,question,answer,question_new 1097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4408,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CDK1 expression. Decide whether this perturbation leads to a significant alteration in CDK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CDK1 expression. Decide whether this perturbation leads to a significant alteration in CDK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SKAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SKAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-1017G21.6. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-1017G21.6. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Determine whether RLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Determine whether RLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5613,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01358 expression is observed. Does this perturbation lead to a significant difference in LINC01358 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01358 expression is observed. Does this perturbation lead to a significant difference in LINC01358 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in RABAC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in RABAC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of LMNA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of LMNA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1688,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor LMNA expression. Decide whether this perturbation leads to a significant alteration in LMNA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor LMNA expression. Decide whether this perturbation leads to a significant alteration in LMNA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2710,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Does this perturbation cause a significant change in TUBA1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Does this perturbation cause a significant change in TUBA1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and MKNK2 expression is quantified. Does this perturbation result in a significant change in MKNK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and MKNK2 expression is quantified. Does this perturbation result in a significant change in MKNK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4828,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of SLC38A2. Does this perturbation cause a significant change in SLC38A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of SLC38A2. Does this perturbation cause a significant change in SLC38A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 38,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor PDE1B expression. Decide whether this perturbation leads to a significant alteration in PDE1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor PDE1B expression. Decide whether this perturbation leads to a significant alteration in PDE1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in TAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in TAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2163,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and SPTAN1 expression is observed. Does this perturbation lead to a significant difference in SPTAN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and SPTAN1 expression is observed. Does this perturbation lead to a significant difference in SPTAN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 278,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor STAC3 expression. Decide whether this perturbation leads to a significant alteration in STAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor STAC3 expression. Decide whether this perturbation leads to a significant alteration in STAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ARMCX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ARMCX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3153,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in VCX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in VCX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2913,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and H1FNT expression is observed. Does this perturbation lead to a significant difference in H1FNT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and H1FNT expression is observed. Does this perturbation lead to a significant difference in H1FNT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2223,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2890,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Does this perturbation cause a significant change in FAM46C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Does this perturbation cause a significant change in FAM46C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD47. Does perturbing ETS2 lead to a significant change in CD47 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD47. Does perturbing ETS2 lead to a significant change in CD47 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of DLX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of DLX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of RP11-452C8.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of RP11-452C8.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and TAC3 expression is measured. Determine whether TAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and TAC3 expression is measured. Determine whether TAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2453,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and RETN expression is observed. Does this perturbation lead to a significant difference in RETN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and RETN expression is observed. Does this perturbation lead to a significant difference in RETN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4493,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and TTC9B expression is observed. Does this perturbation lead to a significant difference in TTC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and TTC9B expression is observed. Does this perturbation lead to a significant difference in TTC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5303,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PPFIA4 expression is observed. Does this perturbation lead to a significant difference in PPFIA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PPFIA4 expression is observed. Does this perturbation lead to a significant difference in PPFIA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3110,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Does this perturbation cause a significant change in AC145110.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Does this perturbation cause a significant change in AC145110.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and AGXT expression is measured. Determine whether AGXT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and AGXT expression is measured. Determine whether AGXT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TMEM55A. Does perturbing KIF2C lead to a significant change in TMEM55A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TMEM55A. Does perturbing KIF2C lead to a significant change in TMEM55A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of KRTAP9-9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of KRTAP9-9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5150,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of SERPINF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of SERPINF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3638,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ATG2A expression. Decide whether this perturbation leads to a significant alteration in ATG2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ATG2A expression. Decide whether this perturbation leads to a significant alteration in ATG2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and PTPRS expression is quantified. Does this perturbation result in a significant change in PTPRS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and PTPRS expression is quantified. Does this perturbation result in a significant change in PTPRS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3320,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and AC139099.6 expression is quantified. Does this perturbation result in a significant change in AC139099.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and AC139099.6 expression is quantified. Does this perturbation result in a significant change in AC139099.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Determine whether HCN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Determine whether HCN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1823,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2788,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of LBH. Does this perturbation cause a significant change in LBH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of LBH. Does this perturbation cause a significant change in LBH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and HEATR9 expression is measured. Determine whether HEATR9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and HEATR9 expression is measured. Determine whether HEATR9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of AK8. Does this perturbation cause a significant change in AK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of AK8. Does this perturbation cause a significant change in AK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 703,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and TAS1R1 expression is observed. Does this perturbation lead to a significant difference in TAS1R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and TAS1R1 expression is observed. Does this perturbation lead to a significant difference in TAS1R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4873,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and CAPG expression is observed. Does this perturbation lead to a significant difference in CAPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and CAPG expression is observed. Does this perturbation lead to a significant difference in CAPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3308,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ABCA13. Does this perturbation cause a significant change in ABCA13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ABCA13. Does this perturbation cause a significant change in ABCA13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2923,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 293,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and RP4-565E6.1 expression is observed. Does this perturbation lead to a significant difference in RP4-565E6.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and RP4-565E6.1 expression is observed. Does this perturbation lead to a significant difference in RP4-565E6.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and AC145110.1 expression is measured. Determine whether AC145110.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and AC145110.1 expression is measured. Determine whether AC145110.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is quantified. Does this perturbation result in a significant change in CTD-3126B10.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is quantified. Does this perturbation result in a significant change in CTD-3126B10.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of FBXL20. Does perturbing PTPN9 lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of FBXL20. Does perturbing PTPN9 lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Determine whether TEX30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Determine whether TEX30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of FEV. Does perturbing MAP4K5 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of FEV. Does perturbing MAP4K5 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6123,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLEKHO1 expression is observed. Does this perturbation lead to a significant difference in PLEKHO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLEKHO1 expression is observed. Does this perturbation lead to a significant difference in PLEKHO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of SPANXD. Does this perturbation cause a significant change in SPANXD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of SPANXD. Does this perturbation cause a significant change in SPANXD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1458,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4063,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and CCNG2 expression is observed. Does this perturbation lead to a significant difference in CCNG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and CCNG2 expression is observed. Does this perturbation lead to a significant difference in CCNG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 97,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of TDRD12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of TDRD12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 8,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5778,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RPL17-C18orf32 expression. Decide whether this perturbation leads to a significant alteration in RPL17-C18orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RPL17-C18orf32 expression. Decide whether this perturbation leads to a significant alteration in RPL17-C18orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of DPYSL2. Does perturbing SNAI1 lead to a significant change in DPYSL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of DPYSL2. Does perturbing SNAI1 lead to a significant change in DPYSL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MYOZ3 expression is measured. Determine whether MYOZ3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MYOZ3 expression is measured. Determine whether MYOZ3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of RNF182 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of RNF182 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCM2L. Does this perturbation cause a significant change in CCM2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCM2L. Does this perturbation cause a significant change in CCM2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RPL17-C18orf32. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RPL17-C18orf32. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and PLEK expression is measured. Determine whether PLEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and PLEK expression is measured. Determine whether PLEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3553,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 323,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of GPR157 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of GPR157 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-219B4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-219B4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2413,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and TEX30 expression is observed. Does this perturbation lead to a significant difference in TEX30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and TEX30 expression is observed. Does this perturbation lead to a significant difference in TEX30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of MYL4. Does perturbing ZBTB10 lead to a significant change in MYL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of MYL4. Does perturbing ZBTB10 lead to a significant change in MYL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ITGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ITGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2820,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Does this perturbation cause a significant change in RP6-159A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Does this perturbation cause a significant change in RP6-159A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in HEATR9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in HEATR9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 42,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is quantified. Does this perturbation result in a significant change in RP11-445O3.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is quantified. Does this perturbation result in a significant change in RP11-445O3.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CITED2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CITED2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Determine whether MYLIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Determine whether MYLIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3540,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Does this perturbation cause a significant change in DCAF13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Does this perturbation cause a significant change in DCAF13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of TAS2R9. Does this perturbation cause a significant change in TAS2R9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of TAS2R9. Does this perturbation cause a significant change in TAS2R9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Determine whether DYNLL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Determine whether DYNLL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SLC2A3 expression is measured. Determine whether SLC2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SLC2A3 expression is measured. Determine whether SLC2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and FAM46C expression is measured. Determine whether FAM46C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and FAM46C expression is measured. Determine whether FAM46C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in MMP19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in MMP19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of EGOT. Does perturbing PTPN13 lead to a significant change in EGOT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of EGOT. Does perturbing PTPN13 lead to a significant change in EGOT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2093,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ABCA13 expression is observed. Does this perturbation lead to a significant difference in ABCA13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ABCA13 expression is observed. Does this perturbation lead to a significant difference in ABCA13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of AFMID. Does perturbing JUN lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of AFMID. Does perturbing JUN lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LST1. Does perturbing ZBTB25 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LST1. Does perturbing ZBTB25 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and FAM19A2 expression is quantified. Does this perturbation result in a significant change in FAM19A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and FAM19A2 expression is quantified. Does this perturbation result in a significant change in FAM19A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of RP3-525N10.2. Does perturbing HOXA13 lead to a significant change in RP3-525N10.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of RP3-525N10.2. Does perturbing HOXA13 lead to a significant change in RP3-525N10.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of SLC22A13. Does this perturbation cause a significant change in SLC22A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of SLC22A13. Does this perturbation cause a significant change in SLC22A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of SLC4A3. Does this perturbation cause a significant change in SLC4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of SLC4A3. Does this perturbation cause a significant change in SLC4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 570,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Does this perturbation cause a significant change in CTC-490E21.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Does this perturbation cause a significant change in CTC-490E21.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3653,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of GRAP2. Does perturbing FOXA1 lead to a significant change in GRAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of GRAP2. Does perturbing FOXA1 lead to a significant change in GRAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of AC016629.3. Does perturbing FOXA1 lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of AC016629.3. Does perturbing FOXA1 lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2873,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP11-345P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-345P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP11-345P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-345P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in SLC38A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in SLC38A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3450,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2368,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP3-510H16.3. Does perturbing ARRDC3 lead to a significant change in RP3-510H16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP3-510H16.3. Does perturbing ARRDC3 lead to a significant change in RP3-510H16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1580,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of PHACTR1. Does this perturbation cause a significant change in PHACTR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of PHACTR1. Does this perturbation cause a significant change in PHACTR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ATP9A expression is measured. Determine whether ATP9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ATP9A expression is measured. Determine whether ATP9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2573,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-328J14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-328J14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and AKAP13 expression is quantified. Does this perturbation result in a significant change in AKAP13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and AKAP13 expression is quantified. Does this perturbation result in a significant change in AKAP13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CMB9-22P13.1. Does perturbing CDKN1B lead to a significant change in CMB9-22P13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CMB9-22P13.1. Does perturbing CDKN1B lead to a significant change in CMB9-22P13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in TUBB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in TUBB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CCDC159 expression is quantified. Does this perturbation result in a significant change in CCDC159 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CCDC159 expression is quantified. Does this perturbation result in a significant change in CCDC159 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of MFGE8. Does perturbing CITED1 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of MFGE8. Does perturbing CITED1 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ZIC4. Does perturbing PTPN12 lead to a significant change in ZIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ZIC4. Does perturbing PTPN12 lead to a significant change in ZIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Determine whether ARHGEF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Determine whether ARHGEF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5060,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Does this perturbation cause a significant change in RP11-320G24.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Does this perturbation cause a significant change in RP11-320G24.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4983,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in RP11-286H15.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in RP11-286H15.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1578,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TPP1 expression. Decide whether this perturbation leads to a significant alteration in TPP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TPP1 expression. Decide whether this perturbation leads to a significant alteration in TPP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Determine whether SLC38A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Determine whether SLC38A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of GPR157. Does this perturbation cause a significant change in GPR157 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of GPR157. Does this perturbation cause a significant change in GPR157 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of HMGA2. Does this perturbation cause a significant change in HMGA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of HMGA2. Does this perturbation cause a significant change in HMGA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Determine whether NUCB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Determine whether NUCB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of MYC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of MYC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1403,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2750,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3370,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1238,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor MYLIP expression. Decide whether this perturbation leads to a significant alteration in MYLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor MYLIP expression. Decide whether this perturbation leads to a significant alteration in MYLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RP4-550H1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RP4-550H1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is measured. Determine whether RP11-1017G21.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is measured. Determine whether RP11-1017G21.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2760,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Does this perturbation cause a significant change in IER3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Does this perturbation cause a significant change in IER3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of AGXT. Does this perturbation cause a significant change in AGXT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of AGXT. Does this perturbation cause a significant change in AGXT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and TOX expression is measured. Determine whether TOX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and TOX expression is measured. Determine whether TOX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in CHST15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in CHST15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in CPVL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in CPVL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CHI3L2. Does perturbing TBX3 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CHI3L2. Does perturbing TBX3 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SOCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SOCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3283,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and RIMBP3C expression is observed. Does this perturbation lead to a significant difference in RIMBP3C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and RIMBP3C expression is observed. Does this perturbation lead to a significant difference in RIMBP3C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 203,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and PKIG expression is observed. Does this perturbation lead to a significant difference in PKIG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and PKIG expression is observed. Does this perturbation lead to a significant difference in PKIG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 833,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and RP11-968A15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-968A15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and RP11-968A15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-968A15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3488,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of TOR3A. Does this perturbation cause a significant change in TOR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of TOR3A. Does this perturbation cause a significant change in TOR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 958,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor TRGVA expression. Decide whether this perturbation leads to a significant alteration in TRGVA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor TRGVA expression. Decide whether this perturbation leads to a significant alteration in TRGVA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TMEM55A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TMEM55A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4013,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and RP11-6D1.3 expression is observed. Does this perturbation lead to a significant difference in RP11-6D1.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and RP11-6D1.3 expression is observed. Does this perturbation lead to a significant difference in RP11-6D1.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of FCER1G. Does perturbing ISL2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of FCER1G. Does perturbing ISL2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and VASH1 expression is quantified. Does this perturbation result in a significant change in VASH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and VASH1 expression is quantified. Does this perturbation result in a significant change in VASH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and PXK expression is quantified. Does this perturbation result in a significant change in PXK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and PXK expression is quantified. Does this perturbation result in a significant change in PXK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of MYLIP. Does perturbing COL2A1 lead to a significant change in MYLIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of MYLIP. Does perturbing COL2A1 lead to a significant change in MYLIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3413,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and TPH2 expression is observed. Does this perturbation lead to a significant difference in TPH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and TPH2 expression is observed. Does this perturbation lead to a significant difference in TPH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in TMEM35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in TMEM35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of TM4SF1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of TM4SF1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is quantified. Does this perturbation result in a significant change in RP11-290L1.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is quantified. Does this perturbation result in a significant change in RP11-290L1.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 24,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLEKHO1. Does perturbing KIF18B lead to a significant change in PLEKHO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLEKHO1. Does perturbing KIF18B lead to a significant change in PLEKHO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in AIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in AIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2920,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Does this perturbation cause a significant change in ATP10D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Does this perturbation cause a significant change in ATP10D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3773,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and RP1-59D14.10 expression is observed. Does this perturbation lead to a significant difference in RP1-59D14.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and RP1-59D14.10 expression is observed. Does this perturbation lead to a significant difference in RP1-59D14.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of STRA6. Does perturbing BAK1 lead to a significant change in STRA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of STRA6. Does perturbing BAK1 lead to a significant change in STRA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of SPTAN1. Does this perturbation cause a significant change in SPTAN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of SPTAN1. Does this perturbation cause a significant change in SPTAN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is measured. Determine whether CTD-2527I21.14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is measured. Determine whether CTD-2527I21.14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Determine whether RP11-76E17.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Determine whether RP11-76E17.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2390,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 92,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and TDRD12 expression is quantified. Does this perturbation result in a significant change in TDRD12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and TDRD12 expression is quantified. Does this perturbation result in a significant change in TDRD12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2248,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ASIC4 expression. Decide whether this perturbation leads to a significant alteration in ASIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ASIC4 expression. Decide whether this perturbation leads to a significant alteration in ASIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Determine whether VGF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Determine whether VGF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Does this perturbation cause a significant change in CCNG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Does this perturbation cause a significant change in CCNG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 58,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZC3HAV1. Does perturbing CKS1B lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZC3HAV1. Does perturbing CKS1B lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 890,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Does this perturbation cause a significant change in TAS2R9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Does this perturbation cause a significant change in TAS2R9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CD52. Does perturbing EGR1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CD52. Does perturbing EGR1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 563,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ADGRF1 expression is measured. Determine whether ADGRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ADGRF1 expression is measured. Determine whether ADGRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZEB2. Does perturbing CKS1B lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZEB2. Does perturbing CKS1B lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5243,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and RP11-662J14.2 expression is observed. Does this perturbation lead to a significant difference in RP11-662J14.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and RP11-662J14.2 expression is observed. Does this perturbation lead to a significant difference in RP11-662J14.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3860,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Does this perturbation cause a significant change in DNAJB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Does this perturbation cause a significant change in DNAJB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ASIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ASIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCM2L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCM2L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1028,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TRIM31 expression is quantified. Does this perturbation result in a significant change in TRIM31 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TRIM31 expression is quantified. Does this perturbation result in a significant change in TRIM31 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1633,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and CEBPA expression is observed. Does this perturbation lead to a significant difference in CEBPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and CEBPA expression is observed. Does this perturbation lead to a significant difference in CEBPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of AMPH. Does perturbing PRDM1 lead to a significant change in AMPH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of AMPH. Does perturbing PRDM1 lead to a significant change in AMPH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM83F. Does perturbing TP73 lead to a significant change in FAM83F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM83F. Does perturbing TP73 lead to a significant change in FAM83F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ZMYND15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ZMYND15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and FAM49A expression is measured. Determine whether FAM49A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and FAM49A expression is measured. Determine whether FAM49A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of CHST15. Does perturbing TBX2 lead to a significant change in CHST15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of CHST15. Does perturbing TBX2 lead to a significant change in CHST15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of LEFTY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of LEFTY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and IER3 expression is quantified. Does this perturbation result in a significant change in IER3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and IER3 expression is quantified. Does this perturbation result in a significant change in IER3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CCNL1. Does this perturbation cause a significant change in CCNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CCNL1. Does this perturbation cause a significant change in CCNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2858,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA5 expression. Decide whether this perturbation leads to a significant alteration in ANXA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA5 expression. Decide whether this perturbation leads to a significant alteration in ANXA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 153,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and VCX3B expression is observed. Does this perturbation lead to a significant difference in VCX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and VCX3B expression is observed. Does this perturbation lead to a significant difference in VCX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1800,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1858,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor RP11-714G18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-714G18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor RP11-714G18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-714G18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is quantified. Does this perturbation result in a significant change in RP11-290K4.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is quantified. Does this perturbation result in a significant change in RP11-290K4.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and PXK expression is measured. Determine whether PXK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and PXK expression is measured. Determine whether PXK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of PTPRS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of PTPRS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of DDX58. Does this perturbation cause a significant change in DDX58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of DDX58. Does this perturbation cause a significant change in DDX58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5593,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01395 expression is observed. Does this perturbation lead to a significant difference in LINC01395 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01395 expression is observed. Does this perturbation lead to a significant difference in LINC01395 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ZIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ZIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and SLC38A2 expression is quantified. Does this perturbation result in a significant change in SLC38A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and SLC38A2 expression is quantified. Does this perturbation result in a significant change in SLC38A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 338,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor LRRC36 expression. Decide whether this perturbation leads to a significant alteration in LRRC36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor LRRC36 expression. Decide whether this perturbation leads to a significant alteration in LRRC36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in RP1-59D14.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in RP1-59D14.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1660,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Does this perturbation cause a significant change in ABCB11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Does this perturbation cause a significant change in ABCB11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1973,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and POC1B-GALNT4 expression is observed. Does this perturbation lead to a significant difference in POC1B-GALNT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and POC1B-GALNT4 expression is observed. Does this perturbation lead to a significant difference in POC1B-GALNT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PCDHGA6. Does perturbing ZBTB25 lead to a significant change in PCDHGA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PCDHGA6. Does perturbing ZBTB25 lead to a significant change in PCDHGA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CTD-2527I21.14. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CTD-2527I21.14. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2463,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C6orf1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C6orf1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and TACC1 expression is measured. Determine whether TACC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and TACC1 expression is measured. Determine whether TACC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4753,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of SIGLEC15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of SIGLEC15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3353,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and VASH1 expression is observed. Does this perturbation lead to a significant difference in VASH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and VASH1 expression is observed. Does this perturbation lead to a significant difference in VASH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2958,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SLC20A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SLC20A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and VGF expression is quantified. Does this perturbation result in a significant change in VGF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and VGF expression is quantified. Does this perturbation result in a significant change in VGF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in PKIG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in PKIG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in UCKL1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in UCKL1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of YPEL3. Does this perturbation cause a significant change in YPEL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of YPEL3. Does this perturbation cause a significant change in YPEL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 380,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Does this perturbation cause a significant change in CPXM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Does this perturbation cause a significant change in CPXM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is quantified. Does this perturbation result in a significant change in RP11-355B11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is quantified. Does this perturbation result in a significant change in RP11-355B11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1640,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of MYB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of MYB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of BTG2. Does perturbing POU3F2 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of BTG2. Does perturbing POU3F2 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C8orf22 expression is quantified. Does this perturbation result in a significant change in C8orf22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C8orf22 expression is quantified. Does this perturbation result in a significant change in C8orf22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4083,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RP5-1142A6.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RP5-1142A6.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 633,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and COL18A1-AS1 expression is observed. Does this perturbation lead to a significant difference in COL18A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and COL18A1-AS1 expression is observed. Does this perturbation lead to a significant difference in COL18A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Determine whether RP11-91A18.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Determine whether RP11-91A18.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1663,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ABCB11 expression is observed. Does this perturbation lead to a significant difference in ABCB11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ABCB11 expression is observed. Does this perturbation lead to a significant difference in ABCB11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01395. Does perturbing ZBTB10 lead to a significant change in LINC01395 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01395. Does perturbing ZBTB10 lead to a significant change in LINC01395 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5788,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor INHBE expression. Decide whether this perturbation leads to a significant alteration in INHBE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor INHBE expression. Decide whether this perturbation leads to a significant alteration in INHBE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Determine whether MSX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Determine whether MSX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of AC074289.1. Does perturbing DLX2 lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of AC074289.1. Does perturbing DLX2 lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of KRTAP9-9. Does perturbing ATL1 lead to a significant change in KRTAP9-9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of KRTAP9-9. Does perturbing ATL1 lead to a significant change in KRTAP9-9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5368,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor CTSW expression. Decide whether this perturbation leads to a significant alteration in CTSW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor CTSW expression. Decide whether this perturbation leads to a significant alteration in CTSW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5460,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Does this perturbation cause a significant change in CHP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Does this perturbation cause a significant change in CHP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of IGHEP2. Does perturbing ZBTB1 lead to a significant change in IGHEP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of IGHEP2. Does perturbing ZBTB1 lead to a significant change in IGHEP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CKS2. Does perturbing POU3F2 lead to a significant change in CKS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CKS2. Does perturbing POU3F2 lead to a significant change in CKS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5240,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Does this perturbation cause a significant change in RP11-662J14.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Does this perturbation cause a significant change in RP11-662J14.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5328,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ATF6B expression. Decide whether this perturbation leads to a significant alteration in ATF6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ATF6B expression. Decide whether this perturbation leads to a significant alteration in ATF6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RGPD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RGPD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 27,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and AKAP13 expression is measured. Determine whether AKAP13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and AKAP13 expression is measured. Determine whether AKAP13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4238,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FCER1G. Does perturbing PTPN13 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FCER1G. Does perturbing PTPN13 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FAM101B. Does perturbing FOXA1 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FAM101B. Does perturbing FOXA1 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of FABP5. Does perturbing POU3F2 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of FABP5. Does perturbing POU3F2 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ESAM. Does perturbing KIAA1804 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ESAM. Does perturbing KIAA1804 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 658,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor STRA6 expression. Decide whether this perturbation leads to a significant alteration in STRA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor STRA6 expression. Decide whether this perturbation leads to a significant alteration in STRA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of FAM46C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of FAM46C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Determine whether PRKAG2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Determine whether PRKAG2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 49,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is measured. Determine whether RP11-445O3.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is measured. Determine whether RP11-445O3.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and FILIP1L expression is quantified. Does this perturbation result in a significant change in FILIP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and FILIP1L expression is quantified. Does this perturbation result in a significant change in FILIP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4890,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Does this perturbation cause a significant change in SLC7A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Does this perturbation cause a significant change in SLC7A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of RABAC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of RABAC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in IER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in IER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of NCALD. Does perturbing UBASH3A lead to a significant change in NCALD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of NCALD. Does perturbing UBASH3A lead to a significant change in NCALD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4580,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Does this perturbation cause a significant change in FNDC3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Does this perturbation cause a significant change in FNDC3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4330,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Does this perturbation cause a significant change in CCNB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Does this perturbation cause a significant change in CCNB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and EMP3 expression is measured. Determine whether EMP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and EMP3 expression is measured. Determine whether EMP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 333,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and LRRC36 expression is observed. Does this perturbation lead to a significant difference in LRRC36 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and LRRC36 expression is observed. Does this perturbation lead to a significant difference in LRRC36 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of HMOX1. Does perturbing CITED1 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of HMOX1. Does perturbing CITED1 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CARMN. Does this perturbation cause a significant change in CARMN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CARMN. Does this perturbation cause a significant change in CARMN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ARHGEF6. Does this perturbation cause a significant change in ARHGEF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ARHGEF6. Does this perturbation cause a significant change in ARHGEF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Determine whether ANXA2R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Determine whether ANXA2R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4090,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and NUCB2 expression is quantified. Does this perturbation result in a significant change in NUCB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and NUCB2 expression is quantified. Does this perturbation result in a significant change in NUCB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2388,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor HEATR9 expression. Decide whether this perturbation leads to a significant alteration in HEATR9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor HEATR9 expression. Decide whether this perturbation leads to a significant alteration in HEATR9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3428,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor APOL6 expression. Decide whether this perturbation leads to a significant alteration in APOL6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor APOL6 expression. Decide whether this perturbation leads to a significant alteration in APOL6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and PCDHGA3 expression is measured. Determine whether PCDHGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and PCDHGA3 expression is measured. Determine whether PCDHGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of GCM2. Does perturbing MAP4K5 lead to a significant change in GCM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of GCM2. Does perturbing MAP4K5 lead to a significant change in GCM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in RP3-525N10.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in RP3-525N10.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3918,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of S100A4. Does perturbing SLC4A1 lead to a significant change in S100A4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of S100A4. Does perturbing SLC4A1 lead to a significant change in S100A4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in PGA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in PGA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Determine whether RP11-345P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Determine whether RP11-345P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ITGA3 expression is measured. Determine whether ITGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ITGA3 expression is measured. Determine whether ITGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in RP11-6D1.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in RP11-6D1.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of C1orf228 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of C1orf228 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MBP. Does this perturbation cause a significant change in MBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MBP. Does this perturbation cause a significant change in MBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 980,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Does this perturbation cause a significant change in MS4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Does this perturbation cause a significant change in MS4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of SOCS1. Does perturbing UBASH3B lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of SOCS1. Does perturbing UBASH3B lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and LEFTY2 expression is quantified. Does this perturbation result in a significant change in LEFTY2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and LEFTY2 expression is quantified. Does this perturbation result in a significant change in LEFTY2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4990,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Does this perturbation cause a significant change in MARCKS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Does this perturbation cause a significant change in MARCKS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ADGRF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ADGRF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ACTC1 expression is quantified. Does this perturbation result in a significant change in ACTC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ACTC1 expression is quantified. Does this perturbation result in a significant change in ACTC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6053,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in TMEM154 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in TMEM154 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CCRL2. Does perturbing FOXA1 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CCRL2. Does perturbing FOXA1 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2238,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor TAPBP expression. Decide whether this perturbation leads to a significant alteration in TAPBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor TAPBP expression. Decide whether this perturbation leads to a significant alteration in TAPBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 830,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Does this perturbation cause a significant change in RP11-968A15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Does this perturbation cause a significant change in RP11-968A15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is measured. Determine whether RP11-345P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is measured. Determine whether RP11-345P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is quantified. Does this perturbation result in a significant change in RP11-514P8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is quantified. Does this perturbation result in a significant change in RP11-514P8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5070,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Does this perturbation cause a significant change in LINC01338 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Does this perturbation cause a significant change in LINC01338 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 920,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and N4BP2L2 expression is measured. Determine whether N4BP2L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and N4BP2L2 expression is measured. Determine whether N4BP2L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Determine whether TNFAIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Determine whether TNFAIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1618,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of TNFAIP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of TNFAIP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 26,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of MKNK2. Does this perturbation cause a significant change in MKNK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of MKNK2. Does this perturbation cause a significant change in MKNK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of BST2. Does perturbing RUNX1T1 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of BST2. Does perturbing RUNX1T1 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of AREG. Does this perturbation cause a significant change in AREG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of AREG. Does this perturbation cause a significant change in AREG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RIT1. Does perturbing NCL lead to a significant change in RIT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RIT1. Does perturbing NCL lead to a significant change in RIT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3448,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor KCNH2 expression. Decide whether this perturbation leads to a significant alteration in KCNH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor KCNH2 expression. Decide whether this perturbation leads to a significant alteration in KCNH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 778,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RNF168 expression. Decide whether this perturbation leads to a significant alteration in RNF168 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RNF168 expression. Decide whether this perturbation leads to a significant alteration in RNF168 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4073,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and RP11-452C8.1 expression is observed. Does this perturbation lead to a significant difference in RP11-452C8.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and RP11-452C8.1 expression is observed. Does this perturbation lead to a significant difference in RP11-452C8.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is measured. Determine whether RP11-320G24.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is measured. Determine whether RP11-320G24.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of AIF1. Does perturbing HK2 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of AIF1. Does perturbing HK2 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Determine whether CSRNP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Determine whether CSRNP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of RELB. Does perturbing PTPN13 lead to a significant change in RELB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of RELB. Does perturbing PTPN13 lead to a significant change in RELB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Determine whether AC004051.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Determine whether AC004051.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in NCALD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in NCALD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PIM2. Does perturbing PTPN9 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PIM2. Does perturbing PTPN9 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2020,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Does this perturbation cause a significant change in CTSS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Does this perturbation cause a significant change in CTSS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLA2G16. Does this perturbation cause a significant change in PLA2G16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLA2G16. Does this perturbation cause a significant change in PLA2G16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1830,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Does this perturbation cause a significant change in SLC22A25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Does this perturbation cause a significant change in SLC22A25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of RP11-286H15.1. Does this perturbation cause a significant change in RP11-286H15.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of RP11-286H15.1. Does this perturbation cause a significant change in RP11-286H15.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Determine whether RP11-38J22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Determine whether RP11-38J22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5310,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Does this perturbation cause a significant change in EWSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Does this perturbation cause a significant change in EWSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and IL20 expression is measured. Determine whether IL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and IL20 expression is measured. Determine whether IL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is quantified. Does this perturbation result in a significant change in RP11-452C8.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is quantified. Does this perturbation result in a significant change in RP11-452C8.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in RNF182 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in RNF182 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3118,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor AC145110.1 expression. Decide whether this perturbation leads to a significant alteration in AC145110.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor AC145110.1 expression. Decide whether this perturbation leads to a significant alteration in AC145110.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1638,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor CEBPA expression. Decide whether this perturbation leads to a significant alteration in CEBPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor CEBPA expression. Decide whether this perturbation leads to a significant alteration in CEBPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and DLX4 expression is measured. Determine whether DLX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and DLX4 expression is measured. Determine whether DLX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01420 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01420 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5438,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01227 expression. Decide whether this perturbation leads to a significant alteration in LINC01227 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01227 expression. Decide whether this perturbation leads to a significant alteration in LINC01227 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and LEFTY2 expression is measured. Determine whether LEFTY2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and LEFTY2 expression is measured. Determine whether LEFTY2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CIB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CIB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in LINC01338 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in LINC01338 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and CBL expression is measured. Determine whether CBL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and CBL expression is measured. Determine whether CBL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 740,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3678,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MS4A2. Does this perturbation cause a significant change in MS4A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MS4A2. Does this perturbation cause a significant change in MS4A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of POC1B-GALNT4. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of POC1B-GALNT4. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Determine whether LRP10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Determine whether LRP10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CYP2C18. Does this perturbation cause a significant change in CYP2C18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CYP2C18. Does this perturbation cause a significant change in CYP2C18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4338,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor CCNB2 expression. Decide whether this perturbation leads to a significant alteration in CCNB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor CCNB2 expression. Decide whether this perturbation leads to a significant alteration in CCNB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of PYROXD2. Does perturbing STIL lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of PYROXD2. Does perturbing STIL lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5283,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3218,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of RP11-662J14.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of RP11-662J14.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Determine whether ABCA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Determine whether ABCA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Determine whether CPXM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Determine whether CPXM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of HOXB6. Does this perturbation cause a significant change in HOXB6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of HOXB6. Does this perturbation cause a significant change in HOXB6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of PHGDH. Does perturbing TMSB4X lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of PHGDH. Does perturbing TMSB4X lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MYOZ3. Does this perturbation cause a significant change in MYOZ3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MYOZ3. Does this perturbation cause a significant change in MYOZ3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4938,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor CPVL expression. Decide whether this perturbation leads to a significant alteration in CPVL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor CPVL expression. Decide whether this perturbation leads to a significant alteration in CPVL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of HOXB6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of HOXB6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of PRKAG2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of PRKAG2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Determine whether RIMBP3C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Determine whether RIMBP3C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 50,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3138,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor NUCB2 expression. Decide whether this perturbation leads to a significant alteration in NUCB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor NUCB2 expression. Decide whether this perturbation leads to a significant alteration in NUCB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and HIST1H3H expression is quantified. Does this perturbation result in a significant change in HIST1H3H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and HIST1H3H expression is quantified. Does this perturbation result in a significant change in HIST1H3H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in MME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in MME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of TTC9B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of TTC9B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of FMNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of FMNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is quantified. Does this perturbation result in a significant change in CTD-2012K14.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is quantified. Does this perturbation result in a significant change in CTD-2012K14.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and RSPO4 expression is measured. Determine whether RSPO4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and RSPO4 expression is measured. Determine whether RSPO4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in CNN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in CNN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in RP11-91A18.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in RP11-91A18.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1723,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CTD-2031P19.5. Does perturbing SET lead to a significant change in CTD-2031P19.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CTD-2031P19.5. Does perturbing SET lead to a significant change in CTD-2031P19.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in RLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in RLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and MT1E expression is measured. Determine whether MT1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and MT1E expression is measured. Determine whether MT1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4248,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor SEMA3B expression. Decide whether this perturbation leads to a significant alteration in SEMA3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor SEMA3B expression. Decide whether this perturbation leads to a significant alteration in SEMA3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 610,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1128,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTC-492K19.4 expression. Decide whether this perturbation leads to a significant alteration in CTC-492K19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTC-492K19.4 expression. Decide whether this perturbation leads to a significant alteration in CTC-492K19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 793,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of RP1-59D14.10. Does perturbing BPGM lead to a significant change in RP1-59D14.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of RP1-59D14.10. Does perturbing BPGM lead to a significant change in RP1-59D14.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CIB3 expression is measured. Determine whether CIB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CIB3 expression is measured. Determine whether CIB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of FBXL20. Does perturbing IER5L lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of FBXL20. Does perturbing IER5L lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5993,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of DEK. Does perturbing CBFA2T3 lead to a significant change in DEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of DEK. Does perturbing CBFA2T3 lead to a significant change in DEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5633,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and DPYSL2 expression is measured. Determine whether DPYSL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and DPYSL2 expression is measured. Determine whether DPYSL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5108,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Determine whether CNN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Determine whether CNN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4050,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Does this perturbation cause a significant change in PROX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Does this perturbation cause a significant change in PROX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TRIM31 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TRIM31 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CTD-2527I21.14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CTD-2527I21.14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of CTSS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of CTSS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3240,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Does this perturbation cause a significant change in CD37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Does this perturbation cause a significant change in CD37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TRIM31. Does this perturbation cause a significant change in TRIM31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TRIM31. Does this perturbation cause a significant change in TRIM31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of C1orf141 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of C1orf141 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5928,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA2. Does this perturbation cause a significant change in ANXA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA2. Does this perturbation cause a significant change in ANXA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3350,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Does this perturbation cause a significant change in VASH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Does this perturbation cause a significant change in VASH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2440,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Does this perturbation cause a significant change in AC064834.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Does this perturbation cause a significant change in AC064834.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Determine whether SPANXN5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Determine whether SPANXN5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of FAM225B. Does perturbing CEBPB lead to a significant change in FAM225B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of FAM225B. Does perturbing CEBPB lead to a significant change in FAM225B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 74,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1790,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Does this perturbation cause a significant change in RP11-128B16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Does this perturbation cause a significant change in RP11-128B16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of SOX4. Does perturbing CDKN1A lead to a significant change in SOX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of SOX4. Does perturbing CDKN1A lead to a significant change in SOX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of AKAP13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of AKAP13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of INHBE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of INHBE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2713,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TUBA1A expression is observed. Does this perturbation lead to a significant difference in TUBA1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TUBA1A expression is observed. Does this perturbation lead to a significant difference in TUBA1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3670,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 86,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2588,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of LINC00479. Does this perturbation cause a significant change in LINC00479 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of LINC00479. Does this perturbation cause a significant change in LINC00479 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3723,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and FABP3 expression is observed. Does this perturbation lead to a significant difference in FABP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and FABP3 expression is observed. Does this perturbation lead to a significant difference in FABP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of CTC-490E21.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of CTC-490E21.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5718,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor RHOXF2BB expression. Decide whether this perturbation leads to a significant alteration in RHOXF2BB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor RHOXF2BB expression. Decide whether this perturbation leads to a significant alteration in RHOXF2BB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 213,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5198,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor HCAR2 expression. Decide whether this perturbation leads to a significant alteration in HCAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor HCAR2 expression. Decide whether this perturbation leads to a significant alteration in HCAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of AKAP13. Does perturbing MAP2K6 lead to a significant change in AKAP13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of AKAP13. Does perturbing MAP2K6 lead to a significant change in AKAP13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CHP1. Does this perturbation cause a significant change in CHP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CHP1. Does this perturbation cause a significant change in CHP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2680,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Does this perturbation cause a significant change in FAM83F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Does this perturbation cause a significant change in FAM83F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4473,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of RELB. Does this perturbation cause a significant change in RELB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of RELB. Does this perturbation cause a significant change in RELB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6258,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor TRAPPC3L expression. Decide whether this perturbation leads to a significant alteration in TRAPPC3L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor TRAPPC3L expression. Decide whether this perturbation leads to a significant alteration in TRAPPC3L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of KRTAP9-9. Does this perturbation cause a significant change in KRTAP9-9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of KRTAP9-9. Does this perturbation cause a significant change in KRTAP9-9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4638,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of CTSS. Does perturbing S1PR2 lead to a significant change in CTSS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of CTSS. Does perturbing S1PR2 lead to a significant change in CTSS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5868,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor VMP1 expression. Decide whether this perturbation leads to a significant alteration in VMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor VMP1 expression. Decide whether this perturbation leads to a significant alteration in VMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4020,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and SH3BGRL expression is quantified. Does this perturbation result in a significant change in SH3BGRL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and SH3BGRL expression is quantified. Does this perturbation result in a significant change in SH3BGRL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ZMYND15. Does perturbing MAP7D1 lead to a significant change in ZMYND15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ZMYND15. Does perturbing MAP7D1 lead to a significant change in ZMYND15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2883,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PSMB9 expression is quantified. Does this perturbation result in a significant change in PSMB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PSMB9 expression is quantified. Does this perturbation result in a significant change in PSMB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of AC078941.1. Does perturbing S1PR2 lead to a significant change in AC078941.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of AC078941.1. Does perturbing S1PR2 lead to a significant change in AC078941.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ANXA3. Does this perturbation cause a significant change in ANXA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ANXA3. Does this perturbation cause a significant change in ANXA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Determine whether PCDHGA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Determine whether PCDHGA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is measured. Determine whether TFAP2A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is measured. Determine whether TFAP2A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5300,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Does this perturbation cause a significant change in PPFIA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Does this perturbation cause a significant change in PPFIA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3420,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Does this perturbation cause a significant change in APOL6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Does this perturbation cause a significant change in APOL6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Determine whether LINC01562 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Determine whether LINC01562 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3473,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and AC139099.6 expression is observed. Does this perturbation lead to a significant difference in AC139099.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and AC139099.6 expression is observed. Does this perturbation lead to a significant difference in AC139099.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ORAI3. Does perturbing RUNX1T1 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ORAI3. Does perturbing RUNX1T1 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and RP11-195C7.1 expression is measured. Determine whether RP11-195C7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and RP11-195C7.1 expression is measured. Determine whether RP11-195C7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4213,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Determine whether ETS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Determine whether ETS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLEKHO1. Does this perturbation cause a significant change in PLEKHO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLEKHO1. Does this perturbation cause a significant change in PLEKHO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of KRT79. Does this perturbation cause a significant change in KRT79 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of KRT79. Does this perturbation cause a significant change in KRT79 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2233,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and TAPBP expression is observed. Does this perturbation lead to a significant difference in TAPBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and TAPBP expression is observed. Does this perturbation lead to a significant difference in TAPBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MBP. Does perturbing LHX1 lead to a significant change in MBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MBP. Does perturbing LHX1 lead to a significant change in MBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3253,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and UNC5B expression is observed. Does this perturbation lead to a significant difference in UNC5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and UNC5B expression is observed. Does this perturbation lead to a significant difference in UNC5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1190,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and KRT79 expression is measured. Determine whether KRT79 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and KRT79 expression is measured. Determine whether KRT79 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 628,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2450,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Does this perturbation cause a significant change in RETN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Does this perturbation cause a significant change in RETN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of SH3BGRL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of SH3BGRL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5603,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and FCGR3A expression is observed. Does this perturbation lead to a significant difference in FCGR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and FCGR3A expression is observed. Does this perturbation lead to a significant difference in FCGR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5618,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01358 expression. Decide whether this perturbation leads to a significant alteration in LINC01358 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01358 expression. Decide whether this perturbation leads to a significant alteration in LINC01358 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2638,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor AC007193.6 expression. Decide whether this perturbation leads to a significant alteration in AC007193.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor AC007193.6 expression. Decide whether this perturbation leads to a significant alteration in AC007193.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2063,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and PGA4 expression is measured. Determine whether PGA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and PGA4 expression is measured. Determine whether PGA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Determine whether DPYSL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Determine whether DPYSL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ARMCX3 expression is quantified. Does this perturbation result in a significant change in ARMCX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ARMCX3 expression is quantified. Does this perturbation result in a significant change in ARMCX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2780,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and SLC22A13 expression is quantified. Does this perturbation result in a significant change in SLC22A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and SLC22A13 expression is quantified. Does this perturbation result in a significant change in SLC22A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 220,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Does this perturbation cause a significant change in DDX58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Does this perturbation cause a significant change in DDX58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2420,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Does this perturbation cause a significant change in SDSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Does this perturbation cause a significant change in SDSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ORAI3 expression is quantified. Does this perturbation result in a significant change in ORAI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ORAI3 expression is quantified. Does this perturbation result in a significant change in ORAI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3738,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Determine whether CTD-3126B10.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Determine whether CTD-3126B10.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FAM83A. Does perturbing PTPN13 lead to a significant change in FAM83A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FAM83A. Does perturbing PTPN13 lead to a significant change in FAM83A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3840,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in AC145110.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in AC145110.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of LBH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of LBH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4950,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in STRA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in STRA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1150,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of NPW. Does this perturbation cause a significant change in NPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of NPW. Does this perturbation cause a significant change in NPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Determine whether DYNLT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Determine whether DYNLT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Determine whether SLCO6A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Determine whether SLCO6A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4900,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Does this perturbation cause a significant change in RP11-285F7.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Does this perturbation cause a significant change in RP11-285F7.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ACP5. Does perturbing COL2A1 lead to a significant change in ACP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ACP5. Does perturbing COL2A1 lead to a significant change in ACP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MBP expression is measured. Determine whether MBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MBP expression is measured. Determine whether MBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1428,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor TRPM2 expression. Decide whether this perturbation leads to a significant alteration in TRPM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor TRPM2 expression. Decide whether this perturbation leads to a significant alteration in TRPM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RUNX3 expression is quantified. Does this perturbation result in a significant change in RUNX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RUNX3 expression is quantified. Does this perturbation result in a significant change in RUNX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3843,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1193,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and CTD-2616J11.16 expression is observed. Does this perturbation lead to a significant difference in CTD-2616J11.16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and CTD-2616J11.16 expression is observed. Does this perturbation lead to a significant difference in CTD-2616J11.16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of TFAP2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of TFAP2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in HSD17B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in HSD17B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of POC1B-GALNT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of POC1B-GALNT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and COL21A1 expression is measured. Determine whether COL21A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and COL21A1 expression is measured. Determine whether COL21A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 568,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of SLC38A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of SLC38A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 44,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP11-445O3.3. Does this perturbation cause a significant change in RP11-445O3.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP11-445O3.3. Does this perturbation cause a significant change in RP11-445O3.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1703,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and SP6 expression is observed. Does this perturbation lead to a significant difference in SP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and SP6 expression is observed. Does this perturbation lead to a significant difference in SP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1953,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of PSMB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of PSMB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Determine whether RP11-180M15.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Determine whether RP11-180M15.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Determine whether HBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Determine whether HBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 37,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of PDE1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of PDE1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of RP1-102K2.6. Does perturbing IRF1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of RP1-102K2.6. Does perturbing IRF1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is measured. Determine whether RP11-202A13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is measured. Determine whether RP11-202A13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3050,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Does this perturbation cause a significant change in GPR157 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Does this perturbation cause a significant change in GPR157 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in RP11-445F12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in RP11-445F12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ANXA2R expression is measured. Determine whether ANXA2R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ANXA2R expression is measured. Determine whether ANXA2R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA5. Does this perturbation cause a significant change in ANXA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA5. Does this perturbation cause a significant change in ANXA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and LINC00479 expression is quantified. Does this perturbation result in a significant change in LINC00479 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and LINC00479 expression is quantified. Does this perturbation result in a significant change in LINC00479 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Determine whether RPS6KA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Determine whether RPS6KA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and FILIP1L expression is measured. Determine whether FILIP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and FILIP1L expression is measured. Determine whether FILIP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of RP11-290L1.2. Does perturbing S1PR2 lead to a significant change in RP11-290L1.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of RP11-290L1.2. Does perturbing S1PR2 lead to a significant change in RP11-290L1.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ACTB. Does perturbing POU3F2 lead to a significant change in ACTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ACTB. Does perturbing POU3F2 lead to a significant change in ACTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of RP11-6D1.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of RP11-6D1.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of NUCB2. Does perturbing HOXC13 lead to a significant change in NUCB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of NUCB2. Does perturbing HOXC13 lead to a significant change in NUCB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3570,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3660,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01227 expression is quantified. Does this perturbation result in a significant change in LINC01227 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01227 expression is quantified. Does this perturbation result in a significant change in LINC01227 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5033,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and CCDC136 expression is observed. Does this perturbation lead to a significant difference in CCDC136 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and CCDC136 expression is observed. Does this perturbation lead to a significant difference in CCDC136 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ANTXR2 expression is quantified. Does this perturbation result in a significant change in ANTXR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ANTXR2 expression is quantified. Does this perturbation result in a significant change in ANTXR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Determine whether LRRC74B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Determine whether LRRC74B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-128B16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-128B16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and HEATR9 expression is quantified. Does this perturbation result in a significant change in HEATR9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and HEATR9 expression is quantified. Does this perturbation result in a significant change in HEATR9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and RP1-59D14.10 expression is quantified. Does this perturbation result in a significant change in RP1-59D14.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and RP1-59D14.10 expression is quantified. Does this perturbation result in a significant change in RP1-59D14.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 643,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and CTA-384D8.34 expression is observed. Does this perturbation lead to a significant difference in CTA-384D8.34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and CTA-384D8.34 expression is observed. Does this perturbation lead to a significant difference in CTA-384D8.34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of RETN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of RETN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is measured. Determine whether RP11-83A24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is measured. Determine whether RP11-83A24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ARMCX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ARMCX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4263,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and AC064834.2 expression is quantified. Does this perturbation result in a significant change in AC064834.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and AC064834.2 expression is quantified. Does this perturbation result in a significant change in AC064834.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5498,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor IGFL2 expression. Decide whether this perturbation leads to a significant alteration in IGFL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor IGFL2 expression. Decide whether this perturbation leads to a significant alteration in IGFL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1768,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ST3GAL5 expression. Decide whether this perturbation leads to a significant alteration in ST3GAL5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ST3GAL5 expression. Decide whether this perturbation leads to a significant alteration in ST3GAL5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3680,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of RP11-6D1.3. Does this perturbation cause a significant change in RP11-6D1.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of RP11-6D1.3. Does this perturbation cause a significant change in RP11-6D1.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and NPW expression is measured. Determine whether NPW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and NPW expression is measured. Determine whether NPW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2010,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Does this perturbation cause a significant change in AC078941.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Does this perturbation cause a significant change in AC078941.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of CBL. Does perturbing HOXC13 lead to a significant change in CBL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of CBL. Does perturbing HOXC13 lead to a significant change in CBL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3348,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor RP11-76E17.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-76E17.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor RP11-76E17.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-76E17.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM83F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM83F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2303,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6030,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Does this perturbation cause a significant change in PGA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Does this perturbation cause a significant change in PGA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3900,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Does this perturbation cause a significant change in TNFRSF12A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Does this perturbation cause a significant change in TNFRSF12A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of DRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of DRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 18,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor CLU expression. Decide whether this perturbation leads to a significant alteration in CLU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor CLU expression. Decide whether this perturbation leads to a significant alteration in CLU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Does this perturbation cause a significant change in CENPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Does this perturbation cause a significant change in CENPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of C17orf64. Does perturbing HES7 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of C17orf64. Does perturbing HES7 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5938,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of INADL. Does this perturbation cause a significant change in INADL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of INADL. Does this perturbation cause a significant change in INADL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4548,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Determine whether SOX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Determine whether SOX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3128,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor AIM1 expression. Decide whether this perturbation leads to a significant alteration in AIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor AIM1 expression. Decide whether this perturbation leads to a significant alteration in AIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5888,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RGPD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RGPD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ST3GAL5. Does this perturbation cause a significant change in ST3GAL5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ST3GAL5. Does this perturbation cause a significant change in ST3GAL5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 748,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4850,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is quantified. Does this perturbation result in a significant change in XX-FW83563B9.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is quantified. Does this perturbation result in a significant change in XX-FW83563B9.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 89,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of AC007556.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of AC007556.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of STRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of STRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of IGHEP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of IGHEP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4468,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MYOZ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MYOZ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM118A expression is quantified. Does this perturbation result in a significant change in FAM118A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM118A expression is quantified. Does this perturbation result in a significant change in FAM118A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and TTC9B expression is quantified. Does this perturbation result in a significant change in TTC9B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and TTC9B expression is quantified. Does this perturbation result in a significant change in TTC9B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and HOGA1 expression is quantified. Does this perturbation result in a significant change in HOGA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and HOGA1 expression is quantified. Does this perturbation result in a significant change in HOGA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-646I6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-646I6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of FILIP1L. Does this perturbation cause a significant change in FILIP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of FILIP1L. Does this perturbation cause a significant change in FILIP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1490,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Does this perturbation cause a significant change in MAOB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Does this perturbation cause a significant change in MAOB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in TRPM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in TRPM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of UNC5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of UNC5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ARMCX3. Does perturbing MAP2K6 lead to a significant change in ARMCX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ARMCX3. Does perturbing MAP2K6 lead to a significant change in ARMCX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3700,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Does this perturbation cause a significant change in RP11-290K4.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Does this perturbation cause a significant change in RP11-290K4.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 243,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4043,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-109E24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-109E24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CTD-2031P19.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CTD-2031P19.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CCNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CCNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2508,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor AREG expression. Decide whether this perturbation leads to a significant alteration in AREG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor AREG expression. Decide whether this perturbation leads to a significant alteration in AREG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Determine whether HMGA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Determine whether HMGA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01358 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01358 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of GPR35. Does perturbing LYL1 lead to a significant change in GPR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of GPR35. Does perturbing LYL1 lead to a significant change in GPR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Determine whether LINC01227 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Determine whether LINC01227 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of FABP5. Does perturbing KMT2A lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of FABP5. Does perturbing KMT2A lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of FNDC3A. Does perturbing KIF2C lead to a significant change in FNDC3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of FNDC3A. Does perturbing KIF2C lead to a significant change in FNDC3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 65,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 620,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is measured. Determine whether CMB9-22P13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is measured. Determine whether CMB9-22P13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in DDX58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in DDX58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2603,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 230,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Does this perturbation cause a significant change in ARRDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Does this perturbation cause a significant change in ARRDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Determine whether ADGRF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Determine whether ADGRF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2318,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor TFAP2A expression. Decide whether this perturbation leads to a significant alteration in TFAP2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor TFAP2A expression. Decide whether this perturbation leads to a significant alteration in TFAP2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1500,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Does this perturbation cause a significant change in BMP2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Does this perturbation cause a significant change in BMP2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4920,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Does this perturbation cause a significant change in BCL2L11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Does this perturbation cause a significant change in BCL2L11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and TAPBP expression is quantified. Does this perturbation result in a significant change in TAPBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and TAPBP expression is quantified. Does this perturbation result in a significant change in TAPBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is measured. Determine whether RP11-290K4.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is measured. Determine whether RP11-290K4.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Determine whether MSRB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Determine whether MSRB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4413,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CTD-2527I21.14 expression is observed. Does this perturbation lead to a significant difference in CTD-2527I21.14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CTD-2527I21.14 expression is observed. Does this perturbation lead to a significant difference in CTD-2527I21.14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is measured. Determine whether CTC-490E21.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is measured. Determine whether CTC-490E21.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and HBG1 expression is measured. Determine whether HBG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and HBG1 expression is measured. Determine whether HBG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in COL18A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in COL18A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of AC004051.2. Does perturbing FOXO4 lead to a significant change in AC004051.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of AC004051.2. Does perturbing FOXO4 lead to a significant change in AC004051.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RP5-1142A6.2. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RP5-1142A6.2. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6263,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and MME expression is observed. Does this perturbation lead to a significant difference in MME expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and MME expression is observed. Does this perturbation lead to a significant difference in MME expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5598,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01395 expression. Decide whether this perturbation leads to a significant alteration in LINC01395 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01395 expression. Decide whether this perturbation leads to a significant alteration in LINC01395 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD47 expression is quantified. Does this perturbation result in a significant change in CD47 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD47 expression is quantified. Does this perturbation result in a significant change in CD47 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of TAPBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of TAPBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3378,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5530,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Does this perturbation cause a significant change in MOGAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Does this perturbation cause a significant change in MOGAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is quantified. Does this perturbation result in a significant change in RPL17-C18orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is quantified. Does this perturbation result in a significant change in RPL17-C18orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SLC22A25 expression is quantified. Does this perturbation result in a significant change in SLC22A25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SLC22A25 expression is quantified. Does this perturbation result in a significant change in SLC22A25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of H1FNT. Does perturbing C19orf26 lead to a significant change in H1FNT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of H1FNT. Does perturbing C19orf26 lead to a significant change in H1FNT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5910,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Does this perturbation cause a significant change in LEFTY1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Does this perturbation cause a significant change in LEFTY1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3180,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and RP11-195C7.1 expression is quantified. Does this perturbation result in a significant change in RP11-195C7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and RP11-195C7.1 expression is quantified. Does this perturbation result in a significant change in RP11-195C7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and SLC31A2 expression is quantified. Does this perturbation result in a significant change in SLC31A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and SLC31A2 expression is quantified. Does this perturbation result in a significant change in SLC31A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is quantified. Does this perturbation result in a significant change in RHOXF2BB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is quantified. Does this perturbation result in a significant change in RHOXF2BB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-290K4.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-290K4.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4380,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Does this perturbation cause a significant change in PHACTR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Does this perturbation cause a significant change in PHACTR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2078,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CKS2 expression. Decide whether this perturbation leads to a significant alteration in CKS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CKS2 expression. Decide whether this perturbation leads to a significant alteration in CKS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CTD-3131K8.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CTD-3131K8.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Determine whether CTSS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Determine whether CTSS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of HEATR9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of HEATR9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3243,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CD37 expression is observed. Does this perturbation lead to a significant difference in CD37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CD37 expression is observed. Does this perturbation lead to a significant difference in CD37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 62,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is quantified. Does this perturbation result in a significant change in RP11-662J14.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is quantified. Does this perturbation result in a significant change in RP11-662J14.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4840,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Does this perturbation cause a significant change in C19orf38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Does this perturbation cause a significant change in C19orf38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Determine whether H1FNT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Determine whether H1FNT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1473,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of C1orf162 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of C1orf162 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SLC22A25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SLC22A25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CD59. Does perturbing CDKN1A lead to a significant change in CD59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CD59. Does perturbing CDKN1A lead to a significant change in CD59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1733,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and RP11-195C7.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195C7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and RP11-195C7.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195C7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and TEX30 expression is measured. Determine whether TEX30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and TEX30 expression is measured. Determine whether TEX30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of SCG5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of SCG5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Determine whether DLX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Determine whether DLX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-290K4.2. Does this perturbation cause a significant change in RP11-290K4.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-290K4.2. Does this perturbation cause a significant change in RP11-290K4.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3393,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and CTB-49A3.5 expression is observed. Does this perturbation lead to a significant difference in CTB-49A3.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and CTB-49A3.5 expression is observed. Does this perturbation lead to a significant difference in CTB-49A3.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of NCF4. Does perturbing SET lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of NCF4. Does perturbing SET lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Does this perturbation cause a significant change in HIPK1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Does this perturbation cause a significant change in HIPK1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SLC2A1-AS1. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SLC2A1-AS1. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5053,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and COL1A1 expression is observed. Does this perturbation lead to a significant difference in COL1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and COL1A1 expression is observed. Does this perturbation lead to a significant difference in COL1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 583,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ETS1 expression is observed. Does this perturbation lead to a significant difference in ETS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ETS1 expression is observed. Does this perturbation lead to a significant difference in ETS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and C1orf141 expression is measured. Determine whether C1orf141 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and C1orf141 expression is measured. Determine whether C1orf141 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of SLC7A11. Does perturbing NCL lead to a significant change in SLC7A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of SLC7A11. Does perturbing NCL lead to a significant change in SLC7A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 693,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SOCS2 expression is observed. Does this perturbation lead to a significant difference in SOCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SOCS2 expression is observed. Does this perturbation lead to a significant difference in SOCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and SLC43A2 expression is quantified. Does this perturbation result in a significant change in SLC43A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and SLC43A2 expression is quantified. Does this perturbation result in a significant change in SLC43A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3658,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Determine whether TMEM154 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Determine whether TMEM154 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of RP11-445F12.1. Does perturbing BAK1 lead to a significant change in RP11-445F12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of RP11-445F12.1. Does perturbing BAK1 lead to a significant change in RP11-445F12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2893,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and FAM46C expression is observed. Does this perturbation lead to a significant difference in FAM46C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and FAM46C expression is observed. Does this perturbation lead to a significant difference in FAM46C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PPFIA4 expression is quantified. Does this perturbation result in a significant change in PPFIA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PPFIA4 expression is quantified. Does this perturbation result in a significant change in PPFIA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in PERM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in PERM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of APOBR. Does perturbing STIL lead to a significant change in APOBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of APOBR. Does perturbing STIL lead to a significant change in APOBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of VASH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of VASH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ACE. Does perturbing PRTG lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ACE. Does perturbing PRTG lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Determine whether CTD-2012K14.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Determine whether CTD-2012K14.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and LINC01338 expression is measured. Determine whether LINC01338 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and LINC01338 expression is measured. Determine whether LINC01338 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of PGA4. Does this perturbation cause a significant change in PGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of PGA4. Does this perturbation cause a significant change in PGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and S100A1 expression is quantified. Does this perturbation result in a significant change in S100A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and S100A1 expression is quantified. Does this perturbation result in a significant change in S100A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of UNC5B. Does perturbing CLDN6 lead to a significant change in UNC5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of UNC5B. Does perturbing CLDN6 lead to a significant change in UNC5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and RLN3 expression is quantified. Does this perturbation result in a significant change in RLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and RLN3 expression is quantified. Does this perturbation result in a significant change in RLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2970,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Does this perturbation cause a significant change in TCAF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Does this perturbation cause a significant change in TCAF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Determine whether KRTAP9-9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Determine whether KRTAP9-9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA5. Does perturbing MAPK1 lead to a significant change in ANXA5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA5. Does perturbing MAPK1 lead to a significant change in ANXA5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of S100A4. Does this perturbation cause a significant change in S100A4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of S100A4. Does this perturbation cause a significant change in S100A4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4320,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of AMPH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of AMPH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in N4BP2L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in N4BP2L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of MMP19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of MMP19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 100,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Does this perturbation cause a significant change in PSMB8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Does this perturbation cause a significant change in PSMB8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in RHOXF2BB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in RHOXF2BB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Determine whether CCNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Determine whether CCNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Determine whether BMP2K shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Determine whether BMP2K shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and EGOT expression is quantified. Does this perturbation result in a significant change in EGOT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and EGOT expression is quantified. Does this perturbation result in a significant change in EGOT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of TCAF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of TCAF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RP11-285F7.2. Does perturbing NCL lead to a significant change in RP11-285F7.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RP11-285F7.2. Does perturbing NCL lead to a significant change in RP11-285F7.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 768,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RP11-308D13.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-308D13.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RP11-308D13.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-308D13.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of RP11-442O1.4. Does this perturbation cause a significant change in RP11-442O1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of RP11-442O1.4. Does this perturbation cause a significant change in RP11-442O1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNDC3B. Does perturbing FOSB lead to a significant change in RUNDC3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNDC3B. Does perturbing FOSB lead to a significant change in RUNDC3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Determine whether CD37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Determine whether CD37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Determine whether GPR157 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Determine whether GPR157 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 970,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1970,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of RETN. Does this perturbation cause a significant change in RETN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of RETN. Does this perturbation cause a significant change in RETN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLA2G1B expression is measured. Determine whether PLA2G1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLA2G1B expression is measured. Determine whether PLA2G1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and HSD17B4 expression is measured. Determine whether HSD17B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and HSD17B4 expression is measured. Determine whether HSD17B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of IFIT2. Does this perturbation cause a significant change in IFIT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of IFIT2. Does this perturbation cause a significant change in IFIT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1523,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and SLC22A11 expression is measured. Determine whether SLC22A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and SLC22A11 expression is measured. Determine whether SLC22A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CYP1B1-AS1. Does perturbing HNF4A lead to a significant change in CYP1B1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CYP1B1-AS1. Does perturbing HNF4A lead to a significant change in CYP1B1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 373,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TUBA1A. Does this perturbation cause a significant change in TUBA1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TUBA1A. Does this perturbation cause a significant change in TUBA1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in MYL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in MYL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-109E24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-109E24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Determine whether LINC01395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Determine whether LINC01395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Determine whether RP11-202A13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Determine whether RP11-202A13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is measured. Determine whether CACNA1C-AS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is measured. Determine whether CACNA1C-AS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in RPS6KA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in RPS6KA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Determine whether TMEM55A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Determine whether TMEM55A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ANXA3 expression is measured. Determine whether ANXA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ANXA3 expression is measured. Determine whether ANXA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of H1FNT. Does this perturbation cause a significant change in H1FNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of H1FNT. Does this perturbation cause a significant change in H1FNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2220,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of HBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of HBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Determine whether PTRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Determine whether PTRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5950,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Does this perturbation cause a significant change in RUNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Does this perturbation cause a significant change in RUNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4740,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Does this perturbation cause a significant change in ICAM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Does this perturbation cause a significant change in ICAM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP11-345P4.7. Does perturbing MAPK1 lead to a significant change in RP11-345P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP11-345P4.7. Does perturbing MAPK1 lead to a significant change in RP11-345P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CCDC159. Does perturbing CEBPA lead to a significant change in CCDC159 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CCDC159. Does perturbing CEBPA lead to a significant change in CCDC159 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PTRF expression is quantified. Does this perturbation result in a significant change in PTRF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PTRF expression is quantified. Does this perturbation result in a significant change in PTRF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of TOX. Does perturbing MAP4K5 lead to a significant change in TOX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of TOX. Does perturbing MAP4K5 lead to a significant change in TOX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6240,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of TRPM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of TRPM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and SEMA3B expression is quantified. Does this perturbation result in a significant change in SEMA3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and SEMA3B expression is quantified. Does this perturbation result in a significant change in SEMA3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of COL21A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of COL21A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Determine whether FNDC3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Determine whether FNDC3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 143,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and HSD17B4 expression is observed. Does this perturbation lead to a significant difference in HSD17B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and HSD17B4 expression is observed. Does this perturbation lead to a significant difference in HSD17B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5903,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and STRC expression is observed. Does this perturbation lead to a significant difference in STRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and STRC expression is observed. Does this perturbation lead to a significant difference in STRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2433,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ZNF610 expression is observed. Does this perturbation lead to a significant difference in ZNF610 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ZNF610 expression is observed. Does this perturbation lead to a significant difference in ZNF610 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of IL1RN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of IL1RN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 443,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and HBE1 expression is observed. Does this perturbation lead to a significant difference in HBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and HBE1 expression is observed. Does this perturbation lead to a significant difference in HBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and MYL4 expression is measured. Determine whether MYL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and MYL4 expression is measured. Determine whether MYL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in DRC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in DRC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6023,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and IFIT2 expression is observed. Does this perturbation lead to a significant difference in IFIT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and IFIT2 expression is observed. Does this perturbation lead to a significant difference in IFIT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of SOX5. Does this perturbation cause a significant change in SOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of SOX5. Does this perturbation cause a significant change in SOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 81,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of CD52. Does perturbing MAML2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of CD52. Does perturbing MAML2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3778,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor RP1-59D14.10 expression. Decide whether this perturbation leads to a significant alteration in RP1-59D14.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor RP1-59D14.10 expression. Decide whether this perturbation leads to a significant alteration in RP1-59D14.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and TNFRSF12A expression is quantified. Does this perturbation result in a significant change in TNFRSF12A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and TNFRSF12A expression is quantified. Does this perturbation result in a significant change in TNFRSF12A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 838,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor RP11-968A15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-968A15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor RP11-968A15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-968A15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and TNFAIP8 expression is measured. Determine whether TNFAIP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and TNFAIP8 expression is measured. Determine whether TNFAIP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is quantified. Does this perturbation result in a significant change in RP11-510J16.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is quantified. Does this perturbation result in a significant change in RP11-510J16.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 240,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of SLC7A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of SLC7A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5828,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ARHGEF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ARHGEF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4318,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CYP1B1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP1B1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CYP1B1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP1B1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5793,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RP4-550H1.4 expression is observed. Does this perturbation lead to a significant difference in RP4-550H1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RP4-550H1.4 expression is observed. Does this perturbation lead to a significant difference in RP4-550H1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and CCDC136 expression is measured. Determine whether CCDC136 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and CCDC136 expression is measured. Determine whether CCDC136 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2400,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Does this perturbation cause a significant change in SLC20A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Does this perturbation cause a significant change in SLC20A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5558,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor TLCD2 expression. Decide whether this perturbation leads to a significant alteration in TLCD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor TLCD2 expression. Decide whether this perturbation leads to a significant alteration in TLCD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of NCALD. Does this perturbation cause a significant change in NCALD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of NCALD. Does this perturbation cause a significant change in NCALD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and TAS1R1 expression is measured. Determine whether TAS1R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and TAS1R1 expression is measured. Determine whether TAS1R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in APOL6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in APOL6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in SH3BGRL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in SH3BGRL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in FMNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in FMNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in CTC-490E21.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in CTC-490E21.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of INHBE. Does this perturbation cause a significant change in INHBE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of INHBE. Does this perturbation cause a significant change in INHBE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of PKIG. Does perturbing DUSP9 lead to a significant change in PKIG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of PKIG. Does perturbing DUSP9 lead to a significant change in PKIG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of HBD. Does perturbing UBASH3A lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of HBD. Does perturbing UBASH3A lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Determine whether EGOT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Determine whether EGOT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of TOR3A. Does perturbing NIT1 lead to a significant change in TOR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of TOR3A. Does perturbing NIT1 lead to a significant change in TOR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5200,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Does this perturbation cause a significant change in TNFAIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Does this perturbation cause a significant change in TNFAIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3578,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Determine whether AK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Determine whether AK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and AMPH expression is quantified. Does this perturbation result in a significant change in AMPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and AMPH expression is quantified. Does this perturbation result in a significant change in AMPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and TNFRSF12A expression is measured. Determine whether TNFRSF12A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and TNFRSF12A expression is measured. Determine whether TNFRSF12A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5510,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MS4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MS4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2643,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and TUBB expression is observed. Does this perturbation lead to a significant difference in TUBB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and TUBB expression is observed. Does this perturbation lead to a significant difference in TUBB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5550,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Does this perturbation cause a significant change in TLCD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Does this perturbation cause a significant change in TLCD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and CNN2 expression is quantified. Does this perturbation result in a significant change in CNN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and CNN2 expression is quantified. Does this perturbation result in a significant change in CNN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and RP11-38J22.3 expression is quantified. Does this perturbation result in a significant change in RP11-38J22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and RP11-38J22.3 expression is quantified. Does this perturbation result in a significant change in RP11-38J22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3213,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Determine whether TAS2R9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Determine whether TAS2R9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and MYO1F expression is quantified. Does this perturbation result in a significant change in MYO1F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and MYO1F expression is quantified. Does this perturbation result in a significant change in MYO1F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of TOR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of TOR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 550,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of PPP4R4. Does this perturbation cause a significant change in PPP4R4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of PPP4R4. Does this perturbation cause a significant change in PPP4R4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of POC1B-GALNT4. Does perturbing RUNX1T1 lead to a significant change in POC1B-GALNT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of POC1B-GALNT4. Does perturbing RUNX1T1 lead to a significant change in POC1B-GALNT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Determine whether AC020571.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Determine whether AC020571.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5418,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor SLC31A2 expression. Decide whether this perturbation leads to a significant alteration in SLC31A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor SLC31A2 expression. Decide whether this perturbation leads to a significant alteration in SLC31A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of SH3BGRL. Does perturbing BCORL1 lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of SH3BGRL. Does perturbing BCORL1 lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLEKHO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLEKHO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-497G19.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-497G19.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in KRTAP9-9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in KRTAP9-9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4098,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4898,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor SLC7A11 expression. Decide whether this perturbation leads to a significant alteration in SLC7A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor SLC7A11 expression. Decide whether this perturbation leads to a significant alteration in SLC7A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ASIC4. Does perturbing MAP2K3 lead to a significant change in ASIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ASIC4. Does perturbing MAP2K3 lead to a significant change in ASIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is quantified. Does this perturbation result in a significant change in RP11-369K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is quantified. Does this perturbation result in a significant change in RP11-369K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Determine whether CEBPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Determine whether CEBPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and PROX1 expression is quantified. Does this perturbation result in a significant change in PROX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and PROX1 expression is quantified. Does this perturbation result in a significant change in PROX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4750,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and FAM225B expression is quantified. Does this perturbation result in a significant change in FAM225B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and FAM225B expression is quantified. Does this perturbation result in a significant change in FAM225B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in HOXB6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in HOXB6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2800,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Does this perturbation cause a significant change in RUNDC3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Does this perturbation cause a significant change in RUNDC3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of FLJ12825. Does perturbing CEBPE lead to a significant change in FLJ12825 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of FLJ12825. Does perturbing CEBPE lead to a significant change in FLJ12825 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1878,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C6orf1 expression. Decide whether this perturbation leads to a significant alteration in C6orf1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C6orf1 expression. Decide whether this perturbation leads to a significant alteration in C6orf1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of MAOB. Does this perturbation cause a significant change in MAOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of MAOB. Does this perturbation cause a significant change in MAOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of AC139099.6. Does this perturbation cause a significant change in AC139099.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of AC139099.6. Does this perturbation cause a significant change in AC139099.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 860,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Does this perturbation cause a significant change in CYP3A5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Does this perturbation cause a significant change in CYP3A5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Determine whether SLC43A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Determine whether SLC43A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RP11-83A24.2. Does this perturbation cause a significant change in RP11-83A24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RP11-83A24.2. Does this perturbation cause a significant change in RP11-83A24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3000,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4138,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ITGA3 expression. Decide whether this perturbation leads to a significant alteration in ITGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ITGA3 expression. Decide whether this perturbation leads to a significant alteration in ITGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and SP6 expression is measured. Determine whether SP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and SP6 expression is measured. Determine whether SP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of LEFTY1. Does this perturbation cause a significant change in LEFTY1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of LEFTY1. Does this perturbation cause a significant change in LEFTY1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM83F. Does this perturbation cause a significant change in FAM83F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM83F. Does this perturbation cause a significant change in FAM83F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of TNFRSF12A. Does perturbing LYL1 lead to a significant change in TNFRSF12A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of TNFRSF12A. Does perturbing LYL1 lead to a significant change in TNFRSF12A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3140,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Does this perturbation cause a significant change in CBL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Does this perturbation cause a significant change in CBL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of CEBPA. Does perturbing CBFA2T3 lead to a significant change in CEBPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of CEBPA. Does perturbing CBFA2T3 lead to a significant change in CEBPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Determine whether CTB-49A3.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Determine whether CTB-49A3.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5153,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of AC139099.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of AC139099.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Determine whether LRRTM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Determine whether LRRTM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2183,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and TNFAIP8 expression is observed. Does this perturbation lead to a significant difference in TNFAIP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and TNFAIP8 expression is observed. Does this perturbation lead to a significant difference in TNFAIP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1843,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and AC004051.2 expression is observed. Does this perturbation lead to a significant difference in AC004051.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and AC004051.2 expression is observed. Does this perturbation lead to a significant difference in AC004051.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1390,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1678,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor DEK expression. Decide whether this perturbation leads to a significant alteration in DEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor DEK expression. Decide whether this perturbation leads to a significant alteration in DEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3783,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of IL20. Does this perturbation cause a significant change in IL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of IL20. Does this perturbation cause a significant change in IL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2650,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and BMP2K expression is measured. Determine whether BMP2K exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and BMP2K expression is measured. Determine whether BMP2K exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 23,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is measured. Determine whether RP11-646I6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is measured. Determine whether RP11-646I6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6213,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-109E24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-109E24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-109E24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-109E24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and PRTN3 expression is quantified. Does this perturbation result in a significant change in PRTN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and PRTN3 expression is quantified. Does this perturbation result in a significant change in PRTN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of AC004540.4. Does this perturbation cause a significant change in AC004540.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of AC004540.4. Does this perturbation cause a significant change in AC004540.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4200,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 783,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Determine whether AC139099.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Determine whether AC139099.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6008,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor TACC1 expression. Decide whether this perturbation leads to a significant alteration in TACC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor TACC1 expression. Decide whether this perturbation leads to a significant alteration in TACC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5818,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of C19orf38. Does perturbing UBASH3A lead to a significant change in C19orf38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of C19orf38. Does perturbing UBASH3A lead to a significant change in C19orf38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of LHX1. Does perturbing BAK1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of LHX1. Does perturbing BAK1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1078,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-646I6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-646I6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-646I6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-646I6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5273,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4790,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Does this perturbation cause a significant change in PAMR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Does this perturbation cause a significant change in PAMR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Determine whether NUDC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Determine whether NUDC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2628,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor XK expression. Decide whether this perturbation leads to a significant alteration in XK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor XK expression. Decide whether this perturbation leads to a significant alteration in XK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of MOGAT2. Does this perturbation cause a significant change in MOGAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of MOGAT2. Does this perturbation cause a significant change in MOGAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of LPAR2. Does perturbing HOXB9 lead to a significant change in LPAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of LPAR2. Does perturbing HOXB9 lead to a significant change in LPAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in HMGA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in HMGA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6170,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Determine whether EMP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Determine whether EMP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1283,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and COTL1 expression is observed. Does this perturbation lead to a significant difference in COTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and COTL1 expression is observed. Does this perturbation lead to a significant difference in COTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1378,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor RP11-635N19.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-635N19.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor RP11-635N19.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-635N19.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of CBL. Does this perturbation cause a significant change in CBL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of CBL. Does this perturbation cause a significant change in CBL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5003,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and RLN3 expression is observed. Does this perturbation lead to a significant difference in RLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and RLN3 expression is observed. Does this perturbation lead to a significant difference in RLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5338,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor HIST1H3H expression. Decide whether this perturbation leads to a significant alteration in HIST1H3H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor HIST1H3H expression. Decide whether this perturbation leads to a significant alteration in HIST1H3H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of VASH1. Does perturbing FOXA3 lead to a significant change in VASH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of VASH1. Does perturbing FOXA3 lead to a significant change in VASH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SPANXN5 expression is measured. Determine whether SPANXN5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SPANXN5 expression is measured. Determine whether SPANXN5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of REEP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of REEP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of FNDC3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of FNDC3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of RP11-180M15.6. Does perturbing IGDCC3 lead to a significant change in RP11-180M15.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of RP11-180M15.6. Does perturbing IGDCC3 lead to a significant change in RP11-180M15.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-567N4.3. Does this perturbation cause a significant change in RP11-567N4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-567N4.3. Does this perturbation cause a significant change in RP11-567N4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Determine whether AC007193.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Determine whether AC007193.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01395 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01395 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4483,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5350,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Does this perturbation cause a significant change in GIPR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Does this perturbation cause a significant change in GIPR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM83F expression is measured. Determine whether FAM83F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM83F expression is measured. Determine whether FAM83F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 850,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and UNC5B expression is quantified. Does this perturbation result in a significant change in UNC5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and UNC5B expression is quantified. Does this perturbation result in a significant change in UNC5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 353,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CACNA1C-AS2 expression is observed. Does this perturbation lead to a significant difference in CACNA1C-AS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CACNA1C-AS2 expression is observed. Does this perturbation lead to a significant difference in CACNA1C-AS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4560,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of RP11-714G18.1. Does this perturbation cause a significant change in RP11-714G18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of RP11-714G18.1. Does this perturbation cause a significant change in RP11-714G18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and LINC00479 expression is measured. Determine whether LINC00479 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and LINC00479 expression is measured. Determine whether LINC00479 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1250,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Does this perturbation cause a significant change in RP11-497G19.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Does this perturbation cause a significant change in RP11-497G19.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and SP6 expression is quantified. Does this perturbation result in a significant change in SP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and SP6 expression is quantified. Does this perturbation result in a significant change in SP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1210,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Does this perturbation cause a significant change in AC020571.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Does this perturbation cause a significant change in AC020571.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 56,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of CSRNP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of CSRNP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ZMYND15 expression is measured. Determine whether ZMYND15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ZMYND15 expression is measured. Determine whether ZMYND15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of PRTN3. Does this perturbation cause a significant change in PRTN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of PRTN3. Does this perturbation cause a significant change in PRTN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CCNB1. Does this perturbation cause a significant change in CCNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CCNB1. Does this perturbation cause a significant change in CCNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and MYL4 expression is quantified. Does this perturbation result in a significant change in MYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and MYL4 expression is quantified. Does this perturbation result in a significant change in MYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of RP11-1085N6.3. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of RP11-1085N6.3. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 898,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor TAS2R9 expression. Decide whether this perturbation leads to a significant alteration in TAS2R9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor TAS2R9 expression. Decide whether this perturbation leads to a significant alteration in TAS2R9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3793,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Determine whether RUNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Determine whether RUNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of FAM49A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of FAM49A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of AK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of AK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 67,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of RP1-261G23.7. Does perturbing RHOXF2BB lead to a significant change in RP1-261G23.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of RP1-261G23.7. Does perturbing RHOXF2BB lead to a significant change in RP1-261G23.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and MYLIP expression is quantified. Does this perturbation result in a significant change in MYLIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and MYLIP expression is quantified. Does this perturbation result in a significant change in MYLIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ITGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ITGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of TAS1R1. Does perturbing FEV lead to a significant change in TAS1R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of TAS1R1. Does perturbing FEV lead to a significant change in TAS1R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2213,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and RP11-195B3.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195B3.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and RP11-195B3.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195B3.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of TAPBP. Does this perturbation cause a significant change in TAPBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of TAPBP. Does this perturbation cause a significant change in TAPBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of FABP3. Does perturbing BPGM lead to a significant change in FABP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of FABP3. Does perturbing BPGM lead to a significant change in FABP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and CTSS expression is measured. Determine whether CTSS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and CTSS expression is measured. Determine whether CTSS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Determine whether FMNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Determine whether FMNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CRYM. Does perturbing C3orf72 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CRYM. Does perturbing C3orf72 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in FILIP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in FILIP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of S100A1. Does perturbing AHR lead to a significant change in S100A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of S100A1. Does perturbing AHR lead to a significant change in S100A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2993,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and FZD6 expression is observed. Does this perturbation lead to a significant difference in FZD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and FZD6 expression is observed. Does this perturbation lead to a significant difference in FZD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 760,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Does this perturbation cause a significant change in RP11-308D13.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Does this perturbation cause a significant change in RP11-308D13.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5643,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 998,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 440,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Does this perturbation cause a significant change in HBE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Does this perturbation cause a significant change in HBE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-328J14.1. Does this perturbation cause a significant change in RP11-328J14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-328J14.1. Does this perturbation cause a significant change in RP11-328J14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Determine whether SPANXD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Determine whether SPANXD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2963,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4068,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PPFIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PPFIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1398,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5253,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and UCKL1-AS1 expression is observed. Does this perturbation lead to a significant difference in UCKL1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and UCKL1-AS1 expression is observed. Does this perturbation lead to a significant difference in UCKL1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1208,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ACP5 expression. Decide whether this perturbation leads to a significant alteration in ACP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ACP5 expression. Decide whether this perturbation leads to a significant alteration in ACP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of PERM1. Does this perturbation cause a significant change in PERM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of PERM1. Does this perturbation cause a significant change in PERM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in KRT79 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in KRT79 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ATG2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ATG2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and HOXB6 expression is quantified. Does this perturbation result in a significant change in HOXB6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and HOXB6 expression is quantified. Does this perturbation result in a significant change in HOXB6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CD59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CD59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2058,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is measured. Determine whether RP1-261G23.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is measured. Determine whether RP1-261G23.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 383,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CPXM1 expression is observed. Does this perturbation lead to a significant difference in CPXM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CPXM1 expression is observed. Does this perturbation lead to a significant difference in CPXM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ACSL1 expression is quantified. Does this perturbation result in a significant change in ACSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ACSL1 expression is quantified. Does this perturbation result in a significant change in ACSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5113,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and KCNQ1-AS1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and KCNQ1-AS1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and CCNB2 expression is quantified. Does this perturbation result in a significant change in CCNB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and CCNB2 expression is quantified. Does this perturbation result in a significant change in CCNB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5660,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Does this perturbation cause a significant change in DRC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Does this perturbation cause a significant change in DRC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and C19orf38 expression is quantified. Does this perturbation result in a significant change in C19orf38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and C19orf38 expression is quantified. Does this perturbation result in a significant change in C19orf38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of DST. Does perturbing CDKN1A lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of DST. Does perturbing CDKN1A lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5410,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Does this perturbation cause a significant change in SLC31A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Does this perturbation cause a significant change in SLC31A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3848,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and CAPG expression is measured. Determine whether CAPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and CAPG expression is measured. Determine whether CAPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 290,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Does this perturbation cause a significant change in RP4-565E6.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Does this perturbation cause a significant change in RP4-565E6.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4498,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor TTC9B expression. Decide whether this perturbation leads to a significant alteration in TTC9B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor TTC9B expression. Decide whether this perturbation leads to a significant alteration in TTC9B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of HIST1H3H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of HIST1H3H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of RP11-537H15.3. Does this perturbation cause a significant change in RP11-537H15.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of RP11-537H15.3. Does this perturbation cause a significant change in RP11-537H15.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1833,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SLC22A25 expression is observed. Does this perturbation lead to a significant difference in SLC22A25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SLC22A25 expression is observed. Does this perturbation lead to a significant difference in SLC22A25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 78,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Determine whether GRAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Determine whether GRAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of RABAC1. Does this perturbation cause a significant change in RABAC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of RABAC1. Does this perturbation cause a significant change in RABAC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2380,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Does this perturbation cause a significant change in HEATR9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Does this perturbation cause a significant change in HEATR9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-128B16.3. Does this perturbation cause a significant change in RP11-128B16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-128B16.3. Does this perturbation cause a significant change in RP11-128B16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5833,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and FZD6 expression is quantified. Does this perturbation result in a significant change in FZD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and FZD6 expression is quantified. Does this perturbation result in a significant change in FZD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in XK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in XK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01395 expression is quantified. Does this perturbation result in a significant change in LINC01395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01395 expression is quantified. Does this perturbation result in a significant change in LINC01395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5483,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and PERM1 expression is observed. Does this perturbation lead to a significant difference in PERM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and PERM1 expression is observed. Does this perturbation lead to a significant difference in PERM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ADD3 expression is measured. Determine whether ADD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ADD3 expression is measured. Determine whether ADD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2808,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNDC3B expression. Decide whether this perturbation leads to a significant alteration in RUNDC3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNDC3B expression. Decide whether this perturbation leads to a significant alteration in RUNDC3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3150,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and VASH1 expression is measured. Determine whether VASH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and VASH1 expression is measured. Determine whether VASH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and DEK expression is quantified. Does this perturbation result in a significant change in DEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and DEK expression is quantified. Does this perturbation result in a significant change in DEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNDC3B expression is measured. Determine whether RUNDC3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNDC3B expression is measured. Determine whether RUNDC3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RP5-1142A6.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RP5-1142A6.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SLC22A25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SLC22A25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in H1FNT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in H1FNT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Determine whether CTD-2378E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Determine whether CTD-2378E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3923,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and GPR35 expression is observed. Does this perturbation lead to a significant difference in GPR35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and GPR35 expression is observed. Does this perturbation lead to a significant difference in GPR35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and FAM19A2 expression is measured. Determine whether FAM19A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and FAM19A2 expression is measured. Determine whether FAM19A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2273,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and RP11-537H15.3 expression is observed. Does this perturbation lead to a significant difference in RP11-537H15.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and RP11-537H15.3 expression is observed. Does this perturbation lead to a significant difference in RP11-537H15.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of LGALS12. Does perturbing DUSP9 lead to a significant change in LGALS12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of LGALS12. Does perturbing DUSP9 lead to a significant change in LGALS12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3290,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of TLCD2. Does this perturbation cause a significant change in TLCD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of TLCD2. Does this perturbation cause a significant change in TLCD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Determine whether N4BP2L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Determine whether N4BP2L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ADD3 expression is quantified. Does this perturbation result in a significant change in ADD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ADD3 expression is quantified. Does this perturbation result in a significant change in ADD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RP11-308D13.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RP11-308D13.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3318,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LRP10 expression. Decide whether this perturbation leads to a significant alteration in LRP10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LRP10 expression. Decide whether this perturbation leads to a significant alteration in LRP10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of MT1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of MT1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3478,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor AC139099.6 expression. Decide whether this perturbation leads to a significant alteration in AC139099.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor AC139099.6 expression. Decide whether this perturbation leads to a significant alteration in AC139099.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of SSTR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of SSTR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2613,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ZIC4 expression is observed. Does this perturbation lead to a significant difference in ZIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ZIC4 expression is observed. Does this perturbation lead to a significant difference in ZIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in CEBPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in CEBPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and INHBE expression is quantified. Does this perturbation result in a significant change in INHBE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and INHBE expression is quantified. Does this perturbation result in a significant change in INHBE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2803,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNDC3B expression is observed. Does this perturbation lead to a significant difference in RUNDC3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNDC3B expression is observed. Does this perturbation lead to a significant difference in RUNDC3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CACNA1C-AS2. Does perturbing FOXA1 lead to a significant change in CACNA1C-AS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CACNA1C-AS2. Does perturbing FOXA1 lead to a significant change in CACNA1C-AS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Determine whether PHACTR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Determine whether PHACTR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ATP8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ATP8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CITED2. Does perturbing HNF4A lead to a significant change in CITED2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CITED2. Does perturbing HNF4A lead to a significant change in CITED2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6140,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Does this perturbation cause a significant change in CCNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Does this perturbation cause a significant change in CCNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1480,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CTD-2311M21.3. Does perturbing BCORL1 lead to a significant change in CTD-2311M21.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CTD-2311M21.3. Does perturbing BCORL1 lead to a significant change in CTD-2311M21.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2598,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SPANXN5. Does this perturbation cause a significant change in SPANXN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SPANXN5. Does this perturbation cause a significant change in SPANXN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4928,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor BCL2L11 expression. Decide whether this perturbation leads to a significant alteration in BCL2L11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor BCL2L11 expression. Decide whether this perturbation leads to a significant alteration in BCL2L11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of RP11-968A15.2. Does perturbing ETS2 lead to a significant change in RP11-968A15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of RP11-968A15.2. Does perturbing ETS2 lead to a significant change in RP11-968A15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1698,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor FMNL1 expression. Decide whether this perturbation leads to a significant alteration in FMNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor FMNL1 expression. Decide whether this perturbation leads to a significant alteration in FMNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is measured. Determine whether RP11-1085N6.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is measured. Determine whether RP11-1085N6.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is quantified. Does this perturbation result in a significant change in RP5-1142A6.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is quantified. Does this perturbation result in a significant change in RP5-1142A6.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Determine whether RP11-497G19.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Determine whether RP11-497G19.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CCNL1 expression is quantified. Does this perturbation result in a significant change in CCNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CCNL1 expression is quantified. Does this perturbation result in a significant change in CCNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in TMEM88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in TMEM88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of GRAP2. Does this perturbation cause a significant change in GRAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of GRAP2. Does this perturbation cause a significant change in GRAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of RP3-525N10.2. Does this perturbation cause a significant change in RP3-525N10.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of RP3-525N10.2. Does this perturbation cause a significant change in RP3-525N10.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of AC006262.5. Does perturbing ZC3HAV1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of AC006262.5. Does perturbing ZC3HAV1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 85,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1380,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Determine whether C1orf228 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Determine whether C1orf228 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and DSC1 expression is quantified. Does this perturbation result in a significant change in DSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and DSC1 expression is quantified. Does this perturbation result in a significant change in DSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in KCNQ1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in KCNQ1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is quantified. Does this perturbation result in a significant change in RP11-6D1.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is quantified. Does this perturbation result in a significant change in RP11-6D1.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 273,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and STAC3 expression is observed. Does this perturbation lead to a significant difference in STAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and STAC3 expression is observed. Does this perturbation lead to a significant difference in STAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of RP11-362K14.7. Does this perturbation cause a significant change in RP11-362K14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of RP11-362K14.7. Does this perturbation cause a significant change in RP11-362K14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4788,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor RP11-202A13.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-202A13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor RP11-202A13.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-202A13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of BST2. Does perturbing PTPN13 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of BST2. Does perturbing PTPN13 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3788,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LRRTM4. Does this perturbation cause a significant change in LRRTM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LRRTM4. Does this perturbation cause a significant change in LRRTM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ADGRF1. Does this perturbation cause a significant change in ADGRF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ADGRF1. Does this perturbation cause a significant change in ADGRF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SLC2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SLC2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of RP11-635N19.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of RP11-635N19.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and GPR35 expression is measured. Determine whether GPR35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and GPR35 expression is measured. Determine whether GPR35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1168,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of BCL2L11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of BCL2L11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4418,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CTD-2527I21.14 expression. Decide whether this perturbation leads to a significant alteration in CTD-2527I21.14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CTD-2527I21.14 expression. Decide whether this perturbation leads to a significant alteration in CTD-2527I21.14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of PROX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of PROX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Determine whether RP11-320G24.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Determine whether RP11-320G24.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 950,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Does this perturbation cause a significant change in TRGVA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Does this perturbation cause a significant change in TRGVA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of RHOXF2BB. Does this perturbation cause a significant change in RHOXF2BB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of RHOXF2BB. Does this perturbation cause a significant change in RHOXF2BB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4490,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Does this perturbation cause a significant change in TTC9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Does this perturbation cause a significant change in TTC9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4570,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is measured. Determine whether RP11-635N19.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is measured. Determine whether RP11-635N19.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and LEFTY1 expression is measured. Determine whether LEFTY1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and LEFTY1 expression is measured. Determine whether LEFTY1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5028,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and LGALS12 expression is measured. Determine whether LGALS12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and LGALS12 expression is measured. Determine whether LGALS12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and CRABP2 expression is measured. Determine whether CRABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and CRABP2 expression is measured. Determine whether CRABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of MAOB. Does perturbing SLC6A9 lead to a significant change in MAOB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of MAOB. Does perturbing SLC6A9 lead to a significant change in MAOB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and IFIT2 expression is measured. Determine whether IFIT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and IFIT2 expression is measured. Determine whether IFIT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HHEX expression is measured. Determine whether HHEX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HHEX expression is measured. Determine whether HHEX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6270,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and NUMB expression is quantified. Does this perturbation result in a significant change in NUMB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and NUMB expression is quantified. Does this perturbation result in a significant change in NUMB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1280,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Does this perturbation cause a significant change in COTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Does this perturbation cause a significant change in COTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 803,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and C1orf162 expression is measured. Determine whether C1orf162 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and C1orf162 expression is measured. Determine whether C1orf162 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RNF168 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RNF168 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and CALY expression is measured. Determine whether CALY exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and CALY expression is measured. Determine whether CALY exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1883,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5178,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor APOBR expression. Decide whether this perturbation leads to a significant alteration in APOBR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor APOBR expression. Decide whether this perturbation leads to a significant alteration in APOBR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and SLC8A1 expression is quantified. Does this perturbation result in a significant change in SLC8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and SLC8A1 expression is quantified. Does this perturbation result in a significant change in SLC8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2580,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1223,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and TFRC expression is observed. Does this perturbation lead to a significant difference in TFRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and TFRC expression is observed. Does this perturbation lead to a significant difference in TFRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6148,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CCNL1 expression. Decide whether this perturbation leads to a significant alteration in CCNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CCNL1 expression. Decide whether this perturbation leads to a significant alteration in CCNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6268,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor MME expression. Decide whether this perturbation leads to a significant alteration in MME expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor MME expression. Decide whether this perturbation leads to a significant alteration in MME expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2118,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ARHGEF6 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ARHGEF6 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LRRTM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LRRTM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTD-3037G24.4. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTD-3037G24.4. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4278,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of CEBPD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of CEBPD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is measured. Determine whether PRKAG2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is measured. Determine whether PRKAG2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 32,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and PDE1B expression is quantified. Does this perturbation result in a significant change in PDE1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and PDE1B expression is quantified. Does this perturbation result in a significant change in PDE1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4868,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5658,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor RELB expression. Decide whether this perturbation leads to a significant alteration in RELB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor RELB expression. Decide whether this perturbation leads to a significant alteration in RELB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of C19orf38. Does this perturbation cause a significant change in C19orf38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of C19orf38. Does this perturbation cause a significant change in C19orf38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1920,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and SH3RF2 expression is measured. Determine whether SH3RF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and SH3RF2 expression is measured. Determine whether SH3RF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and MYO1F expression is measured. Determine whether MYO1F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and MYO1F expression is measured. Determine whether MYO1F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CIB3. Does perturbing CEBPB lead to a significant change in CIB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CIB3. Does perturbing CEBPB lead to a significant change in CIB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of COTL1. Does this perturbation cause a significant change in COTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of COTL1. Does this perturbation cause a significant change in COTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3080,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Determine whether SLC31A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Determine whether SLC31A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SKAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SKAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5348,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor TOR3A expression. Decide whether this perturbation leads to a significant alteration in TOR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor TOR3A expression. Decide whether this perturbation leads to a significant alteration in TOR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of FZD6. Does this perturbation cause a significant change in FZD6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of FZD6. Does this perturbation cause a significant change in FZD6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5840,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Does this perturbation cause a significant change in LRRTM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Does this perturbation cause a significant change in LRRTM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and BCL2L11 expression is quantified. Does this perturbation result in a significant change in BCL2L11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and BCL2L11 expression is quantified. Does this perturbation result in a significant change in BCL2L11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4033,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and MSX1 expression is observed. Does this perturbation lead to a significant difference in MSX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and MSX1 expression is observed. Does this perturbation lead to a significant difference in MSX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2113,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ARHGEF6 expression is observed. Does this perturbation lead to a significant difference in ARHGEF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ARHGEF6 expression is observed. Does this perturbation lead to a significant difference in ARHGEF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLEKHO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLEKHO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of NKG7. Does perturbing ISL2 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of NKG7. Does perturbing ISL2 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Determine whether MYC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Determine whether MYC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of CBL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of CBL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1040,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Does this perturbation cause a significant change in S100A4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Does this perturbation cause a significant change in S100A4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3173,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and SSTR3 expression is observed. Does this perturbation lead to a significant difference in SSTR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and SSTR3 expression is observed. Does this perturbation lead to a significant difference in SSTR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3740,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is measured. Determine whether HIPK1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is measured. Determine whether HIPK1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5390,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLA2G16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLA2G16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 360,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Does this perturbation cause a significant change in MT1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Does this perturbation cause a significant change in MT1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4303,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and SLC22A11 expression is observed. Does this perturbation lead to a significant difference in SLC22A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and SLC22A11 expression is observed. Does this perturbation lead to a significant difference in SLC22A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6273,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CTD-2378E12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2378E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CTD-2378E12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2378E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5353,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and GIPR expression is observed. Does this perturbation lead to a significant difference in GIPR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and GIPR expression is observed. Does this perturbation lead to a significant difference in GIPR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Determine whether TFAP2A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Determine whether TFAP2A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is measured. Determine whether RP3-525N10.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is measured. Determine whether RP3-525N10.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AC007246.3 expression is quantified. Does this perturbation result in a significant change in AC007246.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AC007246.3 expression is quantified. Does this perturbation result in a significant change in AC007246.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-1017G21.6. Does perturbing ARRDC3 lead to a significant change in RP11-1017G21.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-1017G21.6. Does perturbing ARRDC3 lead to a significant change in RP11-1017G21.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2088,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ACTB expression. Decide whether this perturbation leads to a significant alteration in ACTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ACTB expression. Decide whether this perturbation leads to a significant alteration in ACTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ST3GAL5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ST3GAL5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of IER3. Does perturbing FOSB lead to a significant change in IER3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of IER3. Does perturbing FOSB lead to a significant change in IER3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of CCR10. Does perturbing SLC6A9 lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of CCR10. Does perturbing SLC6A9 lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of AC007556.3. Does perturbing ETS2 lead to a significant change in AC007556.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of AC007556.3. Does perturbing ETS2 lead to a significant change in AC007556.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 788,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD47 expression. Decide whether this perturbation leads to a significant alteration in CD47 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD47 expression. Decide whether this perturbation leads to a significant alteration in CD47 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4603,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TMEM55A expression is observed. Does this perturbation lead to a significant difference in TMEM55A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TMEM55A expression is observed. Does this perturbation lead to a significant difference in TMEM55A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3053,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and GPR157 expression is observed. Does this perturbation lead to a significant difference in GPR157 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and GPR157 expression is observed. Does this perturbation lead to a significant difference in GPR157 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-505P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-505P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and HOXB6 expression is measured. Determine whether HOXB6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and HOXB6 expression is measured. Determine whether HOXB6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3148,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor CBL expression. Decide whether this perturbation leads to a significant alteration in CBL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor CBL expression. Decide whether this perturbation leads to a significant alteration in CBL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TRIM31 expression is measured. Determine whether TRIM31 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TRIM31 expression is measured. Determine whether TRIM31 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ARPC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ARPC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and VCX3B expression is measured. Determine whether VCX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and VCX3B expression is measured. Determine whether VCX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2173,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and PXK expression is observed. Does this perturbation lead to a significant difference in PXK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and PXK expression is observed. Does this perturbation lead to a significant difference in PXK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of KCNQ1-AS1. Does perturbing SPI1 lead to a significant change in KCNQ1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of KCNQ1-AS1. Does perturbing SPI1 lead to a significant change in KCNQ1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4653,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LRRC74B expression is observed. Does this perturbation lead to a significant difference in LRRC74B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LRRC74B expression is observed. Does this perturbation lead to a significant difference in LRRC74B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ARL6IP1 expression is quantified. Does this perturbation result in a significant change in ARL6IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ARL6IP1 expression is quantified. Does this perturbation result in a significant change in ARL6IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CITED2 expression is quantified. Does this perturbation result in a significant change in CITED2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CITED2 expression is quantified. Does this perturbation result in a significant change in CITED2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4913,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RIT1 expression is observed. Does this perturbation lead to a significant difference in RIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RIT1 expression is observed. Does this perturbation lead to a significant difference in RIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4433,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and RP11-180M15.6 expression is observed. Does this perturbation lead to a significant difference in RP11-180M15.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and RP11-180M15.6 expression is observed. Does this perturbation lead to a significant difference in RP11-180M15.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CFH. Does perturbing TGFBR2 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CFH. Does perturbing TGFBR2 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C6orf1. Does this perturbation cause a significant change in C6orf1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C6orf1. Does this perturbation cause a significant change in C6orf1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1038,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PTRF expression. Decide whether this perturbation leads to a significant alteration in PTRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PTRF expression. Decide whether this perturbation leads to a significant alteration in PTRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and FNDC3A expression is quantified. Does this perturbation result in a significant change in FNDC3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and FNDC3A expression is quantified. Does this perturbation result in a significant change in FNDC3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of FABP3. Does this perturbation cause a significant change in FABP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of FABP3. Does this perturbation cause a significant change in FABP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of RP11-362K14.7. Does perturbing KIAA1804 lead to a significant change in RP11-362K14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of RP11-362K14.7. Does perturbing KIAA1804 lead to a significant change in RP11-362K14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 940,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Does this perturbation cause a significant change in MMP19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Does this perturbation cause a significant change in MMP19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of RP11-195B3.1. Does perturbing CELF2 lead to a significant change in RP11-195B3.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of RP11-195B3.1. Does perturbing CELF2 lead to a significant change in RP11-195B3.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1488,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CREB3L2 expression is measured. Determine whether CREB3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CREB3L2 expression is measured. Determine whether CREB3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1060,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Does this perturbation cause a significant change in RP11-510J16.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Does this perturbation cause a significant change in RP11-510J16.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RNF168 expression is measured. Determine whether RNF168 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RNF168 expression is measured. Determine whether RNF168 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-497G19.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-497G19.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RGPD5. Does perturbing CITED1 lead to a significant change in RGPD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RGPD5. Does perturbing CITED1 lead to a significant change in RGPD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1100,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Does this perturbation cause a significant change in PRTN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Does this perturbation cause a significant change in PRTN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5043,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ABCA13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ABCA13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1293,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and DSC1 expression is observed. Does this perturbation lead to a significant difference in DSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and DSC1 expression is observed. Does this perturbation lead to a significant difference in DSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in CSRNP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in CSRNP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 218,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Determine whether SPARC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Determine whether SPARC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MS4A2 expression is quantified. Does this perturbation result in a significant change in MS4A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MS4A2 expression is quantified. Does this perturbation result in a significant change in MS4A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 433,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-128B16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-128B16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4190,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Does this perturbation cause a significant change in SPANXD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Does this perturbation cause a significant change in SPANXD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in SIGLEC15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in SIGLEC15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3333,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and CST9L expression is observed. Does this perturbation lead to a significant difference in CST9L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and CST9L expression is observed. Does this perturbation lead to a significant difference in CST9L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2358,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor SOX4 expression. Decide whether this perturbation leads to a significant alteration in SOX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor SOX4 expression. Decide whether this perturbation leads to a significant alteration in SOX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4818,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of PRKAG2-AS1. Does perturbing HOXC13 lead to a significant change in PRKAG2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of PRKAG2-AS1. Does perturbing HOXC13 lead to a significant change in PRKAG2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3973,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ARMCX3 expression is observed. Does this perturbation lead to a significant difference in ARMCX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ARMCX3 expression is observed. Does this perturbation lead to a significant difference in ARMCX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Determine whether CCNJL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Determine whether CCNJL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6108,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 61,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of AVP. Does perturbing MAML2 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of AVP. Does perturbing MAML2 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2523,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in RSPO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in RSPO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3590,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Does this perturbation cause a significant change in TUBB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Does this perturbation cause a significant change in TUBB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of UBE2H. Does perturbing CDKN1A lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of UBE2H. Does perturbing CDKN1A lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FAM83A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FAM83A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and LPAR2 expression is measured. Determine whether LPAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and LPAR2 expression is measured. Determine whether LPAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTD-3037G24.4. Does perturbing UBASH3B lead to a significant change in CTD-3037G24.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTD-3037G24.4. Does perturbing UBASH3B lead to a significant change in CTD-3037G24.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3810,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Does this perturbation cause a significant change in RP11-563J2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Does this perturbation cause a significant change in RP11-563J2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HCN1. Does perturbing IKZF3 lead to a significant change in HCN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HCN1. Does perturbing IKZF3 lead to a significant change in HCN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Determine whether TMEM88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Determine whether TMEM88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and RBM5-AS1 expression is measured. Determine whether RBM5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and RBM5-AS1 expression is measured. Determine whether RBM5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of TNFAIP8. Does this perturbation cause a significant change in TNFAIP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of TNFAIP8. Does this perturbation cause a significant change in TNFAIP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of SP6. Does perturbing HES7 lead to a significant change in SP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of SP6. Does perturbing HES7 lead to a significant change in SP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-646I6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-646I6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2198,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor IL1RN expression. Decide whether this perturbation leads to a significant alteration in IL1RN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor IL1RN expression. Decide whether this perturbation leads to a significant alteration in IL1RN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Determine whether DEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Determine whether DEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 420,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ATP8A1 expression is measured. Determine whether ATP8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ATP8A1 expression is measured. Determine whether ATP8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2423,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SDSL expression is observed. Does this perturbation lead to a significant difference in SDSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SDSL expression is observed. Does this perturbation lead to a significant difference in SDSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is quantified. Does this perturbation result in a significant change in KCNQ1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is quantified. Does this perturbation result in a significant change in KCNQ1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RP11-285F7.2 expression is measured. Determine whether RP11-285F7.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RP11-285F7.2 expression is measured. Determine whether RP11-285F7.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4500,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SLC2A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SLC2A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5428,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01420 expression. Decide whether this perturbation leads to a significant alteration in LINC01420 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01420 expression. Decide whether this perturbation leads to a significant alteration in LINC01420 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and SLCO6A1 expression is measured. Determine whether SLCO6A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and SLCO6A1 expression is measured. Determine whether SLCO6A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and CPVL expression is measured. Determine whether CPVL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and CPVL expression is measured. Determine whether CPVL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Determine whether CDK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Determine whether CDK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and GRAP2 expression is quantified. Does this perturbation result in a significant change in GRAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and GRAP2 expression is quantified. Does this perturbation result in a significant change in GRAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4228,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor N4BP2L2 expression. Decide whether this perturbation leads to a significant alteration in N4BP2L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor N4BP2L2 expression. Decide whether this perturbation leads to a significant alteration in N4BP2L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HCN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HCN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNDC3B expression is quantified. Does this perturbation result in a significant change in RUNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNDC3B expression is quantified. Does this perturbation result in a significant change in RUNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2898,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor FAM46C expression. Decide whether this perturbation leads to a significant alteration in FAM46C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor FAM46C expression. Decide whether this perturbation leads to a significant alteration in FAM46C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of RP11-38J22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of RP11-38J22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 870,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1418,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in S100A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in S100A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of KCNQ1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of KCNQ1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and HBE1 expression is quantified. Does this perturbation result in a significant change in HBE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and HBE1 expression is quantified. Does this perturbation result in a significant change in HBE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1593,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and CALY expression is observed. Does this perturbation lead to a significant difference in CALY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and CALY expression is observed. Does this perturbation lead to a significant difference in CALY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 303,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2080,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Does this perturbation cause a significant change in ACTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Does this perturbation cause a significant change in ACTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Determine whether AREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Determine whether AREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of TEX30. Does this perturbation cause a significant change in TEX30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of TEX30. Does this perturbation cause a significant change in TEX30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4168,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CENPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CENPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in C1orf141 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in C1orf141 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is quantified. Does this perturbation result in a significant change in RP11-646I6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is quantified. Does this perturbation result in a significant change in RP11-646I6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Determine whether INADL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Determine whether INADL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5743,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of RP3-467K16.2. Does perturbing BCL2L11 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of RP3-467K16.2. Does perturbing BCL2L11 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1093,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 43,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP11-445O3.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445O3.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP11-445O3.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445O3.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is quantified. Does this perturbation result in a significant change in RP1-261G23.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is quantified. Does this perturbation result in a significant change in RP1-261G23.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in HIST1H3H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in HIST1H3H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ATP10D expression is quantified. Does this perturbation result in a significant change in ATP10D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ATP10D expression is quantified. Does this perturbation result in a significant change in ATP10D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5128,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor CCNJL expression. Decide whether this perturbation leads to a significant alteration in CCNJL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor CCNJL expression. Decide whether this perturbation leads to a significant alteration in CCNJL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6203,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-52L5.6 expression is observed. Does this perturbation lead to a significant difference in RP11-52L5.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-52L5.6 expression is observed. Does this perturbation lead to a significant difference in RP11-52L5.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in TAPBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in TAPBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in CTD-2616J11.16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in CTD-2616J11.16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Determine whether RP11-328J14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Determine whether RP11-328J14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Determine whether CALY shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Determine whether CALY shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2730,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Does this perturbation cause a significant change in ZMYND15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Does this perturbation cause a significant change in ZMYND15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and REEP6 expression is quantified. Does this perturbation result in a significant change in REEP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and REEP6 expression is quantified. Does this perturbation result in a significant change in REEP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of N4BP2L2. Does this perturbation cause a significant change in N4BP2L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of N4BP2L2. Does this perturbation cause a significant change in N4BP2L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1498,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor MAOB expression. Decide whether this perturbation leads to a significant alteration in MAOB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor MAOB expression. Decide whether this perturbation leads to a significant alteration in MAOB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of RABAC1. Does perturbing STIL lead to a significant change in RABAC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of RABAC1. Does perturbing STIL lead to a significant change in RABAC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in MSRB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in MSRB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4370,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and FCGR3A expression is quantified. Does this perturbation result in a significant change in FCGR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and FCGR3A expression is quantified. Does this perturbation result in a significant change in FCGR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MS4A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MS4A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1888,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor MTURN expression. Decide whether this perturbation leads to a significant alteration in MTURN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor MTURN expression. Decide whether this perturbation leads to a significant alteration in MTURN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of RP11-714G18.1. Does perturbing FOXO4 lead to a significant change in RP11-714G18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of RP11-714G18.1. Does perturbing FOXO4 lead to a significant change in RP11-714G18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4683,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2353,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and SOX4 expression is observed. Does this perturbation lead to a significant difference in SOX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and SOX4 expression is observed. Does this perturbation lead to a significant difference in SOX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Determine whether AIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Determine whether AIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD47 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD47 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of MOGAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of MOGAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and AC004540.4 expression is measured. Determine whether AC004540.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and AC004540.4 expression is measured. Determine whether AC004540.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and TFAP2A expression is measured. Determine whether TFAP2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and TFAP2A expression is measured. Determine whether TFAP2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Determine whether CYP2C18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Determine whether CYP2C18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of EMP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of EMP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of EGOT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of EGOT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ARRDC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ARRDC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is quantified. Does this perturbation result in a significant change in RP3-510H16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is quantified. Does this perturbation result in a significant change in RP3-510H16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4008,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor SLC22A13 expression. Decide whether this perturbation leads to a significant alteration in SLC22A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor SLC22A13 expression. Decide whether this perturbation leads to a significant alteration in SLC22A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and VMP1 expression is measured. Determine whether VMP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and VMP1 expression is measured. Determine whether VMP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5473,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and RP11-369K17.1 expression is observed. Does this perturbation lead to a significant difference in RP11-369K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and RP11-369K17.1 expression is observed. Does this perturbation lead to a significant difference in RP11-369K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and LPAR2 expression is quantified. Does this perturbation result in a significant change in LPAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and LPAR2 expression is quantified. Does this perturbation result in a significant change in LPAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6198,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CRAT37 expression. Decide whether this perturbation leads to a significant alteration in CRAT37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CRAT37 expression. Decide whether this perturbation leads to a significant alteration in CRAT37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of SLC7A11. Does this perturbation cause a significant change in SLC7A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of SLC7A11. Does this perturbation cause a significant change in SLC7A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIPK1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIPK1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of SLC31A2. Does perturbing CDKN1B lead to a significant change in SLC31A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of SLC31A2. Does perturbing CDKN1B lead to a significant change in SLC31A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 848,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ARPC3 expression. Decide whether this perturbation leads to a significant alteration in ARPC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ARPC3 expression. Decide whether this perturbation leads to a significant alteration in ARPC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in DYNLT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in DYNLT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Determine whether CD47 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Determine whether CD47 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and RELB expression is measured. Determine whether RELB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and RELB expression is measured. Determine whether RELB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3893,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and HMGA2 expression is observed. Does this perturbation lead to a significant difference in HMGA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and HMGA2 expression is observed. Does this perturbation lead to a significant difference in HMGA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of TEX30. Does perturbing PTPN1 lead to a significant change in TEX30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of TEX30. Does perturbing PTPN1 lead to a significant change in TEX30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1153,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1533,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and SLC43A2 expression is observed. Does this perturbation lead to a significant difference in SLC43A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and SLC43A2 expression is observed. Does this perturbation lead to a significant difference in SLC43A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CKS2 expression is quantified. Does this perturbation result in a significant change in CKS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CKS2 expression is quantified. Does this perturbation result in a significant change in CKS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LRRC74B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LRRC74B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LGALS1. Does perturbing CSRNP1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LGALS1. Does perturbing CSRNP1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2533,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SLC2A3 expression is observed. Does this perturbation lead to a significant difference in SLC2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SLC2A3 expression is observed. Does this perturbation lead to a significant difference in SLC2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is quantified. Does this perturbation result in a significant change in CTD-2616J11.16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is quantified. Does this perturbation result in a significant change in CTD-2616J11.16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Does this perturbation cause a significant change in SH3RF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Does this perturbation cause a significant change in SH3RF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Determine whether RP11-308D13.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Determine whether RP11-308D13.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and H1FNT expression is quantified. Does this perturbation result in a significant change in H1FNT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and H1FNT expression is quantified. Does this perturbation result in a significant change in H1FNT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 55,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and LBH expression is measured. Determine whether LBH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and LBH expression is measured. Determine whether LBH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5463,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4503,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of YPEL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of YPEL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of DSC1. Does this perturbation cause a significant change in DSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of DSC1. Does this perturbation cause a significant change in DSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CITED2. Does this perturbation cause a significant change in CITED2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CITED2. Does this perturbation cause a significant change in CITED2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of RP11-505P4.6. Does this perturbation cause a significant change in RP11-505P4.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of RP11-505P4.6. Does this perturbation cause a significant change in RP11-505P4.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and EWSAT1 expression is measured. Determine whether EWSAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and EWSAT1 expression is measured. Determine whether EWSAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5770,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of PRTN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of PRTN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is quantified. Does this perturbation result in a significant change in RP11-445F12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is quantified. Does this perturbation result in a significant change in RP11-445F12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-219B4.7 expression is measured. Determine whether RP11-219B4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-219B4.7 expression is measured. Determine whether RP11-219B4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Determine whether RASGRF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Determine whether RASGRF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in TUBB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in TUBB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ANTXR2. Does this perturbation cause a significant change in ANTXR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ANTXR2. Does this perturbation cause a significant change in ANTXR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2120,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Determine whether LBH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Determine whether LBH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5693,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and SLC38A2 expression is observed. Does this perturbation lead to a significant difference in SLC38A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and SLC38A2 expression is observed. Does this perturbation lead to a significant difference in SLC38A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of XK. Does this perturbation cause a significant change in XK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of XK. Does this perturbation cause a significant change in XK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4453,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RHOH expression is observed. Does this perturbation lead to a significant difference in RHOH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RHOH expression is observed. Does this perturbation lead to a significant difference in RHOH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and S100A1 expression is measured. Determine whether S100A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and S100A1 expression is measured. Determine whether S100A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1393,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Determine whether NUMB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Determine whether NUMB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ATG2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ATG2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 868,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CYP3A5 expression. Decide whether this perturbation leads to a significant alteration in CYP3A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CYP3A5 expression. Decide whether this perturbation leads to a significant alteration in CYP3A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 178,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor FLJ12825 expression. Decide whether this perturbation leads to a significant alteration in FLJ12825 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor FLJ12825 expression. Decide whether this perturbation leads to a significant alteration in FLJ12825 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of VCX3B. Does perturbing CEBPE lead to a significant change in VCX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of VCX3B. Does perturbing CEBPE lead to a significant change in VCX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and GPR157 expression is quantified. Does this perturbation result in a significant change in GPR157 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and GPR157 expression is quantified. Does this perturbation result in a significant change in GPR157 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4143,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and TMEM154 expression is observed. Does this perturbation lead to a significant difference in TMEM154 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and TMEM154 expression is observed. Does this perturbation lead to a significant difference in TMEM154 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 68,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIST1H2AC. Does perturbing CKS1B lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIST1H2AC. Does perturbing CKS1B lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2418,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor TEX30 expression. Decide whether this perturbation leads to a significant alteration in TEX30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor TEX30 expression. Decide whether this perturbation leads to a significant alteration in TEX30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Determine whether XK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Determine whether XK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 358,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CACNA1C-AS2 expression. Decide whether this perturbation leads to a significant alteration in CACNA1C-AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CACNA1C-AS2 expression. Decide whether this perturbation leads to a significant alteration in CACNA1C-AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6238,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 933,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CYP2C18 expression is observed. Does this perturbation lead to a significant difference in CYP2C18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CYP2C18 expression is observed. Does this perturbation lead to a significant difference in CYP2C18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in PRKAG2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in PRKAG2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4123,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and AC004540.4 expression is observed. Does this perturbation lead to a significant difference in AC004540.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and AC004540.4 expression is observed. Does this perturbation lead to a significant difference in AC004540.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLA2G1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLA2G1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in RP11-195C7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in RP11-195C7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and COL1A1 expression is quantified. Does this perturbation result in a significant change in COL1A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and COL1A1 expression is quantified. Does this perturbation result in a significant change in COL1A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and RIMBP3C expression is measured. Determine whether RIMBP3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and RIMBP3C expression is measured. Determine whether RIMBP3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Determine whether MKNK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Determine whether MKNK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TUBA1A expression is measured. Determine whether TUBA1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TUBA1A expression is measured. Determine whether TUBA1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2828,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP6-159A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP6-159A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP6-159A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP6-159A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2623,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and XK expression is observed. Does this perturbation lead to a significant difference in XK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and XK expression is observed. Does this perturbation lead to a significant difference in XK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 13,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and CLU expression is observed. Does this perturbation lead to a significant difference in CLU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and CLU expression is observed. Does this perturbation lead to a significant difference in CLU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ANTXR2. Does perturbing ZBTB10 lead to a significant change in ANTXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ANTXR2. Does perturbing ZBTB10 lead to a significant change in ANTXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in TNFRSF12A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in TNFRSF12A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CYP1B1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CYP1B1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Determine whether ABCA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Determine whether ABCA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of AREG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of AREG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 90,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Does this perturbation cause a significant change in TDRD12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Does this perturbation cause a significant change in TDRD12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of CEBPD. Does this perturbation cause a significant change in CEBPD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of CEBPD. Does this perturbation cause a significant change in CEBPD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4623,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and SOX5 expression is quantified. Does this perturbation result in a significant change in SOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and SOX5 expression is quantified. Does this perturbation result in a significant change in SOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of MSX1. Does this perturbation cause a significant change in MSX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of MSX1. Does this perturbation cause a significant change in MSX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5940,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1243,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-259K5.1 expression is observed. Does this perturbation lead to a significant difference in RP11-259K5.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-259K5.1 expression is observed. Does this perturbation lead to a significant difference in RP11-259K5.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3558,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4910,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Does this perturbation cause a significant change in RIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Does this perturbation cause a significant change in RIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4368,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TFAP2A-AS1 expression. Decide whether this perturbation leads to a significant alteration in TFAP2A-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TFAP2A-AS1 expression. Decide whether this perturbation leads to a significant alteration in TFAP2A-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM83F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM83F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of STAC3. Does this perturbation cause a significant change in STAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of STAC3. Does this perturbation cause a significant change in STAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Determine whether MT1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Determine whether MT1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and MME expression is quantified. Does this perturbation result in a significant change in MME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and MME expression is quantified. Does this perturbation result in a significant change in MME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4583,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of AC144568.2. Does this perturbation cause a significant change in AC144568.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of AC144568.2. Does this perturbation cause a significant change in AC144568.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Determine whether MOGAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Determine whether MOGAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Determine whether LINC01003 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Determine whether LINC01003 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in MKNK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in MKNK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Determine whether ZMAT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Determine whether ZMAT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PAMR1. Does this perturbation cause a significant change in PAMR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PAMR1. Does this perturbation cause a significant change in PAMR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ATG2A expression is quantified. Does this perturbation result in a significant change in ATG2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ATG2A expression is quantified. Does this perturbation result in a significant change in ATG2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Determine whether GIPR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Determine whether GIPR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Determine whether CCDC159 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Determine whether CCDC159 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of UCKL1-AS1. Does this perturbation cause a significant change in UCKL1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of UCKL1-AS1. Does this perturbation cause a significant change in UCKL1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of RP1-261G23.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of RP1-261G23.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of RELB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of RELB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 57,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCM2L. Does perturbing CNN1 lead to a significant change in CCM2L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCM2L. Does perturbing CNN1 lead to a significant change in CCM2L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of CEBPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of CEBPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Determine whether CD59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Determine whether CD59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in CTSW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in CTSW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of BLVRB. Does perturbing CNN1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of BLVRB. Does perturbing CNN1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and DCAF13 expression is quantified. Does this perturbation result in a significant change in DCAF13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and DCAF13 expression is quantified. Does this perturbation result in a significant change in DCAF13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and MYC expression is quantified. Does this perturbation result in a significant change in MYC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and MYC expression is quantified. Does this perturbation result in a significant change in MYC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and S100A4 expression is quantified. Does this perturbation result in a significant change in S100A4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and S100A4 expression is quantified. Does this perturbation result in a significant change in S100A4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and MSX1 expression is measured. Determine whether MSX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and MSX1 expression is measured. Determine whether MSX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4288,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CITED2 expression. Decide whether this perturbation leads to a significant alteration in CITED2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CITED2 expression. Decide whether this perturbation leads to a significant alteration in CITED2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 618,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5588,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ANTXR2 expression. Decide whether this perturbation leads to a significant alteration in ANTXR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ANTXR2 expression. Decide whether this perturbation leads to a significant alteration in ANTXR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2678,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor DYNLT3 expression. Decide whether this perturbation leads to a significant alteration in DYNLT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor DYNLT3 expression. Decide whether this perturbation leads to a significant alteration in DYNLT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 280,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Does this perturbation cause a significant change in CRABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Does this perturbation cause a significant change in CRABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Determine whether TCAF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Determine whether TCAF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4578,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in TM4SF1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in TM4SF1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Determine whether LPAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Determine whether LPAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1613,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of C10orf11. Does perturbing CBFA2T3 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of C10orf11. Does perturbing CBFA2T3 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5333,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and HIST1H3H expression is observed. Does this perturbation lead to a significant difference in HIST1H3H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and HIST1H3H expression is observed. Does this perturbation lead to a significant difference in HIST1H3H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Determine whether C8orf22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Determine whether C8orf22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 578,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor CTC-490E21.10 expression. Decide whether this perturbation leads to a significant alteration in CTC-490E21.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor CTC-490E21.10 expression. Decide whether this perturbation leads to a significant alteration in CTC-490E21.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1163,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 22,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Determine whether CCM2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Determine whether CCM2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4743,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ICAM4 expression is observed. Does this perturbation lead to a significant difference in ICAM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ICAM4 expression is observed. Does this perturbation lead to a significant difference in ICAM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3418,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor TPH2 expression. Decide whether this perturbation leads to a significant alteration in TPH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor TPH2 expression. Decide whether this perturbation leads to a significant alteration in TPH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3058,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor GPR157 expression. Decide whether this perturbation leads to a significant alteration in GPR157 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor GPR157 expression. Decide whether this perturbation leads to a significant alteration in GPR157 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2640,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Does this perturbation cause a significant change in TUBB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Does this perturbation cause a significant change in TUBB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AC007246.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AC007246.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ANTXR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ANTXR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of NUCB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of NUCB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4080,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of HIST1H3H. Does perturbing NIT1 lead to a significant change in HIST1H3H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of HIST1H3H. Does perturbing NIT1 lead to a significant change in HIST1H3H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ACSL1 expression is measured. Determine whether ACSL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ACSL1 expression is measured. Determine whether ACSL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of SH3RF2. Does perturbing CKS1B lead to a significant change in SH3RF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of SH3RF2. Does perturbing CKS1B lead to a significant change in SH3RF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of TAS2R9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of TAS2R9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3643,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and LTC4S expression is observed. Does this perturbation lead to a significant difference in LTC4S expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and LTC4S expression is observed. Does this perturbation lead to a significant difference in LTC4S expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4930,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Does this perturbation cause a significant change in CPVL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Does this perturbation cause a significant change in CPVL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-259K5.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-259K5.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-219B4.7. Does perturbing AHR lead to a significant change in RP11-219B4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-219B4.7. Does perturbing AHR lead to a significant change in RP11-219B4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 378,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5923,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of SOCS3. Does perturbing MAPK1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of SOCS3. Does perturbing MAPK1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in AREG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in AREG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3970,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Does this perturbation cause a significant change in ARMCX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Does this perturbation cause a significant change in ARMCX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4480,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2518,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor RP11-286H15.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-286H15.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor RP11-286H15.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-286H15.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3880,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Does this perturbation cause a significant change in KRT79 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Does this perturbation cause a significant change in KRT79 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CIB3. Does this perturbation cause a significant change in CIB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CIB3. Does this perturbation cause a significant change in CIB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1010,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of LINC01003. Does this perturbation cause a significant change in LINC01003 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of LINC01003. Does this perturbation cause a significant change in LINC01003 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Determine whether CCDC136 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Determine whether CCDC136 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2378E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2378E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of RASGRF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of RASGRF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2758,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CTD-3131K8.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-3131K8.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CTD-3131K8.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-3131K8.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Determine whether FAM225B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Determine whether FAM225B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ITGA3. Does perturbing FOXL2 lead to a significant change in ITGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ITGA3. Does perturbing FOXL2 lead to a significant change in ITGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5713,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and RHOXF2BB expression is observed. Does this perturbation lead to a significant difference in RHOXF2BB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and RHOXF2BB expression is observed. Does this perturbation lead to a significant difference in RHOXF2BB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2448,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor AC064834.2 expression. Decide whether this perturbation leads to a significant alteration in AC064834.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor AC064834.2 expression. Decide whether this perturbation leads to a significant alteration in AC064834.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CHP1. Does perturbing TGFBR2 lead to a significant change in CHP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CHP1. Does perturbing TGFBR2 lead to a significant change in CHP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ADGB expression is measured. Determine whether ADGB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ADGB expression is measured. Determine whether ADGB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6143,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CCNL1 expression is observed. Does this perturbation lead to a significant difference in CCNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CCNL1 expression is observed. Does this perturbation lead to a significant difference in CCNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3260,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Does this perturbation cause a significant change in NUMB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Does this perturbation cause a significant change in NUMB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Determine whether ARRDC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Determine whether ARRDC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and S100A3 expression is measured. Determine whether S100A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and S100A3 expression is measured. Determine whether S100A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of WDR88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of WDR88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of PNMT. Does perturbing PLK4 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of PNMT. Does perturbing PLK4 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in AC004051.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in AC004051.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ICAM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ICAM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PCDHGA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PCDHGA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of BTG2. Does perturbing SLC6A9 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of BTG2. Does perturbing SLC6A9 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2738,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ZMYND15 expression. Decide whether this perturbation leads to a significant alteration in ZMYND15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ZMYND15 expression. Decide whether this perturbation leads to a significant alteration in ZMYND15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RP11-308D13.3 expression is measured. Determine whether RP11-308D13.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RP11-308D13.3 expression is measured. Determine whether RP11-308D13.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Determine whether POC1B-GALNT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Determine whether POC1B-GALNT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3430,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of RP11-452C8.1. Does perturbing SGK1 lead to a significant change in RP11-452C8.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of RP11-452C8.1. Does perturbing SGK1 lead to a significant change in RP11-452C8.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MS4A2. Does perturbing LYL1 lead to a significant change in MS4A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MS4A2. Does perturbing LYL1 lead to a significant change in MS4A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of MYB. Does perturbing CNN1 lead to a significant change in MYB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of MYB. Does perturbing CNN1 lead to a significant change in MYB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1330,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of MFSD2A. Does perturbing C3orf72 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of MFSD2A. Does perturbing C3orf72 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2268,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of MT1E. Does this perturbation cause a significant change in MT1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of MT1E. Does this perturbation cause a significant change in MT1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3090,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Does this perturbation cause a significant change in ZNF677 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Does this perturbation cause a significant change in ZNF677 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6040,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Does this perturbation cause a significant change in NPW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Does this perturbation cause a significant change in NPW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Determine whether FZD6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Determine whether FZD6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C8orf22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C8orf22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2203,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and LINC01342 expression is observed. Does this perturbation lead to a significant difference in LINC01342 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and LINC01342 expression is observed. Does this perturbation lead to a significant difference in LINC01342 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ZNF677 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ZNF677 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2590,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of RP11-76E17.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of RP11-76E17.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Determine whether RP11-646I6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Determine whether RP11-646I6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is quantified. Does this perturbation result in a significant change in UCKL1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is quantified. Does this perturbation result in a significant change in UCKL1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4803,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and AC139099.6 expression is measured. Determine whether AC139099.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and AC139099.6 expression is measured. Determine whether AC139099.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4108,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CD37. Does perturbing CLDN6 lead to a significant change in CD37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CD37. Does perturbing CLDN6 lead to a significant change in CD37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PAMR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PAMR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of TRGVA. Does this perturbation cause a significant change in TRGVA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of TRGVA. Does this perturbation cause a significant change in TRGVA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SPANXN5 expression is quantified. Does this perturbation result in a significant change in SPANXN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SPANXN5 expression is quantified. Does this perturbation result in a significant change in SPANXN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of DPYSL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of DPYSL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4808,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 12,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and CLU expression is quantified. Does this perturbation result in a significant change in CLU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and CLU expression is quantified. Does this perturbation result in a significant change in CLU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3928,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor GPR35 expression. Decide whether this perturbation leads to a significant alteration in GPR35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor GPR35 expression. Decide whether this perturbation leads to a significant alteration in GPR35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 498,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 59,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SLC22A25 expression is measured. Determine whether SLC22A25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SLC22A25 expression is measured. Determine whether SLC22A25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and STRA6 expression is quantified. Does this perturbation result in a significant change in STRA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and STRA6 expression is quantified. Does this perturbation result in a significant change in STRA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6093,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of RP11-202A13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of RP11-202A13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1603,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and RPS6KA2 expression is observed. Does this perturbation lead to a significant difference in RPS6KA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and RPS6KA2 expression is observed. Does this perturbation lead to a significant difference in RPS6KA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4963,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Determine whether CTA-384D8.34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Determine whether CTA-384D8.34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA2 expression is quantified. Does this perturbation result in a significant change in ANXA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA2 expression is quantified. Does this perturbation result in a significant change in ANXA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of MYO1F. Does perturbing MIDN lead to a significant change in MYO1F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of MYO1F. Does perturbing MIDN lead to a significant change in MYO1F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of GPR35. Does this perturbation cause a significant change in GPR35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of GPR35. Does this perturbation cause a significant change in GPR35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and AC007556.3 expression is measured. Determine whether AC007556.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and AC007556.3 expression is measured. Determine whether AC007556.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of RP11-180M15.6. Does this perturbation cause a significant change in RP11-180M15.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of RP11-180M15.6. Does this perturbation cause a significant change in RP11-180M15.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1948,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ORAI3 expression. Decide whether this perturbation leads to a significant alteration in ORAI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ORAI3 expression. Decide whether this perturbation leads to a significant alteration in ORAI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ABCA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ABCA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CRAT37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CRAT37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1030,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Does this perturbation cause a significant change in PTRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Does this perturbation cause a significant change in PTRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3803,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and TAC3 expression is observed. Does this perturbation lead to a significant difference in TAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and TAC3 expression is observed. Does this perturbation lead to a significant difference in TAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3623,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of RSPO4. Does this perturbation cause a significant change in RSPO4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of RSPO4. Does this perturbation cause a significant change in RSPO4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of TYROBP. Does perturbing SPI1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of TYROBP. Does perturbing SPI1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-290K4.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-290K4.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5080,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in TFRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in TFRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5098,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor PLEK expression. Decide whether this perturbation leads to a significant alteration in PLEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor PLEK expression. Decide whether this perturbation leads to a significant alteration in PLEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in AMPH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in AMPH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of TMEM35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of TMEM35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of DSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of DSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3258,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor UNC5B expression. Decide whether this perturbation leads to a significant alteration in UNC5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor UNC5B expression. Decide whether this perturbation leads to a significant alteration in UNC5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1680,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Does this perturbation cause a significant change in LMNA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Does this perturbation cause a significant change in LMNA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Determine whether NPW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Determine whether NPW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and RAB5B expression is measured. Determine whether RAB5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and RAB5B expression is measured. Determine whether RAB5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3028,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor MYC expression. Decide whether this perturbation leads to a significant alteration in MYC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor MYC expression. Decide whether this perturbation leads to a significant alteration in MYC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3493,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and TAS2R9 expression is measured. Determine whether TAS2R9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and TAS2R9 expression is measured. Determine whether TAS2R9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3920,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Does this perturbation cause a significant change in GPR35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Does this perturbation cause a significant change in GPR35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3203,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4773,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and INADL expression is quantified. Does this perturbation result in a significant change in INADL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and INADL expression is quantified. Does this perturbation result in a significant change in INADL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Determine whether TPH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Determine whether TPH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CDK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CDK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2778,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ACSL1 expression. Decide whether this perturbation leads to a significant alteration in ACSL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ACSL1 expression. Decide whether this perturbation leads to a significant alteration in ACSL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1450,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CPXM1. Does this perturbation cause a significant change in CPXM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CPXM1. Does this perturbation cause a significant change in CPXM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is quantified. Does this perturbation result in a significant change in RP11-109E24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is quantified. Does this perturbation result in a significant change in RP11-109E24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3620,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-109E24.2. Does perturbing EGR1 lead to a significant change in RP11-109E24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-109E24.2. Does perturbing EGR1 lead to a significant change in RP11-109E24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of BST2. Does perturbing TGFBR2 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of BST2. Does perturbing TGFBR2 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and PPP4R4 expression is quantified. Does this perturbation result in a significant change in PPP4R4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and PPP4R4 expression is quantified. Does this perturbation result in a significant change in PPP4R4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is measured. Determine whether RP11-714G18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is measured. Determine whether RP11-714G18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1993,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SLC2A1-AS1 expression is observed. Does this perturbation lead to a significant difference in SLC2A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SLC2A1-AS1 expression is observed. Does this perturbation lead to a significant difference in SLC2A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in SLC31A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in SLC31A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4420,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Does this perturbation cause a significant change in COL21A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Does this perturbation cause a significant change in COL21A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2538,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SLC2A3 expression. Decide whether this perturbation leads to a significant alteration in SLC2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SLC2A3 expression. Decide whether this perturbation leads to a significant alteration in SLC2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is measured. Determine whether RP11-195B3.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is measured. Determine whether RP11-195B3.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5750,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Does this perturbation cause a significant change in YPEL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Does this perturbation cause a significant change in YPEL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 41,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP11-445O3.3. Does perturbing TSC22D1 lead to a significant change in RP11-445O3.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP11-445O3.3. Does perturbing TSC22D1 lead to a significant change in RP11-445O3.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Determine whether SLC8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Determine whether SLC8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of GIPR. Does this perturbation cause a significant change in GIPR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of GIPR. Does this perturbation cause a significant change in GIPR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3763,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and IL20 expression is observed. Does this perturbation lead to a significant difference in IL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and IL20 expression is observed. Does this perturbation lead to a significant difference in IL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 530,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Does this perturbation cause a significant change in ATP9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Does this perturbation cause a significant change in ATP9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ARHGEF6 expression is quantified. Does this perturbation result in a significant change in ARHGEF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ARHGEF6 expression is quantified. Does this perturbation result in a significant change in ARHGEF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and CCNG2 expression is quantified. Does this perturbation result in a significant change in CCNG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and CCNG2 expression is quantified. Does this perturbation result in a significant change in CCNG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2003,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and REEP6 expression is observed. Does this perturbation lead to a significant difference in REEP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and REEP6 expression is observed. Does this perturbation lead to a significant difference in REEP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3863,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and DNAJB1 expression is observed. Does this perturbation lead to a significant difference in DNAJB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and DNAJB1 expression is observed. Does this perturbation lead to a significant difference in DNAJB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and MMP19 expression is quantified. Does this perturbation result in a significant change in MMP19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and MMP19 expression is quantified. Does this perturbation result in a significant change in MMP19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and EMP3 expression is quantified. Does this perturbation result in a significant change in EMP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and EMP3 expression is quantified. Does this perturbation result in a significant change in EMP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1260,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-328J14.1. Does perturbing IER5L lead to a significant change in RP11-328J14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-328J14.1. Does perturbing IER5L lead to a significant change in RP11-328J14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2360,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and COTL1 expression is measured. Determine whether COTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and COTL1 expression is measured. Determine whether COTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is measured. Determine whether CTD-2311M21.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is measured. Determine whether CTD-2311M21.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in POC1B-GALNT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in POC1B-GALNT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIPK1-AS1. Does this perturbation cause a significant change in HIPK1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIPK1-AS1. Does this perturbation cause a significant change in HIPK1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of AIM1. Does perturbing HOXC13 lead to a significant change in AIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of AIM1. Does perturbing HOXC13 lead to a significant change in AIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CTD-2031P19.5 expression is measured. Determine whether CTD-2031P19.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CTD-2031P19.5 expression is measured. Determine whether CTD-2031P19.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Determine whether RP11-452C8.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Determine whether RP11-452C8.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6063,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and CEBPD expression is observed. Does this perturbation lead to a significant difference in CEBPD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and CEBPD expression is observed. Does this perturbation lead to a significant difference in CEBPD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5188,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor TMEM88 expression. Decide whether this perturbation leads to a significant alteration in TMEM88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor TMEM88 expression. Decide whether this perturbation leads to a significant alteration in TMEM88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in LPAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in LPAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Determine whether CRABP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Determine whether CRABP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of DYNLT3. Does perturbing TP73 lead to a significant change in DYNLT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of DYNLT3. Does perturbing TP73 lead to a significant change in DYNLT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CD59 expression is quantified. Does this perturbation result in a significant change in CD59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CD59 expression is quantified. Does this perturbation result in a significant change in CD59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5958,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RUNX3 expression. Decide whether this perturbation leads to a significant alteration in RUNX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RUNX3 expression. Decide whether this perturbation leads to a significant alteration in RUNX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SLC22A25. Does perturbing FOXO4 lead to a significant change in SLC22A25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SLC22A25. Does perturbing FOXO4 lead to a significant change in SLC22A25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TUBB2B. Does perturbing MEIS1 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TUBB2B. Does perturbing MEIS1 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Determine whether FCGR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Determine whether FCGR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and IGFL2 expression is quantified. Does this perturbation result in a significant change in IGFL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and IGFL2 expression is quantified. Does this perturbation result in a significant change in IGFL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Determine whether IL1RN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Determine whether IL1RN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and AREG expression is quantified. Does this perturbation result in a significant change in AREG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and AREG expression is quantified. Does this perturbation result in a significant change in AREG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and UNC5B expression is measured. Determine whether UNC5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and UNC5B expression is measured. Determine whether UNC5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 343,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of AREG. Does perturbing TBX2 lead to a significant change in AREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of AREG. Does perturbing TBX2 lead to a significant change in AREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and IER3 expression is measured. Determine whether IER3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and IER3 expression is measured. Determine whether IER3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in INHBE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in INHBE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of PRTN3. Does perturbing RREB1 lead to a significant change in PRTN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of PRTN3. Does perturbing RREB1 lead to a significant change in PRTN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2278,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor RP11-537H15.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-537H15.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor RP11-537H15.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-537H15.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3123,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and AIM1 expression is observed. Does this perturbation lead to a significant difference in AIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and AIM1 expression is observed. Does this perturbation lead to a significant difference in AIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of N4BP2L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of N4BP2L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of TPH2. Does perturbing SAMD1 lead to a significant change in TPH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of TPH2. Does perturbing SAMD1 lead to a significant change in TPH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2208,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor LINC01342 expression. Decide whether this perturbation leads to a significant alteration in LINC01342 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor LINC01342 expression. Decide whether this perturbation leads to a significant alteration in LINC01342 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4343,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and HIST1H4H expression is observed. Does this perturbation lead to a significant difference in HIST1H4H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and HIST1H4H expression is observed. Does this perturbation lead to a significant difference in HIST1H4H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of CTA-384D8.34. Does perturbing BAK1 lead to a significant change in CTA-384D8.34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of CTA-384D8.34. Does perturbing BAK1 lead to a significant change in CTA-384D8.34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNDC3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNDC3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5980,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and LTC4S expression is measured. Determine whether LTC4S exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and LTC4S expression is measured. Determine whether LTC4S exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1708,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor SP6 expression. Decide whether this perturbation leads to a significant alteration in SP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor SP6 expression. Decide whether this perturbation leads to a significant alteration in SP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 453,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and LINC01003 expression is observed. Does this perturbation lead to a significant difference in LINC01003 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and LINC01003 expression is observed. Does this perturbation lead to a significant difference in LINC01003 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2148,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCM2L expression. Decide whether this perturbation leads to a significant alteration in CCM2L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCM2L expression. Decide whether this perturbation leads to a significant alteration in CCM2L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ZNF431. Does perturbing CSRNP1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ZNF431. Does perturbing CSRNP1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01358. Does perturbing ZBTB10 lead to a significant change in LINC01358 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01358. Does perturbing ZBTB10 lead to a significant change in LINC01358 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Determine whether MS4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Determine whether MS4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of SLC43A2. Does perturbing MIDN lead to a significant change in SLC43A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of SLC43A2. Does perturbing MIDN lead to a significant change in SLC43A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CACNA1C-AS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CACNA1C-AS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4450,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Does this perturbation cause a significant change in RHOH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Does this perturbation cause a significant change in RHOH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD47. Does this perturbation cause a significant change in CD47 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD47. Does this perturbation cause a significant change in CD47 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and REEP6 expression is measured. Determine whether REEP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and REEP6 expression is measured. Determine whether REEP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5423,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01420 expression is observed. Does this perturbation lead to a significant difference in LINC01420 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01420 expression is observed. Does this perturbation lead to a significant difference in LINC01420 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of TAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of TAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is measured. Determine whether RP4-550H1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is measured. Determine whether RP4-550H1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3610,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in CRABP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in CRABP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C8orf22. Does perturbing RHOXF2BB lead to a significant change in C8orf22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C8orf22. Does perturbing RHOXF2BB lead to a significant change in C8orf22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ARPC3. Does this perturbation cause a significant change in ARPC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ARPC3. Does this perturbation cause a significant change in ARPC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of TNNI3. Does perturbing HES7 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of TNNI3. Does perturbing HES7 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of RP11-91A18.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of RP11-91A18.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is measured. Determine whether RP11-505P4.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is measured. Determine whether RP11-505P4.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3940,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Does this perturbation cause a significant change in MYOZ3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Does this perturbation cause a significant change in MYOZ3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLAUR. Does perturbing CBL lead to a significant change in PLAUR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLAUR. Does perturbing CBL lead to a significant change in PLAUR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in VASH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in VASH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of TRPM2. Does this perturbation cause a significant change in TRPM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of TRPM2. Does this perturbation cause a significant change in TRPM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5663,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and DRC1 expression is observed. Does this perturbation lead to a significant difference in DRC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and DRC1 expression is observed. Does this perturbation lead to a significant difference in DRC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and MMP19 expression is measured. Determine whether MMP19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and MMP19 expression is measured. Determine whether MMP19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-328J14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-328J14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 75,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5570,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of SLC8A1. Does this perturbation cause a significant change in SLC8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of SLC8A1. Does this perturbation cause a significant change in SLC8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 110,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Does this perturbation cause a significant change in KIAA2012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Does this perturbation cause a significant change in KIAA2012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Determine whether RELB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Determine whether RELB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1063,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-510J16.5 expression is observed. Does this perturbation lead to a significant difference in RP11-510J16.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-510J16.5 expression is observed. Does this perturbation lead to a significant difference in RP11-510J16.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1160,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ANXA2R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ANXA2R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2290,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Does this perturbation cause a significant change in AC007246.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Does this perturbation cause a significant change in AC007246.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1310,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Does this perturbation cause a significant change in LINC01562 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Does this perturbation cause a significant change in LINC01562 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in CST9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in CST9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and SPARC expression is quantified. Does this perturbation result in a significant change in SPARC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and SPARC expression is quantified. Does this perturbation result in a significant change in SPARC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4150,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ADGB. Does perturbing JUN lead to a significant change in ADGB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ADGB. Does perturbing JUN lead to a significant change in ADGB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3270,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Does this perturbation cause a significant change in CARMN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Does this perturbation cause a significant change in CARMN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Determine whether TM4SF1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Determine whether TM4SF1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TRIM31 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TRIM31 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Determine whether PROX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Determine whether PROX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-514P8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-514P8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and HCAR2 expression is quantified. Does this perturbation result in a significant change in HCAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and HCAR2 expression is quantified. Does this perturbation result in a significant change in HCAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and CHST15 expression is quantified. Does this perturbation result in a significant change in CHST15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and CHST15 expression is quantified. Does this perturbation result in a significant change in CHST15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4940,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Does this perturbation cause a significant change in LEFTY2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Does this perturbation cause a significant change in LEFTY2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of SEMA3B. Does perturbing CEBPA lead to a significant change in SEMA3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of SEMA3B. Does perturbing CEBPA lead to a significant change in SEMA3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4423,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and COL21A1 expression is observed. Does this perturbation lead to a significant difference in COL21A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and COL21A1 expression is observed. Does this perturbation lead to a significant difference in COL21A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and RSPO4 expression is quantified. Does this perturbation result in a significant change in RSPO4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and RSPO4 expression is quantified. Does this perturbation result in a significant change in RSPO4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 878,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 370,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3890,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Does this perturbation cause a significant change in HMGA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Does this perturbation cause a significant change in HMGA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2860,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Does this perturbation cause a significant change in HOGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Does this perturbation cause a significant change in HOGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1083,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and SERPINF1 expression is observed. Does this perturbation lead to a significant difference in SERPINF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and SERPINF1 expression is observed. Does this perturbation lead to a significant difference in SERPINF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4440,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2140,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Does this perturbation cause a significant change in CCM2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Does this perturbation cause a significant change in CCM2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5640,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ARRDC3 expression is quantified. Does this perturbation result in a significant change in ARRDC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ARRDC3 expression is quantified. Does this perturbation result in a significant change in ARRDC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of NBR1. Does perturbing NCL lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of NBR1. Does perturbing NCL lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of AC004051.2. Does this perturbation cause a significant change in AC004051.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of AC004051.2. Does this perturbation cause a significant change in AC004051.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RP11-83A24.2. Does perturbing GLB1L2 lead to a significant change in RP11-83A24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RP11-83A24.2. Does perturbing GLB1L2 lead to a significant change in RP11-83A24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 99,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and TDRD12 expression is measured. Determine whether TDRD12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and TDRD12 expression is measured. Determine whether TDRD12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 623,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in SLC43A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in SLC43A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of APOL6. Does perturbing COL1A1 lead to a significant change in APOL6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of APOL6. Does perturbing COL1A1 lead to a significant change in APOL6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCM2L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCM2L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 790,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 558,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4758,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of DYNLL1. Does this perturbation cause a significant change in DYNLL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of DYNLL1. Does this perturbation cause a significant change in DYNLL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2620,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Does this perturbation cause a significant change in XK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Does this perturbation cause a significant change in XK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Determine whether RP11-195B3.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Determine whether RP11-195B3.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LRRTM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LRRTM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is measured. Determine whether POC1B-GALNT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is measured. Determine whether POC1B-GALNT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of PGA4. Does perturbing PRDM1 lead to a significant change in PGA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of PGA4. Does perturbing PRDM1 lead to a significant change in PGA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ACTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ACTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Determine whether SP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Determine whether SP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of HBG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of HBG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MS4A3 expression is quantified. Does this perturbation result in a significant change in MS4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MS4A3 expression is quantified. Does this perturbation result in a significant change in MS4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ETS1. Does this perturbation cause a significant change in ETS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ETS1. Does this perturbation cause a significant change in ETS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of SLC38A2. Does perturbing SLC38A2 lead to a significant change in SLC38A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of SLC38A2. Does perturbing SLC38A2 lead to a significant change in SLC38A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1273,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5513,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of TAS1R1. Does this perturbation cause a significant change in TAS1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of TAS1R1. Does this perturbation cause a significant change in TAS1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of CTD-2616J11.16. Does perturbing ZNF318 lead to a significant change in CTD-2616J11.16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of CTD-2616J11.16. Does perturbing ZNF318 lead to a significant change in CTD-2616J11.16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of THBS1. Does perturbing CKS1B lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of THBS1. Does perturbing CKS1B lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of RP11-442O1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of RP11-442O1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4110,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Does this perturbation cause a significant change in RSPO4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Does this perturbation cause a significant change in RSPO4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FAM83A. Does this perturbation cause a significant change in FAM83A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FAM83A. Does this perturbation cause a significant change in FAM83A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLA2G16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLA2G16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and NUDC expression is measured. Determine whether NUDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and NUDC expression is measured. Determine whether NUDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of TFRC. Does this perturbation cause a significant change in TFRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of TFRC. Does this perturbation cause a significant change in TFRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and CTSW expression is quantified. Does this perturbation result in a significant change in CTSW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and CTSW expression is quantified. Does this perturbation result in a significant change in CTSW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of NCKAP1L. Does perturbing HOXB9 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of NCKAP1L. Does perturbing HOXB9 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-52L5.6. Does this perturbation cause a significant change in RP11-52L5.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-52L5.6. Does this perturbation cause a significant change in RP11-52L5.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in MCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in MCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CDC45. Does perturbing CDKN1C lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CDC45. Does perturbing CDKN1C lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and IL20 expression is quantified. Does this perturbation result in a significant change in IL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and IL20 expression is quantified. Does this perturbation result in a significant change in IL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of RP11-505P4.6. Does perturbing RREB1 lead to a significant change in RP11-505P4.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of RP11-505P4.6. Does perturbing RREB1 lead to a significant change in RP11-505P4.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in SSTR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in SSTR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RIT1 expression is quantified. Does this perturbation result in a significant change in RIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RIT1 expression is quantified. Does this perturbation result in a significant change in RIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2648,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor TUBB expression. Decide whether this perturbation leads to a significant alteration in TUBB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor TUBB expression. Decide whether this perturbation leads to a significant alteration in TUBB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of AIF1. Does perturbing ZNF318 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of AIF1. Does perturbing ZNF318 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in FZD6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in FZD6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ARHGDIB. Does perturbing MAP4K5 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ARHGDIB. Does perturbing MAP4K5 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1343,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and CRYAB expression is observed. Does this perturbation lead to a significant difference in CRYAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and CRYAB expression is observed. Does this perturbation lead to a significant difference in CRYAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3673,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of LINC01338. Does this perturbation cause a significant change in LINC01338 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of LINC01338. Does this perturbation cause a significant change in LINC01338 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of RP11-244F12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of RP11-244F12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RP11-285F7.2. Does this perturbation cause a significant change in RP11-285F7.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RP11-285F7.2. Does this perturbation cause a significant change in RP11-285F7.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of UBASH3A. Does perturbing RUNX1T1 lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of UBASH3A. Does perturbing RUNX1T1 lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RNF213. Does perturbing ISL2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RNF213. Does perturbing ISL2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5183,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and TMEM88 expression is observed. Does this perturbation lead to a significant difference in TMEM88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and TMEM88 expression is observed. Does this perturbation lead to a significant difference in TMEM88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 668,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor PTPRS expression. Decide whether this perturbation leads to a significant alteration in PTPRS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor PTPRS expression. Decide whether this perturbation leads to a significant alteration in PTPRS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01420. Does perturbing CDKN1B lead to a significant change in LINC01420 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01420. Does perturbing CDKN1B lead to a significant change in LINC01420 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5440,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Determine whether HOGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Determine whether HOGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of KCNH2. Does perturbing COL1A1 lead to a significant change in KCNH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of KCNH2. Does perturbing COL1A1 lead to a significant change in KCNH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Determine whether TRAPPC3L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Determine whether TRAPPC3L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3010,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4810,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1213,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and AC020571.3 expression is observed. Does this perturbation lead to a significant difference in AC020571.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and AC020571.3 expression is observed. Does this perturbation lead to a significant difference in AC020571.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3008,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3693,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-514P8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-514P8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-514P8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-514P8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and SLC22A11 expression is quantified. Does this perturbation result in a significant change in SLC22A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and SLC22A11 expression is quantified. Does this perturbation result in a significant change in SLC22A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of SPARC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of SPARC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Determine whether COTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Determine whether COTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2543,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in RP11-442O1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in RP11-442O1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ATG2A. Does perturbing PRTG lead to a significant change in ATG2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ATG2A. Does perturbing PRTG lead to a significant change in ATG2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CYP1B1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CYP1B1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Determine whether SCG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Determine whether SCG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Determine whether CEBPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Determine whether CEBPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and IGFL2 expression is measured. Determine whether IGFL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and IGFL2 expression is measured. Determine whether IGFL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Determine whether CKS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Determine whether CKS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 283,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and CRABP2 expression is observed. Does this perturbation lead to a significant difference in CRABP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and CRABP2 expression is observed. Does this perturbation lead to a significant difference in CRABP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of RNF182. Does this perturbation cause a significant change in RNF182 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of RNF182. Does this perturbation cause a significant change in RNF182 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in PRTN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in PRTN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4998,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor MARCKS expression. Decide whether this perturbation leads to a significant alteration in MARCKS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor MARCKS expression. Decide whether this perturbation leads to a significant alteration in MARCKS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA2 expression is measured. Determine whether ANXA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA2 expression is measured. Determine whether ANXA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1530,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Does this perturbation cause a significant change in SLC43A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Does this perturbation cause a significant change in SLC43A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3458,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Determine whether AC064834.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Determine whether AC064834.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HHEX. Does this perturbation cause a significant change in HHEX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HHEX. Does this perturbation cause a significant change in HHEX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Determine whether CACNA1C-AS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Determine whether CACNA1C-AS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4688,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of RP3-525N10.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of RP3-525N10.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5433,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01227 expression is observed. Does this perturbation lead to a significant difference in LINC01227 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01227 expression is observed. Does this perturbation lead to a significant difference in LINC01227 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of PCK1. Does perturbing SLC38A2 lead to a significant change in PCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of PCK1. Does perturbing SLC38A2 lead to a significant change in PCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3668,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of HEMGN. Does perturbing ELMSAN1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of HEMGN. Does perturbing ELMSAN1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Determine whether ORAI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Determine whether ORAI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5090,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Does this perturbation cause a significant change in PLEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Does this perturbation cause a significant change in PLEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 710,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Does this perturbation cause a significant change in SKAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Does this perturbation cause a significant change in SKAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 40,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Does this perturbation cause a significant change in RP11-445O3.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Does this perturbation cause a significant change in RP11-445O3.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2880,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6233,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1930,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of CST9L. Does perturbing FOXA3 lead to a significant change in CST9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of CST9L. Does perturbing FOXA3 lead to a significant change in CST9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of LINC00479. Does perturbing BCORL1 lead to a significant change in LINC00479 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of LINC00479. Does perturbing BCORL1 lead to a significant change in LINC00479 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4860,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3070,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3280,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Does this perturbation cause a significant change in RIMBP3C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Does this perturbation cause a significant change in RIMBP3C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RP11-83A24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RP11-83A24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and FABP3 expression is quantified. Does this perturbation result in a significant change in FABP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and FABP3 expression is quantified. Does this perturbation result in a significant change in FABP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3463,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SPANXN5 expression is observed. Does this perturbation lead to a significant difference in SPANXN5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SPANXN5 expression is observed. Does this perturbation lead to a significant difference in SPANXN5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1338,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of RP11-180M15.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of RP11-180M15.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of EWSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of EWSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RUNX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RUNX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4778,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in RP1-261G23.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in RP1-261G23.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LRRC74B expression is quantified. Does this perturbation result in a significant change in LRRC74B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LRRC74B expression is quantified. Does this perturbation result in a significant change in LRRC74B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MS4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MS4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of NCF4. Does perturbing CBL lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of NCF4. Does perturbing CBL lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of DEK. Does this perturbation cause a significant change in DEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of DEK. Does this perturbation cause a significant change in DEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-328J14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-328J14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2793,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and KRT7 expression is observed. Does this perturbation lead to a significant difference in KRT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and KRT7 expression is observed. Does this perturbation lead to a significant difference in KRT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of GPR157. Does perturbing IKZF3 lead to a significant change in GPR157 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of GPR157. Does perturbing IKZF3 lead to a significant change in GPR157 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of PRKCB. Does perturbing ARRDC3 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of PRKCB. Does perturbing ARRDC3 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Determine whether PLAUR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Determine whether PLAUR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 938,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CYP2C18 expression. Decide whether this perturbation leads to a significant alteration in CYP2C18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CYP2C18 expression. Decide whether this perturbation leads to a significant alteration in CYP2C18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5610,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Does this perturbation cause a significant change in LINC01358 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Does this perturbation cause a significant change in LINC01358 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5730,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Does this perturbation cause a significant change in PCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Does this perturbation cause a significant change in PCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2050,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and RASGRF2 expression is measured. Determine whether RASGRF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and RASGRF2 expression is measured. Determine whether RASGRF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of LGALS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of LGALS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4923,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and BCL2L11 expression is observed. Does this perturbation lead to a significant difference in BCL2L11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and BCL2L11 expression is observed. Does this perturbation lead to a significant difference in BCL2L11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3498,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CTD-2012K14.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CTD-2012K14.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TMEM55A expression is quantified. Does this perturbation result in a significant change in TMEM55A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TMEM55A expression is quantified. Does this perturbation result in a significant change in TMEM55A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3813,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-563J2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-563J2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-563J2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-563J2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of SOX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of SOX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-563J2.3. Does perturbing ARRDC3 lead to a significant change in RP11-563J2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-563J2.3. Does perturbing ARRDC3 lead to a significant change in RP11-563J2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of TMEM35. Does perturbing ZC3HAV1 lead to a significant change in TMEM35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of TMEM35. Does perturbing ZC3HAV1 lead to a significant change in TMEM35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4700,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Does this perturbation cause a significant change in CNN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Does this perturbation cause a significant change in CNN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and MACF1 expression is quantified. Does this perturbation result in a significant change in MACF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and MACF1 expression is quantified. Does this perturbation result in a significant change in MACF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4513,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TPM4 expression is observed. Does this perturbation lead to a significant difference in TPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TPM4 expression is observed. Does this perturbation lead to a significant difference in TPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 248,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of HOGA1. Does this perturbation cause a significant change in HOGA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of HOGA1. Does this perturbation cause a significant change in HOGA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and TRGVA expression is measured. Determine whether TRGVA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and TRGVA expression is measured. Determine whether TRGVA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CREB3L2 expression is quantified. Does this perturbation result in a significant change in CREB3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CREB3L2 expression is quantified. Does this perturbation result in a significant change in CREB3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and TFRC expression is measured. Determine whether TFRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and TFRC expression is measured. Determine whether TFRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of HOGA1. Does perturbing MAPK1 lead to a significant change in HOGA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of HOGA1. Does perturbing MAPK1 lead to a significant change in HOGA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 398,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in RBM5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in RBM5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of RP11-76E17.2. Does this perturbation cause a significant change in RP11-76E17.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of RP11-76E17.2. Does this perturbation cause a significant change in RP11-76E17.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in UNC5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in UNC5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in NPW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in NPW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 79,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of RP11-968A15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of RP11-968A15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2593,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and TAPBP expression is measured. Determine whether TAPBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and TAPBP expression is measured. Determine whether TAPBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2243,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ASIC4 expression is observed. Does this perturbation lead to a significant difference in ASIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ASIC4 expression is observed. Does this perturbation lead to a significant difference in ASIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5953,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RUNX3 expression is observed. Does this perturbation lead to a significant difference in RUNX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RUNX3 expression is observed. Does this perturbation lead to a significant difference in RUNX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of MSX1. Does perturbing SGK1 lead to a significant change in MSX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of MSX1. Does perturbing SGK1 lead to a significant change in MSX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CYP2C18 expression is measured. Determine whether CYP2C18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CYP2C18 expression is measured. Determine whether CYP2C18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4973,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in DSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in DSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5560,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Does this perturbation cause a significant change in MYL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Does this perturbation cause a significant change in MYL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of PCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of PCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-497G19.7. Does this perturbation cause a significant change in RP11-497G19.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-497G19.7. Does this perturbation cause a significant change in RP11-497G19.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 978,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of AC145110.1. Does perturbing HOXB9 lead to a significant change in AC145110.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of AC145110.1. Does perturbing HOXB9 lead to a significant change in AC145110.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6020,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Does this perturbation cause a significant change in IFIT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Does this perturbation cause a significant change in IFIT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ACSL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ACSL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2153,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and NUDC expression is observed. Does this perturbation lead to a significant difference in NUDC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and NUDC expression is observed. Does this perturbation lead to a significant difference in NUDC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Determine whether CIB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Determine whether CIB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of RP11-537H15.3. Does perturbing MAP2K3 lead to a significant change in RP11-537H15.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of RP11-537H15.3. Does perturbing MAP2K3 lead to a significant change in RP11-537H15.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4308,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor SLC22A11 expression. Decide whether this perturbation leads to a significant alteration in SLC22A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor SLC22A11 expression. Decide whether this perturbation leads to a significant alteration in SLC22A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CIB3 expression is quantified. Does this perturbation result in a significant change in CIB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CIB3 expression is quantified. Does this perturbation result in a significant change in CIB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTD-3037G24.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTD-3037G24.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ZIC4 expression is measured. Determine whether ZIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ZIC4 expression is measured. Determine whether ZIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of SLC43A2. Does this perturbation cause a significant change in SLC43A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of SLC43A2. Does this perturbation cause a significant change in SLC43A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Determine whether IL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Determine whether IL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5148,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor RABAC1 expression. Decide whether this perturbation leads to a significant alteration in RABAC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor RABAC1 expression. Decide whether this perturbation leads to a significant alteration in RABAC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of XX-FW83563B9.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of XX-FW83563B9.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-259K5.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-259K5.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and IGHEP2 expression is measured. Determine whether IGHEP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and IGHEP2 expression is measured. Determine whether IGHEP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5508,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 670,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 150,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Does this perturbation cause a significant change in VCX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Does this perturbation cause a significant change in VCX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MBP expression is quantified. Does this perturbation result in a significant change in MBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MBP expression is quantified. Does this perturbation result in a significant change in MBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and TEX30 expression is quantified. Does this perturbation result in a significant change in TEX30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and TEX30 expression is quantified. Does this perturbation result in a significant change in TEX30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is measured. Determine whether RP11-109E24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is measured. Determine whether RP11-109E24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of FABP5. Does perturbing SGK1 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of FABP5. Does perturbing SGK1 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3168,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor PRKAG2-AS1 expression. Decide whether this perturbation leads to a significant alteration in PRKAG2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor PRKAG2-AS1 expression. Decide whether this perturbation leads to a significant alteration in PRKAG2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of AC145110.1. Does this perturbation cause a significant change in AC145110.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of AC145110.1. Does this perturbation cause a significant change in AC145110.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1750,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Does this perturbation cause a significant change in S100A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Does this perturbation cause a significant change in S100A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4720,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Does this perturbation cause a significant change in WDR88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Does this perturbation cause a significant change in WDR88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6028,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor IFIT2 expression. Decide whether this perturbation leads to a significant alteration in IFIT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor IFIT2 expression. Decide whether this perturbation leads to a significant alteration in IFIT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1710,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of AC006262.5. Does perturbing TMSB4X lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of AC006262.5. Does perturbing TMSB4X lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4663,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and RP11-442O1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-442O1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and RP11-442O1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-442O1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3850,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Does this perturbation cause a significant change in CCNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Does this perturbation cause a significant change in CCNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5400,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4690,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is quantified. Does this perturbation result in a significant change in RP6-159A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is quantified. Does this perturbation result in a significant change in RP6-159A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in C1orf228 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in C1orf228 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in SCG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in SCG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 798,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and SLC22A13 expression is measured. Determine whether SLC22A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and SLC22A13 expression is measured. Determine whether SLC22A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and FLJ12825 expression is measured. Determine whether FLJ12825 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and FLJ12825 expression is measured. Determine whether FLJ12825 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3703,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-290K4.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290K4.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-290K4.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290K4.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4833,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and NCALD expression is observed. Does this perturbation lead to a significant difference in NCALD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and NCALD expression is observed. Does this perturbation lead to a significant difference in NCALD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CTD-2031P19.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CTD-2031P19.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5838,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ACP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ACP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is measured. Determine whether RP11-497G19.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is measured. Determine whether RP11-497G19.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3003,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2633,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and AC007193.6 expression is observed. Does this perturbation lead to a significant difference in AC007193.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and AC007193.6 expression is observed. Does this perturbation lead to a significant difference in AC007193.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Determine whether LEFTY1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Determine whether LEFTY1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of AC144568.2. Does perturbing KLF1 lead to a significant change in AC144568.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of AC144568.2. Does perturbing KLF1 lead to a significant change in AC144568.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of CCNB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of CCNB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in SLC8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in SLC8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2228,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP6-159A1.4. Does perturbing MAPK1 lead to a significant change in RP6-159A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP6-159A1.4. Does perturbing MAPK1 lead to a significant change in RP6-159A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of COL18A1-AS1. Does perturbing BAK1 lead to a significant change in COL18A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of COL18A1-AS1. Does perturbing BAK1 lead to a significant change in COL18A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of AVP. Does perturbing IKZF3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of AVP. Does perturbing IKZF3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 820,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Does this perturbation cause a significant change in AC007556.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Does this perturbation cause a significant change in AC007556.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3523,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ATP8A1 expression is observed. Does this perturbation lead to a significant difference in ATP8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ATP8A1 expression is observed. Does this perturbation lead to a significant difference in ATP8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1248,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-259K5.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-259K5.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-259K5.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-259K5.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1220,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Does this perturbation cause a significant change in TFRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Does this perturbation cause a significant change in TFRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of SLC4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of SLC4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of KRT7. Does perturbing FOSB lead to a significant change in KRT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of KRT7. Does perturbing FOSB lead to a significant change in KRT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Determine whether RNF168 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Determine whether RNF168 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3198,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 758,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLA2G1B expression. Decide whether this perturbation leads to a significant alteration in PLA2G1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLA2G1B expression. Decide whether this perturbation leads to a significant alteration in PLA2G1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ATP9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ATP9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in NUCB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in NUCB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5258,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor UCKL1-AS1 expression. Decide whether this perturbation leads to a significant alteration in UCKL1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor UCKL1-AS1 expression. Decide whether this perturbation leads to a significant alteration in UCKL1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCDC148 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCDC148 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and TRAPPC3L expression is measured. Determine whether TRAPPC3L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and TRAPPC3L expression is measured. Determine whether TRAPPC3L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-128B16.3. Does perturbing AHR lead to a significant change in RP11-128B16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-128B16.3. Does perturbing AHR lead to a significant change in RP11-128B16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 350,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-128B16.3 expression is quantified. Does this perturbation result in a significant change in RP11-128B16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-128B16.3 expression is quantified. Does this perturbation result in a significant change in RP11-128B16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and STRC expression is quantified. Does this perturbation result in a significant change in STRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and STRC expression is quantified. Does this perturbation result in a significant change in STRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 80,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ADGB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ADGB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4780,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Does this perturbation cause a significant change in RP11-202A13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Does this perturbation cause a significant change in RP11-202A13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2608,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and PRTN3 expression is measured. Determine whether PRTN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and PRTN3 expression is measured. Determine whether PRTN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of RP11-635N19.1. Does this perturbation cause a significant change in RP11-635N19.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of RP11-635N19.1. Does this perturbation cause a significant change in RP11-635N19.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and SLC7A11 expression is measured. Determine whether SLC7A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and SLC7A11 expression is measured. Determine whether SLC7A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ZMYND15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ZMYND15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and MCC expression is quantified. Does this perturbation result in a significant change in MCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and MCC expression is quantified. Does this perturbation result in a significant change in MCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4908,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RP11-285F7.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-285F7.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RP11-285F7.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-285F7.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of FILIP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of FILIP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2000,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Does this perturbation cause a significant change in REEP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Does this perturbation cause a significant change in REEP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of TMEM154. Does this perturbation cause a significant change in TMEM154 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of TMEM154. Does this perturbation cause a significant change in TMEM154 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and SOX4 expression is measured. Determine whether SOX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and SOX4 expression is measured. Determine whether SOX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3748,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5000,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Does this perturbation cause a significant change in RLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Does this perturbation cause a significant change in RLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ZNF677. Does perturbing HOXB9 lead to a significant change in ZNF677 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ZNF677. Does perturbing HOXB9 lead to a significant change in ZNF677 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of C10orf11. Does perturbing FEV lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of C10orf11. Does perturbing FEV lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5673,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and EGOT expression is observed. Does this perturbation lead to a significant difference in EGOT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and EGOT expression is observed. Does this perturbation lead to a significant difference in EGOT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5503,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of CTSS. Does this perturbation cause a significant change in CTSS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of CTSS. Does this perturbation cause a significant change in CTSS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1400,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of RABGAP1L. Does perturbing ZBTB1 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of RABGAP1L. Does perturbing ZBTB1 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is measured. Determine whether RP11-355B11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is measured. Determine whether RP11-355B11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2653,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and MSRB1 expression is observed. Does this perturbation lead to a significant difference in MSRB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and MSRB1 expression is observed. Does this perturbation lead to a significant difference in MSRB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and FMNL1 expression is quantified. Does this perturbation result in a significant change in FMNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and FMNL1 expression is quantified. Does this perturbation result in a significant change in FMNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3828,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-1017G21.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-1017G21.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-1017G21.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-1017G21.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and SLC4A3 expression is measured. Determine whether SLC4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and SLC4A3 expression is measured. Determine whether SLC4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 368,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor MT1E expression. Decide whether this perturbation leads to a significant alteration in MT1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor MT1E expression. Decide whether this perturbation leads to a significant alteration in MT1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 800,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of CTC-490E21.10. Does this perturbation cause a significant change in CTC-490E21.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of CTC-490E21.10. Does this perturbation cause a significant change in CTC-490E21.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Determine whether RP11-563J2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Determine whether RP11-563J2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 918,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in TNFAIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in TNFAIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AIF1. Does perturbing MAP4K3 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AIF1. Does perturbing MAP4K3 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and KRT7 expression is measured. Determine whether KRT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and KRT7 expression is measured. Determine whether KRT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of XK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of XK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CENPE. Does this perturbation cause a significant change in CENPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CENPE. Does this perturbation cause a significant change in CENPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2953,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Determine whether XX-FW83563B9.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Determine whether XX-FW83563B9.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5038,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor CCDC136 expression. Decide whether this perturbation leads to a significant alteration in CCDC136 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor CCDC136 expression. Decide whether this perturbation leads to a significant alteration in CCDC136 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCDC148 expression is measured. Determine whether CCDC148 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCDC148 expression is measured. Determine whether CCDC148 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ARPC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ARPC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 853,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in FLJ12825 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in FLJ12825 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and DSC1 expression is measured. Determine whether DSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and DSC1 expression is measured. Determine whether DSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4103,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CD37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CD37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3278,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CARMN expression. Decide whether this perturbation leads to a significant alteration in CARMN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CARMN expression. Decide whether this perturbation leads to a significant alteration in CARMN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PRSS57. Does perturbing ZNF318 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PRSS57. Does perturbing ZNF318 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1890,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Does this perturbation cause a significant change in C8orf22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Does this perturbation cause a significant change in C8orf22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LRRC74B. Does this perturbation cause a significant change in LRRC74B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LRRC74B. Does this perturbation cause a significant change in LRRC74B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and TOR3A expression is quantified. Does this perturbation result in a significant change in TOR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and TOR3A expression is quantified. Does this perturbation result in a significant change in TOR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of TRPM2. Does perturbing UBASH3B lead to a significant change in TRPM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of TRPM2. Does perturbing UBASH3B lead to a significant change in TRPM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3613,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PAQR7. Does perturbing ZNF318 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PAQR7. Does perturbing ZNF318 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 95,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in TDRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in TDRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in BCL2L11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in BCL2L11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RHOH. Does this perturbation cause a significant change in RHOH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RHOH. Does this perturbation cause a significant change in RHOH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and COL21A1 expression is quantified. Does this perturbation result in a significant change in COL21A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and COL21A1 expression is quantified. Does this perturbation result in a significant change in COL21A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2500,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Does this perturbation cause a significant change in AREG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Does this perturbation cause a significant change in AREG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and TOX expression is quantified. Does this perturbation result in a significant change in TOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and TOX expression is quantified. Does this perturbation result in a significant change in TOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5563,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and MYL4 expression is observed. Does this perturbation lead to a significant difference in MYL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and MYL4 expression is observed. Does this perturbation lead to a significant difference in MYL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-259K5.1. Does perturbing COL2A1 lead to a significant change in RP11-259K5.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-259K5.1. Does perturbing COL2A1 lead to a significant change in RP11-259K5.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2563,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and PCDHGA3 expression is observed. Does this perturbation lead to a significant difference in PCDHGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and PCDHGA3 expression is observed. Does this perturbation lead to a significant difference in PCDHGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 210,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and LINC01342 expression is measured. Determine whether LINC01342 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and LINC01342 expression is measured. Determine whether LINC01342 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Determine whether SNCG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Determine whether SNCG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HCN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HCN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HHEX. Does perturbing SAMD1 lead to a significant change in HHEX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HHEX. Does perturbing SAMD1 lead to a significant change in HHEX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3113,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and AC145110.1 expression is observed. Does this perturbation lead to a significant difference in AC145110.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and AC145110.1 expression is observed. Does this perturbation lead to a significant difference in AC145110.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of MYB. Does this perturbation cause a significant change in MYB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of MYB. Does this perturbation cause a significant change in MYB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of SLC22A13. Does perturbing MAP2K6 lead to a significant change in SLC22A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of SLC22A13. Does perturbing MAP2K6 lead to a significant change in SLC22A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SLC20A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SLC20A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and HIST1H3H expression is measured. Determine whether HIST1H3H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and HIST1H3H expression is measured. Determine whether HIST1H3H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and TPH2 expression is measured. Determine whether TPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and TPH2 expression is measured. Determine whether TPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and SCG5 expression is quantified. Does this perturbation result in a significant change in SCG5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and SCG5 expression is quantified. Does this perturbation result in a significant change in SCG5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2168,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor SPTAN1 expression. Decide whether this perturbation leads to a significant alteration in SPTAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor SPTAN1 expression. Decide whether this perturbation leads to a significant alteration in SPTAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Determine whether KIAA2012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Determine whether KIAA2012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ATP8B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ATP8B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 968,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of WBP2. Does perturbing CBFA2T3 lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of WBP2. Does perturbing CBFA2T3 lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and PERM1 expression is quantified. Does this perturbation result in a significant change in PERM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and PERM1 expression is quantified. Does this perturbation result in a significant change in PERM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1950,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of SEMA3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of SEMA3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01227. Does this perturbation cause a significant change in LINC01227 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01227. Does this perturbation cause a significant change in LINC01227 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1320,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ACP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ACP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 630,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Does this perturbation cause a significant change in COL18A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Does this perturbation cause a significant change in COL18A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Determine whether CTD-2527I21.14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Determine whether CTD-2527I21.14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and SLC8A1 expression is measured. Determine whether SLC8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and SLC8A1 expression is measured. Determine whether SLC8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3770,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Does this perturbation cause a significant change in RP1-59D14.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Does this perturbation cause a significant change in RP1-59D14.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in RP11-1085N6.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in RP11-1085N6.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1080,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Does this perturbation cause a significant change in SERPINF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Does this perturbation cause a significant change in SERPINF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1850,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Does this perturbation cause a significant change in RP11-714G18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Does this perturbation cause a significant change in RP11-714G18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and FAM225B expression is measured. Determine whether FAM225B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and FAM225B expression is measured. Determine whether FAM225B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3390,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Does this perturbation cause a significant change in CTB-49A3.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Does this perturbation cause a significant change in CTB-49A3.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2008,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor REEP6 expression. Decide whether this perturbation leads to a significant alteration in REEP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor REEP6 expression. Decide whether this perturbation leads to a significant alteration in REEP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CTD-2031P19.5. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CTD-2031P19.5. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-505P4.7. Does this perturbation cause a significant change in RP11-505P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-505P4.7. Does this perturbation cause a significant change in RP11-505P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and LEFTY1 expression is quantified. Does this perturbation result in a significant change in LEFTY1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and LEFTY1 expression is quantified. Does this perturbation result in a significant change in LEFTY1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 390,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Does this perturbation cause a significant change in SH3BGRL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Does this perturbation cause a significant change in SH3BGRL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of N4BP2L2. Does perturbing CEBPA lead to a significant change in N4BP2L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of N4BP2L2. Does perturbing CEBPA lead to a significant change in N4BP2L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in CALY expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in CALY expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Determine whether RP11-355B11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Determine whether RP11-355B11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of KIAA2012. Does this perturbation cause a significant change in KIAA2012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of KIAA2012. Does this perturbation cause a significant change in KIAA2012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of EGOT. Does this perturbation cause a significant change in EGOT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of EGOT. Does this perturbation cause a significant change in EGOT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 17,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of CLU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of CLU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2043,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ATP10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ATP10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Determine whether CARMN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Determine whether CARMN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Determine whether AKAP13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Determine whether AKAP13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of KCNH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of KCNH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5810,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Determine whether RP11-442O1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Determine whether RP11-442O1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1968,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor SIGLEC15 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor SIGLEC15 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PAMR1. Does perturbing CNNM4 lead to a significant change in PAMR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PAMR1. Does perturbing CNNM4 lead to a significant change in PAMR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RHOH expression is quantified. Does this perturbation result in a significant change in RHOH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RHOH expression is quantified. Does this perturbation result in a significant change in RHOH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of RP11-445F12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of RP11-445F12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Determine whether LINC01420 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Determine whether LINC01420 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of TAS1R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of TAS1R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ID3. Does perturbing ELMSAN1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ID3. Does perturbing ELMSAN1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1718,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5262,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3400,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is measured. Determine whether RP6-159A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is measured. Determine whether RP6-159A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SLC20A1. Does this perturbation cause a significant change in SLC20A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SLC20A1. Does this perturbation cause a significant change in SLC20A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1300,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Does this perturbation cause a significant change in PCDHGA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Does this perturbation cause a significant change in PCDHGA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4618,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor PPP4R4 expression. Decide whether this perturbation leads to a significant alteration in PPP4R4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor PPP4R4 expression. Decide whether this perturbation leads to a significant alteration in PPP4R4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 458,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor LINC01003 expression. Decide whether this perturbation leads to a significant alteration in LINC01003 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor LINC01003 expression. Decide whether this perturbation leads to a significant alteration in LINC01003 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1673,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and DEK expression is observed. Does this perturbation lead to a significant difference in DEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and DEK expression is observed. Does this perturbation lead to a significant difference in DEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2733,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ZMYND15 expression is observed. Does this perturbation lead to a significant difference in ZMYND15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ZMYND15 expression is observed. Does this perturbation lead to a significant difference in ZMYND15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in TFAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in TFAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of COTL1. Does perturbing ZBTB25 lead to a significant change in COTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of COTL1. Does perturbing ZBTB25 lead to a significant change in COTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in AC004540.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in AC004540.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and GCM2 expression is measured. Determine whether GCM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and GCM2 expression is measured. Determine whether GCM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Determine whether CTC-490E21.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Determine whether CTC-490E21.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01227 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01227 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3442,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and KCNH2 expression is quantified. Does this perturbation result in a significant change in KCNH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and KCNH2 expression is quantified. Does this perturbation result in a significant change in KCNH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Determine whether PRTN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Determine whether PRTN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1868,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 960,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3443,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and KCNH2 expression is observed. Does this perturbation lead to a significant difference in KCNH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and KCNH2 expression is observed. Does this perturbation lead to a significant difference in KCNH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and MCC expression is measured. Determine whether MCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and MCC expression is measured. Determine whether MCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and AIM1 expression is quantified. Does this perturbation result in a significant change in AIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and AIM1 expression is quantified. Does this perturbation result in a significant change in AIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5688,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM83F expression is quantified. Does this perturbation result in a significant change in FAM83F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM83F expression is quantified. Does this perturbation result in a significant change in FAM83F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 96,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Determine whether TDRD12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Determine whether TDRD12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4823,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2398,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CTD-3126B10.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3126B10.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CTD-3126B10.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3126B10.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of GRAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of GRAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in CLTA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in CLTA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6100,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 483,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Determine whether CHST15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Determine whether CHST15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and GRAP2 expression is measured. Determine whether GRAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and GRAP2 expression is measured. Determine whether GRAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of CTD-2616J11.16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of CTD-2616J11.16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is quantified. Does this perturbation result in a significant change in RP11-968A15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is quantified. Does this perturbation result in a significant change in RP11-968A15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1808,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SAT1 expression. Decide whether this perturbation leads to a significant alteration in SAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SAT1 expression. Decide whether this perturbation leads to a significant alteration in SAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Determine whether SLC2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Determine whether SLC2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RP11-320G24.1. Does perturbing OSR2 lead to a significant change in RP11-320G24.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RP11-320G24.1. Does perturbing OSR2 lead to a significant change in RP11-320G24.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PTRF. Does perturbing SLC4A1 lead to a significant change in PTRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PTRF. Does perturbing SLC4A1 lead to a significant change in PTRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5203,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and TNFAIP2 expression is observed. Does this perturbation lead to a significant difference in TNFAIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and TNFAIP2 expression is observed. Does this perturbation lead to a significant difference in TNFAIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in RELB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in RELB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2188,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor TNFAIP8 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor TNFAIP8 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5020,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2258,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor INADL expression. Decide whether this perturbation leads to a significant alteration in INADL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor INADL expression. Decide whether this perturbation leads to a significant alteration in INADL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of AP1S2. Does perturbing CEBPA lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of AP1S2. Does perturbing CEBPA lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 20,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2728,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of HEATR9. Does this perturbation cause a significant change in HEATR9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of HEATR9. Does this perturbation cause a significant change in HEATR9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of RP11-91A18.4. Does this perturbation cause a significant change in RP11-91A18.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of RP11-91A18.4. Does this perturbation cause a significant change in RP11-91A18.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ST3GAL5 expression is measured. Determine whether ST3GAL5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ST3GAL5 expression is measured. Determine whether ST3GAL5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP6-159A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP6-159A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of RP11-369K17.1. Does this perturbation cause a significant change in RP11-369K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of RP11-369K17.1. Does this perturbation cause a significant change in RP11-369K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of RETN. Does perturbing PTPN1 lead to a significant change in RETN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of RETN. Does perturbing PTPN1 lead to a significant change in RETN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 91,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of TDRD12. Does perturbing MAML2 lead to a significant change in TDRD12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of TDRD12. Does perturbing MAML2 lead to a significant change in TDRD12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5548,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ADGB expression. Decide whether this perturbation leads to a significant alteration in ADGB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ADGB expression. Decide whether this perturbation leads to a significant alteration in ADGB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CD59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CD59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AC006262.5. Does perturbing SLC38A2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AC006262.5. Does perturbing SLC38A2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1730,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Does this perturbation cause a significant change in RP11-195C7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Does this perturbation cause a significant change in RP11-195C7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of SPTAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of SPTAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and CCNJL expression is quantified. Does this perturbation result in a significant change in CCNJL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and CCNJL expression is quantified. Does this perturbation result in a significant change in CCNJL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and HSD17B4 expression is quantified. Does this perturbation result in a significant change in HSD17B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and HSD17B4 expression is quantified. Does this perturbation result in a significant change in HSD17B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2293,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AC007246.3 expression is observed. Does this perturbation lead to a significant difference in AC007246.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AC007246.3 expression is observed. Does this perturbation lead to a significant difference in AC007246.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of HOGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of HOGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Determine whether FAM83A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Determine whether FAM83A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4208,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of STAC3. Does perturbing ELMSAN1 lead to a significant change in STAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of STAC3. Does perturbing ELMSAN1 lead to a significant change in STAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of PNMT. Does perturbing BCORL1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of PNMT. Does perturbing BCORL1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 53,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is quantified. Does this perturbation result in a significant change in SIGLEC15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is quantified. Does this perturbation result in a significant change in SIGLEC15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RP11-320G24.1. Does this perturbation cause a significant change in RP11-320G24.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RP11-320G24.1. Does this perturbation cause a significant change in RP11-320G24.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2658,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor MSRB1 expression. Decide whether this perturbation leads to a significant alteration in MSRB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor MSRB1 expression. Decide whether this perturbation leads to a significant alteration in MSRB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of TYROBP. Does perturbing ETS2 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of TYROBP. Does perturbing ETS2 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3263,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and NUMB expression is observed. Does this perturbation lead to a significant difference in NUMB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and NUMB expression is observed. Does this perturbation lead to a significant difference in NUMB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and CPVL expression is quantified. Does this perturbation result in a significant change in CPVL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and CPVL expression is quantified. Does this perturbation result in a significant change in CPVL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of AC006262.5. Does perturbing KIF2C lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of AC006262.5. Does perturbing KIF2C lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Determine whether CPVL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Determine whether CPVL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of CLTA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of CLTA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and C19orf38 expression is measured. Determine whether C19orf38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and C19orf38 expression is measured. Determine whether C19orf38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Determine whether ANXA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Determine whether ANXA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of SLC22A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of SLC22A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of RAB5B. Does this perturbation cause a significant change in RAB5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of RAB5B. Does this perturbation cause a significant change in RAB5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is measured. Determine whether CTD-2012K14.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is measured. Determine whether CTD-2012K14.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of HBG1. Does perturbing CDKN1B lead to a significant change in HBG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of HBG1. Does perturbing CDKN1B lead to a significant change in HBG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1963,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and SIGLEC15 expression is observed. Does this perturbation lead to a significant difference in SIGLEC15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and SIGLEC15 expression is observed. Does this perturbation lead to a significant difference in SIGLEC15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of RP1-261G23.7. Does this perturbation cause a significant change in RP1-261G23.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of RP1-261G23.7. Does this perturbation cause a significant change in RP1-261G23.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Determine whether KRT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Determine whether KRT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of INADL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of INADL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5823,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ATP10D expression is measured. Determine whether ATP10D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ATP10D expression is measured. Determine whether ATP10D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4573,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 640,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Does this perturbation cause a significant change in CTA-384D8.34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Does this perturbation cause a significant change in CTA-384D8.34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ARRDC3. Does perturbing DUSP9 lead to a significant change in ARRDC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ARRDC3. Does perturbing DUSP9 lead to a significant change in ARRDC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of IFIT2. Does perturbing PRDM1 lead to a significant change in IFIT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of IFIT2. Does perturbing PRDM1 lead to a significant change in IFIT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ZNF610 expression is measured. Determine whether ZNF610 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ZNF610 expression is measured. Determine whether ZNF610 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5863,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and VMP1 expression is observed. Does this perturbation lead to a significant difference in VMP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and VMP1 expression is observed. Does this perturbation lead to a significant difference in VMP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CTD-2311M21.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CTD-2311M21.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Determine whether ZNF677 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Determine whether ZNF677 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is measured. Determine whether KCNQ1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is measured. Determine whether KCNQ1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3120,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Does this perturbation cause a significant change in AIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Does this perturbation cause a significant change in AIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5462,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CHP1 expression is quantified. Does this perturbation result in a significant change in CHP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CHP1 expression is quantified. Does this perturbation result in a significant change in CHP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in TEX30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in TEX30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and AREG expression is measured. Determine whether AREG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and AREG expression is measured. Determine whether AREG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in MYB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in MYB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MS4A3 expression is measured. Determine whether MS4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MS4A3 expression is measured. Determine whether MS4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5058,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor COL1A1 expression. Decide whether this perturbation leads to a significant alteration in COL1A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor COL1A1 expression. Decide whether this perturbation leads to a significant alteration in COL1A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3178,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor SSTR3 expression. Decide whether this perturbation leads to a significant alteration in SSTR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor SSTR3 expression. Decide whether this perturbation leads to a significant alteration in SSTR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1503,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and BMP2K expression is observed. Does this perturbation lead to a significant difference in BMP2K expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and BMP2K expression is observed. Does this perturbation lead to a significant difference in BMP2K expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 403,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CTD-2311M21.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2311M21.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CTD-2311M21.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2311M21.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and SPTAN1 expression is quantified. Does this perturbation result in a significant change in SPTAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and SPTAN1 expression is quantified. Does this perturbation result in a significant change in SPTAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2513,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and RP11-286H15.1 expression is observed. Does this perturbation lead to a significant difference in RP11-286H15.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and RP11-286H15.1 expression is observed. Does this perturbation lead to a significant difference in RP11-286H15.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 818,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor HOXB6 expression. Decide whether this perturbation leads to a significant alteration in HOXB6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor HOXB6 expression. Decide whether this perturbation leads to a significant alteration in HOXB6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLA2G1B. Does perturbing CBL lead to a significant change in PLA2G1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLA2G1B. Does perturbing CBL lead to a significant change in PLA2G1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is measured. Determine whether CTA-384D8.34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is measured. Determine whether CTA-384D8.34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-52L5.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-52L5.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Determine whether RIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Determine whether RIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of MKNK2. Does perturbing CBFA2T3 lead to a significant change in MKNK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of MKNK2. Does perturbing CBFA2T3 lead to a significant change in MKNK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1333,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Determine whether PERM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Determine whether PERM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is quantified. Does this perturbation result in a significant change in CTD-3131K8.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is quantified. Does this perturbation result in a significant change in CTD-3131K8.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and LBH expression is quantified. Does this perturbation result in a significant change in LBH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and LBH expression is quantified. Does this perturbation result in a significant change in LBH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2748,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of SSTR3. Does perturbing HOXC13 lead to a significant change in SSTR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of SSTR3. Does perturbing HOXC13 lead to a significant change in SSTR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-52L5.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-52L5.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 500,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3533,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and C1orf162 expression is observed. Does this perturbation lead to a significant difference in C1orf162 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and C1orf162 expression is observed. Does this perturbation lead to a significant difference in C1orf162 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of CCNB2. Does perturbing KMT2A lead to a significant change in CCNB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of CCNB2. Does perturbing KMT2A lead to a significant change in CCNB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and AK8 expression is quantified. Does this perturbation result in a significant change in AK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and AK8 expression is quantified. Does this perturbation result in a significant change in AK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4178,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ABCA6 expression. Decide whether this perturbation leads to a significant alteration in ABCA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ABCA6 expression. Decide whether this perturbation leads to a significant alteration in ABCA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and PTPRS expression is measured. Determine whether PTPRS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and PTPRS expression is measured. Determine whether PTPRS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 108,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor PSMB8 expression. Decide whether this perturbation leads to a significant alteration in PSMB8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor PSMB8 expression. Decide whether this perturbation leads to a significant alteration in PSMB8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5960,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Does this perturbation cause a significant change in RGPD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Does this perturbation cause a significant change in RGPD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of CSF3R. Does perturbing ZBTB10 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of CSF3R. Does perturbing ZBTB10 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Determine whether ADD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Determine whether ADD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1180,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01227. Does perturbing CDKN1B lead to a significant change in LINC01227 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01227. Does perturbing CDKN1B lead to a significant change in LINC01227 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CCNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CCNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and MOGAT2 expression is measured. Determine whether MOGAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and MOGAT2 expression is measured. Determine whether MOGAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1980,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Does this perturbation cause a significant change in SNCG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Does this perturbation cause a significant change in SNCG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5190,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Does this perturbation cause a significant change in HCAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Does this perturbation cause a significant change in HCAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Determine whether CTSW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Determine whether CTSW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is quantified. Does this perturbation result in a significant change in RP11-244F12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is quantified. Does this perturbation result in a significant change in RP11-244F12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in MARCKS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in MARCKS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3878,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ABCA6 expression is quantified. Does this perturbation result in a significant change in ABCA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ABCA6 expression is quantified. Does this perturbation result in a significant change in ABCA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and C1orf228 expression is measured. Determine whether C1orf228 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and C1orf228 expression is measured. Determine whether C1orf228 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5233,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and FAM225B expression is observed. Does this perturbation lead to a significant difference in FAM225B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and FAM225B expression is observed. Does this perturbation lead to a significant difference in FAM225B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of LEFTY2. Does this perturbation cause a significant change in LEFTY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of LEFTY2. Does this perturbation cause a significant change in LEFTY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and AC007193.6 expression is measured. Determine whether AC007193.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and AC007193.6 expression is measured. Determine whether AC007193.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4003,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and SLC22A13 expression is observed. Does this perturbation lead to a significant difference in SLC22A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and SLC22A13 expression is observed. Does this perturbation lead to a significant difference in SLC22A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 588,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ETS1 expression. Decide whether this perturbation leads to a significant alteration in ETS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ETS1 expression. Decide whether this perturbation leads to a significant alteration in ETS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PPFIA4. Does perturbing ATL1 lead to a significant change in PPFIA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PPFIA4. Does perturbing ATL1 lead to a significant change in PPFIA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of REEP6. Does perturbing S1PR2 lead to a significant change in REEP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of REEP6. Does perturbing S1PR2 lead to a significant change in REEP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 488,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ABCB11. Does this perturbation cause a significant change in ABCB11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ABCB11. Does this perturbation cause a significant change in ABCB11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of S100A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of S100A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ALAS2. Does perturbing MAP4K3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ALAS2. Does perturbing MAP4K3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 548,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3953,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and RNF182 expression is observed. Does this perturbation lead to a significant difference in RNF182 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and RNF182 expression is observed. Does this perturbation lead to a significant difference in RNF182 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of MTURN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of MTURN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 31,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of PDE1B. Does perturbing TSC22D1 lead to a significant change in PDE1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of PDE1B. Does perturbing TSC22D1 lead to a significant change in PDE1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ETS1 expression is quantified. Does this perturbation result in a significant change in ETS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ETS1 expression is quantified. Does this perturbation result in a significant change in ETS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of MFSD2A. Does perturbing HK2 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of MFSD2A. Does perturbing HK2 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5193,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and HCAR2 expression is observed. Does this perturbation lead to a significant difference in HCAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and HCAR2 expression is observed. Does this perturbation lead to a significant difference in HCAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is quantified. Does this perturbation result in a significant change in POC1B-GALNT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is quantified. Does this perturbation result in a significant change in POC1B-GALNT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Determine whether IER3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Determine whether IER3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in RP11-362K14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in RP11-362K14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 593,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and AC144568.2 expression is observed. Does this perturbation lead to a significant difference in AC144568.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and AC144568.2 expression is observed. Does this perturbation lead to a significant difference in AC144568.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PHLDA2. Does perturbing SLC4A1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PHLDA2. Does perturbing SLC4A1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1763,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ST3GAL5 expression is observed. Does this perturbation lead to a significant difference in ST3GAL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ST3GAL5 expression is observed. Does this perturbation lead to a significant difference in ST3GAL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 523,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RP11-83A24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-83A24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RP11-83A24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-83A24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3580,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Does this perturbation cause a significant change in IGHEP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Does this perturbation cause a significant change in IGHEP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 223,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and DDX58 expression is observed. Does this perturbation lead to a significant difference in DDX58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and DDX58 expression is observed. Does this perturbation lead to a significant difference in DDX58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5753,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and YPEL3 expression is observed. Does this perturbation lead to a significant difference in YPEL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and YPEL3 expression is observed. Does this perturbation lead to a significant difference in YPEL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 51,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of TRIM22. Does perturbing TSC22D1 lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of TRIM22. Does perturbing TSC22D1 lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RP11-320G24.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RP11-320G24.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1120,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Does this perturbation cause a significant change in CTC-492K19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Does this perturbation cause a significant change in CTC-492K19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3518,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of CISH. Does perturbing PRTG lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of CISH. Does perturbing PRTG lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1108,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor PRTN3 expression. Decide whether this perturbation leads to a significant alteration in PRTN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor PRTN3 expression. Decide whether this perturbation leads to a significant alteration in PRTN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 29,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Determine whether TFAP2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Determine whether TFAP2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3158,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5733,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and PCK1 expression is observed. Does this perturbation lead to a significant difference in PCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and PCK1 expression is observed. Does this perturbation lead to a significant difference in PCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of SPANXD. Does perturbing KIAA1804 lead to a significant change in SPANXD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of SPANXD. Does perturbing KIAA1804 lead to a significant change in SPANXD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1583,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in MYLIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in MYLIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4218,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of GRN. Does perturbing HOXA13 lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of GRN. Does perturbing HOXA13 lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of IGHEP2. Does this perturbation cause a significant change in IGHEP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of IGHEP2. Does this perturbation cause a significant change in IGHEP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6188,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Determine whether C1orf162 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Determine whether C1orf162 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of NUMB. Does perturbing CLDN6 lead to a significant change in NUMB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of NUMB. Does perturbing CLDN6 lead to a significant change in NUMB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in SLC22A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in SLC22A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of C1orf141. Does perturbing MAP4K3 lead to a significant change in C1orf141 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of C1orf141. Does perturbing MAP4K3 lead to a significant change in C1orf141 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4893,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and SLC7A11 expression is observed. Does this perturbation lead to a significant difference in SLC7A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and SLC7A11 expression is observed. Does this perturbation lead to a significant difference in SLC7A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3303,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RCSD1. Does perturbing SLC6A9 lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RCSD1. Does perturbing SLC6A9 lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5308,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PPFIA4 expression. Decide whether this perturbation leads to a significant alteration in PPFIA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PPFIA4 expression. Decide whether this perturbation leads to a significant alteration in PPFIA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Determine whether MME shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Determine whether MME shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2200,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Does this perturbation cause a significant change in LINC01342 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Does this perturbation cause a significant change in LINC01342 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Determine whether CTD-2311M21.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Determine whether CTD-2311M21.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ARHGEF6. Does perturbing CNN1 lead to a significant change in ARHGEF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ARHGEF6. Does perturbing CNN1 lead to a significant change in ARHGEF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2930,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Does this perturbation cause a significant change in ARL6IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Does this perturbation cause a significant change in ARL6IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RUNX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RUNX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ACSL1. Does perturbing FOSB lead to a significant change in ACSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ACSL1. Does perturbing FOSB lead to a significant change in ACSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of RP11-537H15.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of RP11-537H15.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of DEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of DEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is quantified. Does this perturbation result in a significant change in RP4-565E6.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is quantified. Does this perturbation result in a significant change in RP4-565E6.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of HIST1H4H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of HIST1H4H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2663,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM118A expression is observed. Does this perturbation lead to a significant difference in FAM118A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM118A expression is observed. Does this perturbation lead to a significant difference in FAM118A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 193,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5443,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of FCGR3A. Does this perturbation cause a significant change in FCGR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of FCGR3A. Does this perturbation cause a significant change in FCGR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4658,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LRRC74B expression. Decide whether this perturbation leads to a significant alteration in LRRC74B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LRRC74B expression. Decide whether this perturbation leads to a significant alteration in LRRC74B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of CTD-2616J11.16. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of CTD-2616J11.16. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of AFMID. Does perturbing IRF1 lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of AFMID. Does perturbing IRF1 lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4518,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TPM4 expression. Decide whether this perturbation leads to a significant alteration in TPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TPM4 expression. Decide whether this perturbation leads to a significant alteration in TPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and MYB expression is measured. Determine whether MYB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and MYB expression is measured. Determine whether MYB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Determine whether KRT79 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Determine whether KRT79 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 750,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Does this perturbation cause a significant change in PLA2G1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Does this perturbation cause a significant change in PLA2G1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3983,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and AKAP13 expression is observed. Does this perturbation lead to a significant difference in AKAP13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and AKAP13 expression is observed. Does this perturbation lead to a significant difference in AKAP13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Determine whether CCNG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Determine whether CCNG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6013,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and AMPH expression is observed. Does this perturbation lead to a significant difference in AMPH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and AMPH expression is observed. Does this perturbation lead to a significant difference in AMPH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 63,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3238,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor SH3RF2 expression. Decide whether this perturbation leads to a significant alteration in SH3RF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor SH3RF2 expression. Decide whether this perturbation leads to a significant alteration in SH3RF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Determine whether RP4-550H1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Determine whether RP4-550H1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 733,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLAUR expression is observed. Does this perturbation lead to a significant difference in PLAUR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLAUR expression is observed. Does this perturbation lead to a significant difference in PLAUR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and CLTA expression is quantified. Does this perturbation result in a significant change in CLTA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and CLTA expression is quantified. Does this perturbation result in a significant change in CLTA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 518,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ZNF85 expression. Decide whether this perturbation leads to a significant alteration in ZNF85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ZNF85 expression. Decide whether this perturbation leads to a significant alteration in ZNF85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CHP1 expression is measured. Determine whether CHP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CHP1 expression is measured. Determine whether CHP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD9. Does perturbing BPGM lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD9. Does perturbing BPGM lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and HIST1H4H expression is measured. Determine whether HIST1H4H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and HIST1H4H expression is measured. Determine whether HIST1H4H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 103,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and PSMB8 expression is observed. Does this perturbation lead to a significant difference in PSMB8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and PSMB8 expression is observed. Does this perturbation lead to a significant difference in PSMB8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2280,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ABCB11. Does perturbing CBFA2T3 lead to a significant change in ABCB11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ABCB11. Does perturbing CBFA2T3 lead to a significant change in ABCB11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 810,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Does this perturbation cause a significant change in HOXB6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Does this perturbation cause a significant change in HOXB6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CREB3L2. Does perturbing PRDM1 lead to a significant change in CREB3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CREB3L2. Does perturbing PRDM1 lead to a significant change in CREB3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of CTSW. Does this perturbation cause a significant change in CTSW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of CTSW. Does this perturbation cause a significant change in CTSW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6208,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-52L5.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-52L5.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-52L5.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-52L5.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 410,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Does this perturbation cause a significant change in LINC00479 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Does this perturbation cause a significant change in LINC00479 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of S100A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of S100A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ICAM4. Does this perturbation cause a significant change in ICAM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ICAM4. Does this perturbation cause a significant change in ICAM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of NKG7. Does perturbing PTPN12 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of NKG7. Does perturbing PTPN12 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in RP11-195B3.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in RP11-195B3.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5978,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor HMOX1 expression. Decide whether this perturbation leads to a significant alteration in HMOX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor HMOX1 expression. Decide whether this perturbation leads to a significant alteration in HMOX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-567N4.3. Does perturbing AHR lead to a significant change in RP11-567N4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-567N4.3. Does perturbing AHR lead to a significant change in RP11-567N4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of KRT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of KRT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3858,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CCNB1 expression. Decide whether this perturbation leads to a significant alteration in CCNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CCNB1 expression. Decide whether this perturbation leads to a significant alteration in CCNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RP4-550H1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RP4-550H1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 7,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 943,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and MMP19 expression is observed. Does this perturbation lead to a significant difference in MMP19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and MMP19 expression is observed. Does this perturbation lead to a significant difference in MMP19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLAUR expression is measured. Determine whether PLAUR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLAUR expression is measured. Determine whether PLAUR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Determine whether TMEM35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Determine whether TMEM35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4460,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of MFGE8. Does perturbing TBX2 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of MFGE8. Does perturbing TBX2 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Determine whether AC078941.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Determine whether AC078941.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and PKIG expression is quantified. Does this perturbation result in a significant change in PKIG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and PKIG expression is quantified. Does this perturbation result in a significant change in PKIG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ACTB. Does this perturbation cause a significant change in ACTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ACTB. Does this perturbation cause a significant change in ACTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Determine whether MCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Determine whether MCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4668,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor RP11-442O1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-442O1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor RP11-442O1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-442O1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3433,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TM6SF2. Does perturbing TMSB4X lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TM6SF2. Does perturbing TMSB4X lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Determine whether ATP8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Determine whether ATP8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1178,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor RP11-355B11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-355B11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor RP11-355B11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-355B11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RHOH expression is measured. Determine whether RHOH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RHOH expression is measured. Determine whether RHOH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is measured. Determine whether RP11-968A15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is measured. Determine whether RP11-968A15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1653,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is measured. Determine whether CYP1B1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is measured. Determine whether CYP1B1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 270,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Does this perturbation cause a significant change in STAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Does this perturbation cause a significant change in STAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4458,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RHOH expression. Decide whether this perturbation leads to a significant alteration in RHOH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RHOH expression. Decide whether this perturbation leads to a significant alteration in RHOH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of SLC22A11. Does perturbing HNF4A lead to a significant change in SLC22A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of SLC22A11. Does perturbing HNF4A lead to a significant change in SLC22A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 71,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ID1. Does perturbing MAML2 lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ID1. Does perturbing MAML2 lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Determine whether VCX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Determine whether VCX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of S100A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of S100A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in CEBPD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in CEBPD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1978,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor POC1B-GALNT4 expression. Decide whether this perturbation leads to a significant alteration in POC1B-GALNT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor POC1B-GALNT4 expression. Decide whether this perturbation leads to a significant alteration in POC1B-GALNT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ZNF677 expression is quantified. Does this perturbation result in a significant change in ZNF677 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ZNF677 expression is quantified. Does this perturbation result in a significant change in ZNF677 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-646I6.6. Does perturbing SLC4A1 lead to a significant change in RP11-646I6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-646I6.6. Does perturbing SLC4A1 lead to a significant change in RP11-646I6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Determine whether LINC00479 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Determine whether LINC00479 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5413,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and SLC31A2 expression is observed. Does this perturbation lead to a significant difference in SLC31A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and SLC31A2 expression is observed. Does this perturbation lead to a significant difference in SLC31A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4508,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and MAOB expression is measured. Determine whether MAOB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and MAOB expression is measured. Determine whether MAOB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of TAC3. Does this perturbation cause a significant change in TAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of TAC3. Does this perturbation cause a significant change in TAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and MYB expression is quantified. Does this perturbation result in a significant change in MYB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and MYB expression is quantified. Does this perturbation result in a significant change in MYB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5710,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Does this perturbation cause a significant change in RHOXF2BB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Does this perturbation cause a significant change in RHOXF2BB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ARHGDIB. Does perturbing SGK1 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ARHGDIB. Does perturbing SGK1 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3550,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in RP11-505P4.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in RP11-505P4.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in AC139099.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in AC139099.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of LINC01338. Does perturbing OSR2 lead to a significant change in LINC01338 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of LINC01338. Does perturbing OSR2 lead to a significant change in LINC01338 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of CHST15. Does this perturbation cause a significant change in CHST15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of CHST15. Does this perturbation cause a significant change in CHST15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PPFIA4 expression is measured. Determine whether PPFIA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PPFIA4 expression is measured. Determine whether PPFIA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2070,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Does this perturbation cause a significant change in CKS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Does this perturbation cause a significant change in CKS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 113,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and KIAA2012 expression is observed. Does this perturbation lead to a significant difference in KIAA2012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and KIAA2012 expression is observed. Does this perturbation lead to a significant difference in KIAA2012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of AC020571.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of AC020571.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TUBA1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TUBA1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2988,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1416,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4350,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Does this perturbation cause a significant change in SLCO6A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Does this perturbation cause a significant change in SLCO6A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and AC144568.2 expression is quantified. Does this perturbation result in a significant change in AC144568.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and AC144568.2 expression is quantified. Does this perturbation result in a significant change in AC144568.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Determine whether MYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Determine whether MYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3358,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor VASH1 expression. Decide whether this perturbation leads to a significant alteration in VASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor VASH1 expression. Decide whether this perturbation leads to a significant alteration in VASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4028,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 170,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Does this perturbation cause a significant change in FLJ12825 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Does this perturbation cause a significant change in FLJ12825 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of AC078941.1. Does this perturbation cause a significant change in AC078941.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of AC078941.1. Does this perturbation cause a significant change in AC078941.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of LRRC36. Does this perturbation cause a significant change in LRRC36 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of LRRC36. Does this perturbation cause a significant change in LRRC36 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of XK. Does perturbing PTPN12 lead to a significant change in XK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of XK. Does perturbing PTPN12 lead to a significant change in XK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of MCC. Does perturbing FOXF1 lead to a significant change in MCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of MCC. Does perturbing FOXF1 lead to a significant change in MCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and AC064834.2 expression is measured. Determine whether AC064834.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and AC064834.2 expression is measured. Determine whether AC064834.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of VMP1. Does this perturbation cause a significant change in VMP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of VMP1. Does this perturbation cause a significant change in VMP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2940,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SPANXN5. Does perturbing COL1A1 lead to a significant change in SPANXN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SPANXN5. Does perturbing COL1A1 lead to a significant change in SPANXN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3743,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is quantified. Does this perturbation result in a significant change in CTD-2311M21.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is quantified. Does this perturbation result in a significant change in CTD-2311M21.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Determine whether RP11-52L5.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Determine whether RP11-52L5.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 48,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP11-445O3.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445O3.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP11-445O3.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445O3.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of TTC9B. Does perturbing ISL2 lead to a significant change in TTC9B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of TTC9B. Does perturbing ISL2 lead to a significant change in TTC9B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2253,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and INADL expression is observed. Does this perturbation lead to a significant difference in INADL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and INADL expression is observed. Does this perturbation lead to a significant difference in INADL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of RP4-565E6.1. Does perturbing ELMSAN1 lead to a significant change in RP4-565E6.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of RP4-565E6.1. Does perturbing ELMSAN1 lead to a significant change in RP4-565E6.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and PERM1 expression is measured. Determine whether PERM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and PERM1 expression is measured. Determine whether PERM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in AK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in AK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1383,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1123,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTC-492K19.4 expression is observed. Does this perturbation lead to a significant difference in CTC-492K19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTC-492K19.4 expression is observed. Does this perturbation lead to a significant difference in CTC-492K19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and CRYAB expression is quantified. Does this perturbation result in a significant change in CRYAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and CRYAB expression is quantified. Does this perturbation result in a significant change in CRYAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and PHACTR1 expression is measured. Determine whether PHACTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and PHACTR1 expression is measured. Determine whether PHACTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in KIAA2012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in KIAA2012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2438,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ZNF610 expression. Decide whether this perturbation leads to a significant alteration in ZNF610 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ZNF610 expression. Decide whether this perturbation leads to a significant alteration in ZNF610 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3868,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor DNAJB1 expression. Decide whether this perturbation leads to a significant alteration in DNAJB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor DNAJB1 expression. Decide whether this perturbation leads to a significant alteration in DNAJB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Determine whether SOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Determine whether SOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2263,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and FILIP1L expression is observed. Does this perturbation lead to a significant difference in FILIP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and FILIP1L expression is observed. Does this perturbation lead to a significant difference in FILIP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and RIMBP3C expression is quantified. Does this perturbation result in a significant change in RIMBP3C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and RIMBP3C expression is quantified. Does this perturbation result in a significant change in RIMBP3C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of TSC22D4. Does perturbing DUSP9 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of TSC22D4. Does perturbing DUSP9 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1728,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of DYNLL1. Does perturbing FOSB lead to a significant change in DYNLL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of DYNLL1. Does perturbing FOSB lead to a significant change in DYNLL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5583,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ANTXR2 expression is observed. Does this perturbation lead to a significant difference in ANTXR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ANTXR2 expression is observed. Does this perturbation lead to a significant difference in ANTXR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of COLGALT2. Does perturbing FOXL2 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of COLGALT2. Does perturbing FOXL2 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LINC01562 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LINC01562 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and GPR157 expression is measured. Determine whether GPR157 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and GPR157 expression is measured. Determine whether GPR157 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Determine whether CHP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Determine whether CHP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of LEFTY1. Does perturbing HOXA13 lead to a significant change in LEFTY1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of LEFTY1. Does perturbing HOXA13 lead to a significant change in LEFTY1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ETS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ETS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2480,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of AK8. Does perturbing IGDCC3 lead to a significant change in AK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of AK8. Does perturbing IGDCC3 lead to a significant change in AK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and COTL1 expression is quantified. Does this perturbation result in a significant change in COTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and COTL1 expression is quantified. Does this perturbation result in a significant change in COTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of LINC01342. Does perturbing CELF2 lead to a significant change in LINC01342 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of LINC01342. Does perturbing CELF2 lead to a significant change in LINC01342 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of TTC9B. Does this perturbation cause a significant change in TTC9B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of TTC9B. Does this perturbation cause a significant change in TTC9B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Determine whether RP11-259K5.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Determine whether RP11-259K5.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 388,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CPXM1 expression. Decide whether this perturbation leads to a significant alteration in CPXM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CPXM1 expression. Decide whether this perturbation leads to a significant alteration in CPXM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CREB3L2. Does this perturbation cause a significant change in CREB3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CREB3L2. Does this perturbation cause a significant change in CREB3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4970,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ZNF677 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ZNF677 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1218,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor AC020571.3 expression. Decide whether this perturbation leads to a significant alteration in AC020571.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor AC020571.3 expression. Decide whether this perturbation leads to a significant alteration in AC020571.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in FAM49A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in FAM49A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Determine whether CBL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Determine whether CBL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2408,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SLC20A1 expression. Decide whether this perturbation leads to a significant alteration in SLC20A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SLC20A1 expression. Decide whether this perturbation leads to a significant alteration in SLC20A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3233,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and SH3RF2 expression is observed. Does this perturbation lead to a significant difference in SH3RF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and SH3RF2 expression is observed. Does this perturbation lead to a significant difference in SH3RF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Determine whether RP11-1085N6.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Determine whether RP11-1085N6.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6223,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CENPE expression is observed. Does this perturbation lead to a significant difference in CENPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CENPE expression is observed. Does this perturbation lead to a significant difference in CENPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of RP11-355B11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of RP11-355B11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4378,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and RNF182 expression is quantified. Does this perturbation result in a significant change in RNF182 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and RNF182 expression is quantified. Does this perturbation result in a significant change in RNF182 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1368,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor TOX expression. Decide whether this perturbation leads to a significant alteration in TOX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor TOX expression. Decide whether this perturbation leads to a significant alteration in TOX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in IL1RN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in IL1RN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PTRF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PTRF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is quantified. Does this perturbation result in a significant change in RP11-195B3.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is quantified. Does this perturbation result in a significant change in RP11-195B3.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and PCDHGA3 expression is quantified. Does this perturbation result in a significant change in PCDHGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and PCDHGA3 expression is quantified. Does this perturbation result in a significant change in PCDHGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of CST9L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of CST9L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3908,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor TNFRSF12A expression. Decide whether this perturbation leads to a significant alteration in TNFRSF12A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor TNFRSF12A expression. Decide whether this perturbation leads to a significant alteration in TNFRSF12A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2703,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-505P4.7. Does perturbing IER5L lead to a significant change in RP11-505P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-505P4.7. Does perturbing IER5L lead to a significant change in RP11-505P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Determine whether CST9L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Determine whether CST9L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and RASGRF2 expression is quantified. Does this perturbation result in a significant change in RASGRF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and RASGRF2 expression is quantified. Does this perturbation result in a significant change in RASGRF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5268,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and AC144568.2 expression is measured. Determine whether AC144568.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and AC144568.2 expression is measured. Determine whether AC144568.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of AC064834.2. Does this perturbation cause a significant change in AC064834.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of AC064834.2. Does this perturbation cause a significant change in AC064834.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is measured. Determine whether RPL17-C18orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is measured. Determine whether RPL17-C18orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 663,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and PTPRS expression is observed. Does this perturbation lead to a significant difference in PTPRS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and PTPRS expression is observed. Does this perturbation lead to a significant difference in PTPRS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of TNFAIP8. Does perturbing CELF2 lead to a significant change in TNFAIP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of TNFAIP8. Does perturbing CELF2 lead to a significant change in TNFAIP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5723,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ADGRF1 expression is observed. Does this perturbation lead to a significant difference in ADGRF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ADGRF1 expression is observed. Does this perturbation lead to a significant difference in ADGRF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5543,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ADGB expression is observed. Does this perturbation lead to a significant difference in ADGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ADGB expression is observed. Does this perturbation lead to a significant difference in ADGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 510,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Does this perturbation cause a significant change in ZNF85 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Does this perturbation cause a significant change in ZNF85 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4478,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 11,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of CLU. Does perturbing TSC22D1 lead to a significant change in CLU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of CLU. Does perturbing TSC22D1 lead to a significant change in CLU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4283,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CITED2 expression is observed. Does this perturbation lead to a significant difference in CITED2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CITED2 expression is observed. Does this perturbation lead to a significant difference in CITED2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1110,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Does this perturbation cause a significant change in C1orf228 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Does this perturbation cause a significant change in C1orf228 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Determine whether TOX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Determine whether TOX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ARRDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ARRDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4323,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of TUBB. Does perturbing TP73 lead to a significant change in TUBB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of TUBB. Does perturbing TP73 lead to a significant change in TUBB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4353,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and SLCO6A1 expression is observed. Does this perturbation lead to a significant difference in SLCO6A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and SLCO6A1 expression is observed. Does this perturbation lead to a significant difference in SLCO6A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ST3GAL5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ST3GAL5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CITED2 expression is measured. Determine whether CITED2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CITED2 expression is measured. Determine whether CITED2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of CCNG2. Does this perturbation cause a significant change in CCNG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of CCNG2. Does this perturbation cause a significant change in CCNG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of VCX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of VCX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3718,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of CTSW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of CTSW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5703,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of FAM19A2. Does perturbing SAMD1 lead to a significant change in FAM19A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of FAM19A2. Does perturbing SAMD1 lead to a significant change in FAM19A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of PXK. Does this perturbation cause a significant change in PXK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of PXK. Does this perturbation cause a significant change in PXK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CCNL1 expression is measured. Determine whether CCNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CCNL1 expression is measured. Determine whether CCNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 809,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and DDX58 expression is quantified. Does this perturbation result in a significant change in DDX58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and DDX58 expression is quantified. Does this perturbation result in a significant change in DDX58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1693,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and FMNL1 expression is observed. Does this perturbation lead to a significant difference in FMNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and FMNL1 expression is observed. Does this perturbation lead to a significant difference in FMNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 66,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 472,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and FAM49A expression is quantified. Does this perturbation result in a significant change in FAM49A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and FAM49A expression is quantified. Does this perturbation result in a significant change in FAM49A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 93,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and TDRD12 expression is observed. Does this perturbation lead to a significant difference in TDRD12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and TDRD12 expression is observed. Does this perturbation lead to a significant difference in TDRD12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3648,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor LTC4S expression. Decide whether this perturbation leads to a significant alteration in LTC4S expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor LTC4S expression. Decide whether this perturbation leads to a significant alteration in LTC4S expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SLC2A3. Does this perturbation cause a significant change in SLC2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SLC2A3. Does this perturbation cause a significant change in SLC2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1145,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2558,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-505P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-505P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of C1orf228. Does this perturbation cause a significant change in C1orf228 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of C1orf228. Does this perturbation cause a significant change in C1orf228 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'."