Does perturbing ISL2 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1521
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1077
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ENSG00000143674 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of KIAA1804 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1567
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ENSG00000134321 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000134321 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RSAD2 expression. Decide whether this perturbation leads to a significant alteration in RSAD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ENSG00000102804. Does perturbing TSC22D1 lead to a significant change in ENSG00000102804 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of TSC22D1. Does perturbing TSC22D1 lead to a significant change in TSC22D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2911
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in ENSG00000135111 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in TBX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2815
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ENSG00000143162 is measured. Does this perturbation cause a significant change in ENSG00000143162 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CREG1 is measured. Does this perturbation cause a significant change in CREG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1590
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of ENSG00000153012 is measured. Does this perturbation cause a significant change in ENSG00000153012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of LGI2 is measured. Does this perturbation cause a significant change in LGI2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":480
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor ENSG00000115844 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115844 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor DLX2 expression. Decide whether this perturbation leads to a significant alteration in DLX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":828
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and ENSG00000198758 expression is quantified. Does this perturbation result in a significant change in ENSG00000198758 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and EPS8L3 expression is quantified. Does this perturbation result in a significant change in EPS8L3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1282
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ENSG00000011600. Does this perturbation cause a significant change in ENSG00000011600 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2724
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ENSG00000115053 expression is quantified. Does this perturbation result in a significant change in ENSG00000115053 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and NCL expression is quantified. Does this perturbation result in a significant change in NCL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2042
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ENSG00000149516 is measured. Does this perturbation cause a significant change in ENSG00000149516 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of MS4A3 is measured. Does this perturbation cause a significant change in MS4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":990
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ENSG00000140287 expression is measured. Determine whether ENSG00000140287 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and HDC expression is measured. Determine whether HDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2179
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of ENSG00000163531. Does perturbing LYL1 lead to a significant change in ENSG00000163531 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of NFASC. Does perturbing LYL1 lead to a significant change in NFASC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1761
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":166
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1436
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ENSG00000129757 expression is quantified. Does this perturbation result in a significant change in ENSG00000129757 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CDKN1C expression is quantified. Does this perturbation result in a significant change in CDKN1C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":412
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of ENSG00000104903. Does this perturbation cause a significant change in ENSG00000104903 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of LYL1. Does this perturbation cause a significant change in LYL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1744
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ENSG00000157557 expression is quantified. Does this perturbation result in a significant change in ENSG00000157557 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and ETS2 expression is quantified. Does this perturbation result in a significant change in ETS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":932
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and ENSG00000117091 expression is observed. Does this perturbation lead to a significant difference in ENSG00000117091 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and CD48 expression is observed. Does this perturbation lead to a significant difference in CD48 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1373
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ENSG00000189171 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2695
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1439
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1810
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ENSG00000069535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of MAOB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1537
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":790
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000189171 is measured. Does this perturbation cause a significant change in ENSG00000189171 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2690
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ENSG00000169442 expression is quantified. Does this perturbation result in a significant change in ENSG00000169442 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1952
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and ENSG00000247516 expression is observed. Does this perturbation lead to a significant difference in ENSG00000247516 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and MIR4458HG expression is observed. Does this perturbation lead to a significant difference in MIR4458HG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3083
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ENSG00000034152 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in MAP2K3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1805
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ENSG00000169413 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of RNASE6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1917
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2366
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of ENSG00000188483. Does this perturbation cause a significant change in ENSG00000188483 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of IER5L. Does this perturbation cause a significant change in IER5L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1394
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":858
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ENSG00000234965 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of SHISA8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2527
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is measured. Determine whether ENSG00000169410 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PTPN9 expression is measured. Determine whether PTPN9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2349
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ENSG00000130303 is measured. Does this perturbation cause a significant change in ENSG00000130303 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3030
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2654
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor ENSG00000115844 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115844 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor DLX2 expression. Decide whether this perturbation leads to a significant alteration in DLX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ENSG00000213934 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in HBG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":325
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ENSG00000106031 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of HOXA13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1297
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ENSG00000115738. Does perturbing MIDN lead to a significant change in ENSG00000115738 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ID2. Does perturbing MIDN lead to a significant change in ID2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2011
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of ENSG00000186051. Does perturbing PTPN13 lead to a significant change in ENSG00000186051 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of TAL2. Does perturbing PTPN13 lead to a significant change in TAL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2331
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ENSG00000174498 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1417
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and ENSG00000068078 expression is quantified. Does this perturbation result in a significant change in ENSG00000068078 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and FGFR3 expression is quantified. Does this perturbation result in a significant change in FGFR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and ENSG00000254614 expression is measured. Determine whether ENSG00000254614 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and AP003068.23 expression is measured. Determine whether AP003068.23 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2619
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of ENSG00000188536. Does this perturbation cause a significant change in ENSG00000188536 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of HBA2. Does this perturbation cause a significant change in HBA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2474
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of ENSG00000164920 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of OSR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2117
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2518
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ENSG00000142669 is measured. Does this perturbation cause a significant change in ENSG00000142669 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of SH3BGRL3 is measured. Does this perturbation cause a significant change in SH3BGRL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1010
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1909
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2999
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":685
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ENSG00000135047 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2605
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":693
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ENSG00000106546 is measured. Determine whether ENSG00000106546 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of AHR is measured. Determine whether AHR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and ENSG00000204482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":453
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ENSG00000102575. Does perturbing TSC22D1 lead to a significant change in ENSG00000102575 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of ACP5. Does perturbing TSC22D1 lead to a significant change in ACP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2931
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000129757 is measured. Determine whether ENSG00000129757 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CDKN1C is measured. Determine whether CDKN1C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":416
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2372
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and ENSG00000163497 expression is quantified. Does this perturbation result in a significant change in ENSG00000163497 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":972
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2378
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000090238 is measured. Does this perturbation cause a significant change in ENSG00000090238 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of YPEL3 is measured. Does this perturbation cause a significant change in YPEL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1160
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ENSG00000250361 is measured. Determine whether ENSG00000250361 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of GYPB is measured. Determine whether GYPB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2493
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor ENSG00000206172 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000206172 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor HBA1 expression. Decide whether this perturbation leads to a significant alteration in HBA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2468
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000268621 is measured. Does this perturbation cause a significant change in ENSG00000268621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ENSG00000162878 expression is quantified. Does this perturbation result in a significant change in ENSG00000162878 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and PKDCC expression is quantified. Does this perturbation result in a significant change in PKDCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":602
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor ENSG00000184481 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184481 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor FOXO4 expression. Decide whether this perturbation leads to a significant alteration in FOXO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1148
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ENSG00000268621 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000268621 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor ENSG00000272211 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000272211 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor RP11-347P5.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-347P5.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1708
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2496
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ENSG00000143401. Does perturbing NIT1 lead to a significant change in ENSG00000143401 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ANP32E. Does perturbing NIT1 lead to a significant change in ANP32E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2081
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":266
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ENSG00000102575 expression is observed. Does this perturbation lead to a significant difference in ENSG00000102575 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ACP5 expression is observed. Does this perturbation lead to a significant difference in ACP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2933
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2254
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Determine whether ENSG00000103241 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1096
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of ENSG00000166340. Does perturbing FOXO4 lead to a significant change in ENSG00000166340 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of TPP1. Does perturbing FOXO4 lead to a significant change in TPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1151
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Does this perturbation cause a significant change in ENSG00000164920 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Does this perturbation cause a significant change in OSR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2110
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and ENSG00000163497 expression is measured. Determine whether ENSG00000163497 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1739
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of ENSG00000117139. Does this perturbation cause a significant change in ENSG00000117139 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of KDM5B. Does this perturbation cause a significant change in KDM5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3144
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ENSG00000177606. Does this perturbation cause a significant change in ENSG00000177606 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of JUN. Does this perturbation cause a significant change in JUN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1544
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2842
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is measured. Determine whether ENSG00000154127 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2979
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of ENSG00000164920. Does this perturbation cause a significant change in ENSG00000164920 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of OSR2. Does this perturbation cause a significant change in OSR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2104
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000196517 is measured. Does this perturbation cause a significant change in ENSG00000196517 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of SLC6A9 is measured. Does this perturbation cause a significant change in SLC6A9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2640
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1652
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":237
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2219
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ENSG00000166501 is measured. Determine whether ENSG00000166501 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2546
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and ENSG00000092621 expression is measured. Determine whether ENSG00000092621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":749
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and ENSG00000247516 expression is observed. Does this perturbation lead to a significant difference in ENSG00000247516 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and MIR4458HG expression is observed. Does this perturbation lead to a significant difference in MIR4458HG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3063
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and ENSG00000163499 expression is measured. Determine whether ENSG00000163499 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and CRYBA2 expression is measured. Determine whether CRYBA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":989
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ENSG00000115053. Does perturbing NCL lead to a significant change in ENSG00000115053 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of NCL. Does perturbing NCL lead to a significant change in NCL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2041
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and ENSG00000069011 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069011 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and PITX1 expression is observed. Does this perturbation lead to a significant difference in PITX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1213
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor ENSG00000101200 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101200 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2808
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2718
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is quantified. Does this perturbation result in a significant change in ENSG00000163513 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and TGFBR2 expression is quantified. Does this perturbation result in a significant change in TGFBR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2822
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ENSG00000128016 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ZFP36 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2055
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor ENSG00000164687 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000164687 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1698
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and ENSG00000115844 expression is quantified. Does this perturbation result in a significant change in ENSG00000115844 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and DLX2 expression is quantified. Does this perturbation result in a significant change in DLX2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":822
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of ENSG00000188483. Does perturbing IER5L lead to a significant change in ENSG00000188483 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of IER5L. Does perturbing IER5L lead to a significant change in IER5L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1381
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2214
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ENSG00000196565 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of HBG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":307
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ENSG00000158578. Does perturbing MAP4K5 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ALAS2. Does perturbing MAP4K5 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1891
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of ENSG00000163497. Does perturbing FEV lead to a significant change in ENSG00000163497 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of FEV. Does perturbing FEV lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":971
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ENSG00000205542 expression is measured. Determine whether ENSG00000205542 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TMSB4X expression is measured. Determine whether TMSB4X exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2859
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ENSG00000110492 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000110492 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor MDK expression. Decide whether this perturbation leads to a significant alteration in MDK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2208
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of ENSG00000110492 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of MDK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2207
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ENSG00000158578. Does perturbing FOXA3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ALAS2. Does perturbing FOXA3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1071
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ENSG00000116871 expression is observed. Does this perturbation lead to a significant difference in ENSG00000116871 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1923
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ENSG00000174498 expression is observed. Does this perturbation lead to a significant difference in ENSG00000174498 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1423
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ENSG00000070214. Does perturbing ZBTB1 lead to a significant change in ENSG00000070214 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of SLC44A1. Does perturbing ZBTB1 lead to a significant change in SLC44A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3011
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ENSG00000102804 expression is observed. Does this perturbation lead to a significant difference in ENSG00000102804 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and TSC22D1 expression is observed. Does this perturbation lead to a significant difference in TSC22D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2913
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in ENSG00000153012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in LGI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":485
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000075624 is measured. Does this perturbation cause a significant change in ENSG00000075624 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ACTB is measured. Does this perturbation cause a significant change in ACTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2860
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ENSG00000077063 expression is measured. Determine whether ENSG00000077063 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CTTNBP2 expression is measured. Determine whether CTTNBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1619
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is quantified. Does this perturbation result in a significant change in ENSG00000170689 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and HOXB9 expression is quantified. Does this perturbation result in a significant change in HOXB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1332
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is measured. Determine whether ENSG00000170689 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and HOXB9 expression is measured. Determine whether HOXB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1329
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of ENSG00000272211 is measured. Does this perturbation cause a significant change in ENSG00000272211 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of RP11-347P5.1 is measured. Does this perturbation cause a significant change in RP11-347P5.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1700
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in ENSG00000129514 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1025
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and ENSG00000159399 expression is observed. Does this perturbation lead to a significant difference in ENSG00000159399 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and HK2 expression is observed. Does this perturbation lead to a significant difference in HK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1233
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of ENSG00000272211 is measured. Determine whether ENSG00000272211 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of RP11-347P5.1 is measured. Determine whether RP11-347P5.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1706
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000182871 is measured. Does this perturbation cause a significant change in ENSG00000182871 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of COL18A1 is measured. Does this perturbation cause a significant change in COL18A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2320
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ENSG00000076356 is measured. Determine whether ENSG00000076356 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of PLXNA2 is measured. Determine whether PLXNA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1786
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ENSG00000099625. Does this perturbation cause a significant change in ENSG00000099625 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of C19orf26. Does this perturbation cause a significant change in C19orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":244
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ENSG00000189171. Does perturbing ZBTB10 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of S100A13. Does perturbing ZBTB10 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3041
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of ENSG00000092621. Does perturbing COL1A1 lead to a significant change in ENSG00000092621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of PHGDH. Does perturbing COL1A1 lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":741
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ENSG00000130829 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of DUSP9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":847
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ENSG00000128016 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000128016 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ZFP36 expression. Decide whether this perturbation leads to a significant alteration in ZFP36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2058
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ENSG00000105610 is measured. Does this perturbation cause a significant change in ENSG00000105610 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of KLF1 is measured. Does this perturbation cause a significant change in KLF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1670
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of ENSG00000277268. Does this perturbation cause a significant change in ENSG00000277268 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of RP11-445F12.1. Does this perturbation cause a significant change in RP11-445F12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1724
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2907
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ENSG00000184486 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184486 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor POU3F2 expression. Decide whether this perturbation leads to a significant alteration in POU3F2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2168
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000092621 is measured. Determine whether ENSG00000092621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":746
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000070214 is measured. Determine whether ENSG00000070214 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of SLC44A1 is measured. Determine whether SLC44A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1176
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ENSG00000183770. Does perturbing FOXL2 lead to a significant change in ENSG00000183770 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FOXL2. Does perturbing FOXL2 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1121
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of ENSG00000273706 is measured. Determine whether ENSG00000273706 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":126
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1070
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ENSG00000034152 expression is quantified. Does this perturbation result in a significant change in ENSG00000034152 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and MAP2K3 expression is quantified. Does this perturbation result in a significant change in MAP2K3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1802
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ENSG00000170608 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in FOXA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1065
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of ENSG00000143498 is measured. Does this perturbation cause a significant change in ENSG00000143498 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of TAF1A is measured. Does this perturbation cause a significant change in TAF1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2730
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in ENSG00000104903 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in LYL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1745
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of ENSG00000196188. Does perturbing HNF4A lead to a significant change in ENSG00000196188 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CTSE. Does perturbing HNF4A lead to a significant change in CTSE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1271
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1253
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ENSG00000113594 expression is measured. Determine whether ENSG00000113594 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and LIFR expression is measured. Determine whether LIFR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1799
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000213934 is measured. Does this perturbation cause a significant change in ENSG00000213934 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of HBG1 is measured. Does this perturbation cause a significant change in HBG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":320
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of ENSG00000169442 is measured. Determine whether ENSG00000169442 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":886
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ENSG00000196565 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in HBG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":315
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is quantified. Does this perturbation result in a significant change in ENSG00000247516 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and MIR4458HG expression is quantified. Does this perturbation result in a significant change in MIR4458HG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3082
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1985
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ENSG00000079102 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000079102 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor RUNX1T1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1T1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2448
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in ENSG00000160185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2955
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ENSG00000163520. Does perturbing GLB1L2 lead to a significant change in ENSG00000163520 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of FBLN2. Does perturbing GLB1L2 lead to a significant change in FBLN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1181
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is measured. Determine whether ENSG00000247516 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and MIR4458HG expression is measured. Determine whether MIR4458HG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3089
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":699
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of ENSG00000118058. Does this perturbation cause a significant change in ENSG00000118058 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of KMT2A. Does this perturbation cause a significant change in KMT2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1684
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ENSG00000139219. Does perturbing COL2A1 lead to a significant change in ENSG00000139219 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of COL2A1. Does perturbing COL2A1 lead to a significant change in COL2A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":761
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ENSG00000204482 expression is measured. Determine whether ENSG00000204482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2709
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of ENSG00000135111 is measured. Determine whether ENSG00000135111 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of TBX3 is measured. Determine whether TBX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2816
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":279
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ENSG00000170542 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of SERPINB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2537
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ENSG00000189171. Does perturbing FOXF1 lead to a significant change in ENSG00000189171 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of S100A13. Does perturbing FOXF1 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1101
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and ENSG00000243449 expression is measured. Determine whether ENSG00000243449 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and C4orf48 expression is measured. Determine whether C4orf48 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":549
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ENSG00000128016 expression is observed. Does this perturbation lead to a significant difference in ENSG00000128016 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ZFP36 expression is observed. Does this perturbation lead to a significant difference in ZFP36 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2053
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3075
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":160
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in ENSG00000092621 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":745
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ENSG00000177606 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000177606 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor JUN expression. Decide whether this perturbation leads to a significant alteration in JUN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1548
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000205277 is measured. Does this perturbation cause a significant change in ENSG00000205277 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of MUC12 is measured. Does this perturbation cause a significant change in MUC12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3130
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ENSG00000205542 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000205542 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TMSB4X expression. Decide whether this perturbation leads to a significant alteration in TMSB4X expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2858
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ENSG00000231312 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000231312 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AC007246.3 expression. Decide whether this perturbation leads to a significant alteration in AC007246.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1868
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of ENSG00000026297 is measured. Determine whether ENSG00000026297 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of RNASET2 is measured. Determine whether RNASET2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":836
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ENSG00000108984 expression is measured. Determine whether ENSG00000108984 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and MAP2K6 expression is measured. Determine whether MAP2K6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1849
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and ENSG00000101200 expression is measured. Determine whether ENSG00000101200 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2889
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000250361 is measured. Does this perturbation cause a significant change in ENSG00000250361 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of GYPB is measured. Does this perturbation cause a significant change in GYPB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2180
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2998
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and ENSG00000197965 expression is measured. Determine whether ENSG00000197965 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and MPZL1 expression is measured. Determine whether MPZL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2129
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of ENSG00000272211. Does perturbing KMT2A lead to a significant change in ENSG00000272211 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of RP11-347P5.1. Does perturbing KMT2A lead to a significant change in RP11-347P5.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1701
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2263
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and ENSG00000064886 expression is quantified. Does this perturbation result in a significant change in ENSG00000064886 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2902
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ENSG00000279576 expression is measured. Determine whether ENSG00000279576 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and AP000769.1 expression is measured. Determine whether AP000769.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1949
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor ENSG00000183019 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183019 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor MCEMP1 expression. Decide whether this perturbation leads to a significant alteration in MCEMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":178
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ENSG00000187997. Does perturbing CDKN1C lead to a significant change in ENSG00000187997 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of C17orf99. Does perturbing CDKN1C lead to a significant change in C17orf99 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":431
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is quantified. Does this perturbation result in a significant change in ENSG00000160185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2942
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ENSG00000130176. Does perturbing CNN1 lead to a significant change in ENSG00000130176 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CNN1. Does perturbing CNN1 lead to a significant change in CNN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":661
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ENSG00000268621 is measured. Determine whether ENSG00000268621 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ENSG00000170689 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170689 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and HOXB9 expression is observed. Does this perturbation lead to a significant difference in HOXB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1323
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ENSG00000162878 is measured. Determine whether ENSG00000162878 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of PKDCC is measured. Determine whether PKDCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":606
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ENSG00000196565. Does this perturbation cause a significant change in ENSG00000196565 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of HBG2. Does this perturbation cause a significant change in HBG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":304
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Does this perturbation cause a significant change in ENSG00000183770 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1120
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000135047 is measured. Does this perturbation cause a significant change in ENSG00000135047 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3100
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor ENSG00000141753 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141753 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor IGFBP4 expression. Decide whether this perturbation leads to a significant alteration in IGFBP4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":398
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ENSG00000102575. Does this perturbation cause a significant change in ENSG00000102575 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ACP5. Does this perturbation cause a significant change in ACP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2934
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000188536 is measured. Determine whether ENSG00000188536 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HBA2 is measured. Determine whether HBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1446
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of ENSG00000180785 is measured. Does this perturbation cause a significant change in ENSG00000180785 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of OR51E1 is measured. Does this perturbation cause a significant change in OR51E1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1470
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1522
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000005187 is measured. Does this perturbation cause a significant change in ENSG00000005187 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1570
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":276
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ENSG00000170542 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170542 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor SERPINB9 expression. Decide whether this perturbation leads to a significant alteration in SERPINB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2538
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ENSG00000166501 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2545
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2573
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ENSG00000158578. Does perturbing MAP4K3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ALAS2. Does perturbing MAP4K3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1871
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of ENSG00000101200 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2807
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of ENSG00000250361. Does this perturbation cause a significant change in ENSG00000250361 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of GYPB. Does this perturbation cause a significant change in GYPB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2004
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and ENSG00000169410 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169410 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PTPN9 expression is observed. Does this perturbation lead to a significant difference in PTPN9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2353
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in ENSG00000196517 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in SLC6A9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2645
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ENSG00000005187 expression is measured. Determine whether ENSG00000005187 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ACSM3 expression is measured. Determine whether ACSM3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in ENSG00000102804 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in TSC22D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2915
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ENSG00000069482. Does perturbing FOXL2 lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of GAL. Does perturbing FOXL2 lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1131
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1433
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in ENSG00000121068 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in TBX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2785
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of ENSG00000069011 is measured. Determine whether ENSG00000069011 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of PITX1 is measured. Determine whether PITX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1216
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and ENSG00000254614 expression is observed. Does this perturbation lead to a significant difference in ENSG00000254614 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and AP003068.23 expression is observed. Does this perturbation lead to a significant difference in AP003068.23 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2613
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ENSG00000113594 expression is quantified. Does this perturbation result in a significant change in ENSG00000113594 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and LIFR expression is quantified. Does this perturbation result in a significant change in LIFR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1792
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ENSG00000204482. Does this perturbation cause a significant change in ENSG00000204482 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2704
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ENSG00000149516 expression is measured. Determine whether ENSG00000149516 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and MS4A3 expression is measured. Determine whether MS4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":999
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of ENSG00000245532 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of NEAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":597
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ENSG00000156030 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ELMSAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":915
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of ENSG00000069482 is measured. Does this perturbation cause a significant change in ENSG00000069482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of GAL is measured. Does this perturbation cause a significant change in GAL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2380
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ENSG00000090382 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LYZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1057
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2844
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ENSG00000166501 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166501 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2543
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of ENSG00000030110. Does this perturbation cause a significant change in ENSG00000030110 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":144
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of ENSG00000272211. Does this perturbation cause a significant change in ENSG00000272211 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of RP11-347P5.1. Does this perturbation cause a significant change in RP11-347P5.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1704
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of ENSG00000101076. Does perturbing HNF4A lead to a significant change in ENSG00000101076 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of HNF4A. Does perturbing HNF4A lead to a significant change in HNF4A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1261
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and ENSG00000101200 expression is quantified. Does this perturbation result in a significant change in ENSG00000101200 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2802
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of ENSG00000130656. Does perturbing SLC6A9 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of HBZ. Does perturbing SLC6A9 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2651
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1000
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1876
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ENSG00000137841 is measured. Determine whether ENSG00000137841 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of PLCB2 is measured. Determine whether PLCB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2136
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of ENSG00000255346. Does this perturbation cause a significant change in ENSG00000255346 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of NOX5. Does this perturbation cause a significant change in NOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2894
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":857
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of ENSG00000090382. Does perturbing FOXA1 lead to a significant change in ENSG00000090382 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of LYZ. Does perturbing FOXA1 lead to a significant change in LYZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1041
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2367
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ENSG00000064886. Does perturbing MAP2K3 lead to a significant change in ENSG00000064886 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of CHI3L2. Does perturbing MAP2K3 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1811
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and ENSG00000188483 expression is quantified. Does this perturbation result in a significant change in ENSG00000188483 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and IER5L expression is quantified. Does this perturbation result in a significant change in IER5L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1392
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":876
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and ENSG00000069011 expression is measured. Determine whether ENSG00000069011 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and PITX1 expression is measured. Determine whether PITX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1219
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ENSG00000213934 expression is quantified. Does this perturbation result in a significant change in ENSG00000213934 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and HBG1 expression is quantified. Does this perturbation result in a significant change in HBG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":322
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and ENSG00000124762 expression is observed. Does this perturbation lead to a significant difference in ENSG00000124762 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CDKN1A expression is observed. Does this perturbation lead to a significant difference in CDKN1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":363
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2295
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and ENSG00000166340 expression is measured. Determine whether ENSG00000166340 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and TPP1 expression is measured. Determine whether TPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1159
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ENSG00000143369. Does this perturbation cause a significant change in ENSG00000143369 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ECM1. Does this perturbation cause a significant change in ECM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2304
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of ENSG00000188536 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HBA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1447
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor ENSG00000158517 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158517 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor NCF1 expression. Decide whether this perturbation leads to a significant alteration in NCF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":478
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in ENSG00000115844 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in DLX2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":825
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in ENSG00000254614 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in AP003068.23 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2615
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and ENSG00000101200 expression is quantified. Does this perturbation result in a significant change in ENSG00000101200 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2792
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1102
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ENSG00000162878 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of PKDCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":607
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ENSG00000075624 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of ACTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2867
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2193
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000186051 is measured. Does this perturbation cause a significant change in ENSG00000186051 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of TAL2 is measured. Does this perturbation cause a significant change in TAL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2330
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ENSG00000143369 expression is quantified. Does this perturbation result in a significant change in ENSG00000143369 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ECM1 expression is quantified. Does this perturbation result in a significant change in ECM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2302
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ENSG00000079102 expression is observed. Does this perturbation lead to a significant difference in ENSG00000079102 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and RUNX1T1 expression is observed. Does this perturbation lead to a significant difference in RUNX1T1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2443
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ENSG00000117091. Does this perturbation cause a significant change in ENSG00000117091 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of CD48. Does this perturbation cause a significant change in CD48 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1304
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":388
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of ENSG00000163531. Does this perturbation cause a significant change in ENSG00000163531 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of NFASC. Does this perturbation cause a significant change in NFASC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1764
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ENSG00000187997 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000187997 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor C17orf99 expression. Decide whether this perturbation leads to a significant alteration in C17orf99 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":438
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and ENSG00000115844 expression is measured. Determine whether ENSG00000115844 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and DLX2 expression is measured. Determine whether DLX2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":829
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2289
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and ENSG00000125931 expression is measured. Determine whether ENSG00000125931 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and CITED1 expression is measured. Determine whether CITED1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":579
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000154127 is measured. Does this perturbation cause a significant change in ENSG00000154127 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2980
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ENSG00000177606. Does this perturbation cause a significant change in ENSG00000177606 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of JUN. Does this perturbation cause a significant change in JUN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1584
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and ENSG00000101200 expression is observed. Does this perturbation lead to a significant difference in ENSG00000101200 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2883
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is quantified. Does this perturbation result in a significant change in ENSG00000124762 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CDKN1A expression is quantified. Does this perturbation result in a significant change in CDKN1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":362
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ENSG00000234965. Does this perturbation cause a significant change in ENSG00000234965 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of SHISA8. Does this perturbation cause a significant change in SHISA8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2524
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ENSG00000162878 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162878 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor PKDCC expression. Decide whether this perturbation leads to a significant alteration in PKDCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":608
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ENSG00000077063 is measured. Does this perturbation cause a significant change in ENSG00000077063 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CTTNBP2 is measured. Does this perturbation cause a significant change in CTTNBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1610
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ENSG00000143674. Does perturbing KIAA1804 lead to a significant change in ENSG00000143674 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of KIAA1804. Does perturbing KIAA1804 lead to a significant change in KIAA1804 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1561
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of ENSG00000160185 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2947
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ENSG00000156030 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000156030 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ELMSAN1 expression. Decide whether this perturbation leads to a significant alteration in ELMSAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":918
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1464
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ENSG00000143401 is measured. Does this perturbation cause a significant change in ENSG00000143401 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ANP32E is measured. Does this perturbation cause a significant change in ANP32E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2080
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":697
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor ENSG00000070214 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070214 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor SLC44A1 expression. Decide whether this perturbation leads to a significant alteration in SLC44A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3018
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of ENSG00000279529. Does perturbing KIF2C lead to a significant change in ENSG00000279529 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of CTD-3222D19.8. Does perturbing KIF2C lead to a significant change in CTD-3222D19.8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1641
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of ENSG00000183770 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":297
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and ENSG00000180785 expression is measured. Determine whether ENSG00000180785 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and OR51E1 expression is measured. Determine whether OR51E1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1479
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2492
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ENSG00000184009. Does perturbing TMSB4X lead to a significant change in ENSG00000184009 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of ACTG1. Does perturbing TMSB4X lead to a significant change in ACTG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2871
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000183019 is measured. Does this perturbation cause a significant change in ENSG00000183019 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of MCEMP1 is measured. Does this perturbation cause a significant change in MCEMP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":170
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of ENSG00000205277. Does perturbing ZNF318 lead to a significant change in ENSG00000205277 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of MUC12. Does perturbing ZNF318 lead to a significant change in MUC12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3131
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ENSG00000134294. Does this perturbation cause a significant change in ENSG00000134294 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of SLC38A2. Does this perturbation cause a significant change in SLC38A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2584
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of ENSG00000143498 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of TAF1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2737
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ENSG00000157557 expression is observed. Does this perturbation lead to a significant difference in ENSG00000157557 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ETS2 expression is observed. Does this perturbation lead to a significant difference in ETS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":933
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2240
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":235
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Does this perturbation cause a significant change in ENSG00000115844 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Does this perturbation cause a significant change in DLX2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":810
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and ENSG00000125144 expression is quantified. Does this perturbation result in a significant change in ENSG00000125144 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and MT1G expression is quantified. Does this perturbation result in a significant change in MT1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":202
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor ENSG00000069482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor GAL expression. Decide whether this perturbation leads to a significant alteration in GAL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":898
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENSG00000106991 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000106991 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENG expression. Decide whether this perturbation leads to a significant alteration in ENG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2318
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and ENSG00000141744 expression is quantified. Does this perturbation result in a significant change in ENSG00000141744 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1512
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000111348 is measured. Determine whether ENSG00000111348 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1976
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ENSG00000139219 expression is observed. Does this perturbation lead to a significant difference in ENSG00000139219 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and COL2A1 expression is observed. Does this perturbation lead to a significant difference in COL2A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":763
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ENSG00000135047 expression is quantified. Does this perturbation result in a significant change in ENSG00000135047 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2602
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ENSG00000184486 is measured. Does this perturbation cause a significant change in ENSG00000184486 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of POU3F2 is measured. Does this perturbation cause a significant change in POU3F2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2160
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of ENSG00000154127 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2987
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Determine whether ENSG00000139219 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Determine whether COL2A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":756
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000258274 is measured. Does this perturbation cause a significant change in ENSG00000258274 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of RP11-887P2.5 is measured. Does this perturbation cause a significant change in RP11-887P2.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1310
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ENSG00000204482. Does perturbing FOSB lead to a significant change in ENSG00000204482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of LST1. Does perturbing FOSB lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1001
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2993
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and ENSG00000160185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000160185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2943
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ENSG00000115738 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ID2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2015
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ENSG00000128016. Does perturbing NCL lead to a significant change in ENSG00000128016 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ZFP36. Does perturbing NCL lead to a significant change in ZFP36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2051
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000143369 is measured. Does this perturbation cause a significant change in ENSG00000143369 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ECM1 is measured. Does this perturbation cause a significant change in ECM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2300
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ENSG00000157557 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in ETS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":955
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ENSG00000064886 expression is observed. Does this perturbation lead to a significant difference in ENSG00000064886 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1813
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ENSG00000268621. Does perturbing ARRDC3 lead to a significant change in ENSG00000268621 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of AC006262.5. Does perturbing ARRDC3 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1905
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ENSG00000168140. Does perturbing MIDN lead to a significant change in ENSG00000168140 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of VASN. Does perturbing MIDN lead to a significant change in VASN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2021
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of ENSG00000170608 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of FOXA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1067
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000169413 is measured. Does this perturbation cause a significant change in ENSG00000169413 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of RNASE6 is measured. Does this perturbation cause a significant change in RNASE6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1910
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor ENSG00000159399 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159399 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor HK2 expression. Decide whether this perturbation leads to a significant alteration in HK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1238
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor ENSG00000064886 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000064886 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2428
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ENSG00000157557 expression is observed. Does this perturbation lead to a significant difference in ENSG00000157557 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and ETS2 expression is observed. Does this perturbation lead to a significant difference in ETS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":953
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":429
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2257
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of ENSG00000186051. Does this perturbation cause a significant change in ENSG00000186051 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of TAL2. Does this perturbation cause a significant change in TAL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2334
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ENSG00000134321. Does perturbing AHR lead to a significant change in ENSG00000134321 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RSAD2. Does perturbing AHR lead to a significant change in RSAD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":238
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is quantified. Does this perturbation result in a significant change in ENSG00000129514 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FOXA1 expression is quantified. Does this perturbation result in a significant change in FOXA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1032
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ENSG00000139219 is measured. Does this perturbation cause a significant change in ENSG00000139219 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of COL2A1 is measured. Does this perturbation cause a significant change in COL2A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":750
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ENSG00000069535. Does perturbing JUN lead to a significant change in ENSG00000069535 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of MAOB. Does perturbing JUN lead to a significant change in MAOB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1531
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ENSG00000149516. Does perturbing FOSB lead to a significant change in ENSG00000149516 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of MS4A3. Does perturbing FOSB lead to a significant change in MS4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":991
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of ENSG00000124762. Does this perturbation cause a significant change in ENSG00000124762 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CDKN1A. Does this perturbation cause a significant change in CDKN1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":374
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of ENSG00000068078. Does this perturbation cause a significant change in ENSG00000068078 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of FGFR3. Does this perturbation cause a significant change in FGFR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ENSG00000141744. Does perturbing KLF1 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of PNMT. Does perturbing KLF1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1651
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000108821 is measured. Determine whether ENSG00000108821 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":726
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ENSG00000158578. Does perturbing CDKN1C lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ALAS2. Does perturbing CDKN1C lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":421
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of ENSG00000101200. Does this perturbation cause a significant change in ENSG00000101200 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2884
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in ENSG00000227053 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in RP11-395B7.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3125
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ENSG00000258274. Does this perturbation cause a significant change in ENSG00000258274 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of RP11-887P2.5. Does this perturbation cause a significant change in RP11-887P2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1314
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of ENSG00000141744 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1517
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":359
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ENSG00000117091 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000117091 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor CD48 expression. Decide whether this perturbation leads to a significant alteration in CD48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1308
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor ENSG00000258274 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000258274 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor RP11-887P2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-887P2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1368
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ENSG00000143162 is measured. Determine whether ENSG00000143162 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CREG1 is measured. Determine whether CREG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1596
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ENSG00000177606 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in JUN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1545
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2413
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ENSG00000114315 is measured. Determine whether ENSG00000114315 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of HES1 is measured. Determine whether HES1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2036
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ENSG00000256713 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PGA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":705
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2003
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ENSG00000159556 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000159556 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ISL2 expression. Decide whether this perturbation leads to a significant alteration in ISL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1508
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is measured. Determine whether ENSG00000258274 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is measured. Determine whether RP11-887P2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1359
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is measured. Determine whether ENSG00000103241 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1089
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ENSG00000159556 is measured. Does this perturbation cause a significant change in ENSG00000159556 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of ISL2 is measured. Does this perturbation cause a significant change in ISL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1500
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Determine whether ENSG00000030110 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":136
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of ENSG00000163497 is measured. Determine whether ENSG00000163497 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1736
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ENSG00000204472 expression is observed. Does this perturbation lead to a significant difference in ENSG00000204472 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1963
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1872
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1994
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ENSG00000266976 is measured. Determine whether ENSG00000266976 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of AC079466.1 is measured. Determine whether AC079466.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1856
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130829 is measured. Does this perturbation cause a significant change in ENSG00000130829 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of DUSP9 is measured. Does this perturbation cause a significant change in DUSP9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":840
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ENSG00000266976 expression is measured. Determine whether ENSG00000266976 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and AC079466.1 expression is measured. Determine whether AC079466.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1859
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ENSG00000260793 is measured. Does this perturbation cause a significant change in ENSG00000260793 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP5-882C2.2 is measured. Does this perturbation cause a significant change in RP5-882C2.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2140
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ENSG00000206172. Does perturbing PTPN1 lead to a significant change in ENSG00000206172 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of HBA1. Does perturbing PTPN1 lead to a significant change in HBA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2271
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of ENSG00000120885. Does this perturbation cause a significant change in ENSG00000120885 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of CLU. Does this perturbation cause a significant change in CLU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2924
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ENSG00000162878 expression is observed. Does this perturbation lead to a significant difference in ENSG00000162878 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and PKDCC expression is observed. Does this perturbation lead to a significant difference in PKDCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":603
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of ENSG00000198758. Does this perturbation cause a significant change in ENSG00000198758 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of EPS8L3. Does this perturbation cause a significant change in EPS8L3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1284
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ENSG00000113594 is measured. Determine whether ENSG00000113594 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of LIFR is measured. Determine whether LIFR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1796
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ENSG00000231312 is measured. Determine whether ENSG00000231312 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Determine whether AC007246.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1866
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of ENSG00000154127. Does perturbing UBASH3B lead to a significant change in ENSG00000154127 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2981
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of ENSG00000162493. Does perturbing SLC4A1 lead to a significant change in ENSG00000162493 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PDPN. Does perturbing SLC4A1 lead to a significant change in PDPN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2621
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of ENSG00000092067 is measured. Determine whether ENSG00000092067 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CEBPE is measured. Determine whether CEBPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":526
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and ENSG00000121900 expression is measured. Determine whether ENSG00000121900 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and TMEM54 expression is measured. Determine whether TMEM54 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2779
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of ENSG00000203989. Does perturbing STIL lead to a significant change in ENSG00000203989 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of RHOXF2BB. Does perturbing STIL lead to a significant change in RHOXF2BB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2751
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ENSG00000185198. Does perturbing PTPN1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of PRSS57. Does perturbing PTPN1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2261
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ENSG00000135047 is measured. Does this perturbation cause a significant change in ENSG00000135047 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2600
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ENSG00000234965 expression is observed. Does this perturbation lead to a significant difference in ENSG00000234965 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and SHISA8 expression is observed. Does this perturbation lead to a significant difference in SHISA8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2523
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":345
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and ENSG00000135111 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135111 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and TBX3 expression is observed. Does this perturbation lead to a significant difference in TBX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2813
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of ENSG00000245532. Does perturbing CITED1 lead to a significant change in ENSG00000245532 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of NEAT1. Does perturbing CITED1 lead to a significant change in NEAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":591
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and ENSG00000198758 expression is measured. Determine whether ENSG00000198758 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and EPS8L3 expression is measured. Determine whether EPS8L3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1289
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":263
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ENSG00000100097 expression is quantified. Does this perturbation result in a significant change in ENSG00000100097 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":802
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ENSG00000143674 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in KIAA1804 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1565
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ENSG00000170689 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of HOXB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1327
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ENSG00000117091. Does perturbing HOXA13 lead to a significant change in ENSG00000117091 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of CD48. Does perturbing HOXA13 lead to a significant change in CD48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1301
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":356
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of ENSG00000254614. Does this perturbation cause a significant change in ENSG00000254614 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of AP003068.23. Does this perturbation cause a significant change in AP003068.23 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2614
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and ENSG00000160838 expression is quantified. Does this perturbation result in a significant change in ENSG00000160838 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and LRRC71 expression is quantified. Does this perturbation result in a significant change in LRRC71 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1983
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is quantified. Does this perturbation result in a significant change in ENSG00000160185 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2952
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":895
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENSG00000106991 expression is measured. Determine whether ENSG00000106991 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and ENG expression is measured. Determine whether ENG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2319
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ENSG00000189171 is measured. Determine whether ENSG00000189171 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2076
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ENSG00000111348. Does this perturbation cause a significant change in ENSG00000111348 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1974
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2996
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000111348 is measured. Does this perturbation cause a significant change in ENSG00000111348 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1970
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ENSG00000118515 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000118515 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor SGK1 expression. Decide whether this perturbation leads to a significant alteration in SGK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2558
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ENSG00000143369 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ECM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2305
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000111057 is measured. Determine whether ENSG00000111057 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of KRT18 is measured. Determine whether KRT18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":196
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ENSG00000069535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in MAOB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1535
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":405
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and ENSG00000119535 expression is observed. Does this perturbation lead to a significant difference in ENSG00000119535 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of ENSG00000125931 is measured. Determine whether ENSG00000125931 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of CITED1 is measured. Determine whether CITED1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":576
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ENSG00000106546 expression is measured. Determine whether ENSG00000106546 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and AHR expression is measured. Determine whether AHR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and ENSG00000117091 expression is quantified. Does this perturbation result in a significant change in ENSG00000117091 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and CD48 expression is quantified. Does this perturbation result in a significant change in CD48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1372
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ENSG00000148180 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of GSN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1347
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ENSG00000184009 expression is measured. Determine whether ENSG00000184009 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ACTG1 expression is measured. Determine whether ACTG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2879
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in ENSG00000180785 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in OR51E1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1475
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ENSG00000130303 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3037
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of ENSG00000129757. Does perturbing CDKN1B lead to a significant change in ENSG00000129757 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CDKN1C. Does perturbing CDKN1B lead to a significant change in CDKN1C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":411
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENSG00000106991 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2317
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and ENSG00000105697 expression is quantified. Does this perturbation result in a significant change in ENSG00000105697 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and HAMP expression is quantified. Does this perturbation result in a significant change in HAMP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2482
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor ENSG00000243449 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000243449 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor C4orf48 expression. Decide whether this perturbation leads to a significant alteration in C4orf48 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":548
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in ENSG00000070087 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in PFN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":505
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of ENSG00000101200. Does perturbing TBX3 lead to a significant change in ENSG00000101200 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of AVP. Does perturbing TBX3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2801
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ENSG00000139219 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in COL2A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":755
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ENSG00000158869. Does perturbing ZBTB10 lead to a significant change in ENSG00000158869 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of FCER1G. Does perturbing ZBTB10 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3051
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of ENSG00000069482. Does perturbing RHOXF2BB lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of GAL. Does perturbing RHOXF2BB lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2381
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of ENSG00000153012. Does perturbing CEBPB lead to a significant change in ENSG00000153012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of LGI2. Does perturbing CEBPB lead to a significant change in LGI2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":481
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of ENSG00000125144. Does this perturbation cause a significant change in ENSG00000125144 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of MT1G. Does this perturbation cause a significant change in MT1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":204
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":386
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of ENSG00000255346. Does perturbing TP73 lead to a significant change in ENSG00000255346 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of NOX5. Does perturbing TP73 lead to a significant change in NOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2891
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in ENSG00000196188 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CTSE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1275
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in ENSG00000164920 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in OSR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2105
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and ENSG00000071967 expression is measured. Determine whether ENSG00000071967 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and CYBRD1 expression is measured. Determine whether CYBRD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1499
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor ENSG00000197965 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000197965 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor MPZL1 expression. Decide whether this perturbation leads to a significant alteration in MPZL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2128
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":355
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ENSG00000102804 expression is observed. Does this perturbation lead to a significant difference in ENSG00000102804 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and TSC22D1 expression is observed. Does this perturbation lead to a significant difference in TSC22D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":283
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ENSG00000104894. Does this perturbation cause a significant change in ENSG00000104894 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of CD37. Does this perturbation cause a significant change in CD37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":774
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000177606 is measured. Does this perturbation cause a significant change in ENSG00000177606 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of JUN is measured. Does this perturbation cause a significant change in JUN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1580
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ENSG00000166501 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166501 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2548
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ENSG00000231312. Does this perturbation cause a significant change in ENSG00000231312 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AC007246.3. Does this perturbation cause a significant change in AC007246.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1864
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Determine whether ENSG00000030110 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":146
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ENSG00000124762 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CDKN1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":377
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2712
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ENSG00000113369 expression is observed. Does this perturbation lead to a significant difference in ENSG00000113369 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ARRDC3 expression is observed. Does this perturbation lead to a significant difference in ARRDC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ENSG00000197766 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of CFD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2067
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ENSG00000113594 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of LIFR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1797
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ENSG00000099625. Does perturbing C19orf26 lead to a significant change in ENSG00000099625 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of C19orf26. Does perturbing C19orf26 lead to a significant change in C19orf26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":251
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of ENSG00000143498 is measured. Determine whether ENSG00000143498 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of TAF1A is measured. Determine whether TAF1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2736
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of ENSG00000188483 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of IER5L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1387
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and ENSG00000168209 expression is quantified. Does this perturbation result in a significant change in ENSG00000168209 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and DDIT4 expression is quantified. Does this perturbation result in a significant change in DDIT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":732
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and ENSG00000142945 expression is observed. Does this perturbation lead to a significant difference in ENSG00000142945 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1623
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and ENSG00000110492 expression is measured. Determine whether ENSG00000110492 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and MDK expression is measured. Determine whether MDK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2209
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of ENSG00000243449. Does perturbing CELF2 lead to a significant change in ENSG00000243449 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of C4orf48. Does perturbing CELF2 lead to a significant change in C4orf48 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":541
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ENSG00000170542 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in SERPINB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2535
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":354
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ENSG00000169442. Does this perturbation cause a significant change in ENSG00000169442 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1954
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ENSG00000118515 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of SGK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2557
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ENSG00000069482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of GAL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1137
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":400
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ENSG00000070214 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in SLC44A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1175
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1516
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000279669 is measured. Determine whether ENSG00000279669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of RP11-717F1.1 is measured. Determine whether RP11-717F1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2676
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1250
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of ENSG00000197965 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of MPZL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2127
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of ENSG00000101076. Does this perturbation cause a significant change in ENSG00000101076 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of HNF4A. Does this perturbation cause a significant change in HNF4A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1264
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of ENSG00000159399 is measured. Does this perturbation cause a significant change in ENSG00000159399 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of HK2 is measured. Does this perturbation cause a significant change in HK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1230
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1079
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is quantified. Does this perturbation result in a significant change in ENSG00000184697 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CLDN6 expression is quantified. Does this perturbation result in a significant change in CLDN6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":632
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1528
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1903
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ENSG00000099625. Does this perturbation cause a significant change in ENSG00000099625 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of C19orf26. Does this perturbation cause a significant change in C19orf26 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":254
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000105697 is measured. Does this perturbation cause a significant change in ENSG00000105697 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of HAMP is measured. Does this perturbation cause a significant change in HAMP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2480
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ENSG00000266976. Does perturbing MAP2K6 lead to a significant change in ENSG00000266976 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of AC079466.1. Does perturbing MAP2K6 lead to a significant change in AC079466.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1851
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ENSG00000135047 expression is measured. Determine whether ENSG00000135047 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3109
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of ENSG00000169410. Does this perturbation cause a significant change in ENSG00000169410 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PTPN9. Does this perturbation cause a significant change in PTPN9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2344
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ENSG00000156030 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ELMSAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":917
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor ENSG00000247516 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000247516 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor MIR4458HG expression. Decide whether this perturbation leads to a significant alteration in MIR4458HG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3068
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ENSG00000184486 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184486 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and POU3F2 expression is observed. Does this perturbation lead to a significant difference in POU3F2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2163
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":426
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2845
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of ENSG00000101200. Does this perturbation cause a significant change in ENSG00000101200 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2794
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of ENSG00000186051 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of TAL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2337
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is measured. Determine whether ENSG00000124762 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":369
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor ENSG00000090382 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000090382 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor LYZ expression. Decide whether this perturbation leads to a significant alteration in LYZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1048
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and ENSG00000105697 expression is measured. Determine whether ENSG00000105697 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and HAMP expression is measured. Determine whether HAMP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2489
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000118777 is measured. Determine whether ENSG00000118777 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of ABCG2 is measured. Determine whether ABCG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3006
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ENSG00000143162. Does perturbing KIF18B lead to a significant change in ENSG00000143162 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CREG1. Does perturbing KIF18B lead to a significant change in CREG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1591
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":650
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3070
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and ENSG00000164920 expression is observed. Does this perturbation lead to a significant difference in ENSG00000164920 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and OSR2 expression is observed. Does this perturbation lead to a significant difference in OSR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2113
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ENSG00000157557 is measured. Does this perturbation cause a significant change in ENSG00000157557 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ETS2 is measured. Does this perturbation cause a significant change in ETS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":950
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Does this perturbation cause a significant change in ENSG00000247516 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Does this perturbation cause a significant change in MIR4458HG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3080
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of ENSG00000185198 is measured. Does this perturbation cause a significant change in ENSG00000185198 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2510
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of ENSG00000153012. Does this perturbation cause a significant change in ENSG00000153012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of LGI2. Does this perturbation cause a significant change in LGI2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":494
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of ENSG00000071967 is measured. Determine whether ENSG00000071967 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of CYBRD1 is measured. Determine whether CYBRD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1496
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor ENSG00000160838 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000160838 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor LRRC71 expression. Decide whether this perturbation leads to a significant alteration in LRRC71 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor ENSG00000129514 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000129514 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FOXA1 expression. Decide whether this perturbation leads to a significant alteration in FOXA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1038
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ENSG00000134321. Does this perturbation cause a significant change in ENSG00000134321 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RSAD2. Does this perturbation cause a significant change in RSAD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1815
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of ENSG00000159399 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of HK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1237
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ENSG00000106546 expression is quantified. Does this perturbation result in a significant change in ENSG00000106546 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and AHR expression is quantified. Does this perturbation result in a significant change in AHR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ENSG00000099625 expression is observed. Does this perturbation lead to a significant difference in ENSG00000099625 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and C19orf26 expression is observed. Does this perturbation lead to a significant difference in C19orf26 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":243
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and ENSG00000068078 expression is observed. Does this perturbation lead to a significant difference in ENSG00000068078 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and FGFR3 expression is observed. Does this perturbation lead to a significant difference in FGFR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ENSG00000170180 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000170180 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor GYPA expression. Decide whether this perturbation leads to a significant alteration in GYPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":718
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ENSG00000213934. Does perturbing CBFA2T3 lead to a significant change in ENSG00000213934 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of HBG1. Does perturbing CBFA2T3 lead to a significant change in HBG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":321
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ENSG00000204472. Does this perturbation cause a significant change in ENSG00000204472 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1964
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in ENSG00000184697 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CLDN6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":645
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ENSG00000100097 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000100097 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":808
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ENSG00000103241 expression is observed. Does this perturbation lead to a significant difference in ENSG00000103241 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1093
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ENSG00000250361 expression is observed. Does this perturbation lead to a significant difference in ENSG00000250361 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and GYPB expression is observed. Does this perturbation lead to a significant difference in GYPB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ENSG00000076356 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of PLXNA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1787
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1107
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ENSG00000140545 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":617
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of ENSG00000092067 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CEBPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":517
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ENSG00000114315 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of HES1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2037
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ENSG00000162878 is measured. Does this perturbation cause a significant change in ENSG00000162878 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of PKDCC is measured. Does this perturbation cause a significant change in PKDCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":600
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2503
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ENSG00000130176 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CNN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":677
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and ENSG00000162493 expression is quantified. Does this perturbation result in a significant change in ENSG00000162493 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PDPN expression is quantified. Does this perturbation result in a significant change in PDPN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2622
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of ENSG00000185198. Does perturbing MEIS1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1981
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ENSG00000166501 expression is quantified. Does this perturbation result in a significant change in ENSG00000166501 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2542
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ENSG00000117091 expression is quantified. Does this perturbation result in a significant change in ENSG00000117091 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and CD48 expression is quantified. Does this perturbation result in a significant change in CD48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1302
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of ENSG00000104903. Does perturbing LYL1 lead to a significant change in ENSG00000104903 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of LYL1. Does perturbing LYL1 lead to a significant change in LYL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1741
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of ENSG00000183770. Does this perturbation cause a significant change in ENSG00000183770 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":294
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ENSG00000185198 is measured. Determine whether ENSG00000185198 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2266
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ENSG00000184009 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000184009 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ACTG1 expression. Decide whether this perturbation leads to a significant alteration in ACTG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2878
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ENSG00000258274. Does perturbing HOXA13 lead to a significant change in ENSG00000258274 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of RP11-887P2.5. Does perturbing HOXA13 lead to a significant change in RP11-887P2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1311
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and ENSG00000185198 expression is quantified. Does this perturbation result in a significant change in ENSG00000185198 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1992
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of ENSG00000159399. Does this perturbation cause a significant change in ENSG00000159399 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of HK2. Does this perturbation cause a significant change in HK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1234
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ENSG00000143162. Does this perturbation cause a significant change in ENSG00000143162 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CREG1. Does this perturbation cause a significant change in CREG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1594
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of ENSG00000070087 is measured. Does this perturbation cause a significant change in ENSG00000070087 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of PFN2 is measured. Does this perturbation cause a significant change in PFN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":500
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of ENSG00000121900 is measured. Determine whether ENSG00000121900 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of TMEM54 is measured. Determine whether TMEM54 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2766
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in ENSG00000064886 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2905
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ENSG00000141744. Does this perturbation cause a significant change in ENSG00000141744 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1654
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ENSG00000143674 is measured. Determine whether ENSG00000143674 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of KIAA1804 is measured. Determine whether KIAA1804 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1566
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ENSG00000158373 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158373 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor HIST1H2BD expression. Decide whether this perturbation leads to a significant alteration in HIST1H2BD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2098
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of ENSG00000273706. Does perturbing BAK1 lead to a significant change in ENSG00000273706 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of LHX1. Does perturbing BAK1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ENSG00000005187. Does this perturbation cause a significant change in ENSG00000005187 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ACSM3. Does this perturbation cause a significant change in ACSM3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1574
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ENSG00000135047 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135047 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3108
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of ENSG00000265972. Does perturbing HK2 lead to a significant change in ENSG00000265972 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of TXNIP. Does perturbing HK2 lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1241
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ENSG00000158578 expression is quantified. Does this perturbation result in a significant change in ENSG00000158578 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":402
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ENSG00000130176 expression is quantified. Does this perturbation result in a significant change in ENSG00000130176 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CNN1 expression is quantified. Does this perturbation result in a significant change in CNN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":662
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ENSG00000156030 expression is quantified. Does this perturbation result in a significant change in ENSG00000156030 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ELMSAN1 expression is quantified. Does this perturbation result in a significant change in ELMSAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":912
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and ENSG00000117139 expression is quantified. Does this perturbation result in a significant change in ENSG00000117139 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and KDM5B expression is quantified. Does this perturbation result in a significant change in KDM5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3142
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of ENSG00000163531 is measured. Determine whether ENSG00000163531 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of NFASC is measured. Determine whether NFASC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1766
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and ENSG00000090238 expression is measured. Determine whether ENSG00000090238 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and YPEL3 expression is measured. Determine whether YPEL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1169
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of ENSG00000068078 is measured. Determine whether ENSG00000068078 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of FGFR3 is measured. Determine whether FGFR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of ENSG00000064886 is measured. Does this perturbation cause a significant change in ENSG00000064886 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2900
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ENSG00000258274 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000258274 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor RP11-887P2.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-887P2.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1318
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of ENSG00000203989 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of RHOXF2BB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2757
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of ENSG00000160185. Does perturbing UBASH3A lead to a significant change in ENSG00000160185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2951
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ENSG00000130656. Does perturbing CNNM4 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of HBZ. Does perturbing CNNM4 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":691
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ENSG00000135047. Does perturbing SLC38A2 lead to a significant change in ENSG00000135047 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of CTSL. Does perturbing SLC38A2 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2601
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ENSG00000130303. Does perturbing ZBTB10 lead to a significant change in ENSG00000130303 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of BST2. Does perturbing ZBTB10 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3031
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of ENSG00000196517 is measured. Determine whether ENSG00000196517 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of SLC6A9 is measured. Determine whether SLC6A9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2646
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":690
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ENSG00000184486 expression is quantified. Does this perturbation result in a significant change in ENSG00000184486 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and POU3F2 expression is quantified. Does this perturbation result in a significant change in POU3F2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2162
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ENSG00000118777 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ABCG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3005
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ENSG00000166450 expression is observed. Does this perturbation lead to a significant difference in ENSG00000166450 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and PRTG expression is observed. Does this perturbation lead to a significant difference in PRTG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2233
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ENSG00000079102 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of RUNX1T1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2437
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102575 is measured. Does this perturbation cause a significant change in ENSG00000102575 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of ACP5 is measured. Does this perturbation cause a significant change in ACP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2930
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ENSG00000206172 expression is measured. Determine whether ENSG00000206172 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and HBA1 expression is measured. Determine whether HBA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2279
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of ENSG00000158517. Does perturbing CEBPA lead to a significant change in ENSG00000158517 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of NCF1. Does perturbing CEBPA lead to a significant change in NCF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":471
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ENSG00000197766 is measured. Determine whether ENSG00000197766 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of CFD is measured. Determine whether CFD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2066
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor ENSG00000162493 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000162493 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PDPN expression. Decide whether this perturbation leads to a significant alteration in PDPN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2628
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ENSG00000186185 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000186185 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor KIF18B expression. Decide whether this perturbation leads to a significant alteration in KIF18B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1608
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":407
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ENSG00000005187 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000005187 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":908
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ENSG00000148180. Does perturbing HOXB9 lead to a significant change in ENSG00000148180 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of GSN. Does perturbing HOXB9 lead to a significant change in GSN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1341
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2245
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ENSG00000234965 is measured. Determine whether ENSG00000234965 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of SHISA8 is measured. Determine whether SHISA8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2526
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in ENSG00000204482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":455
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ENSG00000158373 is measured. Determine whether ENSG00000158373 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of HIST1H2BD is measured. Determine whether HIST1H2BD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2096
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and ENSG00000153094 expression is measured. Determine whether ENSG00000153094 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and BCL2L11 expression is measured. Determine whether BCL2L11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":159
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Determine whether ENSG00000142945 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1636
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of ENSG00000164687 is measured. Determine whether ENSG00000164687 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1696
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ENSG00000169413 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169413 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor RNASE6 expression. Decide whether this perturbation leads to a significant alteration in RNASE6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1918
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in ENSG00000153012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in LGI2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":495
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ENSG00000268621 expression is measured. Determine whether ENSG00000268621 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3119
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ENSG00000196565 expression is observed. Does this perturbation lead to a significant difference in ENSG00000196565 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and HBG2 expression is observed. Does this perturbation lead to a significant difference in HBG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":303
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of ENSG00000142945 is measured. Does this perturbation cause a significant change in ENSG00000142945 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1620
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ENSG00000189171. Does this perturbation cause a significant change in ENSG00000189171 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1104
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in ENSG00000206172 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HBA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1455
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ENSG00000170180 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of GYPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":717
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of ENSG00000162493. Does this perturbation cause a significant change in ENSG00000162493 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PDPN. Does this perturbation cause a significant change in PDPN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2624
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of ENSG00000092067. Does perturbing CEBPE lead to a significant change in ENSG00000092067 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CEBPE. Does perturbing CEBPE lead to a significant change in CEBPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":511
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ENSG00000135047 expression is observed. Does this perturbation lead to a significant difference in ENSG00000135047 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3103
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and ENSG00000169410 expression is quantified. Does this perturbation result in a significant change in ENSG00000169410 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PTPN9 expression is quantified. Does this perturbation result in a significant change in PTPN9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2352
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ENSG00000069535 expression is quantified. Does this perturbation result in a significant change in ENSG00000069535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and MAOB expression is quantified. Does this perturbation result in a significant change in MAOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1532
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ENSG00000128016 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ZFP36 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2057
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and ENSG00000273706 expression is observed. Does this perturbation lead to a significant difference in ENSG00000273706 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1713
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of ENSG00000158517 is measured. Does this perturbation cause a significant change in ENSG00000158517 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of NCF1 is measured. Does this perturbation cause a significant change in NCF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":470
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000125144 is measured. Does this perturbation cause a significant change in ENSG00000125144 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of MT1G is measured. Does this perturbation cause a significant change in MT1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":200
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of ENSG00000163497 is measured. Determine whether ENSG00000163497 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":976
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and ENSG00000245532 expression is observed. Does this perturbation lead to a significant difference in ENSG00000245532 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and NEAT1 expression is observed. Does this perturbation lead to a significant difference in NEAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":593
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3078
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and ENSG00000120885 expression is observed. Does this perturbation lead to a significant difference in ENSG00000120885 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and CLU expression is observed. Does this perturbation lead to a significant difference in CLU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2923
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ENSG00000115053 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in NCL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2045
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of ENSG00000183019 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of MCEMP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":177
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and ENSG00000123473 expression is quantified. Does this perturbation result in a significant change in ENSG00000123473 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and STIL expression is quantified. Does this perturbation result in a significant change in STIL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2742
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and ENSG00000164920 expression is observed. Does this perturbation lead to a significant difference in ENSG00000164920 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and OSR2 expression is observed. Does this perturbation lead to a significant difference in OSR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2103
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ENSG00000148180 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000148180 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor GSN expression. Decide whether this perturbation leads to a significant alteration in GSN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1348
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ENSG00000196565 expression is measured. Determine whether ENSG00000196565 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and HBG2 expression is measured. Determine whether HBG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":319
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ENSG00000100097. Does this perturbation cause a significant change in ENSG00000100097 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":804
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ENSG00000130303 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130303 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3038
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ENSG00000168140 expression is quantified. Does this perturbation result in a significant change in ENSG00000168140 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and VASN expression is quantified. Does this perturbation result in a significant change in VASN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2022
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ENSG00000184009 is measured. Does this perturbation cause a significant change in ENSG00000184009 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of ACTG1 is measured. Does this perturbation cause a significant change in ACTG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2870
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ENSG00000187997 expression is quantified. Does this perturbation result in a significant change in ENSG00000187997 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and C17orf99 expression is quantified. Does this perturbation result in a significant change in C17orf99 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":432
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ENSG00000075624 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000075624 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor ACTB expression. Decide whether this perturbation leads to a significant alteration in ACTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2868
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of ENSG00000092621. Does this perturbation cause a significant change in ENSG00000092621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":744
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and ENSG00000203989 expression is measured. Determine whether ENSG00000203989 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and RHOXF2BB expression is measured. Determine whether RHOXF2BB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2759
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and ENSG00000111057 expression is observed. Does this perturbation lead to a significant difference in ENSG00000111057 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and KRT18 expression is observed. Does this perturbation lead to a significant difference in KRT18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":193
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor ENSG00000237330 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000237330 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor RNF223 expression. Decide whether this perturbation leads to a significant alteration in RNF223 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2408
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2389
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ENSG00000157557. Does this perturbation cause a significant change in ENSG00000157557 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ETS2. Does this perturbation cause a significant change in ETS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":934
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ENSG00000103241 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1097
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1257
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000117091 is measured. Determine whether ENSG00000117091 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of CD48 is measured. Determine whether CD48 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1306
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ENSG00000186185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000186185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and KIF18B expression is observed. Does this perturbation lead to a significant difference in KIF18B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1603
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ENSG00000118515 expression is quantified. Does this perturbation result in a significant change in ENSG00000118515 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and SGK1 expression is quantified. Does this perturbation result in a significant change in SGK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2552
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of ENSG00000184697. Does perturbing CLDN6 lead to a significant change in ENSG00000184697 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CLDN6. Does perturbing CLDN6 lead to a significant change in CLDN6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":641
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of ENSG00000130656. Does perturbing ZBTB25 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of HBZ. Does perturbing ZBTB25 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3071
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ENSG00000166501 is measured. Does this perturbation cause a significant change in ENSG00000166501 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2540
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ENSG00000143162 expression is measured. Determine whether ENSG00000143162 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CREG1 expression is measured. Determine whether CREG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1599
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and ENSG00000030110 expression is quantified. Does this perturbation result in a significant change in ENSG00000030110 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":132
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor ENSG00000196188 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000196188 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CTSE expression. Decide whether this perturbation leads to a significant alteration in CTSE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1278
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor ENSG00000121068 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000121068 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor TBX2 expression. Decide whether this perturbation leads to a significant alteration in TBX2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2788
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1435
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor ENSG00000030110 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000030110 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":138
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ENSG00000204472 is measured. Determine whether ENSG00000204472 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1966
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ENSG00000189171 expression is quantified. Does this perturbation result in a significant change in ENSG00000189171 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2692
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and ENSG00000206172 expression is quantified. Does this perturbation result in a significant change in ENSG00000206172 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and HBA1 expression is quantified. Does this perturbation result in a significant change in HBA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2462
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ENSG00000163520. Does this perturbation cause a significant change in ENSG00000163520 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of FBLN2. Does this perturbation cause a significant change in FBLN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1184
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1258
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and ENSG00000101200 expression is measured. Determine whether ENSG00000101200 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2809
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000106991 is measured. Does this perturbation cause a significant change in ENSG00000106991 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of ENG is measured. Does this perturbation cause a significant change in ENG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2310
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ENSG00000129757 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CDKN1C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":447
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2843
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of ENSG00000227053 is measured. Determine whether ENSG00000227053 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of RP11-395B7.4 is measured. Determine whether RP11-395B7.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3126
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1899
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and ENSG00000135111 expression is measured. Determine whether ENSG00000135111 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and TBX3 expression is measured. Determine whether TBX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2819
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ENSG00000204472 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1967
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of ENSG00000119535. Does this perturbation cause a significant change in ENSG00000119535 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":584
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of ENSG00000125144 is measured. Determine whether ENSG00000125144 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of MT1G is measured. Determine whether MT1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":206
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ENSG00000135047 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1885
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ENSG00000163520 expression is measured. Determine whether ENSG00000163520 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and FBLN2 expression is measured. Determine whether FBLN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1189
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ENSG00000116871. Does this perturbation cause a significant change in ENSG00000116871 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1924
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ENSG00000113369 expression is measured. Determine whether ENSG00000113369 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ARRDC3 expression is measured. Determine whether ARRDC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2686
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ENSG00000105610 expression is observed. Does this perturbation lead to a significant difference in ENSG00000105610 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and KLF1 expression is observed. Does this perturbation lead to a significant difference in KLF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1673
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ENSG00000115053 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of NCL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2047
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":865
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of ENSG00000159399 is measured. Determine whether ENSG00000159399 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of HK2 is measured. Determine whether HK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1236
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor ENSG00000182871 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000182871 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor COL18A1 expression. Decide whether this perturbation leads to a significant alteration in COL18A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2328
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor ENSG00000169410 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000169410 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PTPN9 expression. Decide whether this perturbation leads to a significant alteration in PTPN9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2348
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of ENSG00000237330. Does perturbing RREB1 lead to a significant change in ENSG00000237330 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of RNF223. Does perturbing RREB1 lead to a significant change in RNF223 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2401
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ENSG00000162878 expression is measured. Determine whether ENSG00000162878 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and PKDCC expression is measured. Determine whether PKDCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":609
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ENSG00000268621 expression is quantified. Does this perturbation result in a significant change in ENSG00000268621 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2592
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ENSG00000099625 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of C19orf26 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":257
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000109099 is measured. Determine whether ENSG00000109099 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of PMP22 is measured. Determine whether PMP22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1196
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of ENSG00000185198. Does perturbing PTPN9 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PRSS57. Does perturbing PTPN9 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2361
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":273
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ENSG00000169442 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1957
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ENSG00000130303 expression is quantified. Does this perturbation result in a significant change in ENSG00000130303 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3032
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ENSG00000070214 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070214 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and SLC44A1 expression is observed. Does this perturbation lead to a significant difference in SLC44A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1173
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is quantified. Does this perturbation result in a significant change in ENSG00000079102 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is quantified. Does this perturbation result in a significant change in RUNX1T1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2442
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3113
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1403
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ENSG00000141744 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000141744 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1658
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ENSG00000260793. Does perturbing PLK4 lead to a significant change in ENSG00000260793 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP5-882C2.2. Does perturbing PLK4 lead to a significant change in RP5-882C2.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2141
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and ENSG00000206172 expression is observed. Does this perturbation lead to a significant difference in ENSG00000206172 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and HBA1 expression is observed. Does this perturbation lead to a significant difference in HBA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENSG00000106991 is measured. Determine whether ENSG00000106991 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of ENG is measured. Determine whether ENG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2316
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ENSG00000118777. Does perturbing ZBTB1 lead to a significant change in ENSG00000118777 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of ABCG2. Does perturbing ZBTB1 lead to a significant change in ABCG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3001
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and ENSG00000158517 expression is measured. Determine whether ENSG00000158517 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and NCF1 expression is measured. Determine whether NCF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":479
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of ENSG00000118058 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of KMT2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1687
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2574
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and ENSG00000104903 expression is observed. Does this perturbation lead to a significant difference in ENSG00000104903 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and LYL1 expression is observed. Does this perturbation lead to a significant difference in LYL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1743
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of ENSG00000227053. Does perturbing ZNF318 lead to a significant change in ENSG00000227053 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of RP11-395B7.4. Does perturbing ZNF318 lead to a significant change in RP11-395B7.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3121
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ENSG00000130656. Does perturbing MAP4K5 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of HBZ. Does perturbing MAP4K5 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1901
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ENSG00000130303 expression is measured. Determine whether ENSG00000130303 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3039
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of ENSG00000117139 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of KDM5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3147
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor ENSG00000102804 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000102804 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor TSC22D1 expression. Decide whether this perturbation leads to a significant alteration in TSC22D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":288
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":866
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ENSG00000166501 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2547
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ENSG00000142669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in SH3BGRL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":795
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ENSG00000170689. Does perturbing HOXB9 lead to a significant change in ENSG00000170689 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of HOXB9. Does perturbing HOXB9 lead to a significant change in HOXB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1321
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ENSG00000105939. Does perturbing ZC3HAV1 lead to a significant change in ENSG00000105939 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ZC3HAV1. Does perturbing ZC3HAV1 lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3091
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ENSG00000159556 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in ISL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1505
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ENSG00000166450 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000166450 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor PRTG expression. Decide whether this perturbation leads to a significant alteration in PRTG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2228
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ENSG00000206172. Does perturbing IKZF3 lead to a significant change in ENSG00000206172 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HBA1. Does perturbing IKZF3 lead to a significant change in HBA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1451
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ENSG00000115738 expression is observed. Does this perturbation lead to a significant difference in ENSG00000115738 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ID2 expression is observed. Does this perturbation lead to a significant difference in ID2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2013
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ENSG00000183770 is measured. Does this perturbation cause a significant change in ENSG00000183770 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of ENSG00000102804 is measured. Determine whether ENSG00000102804 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of TSC22D1 is measured. Determine whether TSC22D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2916
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of ENSG00000127831. Does perturbing LYL1 lead to a significant change in ENSG00000127831 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of VIL1. Does perturbing LYL1 lead to a significant change in VIL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1751
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ENSG00000141744. Does perturbing KLF1 lead to a significant change in ENSG00000141744 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of PNMT. Does perturbing KLF1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1661
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ENSG00000197766 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in CFD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2065
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of ENSG00000206172. Does perturbing S1PR2 lead to a significant change in ENSG00000206172 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of HBA1. Does perturbing S1PR2 lead to a significant change in HBA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2461
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of ENSG00000185198. Does this perturbation cause a significant change in ENSG00000185198 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2364
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ENSG00000143674 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000143674 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor KIAA1804 expression. Decide whether this perturbation leads to a significant alteration in KIAA1804 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1568
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in ENSG00000129757 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CDKN1C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":415
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ENSG00000177606. Does perturbing KIAA1804 lead to a significant change in ENSG00000177606 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of JUN. Does perturbing KIAA1804 lead to a significant change in JUN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1581
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of ENSG00000108821 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of COL1A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":727
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of ENSG00000188536 is measured. Determine whether ENSG00000188536 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of HBA2 is measured. Determine whether HBA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2476
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ENSG00000256713 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000256713 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PGA5 expression. Decide whether this perturbation leads to a significant alteration in PGA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":708
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of ENSG00000090382. Does perturbing FOXA3 lead to a significant change in ENSG00000090382 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LYZ. Does perturbing FOXA3 lead to a significant change in LYZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1051
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of ENSG00000129514. Does perturbing FOXA1 lead to a significant change in ENSG00000129514 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FOXA1. Does perturbing FOXA1 lead to a significant change in FOXA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1031
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ENSG00000206172. Does this perturbation cause a significant change in ENSG00000206172 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of HBA1. Does this perturbation cause a significant change in HBA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2274
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and ENSG00000129514 expression is measured. Determine whether ENSG00000129514 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FOXA1 expression is measured. Determine whether FOXA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1039
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":684
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ENSG00000159388 expression is measured. Determine whether ENSG00000159388 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1559
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ENSG00000002586 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in CD99 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":335
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":530
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of ENSG00000237330 is measured. Determine whether ENSG00000237330 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of RNF223 is measured. Determine whether RNF223 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2406
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2267
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in ENSG00000111057 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in KRT18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":195
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and ENSG00000070087 expression is quantified. Does this perturbation result in a significant change in ENSG00000070087 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and PFN2 expression is quantified. Does this perturbation result in a significant change in PFN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":502
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ENSG00000158578. Does perturbing IKZF3 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of ALAS2. Does perturbing IKZF3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1461
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and ENSG00000243449 expression is quantified. Does this perturbation result in a significant change in ENSG00000243449 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and C4orf48 expression is quantified. Does this perturbation result in a significant change in C4orf48 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":542
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ENSG00000143674. Does this perturbation cause a significant change in ENSG00000143674 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of KIAA1804. Does this perturbation cause a significant change in KIAA1804 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1564
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ENSG00000143369 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ECM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2307
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor ENSG00000070087 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000070087 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor PFN2 expression. Decide whether this perturbation leads to a significant alteration in PFN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":508
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2246
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ENSG00000142669. Does perturbing CSRNP1 lead to a significant change in ENSG00000142669 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of SH3BGRL3. Does perturbing CSRNP1 lead to a significant change in SH3BGRL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":791
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ENSG00000143401 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ANP32E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2085
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000144655 is measured. Does this perturbation cause a significant change in ENSG00000144655 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Does this perturbation cause a significant change in CSRNP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":780
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of ENSG00000135409 is measured. Does this perturbation cause a significant change in ENSG00000135409 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":220
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ENSG00000157557 expression is measured. Determine whether ENSG00000157557 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and ETS2 expression is measured. Determine whether ETS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":959
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ENSG00000256713. Does perturbing CNNM4 lead to a significant change in ENSG00000256713 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PGA5. Does perturbing CNNM4 lead to a significant change in PGA5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":701
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and ENSG00000153094 expression is quantified. Does this perturbation result in a significant change in ENSG00000153094 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and BCL2L11 expression is quantified. Does this perturbation result in a significant change in BCL2L11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":152
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in ENSG00000105223 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in PLD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1225
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of ENSG00000070087. Does this perturbation cause a significant change in ENSG00000070087 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of PFN2. Does this perturbation cause a significant change in PFN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":504
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and ENSG00000064886 expression is measured. Determine whether ENSG00000064886 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2429
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of ENSG00000030110 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":137
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and ENSG00000205277 expression is quantified. Does this perturbation result in a significant change in ENSG00000205277 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and MUC12 expression is quantified. Does this perturbation result in a significant change in MUC12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3132
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1073
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and ENSG00000163497 expression is quantified. Does this perturbation result in a significant change in ENSG00000163497 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1732
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000142669 is measured. Determine whether ENSG00000142669 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of SH3BGRL3 is measured. Determine whether SH3BGRL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":796
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of ENSG00000160185. Does perturbing UBASH3A lead to a significant change in ENSG00000160185 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2941
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in ENSG00000163499 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in CRYBA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":965
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor ENSG00000205277 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000205277 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor MUC12 expression. Decide whether this perturbation leads to a significant alteration in MUC12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3138
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ENSG00000158578. Does perturbing CBL lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ALAS2. Does perturbing CBL lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":351
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and ENSG00000188483 expression is measured. Determine whether ENSG00000188483 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and IER5L expression is measured. Determine whether IER5L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1389
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of ENSG00000258274. Does this perturbation cause a significant change in ENSG00000258274 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of RP11-887P2.5. Does this perturbation cause a significant change in RP11-887P2.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1364
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of ENSG00000119535 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":587
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of ENSG00000204482 is measured. Does this perturbation cause a significant change in ENSG00000204482 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":450
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2594
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":452
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":537
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ENSG00000108984 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000108984 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor MAP2K6 expression. Decide whether this perturbation leads to a significant alteration in MAP2K6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1838
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ENSG00000143162 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CREG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1597
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in ENSG00000030110 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":135
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ENSG00000116871 expression is quantified. Does this perturbation result in a significant change in ENSG00000116871 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1932
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ENSG00000134294 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of SLC38A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2587
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of ENSG00000102804 is measured. Determine whether ENSG00000102804 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of TSC22D1 is measured. Determine whether TSC22D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":286
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ENSG00000177606 expression is quantified. Does this perturbation result in a significant change in ENSG00000177606 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and JUN expression is quantified. Does this perturbation result in a significant change in JUN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1542
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ENSG00000142669. Does this perturbation cause a significant change in ENSG00000142669 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of SH3BGRL3. Does this perturbation cause a significant change in SH3BGRL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1014
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ENSG00000135047 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000135047 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1888
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":342
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":872
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of ENSG00000101200. Does this perturbation cause a significant change in ENSG00000101200 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2804
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of ENSG00000185198. Does perturbing SAMD1 lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of PRSS57. Does perturbing SAMD1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2511
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of ENSG00000153012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of LGI2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":497
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ENSG00000140545 is measured. Determine whether ENSG00000140545 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":616
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of ENSG00000163497. Does this perturbation cause a significant change in ENSG00000163497 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1734
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and ENSG00000160185 expression is measured. Determine whether ENSG00000160185 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2949
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ENSG00000143369 expression is observed. Does this perturbation lead to a significant difference in ENSG00000143369 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ECM1 expression is observed. Does this perturbation lead to a significant difference in ECM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2303
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is measured. Determine whether ENSG00000099625 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and C19orf26 expression is measured. Determine whether C19orf26 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":259
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ENSG00000130656. Does perturbing CBL lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of HBZ. Does perturbing CBL lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":341
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in ENSG00000108821 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in COL1A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":725
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ENSG00000077063 expression is quantified. Does this perturbation result in a significant change in ENSG00000077063 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CTTNBP2 expression is quantified. Does this perturbation result in a significant change in CTTNBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1612
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ENSG00000075624 expression is quantified. Does this perturbation result in a significant change in ENSG00000075624 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ACTB expression is quantified. Does this perturbation result in a significant change in ACTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2862
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ENSG00000099625. Does perturbing C19orf26 lead to a significant change in ENSG00000099625 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of C19orf26. Does perturbing C19orf26 lead to a significant change in C19orf26 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":241
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor ENSG00000101200 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000101200 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2888
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ENSG00000158869 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158869 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3058
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in ENSG00000250361 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in GYPB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":165
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ENSG00000183770 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000183770 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1128
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in ENSG00000085185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in BCORL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":185
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2198
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ENSG00000099625 expression is quantified. Does this perturbation result in a significant change in ENSG00000099625 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and C19orf26 expression is quantified. Does this perturbation result in a significant change in C19orf26 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":242
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000117091 is measured. Does this perturbation cause a significant change in ENSG00000117091 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of CD48 is measured. Does this perturbation cause a significant change in CD48 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1300
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000005187 is measured. Does this perturbation cause a significant change in ENSG00000005187 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ACSM3 is measured. Does this perturbation cause a significant change in ACSM3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":900
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ENSG00000158869 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3055
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ENSG00000115758 expression is quantified. Does this perturbation result in a significant change in ENSG00000115758 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ODC1 expression is quantified. Does this perturbation result in a significant change in ODC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2414
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of ENSG00000184481. Does perturbing FOXO4 lead to a significant change in ENSG00000184481 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of FOXO4. Does perturbing FOXO4 lead to a significant change in FOXO4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1141
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1874
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":387
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1008
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":536
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of ENSG00000196188. Does this perturbation cause a significant change in ENSG00000196188 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CTSE. Does this perturbation cause a significant change in CTSE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1274
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of ENSG00000172331 is measured. Determine whether ENSG00000172331 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of BPGM is measured. Determine whether BPGM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":216
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2699
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in ENSG00000070214 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in SLC44A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3015
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1076
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in ENSG00000185198 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1995
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of ENSG00000258274 is measured. Determine whether ENSG00000258274 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of RP11-887P2.5 is measured. Determine whether RP11-887P2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1356
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":877
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of ENSG00000127831 is measured. Determine whether ENSG00000127831 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of VIL1 is measured. Determine whether VIL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1756
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000034152 is measured. Does this perturbation cause a significant change in ENSG00000034152 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of MAP2K3 is measured. Does this perturbation cause a significant change in MAP2K3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1800
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is quantified. Does this perturbation result in a significant change in ENSG00000170689 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and HOXB9 expression is quantified. Does this perturbation result in a significant change in HOXB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1322
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of ENSG00000142945. Does this perturbation cause a significant change in ENSG00000142945 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1634
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ENSG00000158578 expression is measured. Determine whether ENSG00000158578 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":659
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in ENSG00000127831 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in VIL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1755
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ENSG00000109099 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000109099 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor PMP22 expression. Decide whether this perturbation leads to a significant alteration in PMP22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1198
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of ENSG00000273706 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1717
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of ENSG00000141753 is measured. Determine whether ENSG00000141753 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of IGFBP4 is measured. Determine whether IGFBP4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2966
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of ENSG00000127831 is measured. Does this perturbation cause a significant change in ENSG00000127831 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of VIL1 is measured. Does this perturbation cause a significant change in VIL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1750
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor ENSG00000204482 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000204482 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":538
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ENSG00000064886 is measured. Determine whether ENSG00000064886 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1816
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and ENSG00000121900 expression is measured. Determine whether ENSG00000121900 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and TMEM54 expression is measured. Determine whether TMEM54 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2769
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor ENSG00000273706 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000273706 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1718
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of ENSG00000163513 is measured. Determine whether ENSG00000163513 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of TGFBR2 is measured. Determine whether TGFBR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2836
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ENSG00000186185 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in KIF18B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1605
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ENSG00000163520 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163520 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor FBLN2 expression. Decide whether this perturbation leads to a significant alteration in FBLN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1188
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ENSG00000156030 is measured. Does this perturbation cause a significant change in ENSG00000156030 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ELMSAN1 is measured. Does this perturbation cause a significant change in ELMSAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":910
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of ENSG00000092621 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":747
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ENSG00000079102 expression is measured. Determine whether ENSG00000079102 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and RUNX1T1 expression is measured. Determine whether RUNX1T1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2449
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and ENSG00000185198 expression is measured. Determine whether ENSG00000185198 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2369
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor ENSG00000153094 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000153094 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor BCL2L11 expression. Decide whether this perturbation leads to a significant alteration in BCL2L11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":158
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of ENSG00000166340 is measured. Determine whether ENSG00000166340 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of TPP1 is measured. Determine whether TPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1156
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of ENSG00000258274. Does perturbing HOXC13 lead to a significant change in ENSG00000258274 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of RP11-887P2.5. Does perturbing HOXC13 lead to a significant change in RP11-887P2.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1351
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ENSG00000159388. Does this perturbation cause a significant change in ENSG00000159388 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1554
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ENSG00000109099. Does perturbing GLB1L2 lead to a significant change in ENSG00000109099 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of PMP22. Does perturbing GLB1L2 lead to a significant change in PMP22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1191
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ENSG00000130176. Does perturbing CNN1 lead to a significant change in ENSG00000130176 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CNN1. Does perturbing CNN1 lead to a significant change in CNN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":671
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in ENSG00000142945 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1625
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of ENSG00000069482. Does perturbing EGR1 lead to a significant change in ENSG00000069482 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of GAL. Does perturbing EGR1 lead to a significant change in GAL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":891
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ENSG00000170689 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170689 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and HOXB9 expression is observed. Does this perturbation lead to a significant difference in HOXB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1333
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2243
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ENSG00000130176 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130176 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CNN1 expression is observed. Does this perturbation lead to a significant difference in CNN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":673
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of ENSG00000169442. Does perturbing EGR1 lead to a significant change in ENSG00000169442 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CD52. Does perturbing EGR1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":881
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1893
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of ENSG00000204472 is measured. Does this perturbation cause a significant change in ENSG00000204472 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":940
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ENSG00000115255. Does perturbing CKS1B lead to a significant change in ENSG00000115255 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of REEP6. Does perturbing CKS1B lead to a significant change in REEP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":621
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and ENSG00000172331 expression is observed. Does this perturbation lead to a significant difference in ENSG00000172331 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and BPGM expression is observed. Does this perturbation lead to a significant difference in BPGM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":213
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ENSG00000104894 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in CD37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":775
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ENSG00000113594. Does this perturbation cause a significant change in ENSG00000113594 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of LIFR. Does this perturbation cause a significant change in LIFR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1794
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of ENSG00000127831 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of VIL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1757
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":232
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of ENSG00000265972 is measured. Does this perturbation cause a significant change in ENSG00000265972 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1240
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ENSG00000116871 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1925
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and ENSG00000160838 expression is observed. Does this perturbation lead to a significant difference in ENSG00000160838 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and LRRC71 expression is observed. Does this perturbation lead to a significant difference in LRRC71 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ENSG00000115738. Does this perturbation cause a significant change in ENSG00000115738 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ID2. Does this perturbation cause a significant change in ID2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2014
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Does this perturbation cause a significant change in ENSG00000130176 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Does this perturbation cause a significant change in CNN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":670
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ENSG00000139219 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000139219 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor COL2A1 expression. Decide whether this perturbation leads to a significant alteration in COL2A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":758
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1007
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ENSG00000258274 is measured. Determine whether ENSG00000258274 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of RP11-887P2.5 is measured. Determine whether RP11-887P2.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1316
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ENSG00000142669 expression is quantified. Does this perturbation result in a significant change in ENSG00000142669 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and SH3BGRL3 expression is quantified. Does this perturbation result in a significant change in SH3BGRL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1012
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ENSG00000279669 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in RP11-717F1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2675
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of ENSG00000196188 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CTSE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1277
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1898
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ENSG00000157557 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000157557 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor ETS2 expression. Decide whether this perturbation leads to a significant alteration in ETS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":958
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of ENSG00000169410 is measured. Does this perturbation cause a significant change in ENSG00000169410 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PTPN9 is measured. Does this perturbation cause a significant change in PTPN9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2350
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor ENSG00000227053 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000227053 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor RP11-395B7.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-395B7.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3128
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ENSG00000279576 expression is observed. Does this perturbation lead to a significant difference in ENSG00000279576 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and AP000769.1 expression is observed. Does this perturbation lead to a significant difference in AP000769.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1943
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and ENSG00000130656 expression is quantified. Does this perturbation result in a significant change in ENSG00000130656 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and HBZ expression is quantified. Does this perturbation result in a significant change in HBZ expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2412
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ENSG00000166450 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of PRTG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2227
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ENSG00000099625 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000099625 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor C19orf26 expression. Decide whether this perturbation leads to a significant alteration in C19orf26 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":258
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of ENSG00000090382 is measured. Determine whether ENSG00000090382 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LYZ is measured. Determine whether LYZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1056
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ENSG00000116871 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1935
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ENSG00000170689 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in HOXB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1335
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ENSG00000130656. Does perturbing PTPN1 lead to a significant change in ENSG00000130656 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of HBZ. Does perturbing PTPN1 lead to a significant change in HBZ expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2251
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ENSG00000099625 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in C19orf26 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":245
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2196
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and ENSG00000277268 expression is measured. Determine whether ENSG00000277268 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and RP11-445F12.1 expression is measured. Determine whether RP11-445F12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1729
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ENSG00000100097 is measured. Does this perturbation cause a significant change in ENSG00000100097 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":800
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ENSG00000103241 expression is measured. Determine whether ENSG00000103241 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1099
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and ENSG00000258274 expression is measured. Determine whether ENSG00000258274 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and RP11-887P2.5 expression is measured. Determine whether RP11-887P2.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1369
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2073
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in ENSG00000159399 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in HK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1235
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of ENSG00000250361 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of GYPB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":167
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":427
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and ENSG00000119535 expression is measured. Determine whether ENSG00000119535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":469
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ENSG00000204482 is measured. Determine whether ENSG00000204482 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2716
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ENSG00000109099. Does this perturbation cause a significant change in ENSG00000109099 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of PMP22. Does this perturbation cause a significant change in PMP22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1194
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of ENSG00000174498 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1427
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ENSG00000115758 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ODC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ENSG00000005187 expression is observed. Does this perturbation lead to a significant difference in ENSG00000005187 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ACSM3 expression is observed. Does this perturbation lead to a significant difference in ACSM3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1573
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and ENSG00000184697 expression is observed. Does this perturbation lead to a significant difference in ENSG00000184697 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CLDN6 expression is observed. Does this perturbation lead to a significant difference in CLDN6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":643
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in ENSG00000105697 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in HAMP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2485
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ENSG00000130656 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000130656 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor HBZ expression. Decide whether this perturbation leads to a significant alteration in HBZ expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":688
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ENSG00000204482 expression is quantified. Does this perturbation result in a significant change in ENSG00000204482 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2702
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ENSG00000077063 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in CTTNBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of ENSG00000185198. Does perturbing ARID1A lead to a significant change in ENSG00000185198 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of PRSS57. Does perturbing ARID1A lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2416
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ENSG00000134294 expression is observed. Does this perturbation lead to a significant difference in ENSG00000134294 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and SLC38A2 expression is observed. Does this perturbation lead to a significant difference in SLC38A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2583
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of ENSG00000101200 is measured. Does this perturbation cause a significant change in ENSG00000101200 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2880
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ENSG00000034152 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of MAP2K3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1807
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ENSG00000158578 is measured. Does this perturbation cause a significant change in ENSG00000158578 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1460
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ENSG00000189171 expression is observed. Does this perturbation lead to a significant difference in ENSG00000189171 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3043
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2374
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ENSG00000189171 expression is measured. Determine whether ENSG00000189171 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2079
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ENSG00000002586. Does this perturbation cause a significant change in ENSG00000002586 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of CD99. Does this perturbation cause a significant change in CD99 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":334
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and ENSG00000205542 expression is quantified. Does this perturbation result in a significant change in ENSG00000205542 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TMSB4X expression is quantified. Does this perturbation result in a significant change in TMSB4X expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2852
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of ENSG00000142945. Does perturbing KIF2C lead to a significant change in ENSG00000142945 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1621
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and ENSG00000184697 expression is measured. Determine whether ENSG00000184697 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CLDN6 expression is measured. Determine whether CLDN6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":639
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ENSG00000141744 is measured. Determine whether ENSG00000141744 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1656
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and ENSG00000196517 expression is quantified. Does this perturbation result in a significant change in ENSG00000196517 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and SLC6A9 expression is quantified. Does this perturbation result in a significant change in SLC6A9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2642
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ENSG00000163520 is measured. Determine whether ENSG00000163520 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of FBLN2 is measured. Determine whether FBLN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1186
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of ENSG00000135111 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of TBX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ENSG00000206172 expression is quantified. Does this perturbation result in a significant change in ENSG00000206172 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and HBA1 expression is quantified. Does this perturbation result in a significant change in HBA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2272
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of ENSG00000104903 is measured. Does this perturbation cause a significant change in ENSG00000104903 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of LYL1 is measured. Does this perturbation cause a significant change in LYL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1740
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of ENSG00000153094 is measured. Determine whether ENSG00000153094 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Determine whether BCL2L11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":156
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ENSG00000149516 expression is quantified. Does this perturbation result in a significant change in ENSG00000149516 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and MS4A3 expression is quantified. Does this perturbation result in a significant change in MS4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":992
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and ENSG00000164920 expression is measured. Determine whether ENSG00000164920 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and OSR2 expression is measured. Determine whether OSR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2109
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ENSG00000213934 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of HBG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":327
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in ENSG00000069011 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in PITX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1215
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and ENSG00000070214 expression is observed. Does this perturbation lead to a significant difference in ENSG00000070214 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and SLC44A1 expression is observed. Does this perturbation lead to a significant difference in SLC44A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3023
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ENSG00000159388 is measured. Does this perturbation cause a significant change in ENSG00000159388 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1550
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ENSG00000135047 expression is measured. Determine whether ENSG00000135047 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2609
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ENSG00000124762. Does perturbing CDKN1A lead to a significant change in ENSG00000124762 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CDKN1A. Does perturbing CDKN1A lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":371
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ENSG00000170689 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in HOXB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1325
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in ENSG00000272211 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in RP11-347P5.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1705
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2385
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and ENSG00000101200 expression is quantified. Does this perturbation result in a significant change in ENSG00000101200 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2882
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ENSG00000166450 expression is quantified. Does this perturbation result in a significant change in ENSG00000166450 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and PRTG expression is quantified. Does this perturbation result in a significant change in PRTG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2232
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of ENSG00000247516. Does perturbing ZBTB25 lead to a significant change in ENSG00000247516 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of MIR4458HG. Does perturbing ZBTB25 lead to a significant change in MIR4458HG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3081
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and ENSG00000163513 expression is quantified. Does this perturbation result in a significant change in ENSG00000163513 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and TGFBR2 expression is quantified. Does this perturbation result in a significant change in TGFBR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2832
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of ENSG00000162493 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PDPN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2627
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and ENSG00000070214 expression is measured. Determine whether ENSG00000070214 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and SLC44A1 expression is measured. Determine whether SLC44A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3029
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ENSG00000130656. Does this perturbation cause a significant change in ENSG00000130656 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of HBZ. Does this perturbation cause a significant change in HBZ expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1904
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and ENSG00000205542 expression is observed. Does this perturbation lead to a significant difference in ENSG00000205542 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TMSB4X expression is observed. Does this perturbation lead to a significant difference in TMSB4X expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2853
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130176 is measured. Determine whether ENSG00000130176 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CNN1 is measured. Determine whether CNN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":676
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ENSG00000103241. Does this perturbation cause a significant change in ENSG00000103241 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1084
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in ENSG00000129514 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FOXA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1035
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ENSG00000279669 expression is measured. Determine whether ENSG00000279669 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and RP11-717F1.1 expression is measured. Determine whether RP11-717F1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2679
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ENSG00000115738 is measured. Determine whether ENSG00000115738 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ID2 is measured. Determine whether ID2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2016
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and ENSG00000153094 expression is observed. Does this perturbation lead to a significant difference in ENSG00000153094 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and BCL2L11 expression is observed. Does this perturbation lead to a significant difference in BCL2L11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":153
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ENSG00000166450 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in PRTG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2235
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of ENSG00000124762. Does perturbing CDKN1A lead to a significant change in ENSG00000124762 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CDKN1A. Does perturbing CDKN1A lead to a significant change in CDKN1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":361
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ENSG00000158578 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000158578 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2848
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ENSG00000069482 expression is measured. Determine whether ENSG00000069482 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and GAL expression is measured. Determine whether GAL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1139
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of ENSG00000188483 is measured. Determine whether ENSG00000188483 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of IER5L is measured. Determine whether IER5L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1386
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in ENSG00000203989 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in RHOXF2BB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2755
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in ENSG00000247516 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in MIR4458HG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3085
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of ENSG00000115844 is measured. Determine whether ENSG00000115844 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of DLX2 is measured. Determine whether DLX2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":816
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1896
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENSG00000106991 expression is quantified. Does this perturbation result in a significant change in ENSG00000106991 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and ENG expression is quantified. Does this perturbation result in a significant change in ENG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2312
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in ENSG00000240065 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in PSMB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1485
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor ENSG00000127831 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000127831 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor VIL1 expression. Decide whether this perturbation leads to a significant alteration in VIL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1758
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ENSG00000158578 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ENSG00000177606 is measured. Determine whether ENSG00000177606 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of JUN is measured. Determine whether JUN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1546
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Does this perturbation cause a significant change in ENSG00000196565 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Does this perturbation cause a significant change in HBG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":310
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ENSG00000129757 is measured. Does this perturbation cause a significant change in ENSG00000129757 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CDKN1C is measured. Does this perturbation cause a significant change in CDKN1C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":440
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in ENSG00000119535 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":465
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ENSG00000142669 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000142669 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor SH3BGRL3 expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1018
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ENSG00000157557. Does this perturbation cause a significant change in ENSG00000157557 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of ETS2. Does this perturbation cause a significant change in ETS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":954
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and ENSG00000071967 expression is quantified. Does this perturbation result in a significant change in ENSG00000071967 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and CYBRD1 expression is quantified. Does this perturbation result in a significant change in CYBRD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1492
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ENSG00000163520 expression is quantified. Does this perturbation result in a significant change in ENSG00000163520 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and FBLN2 expression is quantified. Does this perturbation result in a significant change in FBLN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1182
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and ENSG00000030110 expression is measured. Determine whether ENSG00000030110 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":139
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ENSG00000260793 expression is measured. Determine whether ENSG00000260793 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP5-882C2.2 expression is measured. Determine whether RP5-882C2.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2149
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of ENSG00000092621 is measured. Does this perturbation cause a significant change in ENSG00000092621 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":740
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ENSG00000279576. Does perturbing MAP7D1 lead to a significant change in ENSG00000279576 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of AP000769.1. Does perturbing MAP7D1 lead to a significant change in AP000769.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1941
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ENSG00000170689 is measured. Determine whether ENSG00000170689 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of HOXB9 is measured. Determine whether HOXB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1336
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ENSG00000279576 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000279576 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor AP000769.1 expression. Decide whether this perturbation leads to a significant alteration in AP000769.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1948
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of ENSG00000135409 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":227
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and ENSG00000164920 expression is measured. Determine whether ENSG00000164920 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and OSR2 expression is measured. Determine whether OSR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2119
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and ENSG00000185198 expression is observed. Does this perturbation lead to a significant difference in ENSG00000185198 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2363
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ENSG00000133317 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of LGALS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2457
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ENSG00000169413 expression is observed. Does this perturbation lead to a significant difference in ENSG00000169413 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and RNASE6 expression is observed. Does this perturbation lead to a significant difference in RNASE6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1913
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of ENSG00000247516 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of MIR4458HG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3067
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and ENSG00000162493 expression is measured. Determine whether ENSG00000162493 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PDPN expression is measured. Determine whether PDPN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2629
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ENSG00000115758 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000115758 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ODC1 expression. Decide whether this perturbation leads to a significant alteration in ODC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor ENSG00000185198 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000185198 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ENSG00000075624 expression is measured. Determine whether ENSG00000075624 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and ACTB expression is measured. Determine whether ACTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2869
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ENSG00000189171 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2077
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ENSG00000170689. Does perturbing HOXB9 lead to a significant change in ENSG00000170689 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of HOXB9. Does perturbing HOXB9 lead to a significant change in HOXB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1331
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of ENSG00000160838. Does perturbing ARID1A lead to a significant change in ENSG00000160838 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of LRRC71. Does perturbing ARID1A lead to a significant change in LRRC71 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2253
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of ENSG00000064886. Does this perturbation cause a significant change in ENSG00000064886 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2424
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of ENSG00000164920 is measured. Does this perturbation cause a significant change in ENSG00000164920 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of OSR2 is measured. Does this perturbation cause a significant change in OSR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2100
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ENSG00000077063 is measured. Does this perturbation cause a significant change in ENSG00000077063 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of CTTNBP2 is measured. Does this perturbation cause a significant change in CTTNBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of ENSG00000142945 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1627
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2653
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in ENSG00000163531 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in NFASC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1765
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of ENSG00000265972 is measured. Determine whether ENSG00000265972 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1246
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENSG00000106991 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in ENG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2315
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in ENSG00000205542 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TMSB4X expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2855
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1987
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and ENSG00000130656 expression is measured. Determine whether ENSG00000130656 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HBZ expression is measured. Determine whether HBZ exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2499
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ENSG00000116871 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1937
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ENSG00000168140 is measured. Determine whether ENSG00000168140 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of VASN is measured. Determine whether VASN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2026
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ENSG00000005187 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000005187 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ACSM3 expression. Decide whether this perturbation leads to a significant alteration in ACSM3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":928
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of ENSG00000172331. Does perturbing BPGM lead to a significant change in ENSG00000172331 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of BPGM. Does perturbing BPGM lead to a significant change in BPGM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":211
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ENSG00000231312. Does perturbing MAP4K3 lead to a significant change in ENSG00000231312 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AC007246.3. Does perturbing MAP4K3 lead to a significant change in AC007246.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1861
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ENSG00000135047 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2607
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ENSG00000256713 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PGA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":707
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and ENSG00000119535 expression is quantified. Does this perturbation result in a significant change in ENSG00000119535 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":462
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ENSG00000077063 expression is measured. Determine whether ENSG00000077063 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and CTTNBP2 expression is measured. Determine whether CTTNBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ENSG00000069535 expression is measured. Determine whether ENSG00000069535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and MAOB expression is measured. Determine whether MAOB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1539
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ENSG00000105610 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of KLF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1677
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and ENSG00000183019 expression is quantified. Does this perturbation result in a significant change in ENSG00000183019 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and MCEMP1 expression is quantified. Does this perturbation result in a significant change in MCEMP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":172
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ENSG00000130176 expression is measured. Determine whether ENSG00000130176 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CNN1 expression is measured. Determine whether CNN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":679
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Does this perturbation cause a significant change in ENSG00000103241 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1080
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of ENSG00000085185. Does this perturbation cause a significant change in ENSG00000085185 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of BCORL1. Does this perturbation cause a significant change in BCORL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":184
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and ENSG00000111057 expression is quantified. Does this perturbation result in a significant change in ENSG00000111057 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and KRT18 expression is quantified. Does this perturbation result in a significant change in KRT18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":192
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of ENSG00000172331 is measured. Does this perturbation cause a significant change in ENSG00000172331 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of BPGM is measured. Does this perturbation cause a significant change in BPGM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":210
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ENSG00000158578 is measured. Determine whether ENSG00000158578 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":406
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and ENSG00000085185 expression is observed. Does this perturbation lead to a significant difference in ENSG00000085185 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and BCORL1 expression is observed. Does this perturbation lead to a significant difference in BCORL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":183
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ENSG00000204482 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2717
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ENSG00000279669 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of RP11-717F1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2677
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor ENSG00000163497 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000163497 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":978
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor ENSG00000004939 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000004939 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor SLC4A1 expression. Decide whether this perturbation leads to a significant alteration in SLC4A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2638
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ENSG00000170542 is measured. Does this perturbation cause a significant change in ENSG00000170542 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of SERPINB9 is measured. Does this perturbation cause a significant change in SERPINB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2530
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ENSG00000158578 expression is observed. Does this perturbation lead to a significant difference in ENSG00000158578 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":423
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ENSG00000268621. Does this perturbation cause a significant change in ENSG00000268621 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in ENSG00000130656 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in HBZ expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2215
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and ENSG00000247516 expression is quantified. Does this perturbation result in a significant change in ENSG00000247516 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and MIR4458HG expression is quantified. Does this perturbation result in a significant change in MIR4458HG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3062
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ENSG00000118515 is measured. Determine whether ENSG00000118515 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of SGK1 is measured. Determine whether SGK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2556
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ENSG00000069482 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in GAL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1135
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ENSG00000260793 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000260793 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP5-882C2.2 expression. Decide whether this perturbation leads to a significant alteration in RP5-882C2.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2148
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ENSG00000268621 expression is observed. Does this perturbation lead to a significant difference in ENSG00000268621 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2593
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and ENSG00000255346 expression is measured. Determine whether ENSG00000255346 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and NOX5 expression is measured. Determine whether NOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2899
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of ENSG00000064886 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2427
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and ENSG00000227053 expression is observed. Does this perturbation lead to a significant difference in ENSG00000227053 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and RP11-395B7.4 expression is observed. Does this perturbation lead to a significant difference in RP11-395B7.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3123
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and ENSG00000170608 expression is observed. Does this perturbation lead to a significant difference in ENSG00000170608 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and FOXA3 expression is observed. Does this perturbation lead to a significant difference in FOXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1063
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ENSG00000158869 expression is quantified. Does this perturbation result in a significant change in ENSG00000158869 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3052
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ENSG00000105939 is measured. Determine whether ENSG00000105939 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3096
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of ENSG00000247516 is measured. Determine whether ENSG00000247516 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of MIR4458HG is measured. Determine whether MIR4458HG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3066
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of ENSG00000185198 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1997
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and ENSG00000119535 expression is measured. Determine whether ENSG00000119535 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":589
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ENSG00000130656 expression is observed. Does this perturbation lead to a significant difference in ENSG00000130656 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and HBZ expression is observed. Does this perturbation lead to a significant difference in HBZ expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ENSG00000128016 is measured. Determine whether ENSG00000128016 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ZFP36 is measured. Determine whether ZFP36 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2056
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and ENSG00000154127 expression is measured. Determine whether ENSG00000154127 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2989
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and ENSG00000124762 expression is measured. Determine whether ENSG00000124762 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CDKN1A expression is measured. Determine whether CDKN1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":379
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of ENSG00000184697. Does this perturbation cause a significant change in ENSG00000184697 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CLDN6. Does this perturbation cause a significant change in CLDN6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":644
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ENSG00000205542. Does this perturbation cause a significant change in ENSG00000205542 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TMSB4X. Does this perturbation cause a significant change in TMSB4X expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2854
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in ENSG00000196565 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in HBG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2395
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ENSG00000011600 is measured. Does this perturbation cause a significant change in ENSG00000011600 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2720
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in ENSG00000162493 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PDPN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2625
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ENSG00000170689 expression is measured. Determine whether ENSG00000170689 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and HOXB9 expression is measured. Determine whether HOXB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1339
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and ENSG00000069482 expression is observed. Does this perturbation lead to a significant difference in ENSG00000069482 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and GAL expression is observed. Does this perturbation lead to a significant difference in GAL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":893
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ENSG00000279576 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in AP000769.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1945
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and ENSG00000240065 expression is quantified. Does this perturbation result in a significant change in ENSG00000240065 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and PSMB9 expression is quantified. Does this perturbation result in a significant change in PSMB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1482
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor ENSG00000069011 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000069011 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor PITX1 expression. Decide whether this perturbation leads to a significant alteration in PITX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1218
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ENSG00000279669 expression is observed. Does this perturbation lead to a significant difference in ENSG00000279669 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and RP11-717F1.1 expression is observed. Does this perturbation lead to a significant difference in RP11-717F1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2673
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of ENSG00000160838 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of LRRC71 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of ENSG00000111057. Does perturbing BCORL1 lead to a significant change in ENSG00000111057 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of KRT18. Does perturbing BCORL1 lead to a significant change in KRT18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":191
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of ENSG00000030110 is measured. Does this perturbation cause a significant change in ENSG00000030110 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":140
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":680
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of ENSG00000092067 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CEBPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":527
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ENSG00000158578. Does perturbing SNAI1 lead to a significant change in ENSG00000158578 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ALAS2. Does perturbing SNAI1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2681
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ENSG00000075624. Does this perturbation cause a significant change in ENSG00000075624 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of ACTB. Does this perturbation cause a significant change in ACTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2864
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of ENSG00000245532 is measured. Does this perturbation cause a significant change in ENSG00000245532 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of NEAT1 is measured. Does this perturbation cause a significant change in NEAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":590
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ENSG00000177606 expression is measured. Determine whether ENSG00000177606 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and JUN expression is measured. Determine whether JUN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1549
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ENSG00000177606 expression is observed. Does this perturbation lead to a significant difference in ENSG00000177606 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and JUN expression is observed. Does this perturbation lead to a significant difference in JUN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1583
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ENSG00000196565 is measured. Determine whether ENSG00000196565 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of HBG2 is measured. Determine whether HBG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":306
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ENSG00000130656 is measured. Determine whether ENSG00000130656 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of HBZ is measured. Determine whether HBZ shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2286
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ENSG00000103241 is measured. Determine whether ENSG00000103241 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1086
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ENSG00000130656 is measured. Does this perturbation cause a significant change in ENSG00000130656 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of HBZ is measured. Does this perturbation cause a significant change in HBZ expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":340
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ENSG00000130656 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of HBZ indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2297
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ENSG00000114315 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in HES1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2035
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ENSG00000158578 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1075
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and ENSG00000188536 expression is quantified. Does this perturbation result in a significant change in ENSG00000188536 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and HBA2 expression is quantified. Does this perturbation result in a significant change in HBA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2472
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ENSG00000077063 expression is quantified. Does this perturbation result in a significant change in ENSG00000077063 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and CTTNBP2 expression is quantified. Does this perturbation result in a significant change in CTTNBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor ENSG00000026297 expression. Decide whether this perturbation leads to a significant alteration in ENSG00000026297 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor RNASET2 expression. Decide whether this perturbation leads to a significant alteration in RNASET2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":838
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ENSG00000140545. Does this perturbation cause a significant change in ENSG00000140545 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":614
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ENSG00000158578. Does this perturbation cause a significant change in ENSG00000158578 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2244
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ENSG00000118777 is measured. Does this perturbation cause a significant change in ENSG00000118777 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of ABCG2 is measured. Does this perturbation cause a significant change in ABCG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3000
  }
]