[
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1097
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CDK1 expression. Decide whether this perturbation leads to a significant alteration in CDK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CDK1 expression. Decide whether this perturbation leads to a significant alteration in CDK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4408
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SKAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SKAP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":715
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-1017G21.6. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-1017G21.6. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3824
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Determine whether RLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Determine whether RLN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5006
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2522
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2942
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5839
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01358 expression is observed. Does this perturbation lead to a significant difference in LINC01358 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01358 expression is observed. Does this perturbation lead to a significant difference in LINC01358 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5613
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3012
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of TSC22D4. Does this perturbation cause a significant change in TSC22D4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":194
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in DNAJB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3865
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in RABAC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in RABAC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5145
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Determine whether CFH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5446
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of LMNA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of LMNA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1687
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor LMNA expression. Decide whether this perturbation leads to a significant alteration in LMNA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor LMNA expression. Decide whether this perturbation leads to a significant alteration in LMNA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1688
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Does this perturbation cause a significant change in TUBA1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Does this perturbation cause a significant change in TUBA1A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2710
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and MKNK2 expression is quantified. Does this perturbation result in a significant change in MKNK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and MKNK2 expression is quantified. Does this perturbation result in a significant change in MKNK2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1622
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4828
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of SLC38A2. Does this perturbation cause a significant change in SLC38A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of SLC38A2. Does this perturbation cause a significant change in SLC38A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5694
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor PDE1B expression. Decide whether this perturbation leads to a significant alteration in PDE1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor PDE1B expression. Decide whether this perturbation leads to a significant alteration in PDE1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":38
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in TAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in TAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3805
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and SPTAN1 expression is observed. Does this perturbation lead to a significant difference in SPTAN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and SPTAN1 expression is observed. Does this perturbation lead to a significant difference in SPTAN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2163
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor STAC3 expression. Decide whether this perturbation leads to a significant alteration in STAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor STAC3 expression. Decide whether this perturbation leads to a significant alteration in STAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":278
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ARMCX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ARMCX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3975
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":244
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3153
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in VCX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in VCX3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":155
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1816
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and H1FNT expression is observed. Does this perturbation lead to a significant difference in H1FNT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and H1FNT expression is observed. Does this perturbation lead to a significant difference in H1FNT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2913
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2223
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Does this perturbation cause a significant change in FAM46C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Does this perturbation cause a significant change in FAM46C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2890
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD47. Does perturbing ETS2 lead to a significant change in CD47 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD47. Does perturbing ETS2 lead to a significant change in CD47 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":781
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of DLX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of DLX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6167
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3502
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of RP11-452C8.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of RP11-452C8.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4077
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and TAC3 expression is measured. Determine whether TAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and TAC3 expression is measured. Determine whether TAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3809
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and RETN expression is observed. Does this perturbation lead to a significant difference in RETN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and RETN expression is observed. Does this perturbation lead to a significant difference in RETN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2453
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and TTC9B expression is observed. Does this perturbation lead to a significant difference in TTC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and TTC9B expression is observed. Does this perturbation lead to a significant difference in TTC9B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4493
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PPFIA4 expression is observed. Does this perturbation lead to a significant difference in PPFIA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PPFIA4 expression is observed. Does this perturbation lead to a significant difference in PPFIA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5303
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Does this perturbation cause a significant change in AC145110.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Does this perturbation cause a significant change in AC145110.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3110
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and AGXT expression is measured. Determine whether AGXT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and AGXT expression is measured. Determine whether AGXT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1059
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TMEM55A. Does perturbing KIF2C lead to a significant change in TMEM55A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TMEM55A. Does perturbing KIF2C lead to a significant change in TMEM55A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4601
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of KRTAP9-9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of KRTAP9-9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5297
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5150
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of SERPINF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of SERPINF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1087
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ATG2A expression. Decide whether this perturbation leads to a significant alteration in ATG2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ATG2A expression. Decide whether this perturbation leads to a significant alteration in ATG2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3638
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and PTPRS expression is quantified. Does this perturbation result in a significant change in PTPRS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and PTPRS expression is quantified. Does this perturbation result in a significant change in PTPRS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":662
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5024
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3320
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and AC139099.6 expression is quantified. Does this perturbation result in a significant change in AC139099.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and AC139099.6 expression is quantified. Does this perturbation result in a significant change in AC139099.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3472
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TPM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4515
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1277
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Determine whether HCN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Determine whether HCN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3046
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5984
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and S100A13 expression is observed. Does this perturbation lead to a significant difference in S100A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1823
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3329
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2788
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of LBH. Does this perturbation cause a significant change in LBH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of LBH. Does this perturbation cause a significant change in LBH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5934
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and HEATR9 expression is measured. Determine whether HEATR9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and HEATR9 expression is measured. Determine whether HEATR9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2389
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of AK8. Does this perturbation cause a significant change in AK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of AK8. Does this perturbation cause a significant change in AK8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4394
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and TAS1R1 expression is observed. Does this perturbation lead to a significant difference in TAS1R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and TAS1R1 expression is observed. Does this perturbation lead to a significant difference in TAS1R1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":703
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and CAPG expression is observed. Does this perturbation lead to a significant difference in CAPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and CAPG expression is observed. Does this perturbation lead to a significant difference in CAPG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4873
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4885
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1652
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3308
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ABCA13. Does this perturbation cause a significant change in ABCA13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ABCA13. Does this perturbation cause a significant change in ABCA13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2094
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ATP10D expression is observed. Does this perturbation lead to a significant difference in ATP10D expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2923
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and RP4-565E6.1 expression is observed. Does this perturbation lead to a significant difference in RP4-565E6.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and RP4-565E6.1 expression is observed. Does this perturbation lead to a significant difference in RP4-565E6.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":293
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and AC145110.1 expression is measured. Determine whether AC145110.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and AC145110.1 expression is measured. Determine whether AC145110.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3119
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Determine whether SH3RF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3236
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is quantified. Does this perturbation result in a significant change in CTD-3126B10.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is quantified. Does this perturbation result in a significant change in CTD-3126B10.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2392
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of FBXL20. Does perturbing PTPN9 lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of FBXL20. Does perturbing PTPN9 lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5761
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Determine whether TEX30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Determine whether TEX30 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2416
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of FEV. Does perturbing MAP4K5 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of FEV. Does perturbing MAP4K5 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1321
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLEKHO1 expression is observed. Does this perturbation lead to a significant difference in PLEKHO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLEKHO1 expression is observed. Does this perturbation lead to a significant difference in PLEKHO1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6123
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of SPANXD. Does this perturbation cause a significant change in SPANXD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of SPANXD. Does this perturbation cause a significant change in SPANXD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4194
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1458
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and CCNG2 expression is observed. Does this perturbation lead to a significant difference in CCNG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and CCNG2 expression is observed. Does this perturbation lead to a significant difference in CCNG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4063
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of TDRD12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of TDRD12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":97
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":8
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RPL17-C18orf32 expression. Decide whether this perturbation leads to a significant alteration in RPL17-C18orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RPL17-C18orf32 expression. Decide whether this perturbation leads to a significant alteration in RPL17-C18orf32 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5778
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of DPYSL2. Does perturbing SNAI1 lead to a significant change in DPYSL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of DPYSL2. Does perturbing SNAI1 lead to a significant change in DPYSL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5801
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MYOZ3 expression is measured. Determine whether MYOZ3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MYOZ3 expression is measured. Determine whether MYOZ3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3949
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of RNF182 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of RNF182 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3957
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCM2L. Does this perturbation cause a significant change in CCM2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCM2L. Does this perturbation cause a significant change in CCM2L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2144
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RPL17-C18orf32. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RPL17-C18orf32. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5774
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1567
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and PLEK expression is measured. Determine whether PLEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and PLEK expression is measured. Determine whether PLEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5099
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3553
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3079
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":323
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of GPR157 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of GPR157 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3057
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-219B4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-219B4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1777
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and TEX30 expression is observed. Does this perturbation lead to a significant difference in TEX30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and TEX30 expression is observed. Does this perturbation lead to a significant difference in TEX30 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2413
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Determine whether THBS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3216
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of MYL4. Does perturbing ZBTB10 lead to a significant change in MYL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of MYL4. Does perturbing ZBTB10 lead to a significant change in MYL4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5561
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ITGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of ITGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4137
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Does this perturbation cause a significant change in RP6-159A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Does this perturbation cause a significant change in RP6-159A1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2820
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in HEATR9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in HEATR9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2385
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is quantified. Does this perturbation result in a significant change in RP11-445O3.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is quantified. Does this perturbation result in a significant change in RP11-445O3.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":42
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CITED2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CITED2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4285
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Determine whether MYLIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Determine whether MYLIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1236
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Does this perturbation cause a significant change in DCAF13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Does this perturbation cause a significant change in DCAF13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3540
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of TAS2R9. Does this perturbation cause a significant change in TAS2R9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of TAS2R9. Does this perturbation cause a significant change in TAS2R9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":894
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Determine whether DYNLL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Determine whether DYNLL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2816
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":499
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1815
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3567
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SLC2A3 expression is measured. Determine whether SLC2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SLC2A3 expression is measured. Determine whether SLC2A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2539
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and FAM46C expression is measured. Determine whether FAM46C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and FAM46C expression is measured. Determine whether FAM46C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2899
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in MMP19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in MMP19 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":945
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of EGOT. Does perturbing PTPN13 lead to a significant change in EGOT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of EGOT. Does perturbing PTPN13 lead to a significant change in EGOT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5671
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ABCA13 expression is observed. Does this perturbation lead to a significant difference in ABCA13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ABCA13 expression is observed. Does this perturbation lead to a significant difference in ABCA13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2093
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of AFMID. Does perturbing JUN lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of AFMID. Does perturbing JUN lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5501
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LST1. Does perturbing ZBTB25 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LST1. Does perturbing ZBTB25 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1261
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and FAM19A2 expression is quantified. Does this perturbation result in a significant change in FAM19A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and FAM19A2 expression is quantified. Does this perturbation result in a significant change in FAM19A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3362
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1274
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of RP3-525N10.2. Does perturbing HOXA13 lead to a significant change in RP3-525N10.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of RP3-525N10.2. Does perturbing HOXA13 lead to a significant change in RP3-525N10.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5891
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of SLC22A13. Does this perturbation cause a significant change in SLC22A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of SLC22A13. Does this perturbation cause a significant change in SLC22A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4004
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of SLC4A3. Does this perturbation cause a significant change in SLC4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of SLC4A3. Does this perturbation cause a significant change in SLC4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6084
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1327
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Does this perturbation cause a significant change in CTC-490E21.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Does this perturbation cause a significant change in CTC-490E21.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":570
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ACE expression is observed. Does this perturbation lead to a significant difference in ACE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3653
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of CSF3R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5577
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of GRAP2. Does perturbing FOXA1 lead to a significant change in GRAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of GRAP2. Does perturbing FOXA1 lead to a significant change in GRAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":311
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of AC016629.3. Does perturbing FOXA1 lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of AC016629.3. Does perturbing FOXA1 lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":321
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP11-345P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-345P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP11-345P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-345P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2873
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in SLC38A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in SLC38A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5695
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3450
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of CSF3R. Does this perturbation cause a significant change in CSF3R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5574
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2368
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP3-510H16.3. Does perturbing ARRDC3 lead to a significant change in RP3-510H16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP3-510H16.3. Does perturbing ARRDC3 lead to a significant change in RP3-510H16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3831
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1580
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of PHACTR1. Does this perturbation cause a significant change in PHACTR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of PHACTR1. Does this perturbation cause a significant change in PHACTR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4384
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ATP9A expression is measured. Determine whether ATP9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ATP9A expression is measured. Determine whether ATP9A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":539
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-328J14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-328J14.1 expression is observed. Does this perturbation lead to a significant difference in RP11-328J14.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2573
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4526
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4804
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and AKAP13 expression is quantified. Does this perturbation result in a significant change in AKAP13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and AKAP13 expression is quantified. Does this perturbation result in a significant change in AKAP13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3982
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CMB9-22P13.1. Does perturbing CDKN1B lead to a significant change in CMB9-22P13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CMB9-22P13.1. Does perturbing CDKN1B lead to a significant change in CMB9-22P13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5391
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in TUBB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in TUBB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2645
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CCDC159 expression is quantified. Does this perturbation result in a significant change in CCDC159 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CCDC159 expression is quantified. Does this perturbation result in a significant change in CCDC159 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4252
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of MFGE8. Does perturbing CITED1 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of MFGE8. Does perturbing CITED1 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5941
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ZIC4. Does perturbing PTPN12 lead to a significant change in ZIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of ZIC4. Does perturbing PTPN12 lead to a significant change in ZIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2611
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Determine whether ARHGEF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Determine whether ARHGEF6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2116
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Does this perturbation cause a significant change in RP11-320G24.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Does this perturbation cause a significant change in RP11-320G24.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5060
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4983
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in RP11-286H15.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in RP11-286H15.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2515
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TPP1 expression. Decide whether this perturbation leads to a significant alteration in TPP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TPP1 expression. Decide whether this perturbation leads to a significant alteration in TPP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1578
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Determine whether SLC38A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Determine whether SLC38A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5696
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of GPR157. Does this perturbation cause a significant change in GPR157 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of GPR157. Does this perturbation cause a significant change in GPR157 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3054
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of HMGA2. Does this perturbation cause a significant change in HMGA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of HMGA2. Does this perturbation cause a significant change in HMGA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3894
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3374
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Determine whether NUCB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Determine whether NUCB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3136
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of MYC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of MYC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3027
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4547
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and UBASH3B expression is observed. Does this perturbation lead to a significant difference in UBASH3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1403
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2750
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3370
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor MYLIP expression. Decide whether this perturbation leads to a significant alteration in MYLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor MYLIP expression. Decide whether this perturbation leads to a significant alteration in MYLIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1238
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RP4-550H1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RP4-550H1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5797
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is measured. Determine whether RP11-1017G21.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is measured. Determine whether RP11-1017G21.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3829
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Does this perturbation cause a significant change in IER3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Does this perturbation cause a significant change in IER3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2760
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":902
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of AGXT. Does this perturbation cause a significant change in AGXT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of AGXT. Does this perturbation cause a significant change in AGXT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1054
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and TOX expression is measured. Determine whether TOX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and TOX expression is measured. Determine whether TOX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1369
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in CHST15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in CHST15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2495
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in CPVL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in CPVL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4935
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CHI3L2. Does perturbing TBX3 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CHI3L2. Does perturbing TBX3 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":901
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SOCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SOCS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":697
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and RIMBP3C expression is observed. Does this perturbation lead to a significant difference in RIMBP3C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and RIMBP3C expression is observed. Does this perturbation lead to a significant difference in RIMBP3C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3283
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and PKIG expression is observed. Does this perturbation lead to a significant difference in PKIG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and PKIG expression is observed. Does this perturbation lead to a significant difference in PKIG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":203
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and RP11-968A15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-968A15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and RP11-968A15.2 expression is observed. Does this perturbation lead to a significant difference in RP11-968A15.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":833
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3488
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of TOR3A. Does this perturbation cause a significant change in TOR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of TOR3A. Does this perturbation cause a significant change in TOR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5344
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor TRGVA expression. Decide whether this perturbation leads to a significant alteration in TRGVA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor TRGVA expression. Decide whether this perturbation leads to a significant alteration in TRGVA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":958
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":429
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TMEM55A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TMEM55A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4605
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and RP11-6D1.3 expression is observed. Does this perturbation lead to a significant difference in RP11-6D1.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and RP11-6D1.3 expression is observed. Does this perturbation lead to a significant difference in RP11-6D1.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4013
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3305
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of FCER1G. Does perturbing ISL2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of FCER1G. Does perturbing ISL2 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and VASH1 expression is quantified. Does this perturbation result in a significant change in VASH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and VASH1 expression is quantified. Does this perturbation result in a significant change in VASH1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3352
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1262
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5987
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and PXK expression is quantified. Does this perturbation result in a significant change in PXK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and PXK expression is quantified. Does this perturbation result in a significant change in PXK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2172
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of MYLIP. Does perturbing COL2A1 lead to a significant change in MYLIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of MYLIP. Does perturbing COL2A1 lead to a significant change in MYLIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1231
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2044
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and TPH2 expression is observed. Does this perturbation lead to a significant difference in TPH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and TPH2 expression is observed. Does this perturbation lead to a significant difference in TPH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3413
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in TMEM35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in TMEM35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5015
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of TM4SF1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of TM4SF1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3757
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is quantified. Does this perturbation result in a significant change in RP11-290L1.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is quantified. Does this perturbation result in a significant change in RP11-290L1.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2032
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":24
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of KIF2C. Does this perturbation cause a significant change in KIF2C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4564
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLEKHO1. Does perturbing KIF18B lead to a significant change in PLEKHO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLEKHO1. Does perturbing KIF18B lead to a significant change in PLEKHO1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6121
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in AIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in AIM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3125
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Does this perturbation cause a significant change in ATP10D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Does this perturbation cause a significant change in ATP10D expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2920
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and RP1-59D14.10 expression is observed. Does this perturbation lead to a significant difference in RP1-59D14.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and RP1-59D14.10 expression is observed. Does this perturbation lead to a significant difference in RP1-59D14.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3773
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Determine whether CSF3R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5576
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of LHX1. Does this perturbation cause a significant change in LHX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":614
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":995
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of STRA6. Does perturbing BAK1 lead to a significant change in STRA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of STRA6. Does perturbing BAK1 lead to a significant change in STRA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":651
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of SPTAN1. Does this perturbation cause a significant change in SPTAN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of SPTAN1. Does this perturbation cause a significant change in SPTAN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2164
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of FOXF1. Does perturbing FOXF1 lead to a significant change in FOXF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3491
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is measured. Determine whether CTD-2527I21.14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is measured. Determine whether CTD-2527I21.14 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4419
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Determine whether RP11-76E17.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Determine whether RP11-76E17.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3346
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2390
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4046
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and TDRD12 expression is quantified. Does this perturbation result in a significant change in TDRD12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and TDRD12 expression is quantified. Does this perturbation result in a significant change in TDRD12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":92
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ASIC4 expression. Decide whether this perturbation leads to a significant alteration in ASIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor ASIC4 expression. Decide whether this perturbation leads to a significant alteration in ASIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2248
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5682
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Determine whether VGF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Determine whether VGF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":266
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5104
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Does this perturbation cause a significant change in CCNG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Does this perturbation cause a significant change in CCNG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4060
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3487
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":58
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZC3HAV1. Does perturbing CKS1B lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZC3HAV1. Does perturbing CKS1B lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3191
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Does this perturbation cause a significant change in TAS2R9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Does this perturbation cause a significant change in TAS2R9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":890
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CD52. Does perturbing EGR1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CD52. Does perturbing EGR1 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6181
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":563
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ADGRF1 expression is measured. Determine whether ADGRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and ADGRF1 expression is measured. Determine whether ADGRF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5729
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZEB2. Does perturbing CKS1B lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of ZEB2. Does perturbing CKS1B lead to a significant change in ZEB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3201
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and RP11-662J14.2 expression is observed. Does this perturbation lead to a significant difference in RP11-662J14.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and RP11-662J14.2 expression is observed. Does this perturbation lead to a significant difference in RP11-662J14.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5243
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Does this perturbation cause a significant change in DNAJB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Does this perturbation cause a significant change in DNAJB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3860
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4324
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ASIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of ASIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2247
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCM2L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCM2L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2147
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1028
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1924
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TRIM31 expression is quantified. Does this perturbation result in a significant change in TRIM31 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TRIM31 expression is quantified. Does this perturbation result in a significant change in TRIM31 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":462
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and CEBPA expression is observed. Does this perturbation lead to a significant difference in CEBPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and CEBPA expression is observed. Does this perturbation lead to a significant difference in CEBPA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1633
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of AMPH. Does perturbing PRDM1 lead to a significant change in AMPH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of AMPH. Does perturbing PRDM1 lead to a significant change in AMPH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6011
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM83F. Does perturbing TP73 lead to a significant change in FAM83F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM83F. Does perturbing TP73 lead to a significant change in FAM83F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2681
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ZMYND15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in ZMYND15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2735
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and FAM49A expression is measured. Determine whether FAM49A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and FAM49A expression is measured. Determine whether FAM49A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":479
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of CHST15. Does perturbing TBX2 lead to a significant change in CHST15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of CHST15. Does perturbing TBX2 lead to a significant change in CHST15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2491
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of LEFTY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of LEFTY1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5917
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTSL expression is quantified. Does this perturbation result in a significant change in CTSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1092
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and IER3 expression is quantified. Does this perturbation result in a significant change in IER3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and IER3 expression is quantified. Does this perturbation result in a significant change in IER3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2762
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CCNL1. Does this perturbation cause a significant change in CCNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of CCNL1. Does this perturbation cause a significant change in CCNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6144
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4156
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA5 expression. Decide whether this perturbation leads to a significant alteration in ANXA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA5 expression. Decide whether this perturbation leads to a significant alteration in ANXA5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2858
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and VCX3B expression is observed. Does this perturbation lead to a significant difference in VCX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and VCX3B expression is observed. Does this perturbation lead to a significant difference in VCX3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":153
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Does this perturbation cause a significant change in SAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1800
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor RP11-714G18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-714G18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor RP11-714G18.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-714G18.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1858
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is quantified. Does this perturbation result in a significant change in RP11-290K4.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is quantified. Does this perturbation result in a significant change in RP11-290K4.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3702
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2987
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2529
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2849
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and PXK expression is measured. Determine whether PXK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and PXK expression is measured. Determine whether PXK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2179
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of PTPRS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of PTPRS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":667
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of DDX58. Does this perturbation cause a significant change in DDX58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of DDX58. Does this perturbation cause a significant change in DDX58 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":224
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01395 expression is observed. Does this perturbation lead to a significant difference in LINC01395 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and LINC01395 expression is observed. Does this perturbation lead to a significant difference in LINC01395 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5593
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ZIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in ZIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2615
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and SLC38A2 expression is quantified. Does this perturbation result in a significant change in SLC38A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and SLC38A2 expression is quantified. Does this perturbation result in a significant change in SLC38A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5692
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor LRRC36 expression. Decide whether this perturbation leads to a significant alteration in LRRC36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor LRRC36 expression. Decide whether this perturbation leads to a significant alteration in LRRC36 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":338
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in RP1-59D14.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in RP1-59D14.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3775
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Does this perturbation cause a significant change in ABCB11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Does this perturbation cause a significant change in ABCB11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1660
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and POC1B-GALNT4 expression is observed. Does this perturbation lead to a significant difference in POC1B-GALNT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and POC1B-GALNT4 expression is observed. Does this perturbation lead to a significant difference in POC1B-GALNT4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1973
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PCDHGA6. Does perturbing ZBTB25 lead to a significant change in PCDHGA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PCDHGA6. Does perturbing ZBTB25 lead to a significant change in PCDHGA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1301
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CTD-2527I21.14. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CTD-2527I21.14. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4414
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4546
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C6orf1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C6orf1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1875
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and TACC1 expression is measured. Determine whether TACC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and TACC1 expression is measured. Determine whether TACC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6009
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4753
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of SIGLEC15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of SIGLEC15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1967
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and VASH1 expression is observed. Does this perturbation lead to a significant difference in VASH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and VASH1 expression is observed. Does this perturbation lead to a significant difference in VASH1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3353
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2958
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SLC20A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SLC20A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2405
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and VGF expression is quantified. Does this perturbation result in a significant change in VGF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and VGF expression is quantified. Does this perturbation result in a significant change in VGF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":262
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in PKIG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in PKIG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":205
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4476
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in UCKL1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in UCKL1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5255
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of YPEL3. Does this perturbation cause a significant change in YPEL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of YPEL3. Does this perturbation cause a significant change in YPEL3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5754
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Does this perturbation cause a significant change in CPXM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Does this perturbation cause a significant change in CPXM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":380
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is quantified. Does this perturbation result in a significant change in RP11-355B11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is quantified. Does this perturbation result in a significant change in RP11-355B11.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1172
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1640
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of MYB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of MYB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2107
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of BTG2. Does perturbing POU3F2 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of BTG2. Does perturbing POU3F2 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2041
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in RGS16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":215
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C8orf22 expression is quantified. Does this perturbation result in a significant change in C8orf22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C8orf22 expression is quantified. Does this perturbation result in a significant change in C8orf22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1892
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4083
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RP5-1142A6.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RP5-1142A6.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4717
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and COL18A1-AS1 expression is observed. Does this perturbation lead to a significant difference in COL18A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and COL18A1-AS1 expression is observed. Does this perturbation lead to a significant difference in COL18A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":633
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Determine whether RP11-91A18.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Determine whether RP11-91A18.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2696
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ABCB11 expression is observed. Does this perturbation lead to a significant difference in ABCB11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and ABCB11 expression is observed. Does this perturbation lead to a significant difference in ABCB11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1663
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01395. Does perturbing ZBTB10 lead to a significant change in LINC01395 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01395. Does perturbing ZBTB10 lead to a significant change in LINC01395 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5591
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4962
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor INHBE expression. Decide whether this perturbation leads to a significant alteration in INHBE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor INHBE expression. Decide whether this perturbation leads to a significant alteration in INHBE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5788
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Determine whether MSX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Determine whether MSX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4036
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of AC074289.1. Does perturbing DLX2 lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of AC074289.1. Does perturbing DLX2 lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1611
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of KRTAP9-9. Does perturbing ATL1 lead to a significant change in KRTAP9-9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of KRTAP9-9. Does perturbing ATL1 lead to a significant change in KRTAP9-9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5291
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3019
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor CTSW expression. Decide whether this perturbation leads to a significant alteration in CTSW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor CTSW expression. Decide whether this perturbation leads to a significant alteration in CTSW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5368
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1325
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Does this perturbation cause a significant change in CHP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Does this perturbation cause a significant change in CHP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5460
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of IGHEP2. Does perturbing ZBTB1 lead to a significant change in IGHEP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of IGHEP2. Does perturbing ZBTB1 lead to a significant change in IGHEP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3581
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CKS2. Does perturbing POU3F2 lead to a significant change in CKS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CKS2. Does perturbing POU3F2 lead to a significant change in CKS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2071
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Does this perturbation cause a significant change in RP11-662J14.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Does this perturbation cause a significant change in RP11-662J14.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5240
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ATF6B expression. Decide whether this perturbation leads to a significant alteration in ATF6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ATF6B expression. Decide whether this perturbation leads to a significant alteration in ATF6B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5328
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RGPD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RGPD5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5967
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":27
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and AKAP13 expression is measured. Determine whether AKAP13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and AKAP13 expression is measured. Determine whether AKAP13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3989
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4238
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FCER1G. Does perturbing PTPN13 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FCER1G. Does perturbing PTPN13 lead to a significant change in FCER1G expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5641
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FAM101B. Does perturbing FOXA1 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of FAM101B. Does perturbing FOXA1 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":301
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4467
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of FABP5. Does perturbing POU3F2 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of FABP5. Does perturbing POU3F2 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2051
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ESAM. Does perturbing KIAA1804 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ESAM. Does perturbing KIAA1804 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4151
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Determine whether RGS16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":216
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor STRA6 expression. Decide whether this perturbation leads to a significant alteration in STRA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor STRA6 expression. Decide whether this perturbation leads to a significant alteration in STRA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":658
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of FAM46C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of FAM46C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2897
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Determine whether PRKAG2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Determine whether PRKAG2-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3166
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is measured. Determine whether RP11-445O3.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP11-445O3.3 expression is measured. Determine whether RP11-445O3.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":49
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and FILIP1L expression is quantified. Does this perturbation result in a significant change in FILIP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and FILIP1L expression is quantified. Does this perturbation result in a significant change in FILIP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2262
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Does this perturbation cause a significant change in SLC7A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Does this perturbation cause a significant change in SLC7A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4890
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of CTNNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":507
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CD46 expression is measured. Determine whether CD46 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4209
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":726
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of RABAC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of RABAC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5147
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in IER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in IER3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2765
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":427
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Determine whether KIF2C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4566
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of NCALD. Does perturbing UBASH3A lead to a significant change in NCALD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of NCALD. Does perturbing UBASH3A lead to a significant change in NCALD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4831
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2882
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Does this perturbation cause a significant change in FNDC3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Does this perturbation cause a significant change in FNDC3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4580
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4776
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Does this perturbation cause a significant change in CCNB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Does this perturbation cause a significant change in CCNB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4330
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and EMP3 expression is measured. Determine whether EMP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and EMP3 expression is measured. Determine whether EMP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3039
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and LRRC36 expression is observed. Does this perturbation lead to a significant difference in LRRC36 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and LRRC36 expression is observed. Does this perturbation lead to a significant difference in LRRC36 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":333
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of HMOX1. Does perturbing CITED1 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of HMOX1. Does perturbing CITED1 lead to a significant change in HMOX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5971
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CARMN. Does this perturbation cause a significant change in CARMN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CARMN. Does this perturbation cause a significant change in CARMN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3274
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ARHGEF6. Does this perturbation cause a significant change in ARHGEF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of ARHGEF6. Does this perturbation cause a significant change in ARHGEF6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2114
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Determine whether ANXA2R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Determine whether ANXA2R shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5876
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4085
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Does this perturbation cause a significant change in COLGALT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4090
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and NUCB2 expression is quantified. Does this perturbation result in a significant change in NUCB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and NUCB2 expression is quantified. Does this perturbation result in a significant change in NUCB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3132
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor HEATR9 expression. Decide whether this perturbation leads to a significant alteration in HEATR9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor HEATR9 expression. Decide whether this perturbation leads to a significant alteration in HEATR9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2388
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor APOL6 expression. Decide whether this perturbation leads to a significant alteration in APOL6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor APOL6 expression. Decide whether this perturbation leads to a significant alteration in APOL6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3428
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and PCDHGA3 expression is measured. Determine whether PCDHGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and PCDHGA3 expression is measured. Determine whether PCDHGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2569
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of GCM2. Does perturbing MAP4K5 lead to a significant change in GCM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of GCM2. Does perturbing MAP4K5 lead to a significant change in GCM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1351
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in RP3-525N10.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in RP3-525N10.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5895
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":374
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3918
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2887
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of S100A4. Does perturbing SLC4A1 lead to a significant change in S100A4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of S100A4. Does perturbing SLC4A1 lead to a significant change in S100A4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1041
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in PGA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in PGA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6035
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Determine whether RP11-345P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Determine whether RP11-345P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2876
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ITGA3 expression is measured. Determine whether ITGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and ITGA3 expression is measured. Determine whether ITGA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4139
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in RP11-6D1.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in RP11-6D1.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4015
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of C1orf228 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of C1orf228 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1117
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1392
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MBP. Does this perturbation cause a significant change in MBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MBP. Does this perturbation cause a significant change in MBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1004
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Does this perturbation cause a significant change in MS4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Does this perturbation cause a significant change in MS4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":980
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of SOCS1. Does perturbing UBASH3B lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of SOCS1. Does perturbing UBASH3B lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1391
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SAT1 expression is measured. Determine whether SAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1809
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and LEFTY2 expression is quantified. Does this perturbation result in a significant change in LEFTY2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and LEFTY2 expression is quantified. Does this perturbation result in a significant change in LEFTY2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4942
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Does this perturbation cause a significant change in MARCKS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Does this perturbation cause a significant change in MARCKS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4990
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ADGRF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of ADGRF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5727
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ACTC1 expression is quantified. Does this perturbation result in a significant change in ACTC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ACTC1 expression is quantified. Does this perturbation result in a significant change in ACTC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5372
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6053
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4629
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in TMEM154 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in TMEM154 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4145
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CCRL2. Does perturbing FOXA1 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CCRL2. Does perturbing FOXA1 lead to a significant change in CCRL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":341
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor TAPBP expression. Decide whether this perturbation leads to a significant alteration in TAPBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor TAPBP expression. Decide whether this perturbation leads to a significant alteration in TAPBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2238
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Does this perturbation cause a significant change in RP11-968A15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Does this perturbation cause a significant change in RP11-968A15.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":830
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is measured. Determine whether RP11-345P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is measured. Determine whether RP11-345P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2879
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is quantified. Does this perturbation result in a significant change in RP11-514P8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is quantified. Does this perturbation result in a significant change in RP11-514P8.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3692
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Does this perturbation cause a significant change in LINC01338 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Does this perturbation cause a significant change in LINC01338 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5070
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6187
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":920
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and N4BP2L2 expression is measured. Determine whether N4BP2L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and N4BP2L2 expression is measured. Determine whether N4BP2L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4229
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Determine whether TNFAIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Determine whether TNFAIP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5206
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1618
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of TNFAIP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of TNFAIP8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2187
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":26
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of MKNK2. Does this perturbation cause a significant change in MKNK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of MKNK2. Does this perturbation cause a significant change in MKNK2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1624
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of BST2. Does perturbing RUNX1T1 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of BST2. Does perturbing RUNX1T1 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1931
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of AREG. Does this perturbation cause a significant change in AREG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of AREG. Does this perturbation cause a significant change in AREG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2504
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RIT1. Does perturbing NCL lead to a significant change in RIT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RIT1. Does perturbing NCL lead to a significant change in RIT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4911
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4755
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor KCNH2 expression. Decide whether this perturbation leads to a significant alteration in KCNH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor KCNH2 expression. Decide whether this perturbation leads to a significant alteration in KCNH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3448
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RNF168 expression. Decide whether this perturbation leads to a significant alteration in RNF168 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RNF168 expression. Decide whether this perturbation leads to a significant alteration in RNF168 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":778
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and RP11-452C8.1 expression is observed. Does this perturbation lead to a significant difference in RP11-452C8.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and RP11-452C8.1 expression is observed. Does this perturbation lead to a significant difference in RP11-452C8.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4073
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is measured. Determine whether RP11-320G24.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is measured. Determine whether RP11-320G24.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5069
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of AIF1. Does perturbing HK2 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of AIF1. Does perturbing HK2 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6051
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Determine whether CSRNP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Determine whether CSRNP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4646
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of RELB. Does perturbing PTPN13 lead to a significant change in RELB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of RELB. Does perturbing PTPN13 lead to a significant change in RELB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5651
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Determine whether AC004051.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Determine whether AC004051.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1846
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in NCALD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in NCALD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4835
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PIM2. Does perturbing PTPN9 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of PIM2. Does perturbing PTPN9 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5741
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Does this perturbation cause a significant change in CTSS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Does this perturbation cause a significant change in CTSS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2020
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLA2G16. Does this perturbation cause a significant change in PLA2G16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLA2G16. Does this perturbation cause a significant change in PLA2G16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6154
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Does this perturbation cause a significant change in SLC22A25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Does this perturbation cause a significant change in SLC22A25 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1830
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of RP11-286H15.1. Does this perturbation cause a significant change in RP11-286H15.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of RP11-286H15.1. Does this perturbation cause a significant change in RP11-286H15.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2514
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4449
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Determine whether RP11-38J22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Determine whether RP11-38J22.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6076
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Does this perturbation cause a significant change in EWSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Does this perturbation cause a significant change in EWSAT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5310
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and IL20 expression is measured. Determine whether IL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and IL20 expression is measured. Determine whether IL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3769
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1329
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is quantified. Does this perturbation result in a significant change in RP11-452C8.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is quantified. Does this perturbation result in a significant change in RP11-452C8.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4072
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in RNF182 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in RNF182 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3955
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor AC145110.1 expression. Decide whether this perturbation leads to a significant alteration in AC145110.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor AC145110.1 expression. Decide whether this perturbation leads to a significant alteration in AC145110.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3118
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor CEBPA expression. Decide whether this perturbation leads to a significant alteration in CEBPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor CEBPA expression. Decide whether this perturbation leads to a significant alteration in CEBPA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1638
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Determine whether CDC20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5406
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and DLX4 expression is measured. Determine whether DLX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and DLX4 expression is measured. Determine whether DLX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6169
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01420 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01420 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5427
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01227 expression. Decide whether this perturbation leads to a significant alteration in LINC01227 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01227 expression. Decide whether this perturbation leads to a significant alteration in LINC01227 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5438
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5929
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and LEFTY2 expression is measured. Determine whether LEFTY2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and LEFTY2 expression is measured. Determine whether LEFTY2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4949
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CIB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CIB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5225
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in LINC01338 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in LINC01338 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5075
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and CBL expression is measured. Determine whether CBL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and CBL expression is measured. Determine whether CBL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3149
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":740
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5044
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor ZFP36L2 expression. Decide whether this perturbation leads to a significant alteration in ZFP36L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3678
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MS4A2. Does this perturbation cause a significant change in MS4A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MS4A2. Does this perturbation cause a significant change in MS4A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3934
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of POC1B-GALNT4. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of POC1B-GALNT4. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1974
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Determine whether LRP10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Determine whether LRP10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3316
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CYP2C18. Does this perturbation cause a significant change in CYP2C18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CYP2C18. Does this perturbation cause a significant change in CYP2C18 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":934
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor CCNB2 expression. Decide whether this perturbation leads to a significant alteration in CCNB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor CCNB2 expression. Decide whether this perturbation leads to a significant alteration in CCNB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4338
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of PYROXD2. Does perturbing STIL lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of PYROXD2. Does perturbing STIL lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5151
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4967
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and PSMB9 expression is observed. Does this perturbation lead to a significant difference in PSMB9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5283
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor THBS1 expression. Decide whether this perturbation leads to a significant alteration in THBS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3218
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1485
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of RP11-662J14.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of RP11-662J14.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5247
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Determine whether ABCA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Determine whether ABCA13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2096
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Determine whether CPXM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CPXM1 is measured. Determine whether CPXM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":386
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of HOXB6. Does this perturbation cause a significant change in HOXB6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of HOXB6. Does this perturbation cause a significant change in HOXB6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":814
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of SCG5. Does this perturbation cause a significant change in SCG5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5854
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of PHGDH. Does perturbing TMSB4X lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of PHGDH. Does perturbing TMSB4X lead to a significant change in PHGDH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4501
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MYOZ3. Does this perturbation cause a significant change in MYOZ3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of MYOZ3. Does this perturbation cause a significant change in MYOZ3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3944
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4884
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor CPVL expression. Decide whether this perturbation leads to a significant alteration in CPVL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor CPVL expression. Decide whether this perturbation leads to a significant alteration in CPVL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4938
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of HOXB6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of HOXB6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":817
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1746
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of PRKAG2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of PRKAG2-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3167
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Determine whether RIMBP3C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Determine whether RIMBP3C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3286
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":50
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor NUCB2 expression. Decide whether this perturbation leads to a significant alteration in NUCB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor NUCB2 expression. Decide whether this perturbation leads to a significant alteration in NUCB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3138
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and HIST1H3H expression is quantified. Does this perturbation result in a significant change in HIST1H3H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and HIST1H3H expression is quantified. Does this perturbation result in a significant change in HIST1H3H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5332
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in MME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in MME expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6265
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of TTC9B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of TTC9B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4497
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of FMNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of FMNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1697
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is quantified. Does this perturbation result in a significant change in CTD-2012K14.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is quantified. Does this perturbation result in a significant change in CTD-2012K14.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5212
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and RSPO4 expression is measured. Determine whether RSPO4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and RSPO4 expression is measured. Determine whether RSPO4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4119
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in CNN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in CNN2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4705
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in RP11-91A18.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in RP11-91A18.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2695
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1723
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CTD-2031P19.5. Does perturbing SET lead to a significant change in CTD-2031P19.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CTD-2031P19.5. Does perturbing SET lead to a significant change in CTD-2031P19.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":881
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in RLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in RLN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5005
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and MT1E expression is measured. Determine whether MT1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and MT1E expression is measured. Determine whether MT1E exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":369
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor SEMA3B expression. Decide whether this perturbation leads to a significant alteration in SEMA3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor SEMA3B expression. Decide whether this perturbation leads to a significant alteration in SEMA3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4248
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Does this perturbation cause a significant change in LHX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":610
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTC-492K19.4 expression. Decide whether this perturbation leads to a significant alteration in CTC-492K19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTC-492K19.4 expression. Decide whether this perturbation leads to a significant alteration in CTC-492K19.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1128
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":793
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4522
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of RP1-59D14.10. Does perturbing BPGM lead to a significant change in RP1-59D14.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of RP1-59D14.10. Does perturbing BPGM lead to a significant change in RP1-59D14.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3771
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CIB3 expression is measured. Determine whether CIB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CIB3 expression is measured. Determine whether CIB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5229
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":922
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of FBXL20. Does perturbing IER5L lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of FBXL20. Does perturbing IER5L lead to a significant change in FBXL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2521
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of BAK1. Does this perturbation cause a significant change in BAK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":624
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1926
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CREB3L2 expression is observed. Does this perturbation lead to a significant difference in CREB3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5993
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of DEK. Does perturbing CBFA2T3 lead to a significant change in DEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of DEK. Does perturbing CBFA2T3 lead to a significant change in DEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1671
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5633
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and DPYSL2 expression is measured. Determine whether DPYSL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and DPYSL2 expression is measured. Determine whether DPYSL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5809
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5108
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Determine whether CNN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Determine whether CNN2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4706
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CCRL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":345
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Does this perturbation cause a significant change in PROX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Does this perturbation cause a significant change in PROX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4050
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TRIM31 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TRIM31 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":467
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CTD-2527I21.14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CTD-2527I21.14 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4415
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of CTSS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of CTSS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2027
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Does this perturbation cause a significant change in CD37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Does this perturbation cause a significant change in CD37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3240
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TRIM31. Does this perturbation cause a significant change in TRIM31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TRIM31. Does this perturbation cause a significant change in TRIM31 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":464
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":325
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of C1orf141 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of C1orf141 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2337
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5928
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of UBASH3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1407
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA2. Does this perturbation cause a significant change in ANXA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA2. Does this perturbation cause a significant change in ANXA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2834
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Does this perturbation cause a significant change in VASH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Does this perturbation cause a significant change in VASH1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3350
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Does this perturbation cause a significant change in AC064834.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Does this perturbation cause a significant change in AC064834.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2440
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Determine whether SPANXN5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Determine whether SPANXN5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3466
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of FAM225B. Does perturbing CEBPB lead to a significant change in FAM225B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of FAM225B. Does perturbing CEBPB lead to a significant change in FAM225B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5231
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":74
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Does this perturbation cause a significant change in RP11-128B16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Does this perturbation cause a significant change in RP11-128B16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1790
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and CSF3R expression is measured. Determine whether CSF3R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5579
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of SOX4. Does perturbing CDKN1A lead to a significant change in SOX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of SOX4. Does perturbing CDKN1A lead to a significant change in SOX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2351
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3375
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4087
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of AKAP13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of AKAP13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3987
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of INHBE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of INHBE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5787
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TUBA1A expression is observed. Does this perturbation lead to a significant difference in TUBA1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TUBA1A expression is observed. Does this perturbation lead to a significant difference in TUBA1A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2713
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Does this perturbation cause a significant change in ZFP36L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3670
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CCRL2 expression is quantified. Does this perturbation result in a significant change in CCRL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":342
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2787
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":86
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2588
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6056
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6135
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of LINC00479. Does this perturbation cause a significant change in LINC00479 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of LINC00479. Does this perturbation cause a significant change in LINC00479 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":414
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and FABP3 expression is observed. Does this perturbation lead to a significant difference in FABP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and FABP3 expression is observed. Does this perturbation lead to a significant difference in FABP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3723
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1399
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of CTC-490E21.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of CTC-490E21.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":577
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor RHOXF2BB expression. Decide whether this perturbation leads to a significant alteration in RHOXF2BB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor RHOXF2BB expression. Decide whether this perturbation leads to a significant alteration in RHOXF2BB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5718
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and RGS16 expression is observed. Does this perturbation lead to a significant difference in RGS16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":213
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4544
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor HCAR2 expression. Decide whether this perturbation leads to a significant alteration in HCAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor HCAR2 expression. Decide whether this perturbation leads to a significant alteration in HCAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5198
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of AKAP13. Does perturbing MAP2K6 lead to a significant change in AKAP13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of AKAP13. Does perturbing MAP2K6 lead to a significant change in AKAP13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3981
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CHP1. Does this perturbation cause a significant change in CHP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CHP1. Does this perturbation cause a significant change in CHP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5464
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Does this perturbation cause a significant change in FAM83F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Does this perturbation cause a significant change in FAM83F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2680
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4473
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of RELB. Does this perturbation cause a significant change in RELB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of RELB. Does this perturbation cause a significant change in RELB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5654
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor TRAPPC3L expression. Decide whether this perturbation leads to a significant alteration in TRAPPC3L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor TRAPPC3L expression. Decide whether this perturbation leads to a significant alteration in TRAPPC3L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6258
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of KRTAP9-9. Does this perturbation cause a significant change in KRTAP9-9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of KRTAP9-9. Does this perturbation cause a significant change in KRTAP9-9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5294
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4638
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of CTSS. Does perturbing S1PR2 lead to a significant change in CTSS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of CTSS. Does perturbing S1PR2 lead to a significant change in CTSS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2021
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor VMP1 expression. Decide whether this perturbation leads to a significant alteration in VMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor VMP1 expression. Decide whether this perturbation leads to a significant alteration in VMP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5868
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4020
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and SH3BGRL expression is quantified. Does this perturbation result in a significant change in SH3BGRL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and SH3BGRL expression is quantified. Does this perturbation result in a significant change in SH3BGRL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":392
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5167
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ZMYND15. Does perturbing MAP7D1 lead to a significant change in ZMYND15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of ZMYND15. Does perturbing MAP7D1 lead to a significant change in ZMYND15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2731
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2883
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PSMB9 expression is quantified. Does this perturbation result in a significant change in PSMB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PSMB9 expression is quantified. Does this perturbation result in a significant change in PSMB9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5282
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of AC078941.1. Does perturbing S1PR2 lead to a significant change in AC078941.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of AC078941.1. Does perturbing S1PR2 lead to a significant change in AC078941.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2011
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ANXA3. Does this perturbation cause a significant change in ANXA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ANXA3. Does this perturbation cause a significant change in ANXA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3964
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3912
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Determine whether PCDHGA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Determine whether PCDHGA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1306
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3712
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is measured. Determine whether TFAP2A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is measured. Determine whether TFAP2A-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4369
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Does this perturbation cause a significant change in PPFIA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Does this perturbation cause a significant change in PPFIA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5300
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Does this perturbation cause a significant change in APOL6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Does this perturbation cause a significant change in APOL6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3420
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1159
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Determine whether LINC01562 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Determine whether LINC01562 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1316
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and AC139099.6 expression is observed. Does this perturbation lead to a significant difference in AC139099.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and AC139099.6 expression is observed. Does this perturbation lead to a significant difference in AC139099.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3473
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ORAI3. Does perturbing RUNX1T1 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of ORAI3. Does perturbing RUNX1T1 lead to a significant change in ORAI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1941
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and RP11-195C7.1 expression is measured. Determine whether RP11-195C7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and RP11-195C7.1 expression is measured. Determine whether RP11-195C7.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1739
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4213
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4764
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Determine whether ETS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Determine whether ETS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":586
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLEKHO1. Does this perturbation cause a significant change in PLEKHO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of PLEKHO1. Does this perturbation cause a significant change in PLEKHO1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6124
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4486
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of KRT79. Does this perturbation cause a significant change in KRT79 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of KRT79. Does this perturbation cause a significant change in KRT79 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3884
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and TAPBP expression is observed. Does this perturbation lead to a significant difference in TAPBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and TAPBP expression is observed. Does this perturbation lead to a significant difference in TAPBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2233
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MBP. Does perturbing LHX1 lead to a significant change in MBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MBP. Does perturbing LHX1 lead to a significant change in MBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1001
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and UNC5B expression is observed. Does this perturbation lead to a significant difference in UNC5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and UNC5B expression is observed. Does this perturbation lead to a significant difference in UNC5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3253
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1190
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2367
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and KRT79 expression is measured. Determine whether KRT79 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and KRT79 expression is measured. Determine whether KRT79 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3889
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2369
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor BAK1 expression. Decide whether this perturbation leads to a significant alteration in BAK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":628
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2584
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Does this perturbation cause a significant change in RETN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Does this perturbation cause a significant change in RETN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2450
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of SH3BGRL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of SH3BGRL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":397
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and FCGR3A expression is observed. Does this perturbation lead to a significant difference in FCGR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and FCGR3A expression is observed. Does this perturbation lead to a significant difference in FCGR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5603
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01358 expression. Decide whether this perturbation leads to a significant alteration in LINC01358 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01358 expression. Decide whether this perturbation leads to a significant alteration in LINC01358 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5618
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5082
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor AC007193.6 expression. Decide whether this perturbation leads to a significant alteration in AC007193.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor AC007193.6 expression. Decide whether this perturbation leads to a significant alteration in AC007193.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2638
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2063
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and PGA4 expression is measured. Determine whether PGA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and PGA4 expression is measured. Determine whether PGA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6039
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Determine whether DPYSL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Determine whether DPYSL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5806
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ARMCX3 expression is quantified. Does this perturbation result in a significant change in ARMCX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ARMCX3 expression is quantified. Does this perturbation result in a significant change in ARMCX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3972
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2780
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and SLC22A13 expression is quantified. Does this perturbation result in a significant change in SLC22A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and SLC22A13 expression is quantified. Does this perturbation result in a significant change in SLC22A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4002
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5836
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Does this perturbation cause a significant change in DDX58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Does this perturbation cause a significant change in DDX58 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":220
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Does this perturbation cause a significant change in SDSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Does this perturbation cause a significant change in SDSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2420
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ORAI3 expression is quantified. Does this perturbation result in a significant change in ORAI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and ORAI3 expression is quantified. Does this perturbation result in a significant change in ORAI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1942
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3554
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3738
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Determine whether CTD-3126B10.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CTD-3126B10.4 is measured. Determine whether CTD-3126B10.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2396
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FAM83A. Does perturbing PTPN13 lead to a significant change in FAM83A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of FAM83A. Does perturbing PTPN13 lead to a significant change in FAM83A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5621
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3840
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in AC145110.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in AC145110.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3115
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of LBH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of LBH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5937
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4950
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in STRA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in STRA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":655
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1150
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of NPW. Does this perturbation cause a significant change in NPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of NPW. Does this perturbation cause a significant change in NPW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6044
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Determine whether DYNLT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Determine whether DYNLT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2676
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":855
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Determine whether SLCO6A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Determine whether SLCO6A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4356
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Does this perturbation cause a significant change in RP11-285F7.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Does this perturbation cause a significant change in RP11-285F7.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4900
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":436
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ACP5. Does perturbing COL2A1 lead to a significant change in ACP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of ACP5. Does perturbing COL2A1 lead to a significant change in ACP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1201
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MBP expression is measured. Determine whether MBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MBP expression is measured. Determine whether MBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1009
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor TRPM2 expression. Decide whether this perturbation leads to a significant alteration in TRPM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor TRPM2 expression. Decide whether this perturbation leads to a significant alteration in TRPM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1428
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1619
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RUNX3 expression is quantified. Does this perturbation result in a significant change in RUNX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RUNX3 expression is quantified. Does this perturbation result in a significant change in RUNX3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5952
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CRYM expression is observed. Does this perturbation lead to a significant difference in CRYM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3843
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and CTD-2616J11.16 expression is observed. Does this perturbation lead to a significant difference in CTD-2616J11.16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and CTD-2616J11.16 expression is observed. Does this perturbation lead to a significant difference in CTD-2616J11.16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1193
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of TFAP2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of TFAP2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2317
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in HSD17B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in HSD17B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":145
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of POC1B-GALNT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of POC1B-GALNT4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1977
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and COL21A1 expression is measured. Determine whether COL21A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and COL21A1 expression is measured. Determine whether COL21A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4429
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":568
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of SLC38A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of SLC38A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5697
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP11-445O3.3. Does this perturbation cause a significant change in RP11-445O3.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP11-445O3.3. Does this perturbation cause a significant change in RP11-445O3.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":44
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and SP6 expression is observed. Does this perturbation lead to a significant difference in SP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and SP6 expression is observed. Does this perturbation lead to a significant difference in SP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1703
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1953
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4866
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of PSMB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of PSMB8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":107
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Determine whether RP11-180M15.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Determine whether RP11-180M15.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4436
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2986
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Determine whether HBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Determine whether HBE1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":446
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of PDE1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of PDE1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":37
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in DST expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2345
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of RP1-102K2.6. Does perturbing IRF1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of RP1-102K2.6. Does perturbing IRF1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2981
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is measured. Determine whether RP11-202A13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is measured. Determine whether RP11-202A13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4789
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Does this perturbation cause a significant change in GPR157 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Does this perturbation cause a significant change in GPR157 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3050
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in RP11-445F12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in RP11-445F12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":605
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ANXA2R expression is measured. Determine whether ANXA2R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and ANXA2R expression is measured. Determine whether ANXA2R exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5879
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA5. Does this perturbation cause a significant change in ANXA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of ANXA5. Does this perturbation cause a significant change in ANXA5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2854
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and LINC00479 expression is quantified. Does this perturbation result in a significant change in LINC00479 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and LINC00479 expression is quantified. Does this perturbation result in a significant change in LINC00479 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":412
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Determine whether RPS6KA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Determine whether RPS6KA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1606
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and FILIP1L expression is measured. Determine whether FILIP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and FILIP1L expression is measured. Determine whether FILIP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2269
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of RP11-290L1.2. Does perturbing S1PR2 lead to a significant change in RP11-290L1.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of RP11-290L1.2. Does perturbing S1PR2 lead to a significant change in RP11-290L1.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2031
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3569
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ACTB. Does perturbing POU3F2 lead to a significant change in ACTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ACTB. Does perturbing POU3F2 lead to a significant change in ACTB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2081
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of RP11-6D1.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of RP11-6D1.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4017
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of NUCB2. Does perturbing HOXC13 lead to a significant change in NUCB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of NUCB2. Does perturbing HOXC13 lead to a significant change in NUCB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3131
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5816
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3570
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3660
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01227 expression is quantified. Does this perturbation result in a significant change in LINC01227 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01227 expression is quantified. Does this perturbation result in a significant change in LINC01227 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5432
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and CCDC136 expression is observed. Does this perturbation lead to a significant difference in CCDC136 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and CCDC136 expression is observed. Does this perturbation lead to a significant difference in CCDC136 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5033
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ANTXR2 expression is quantified. Does this perturbation result in a significant change in ANTXR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and ANTXR2 expression is quantified. Does this perturbation result in a significant change in ANTXR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5582
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Determine whether LRRC74B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Determine whether LRRC74B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4656
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PSMB9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5287
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-128B16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-128B16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1797
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and HEATR9 expression is quantified. Does this perturbation result in a significant change in HEATR9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and HEATR9 expression is quantified. Does this perturbation result in a significant change in HEATR9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2382
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and RP1-59D14.10 expression is quantified. Does this perturbation result in a significant change in RP1-59D14.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and RP1-59D14.10 expression is quantified. Does this perturbation result in a significant change in RP1-59D14.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3772
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1866
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and CTA-384D8.34 expression is observed. Does this perturbation lead to a significant difference in CTA-384D8.34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and CTA-384D8.34 expression is observed. Does this perturbation lead to a significant difference in CTA-384D8.34 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":643
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3785
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and TXNIP expression is quantified. Does this perturbation result in a significant change in TXNIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4692
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of RETN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of RETN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2457
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is measured. Determine whether RP11-83A24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is measured. Determine whether RP11-83A24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":529
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ARMCX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ARMCX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3977
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2786
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AP1S2 expression is observed. Does this perturbation lead to a significant difference in AP1S2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4263
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and AC064834.2 expression is quantified. Does this perturbation result in a significant change in AC064834.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and AC064834.2 expression is quantified. Does this perturbation result in a significant change in AC064834.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2442
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5989
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor IGFL2 expression. Decide whether this perturbation leads to a significant alteration in IGFL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor IGFL2 expression. Decide whether this perturbation leads to a significant alteration in IGFL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5498
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ST3GAL5 expression. Decide whether this perturbation leads to a significant alteration in ST3GAL5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor ST3GAL5 expression. Decide whether this perturbation leads to a significant alteration in ST3GAL5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1768
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Does this perturbation cause a significant change in FOXL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3680
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of RP11-6D1.3. Does this perturbation cause a significant change in RP11-6D1.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of RP11-6D1.3. Does this perturbation cause a significant change in RP11-6D1.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4014
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and NPW expression is measured. Determine whether NPW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and NPW expression is measured. Determine whether NPW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6049
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of MAP7D1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2727
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Does this perturbation cause a significant change in AC078941.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Does this perturbation cause a significant change in AC078941.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2010
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of CBL. Does perturbing HOXC13 lead to a significant change in CBL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of CBL. Does perturbing HOXC13 lead to a significant change in CBL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3141
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor RP11-76E17.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-76E17.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor RP11-76E17.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-76E17.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3348
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM83F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM83F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2685
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2303
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Does this perturbation cause a significant change in PGA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Does this perturbation cause a significant change in PGA4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6030
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Does this perturbation cause a significant change in TNFRSF12A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Does this perturbation cause a significant change in TNFRSF12A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3900
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of DRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of DRC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5667
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4966
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and ZFP36L2 expression is quantified. Does this perturbation result in a significant change in ZFP36L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3672
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2964
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor CLU expression. Decide whether this perturbation leads to a significant alteration in CLU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor CLU expression. Decide whether this perturbation leads to a significant alteration in CLU expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":18
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2706
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2124
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Does this perturbation cause a significant change in CENPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Does this perturbation cause a significant change in CENPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6220
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5210
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1149
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of C17orf64. Does perturbing HES7 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of C17orf64. Does perturbing HES7 lead to a significant change in C17orf64 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1711
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor LBH expression. Decide whether this perturbation leads to a significant alteration in LBH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5938
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of INADL. Does this perturbation cause a significant change in INADL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of INADL. Does this perturbation cause a significant change in INADL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2254
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4548
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5506
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3016
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Determine whether SOX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Determine whether SOX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2356
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor AIM1 expression. Decide whether this perturbation leads to a significant alteration in AIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor AIM1 expression. Decide whether this perturbation leads to a significant alteration in AIM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3128
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor GRN expression. Decide whether this perturbation leads to a significant alteration in GRN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5888
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RGPD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RGPD5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5965
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ST3GAL5. Does this perturbation cause a significant change in ST3GAL5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of ST3GAL5. Does this perturbation cause a significant change in ST3GAL5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1764
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":437
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":748
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4850
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is quantified. Does this perturbation result in a significant change in XX-FW83563B9.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is quantified. Does this perturbation result in a significant change in XX-FW83563B9.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3292
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3552
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":89
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of AC007556.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of AC007556.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":827
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of STRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of STRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5907
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of IGHEP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of IGHEP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3587
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4468
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MYOZ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MYOZ3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3945
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM118A expression is quantified. Does this perturbation result in a significant change in FAM118A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM118A expression is quantified. Does this perturbation result in a significant change in FAM118A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2662
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and TTC9B expression is quantified. Does this perturbation result in a significant change in TTC9B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and TTC9B expression is quantified. Does this perturbation result in a significant change in TTC9B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4492
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and HOGA1 expression is quantified. Does this perturbation result in a significant change in HOGA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and HOGA1 expression is quantified. Does this perturbation result in a significant change in HOGA1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2862
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-646I6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-646I6.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1077
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of FILIP1L. Does this perturbation cause a significant change in FILIP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of FILIP1L. Does this perturbation cause a significant change in FILIP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2264
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Does this perturbation cause a significant change in MAOB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Does this perturbation cause a significant change in MAOB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1490
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in TRPM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in TRPM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1425
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of UNC5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of UNC5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3257
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ARMCX3. Does perturbing MAP2K6 lead to a significant change in ARMCX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ARMCX3. Does perturbing MAP2K6 lead to a significant change in ARMCX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3971
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and C17orf64 expression is measured. Determine whether C17orf64 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1719
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Does this perturbation cause a significant change in RP11-290K4.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Does this perturbation cause a significant change in RP11-290K4.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3700
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":243
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4043
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5924
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-109E24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-109E24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6215
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":792
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5832
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CTD-2031P19.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CTD-2031P19.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":885
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3076
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CCNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in CCNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6145
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor AREG expression. Decide whether this perturbation leads to a significant alteration in AREG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor AREG expression. Decide whether this perturbation leads to a significant alteration in AREG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2508
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Determine whether HMGA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Determine whether HMGA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3896
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01358 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01358 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5615
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3075
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of GPR35. Does perturbing LYL1 lead to a significant change in GPR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of GPR35. Does perturbing LYL1 lead to a significant change in GPR35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3921
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Determine whether LINC01227 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Determine whether LINC01227 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5436
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":974
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of FABP5. Does perturbing KMT2A lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of FABP5. Does perturbing KMT2A lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4321
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of FNDC3A. Does perturbing KIF2C lead to a significant change in FNDC3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of FNDC3A. Does perturbing KIF2C lead to a significant change in FNDC3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4581
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":65
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Does this perturbation cause a significant change in BAK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":620
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and COLGALT2 expression is quantified. Does this perturbation result in a significant change in COLGALT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4092
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is measured. Determine whether CMB9-22P13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is measured. Determine whether CMB9-22P13.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5399
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in DDX58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in DDX58 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":225
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2603
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Does this perturbation cause a significant change in ARRDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Does this perturbation cause a significant change in ARRDC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":230
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4217
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CFH expression is measured. Determine whether CFH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5449
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2947
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RCSD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1445
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Determine whether ADGRF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Determine whether ADGRF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5726
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor TFAP2A expression. Decide whether this perturbation leads to a significant alteration in TFAP2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor TFAP2A expression. Decide whether this perturbation leads to a significant alteration in TFAP2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2318
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Does this perturbation cause a significant change in BMP2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Does this perturbation cause a significant change in BMP2K expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1500
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Does this perturbation cause a significant change in BCL2L11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Does this perturbation cause a significant change in BCL2L11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4920
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and TAPBP expression is quantified. Does this perturbation result in a significant change in TAPBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and TAPBP expression is quantified. Does this perturbation result in a significant change in TAPBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2232
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is measured. Determine whether RP11-290K4.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-290K4.2 expression is measured. Determine whether RP11-290K4.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3709
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in GYPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3625
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Determine whether MSRB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Determine whether MSRB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2656
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CTD-2527I21.14 expression is observed. Does this perturbation lead to a significant difference in CTD-2527I21.14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CTD-2527I21.14 expression is observed. Does this perturbation lead to a significant difference in CTD-2527I21.14 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4413
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is measured. Determine whether CTC-490E21.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is measured. Determine whether CTC-490E21.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":579
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and HBG1 expression is measured. Determine whether HBG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and HBG1 expression is measured. Determine whether HBG1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5389
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2709
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in COL18A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in COL18A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":635
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of AC004051.2. Does perturbing FOXO4 lead to a significant change in AC004051.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of AC004051.2. Does perturbing FOXO4 lead to a significant change in AC004051.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1841
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RP5-1142A6.2. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RP5-1142A6.2. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4714
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and MME expression is observed. Does this perturbation lead to a significant difference in MME expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and MME expression is observed. Does this perturbation lead to a significant difference in MME expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6263
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2962
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01395 expression. Decide whether this perturbation leads to a significant alteration in LINC01395 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor LINC01395 expression. Decide whether this perturbation leads to a significant alteration in LINC01395 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5598
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD47 expression is quantified. Does this perturbation result in a significant change in CD47 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD47 expression is quantified. Does this perturbation result in a significant change in CD47 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":782
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of THBS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3217
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of TAPBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of TAPBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2237
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3378
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Does this perturbation cause a significant change in MOGAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Does this perturbation cause a significant change in MOGAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5530
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1927
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is quantified. Does this perturbation result in a significant change in RPL17-C18orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is quantified. Does this perturbation result in a significant change in RPL17-C18orf32 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5772
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SLC22A25 expression is quantified. Does this perturbation result in a significant change in SLC22A25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SLC22A25 expression is quantified. Does this perturbation result in a significant change in SLC22A25 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1832
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of H1FNT. Does perturbing C19orf26 lead to a significant change in H1FNT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of H1FNT. Does perturbing C19orf26 lead to a significant change in H1FNT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2911
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Does this perturbation cause a significant change in LEFTY1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Does this perturbation cause a significant change in LEFTY1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5910
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Does this perturbation cause a significant change in HIST1H2AC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3180
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and RP11-195C7.1 expression is quantified. Does this perturbation result in a significant change in RP11-195C7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and RP11-195C7.1 expression is quantified. Does this perturbation result in a significant change in RP11-195C7.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1732
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and SLC31A2 expression is quantified. Does this perturbation result in a significant change in SLC31A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and SLC31A2 expression is quantified. Does this perturbation result in a significant change in SLC31A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5412
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6179
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CD46 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4205
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3719
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is quantified. Does this perturbation result in a significant change in RHOXF2BB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is quantified. Does this perturbation result in a significant change in RHOXF2BB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5712
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-290K4.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-290K4.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3707
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Does this perturbation cause a significant change in PHACTR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Does this perturbation cause a significant change in PHACTR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4380
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CKS2 expression. Decide whether this perturbation leads to a significant alteration in CKS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CKS2 expression. Decide whether this perturbation leads to a significant alteration in CKS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2078
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3914
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CTD-3131K8.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CTD-3131K8.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2757
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3302
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Determine whether CTSS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of CTSS is measured. Determine whether CTSS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2026
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZEB2. Does this perturbation cause a significant change in ZEB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3204
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of HEATR9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of HEATR9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2387
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CD37 expression is observed. Does this perturbation lead to a significant difference in CD37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CD37 expression is observed. Does this perturbation lead to a significant difference in CD37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3243
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Determine whether DST shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2346
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":62
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in FOXL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3685
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is quantified. Does this perturbation result in a significant change in RP11-662J14.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is quantified. Does this perturbation result in a significant change in RP11-662J14.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5242
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1012
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Does this perturbation cause a significant change in C19orf38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Does this perturbation cause a significant change in C19orf38 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4840
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and TXNIP expression is measured. Determine whether TXNIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4699
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Determine whether H1FNT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Determine whether H1FNT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2916
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1473
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of C1orf162 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of C1orf162 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3537
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SLC22A25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SLC22A25 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1835
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4109
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CD59. Does perturbing CDKN1A lead to a significant change in CD59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CD59. Does perturbing CDKN1A lead to a significant change in CD59 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2371
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and RP11-195C7.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195C7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and RP11-195C7.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195C7.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1733
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and TEX30 expression is measured. Determine whether TEX30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and TEX30 expression is measured. Determine whether TEX30 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2419
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of SCG5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of SCG5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5857
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Determine whether DLX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Determine whether DLX4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6166
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-290K4.2. Does this perturbation cause a significant change in RP11-290K4.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-290K4.2. Does this perturbation cause a significant change in RP11-290K4.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3704
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4974
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and CTB-49A3.5 expression is observed. Does this perturbation lead to a significant difference in CTB-49A3.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and CTB-49A3.5 expression is observed. Does this perturbation lead to a significant difference in CTB-49A3.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3393
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of NCF4. Does perturbing SET lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of NCF4. Does perturbing SET lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":851
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Does this perturbation cause a significant change in HIPK1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Does this perturbation cause a significant change in HIPK1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3220
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SLC2A1-AS1. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SLC2A1-AS1. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1994
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and COL1A1 expression is observed. Does this perturbation lead to a significant difference in COL1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and COL1A1 expression is observed. Does this perturbation lead to a significant difference in COL1A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5053
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ETS1 expression is observed. Does this perturbation lead to a significant difference in ETS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and ETS1 expression is observed. Does this perturbation lead to a significant difference in ETS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":583
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5514
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and C1orf141 expression is measured. Determine whether C1orf141 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and C1orf141 expression is measured. Determine whether C1orf141 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2339
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1727
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of SLC7A11. Does perturbing NCL lead to a significant change in SLC7A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of SLC7A11. Does perturbing NCL lead to a significant change in SLC7A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4891
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SOCS2 expression is observed. Does this perturbation lead to a significant difference in SOCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SOCS2 expression is observed. Does this perturbation lead to a significant difference in SOCS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":693
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and SLC43A2 expression is quantified. Does this perturbation result in a significant change in SLC43A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and SLC43A2 expression is quantified. Does this perturbation result in a significant change in SLC43A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1532
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor ACE expression. Decide whether this perturbation leads to a significant alteration in ACE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3658
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Determine whether TMEM154 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Determine whether TMEM154 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4146
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of RP11-445F12.1. Does perturbing BAK1 lead to a significant change in RP11-445F12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of RP11-445F12.1. Does perturbing BAK1 lead to a significant change in RP11-445F12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":601
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4869
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and FAM46C expression is observed. Does this perturbation lead to a significant difference in FAM46C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and FAM46C expression is observed. Does this perturbation lead to a significant difference in FAM46C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2893
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PPFIA4 expression is quantified. Does this perturbation result in a significant change in PPFIA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and PPFIA4 expression is quantified. Does this perturbation result in a significant change in PPFIA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5302
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4154
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in PERM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in PERM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5485
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of APOBR. Does perturbing STIL lead to a significant change in APOBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of APOBR. Does perturbing STIL lead to a significant change in APOBR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5171
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of VASH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of VASH1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3357
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ACE. Does perturbing PRTG lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ACE. Does perturbing PRTG lead to a significant change in ACE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3651
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Determine whether CTD-2012K14.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CTD-2012K14.6 is measured. Determine whether CTD-2012K14.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5216
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and LINC01338 expression is measured. Determine whether LINC01338 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and LINC01338 expression is measured. Determine whether LINC01338 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5079
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of PGA4. Does this perturbation cause a significant change in PGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of PGA4. Does this perturbation cause a significant change in PGA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6034
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and S100A1 expression is quantified. Does this perturbation result in a significant change in S100A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and S100A1 expression is quantified. Does this perturbation result in a significant change in S100A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1752
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of UNC5B. Does perturbing CLDN6 lead to a significant change in UNC5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of UNC5B. Does perturbing CLDN6 lead to a significant change in UNC5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3251
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3876
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and RLN3 expression is quantified. Does this perturbation result in a significant change in RLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and RLN3 expression is quantified. Does this perturbation result in a significant change in RLN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5002
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1269
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Does this perturbation cause a significant change in TCAF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Does this perturbation cause a significant change in TCAF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2970
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Determine whether KRTAP9-9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Determine whether KRTAP9-9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5296
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA5. Does perturbing MAPK1 lead to a significant change in ANXA5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA5. Does perturbing MAPK1 lead to a significant change in ANXA5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2851
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of S100A4. Does this perturbation cause a significant change in S100A4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of S100A4. Does this perturbation cause a significant change in S100A4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1044
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4320
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of AMPH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of AMPH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6017
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in N4BP2L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in N4BP2L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4225
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of MMP19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of MMP19 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":947
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Does this perturbation cause a significant change in PSMB8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Does this perturbation cause a significant change in PSMB8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":100
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in RHOXF2BB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in RHOXF2BB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5715
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Determine whether CCNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Determine whether CCNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3856
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Determine whether BMP2K shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of BMP2K is measured. Determine whether BMP2K shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1506
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and EGOT expression is quantified. Does this perturbation result in a significant change in EGOT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and EGOT expression is quantified. Does this perturbation result in a significant change in EGOT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5672
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4102
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of TCAF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of TCAF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2977
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RP11-285F7.2. Does perturbing NCL lead to a significant change in RP11-285F7.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of RP11-285F7.2. Does perturbing NCL lead to a significant change in RP11-285F7.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4901
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RP11-308D13.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-308D13.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor RP11-308D13.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-308D13.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":768
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of RP11-442O1.4. Does this perturbation cause a significant change in RP11-442O1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of RP11-442O1.4. Does this perturbation cause a significant change in RP11-442O1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4664
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNDC3B. Does perturbing FOSB lead to a significant change in RUNDC3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNDC3B. Does perturbing FOSB lead to a significant change in RUNDC3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2801
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Determine whether CD37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CD37 is measured. Determine whether CD37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3246
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Determine whether GPR157 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of GPR157 is measured. Determine whether GPR157 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3056
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":970
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Does this perturbation cause a significant change in POC1B-GALNT4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1970
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of RETN. Does this perturbation cause a significant change in RETN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of RETN. Does this perturbation cause a significant change in RETN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2454
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLA2G1B expression is measured. Determine whether PLA2G1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLA2G1B expression is measured. Determine whether PLA2G1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":759
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and HSD17B4 expression is measured. Determine whether HSD17B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and HSD17B4 expression is measured. Determine whether HSD17B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":149
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of IFIT2. Does this perturbation cause a significant change in IFIT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of IFIT2. Does this perturbation cause a significant change in IFIT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6024
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1564
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and TLN1 expression is observed. Does this perturbation lead to a significant difference in TLN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1523
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and SLC22A11 expression is measured. Determine whether SLC22A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and SLC22A11 expression is measured. Determine whether SLC22A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4309
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CYP1B1-AS1. Does perturbing HNF4A lead to a significant change in CYP1B1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CYP1B1-AS1. Does perturbing HNF4A lead to a significant change in CYP1B1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4311
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":373
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TUBA1A. Does this perturbation cause a significant change in TUBA1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TUBA1A. Does this perturbation cause a significant change in TUBA1A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2714
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in MYL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in MYL4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5565
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-109E24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-109E24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6217
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Determine whether LINC01395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Determine whether LINC01395 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5596
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Determine whether RP11-202A13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Determine whether RP11-202A13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4786
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":914
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in PHGDH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4505
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is measured. Determine whether CACNA1C-AS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is measured. Determine whether CACNA1C-AS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":359
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in RPS6KA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in RPS6KA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1605
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2052
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Determine whether TMEM55A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Determine whether TMEM55A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4606
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ANXA3 expression is measured. Determine whether ANXA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ANXA3 expression is measured. Determine whether ANXA3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3969
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of H1FNT. Does this perturbation cause a significant change in H1FNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of H1FNT. Does this perturbation cause a significant change in H1FNT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2914
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Does this perturbation cause a significant change in PYROXD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2220
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of HBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of HBE1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":447
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5045
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4166
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Determine whether PTRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Determine whether PTRF shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1036
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Does this perturbation cause a significant change in RUNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Does this perturbation cause a significant change in RUNX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5950
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Does this perturbation cause a significant change in ICAM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Does this perturbation cause a significant change in ICAM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4740
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP11-345P4.7. Does perturbing MAPK1 lead to a significant change in RP11-345P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP11-345P4.7. Does perturbing MAPK1 lead to a significant change in RP11-345P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2871
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2544
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CCDC159. Does perturbing CEBPA lead to a significant change in CCDC159 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CCDC159. Does perturbing CEBPA lead to a significant change in CCDC159 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4251
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PTRF expression is quantified. Does this perturbation result in a significant change in PTRF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PTRF expression is quantified. Does this perturbation result in a significant change in PTRF expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1032
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of TOX. Does perturbing MAP4K5 lead to a significant change in TOX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of TOX. Does perturbing MAP4K5 lead to a significant change in TOX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1361
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5169
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6240
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of TRPM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of TRPM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1427
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and SEMA3B expression is quantified. Does this perturbation result in a significant change in SEMA3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and SEMA3B expression is quantified. Does this perturbation result in a significant change in SEMA3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4242
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of COL21A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of COL21A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4427
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2462
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Determine whether FNDC3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of FNDC3A is measured. Determine whether FNDC3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4586
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and HSD17B4 expression is observed. Does this perturbation lead to a significant difference in HSD17B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and HSD17B4 expression is observed. Does this perturbation lead to a significant difference in HSD17B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":143
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and STRC expression is observed. Does this perturbation lead to a significant difference in STRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and STRC expression is observed. Does this perturbation lead to a significant difference in STRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5903
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ZNF610 expression is observed. Does this perturbation lead to a significant difference in ZNF610 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and ZNF610 expression is observed. Does this perturbation lead to a significant difference in ZNF610 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2433
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6059
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of IL1RN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of IL1RN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2197
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and HBE1 expression is observed. Does this perturbation lead to a significant difference in HBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and HBE1 expression is observed. Does this perturbation lead to a significant difference in HBE1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":443
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4489
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and UBE2H expression is measured. Determine whether UBE2H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5519
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and MYL4 expression is measured. Determine whether MYL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and MYL4 expression is measured. Determine whether MYL4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5569
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4816
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in DRC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in DRC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5665
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and IFIT2 expression is observed. Does this perturbation lead to a significant difference in IFIT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and IFIT2 expression is observed. Does this perturbation lead to a significant difference in IFIT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6023
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of SOX5. Does this perturbation cause a significant change in SOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of SOX5. Does this perturbation cause a significant change in SOX5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2474
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of CD52. Does perturbing MAML2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of CD52. Does perturbing MAML2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":81
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor RP1-59D14.10 expression. Decide whether this perturbation leads to a significant alteration in RP1-59D14.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor RP1-59D14.10 expression. Decide whether this perturbation leads to a significant alteration in RP1-59D14.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3778
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and TNFRSF12A expression is quantified. Does this perturbation result in a significant change in TNFRSF12A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and TNFRSF12A expression is quantified. Does this perturbation result in a significant change in TNFRSF12A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3902
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1462
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Determine whether HERPUD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5826
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor RP11-968A15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-968A15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor RP11-968A15.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-968A15.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":838
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and TNFAIP8 expression is measured. Determine whether TNFAIP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and TNFAIP8 expression is measured. Determine whether TNFAIP8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2189
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is quantified. Does this perturbation result in a significant change in RP11-510J16.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is quantified. Does this perturbation result in a significant change in RP11-510J16.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1062
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":240
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of SLC7A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of SLC7A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4897
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of RGS16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":217
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor HERPUD1 expression. Decide whether this perturbation leads to a significant alteration in HERPUD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5828
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ARHGEF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of ARHGEF6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2117
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CYP1B1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP1B1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CYP1B1-AS1 expression. Decide whether this perturbation leads to a significant alteration in CYP1B1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4318
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2702
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RP4-550H1.4 expression is observed. Does this perturbation lead to a significant difference in RP4-550H1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RP4-550H1.4 expression is observed. Does this perturbation lead to a significant difference in RP4-550H1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5793
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZEB2 expression is quantified. Does this perturbation result in a significant change in ZEB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3202
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and CCDC136 expression is measured. Determine whether CCDC136 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and CCDC136 expression is measured. Determine whether CCDC136 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5039
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Does this perturbation cause a significant change in SLC20A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Does this perturbation cause a significant change in SLC20A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2400
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor TLCD2 expression. Decide whether this perturbation leads to a significant alteration in TLCD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor TLCD2 expression. Decide whether this perturbation leads to a significant alteration in TLCD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5558
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of NCALD. Does this perturbation cause a significant change in NCALD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of NCALD. Does this perturbation cause a significant change in NCALD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4834
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and TAS1R1 expression is measured. Determine whether TAS1R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and TAS1R1 expression is measured. Determine whether TAS1R1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":709
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in APOL6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in APOL6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3425
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in SH3BGRL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in SH3BGRL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":395
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in FMNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in FMNL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1695
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1476
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in CTC-490E21.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in CTC-490E21.10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":575
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of INHBE. Does this perturbation cause a significant change in INHBE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of INHBE. Does this perturbation cause a significant change in INHBE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5784
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of PKIG. Does perturbing DUSP9 lead to a significant change in PKIG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of PKIG. Does perturbing DUSP9 lead to a significant change in PKIG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":201
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of HBD. Does perturbing UBASH3A lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of HBD. Does perturbing UBASH3A lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4811
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Determine whether EGOT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Determine whether EGOT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5676
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1955
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of TOR3A. Does perturbing NIT1 lead to a significant change in TOR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of TOR3A. Does perturbing NIT1 lead to a significant change in TOR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5341
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5812
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Does this perturbation cause a significant change in TNFAIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of TNFAIP2 is measured. Does this perturbation cause a significant change in TNFAIP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5200
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor CD24 expression. Decide whether this perturbation leads to a significant alteration in CD24 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3578
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Determine whether TSC22D4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":196
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Determine whether AK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Determine whether AK8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4396
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and AMPH expression is quantified. Does this perturbation result in a significant change in AMPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and AMPH expression is quantified. Does this perturbation result in a significant change in AMPH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6012
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and TNFRSF12A expression is measured. Determine whether TNFRSF12A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and TNFRSF12A expression is measured. Determine whether TNFRSF12A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3909
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2965
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1922
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5510
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MS4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MS4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":987
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and TUBB expression is observed. Does this perturbation lead to a significant difference in TUBB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and TUBB expression is observed. Does this perturbation lead to a significant difference in TUBB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2643
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Does this perturbation cause a significant change in TLCD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Does this perturbation cause a significant change in TLCD2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5550
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and CNN2 expression is quantified. Does this perturbation result in a significant change in CNN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and CNN2 expression is quantified. Does this perturbation result in a significant change in CNN2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4702
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":122
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and RP11-38J22.3 expression is quantified. Does this perturbation result in a significant change in RP11-38J22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and RP11-38J22.3 expression is quantified. Does this perturbation result in a significant change in RP11-38J22.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6072
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of NBR1. Does this perturbation cause a significant change in NBR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4274
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and THBS1 expression is observed. Does this perturbation lead to a significant difference in THBS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3213
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TPP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1575
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Determine whether TAS2R9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of TAS2R9 is measured. Determine whether TAS2R9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":896
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and MYO1F expression is quantified. Does this perturbation result in a significant change in MYO1F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and MYO1F expression is quantified. Does this perturbation result in a significant change in MYO1F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1512
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3916
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of TOR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of TOR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5347
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":550
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of PPP4R4. Does this perturbation cause a significant change in PPP4R4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of PPP4R4. Does this perturbation cause a significant change in PPP4R4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4614
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2227
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of POC1B-GALNT4. Does perturbing RUNX1T1 lead to a significant change in POC1B-GALNT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of POC1B-GALNT4. Does perturbing RUNX1T1 lead to a significant change in POC1B-GALNT4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1971
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of WBP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1657
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Determine whether AC020571.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Determine whether AC020571.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1216
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor SLC31A2 expression. Decide whether this perturbation leads to a significant alteration in SLC31A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor SLC31A2 expression. Decide whether this perturbation leads to a significant alteration in SLC31A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5418
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5765
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of SH3BGRL. Does perturbing BCORL1 lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of SH3BGRL. Does perturbing BCORL1 lead to a significant change in SH3BGRL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":391
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLEKHO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLEKHO1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6127
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-497G19.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-497G19.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1255
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6134
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Determine whether FEZ1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3566
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in KRTAP9-9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in KRTAP9-9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5295
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor COLGALT2 expression. Decide whether this perturbation leads to a significant alteration in COLGALT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4098
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor SLC7A11 expression. Decide whether this perturbation leads to a significant alteration in SLC7A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor SLC7A11 expression. Decide whether this perturbation leads to a significant alteration in SLC7A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4898
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ASIC4. Does perturbing MAP2K3 lead to a significant change in ASIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of ASIC4. Does perturbing MAP2K3 lead to a significant change in ASIC4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2241
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is quantified. Does this perturbation result in a significant change in RP11-369K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is quantified. Does this perturbation result in a significant change in RP11-369K17.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5472
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Determine whether CEBPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Determine whether CEBPD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6066
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1565
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and PROX1 expression is quantified. Does this perturbation result in a significant change in PROX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and PROX1 expression is quantified. Does this perturbation result in a significant change in PROX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4052
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1326
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4750
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and FAM225B expression is quantified. Does this perturbation result in a significant change in FAM225B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and FAM225B expression is quantified. Does this perturbation result in a significant change in FAM225B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5232
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in HOXB6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in HOXB6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":815
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Does this perturbation cause a significant change in RUNDC3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Does this perturbation cause a significant change in RUNDC3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2800
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of FLJ12825. Does perturbing CEBPE lead to a significant change in FLJ12825 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of FLJ12825. Does perturbing CEBPE lead to a significant change in FLJ12825 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":171
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C6orf1 expression. Decide whether this perturbation leads to a significant alteration in C6orf1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C6orf1 expression. Decide whether this perturbation leads to a significant alteration in C6orf1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1878
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of MAOB. Does this perturbation cause a significant change in MAOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of MAOB. Does this perturbation cause a significant change in MAOB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1494
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4752
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1614
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of AC139099.6. Does this perturbation cause a significant change in AC139099.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of AC139099.6. Does this perturbation cause a significant change in AC139099.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3474
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Does this perturbation cause a significant change in CYP3A5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Does this perturbation cause a significant change in CYP3A5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":860
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Determine whether SLC43A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Determine whether SLC43A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1536
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5042
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RP11-83A24.2. Does this perturbation cause a significant change in RP11-83A24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RP11-83A24.2. Does this perturbation cause a significant change in RP11-83A24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":524
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3000
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":929
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and SOX4 expression is quantified. Does this perturbation result in a significant change in SOX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2352
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ITGA3 expression. Decide whether this perturbation leads to a significant alteration in ITGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor ITGA3 expression. Decide whether this perturbation leads to a significant alteration in ITGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4138
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and SP6 expression is measured. Determine whether SP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and SP6 expression is measured. Determine whether SP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1709
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of LEFTY1. Does this perturbation cause a significant change in LEFTY1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of LEFTY1. Does this perturbation cause a significant change in LEFTY1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5914
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM83F. Does this perturbation cause a significant change in FAM83F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM83F. Does this perturbation cause a significant change in FAM83F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2684
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of TNFRSF12A. Does perturbing LYL1 lead to a significant change in TNFRSF12A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of TNFRSF12A. Does perturbing LYL1 lead to a significant change in TNFRSF12A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3901
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3875
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Does this perturbation cause a significant change in CBL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Does this perturbation cause a significant change in CBL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3140
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of CEBPA. Does perturbing CBFA2T3 lead to a significant change in CEBPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of CEBPA. Does perturbing CBFA2T3 lead to a significant change in CEBPA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1631
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Determine whether CTB-49A3.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Determine whether CTB-49A3.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3396
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3199
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":569
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and PYROXD2 expression is observed. Does this perturbation lead to a significant difference in PYROXD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5153
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of AC139099.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of AC139099.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3477
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Determine whether LRRTM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Determine whether LRRTM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5846
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and TNFAIP8 expression is observed. Does this perturbation lead to a significant difference in TNFAIP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and TNFAIP8 expression is observed. Does this perturbation lead to a significant difference in TNFAIP8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2183
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and AC004051.2 expression is observed. Does this perturbation lead to a significant difference in AC004051.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and AC004051.2 expression is observed. Does this perturbation lead to a significant difference in AC004051.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1843
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1390
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor DEK expression. Decide whether this perturbation leads to a significant alteration in DEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor DEK expression. Decide whether this perturbation leads to a significant alteration in DEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1678
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3783
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3506
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of IL20. Does this perturbation cause a significant change in IL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of IL20. Does this perturbation cause a significant change in IL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3764
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of MSRB1 is measured. Does this perturbation cause a significant change in MSRB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2650
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and SOCS1 expression is quantified. Does this perturbation result in a significant change in SOCS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4082
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and BMP2K expression is measured. Determine whether BMP2K exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and BMP2K expression is measured. Determine whether BMP2K exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1509
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":23
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is measured. Determine whether RP11-646I6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is measured. Determine whether RP11-646I6.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1079
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in HERPUD1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5825
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3735
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-109E24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-109E24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-109E24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-109E24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6213
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and PRTN3 expression is quantified. Does this perturbation result in a significant change in PRTN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and PRTN3 expression is quantified. Does this perturbation result in a significant change in PRTN3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1102
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of AC004540.4. Does this perturbation cause a significant change in AC004540.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of AC004540.4. Does this perturbation cause a significant change in AC004540.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4124
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Does this perturbation cause a significant change in CD46 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4200
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD47 expression is observed. Does this perturbation lead to a significant difference in CD47 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":783
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Determine whether AC139099.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Determine whether AC139099.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3476
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor TACC1 expression. Decide whether this perturbation leads to a significant alteration in TACC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor TACC1 expression. Decide whether this perturbation leads to a significant alteration in TACC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6008
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LGALS1 expression. Decide whether this perturbation leads to a significant alteration in LGALS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5818
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of C19orf38. Does perturbing UBASH3A lead to a significant change in C19orf38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of C19orf38. Does perturbing UBASH3A lead to a significant change in C19orf38 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4841
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of LHX1. Does perturbing BAK1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of LHX1. Does perturbing BAK1 lead to a significant change in LHX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":611
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":245
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-646I6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-646I6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-646I6.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-646I6.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1078
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5273
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Does this perturbation cause a significant change in PAMR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Does this perturbation cause a significant change in PAMR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4790
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Determine whether NUDC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Determine whether NUDC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2156
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor XK expression. Decide whether this perturbation leads to a significant alteration in XK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor XK expression. Decide whether this perturbation leads to a significant alteration in XK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2628
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of MOGAT2. Does this perturbation cause a significant change in MOGAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of MOGAT2. Does this perturbation cause a significant change in MOGAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5534
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of LPAR2. Does perturbing HOXB9 lead to a significant change in LPAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of LPAR2. Does perturbing HOXB9 lead to a significant change in LPAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3101
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in HMGA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in HMGA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3895
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6170
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Determine whether EMP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Determine whether EMP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3036
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5837
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and FBXL20 expression is quantified. Does this perturbation result in a significant change in FBXL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5762
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and COTL1 expression is observed. Does this perturbation lead to a significant difference in COTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and COTL1 expression is observed. Does this perturbation lead to a significant difference in COTL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1283
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor RP11-635N19.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-635N19.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor RP11-635N19.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-635N19.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1378
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of CBL. Does this perturbation cause a significant change in CBL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of CBL. Does this perturbation cause a significant change in CBL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3144
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and RLN3 expression is observed. Does this perturbation lead to a significant difference in RLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and RLN3 expression is observed. Does this perturbation lead to a significant difference in RLN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5003
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor HIST1H3H expression. Decide whether this perturbation leads to a significant alteration in HIST1H3H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor HIST1H3H expression. Decide whether this perturbation leads to a significant alteration in HIST1H3H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5338
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3434
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of VASH1. Does perturbing FOXA3 lead to a significant change in VASH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of VASH1. Does perturbing FOXA3 lead to a significant change in VASH1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3351
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SPANXN5 expression is measured. Determine whether SPANXN5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SPANXN5 expression is measured. Determine whether SPANXN5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3469
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3572
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of REEP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of REEP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2007
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of FNDC3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of FNDC3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4587
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of RP11-180M15.6. Does perturbing IGDCC3 lead to a significant change in RP11-180M15.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of RP11-180M15.6. Does perturbing IGDCC3 lead to a significant change in RP11-180M15.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4431
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-567N4.3. Does this perturbation cause a significant change in RP11-567N4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-567N4.3. Does this perturbation cause a significant change in RP11-567N4.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1784
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Determine whether AC007193.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Determine whether AC007193.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2636
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and ZNF431 expression is measured. Determine whether ZNF431 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4679
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01395 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01395 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5597
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and GIPC2 expression is observed. Does this perturbation lead to a significant difference in GIPC2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4483
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4684
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Does this perturbation cause a significant change in GIPR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Does this perturbation cause a significant change in GIPR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5350
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM83F expression is measured. Determine whether FAM83F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM83F expression is measured. Determine whether FAM83F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2689
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":850
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and UNC5B expression is quantified. Does this perturbation result in a significant change in UNC5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and UNC5B expression is quantified. Does this perturbation result in a significant change in UNC5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3252
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5264
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CACNA1C-AS2 expression is observed. Does this perturbation lead to a significant difference in CACNA1C-AS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CACNA1C-AS2 expression is observed. Does this perturbation lead to a significant difference in CACNA1C-AS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":353
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of KIF2C is measured. Does this perturbation cause a significant change in KIF2C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4560
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of RP11-714G18.1. Does this perturbation cause a significant change in RP11-714G18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of RP11-714G18.1. Does this perturbation cause a significant change in RP11-714G18.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1854
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of HBD. Does this perturbation cause a significant change in HBD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4814
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and LINC00479 expression is measured. Determine whether LINC00479 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and LINC00479 expression is measured. Determine whether LINC00479 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":419
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Does this perturbation cause a significant change in RP11-497G19.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Does this perturbation cause a significant change in RP11-497G19.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1250
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and SP6 expression is quantified. Does this perturbation result in a significant change in SP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and SP6 expression is quantified. Does this perturbation result in a significant change in SP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1702
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Does this perturbation cause a significant change in AC020571.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of AC020571.3 is measured. Does this perturbation cause a significant change in AC020571.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1210
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":56
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of CSRNP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of CSRNP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4647
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ZMYND15 expression is measured. Determine whether ZMYND15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and ZMYND15 expression is measured. Determine whether ZMYND15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2739
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of PRTN3. Does this perturbation cause a significant change in PRTN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of PRTN3. Does this perturbation cause a significant change in PRTN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1104
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5507
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CCNB1. Does this perturbation cause a significant change in CCNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CCNB1. Does this perturbation cause a significant change in CCNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3854
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and MYL4 expression is quantified. Does this perturbation result in a significant change in MYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and MYL4 expression is quantified. Does this perturbation result in a significant change in MYL4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5562
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of RP11-1085N6.3. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of RP11-1085N6.3. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3404
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor TAS2R9 expression. Decide whether this perturbation leads to a significant alteration in TAS2R9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor TAS2R9 expression. Decide whether this perturbation leads to a significant alteration in TAS2R9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":898
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3793
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Determine whether RUNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RUNX3 is measured. Determine whether RUNX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5956
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of FAM49A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of FAM49A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":477
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of AK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of AK8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4397
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":67
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5109
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and FOXF1 expression is quantified. Does this perturbation result in a significant change in FOXF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3492
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of RP1-261G23.7. Does perturbing RHOXF2BB lead to a significant change in RP1-261G23.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of RP1-261G23.7. Does perturbing RHOXF2BB lead to a significant change in RP1-261G23.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1901
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and MYLIP expression is quantified. Does this perturbation result in a significant change in MYLIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and MYLIP expression is quantified. Does this perturbation result in a significant change in MYLIP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1232
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ITGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in ITGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4135
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of TAS1R1. Does perturbing FEV lead to a significant change in TAS1R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of TAS1R1. Does perturbing FEV lead to a significant change in TAS1R1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":701
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and RP11-195B3.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195B3.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and RP11-195B3.1 expression is observed. Does this perturbation lead to a significant difference in RP11-195B3.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2213
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of TAPBP. Does this perturbation cause a significant change in TAPBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of TAPBP. Does this perturbation cause a significant change in TAPBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2234
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of FABP3. Does perturbing BPGM lead to a significant change in FABP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of FABP3. Does perturbing BPGM lead to a significant change in FABP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3721
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4237
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and CTSS expression is measured. Determine whether CTSS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and CTSS expression is measured. Determine whether CTSS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2029
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Determine whether FMNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Determine whether FMNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1696
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CRYM. Does perturbing C3orf72 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CRYM. Does perturbing C3orf72 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3841
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in FILIP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in FILIP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2265
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of S100A1. Does perturbing AHR lead to a significant change in S100A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of S100A1. Does perturbing AHR lead to a significant change in S100A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1751
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4882
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and FZD6 expression is observed. Does this perturbation lead to a significant difference in FZD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and FZD6 expression is observed. Does this perturbation lead to a significant difference in FZD6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2993
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Does this perturbation cause a significant change in RP11-308D13.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Does this perturbation cause a significant change in RP11-308D13.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":760
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5643
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":998
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Does this perturbation cause a significant change in HBE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of HBE1 is measured. Does this perturbation cause a significant change in HBE1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":440
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-328J14.1. Does this perturbation cause a significant change in RP11-328J14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-328J14.1. Does this perturbation cause a significant change in RP11-328J14.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2574
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Determine whether SPANXD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Determine whether SPANXD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4196
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2963
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor CCNG2 expression. Decide whether this perturbation leads to a significant alteration in CCNG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4068
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PPFIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PPFIA4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5305
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1398
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and UCKL1-AS1 expression is observed. Does this perturbation lead to a significant difference in UCKL1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and UCKL1-AS1 expression is observed. Does this perturbation lead to a significant difference in UCKL1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5253
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ACP5 expression. Decide whether this perturbation leads to a significant alteration in ACP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor ACP5 expression. Decide whether this perturbation leads to a significant alteration in ACP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1208
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of PERM1. Does this perturbation cause a significant change in PERM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of PERM1. Does this perturbation cause a significant change in PERM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5484
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in KRT79 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in KRT79 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3885
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ATG2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ATG2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3635
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3717
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and HOXB6 expression is quantified. Does this perturbation result in a significant change in HOXB6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and HOXB6 expression is quantified. Does this perturbation result in a significant change in HOXB6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":812
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of BAK1. Does perturbing BAK1 lead to a significant change in BAK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":621
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CD59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CD59 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2377
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2058
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is measured. Determine whether RP1-261G23.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is measured. Determine whether RP1-261G23.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1909
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CPXM1 expression is observed. Does this perturbation lead to a significant difference in CPXM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CPXM1 expression is observed. Does this perturbation lead to a significant difference in CPXM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":383
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ACSL1 expression is quantified. Does this perturbation result in a significant change in ACSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and ACSL1 expression is quantified. Does this perturbation result in a significant change in ACSL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2772
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and KCNQ1-AS1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and KCNQ1-AS1 expression is observed. Does this perturbation lead to a significant difference in KCNQ1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5113
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and CCNB2 expression is quantified. Does this perturbation result in a significant change in CCNB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and CCNB2 expression is quantified. Does this perturbation result in a significant change in CCNB2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4332
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Does this perturbation cause a significant change in DRC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Does this perturbation cause a significant change in DRC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5660
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Determine whether TNNI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1726
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and C19orf38 expression is quantified. Does this perturbation result in a significant change in C19orf38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and C19orf38 expression is quantified. Does this perturbation result in a significant change in C19orf38 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4842
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3877
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of DST. Does perturbing CDKN1A lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of DST. Does perturbing CDKN1A lead to a significant change in DST expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2341
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Does this perturbation cause a significant change in SLC31A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Does this perturbation cause a significant change in SLC31A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5410
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3848
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in CBL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3145
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and CAPG expression is measured. Determine whether CAPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and CAPG expression is measured. Determine whether CAPG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4879
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Does this perturbation cause a significant change in RP4-565E6.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Does this perturbation cause a significant change in RP4-565E6.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":290
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor TTC9B expression. Decide whether this perturbation leads to a significant alteration in TTC9B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor TTC9B expression. Decide whether this perturbation leads to a significant alteration in TTC9B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4498
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of HIST1H3H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of HIST1H3H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5337
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of RP11-537H15.3. Does this perturbation cause a significant change in RP11-537H15.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of RP11-537H15.3. Does this perturbation cause a significant change in RP11-537H15.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2274
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CIB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5227
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SLC22A25 expression is observed. Does this perturbation lead to a significant difference in SLC22A25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SLC22A25 expression is observed. Does this perturbation lead to a significant difference in SLC22A25 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1833
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":78
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Determine whether GRAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Determine whether GRAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":316
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of RABAC1. Does this perturbation cause a significant change in RABAC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of RABAC1. Does this perturbation cause a significant change in RABAC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5144
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Does this perturbation cause a significant change in HEATR9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Does this perturbation cause a significant change in HEATR9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2380
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-128B16.3. Does this perturbation cause a significant change in RP11-128B16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-128B16.3. Does this perturbation cause a significant change in RP11-128B16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1794
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1147
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5833
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and FZD6 expression is quantified. Does this perturbation result in a significant change in FZD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and FZD6 expression is quantified. Does this perturbation result in a significant change in FZD6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2992
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1187
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in XK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in XK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2625
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01395 expression is quantified. Does this perturbation result in a significant change in LINC01395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01395 expression is quantified. Does this perturbation result in a significant change in LINC01395 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5592
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and PERM1 expression is observed. Does this perturbation lead to a significant difference in PERM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and PERM1 expression is observed. Does this perturbation lead to a significant difference in PERM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5483
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3082
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2056
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ADD3 expression is measured. Determine whether ADD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ADD3 expression is measured. Determine whether ADD3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2909
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5926
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":495
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNDC3B expression. Decide whether this perturbation leads to a significant alteration in RUNDC3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor RUNDC3B expression. Decide whether this perturbation leads to a significant alteration in RUNDC3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2808
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3150
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and VASH1 expression is measured. Determine whether VASH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and VASH1 expression is measured. Determine whether VASH1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3359
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and DEK expression is quantified. Does this perturbation result in a significant change in DEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and DEK expression is quantified. Does this perturbation result in a significant change in DEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1672
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNDC3B expression is measured. Determine whether RUNDC3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNDC3B expression is measured. Determine whether RUNDC3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2809
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RP5-1142A6.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RP5-1142A6.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4715
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SLC22A25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SLC22A25 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1837
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5749
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in H1FNT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in H1FNT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2915
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Determine whether CTD-2378E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Determine whether CTD-2378E12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6276
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and GPR35 expression is observed. Does this perturbation lead to a significant difference in GPR35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and GPR35 expression is observed. Does this perturbation lead to a significant difference in GPR35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3923
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4822
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and FAM19A2 expression is measured. Determine whether FAM19A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and FAM19A2 expression is measured. Determine whether FAM19A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3369
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and RP11-537H15.3 expression is observed. Does this perturbation lead to a significant difference in RP11-537H15.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and RP11-537H15.3 expression is observed. Does this perturbation lead to a significant difference in RP11-537H15.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2273
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ARL6IP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2935
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5646
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of LGALS12. Does perturbing DUSP9 lead to a significant change in LGALS12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of LGALS12. Does perturbing DUSP9 lead to a significant change in LGALS12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":181
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3290
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of TLCD2. Does this perturbation cause a significant change in TLCD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of TLCD2. Does this perturbation cause a significant change in TLCD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5554
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2844
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Determine whether N4BP2L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Determine whether N4BP2L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4226
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ADD3 expression is quantified. Does this perturbation result in a significant change in ADD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ADD3 expression is quantified. Does this perturbation result in a significant change in ADD3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2902
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RP11-308D13.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RP11-308D13.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":765
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LRP10 expression. Decide whether this perturbation leads to a significant alteration in LRP10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LRP10 expression. Decide whether this perturbation leads to a significant alteration in LRP10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3318
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of MT1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of MT1E indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":367
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor AC139099.6 expression. Decide whether this perturbation leads to a significant alteration in AC139099.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor AC139099.6 expression. Decide whether this perturbation leads to a significant alteration in AC139099.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3478
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Determine whether LGALS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4636
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of SSTR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of SSTR3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3177
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":487
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ZIC4 expression is observed. Does this perturbation lead to a significant difference in ZIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and ZIC4 expression is observed. Does this perturbation lead to a significant difference in ZIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2613
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in CEBPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in CEBPA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1635
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and INHBE expression is quantified. Does this perturbation result in a significant change in INHBE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and INHBE expression is quantified. Does this perturbation result in a significant change in INHBE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5782
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNDC3B expression is observed. Does this perturbation lead to a significant difference in RUNDC3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNDC3B expression is observed. Does this perturbation lead to a significant difference in RUNDC3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2803
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CACNA1C-AS2. Does perturbing FOXA1 lead to a significant change in CACNA1C-AS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of CACNA1C-AS2. Does perturbing FOXA1 lead to a significant change in CACNA1C-AS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":351
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Determine whether PHACTR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of PHACTR1 is measured. Determine whether PHACTR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4386
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ATP8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ATP8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3527
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CITED2. Does perturbing HNF4A lead to a significant change in CITED2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of CITED2. Does perturbing HNF4A lead to a significant change in CITED2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4281
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Does this perturbation cause a significant change in CCNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Does this perturbation cause a significant change in CCNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6140
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1480
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CTD-2311M21.3. Does perturbing BCORL1 lead to a significant change in CTD-2311M21.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CTD-2311M21.3. Does perturbing BCORL1 lead to a significant change in CTD-2311M21.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":401
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2598
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SPANXN5. Does this perturbation cause a significant change in SPANXN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SPANXN5. Does this perturbation cause a significant change in SPANXN5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3464
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor BCL2L11 expression. Decide whether this perturbation leads to a significant alteration in BCL2L11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor BCL2L11 expression. Decide whether this perturbation leads to a significant alteration in BCL2L11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4928
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of RP11-968A15.2. Does perturbing ETS2 lead to a significant change in RP11-968A15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of RP11-968A15.2. Does perturbing ETS2 lead to a significant change in RP11-968A15.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":831
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor FMNL1 expression. Decide whether this perturbation leads to a significant alteration in FMNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor FMNL1 expression. Decide whether this perturbation leads to a significant alteration in FMNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1698
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3626
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is measured. Determine whether RP11-1085N6.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is measured. Determine whether RP11-1085N6.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3409
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is quantified. Does this perturbation result in a significant change in RP5-1142A6.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is quantified. Does this perturbation result in a significant change in RP5-1142A6.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4712
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5516
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Determine whether RP11-497G19.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-497G19.7 is measured. Determine whether RP11-497G19.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1256
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CCNL1 expression is quantified. Does this perturbation result in a significant change in CCNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and CCNL1 expression is quantified. Does this perturbation result in a significant change in CCNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6142
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and TYROBP expression is quantified. Does this perturbation result in a significant change in TYROBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":562
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":972
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in TMEM88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in TMEM88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5185
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of GRAP2. Does this perturbation cause a significant change in GRAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of GRAP2. Does this perturbation cause a significant change in GRAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":314
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of RP3-525N10.2. Does this perturbation cause a significant change in RP3-525N10.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of RP3-525N10.2. Does this perturbation cause a significant change in RP3-525N10.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5894
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in AVP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3005
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of AC006262.5. Does perturbing ZC3HAV1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of AC006262.5. Does perturbing ZC3HAV1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4981
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":242
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4029
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":85
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1380
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Determine whether C1orf228 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Determine whether C1orf228 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1116
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and DSC1 expression is quantified. Does this perturbation result in a significant change in DSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and DSC1 expression is quantified. Does this perturbation result in a significant change in DSC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1292
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5634
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3307
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in KCNQ1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in KCNQ1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5115
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is quantified. Does this perturbation result in a significant change in RP11-6D1.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is quantified. Does this perturbation result in a significant change in RP11-6D1.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4012
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and STAC3 expression is observed. Does this perturbation lead to a significant difference in STAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and STAC3 expression is observed. Does this perturbation lead to a significant difference in STAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":273
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of RP11-362K14.7. Does this perturbation cause a significant change in RP11-362K14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of RP11-362K14.7. Does this perturbation cause a significant change in RP11-362K14.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4184
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor RP11-202A13.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-202A13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor RP11-202A13.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-202A13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4788
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of BST2. Does perturbing PTPN13 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of BST2. Does perturbing PTPN13 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5631
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and FADS1 expression is measured. Determine whether FADS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1459
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FCER1G expression is measured. Determine whether FCER1G exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5649
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3788
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LRRTM4. Does this perturbation cause a significant change in LRRTM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LRRTM4. Does this perturbation cause a significant change in LRRTM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5844
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ADGRF1. Does this perturbation cause a significant change in ADGRF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of ADGRF1. Does this perturbation cause a significant change in ADGRF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5724
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SLC2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SLC2A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2535
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of RP11-635N19.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of RP11-635N19.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1377
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and GPR35 expression is measured. Determine whether GPR35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and GPR35 expression is measured. Determine whether GPR35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3929
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1168
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of BCL2L11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of BCL2L11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4927
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CTD-2527I21.14 expression. Decide whether this perturbation leads to a significant alteration in CTD-2527I21.14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor CTD-2527I21.14 expression. Decide whether this perturbation leads to a significant alteration in CTD-2527I21.14 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4418
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":917
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of PROX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of PROX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4057
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and FADS1 expression is quantified. Does this perturbation result in a significant change in FADS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1452
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Determine whether RP11-320G24.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RP11-320G24.1 is measured. Determine whether RP11-320G24.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5066
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":259
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Does this perturbation cause a significant change in TRGVA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Does this perturbation cause a significant change in TRGVA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":950
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of RHOXF2BB. Does this perturbation cause a significant change in RHOXF2BB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of RHOXF2BB. Does this perturbation cause a significant change in RHOXF2BB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5714
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":805
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Does this perturbation cause a significant change in TTC9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Does this perturbation cause a significant change in TTC9B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4490
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4570
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is measured. Determine whether RP11-635N19.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is measured. Determine whether RP11-635N19.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1379
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and LEFTY1 expression is measured. Determine whether LEFTY1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and LEFTY1 expression is measured. Determine whether LEFTY1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5919
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5028
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4157
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5764
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and LGALS12 expression is measured. Determine whether LGALS12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and LGALS12 expression is measured. Determine whether LGALS12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":189
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and CRABP2 expression is measured. Determine whether CRABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and CRABP2 expression is measured. Determine whether CRABP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":289
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of MAOB. Does perturbing SLC6A9 lead to a significant change in MAOB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of MAOB. Does perturbing SLC6A9 lead to a significant change in MAOB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1491
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and IFIT2 expression is measured. Determine whether IFIT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and IFIT2 expression is measured. Determine whether IFIT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6029
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HHEX expression is measured. Determine whether HHEX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and HHEX expression is measured. Determine whether HHEX exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3389
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of CTD-2378E12.1 is measured. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6270
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and NUMB expression is quantified. Does this perturbation result in a significant change in NUMB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and NUMB expression is quantified. Does this perturbation result in a significant change in NUMB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3262
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Does this perturbation cause a significant change in COTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Does this perturbation cause a significant change in COTL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1280
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4105
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":803
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and C1orf162 expression is measured. Determine whether C1orf162 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and C1orf162 expression is measured. Determine whether C1orf162 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3539
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RNF168 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in RNF168 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":775
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CHI3L2 expression is quantified. Does this perturbation result in a significant change in CHI3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5982
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and CALY expression is measured. Determine whether CALY exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and CALY expression is measured. Determine whether CALY exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1599
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and MTURN expression is observed. Does this perturbation lead to a significant difference in MTURN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1883
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor APOBR expression. Decide whether this perturbation leads to a significant alteration in APOBR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor APOBR expression. Decide whether this perturbation leads to a significant alteration in APOBR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5178
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and DST expression is measured. Determine whether DST exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2349
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIST1H2AC is measured. Determine whether HIST1H2AC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3186
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and SLC8A1 expression is quantified. Does this perturbation result in a significant change in SLC8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and SLC8A1 expression is quantified. Does this perturbation result in a significant change in SLC8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4552
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2580
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and TFRC expression is observed. Does this perturbation lead to a significant difference in TFRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and TFRC expression is observed. Does this perturbation lead to a significant difference in TFRC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1223
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CCNL1 expression. Decide whether this perturbation leads to a significant alteration in CCNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor CCNL1 expression. Decide whether this perturbation leads to a significant alteration in CCNL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6148
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor MME expression. Decide whether this perturbation leads to a significant alteration in MME expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor MME expression. Decide whether this perturbation leads to a significant alteration in MME expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6268
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ARHGEF6 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor ARHGEF6 expression. Decide whether this perturbation leads to a significant alteration in ARHGEF6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2118
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LRRTM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LRRTM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5845
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTD-3037G24.4. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTD-3037G24.4. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1434
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4278
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of CEBPD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of CEBPD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6067
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is measured. Determine whether PRKAG2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is measured. Determine whether PRKAG2-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3169
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and PDE1B expression is quantified. Does this perturbation result in a significant change in PDE1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and PDE1B expression is quantified. Does this perturbation result in a significant change in PDE1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":32
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor ID1 expression. Decide whether this perturbation leads to a significant alteration in ID1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4868
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor RELB expression. Decide whether this perturbation leads to a significant alteration in RELB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor RELB expression. Decide whether this perturbation leads to a significant alteration in RELB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5658
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2305
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of C19orf38. Does this perturbation cause a significant change in C19orf38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of C19orf38. Does this perturbation cause a significant change in C19orf38 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4844
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":859
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1920
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and SH3RF2 expression is measured. Determine whether SH3RF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and SH3RF2 expression is measured. Determine whether SH3RF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3239
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and MYO1F expression is measured. Determine whether MYO1F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and MYO1F expression is measured. Determine whether MYO1F exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1519
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CIB3. Does perturbing CEBPB lead to a significant change in CIB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CIB3. Does perturbing CEBPB lead to a significant change in CIB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5221
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of COTL1. Does this perturbation cause a significant change in COTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of COTL1. Does this perturbation cause a significant change in COTL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1284
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3080
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Determine whether SLC31A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of SLC31A2 is measured. Determine whether SLC31A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5416
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SKAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of SKAP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":717
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor TOR3A expression. Decide whether this perturbation leads to a significant alteration in TOR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor TOR3A expression. Decide whether this perturbation leads to a significant alteration in TOR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5348
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of FZD6. Does this perturbation cause a significant change in FZD6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of FZD6. Does this perturbation cause a significant change in FZD6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2994
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1724
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Does this perturbation cause a significant change in LRRTM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LRRTM4 is measured. Does this perturbation cause a significant change in LRRTM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5840
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and BCL2L11 expression is quantified. Does this perturbation result in a significant change in BCL2L11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and BCL2L11 expression is quantified. Does this perturbation result in a significant change in BCL2L11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4922
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Determine whether GRN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5886
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SAT1. Does this perturbation cause a significant change in SAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1804
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4042
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and MSX1 expression is observed. Does this perturbation lead to a significant difference in MSX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and MSX1 expression is observed. Does this perturbation lead to a significant difference in MSX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4033
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ARHGEF6 expression is observed. Does this perturbation lead to a significant difference in ARHGEF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and ARHGEF6 expression is observed. Does this perturbation lead to a significant difference in ARHGEF6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2113
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLEKHO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLEKHO1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6125
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of NKG7. Does perturbing ISL2 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of NKG7. Does perturbing ISL2 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4461
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Determine whether MYC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Determine whether MYC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3026
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of CBL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of CBL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3147
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Does this perturbation cause a significant change in S100A4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Does this perturbation cause a significant change in S100A4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1040
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and SSTR3 expression is observed. Does this perturbation lead to a significant difference in SSTR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and SSTR3 expression is observed. Does this perturbation lead to a significant difference in SSTR3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3173
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Does this perturbation cause a significant change in CD9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3740
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is measured. Determine whether HIPK1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is measured. Determine whether HIPK1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3229
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5390
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLA2G16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of PLA2G16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6157
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of ZC3HAV1. Does this perturbation cause a significant change in ZC3HAV1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3194
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1654
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1484
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Does this perturbation cause a significant change in MT1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Does this perturbation cause a significant change in MT1E expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":360
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5746
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and SLC22A11 expression is observed. Does this perturbation lead to a significant difference in SLC22A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and SLC22A11 expression is observed. Does this perturbation lead to a significant difference in SLC22A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4303
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Determine whether MAP7D1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2726
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CTD-2378E12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2378E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CTD-2378E12.1 expression is observed. Does this perturbation lead to a significant difference in CTD-2378E12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6273
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3015
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and GIPR expression is observed. Does this perturbation lead to a significant difference in GIPR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and GIPR expression is observed. Does this perturbation lead to a significant difference in GIPR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5353
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1742
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Determine whether TFAP2A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Determine whether TFAP2A-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4366
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is measured. Determine whether RP3-525N10.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is measured. Determine whether RP3-525N10.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5899
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":916
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AC007246.3 expression is quantified. Does this perturbation result in a significant change in AC007246.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AC007246.3 expression is quantified. Does this perturbation result in a significant change in AC007246.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2292
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-1017G21.6. Does perturbing ARRDC3 lead to a significant change in RP11-1017G21.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-1017G21.6. Does perturbing ARRDC3 lead to a significant change in RP11-1017G21.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3821
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ACTB expression. Decide whether this perturbation leads to a significant alteration in ACTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ACTB expression. Decide whether this perturbation leads to a significant alteration in ACTB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2088
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ST3GAL5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in ST3GAL5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1765
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Determine whether S100A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1826
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of IER3. Does perturbing FOSB lead to a significant change in IER3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of IER3. Does perturbing FOSB lead to a significant change in IER3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2761
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of CCR10. Does perturbing SLC6A9 lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of CCR10. Does perturbing SLC6A9 lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1481
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1656
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of AC007556.3. Does perturbing ETS2 lead to a significant change in AC007556.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of AC007556.3. Does perturbing ETS2 lead to a significant change in AC007556.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":821
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD47 expression. Decide whether this perturbation leads to a significant alteration in CD47 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD47 expression. Decide whether this perturbation leads to a significant alteration in CD47 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":788
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TMEM55A expression is observed. Does this perturbation lead to a significant difference in TMEM55A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TMEM55A expression is observed. Does this perturbation lead to a significant difference in TMEM55A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4603
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and GPR157 expression is observed. Does this perturbation lead to a significant difference in GPR157 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and GPR157 expression is observed. Does this perturbation lead to a significant difference in GPR157 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3053
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-505P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-505P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2557
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and HOXB6 expression is measured. Determine whether HOXB6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and HOXB6 expression is measured. Determine whether HOXB6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":819
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor CBL expression. Decide whether this perturbation leads to a significant alteration in CBL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor CBL expression. Decide whether this perturbation leads to a significant alteration in CBL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3148
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TRIM31 expression is measured. Determine whether TRIM31 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TRIM31 expression is measured. Determine whether TRIM31 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":469
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ARPC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ARPC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":845
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and VCX3B expression is measured. Determine whether VCX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and VCX3B expression is measured. Determine whether VCX3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":159
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and PXK expression is observed. Does this perturbation lead to a significant difference in PXK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and PXK expression is observed. Does this perturbation lead to a significant difference in PXK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2173
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of KCNQ1-AS1. Does perturbing SPI1 lead to a significant change in KCNQ1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of KCNQ1-AS1. Does perturbing SPI1 lead to a significant change in KCNQ1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5111
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LRRC74B expression is observed. Does this perturbation lead to a significant difference in LRRC74B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LRRC74B expression is observed. Does this perturbation lead to a significant difference in LRRC74B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4653
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ARL6IP1 expression is quantified. Does this perturbation result in a significant change in ARL6IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ARL6IP1 expression is quantified. Does this perturbation result in a significant change in ARL6IP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2932
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CITED2 expression is quantified. Does this perturbation result in a significant change in CITED2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CITED2 expression is quantified. Does this perturbation result in a significant change in CITED2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4282
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RIT1 expression is observed. Does this perturbation lead to a significant difference in RIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RIT1 expression is observed. Does this perturbation lead to a significant difference in RIT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4913
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and RP11-180M15.6 expression is observed. Does this perturbation lead to a significant difference in RP11-180M15.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and RP11-180M15.6 expression is observed. Does this perturbation lead to a significant difference in RP11-180M15.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4433
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CFH. Does perturbing TGFBR2 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CFH. Does perturbing TGFBR2 lead to a significant change in CFH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5441
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2054
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C6orf1. Does this perturbation cause a significant change in C6orf1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C6orf1. Does this perturbation cause a significant change in C6orf1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1874
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PTRF expression. Decide whether this perturbation leads to a significant alteration in PTRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor PTRF expression. Decide whether this perturbation leads to a significant alteration in PTRF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1038
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and FNDC3A expression is quantified. Does this perturbation result in a significant change in FNDC3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and FNDC3A expression is quantified. Does this perturbation result in a significant change in FNDC3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4582
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of FABP3. Does this perturbation cause a significant change in FABP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of FABP3. Does this perturbation cause a significant change in FABP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3724
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2122
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of RP11-362K14.7. Does perturbing KIAA1804 lead to a significant change in RP11-362K14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of RP11-362K14.7. Does perturbing KIAA1804 lead to a significant change in RP11-362K14.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4181
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Does this perturbation cause a significant change in MMP19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Does this perturbation cause a significant change in MMP19 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":940
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5637
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of RP11-195B3.1. Does perturbing CELF2 lead to a significant change in RP11-195B3.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of RP11-195B3.1. Does perturbing CELF2 lead to a significant change in RP11-195B3.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2211
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1488
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1744
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CREB3L2 expression is measured. Determine whether CREB3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and CREB3L2 expression is measured. Determine whether CREB3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5999
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Does this perturbation cause a significant change in RP11-510J16.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Does this perturbation cause a significant change in RP11-510J16.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1060
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RNF168 expression is measured. Determine whether RNF168 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RNF168 expression is measured. Determine whether RNF168 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":779
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-497G19.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-497G19.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1257
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RGPD5. Does perturbing CITED1 lead to a significant change in RGPD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RGPD5. Does perturbing CITED1 lead to a significant change in RGPD5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5961
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Does this perturbation cause a significant change in PRTN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Does this perturbation cause a significant change in PRTN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1100
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5043
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ABCA13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ABCA13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2097
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and DSC1 expression is observed. Does this perturbation lead to a significant difference in DSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and DSC1 expression is observed. Does this perturbation lead to a significant difference in DSC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1293
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in CSRNP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in CSRNP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4645
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor RGS16 expression. Decide whether this perturbation leads to a significant alteration in RGS16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":218
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Determine whether SPARC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Determine whether SPARC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5526
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MS4A2 expression is quantified. Does this perturbation result in a significant change in MS4A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MS4A2 expression is quantified. Does this perturbation result in a significant change in MS4A2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3932
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":433
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2059
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-128B16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-128B16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1795
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZEB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3205
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Does this perturbation cause a significant change in SPANXD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of SPANXD is measured. Does this perturbation cause a significant change in SPANXD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4190
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in SIGLEC15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in SIGLEC15 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1965
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and CST9L expression is observed. Does this perturbation lead to a significant difference in CST9L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and CST9L expression is observed. Does this perturbation lead to a significant difference in CST9L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3333
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor SOX4 expression. Decide whether this perturbation leads to a significant alteration in SOX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor SOX4 expression. Decide whether this perturbation leads to a significant alteration in SOX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2358
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor HBD expression. Decide whether this perturbation leads to a significant alteration in HBD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4818
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of PRKAG2-AS1. Does perturbing HOXC13 lead to a significant change in PRKAG2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of PRKAG2-AS1. Does perturbing HOXC13 lead to a significant change in PRKAG2-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3161
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1957
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1332
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ARMCX3 expression is observed. Does this perturbation lead to a significant difference in ARMCX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ARMCX3 expression is observed. Does this perturbation lead to a significant difference in ARMCX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3973
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and GYPE expression is quantified. Does this perturbation result in a significant change in GYPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3622
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Determine whether CCNJL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Determine whether CCNJL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5126
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6108
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of AVP. Does perturbing MAML2 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of AVP. Does perturbing MAML2 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":61
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2523
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in RSPO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in RSPO4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4115
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Does this perturbation cause a significant change in TUBB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Does this perturbation cause a significant change in TUBB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3590
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of UBE2H. Does perturbing CDKN1A lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of UBE2H. Does perturbing CDKN1A lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2361
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FAM83A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FAM83A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5625
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and LPAR2 expression is measured. Determine whether LPAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and LPAR2 expression is measured. Determine whether LPAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3109
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and FOXL2 expression is quantified. Does this perturbation result in a significant change in FOXL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3682
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTD-3037G24.4. Does perturbing UBASH3B lead to a significant change in CTD-3037G24.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTD-3037G24.4. Does perturbing UBASH3B lead to a significant change in CTD-3037G24.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1431
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Does this perturbation cause a significant change in RP11-563J2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Does this perturbation cause a significant change in RP11-563J2.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3810
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HCN1. Does perturbing IKZF3 lead to a significant change in HCN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of HCN1. Does perturbing IKZF3 lead to a significant change in HCN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3041
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in CD24 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3575
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and CTNNB1 expression is quantified. Does this perturbation result in a significant change in CTNNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":502
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CCS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":137
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Determine whether TMEM88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Determine whether TMEM88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5186
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and RBM5-AS1 expression is measured. Determine whether RBM5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and RBM5-AS1 expression is measured. Determine whether RBM5-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":169
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of TNFAIP8. Does this perturbation cause a significant change in TNFAIP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of TNFAIP8. Does this perturbation cause a significant change in TNFAIP8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2184
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of SP6. Does perturbing HES7 lead to a significant change in SP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of SP6. Does perturbing HES7 lead to a significant change in SP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1701
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-646I6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-646I6.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1075
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and AC074289.1 expression is measured. Determine whether AC074289.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4859
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor IL1RN expression. Decide whether this perturbation leads to a significant alteration in IL1RN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor IL1RN expression. Decide whether this perturbation leads to a significant alteration in IL1RN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2198
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5085
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Determine whether DEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Determine whether DEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1676
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1472
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":420
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ATP8A1 expression is measured. Determine whether ATP8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ATP8A1 expression is measured. Determine whether ATP8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3529
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SDSL expression is observed. Does this perturbation lead to a significant difference in SDSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SDSL expression is observed. Does this perturbation lead to a significant difference in SDSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2423
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is quantified. Does this perturbation result in a significant change in KCNQ1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is quantified. Does this perturbation result in a significant change in KCNQ1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5112
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RP11-285F7.2 expression is measured. Determine whether RP11-285F7.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RP11-285F7.2 expression is measured. Determine whether RP11-285F7.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4909
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1324
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Does this perturbation cause a significant change in PHGDH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4500
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SLC2A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SLC2A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1997
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01420 expression. Decide whether this perturbation leads to a significant alteration in LINC01420 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor LINC01420 expression. Decide whether this perturbation leads to a significant alteration in LINC01420 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5428
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and SLCO6A1 expression is measured. Determine whether SLCO6A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and SLCO6A1 expression is measured. Determine whether SLCO6A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4359
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and CPVL expression is measured. Determine whether CPVL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and CPVL expression is measured. Determine whether CPVL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4939
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3714
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Determine whether CDK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Determine whether CDK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4406
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2362
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Determine whether C17orf64 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1716
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4215
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4862
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and GRAP2 expression is quantified. Does this perturbation result in a significant change in GRAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and GRAP2 expression is quantified. Does this perturbation result in a significant change in GRAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":312
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor N4BP2L2 expression. Decide whether this perturbation leads to a significant alteration in N4BP2L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor N4BP2L2 expression. Decide whether this perturbation leads to a significant alteration in N4BP2L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4228
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HCN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in HCN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3045
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNDC3B expression is quantified. Does this perturbation result in a significant change in RUNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNDC3B expression is quantified. Does this perturbation result in a significant change in RUNDC3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2802
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor FAM46C expression. Decide whether this perturbation leads to a significant alteration in FAM46C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor FAM46C expression. Decide whether this perturbation leads to a significant alteration in FAM46C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2898
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of RP11-38J22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of RP11-38J22.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6077
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of THBS1. Does this perturbation cause a significant change in THBS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3214
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":870
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTB-161C1.1 expression. Decide whether this perturbation leads to a significant alteration in CTB-161C1.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1418
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in S100A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in S100A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1915
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of KCNQ1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of KCNQ1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5117
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and HBE1 expression is quantified. Does this perturbation result in a significant change in HBE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and HBE1 expression is quantified. Does this perturbation result in a significant change in HBE1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":442
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and CALY expression is observed. Does this perturbation lead to a significant difference in CALY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and CALY expression is observed. Does this perturbation lead to a significant difference in CALY expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1593
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":303
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Does this perturbation cause a significant change in ACTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Does this perturbation cause a significant change in ACTB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2080
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Determine whether AREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Determine whether AREG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2506
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of TEX30. Does this perturbation cause a significant change in TEX30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of TEX30. Does this perturbation cause a significant change in TEX30 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2414
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4168
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CENPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CENPE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6225
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in C1orf141 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in C1orf141 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2335
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is quantified. Does this perturbation result in a significant change in RP11-646I6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and RP11-646I6.6 expression is quantified. Does this perturbation result in a significant change in RP11-646I6.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1072
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Determine whether INADL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Determine whether INADL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2256
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5743
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of RP3-467K16.2. Does perturbing BCL2L11 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of RP3-467K16.2. Does perturbing BCL2L11 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4951
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTSL expression is observed. Does this perturbation lead to a significant difference in CTSL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1093
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4232
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP11-445O3.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445O3.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP11-445O3.3 expression is observed. Does this perturbation lead to a significant difference in RP11-445O3.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":43
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is quantified. Does this perturbation result in a significant change in RP1-261G23.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and RP1-261G23.7 expression is quantified. Does this perturbation result in a significant change in RP1-261G23.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1902
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in HIST1H3H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in HIST1H3H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5335
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ATP10D expression is quantified. Does this perturbation result in a significant change in ATP10D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and ATP10D expression is quantified. Does this perturbation result in a significant change in ATP10D expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2922
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor CCNJL expression. Decide whether this perturbation leads to a significant alteration in CCNJL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor CCNJL expression. Decide whether this perturbation leads to a significant alteration in CCNJL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5128
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-52L5.6 expression is observed. Does this perturbation lead to a significant difference in RP11-52L5.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and RP11-52L5.6 expression is observed. Does this perturbation lead to a significant difference in RP11-52L5.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6203
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in TAPBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in TAPBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2235
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in CTD-2616J11.16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in CTD-2616J11.16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1195
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Determine whether RP11-328J14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Determine whether RP11-328J14.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2576
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CCRL2. Does this perturbation cause a significant change in CCRL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":344
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Determine whether CALY shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Determine whether CALY shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1596
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Does this perturbation cause a significant change in ZMYND15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Does this perturbation cause a significant change in ZMYND15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2730
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and REEP6 expression is quantified. Does this perturbation result in a significant change in REEP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and REEP6 expression is quantified. Does this perturbation result in a significant change in REEP6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2002
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of N4BP2L2. Does this perturbation cause a significant change in N4BP2L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of N4BP2L2. Does this perturbation cause a significant change in N4BP2L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4224
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5705
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor MAOB expression. Decide whether this perturbation leads to a significant alteration in MAOB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor MAOB expression. Decide whether this perturbation leads to a significant alteration in MAOB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1498
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":567
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of RABAC1. Does perturbing STIL lead to a significant change in RABAC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of RABAC1. Does perturbing STIL lead to a significant change in RABAC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5141
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in MSRB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in MSRB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2655
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4370
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and FCGR3A expression is quantified. Does this perturbation result in a significant change in FCGR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and FCGR3A expression is quantified. Does this perturbation result in a significant change in FCGR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5602
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MS4A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in MS4A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3935
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor MTURN expression. Decide whether this perturbation leads to a significant alteration in MTURN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor MTURN expression. Decide whether this perturbation leads to a significant alteration in MTURN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1888
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of RP11-714G18.1. Does perturbing FOXO4 lead to a significant change in RP11-714G18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of RP11-714G18.1. Does perturbing FOXO4 lead to a significant change in RP11-714G18.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1851
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of TNNI3. Does this perturbation cause a significant change in TNNI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2704
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4683
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and SOX4 expression is observed. Does this perturbation lead to a significant difference in SOX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and SOX4 expression is observed. Does this perturbation lead to a significant difference in SOX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2353
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of ACTB is measured. Determine whether ACTB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2086
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Determine whether MFSD2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6096
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Determine whether AIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Determine whether AIM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3126
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":329
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4774
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and GRN expression is measured. Determine whether GRN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5889
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD47 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in CD47 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":785
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of MOGAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of MOGAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5537
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and AC004540.4 expression is measured. Determine whether AC004540.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and AC004540.4 expression is measured. Determine whether AC004540.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4129
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and TFAP2A expression is measured. Determine whether TFAP2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and TFAP2A expression is measured. Determine whether TFAP2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2319
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Determine whether CYP2C18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Determine whether CYP2C18 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":936
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of EMP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of EMP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3037
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in AFMID expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5505
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of EGOT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of EGOT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5677
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ARRDC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of ARRDC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":237
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is quantified. Does this perturbation result in a significant change in RP3-510H16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is quantified. Does this perturbation result in a significant change in RP3-510H16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3832
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor SLC22A13 expression. Decide whether this perturbation leads to a significant alteration in SLC22A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor SLC22A13 expression. Decide whether this perturbation leads to a significant alteration in SLC22A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4008
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and VMP1 expression is measured. Determine whether VMP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and VMP1 expression is measured. Determine whether VMP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5869
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and RP11-369K17.1 expression is observed. Does this perturbation lead to a significant difference in RP11-369K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and RP11-369K17.1 expression is observed. Does this perturbation lead to a significant difference in RP11-369K17.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5473
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of AC074289.1. Does this perturbation cause a significant change in AC074289.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4854
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and LPAR2 expression is quantified. Does this perturbation result in a significant change in LPAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and LPAR2 expression is quantified. Does this perturbation result in a significant change in LPAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3102
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CRAT37 expression. Decide whether this perturbation leads to a significant alteration in CRAT37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CRAT37 expression. Decide whether this perturbation leads to a significant alteration in CRAT37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6198
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of SLC7A11. Does this perturbation cause a significant change in SLC7A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of SLC7A11. Does this perturbation cause a significant change in SLC7A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4894
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIPK1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIPK1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3225
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of SLC31A2. Does perturbing CDKN1B lead to a significant change in SLC31A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of SLC31A2. Does perturbing CDKN1B lead to a significant change in SLC31A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5411
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of GIPC2 is measured. Determine whether GIPC2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3156
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ARPC3 expression. Decide whether this perturbation leads to a significant alteration in ARPC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ARPC3 expression. Decide whether this perturbation leads to a significant alteration in ARPC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":848
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in DYNLT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in DYNLT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2675
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Determine whether CD47 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Determine whether CD47 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":786
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and RELB expression is measured. Determine whether RELB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and RELB expression is measured. Determine whether RELB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5659
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of PHGDH. Does this perturbation cause a significant change in PHGDH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4504
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and HMGA2 expression is observed. Does this perturbation lead to a significant difference in HMGA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and HMGA2 expression is observed. Does this perturbation lead to a significant difference in HMGA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3893
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4855
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of TEX30. Does perturbing PTPN1 lead to a significant change in TEX30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of TEX30. Does perturbing PTPN1 lead to a significant change in TEX30 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2411
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1153
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5275
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and SLC43A2 expression is observed. Does this perturbation lead to a significant difference in SLC43A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and SLC43A2 expression is observed. Does this perturbation lead to a significant difference in SLC43A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1533
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":557
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CKS2 expression is quantified. Does this perturbation result in a significant change in CKS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CKS2 expression is quantified. Does this perturbation result in a significant change in CKS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2072
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LRRC74B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LRRC74B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4657
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3196
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LGALS1. Does perturbing CSRNP1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LGALS1. Does perturbing CSRNP1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4631
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3606
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4219
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in CCNB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4335
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5766
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SLC2A3 expression is observed. Does this perturbation lead to a significant difference in SLC2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SLC2A3 expression is observed. Does this perturbation lead to a significant difference in SLC2A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2533
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is quantified. Does this perturbation result in a significant change in CTD-2616J11.16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is quantified. Does this perturbation result in a significant change in CTD-2616J11.16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1192
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Does this perturbation cause a significant change in SH3RF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of SH3RF2 is measured. Does this perturbation cause a significant change in SH3RF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3230
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Determine whether RP11-308D13.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RP11-308D13.3 is measured. Determine whether RP11-308D13.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":766
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and H1FNT expression is quantified. Does this perturbation result in a significant change in H1FNT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and H1FNT expression is quantified. Does this perturbation result in a significant change in H1FNT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2912
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":55
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and LBH expression is measured. Determine whether LBH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and LBH expression is measured. Determine whether LBH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5939
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CHP1 expression is observed. Does this perturbation lead to a significant difference in CHP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5463
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and PHGDH expression is observed. Does this perturbation lead to a significant difference in PHGDH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4503
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of YPEL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of YPEL3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5757
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of DSC1. Does this perturbation cause a significant change in DSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of DSC1. Does this perturbation cause a significant change in DSC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1294
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CITED2. Does this perturbation cause a significant change in CITED2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CITED2. Does this perturbation cause a significant change in CITED2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4284
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of RP11-505P4.6. Does this perturbation cause a significant change in RP11-505P4.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of RP11-505P4.6. Does this perturbation cause a significant change in RP11-505P4.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1134
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of FAM178B. Does this perturbation cause a significant change in FAM178B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2604
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and EWSAT1 expression is measured. Determine whether EWSAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and EWSAT1 expression is measured. Determine whether EWSAT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5319
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Does this perturbation cause a significant change in RPL17-C18orf32 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5770
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6112
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":722
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of PRTN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of PRTN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1107
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is quantified. Does this perturbation result in a significant change in RP11-445F12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is quantified. Does this perturbation result in a significant change in RP11-445F12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":602
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-219B4.7 expression is measured. Determine whether RP11-219B4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-219B4.7 expression is measured. Determine whether RP11-219B4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1779
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Determine whether RASGRF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Determine whether RASGRF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1546
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in TUBB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in TUBB3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3595
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Determine whether FCGR2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":546
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ANTXR2. Does this perturbation cause a significant change in ANTXR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of ANTXR2. Does this perturbation cause a significant change in ANTXR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5584
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Does this perturbation cause a significant change in BLVRB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2120
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6184
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Determine whether LBH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Determine whether LBH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5936
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and SLC38A2 expression is observed. Does this perturbation lead to a significant difference in SLC38A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and SLC38A2 expression is observed. Does this perturbation lead to a significant difference in SLC38A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5693
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of XK. Does this perturbation cause a significant change in XK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of XK. Does this perturbation cause a significant change in XK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2624
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RHOH expression is observed. Does this perturbation lead to a significant difference in RHOH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and RHOH expression is observed. Does this perturbation lead to a significant difference in RHOH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4453
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and S100A1 expression is measured. Determine whether S100A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and S100A1 expression is measured. Determine whether S100A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1759
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in FCGR2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":545
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and SOCS1 expression is observed. Does this perturbation lead to a significant difference in SOCS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1393
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Determine whether NUMB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Determine whether NUMB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3266
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ATG2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ATG2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3637
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4972
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CYP3A5 expression. Decide whether this perturbation leads to a significant alteration in CYP3A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CYP3A5 expression. Decide whether this perturbation leads to a significant alteration in CYP3A5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":868
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor FLJ12825 expression. Decide whether this perturbation leads to a significant alteration in FLJ12825 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor FLJ12825 expression. Decide whether this perturbation leads to a significant alteration in FLJ12825 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":178
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of VCX3B. Does perturbing CEBPE lead to a significant change in VCX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of VCX3B. Does perturbing CEBPE lead to a significant change in VCX3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":151
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and GPR157 expression is quantified. Does this perturbation result in a significant change in GPR157 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and GPR157 expression is quantified. Does this perturbation result in a significant change in GPR157 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3052
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and TMEM154 expression is observed. Does this perturbation lead to a significant difference in TMEM154 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and TMEM154 expression is observed. Does this perturbation lead to a significant difference in TMEM154 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4143
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5927
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Determine whether TRIM22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4596
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":68
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIST1H2AC. Does perturbing CKS1B lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIST1H2AC. Does perturbing CKS1B lead to a significant change in HIST1H2AC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3181
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4867
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of FAM101B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":307
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor TEX30 expression. Decide whether this perturbation leads to a significant alteration in TEX30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor TEX30 expression. Decide whether this perturbation leads to a significant alteration in TEX30 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2418
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Determine whether XK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Determine whether XK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2626
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CACNA1C-AS2 expression. Decide whether this perturbation leads to a significant alteration in CACNA1C-AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CACNA1C-AS2 expression. Decide whether this perturbation leads to a significant alteration in CACNA1C-AS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":358
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6238
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":302
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CYP2C18 expression is observed. Does this perturbation lead to a significant difference in CYP2C18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CYP2C18 expression is observed. Does this perturbation lead to a significant difference in CYP2C18 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":933
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in PRKAG2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in PRKAG2-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3165
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and AC004540.4 expression is observed. Does this perturbation lead to a significant difference in AC004540.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and AC004540.4 expression is observed. Does this perturbation lead to a significant difference in AC004540.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4123
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLA2G1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLA2G1B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":757
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2489
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in RP11-195C7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in RP11-195C7.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1735
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and COL1A1 expression is quantified. Does this perturbation result in a significant change in COL1A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and COL1A1 expression is quantified. Does this perturbation result in a significant change in COL1A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5052
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1385
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and RIMBP3C expression is measured. Determine whether RIMBP3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and RIMBP3C expression is measured. Determine whether RIMBP3C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3289
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Determine whether MKNK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Determine whether MKNK2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1626
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TUBA1A expression is measured. Determine whether TUBA1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and TUBA1A expression is measured. Determine whether TUBA1A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2719
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP6-159A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP6-159A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP6-159A1.4 expression. Decide whether this perturbation leads to a significant alteration in RP6-159A1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2828
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and XK expression is observed. Does this perturbation lead to a significant difference in XK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and XK expression is observed. Does this perturbation lead to a significant difference in XK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2623
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and CLU expression is observed. Does this perturbation lead to a significant difference in CLU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and CLU expression is observed. Does this perturbation lead to a significant difference in CLU expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":13
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ANTXR2. Does perturbing ZBTB10 lead to a significant change in ANTXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of ANTXR2. Does perturbing ZBTB10 lead to a significant change in ANTXR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5581
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in TNFRSF12A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in TNFRSF12A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3905
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CYP1B1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CYP1B1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4317
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3624
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Determine whether ABCA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Determine whether ABCA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4176
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of AREG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of AREG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2507
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Does this perturbation cause a significant change in TDRD12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Does this perturbation cause a significant change in TDRD12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":90
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":675
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of CEBPD. Does this perturbation cause a significant change in CEBPD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of CEBPD. Does this perturbation cause a significant change in CEBPD expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6064
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and PRKCB expression is observed. Does this perturbation lead to a significant difference in PRKCB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4623
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and SOX5 expression is quantified. Does this perturbation result in a significant change in SOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and SOX5 expression is quantified. Does this perturbation result in a significant change in SOX5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2472
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of MSX1. Does this perturbation cause a significant change in MSX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of MSX1. Does this perturbation cause a significant change in MSX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4034
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5940
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-259K5.1 expression is observed. Does this perturbation lead to a significant difference in RP11-259K5.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-259K5.1 expression is observed. Does this perturbation lead to a significant difference in RP11-259K5.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1243
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and FEV expression is measured. Determine whether FEV exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2469
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3558
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Does this perturbation cause a significant change in RIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Does this perturbation cause a significant change in RIT1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4910
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and RIT1 expression is measured. Determine whether RIT1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4919
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TFAP2A-AS1 expression. Decide whether this perturbation leads to a significant alteration in TFAP2A-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TFAP2A-AS1 expression. Decide whether this perturbation leads to a significant alteration in TFAP2A-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4368
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM83F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM83F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2687
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of STAC3. Does this perturbation cause a significant change in STAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of STAC3. Does this perturbation cause a significant change in STAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":274
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in TLN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1525
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Determine whether MT1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of MT1E is measured. Determine whether MT1E shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":366
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and MME expression is quantified. Does this perturbation result in a significant change in MME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and MME expression is quantified. Does this perturbation result in a significant change in MME expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6262
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and FNDC3A expression is observed. Does this perturbation lead to a significant difference in FNDC3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4583
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of AC144568.2. Does this perturbation cause a significant change in AC144568.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of AC144568.2. Does this perturbation cause a significant change in AC144568.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":594
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Determine whether MOGAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of MOGAT2 is measured. Determine whether MOGAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5536
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Determine whether LINC01003 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Determine whether LINC01003 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":456
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in MKNK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in MKNK2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1625
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Determine whether ZMAT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Determine whether ZMAT3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5136
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PAMR1. Does this perturbation cause a significant change in PAMR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of PAMR1. Does this perturbation cause a significant change in PAMR1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4794
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of CCR10. Does this perturbation cause a significant change in CCR10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1864
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2482
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6057
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ATG2A expression is quantified. Does this perturbation result in a significant change in ATG2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ATG2A expression is quantified. Does this perturbation result in a significant change in ATG2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3632
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Determine whether GIPR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of GIPR is measured. Determine whether GIPR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5356
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and CSF3R expression is quantified. Does this perturbation result in a significant change in CSF3R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5572
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Determine whether CCDC159 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Determine whether CCDC159 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4256
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of UCKL1-AS1. Does this perturbation cause a significant change in UCKL1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of UCKL1-AS1. Does this perturbation cause a significant change in UCKL1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5254
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of RP1-261G23.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of RP1-261G23.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1907
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and THBS1 expression is measured. Determine whether THBS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3219
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of RELB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of RELB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5657
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":57
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCM2L. Does perturbing CNN1 lead to a significant change in CCM2L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCM2L. Does perturbing CNN1 lead to a significant change in CCM2L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2141
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of CEBPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of CEBPA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1637
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Determine whether CD59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Determine whether CD59 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2376
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4989
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":554
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":969
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in CTSW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in CTSW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5365
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":564
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of BLVRB. Does perturbing CNN1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of BLVRB. Does perturbing CNN1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2121
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and DCAF13 expression is quantified. Does this perturbation result in a significant change in DCAF13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and DCAF13 expression is quantified. Does this perturbation result in a significant change in DCAF13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3542
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":372
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and MYC expression is quantified. Does this perturbation result in a significant change in MYC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and MYC expression is quantified. Does this perturbation result in a significant change in MYC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3022
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and S100A4 expression is quantified. Does this perturbation result in a significant change in S100A4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and S100A4 expression is quantified. Does this perturbation result in a significant change in S100A4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1042
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and MSX1 expression is measured. Determine whether MSX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and MSX1 expression is measured. Determine whether MSX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4039
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CITED2 expression. Decide whether this perturbation leads to a significant alteration in CITED2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor CITED2 expression. Decide whether this perturbation leads to a significant alteration in CITED2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4288
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor LHX1 expression. Decide whether this perturbation leads to a significant alteration in LHX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":618
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ANTXR2 expression. Decide whether this perturbation leads to a significant alteration in ANTXR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor ANTXR2 expression. Decide whether this perturbation leads to a significant alteration in ANTXR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5588
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor DYNLT3 expression. Decide whether this perturbation leads to a significant alteration in DYNLT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor DYNLT3 expression. Decide whether this perturbation leads to a significant alteration in DYNLT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2678
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Does this perturbation cause a significant change in CRABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Does this perturbation cause a significant change in CRABP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":280
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5407
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4044
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Determine whether TCAF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of TCAF2 is measured. Determine whether TCAF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2976
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4578
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in TM4SF1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in TM4SF1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3755
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Determine whether LPAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Determine whether LPAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3106
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1613
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of C10orf11. Does perturbing CBFA2T3 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of C10orf11. Does perturbing CBFA2T3 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1641
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and HIST1H3H expression is observed. Does this perturbation lead to a significant difference in HIST1H3H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and HIST1H3H expression is observed. Does this perturbation lead to a significant difference in HIST1H3H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5333
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Determine whether C8orf22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Determine whether C8orf22 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1896
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor CTC-490E21.10 expression. Decide whether this perturbation leads to a significant alteration in CTC-490E21.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor CTC-490E21.10 expression. Decide whether this perturbation leads to a significant alteration in CTC-490E21.10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":578
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1163
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":22
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1566
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Determine whether CCM2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Determine whether CCM2L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2146
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ICAM4 expression is observed. Does this perturbation lead to a significant difference in ICAM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and ICAM4 expression is observed. Does this perturbation lead to a significant difference in ICAM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4743
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor TPH2 expression. Decide whether this perturbation leads to a significant alteration in TPH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor TPH2 expression. Decide whether this perturbation leads to a significant alteration in TPH2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3418
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor GPR157 expression. Decide whether this perturbation leads to a significant alteration in GPR157 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor GPR157 expression. Decide whether this perturbation leads to a significant alteration in GPR157 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3058
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Does this perturbation cause a significant change in TUBB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Does this perturbation cause a significant change in TUBB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2640
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4442
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AC007246.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AC007246.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2297
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ANTXR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in ANTXR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5585
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of NUCB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of NUCB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3137
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and NCF4 expression is quantified. Does this perturbation result in a significant change in NCF4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":852
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Does this perturbation cause a significant change in SOCS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4080
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":976
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of HIST1H3H. Does perturbing NIT1 lead to a significant change in HIST1H3H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of HIST1H3H. Does perturbing NIT1 lead to a significant change in HIST1H3H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5331
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ACSL1 expression is measured. Determine whether ACSL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and ACSL1 expression is measured. Determine whether ACSL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2779
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of SH3RF2. Does perturbing CKS1B lead to a significant change in SH3RF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of SH3RF2. Does perturbing CKS1B lead to a significant change in SH3RF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3231
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of TAS2R9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of TAS2R9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":897
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and LTC4S expression is observed. Does this perturbation lead to a significant difference in LTC4S expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and LTC4S expression is observed. Does this perturbation lead to a significant difference in LTC4S expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3643
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Does this perturbation cause a significant change in CPVL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Does this perturbation cause a significant change in CPVL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4930
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-259K5.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of RP11-259K5.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1247
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-219B4.7. Does perturbing AHR lead to a significant change in RP11-219B4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-219B4.7. Does perturbing AHR lead to a significant change in RP11-219B4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1771
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of IGDCC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2327
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":378
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4987
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5923
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of SOCS3. Does perturbing MAPK1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of SOCS3. Does perturbing MAPK1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2841
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1617
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in AREG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in AREG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2505
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Does this perturbation cause a significant change in ARMCX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Does this perturbation cause a significant change in ARMCX3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3970
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of GIPC2 is measured. Does this perturbation cause a significant change in GIPC2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4480
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4886
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor RP11-286H15.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-286H15.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor RP11-286H15.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-286H15.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2518
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Does this perturbation cause a significant change in KRT79 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Does this perturbation cause a significant change in KRT79 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3880
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1157
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CIB3. Does this perturbation cause a significant change in CIB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CIB3. Does this perturbation cause a significant change in CIB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5224
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1010
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of LINC01003. Does this perturbation cause a significant change in LINC01003 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of LINC01003. Does this perturbation cause a significant change in LINC01003 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":454
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Determine whether CCDC136 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Determine whether CCDC136 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5036
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2378E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is quantified. Does this perturbation result in a significant change in CTD-2378E12.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6272
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of RASGRF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of RASGRF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1547
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2047
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CTD-3131K8.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-3131K8.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CTD-3131K8.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-3131K8.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2758
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Determine whether FAM225B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Determine whether FAM225B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5236
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ITGA3. Does perturbing FOXL2 lead to a significant change in ITGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of ITGA3. Does perturbing FOXL2 lead to a significant change in ITGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4131
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and RHOXF2BB expression is observed. Does this perturbation lead to a significant difference in RHOXF2BB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and RHOXF2BB expression is observed. Does this perturbation lead to a significant difference in RHOXF2BB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5713
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor AC064834.2 expression. Decide whether this perturbation leads to a significant alteration in AC064834.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor AC064834.2 expression. Decide whether this perturbation leads to a significant alteration in AC064834.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2448
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CHP1. Does perturbing TGFBR2 lead to a significant change in CHP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of CHP1. Does perturbing TGFBR2 lead to a significant change in CHP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5461
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ADGB expression is measured. Determine whether ADGB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and ADGB expression is measured. Determine whether ADGB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5549
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CCNL1 expression is observed. Does this perturbation lead to a significant difference in CCNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and CCNL1 expression is observed. Does this perturbation lead to a significant difference in CCNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6143
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Does this perturbation cause a significant change in NUMB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of NUMB is measured. Does this perturbation cause a significant change in NUMB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3260
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Determine whether ARRDC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of ARRDC3 is measured. Determine whether ARRDC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":236
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and S100A3 expression is measured. Determine whether S100A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and S100A3 expression is measured. Determine whether S100A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1919
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of WDR88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of WDR88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4727
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of PNMT. Does perturbing PLK4 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of PNMT. Does perturbing PLK4 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3661
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in AC004051.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in AC004051.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1845
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1414
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of SAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1807
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ICAM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of ICAM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4747
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2607
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1267
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PCDHGA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PCDHGA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1305
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of BTG2. Does perturbing SLC6A9 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of BTG2. Does perturbing SLC6A9 lead to a significant change in BTG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1461
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ZMYND15 expression. Decide whether this perturbation leads to a significant alteration in ZMYND15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor ZMYND15 expression. Decide whether this perturbation leads to a significant alteration in ZMYND15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2738
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RP11-308D13.3 expression is measured. Determine whether RP11-308D13.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and RP11-308D13.3 expression is measured. Determine whether RP11-308D13.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":769
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Determine whether POC1B-GALNT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of POC1B-GALNT4 is measured. Determine whether POC1B-GALNT4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1976
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6249
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3430
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of RP11-452C8.1. Does perturbing SGK1 lead to a significant change in RP11-452C8.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of RP11-452C8.1. Does perturbing SGK1 lead to a significant change in RP11-452C8.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4071
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2062
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MS4A2. Does perturbing LYL1 lead to a significant change in MS4A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MS4A2. Does perturbing LYL1 lead to a significant change in MS4A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3931
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and MAP7D1 expression is measured. Determine whether MAP7D1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2729
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of MYB. Does perturbing CNN1 lead to a significant change in MYB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of MYB. Does perturbing CNN1 lead to a significant change in MYB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2101
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Does this perturbation cause a significant change in ARHGDIB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1330
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1812
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of MFSD2A. Does perturbing C3orf72 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of MFSD2A. Does perturbing C3orf72 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3871
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor FILIP1L expression. Decide whether this perturbation leads to a significant alteration in FILIP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2268
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of MT1E. Does this perturbation cause a significant change in MT1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of MT1E. Does this perturbation cause a significant change in MT1E expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":364
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":375
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Does this perturbation cause a significant change in ZNF677 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Does this perturbation cause a significant change in ZNF677 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3090
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Does this perturbation cause a significant change in NPW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Does this perturbation cause a significant change in NPW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6040
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2594
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1132
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Determine whether FZD6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Determine whether FZD6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2996
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C8orf22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in C8orf22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1895
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and LINC01342 expression is observed. Does this perturbation lead to a significant difference in LINC01342 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and LINC01342 expression is observed. Does this perturbation lead to a significant difference in LINC01342 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2203
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ZNF677 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of ZNF677 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3097
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2590
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4985
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1454
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of RP11-76E17.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of RP11-76E17.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3347
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4956
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Determine whether RP11-646I6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Determine whether RP11-646I6.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1076
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is quantified. Does this perturbation result in a significant change in UCKL1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is quantified. Does this perturbation result in a significant change in UCKL1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5252
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4235
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4803
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and AC139099.6 expression is measured. Determine whether AC139099.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and AC139099.6 expression is measured. Determine whether AC139099.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3479
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor FADS1 expression. Decide whether this perturbation leads to a significant alteration in FADS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4108
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CD37. Does perturbing CLDN6 lead to a significant change in CD37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CD37. Does perturbing CLDN6 lead to a significant change in CD37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3241
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in HMOX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5975
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PAMR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PAMR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4797
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of TRGVA. Does this perturbation cause a significant change in TRGVA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of TRGVA. Does this perturbation cause a significant change in TRGVA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":954
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SPANXN5 expression is quantified. Does this perturbation result in a significant change in SPANXN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SPANXN5 expression is quantified. Does this perturbation result in a significant change in SPANXN5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3462
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of DPYSL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of DPYSL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5807
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4808
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and CLU expression is quantified. Does this perturbation result in a significant change in CLU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and CLU expression is quantified. Does this perturbation result in a significant change in CLU expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":12
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor GPR35 expression. Decide whether this perturbation leads to a significant alteration in GPR35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor GPR35 expression. Decide whether this perturbation leads to a significant alteration in GPR35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3928
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":498
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":59
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SLC22A25 expression is measured. Determine whether SLC22A25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and SLC22A25 expression is measured. Determine whether SLC22A25 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1839
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and IGDCC3 expression is quantified. Does this perturbation result in a significant change in IGDCC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2322
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and STRA6 expression is quantified. Does this perturbation result in a significant change in STRA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and STRA6 expression is quantified. Does this perturbation result in a significant change in STRA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":652
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1155
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6093
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of RP11-202A13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of RP11-202A13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4787
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and RPS6KA2 expression is observed. Does this perturbation lead to a significant difference in RPS6KA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and RPS6KA2 expression is observed. Does this perturbation lead to a significant difference in RPS6KA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1603
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4963
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Determine whether CTA-384D8.34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Determine whether CTA-384D8.34 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":646
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA2 expression is quantified. Does this perturbation result in a significant change in ANXA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA2 expression is quantified. Does this perturbation result in a significant change in ANXA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2832
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of MYO1F. Does perturbing MIDN lead to a significant change in MYO1F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of MYO1F. Does perturbing MIDN lead to a significant change in MYO1F expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1511
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of GPR35. Does this perturbation cause a significant change in GPR35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of GPR35. Does this perturbation cause a significant change in GPR35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3924
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and AC007556.3 expression is measured. Determine whether AC007556.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and AC007556.3 expression is measured. Determine whether AC007556.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":829
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of RP11-180M15.6. Does this perturbation cause a significant change in RP11-180M15.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of RP11-180M15.6. Does this perturbation cause a significant change in RP11-180M15.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4434
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ORAI3 expression. Decide whether this perturbation leads to a significant alteration in ORAI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor ORAI3 expression. Decide whether this perturbation leads to a significant alteration in ORAI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1948
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ABCA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of ABCA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4177
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2222
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CRAT37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of CRAT37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6197
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Does this perturbation cause a significant change in PTRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PTRF is measured. Does this perturbation cause a significant change in PTRF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1030
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and TAC3 expression is observed. Does this perturbation lead to a significant difference in TAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and TAC3 expression is observed. Does this perturbation lead to a significant difference in TAC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3803
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and GYPE expression is observed. Does this perturbation lead to a significant difference in GYPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3623
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of RSPO4. Does this perturbation cause a significant change in RSPO4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of RSPO4. Does this perturbation cause a significant change in RSPO4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4114
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of TYROBP. Does perturbing SPI1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of TYROBP. Does perturbing SPI1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5081
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-290K4.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-290K4.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3705
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5080
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in TFRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in TFRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1225
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor PLEK expression. Decide whether this perturbation leads to a significant alteration in PLEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor PLEK expression. Decide whether this perturbation leads to a significant alteration in PLEK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5098
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of PYROXD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5157
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in AMPH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in AMPH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6015
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3376
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of TMEM35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of TMEM35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5017
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of DSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of DSC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1297
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and FEZ1 expression is measured. Determine whether FEZ1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4779
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor UNC5B expression. Decide whether this perturbation leads to a significant alteration in UNC5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor UNC5B expression. Decide whether this perturbation leads to a significant alteration in UNC5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3258
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1265
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Does this perturbation cause a significant change in LMNA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Does this perturbation cause a significant change in LMNA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1680
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Determine whether NPW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of NPW is measured. Determine whether NPW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6046
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and RAB5B expression is measured. Determine whether RAB5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and RAB5B expression is measured. Determine whether RAB5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":689
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor MYC expression. Decide whether this perturbation leads to a significant alteration in MYC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor MYC expression. Decide whether this perturbation leads to a significant alteration in MYC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3028
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and FOXF1 expression is observed. Does this perturbation lead to a significant difference in FOXF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3493
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and TAS2R9 expression is measured. Determine whether TAS2R9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and TAS2R9 expression is measured. Determine whether TAS2R9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":899
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Does this perturbation cause a significant change in GPR35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Does this perturbation cause a significant change in GPR35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3920
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZEB2 expression is observed. Does this perturbation lead to a significant difference in ZEB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3203
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4773
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and INADL expression is quantified. Does this perturbation result in a significant change in INADL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and INADL expression is quantified. Does this perturbation result in a significant change in INADL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2252
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":124
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Determine whether TPH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Determine whether TPH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3416
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CDK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CDK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4407
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1146
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ACSL1 expression. Decide whether this perturbation leads to a significant alteration in ACSL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor ACSL1 expression. Decide whether this perturbation leads to a significant alteration in ACSL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2778
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1450
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CST3. Does this perturbation cause a significant change in CST3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2744
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CPXM1. Does this perturbation cause a significant change in CPXM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CPXM1. Does this perturbation cause a significant change in CPXM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":384
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is quantified. Does this perturbation result in a significant change in RP11-109E24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is quantified. Does this perturbation result in a significant change in RP11-109E24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6212
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of GYPE is measured. Does this perturbation cause a significant change in GYPE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3620
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-109E24.2. Does perturbing EGR1 lead to a significant change in RP11-109E24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-109E24.2. Does perturbing EGR1 lead to a significant change in RP11-109E24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6211
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of BST2. Does perturbing TGFBR2 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of BST2. Does perturbing TGFBR2 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5451
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and PPP4R4 expression is quantified. Does this perturbation result in a significant change in PPP4R4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and PPP4R4 expression is quantified. Does this perturbation result in a significant change in PPP4R4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4612
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is measured. Determine whether RP11-714G18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is measured. Determine whether RP11-714G18.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1859
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1457
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SLC2A1-AS1 expression is observed. Does this perturbation lead to a significant difference in SLC2A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SLC2A1-AS1 expression is observed. Does this perturbation lead to a significant difference in SLC2A1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1993
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in SLC31A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in SLC31A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5415
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Does this perturbation cause a significant change in COL21A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Does this perturbation cause a significant change in COL21A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4420
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SLC2A3 expression. Decide whether this perturbation leads to a significant alteration in SLC2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SLC2A3 expression. Decide whether this perturbation leads to a significant alteration in SLC2A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2538
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is measured. Determine whether RP11-195B3.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is measured. Determine whether RP11-195B3.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2219
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Does this perturbation cause a significant change in YPEL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Does this perturbation cause a significant change in YPEL3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5750
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP11-445O3.3. Does perturbing TSC22D1 lead to a significant change in RP11-445O3.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP11-445O3.3. Does perturbing TSC22D1 lead to a significant change in RP11-445O3.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":41
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":496
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and ZMAT3 expression is measured. Determine whether ZMAT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5139
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Determine whether ZEB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3206
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3437
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Determine whether SLC8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Determine whether SLC8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4556
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of GIPR. Does this perturbation cause a significant change in GIPR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of GIPR. Does this perturbation cause a significant change in GIPR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5354
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and IL20 expression is observed. Does this perturbation lead to a significant difference in IL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and IL20 expression is observed. Does this perturbation lead to a significant difference in IL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3763
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":979
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Does this perturbation cause a significant change in ATP9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Does this perturbation cause a significant change in ATP9A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":530
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ARHGEF6 expression is quantified. Does this perturbation result in a significant change in ARHGEF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and ARHGEF6 expression is quantified. Does this perturbation result in a significant change in ARHGEF6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2112
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4325
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and CCNG2 expression is quantified. Does this perturbation result in a significant change in CCNG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and CCNG2 expression is quantified. Does this perturbation result in a significant change in CCNG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4062
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and REEP6 expression is observed. Does this perturbation lead to a significant difference in REEP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and REEP6 expression is observed. Does this perturbation lead to a significant difference in REEP6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2003
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and DNAJB1 expression is observed. Does this perturbation lead to a significant difference in DNAJB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and DNAJB1 expression is observed. Does this perturbation lead to a significant difference in DNAJB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3863
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of FCGR2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":547
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4462
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and MMP19 expression is quantified. Does this perturbation result in a significant change in MMP19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and MMP19 expression is quantified. Does this perturbation result in a significant change in MMP19 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":942
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and EMP3 expression is quantified. Does this perturbation result in a significant change in EMP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and EMP3 expression is quantified. Does this perturbation result in a significant change in EMP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3032
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1260
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-328J14.1. Does perturbing IER5L lead to a significant change in RP11-328J14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-328J14.1. Does perturbing IER5L lead to a significant change in RP11-328J14.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2571
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Does this perturbation cause a significant change in UBE2H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2360
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1645
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and COTL1 expression is measured. Determine whether COTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and COTL1 expression is measured. Determine whether COTL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1289
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4821
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is measured. Determine whether CTD-2311M21.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is measured. Determine whether CTD-2311M21.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":409
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in POC1B-GALNT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in POC1B-GALNT4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1975
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIPK1-AS1. Does this perturbation cause a significant change in HIPK1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIPK1-AS1. Does this perturbation cause a significant change in HIPK1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3224
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of SOCS3. Does this perturbation cause a significant change in SOCS3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3454
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RCSD1 expression is measured. Determine whether RCSD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1449
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of AIM1. Does perturbing HOXC13 lead to a significant change in AIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of AIM1. Does perturbing HOXC13 lead to a significant change in AIM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3121
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CTD-2031P19.5 expression is measured. Determine whether CTD-2031P19.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CTD-2031P19.5 expression is measured. Determine whether CTD-2031P19.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":889
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Determine whether RP11-452C8.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Determine whether RP11-452C8.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4076
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and CEBPD expression is observed. Does this perturbation lead to a significant difference in CEBPD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and CEBPD expression is observed. Does this perturbation lead to a significant difference in CEBPD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6063
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor TMEM88 expression. Decide whether this perturbation leads to a significant alteration in TMEM88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor TMEM88 expression. Decide whether this perturbation leads to a significant alteration in TMEM88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5188
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in LPAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in LPAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3105
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Determine whether CRABP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of CRABP2 is measured. Determine whether CRABP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":286
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of DYNLT3. Does perturbing TP73 lead to a significant change in DYNLT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of DYNLT3. Does perturbing TP73 lead to a significant change in DYNLT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2671
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5632
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CD59 expression is quantified. Does this perturbation result in a significant change in CD59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and CD59 expression is quantified. Does this perturbation result in a significant change in CD59 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2372
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RUNX3 expression. Decide whether this perturbation leads to a significant alteration in RUNX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RUNX3 expression. Decide whether this perturbation leads to a significant alteration in RUNX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5958
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SLC22A25. Does perturbing FOXO4 lead to a significant change in SLC22A25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SLC22A25. Does perturbing FOXO4 lead to a significant change in SLC22A25 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1831
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TUBB2B. Does perturbing MEIS1 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TUBB2B. Does perturbing MEIS1 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":431
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":746
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1475
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Determine whether FCGR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Determine whether FCGR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5606
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and IGFL2 expression is quantified. Does this perturbation result in a significant change in IGFL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and IGFL2 expression is quantified. Does this perturbation result in a significant change in IGFL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5492
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Determine whether IL1RN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Determine whether IL1RN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2196
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and AREG expression is quantified. Does this perturbation result in a significant change in AREG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and AREG expression is quantified. Does this perturbation result in a significant change in AREG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2502
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and UNC5B expression is measured. Determine whether UNC5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and UNC5B expression is measured. Determine whether UNC5B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3259
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and CCRL2 expression is observed. Does this perturbation lead to a significant difference in CCRL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":343
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5639
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of AREG. Does perturbing TBX2 lead to a significant change in AREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of AREG. Does perturbing TBX2 lead to a significant change in AREG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2501
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and IER3 expression is measured. Determine whether IER3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and IER3 expression is measured. Determine whether IER3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2769
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in INHBE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in INHBE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5785
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of PRTN3. Does perturbing RREB1 lead to a significant change in PRTN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of PRTN3. Does perturbing RREB1 lead to a significant change in PRTN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1101
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor RP11-537H15.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-537H15.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor RP11-537H15.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-537H15.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2278
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and S100A13 expression is measured. Determine whether S100A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1829
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and AIM1 expression is observed. Does this perturbation lead to a significant difference in AIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and AIM1 expression is observed. Does this perturbation lead to a significant difference in AIM1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3123
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of N4BP2L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of N4BP2L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4227
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of TPH2. Does perturbing SAMD1 lead to a significant change in TPH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of TPH2. Does perturbing SAMD1 lead to a significant change in TPH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3411
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor LINC01342 expression. Decide whether this perturbation leads to a significant alteration in LINC01342 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor LINC01342 expression. Decide whether this perturbation leads to a significant alteration in LINC01342 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2208
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and HIST1H4H expression is observed. Does this perturbation lead to a significant difference in HIST1H4H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and HIST1H4H expression is observed. Does this perturbation lead to a significant difference in HIST1H4H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4343
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of CTA-384D8.34. Does perturbing BAK1 lead to a significant change in CTA-384D8.34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of CTA-384D8.34. Does perturbing BAK1 lead to a significant change in CTA-384D8.34 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":641
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNDC3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of RUNDC3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2807
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5980
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and LTC4S expression is measured. Determine whether LTC4S exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and LTC4S expression is measured. Determine whether LTC4S exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3649
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor SP6 expression. Decide whether this perturbation leads to a significant alteration in SP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor SP6 expression. Decide whether this perturbation leads to a significant alteration in SP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1708
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and LINC01003 expression is observed. Does this perturbation lead to a significant difference in LINC01003 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and LINC01003 expression is observed. Does this perturbation lead to a significant difference in LINC01003 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":453
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCM2L expression. Decide whether this perturbation leads to a significant alteration in CCM2L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCM2L expression. Decide whether this perturbation leads to a significant alteration in CCM2L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2148
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ZNF431. Does perturbing CSRNP1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of ZNF431. Does perturbing CSRNP1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4671
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01358. Does perturbing ZBTB10 lead to a significant change in LINC01358 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of LINC01358. Does perturbing ZBTB10 lead to a significant change in LINC01358 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5611
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Determine whether MS4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MS4A3 is measured. Determine whether MS4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":986
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4809
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of SLC43A2. Does perturbing MIDN lead to a significant change in SLC43A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of SLC43A2. Does perturbing MIDN lead to a significant change in SLC43A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1531
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CACNA1C-AS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CACNA1C-AS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":357
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Does this perturbation cause a significant change in RHOH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Does this perturbation cause a significant change in RHOH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4450
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD47. Does this perturbation cause a significant change in CD47 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD47. Does this perturbation cause a significant change in CD47 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":784
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4827
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and REEP6 expression is measured. Determine whether REEP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and REEP6 expression is measured. Determine whether REEP6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2009
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01420 expression is observed. Does this perturbation lead to a significant difference in LINC01420 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01420 expression is observed. Does this perturbation lead to a significant difference in LINC01420 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5423
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of TAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of TAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3807
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is measured. Determine whether RP4-550H1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is measured. Determine whether RP4-550H1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5799
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3610
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in CRABP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in CRABP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":285
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":304
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C8orf22. Does perturbing RHOXF2BB lead to a significant change in C8orf22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C8orf22. Does perturbing RHOXF2BB lead to a significant change in C8orf22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1891
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ARPC3. Does this perturbation cause a significant change in ARPC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ARPC3. Does this perturbation cause a significant change in ARPC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":844
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of TNNI3. Does perturbing HES7 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of TNNI3. Does perturbing HES7 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1721
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of RP11-91A18.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of RP11-91A18.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2697
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1647
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5684
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is measured. Determine whether RP11-505P4.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and RP11-505P4.6 expression is measured. Determine whether RP11-505P4.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1139
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Does this perturbation cause a significant change in MYOZ3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Does this perturbation cause a significant change in MYOZ3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3940
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLAUR. Does perturbing CBL lead to a significant change in PLAUR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLAUR. Does perturbing CBL lead to a significant change in PLAUR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in VASH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in VASH1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3355
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of TRPM2. Does this perturbation cause a significant change in TRPM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of TRPM2. Does this perturbation cause a significant change in TRPM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1424
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and DRC1 expression is observed. Does this perturbation lead to a significant difference in DRC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and DRC1 expression is observed. Does this perturbation lead to a significant difference in DRC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5663
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of GYPE. Does this perturbation cause a significant change in GYPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4754
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3574
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and MMP19 expression is measured. Determine whether MMP19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and MMP19 expression is measured. Determine whether MMP19 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":949
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-328J14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of RP11-328J14.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2577
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":75
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and TLN1 expression is quantified. Does this perturbation result in a significant change in TLN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1522
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of CSF3R is measured. Does this perturbation cause a significant change in CSF3R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5570
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of PRSS57. Does perturbing MEIS1 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":421
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of MAP7D1. Does perturbing MAP7D1 lead to a significant change in MAP7D1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2721
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of SLC8A1. Does this perturbation cause a significant change in SLC8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of SLC8A1. Does this perturbation cause a significant change in SLC8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4554
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Does this perturbation cause a significant change in KIAA2012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Does this perturbation cause a significant change in KIAA2012 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Determine whether RELB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Determine whether RELB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5656
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-510J16.5 expression is observed. Does this perturbation lead to a significant difference in RP11-510J16.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-510J16.5 expression is observed. Does this perturbation lead to a significant difference in RP11-510J16.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1063
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1160
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ANXA2R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in ANXA2R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5875
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Does this perturbation cause a significant change in AC007246.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Does this perturbation cause a significant change in AC007246.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2290
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4159
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in KIF2C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4565
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Does this perturbation cause a significant change in LINC01562 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of LINC01562 is measured. Does this perturbation cause a significant change in LINC01562 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1310
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in CST9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in CST9L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3335
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and SPARC expression is quantified. Does this perturbation result in a significant change in SPARC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and SPARC expression is quantified. Does this perturbation result in a significant change in SPARC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5522
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4150
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ADGB. Does perturbing JUN lead to a significant change in ADGB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of ADGB. Does perturbing JUN lead to a significant change in ADGB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5541
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Does this perturbation cause a significant change in CARMN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Does this perturbation cause a significant change in CARMN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3270
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Determine whether TM4SF1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Determine whether TM4SF1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3756
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TRIM31 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TRIM31 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":465
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of BLVRB. Does this perturbation cause a significant change in BLVRB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6174
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Determine whether PROX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of PROX1 is measured. Determine whether PROX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4056
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-514P8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of RP11-514P8.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3697
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and HCAR2 expression is quantified. Does this perturbation result in a significant change in HCAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and HCAR2 expression is quantified. Does this perturbation result in a significant change in HCAR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5192
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4375
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and CHST15 expression is quantified. Does this perturbation result in a significant change in CHST15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and CHST15 expression is quantified. Does this perturbation result in a significant change in CHST15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2492
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Does this perturbation cause a significant change in LEFTY2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Does this perturbation cause a significant change in LEFTY2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4940
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of SEMA3B. Does perturbing CEBPA lead to a significant change in SEMA3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of SEMA3B. Does perturbing CEBPA lead to a significant change in SEMA3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4241
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of FOXL2. Does this perturbation cause a significant change in FOXL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3684
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and COL21A1 expression is observed. Does this perturbation lead to a significant difference in COL21A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and COL21A1 expression is observed. Does this perturbation lead to a significant difference in COL21A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4423
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and RSPO4 expression is quantified. Does this perturbation result in a significant change in RSPO4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and RSPO4 expression is quantified. Does this perturbation result in a significant change in RSPO4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4112
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5947
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":878
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Does this perturbation cause a significant change in PNMT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":370
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Does this perturbation cause a significant change in HMGA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of HMGA2 is measured. Does this perturbation cause a significant change in HMGA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3890
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Does this perturbation cause a significant change in HOGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Does this perturbation cause a significant change in HOGA1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2860
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and SERPINF1 expression is observed. Does this perturbation lead to a significant difference in SERPINF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and SERPINF1 expression is observed. Does this perturbation lead to a significant difference in SERPINF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1083
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4440
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Does this perturbation cause a significant change in CCM2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCM2L is measured. Does this perturbation cause a significant change in CCM2L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2140
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FCER1G is measured. Does this perturbation cause a significant change in FCER1G expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5640
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ARRDC3 expression is quantified. Does this perturbation result in a significant change in ARRDC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and ARRDC3 expression is quantified. Does this perturbation result in a significant change in ARRDC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":232
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of NBR1. Does perturbing NCL lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of NBR1. Does perturbing NCL lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4881
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of AC004051.2. Does this perturbation cause a significant change in AC004051.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of AC004051.2. Does this perturbation cause a significant change in AC004051.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1844
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RP11-83A24.2. Does perturbing GLB1L2 lead to a significant change in RP11-83A24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RP11-83A24.2. Does perturbing GLB1L2 lead to a significant change in RP11-83A24.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":521
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and TDRD12 expression is measured. Determine whether TDRD12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and TDRD12 expression is measured. Determine whether TDRD12 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":99
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1024
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4027
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and BAK1 expression is observed. Does this perturbation lead to a significant difference in BAK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":623
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in SLC43A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in SLC43A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1535
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of APOL6. Does perturbing COL1A1 lead to a significant change in APOL6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of APOL6. Does perturbing COL1A1 lead to a significant change in APOL6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3421
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCM2L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCM2L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2145
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":790
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":558
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4758
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of DYNLL1. Does this perturbation cause a significant change in DYNLL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of DYNLL1. Does this perturbation cause a significant change in DYNLL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2814
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Does this perturbation cause a significant change in XK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of XK is measured. Does this perturbation cause a significant change in XK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2620
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Determine whether RP11-195B3.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Determine whether RP11-195B3.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2216
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LRRTM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LRRTM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5847
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of ESAM. Does this perturbation cause a significant change in ESAM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5274
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is measured. Determine whether POC1B-GALNT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is measured. Determine whether POC1B-GALNT4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1979
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of PGA4. Does perturbing PRDM1 lead to a significant change in PGA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of PGA4. Does perturbing PRDM1 lead to a significant change in PGA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6031
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ACTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ACTB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2085
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Determine whether SP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Determine whether SP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1706
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of HBG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of HBG1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5387
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MS4A3 expression is quantified. Does this perturbation result in a significant change in MS4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MS4A3 expression is quantified. Does this perturbation result in a significant change in MS4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":982
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of COLGALT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4097
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ETS1. Does this perturbation cause a significant change in ETS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of ETS1. Does this perturbation cause a significant change in ETS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":584
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of SLC38A2. Does perturbing SLC38A2 lead to a significant change in SLC38A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of SLC38A2. Does perturbing SLC38A2 lead to a significant change in SLC38A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5691
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CHI3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":907
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1273
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5513
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of TAS1R1. Does this perturbation cause a significant change in TAS1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of TAS1R1. Does this perturbation cause a significant change in TAS1R1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":704
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of CTD-2616J11.16. Does perturbing ZNF318 lead to a significant change in CTD-2616J11.16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of CTD-2616J11.16. Does perturbing ZNF318 lead to a significant change in CTD-2616J11.16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1191
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of THBS1. Does perturbing CKS1B lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of THBS1. Does perturbing CKS1B lead to a significant change in THBS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3211
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is quantified. Does this perturbation result in a significant change in RP3-467K16.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4952
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of RP11-442O1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of RP11-442O1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4667
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":727
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Does this perturbation cause a significant change in RSPO4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Does this perturbation cause a significant change in RSPO4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4110
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CDC45 expression is measured. Determine whether CDC45 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":129
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FAM83A. Does this perturbation cause a significant change in FAM83A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FAM83A. Does this perturbation cause a significant change in FAM83A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5624
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLA2G16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in PLA2G16 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6155
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5645
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1336
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and NUDC expression is measured. Determine whether NUDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and NUDC expression is measured. Determine whether NUDC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2159
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of TFRC. Does this perturbation cause a significant change in TFRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of TFRC. Does this perturbation cause a significant change in TFRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1224
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and CTSW expression is quantified. Does this perturbation result in a significant change in CTSW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and CTSW expression is quantified. Does this perturbation result in a significant change in CTSW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5362
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of NCKAP1L. Does perturbing HOXB9 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of NCKAP1L. Does perturbing HOXB9 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3081
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-52L5.6. Does this perturbation cause a significant change in RP11-52L5.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-52L5.6. Does this perturbation cause a significant change in RP11-52L5.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6204
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTSL. Does this perturbation cause a significant change in CTSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1094
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CDC20 expression is quantified. Does this perturbation result in a significant change in CDC20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5402
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in MCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in MCC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3515
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CDC45. Does perturbing CDKN1C lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CDC45. Does perturbing CDKN1C lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6241
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and IL20 expression is quantified. Does this perturbation result in a significant change in IL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and IL20 expression is quantified. Does this perturbation result in a significant change in IL20 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3762
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of RP11-505P4.6. Does perturbing RREB1 lead to a significant change in RP11-505P4.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of RP11-505P4.6. Does perturbing RREB1 lead to a significant change in RP11-505P4.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1131
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in SSTR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in SSTR3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3175
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and COLGALT2 expression is measured. Determine whether COLGALT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4099
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RIT1 expression is quantified. Does this perturbation result in a significant change in RIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RIT1 expression is quantified. Does this perturbation result in a significant change in RIT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4912
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor TUBB expression. Decide whether this perturbation leads to a significant alteration in TUBB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor TUBB expression. Decide whether this perturbation leads to a significant alteration in TUBB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2648
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of AIF1. Does perturbing ZNF318 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of AIF1. Does perturbing ZNF318 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1161
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in FZD6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in FZD6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2995
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2599
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ARHGDIB. Does perturbing MAP4K5 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of ARHGDIB. Does perturbing MAP4K5 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1331
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and CRYAB expression is observed. Does this perturbation lead to a significant difference in CRYAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and CRYAB expression is observed. Does this perturbation lead to a significant difference in CRYAB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1343
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and ZFP36L2 expression is observed. Does this perturbation lead to a significant difference in ZFP36L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3673
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and WBP2 expression is quantified. Does this perturbation result in a significant change in WBP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5162
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of LINC01338. Does this perturbation cause a significant change in LINC01338 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of LINC01338. Does this perturbation cause a significant change in LINC01338 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5074
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of RP11-244F12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of RP11-244F12.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4537
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD9. Does this perturbation cause a significant change in CD9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3744
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RP11-285F7.2. Does this perturbation cause a significant change in RP11-285F7.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RP11-285F7.2. Does this perturbation cause a significant change in RP11-285F7.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4904
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4957
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4986
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of UBASH3A. Does perturbing RUNX1T1 lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of UBASH3A. Does perturbing RUNX1T1 lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1951
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RNF213. Does perturbing ISL2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RNF213. Does perturbing ISL2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4471
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and TMEM88 expression is observed. Does this perturbation lead to a significant difference in TMEM88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and TMEM88 expression is observed. Does this perturbation lead to a significant difference in TMEM88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5183
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4025
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2855
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4675
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor PTPRS expression. Decide whether this perturbation leads to a significant alteration in PTPRS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor PTPRS expression. Decide whether this perturbation leads to a significant alteration in PTPRS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":668
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4525
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01420. Does perturbing CDKN1B lead to a significant change in LINC01420 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01420. Does perturbing CDKN1B lead to a significant change in LINC01420 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5421
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1276
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":799
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of CFH is measured. Does this perturbation cause a significant change in CFH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5440
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Determine whether SAT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2886
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Determine whether HOGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of HOGA1 is measured. Determine whether HOGA1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2866
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of KCNH2. Does perturbing COL1A1 lead to a significant change in KCNH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of KCNH2. Does perturbing COL1A1 lead to a significant change in KCNH2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3441
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Determine whether TRAPPC3L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Determine whether TRAPPC3L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6256
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3010
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4810
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and AC020571.3 expression is observed. Does this perturbation lead to a significant difference in AC020571.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and AC020571.3 expression is observed. Does this perturbation lead to a significant difference in AC020571.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1213
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor AVP expression. Decide whether this perturbation leads to a significant alteration in AVP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3008
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-514P8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-514P8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-514P8.2 expression is observed. Does this perturbation lead to a significant difference in RP11-514P8.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3693
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and SLC22A11 expression is quantified. Does this perturbation result in a significant change in SLC22A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and SLC22A11 expression is quantified. Does this perturbation result in a significant change in SLC22A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4302
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of SPARC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of SPARC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5527
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Determine whether COTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of COTL1 is measured. Determine whether COTL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1286
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2543
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in RP11-442O1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in RP11-442O1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4665
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ATG2A. Does perturbing PRTG lead to a significant change in ATG2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of ATG2A. Does perturbing PRTG lead to a significant change in ATG2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3631
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CYP1B1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in CYP1B1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4315
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Determine whether SCG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Determine whether SCG5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5856
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Determine whether CEBPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Determine whether CEBPA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1636
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4852
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and IGFL2 expression is measured. Determine whether IGFL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and IGFL2 expression is measured. Determine whether IGFL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5499
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Determine whether CKS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Determine whether CKS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2076
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and CRABP2 expression is observed. Does this perturbation lead to a significant difference in CRABP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and CRABP2 expression is observed. Does this perturbation lead to a significant difference in CRABP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":283
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of RNF182. Does this perturbation cause a significant change in RNF182 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of RNF182. Does this perturbation cause a significant change in RNF182 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3954
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3667
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in PRTN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in PRTN3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1105
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor MARCKS expression. Decide whether this perturbation leads to a significant alteration in MARCKS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor MARCKS expression. Decide whether this perturbation leads to a significant alteration in MARCKS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4998
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA2 expression is measured. Determine whether ANXA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA2 expression is measured. Determine whether ANXA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2839
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Does this perturbation cause a significant change in SLC43A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of SLC43A2 is measured. Does this perturbation cause a significant change in SLC43A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1530
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3458
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Determine whether AC064834.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of AC064834.2 is measured. Determine whether AC064834.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2446
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in TM6SF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4545
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":925
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HHEX. Does this perturbation cause a significant change in HHEX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of HHEX. Does this perturbation cause a significant change in HHEX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3384
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Determine whether CACNA1C-AS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Determine whether CACNA1C-AS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":356
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RUNX1 expression. Decide whether this perturbation leads to a significant alteration in RUNX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4688
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of RP3-525N10.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of RP3-525N10.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5897
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01227 expression is observed. Does this perturbation lead to a significant difference in LINC01227 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and LINC01227 expression is observed. Does this perturbation lead to a significant difference in LINC01227 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5433
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of PCK1. Does perturbing SLC38A2 lead to a significant change in PCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of PCK1. Does perturbing SLC38A2 lead to a significant change in PCK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5731
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor PNMT expression. Decide whether this perturbation leads to a significant alteration in PNMT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3668
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4482
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of HEMGN. Does perturbing ELMSAN1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of HEMGN. Does perturbing ELMSAN1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":251
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Determine whether ORAI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Determine whether ORAI3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1946
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Does this perturbation cause a significant change in PLEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Does this perturbation cause a significant change in PLEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5090
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Does this perturbation cause a significant change in SKAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Does this perturbation cause a significant change in SKAP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":710
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Does this perturbation cause a significant change in RP11-445O3.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Does this perturbation cause a significant change in RP11-445O3.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":40
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2880
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6233
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2944
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1930
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of CST9L. Does perturbing FOXA3 lead to a significant change in CST9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of CST9L. Does perturbing FOXA3 lead to a significant change in CST9L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3331
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of LINC00479. Does perturbing BCORL1 lead to a significant change in LINC00479 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of LINC00479. Does perturbing BCORL1 lead to a significant change in LINC00479 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":411
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4860
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of SAT2 is measured. Does this perturbation cause a significant change in SAT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3070
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CDC45 expression is quantified. Does this perturbation result in a significant change in CDC45 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6242
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Does this perturbation cause a significant change in RIMBP3C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of RIMBP3C is measured. Does this perturbation cause a significant change in RIMBP3C expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3280
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RP11-83A24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RP11-83A24.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":525
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and FABP3 expression is quantified. Does this perturbation result in a significant change in FABP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and FABP3 expression is quantified. Does this perturbation result in a significant change in FABP3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3722
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SPANXN5 expression is observed. Does this perturbation lead to a significant difference in SPANXN5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SPANXN5 expression is observed. Does this perturbation lead to a significant difference in SPANXN5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3463
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1338
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of RP11-180M15.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of RP11-180M15.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4437
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and ARHGDIB expression is quantified. Does this perturbation result in a significant change in ARHGDIB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4022
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of EWSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of EWSAT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5317
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RUNX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in RUNX3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5955
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4778
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in RP1-261G23.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in RP1-261G23.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1905
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LRRC74B expression is quantified. Does this perturbation result in a significant change in LRRC74B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LRRC74B expression is quantified. Does this perturbation result in a significant change in LRRC74B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4652
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MS4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MS4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":985
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of NCF4. Does perturbing CBL lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of NCF4. Does perturbing CBL lead to a significant change in NCF4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":721
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4815
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of DEK. Does this perturbation cause a significant change in DEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of DEK. Does this perturbation cause a significant change in DEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1674
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-328J14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-328J14.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2575
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and KRT7 expression is observed. Does this perturbation lead to a significant difference in KRT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and KRT7 expression is observed. Does this perturbation lead to a significant difference in KRT7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2793
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of GPR157. Does perturbing IKZF3 lead to a significant change in GPR157 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of GPR157. Does perturbing IKZF3 lead to a significant change in GPR157 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3051
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of PRKCB. Does perturbing ARRDC3 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of PRKCB. Does perturbing ARRDC3 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3791
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2306
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Determine whether PLAUR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Determine whether PLAUR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":736
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CYP2C18 expression. Decide whether this perturbation leads to a significant alteration in CYP2C18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CYP2C18 expression. Decide whether this perturbation leads to a significant alteration in CYP2C18 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":938
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CFH expression is quantified. Does this perturbation result in a significant change in CFH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5442
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Does this perturbation cause a significant change in LINC01358 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Does this perturbation cause a significant change in LINC01358 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5610
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Does this perturbation cause a significant change in PCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Does this perturbation cause a significant change in PCK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5730
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2050
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and RASGRF2 expression is measured. Determine whether RASGRF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and RASGRF2 expression is measured. Determine whether RASGRF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1549
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of LGALS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of LGALS12 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":187
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and BCL2L11 expression is observed. Does this perturbation lead to a significant difference in BCL2L11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and BCL2L11 expression is observed. Does this perturbation lead to a significant difference in BCL2L11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4923
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and CTNNB1 expression is measured. Determine whether CTNNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":509
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor FOXF1 expression. Decide whether this perturbation leads to a significant alteration in FOXF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3498
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1396
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CTD-2012K14.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of CTD-2012K14.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5217
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and ARHGDIB expression is measured. Determine whether ARHGDIB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1339
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":555
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TMEM55A expression is quantified. Does this perturbation result in a significant change in TMEM55A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TMEM55A expression is quantified. Does this perturbation result in a significant change in TMEM55A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4602
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-563J2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-563J2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-563J2.3 expression is observed. Does this perturbation lead to a significant difference in RP11-563J2.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3813
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of SOX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of SOX4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2357
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-563J2.3. Does perturbing ARRDC3 lead to a significant change in RP11-563J2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of RP11-563J2.3. Does perturbing ARRDC3 lead to a significant change in RP11-563J2.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3811
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of TMEM35. Does perturbing ZC3HAV1 lead to a significant change in TMEM35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of TMEM35. Does perturbing ZC3HAV1 lead to a significant change in TMEM35 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5011
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Does this perturbation cause a significant change in CNN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of CNN2 is measured. Does this perturbation cause a significant change in CNN2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4700
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and MACF1 expression is quantified. Does this perturbation result in a significant change in MACF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and MACF1 expression is quantified. Does this perturbation result in a significant change in MACF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4732
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TPM4 expression is observed. Does this perturbation lead to a significant difference in TPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TPM4 expression is observed. Does this perturbation lead to a significant difference in TPM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4513
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor ID3 expression. Decide whether this perturbation leads to a significant alteration in ID3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":248
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of HOGA1. Does this perturbation cause a significant change in HOGA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of HOGA1. Does this perturbation cause a significant change in HOGA1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2864
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and TSC22D4 expression is quantified. Does this perturbation result in a significant change in TSC22D4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":192
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and TRGVA expression is measured. Determine whether TRGVA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and TRGVA expression is measured. Determine whether TRGVA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":959
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CREB3L2 expression is quantified. Does this perturbation result in a significant change in CREB3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and CREB3L2 expression is quantified. Does this perturbation result in a significant change in CREB3L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5992
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and TFRC expression is measured. Determine whether TFRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and TFRC expression is measured. Determine whether TFRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1229
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of HOGA1. Does perturbing MAPK1 lead to a significant change in HOGA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of HOGA1. Does perturbing MAPK1 lead to a significant change in HOGA1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2861
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor SH3BGRL expression. Decide whether this perturbation leads to a significant alteration in SH3BGRL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":398
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in RBM5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in RBM5-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":165
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of RP11-76E17.2. Does this perturbation cause a significant change in RP11-76E17.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of RP11-76E17.2. Does this perturbation cause a significant change in RP11-76E17.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3344
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in UNC5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in UNC5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3255
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in NPW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in NPW expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6045
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":79
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of RP11-968A15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of RP11-968A15.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":837
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2593
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and TAPBP expression is measured. Determine whether TAPBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and TAPBP expression is measured. Determine whether TAPBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2239
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Determine whether FBXL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2526
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ASIC4 expression is observed. Does this perturbation lead to a significant difference in ASIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and ASIC4 expression is observed. Does this perturbation lead to a significant difference in ASIC4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2243
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RUNX3 expression is observed. Does this perturbation lead to a significant difference in RUNX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RUNX3 expression is observed. Does this perturbation lead to a significant difference in RUNX3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5953
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of MSX1. Does perturbing SGK1 lead to a significant change in MSX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of MSX1. Does perturbing SGK1 lead to a significant change in MSX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4031
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CYP2C18 expression is measured. Determine whether CYP2C18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CYP2C18 expression is measured. Determine whether CYP2C18 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":939
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4973
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4230
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in DSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in DSC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1295
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Does this perturbation cause a significant change in MYL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Does this perturbation cause a significant change in MYL4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5560
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of PCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of PCK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5737
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-497G19.7. Does this perturbation cause a significant change in RP11-497G19.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-497G19.7. Does this perturbation cause a significant change in RP11-497G19.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1254
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":978
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3915
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of AC145110.1. Does perturbing HOXB9 lead to a significant change in AC145110.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of AC145110.1. Does perturbing HOXB9 lead to a significant change in AC145110.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3111
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and ORAI3 expression is measured. Determine whether ORAI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1949
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Does this perturbation cause a significant change in IFIT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Does this perturbation cause a significant change in IFIT2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6020
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ACSL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of ACSL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2777
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and NUDC expression is observed. Does this perturbation lead to a significant difference in NUDC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and NUDC expression is observed. Does this perturbation lead to a significant difference in NUDC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2153
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1616
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Determine whether CIB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Determine whether CIB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5226
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of RP11-537H15.3. Does perturbing MAP2K3 lead to a significant change in RP11-537H15.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of RP11-537H15.3. Does perturbing MAP2K3 lead to a significant change in RP11-537H15.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2271
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor SLC22A11 expression. Decide whether this perturbation leads to a significant alteration in SLC22A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor SLC22A11 expression. Decide whether this perturbation leads to a significant alteration in SLC22A11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4308
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4484
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CIB3 expression is quantified. Does this perturbation result in a significant change in CIB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and CIB3 expression is quantified. Does this perturbation result in a significant change in CIB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5222
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTD-3037G24.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTD-3037G24.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1435
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ZIC4 expression is measured. Determine whether ZIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and ZIC4 expression is measured. Determine whether ZIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2619
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of SLC43A2. Does this perturbation cause a significant change in SLC43A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of SLC43A2. Does this perturbation cause a significant change in SLC43A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1534
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Determine whether IL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Determine whether IL20 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3766
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor RABAC1 expression. Decide whether this perturbation leads to a significant alteration in RABAC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor RABAC1 expression. Decide whether this perturbation leads to a significant alteration in RABAC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5148
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of XX-FW83563B9.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of XX-FW83563B9.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3297
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-259K5.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in RP11-259K5.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1245
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and IGHEP2 expression is measured. Determine whether IGHEP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and IGHEP2 expression is measured. Determine whether IGHEP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3589
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5508
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":670
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Determine whether TXNIP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4696
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Does this perturbation cause a significant change in VCX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Does this perturbation cause a significant change in VCX3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":150
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Determine whether ZC3HAV1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4976
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MBP expression is quantified. Does this perturbation result in a significant change in MBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and MBP expression is quantified. Does this perturbation result in a significant change in MBP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1002
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and TEX30 expression is quantified. Does this perturbation result in a significant change in TEX30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and TEX30 expression is quantified. Does this perturbation result in a significant change in TEX30 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2412
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is measured. Determine whether RP11-109E24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-109E24.2 expression is measured. Determine whether RP11-109E24.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6219
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of FABP5. Does perturbing SGK1 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of FABP5. Does perturbing SGK1 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4041
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor PRKAG2-AS1 expression. Decide whether this perturbation leads to a significant alteration in PRKAG2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor PRKAG2-AS1 expression. Decide whether this perturbation leads to a significant alteration in PRKAG2-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3168
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of AC145110.1. Does this perturbation cause a significant change in AC145110.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of AC145110.1. Does this perturbation cause a significant change in AC145110.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3114
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3715
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Does this perturbation cause a significant change in S100A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Does this perturbation cause a significant change in S100A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1750
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Does this perturbation cause a significant change in WDR88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Does this perturbation cause a significant change in WDR88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4720
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1387
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor IFIT2 expression. Decide whether this perturbation leads to a significant alteration in IFIT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor IFIT2 expression. Decide whether this perturbation leads to a significant alteration in IFIT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6028
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3627
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of C17orf64 is measured. Does this perturbation cause a significant change in C17orf64 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1710
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of AC006262.5. Does perturbing TMSB4X lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of AC006262.5. Does perturbing TMSB4X lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4521
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and RP11-442O1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-442O1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and RP11-442O1.4 expression is observed. Does this perturbation lead to a significant difference in RP11-442O1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4663
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Does this perturbation cause a significant change in CCNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of CCNB1 is measured. Does this perturbation cause a significant change in CCNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3850
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5400
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of TXNIP is measured. Does this perturbation cause a significant change in TXNIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4690
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is quantified. Does this perturbation result in a significant change in RP6-159A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is quantified. Does this perturbation result in a significant change in RP6-159A1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2822
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in C1orf228 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in C1orf228 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1115
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6234
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in SCG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in SCG5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5855
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":798
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and SLC22A13 expression is measured. Determine whether SLC22A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and SLC22A13 expression is measured. Determine whether SLC22A13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4009
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and FLJ12825 expression is measured. Determine whether FLJ12825 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and FLJ12825 expression is measured. Determine whether FLJ12825 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":179
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-290K4.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290K4.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP11-290K4.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290K4.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3703
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and NCALD expression is observed. Does this perturbation lead to a significant difference in NCALD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and NCALD expression is observed. Does this perturbation lead to a significant difference in NCALD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4833
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CTD-2031P19.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CTD-2031P19.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":887
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5838
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ACP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in ACP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1205
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in CCR10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1865
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5704
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is measured. Determine whether RP11-497G19.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is measured. Determine whether RP11-497G19.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1259
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3003
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and AC007193.6 expression is observed. Does this perturbation lead to a significant difference in AC007193.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and AC007193.6 expression is observed. Does this perturbation lead to a significant difference in AC007193.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2633
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of CISH is measured. Determine whether CISH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2586
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Determine whether CST3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2746
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Determine whether LEFTY1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of LEFTY1 is measured. Determine whether LEFTY1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5916
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of AC144568.2. Does perturbing KLF1 lead to a significant change in AC144568.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of AC144568.2. Does perturbing KLF1 lead to a significant change in AC144568.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":591
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of CCNB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of CCNB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4337
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in SLC8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in SLC8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4555
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2587
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2228
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4767
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP6-159A1.4. Does perturbing MAPK1 lead to a significant change in RP6-159A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of RP6-159A1.4. Does perturbing MAPK1 lead to a significant change in RP6-159A1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2821
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of COL18A1-AS1. Does perturbing BAK1 lead to a significant change in COL18A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BAK1 and examine the expression of COL18A1-AS1. Does perturbing BAK1 lead to a significant change in COL18A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":631
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of AVP. Does perturbing IKZF3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of AVP. Does perturbing IKZF3 lead to a significant change in AVP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3001
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1184
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Does this perturbation cause a significant change in AC007556.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Does this perturbation cause a significant change in AC007556.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":820
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ATP8A1 expression is observed. Does this perturbation lead to a significant difference in ATP8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ATP8A1 expression is observed. Does this perturbation lead to a significant difference in ATP8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3523
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-259K5.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-259K5.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-259K5.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-259K5.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1248
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Does this perturbation cause a significant change in TFRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Does this perturbation cause a significant change in TFRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1220
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of SLC4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of SLC4A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6087
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of KRT7. Does perturbing FOSB lead to a significant change in KRT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of KRT7. Does perturbing FOSB lead to a significant change in KRT7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2791
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Determine whether RNF168 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Determine whether RNF168 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":776
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3198
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of PNMT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":377
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLA2G1B expression. Decide whether this perturbation leads to a significant alteration in PLA2G1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLA2G1B expression. Decide whether this perturbation leads to a significant alteration in PLA2G1B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":758
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ATP9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ATP9A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":537
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of MFGE8 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2487
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in NUCB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in NUCB2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3135
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor UCKL1-AS1 expression. Decide whether this perturbation leads to a significant alteration in UCKL1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor UCKL1-AS1 expression. Decide whether this perturbation leads to a significant alteration in UCKL1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5258
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCDC148 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in CCDC148 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2135
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and TRAPPC3L expression is measured. Determine whether TRAPPC3L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and TRAPPC3L expression is measured. Determine whether TRAPPC3L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6259
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2585
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":556
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-128B16.3. Does perturbing AHR lead to a significant change in RP11-128B16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-128B16.3. Does perturbing AHR lead to a significant change in RP11-128B16.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1791
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CACNA1C-AS2 is measured. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":350
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-128B16.3 expression is quantified. Does this perturbation result in a significant change in RP11-128B16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-128B16.3 expression is quantified. Does this perturbation result in a significant change in RP11-128B16.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1792
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and STRC expression is quantified. Does this perturbation result in a significant change in STRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and STRC expression is quantified. Does this perturbation result in a significant change in STRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5902
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":80
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ADGB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of ADGB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5547
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Does this perturbation cause a significant change in RP11-202A13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of RP11-202A13.1 is measured. Does this perturbation cause a significant change in RP11-202A13.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4780
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2608
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and PRTN3 expression is measured. Determine whether PRTN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and PRTN3 expression is measured. Determine whether PRTN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1109
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of RP11-635N19.1. Does this perturbation cause a significant change in RP11-635N19.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of RP11-635N19.1. Does this perturbation cause a significant change in RP11-635N19.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1374
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1164
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2952
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and SLC7A11 expression is measured. Determine whether SLC7A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and SLC7A11 expression is measured. Determine whether SLC7A11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4899
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ZMYND15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of ZMYND15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2737
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5702
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and MCC expression is quantified. Does this perturbation result in a significant change in MCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and MCC expression is quantified. Does this perturbation result in a significant change in MCC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3512
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4262
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RP11-285F7.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-285F7.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RP11-285F7.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-285F7.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4908
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of FILIP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of FILIP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2267
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5709
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Does this perturbation cause a significant change in REEP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Does this perturbation cause a significant change in REEP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2000
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of TMEM154. Does this perturbation cause a significant change in TMEM154 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of TMEM154. Does this perturbation cause a significant change in TMEM154 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4144
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and SOX4 expression is measured. Determine whether SOX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and SOX4 expression is measured. Determine whether SOX4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2359
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4817
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor CD9 expression. Decide whether this perturbation leads to a significant alteration in CD9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3748
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Does this perturbation cause a significant change in RLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of RLN3 is measured. Does this perturbation cause a significant change in RLN3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5000
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of RABGAP1L. Does this perturbation cause a significant change in RABGAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":484
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ZNF677. Does perturbing HOXB9 lead to a significant change in ZNF677 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of ZNF677. Does perturbing HOXB9 lead to a significant change in ZNF677 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3091
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of C10orf11. Does perturbing FEV lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of C10orf11. Does perturbing FEV lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":671
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and EGOT expression is observed. Does this perturbation lead to a significant difference in EGOT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and EGOT expression is observed. Does this perturbation lead to a significant difference in EGOT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5673
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of ZMAT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5137
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and AFMID expression is observed. Does this perturbation lead to a significant difference in AFMID expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5503
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of PHGDH is measured. Determine whether PHGDH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4506
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of CTSS. Does this perturbation cause a significant change in CTSS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of CTSS. Does this perturbation cause a significant change in CTSS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2024
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4577
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Does this perturbation cause a significant change in UBASH3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1400
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of RABGAP1L. Does perturbing ZBTB1 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of RABGAP1L. Does perturbing ZBTB1 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3551
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is measured. Determine whether RP11-355B11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and RP11-355B11.2 expression is measured. Determine whether RP11-355B11.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1179
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and MSRB1 expression is observed. Does this perturbation lead to a significant difference in MSRB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and MSRB1 expression is observed. Does this perturbation lead to a significant difference in MSRB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2653
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and FMNL1 expression is quantified. Does this perturbation result in a significant change in FMNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and FMNL1 expression is quantified. Does this perturbation result in a significant change in FMNL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1692
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-1017G21.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-1017G21.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-1017G21.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-1017G21.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3828
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and SLC4A3 expression is measured. Determine whether SLC4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and SLC4A3 expression is measured. Determine whether SLC4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6089
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor MT1E expression. Decide whether this perturbation leads to a significant alteration in MT1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor MT1E expression. Decide whether this perturbation leads to a significant alteration in MT1E expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":368
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":800
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of CTC-490E21.10. Does this perturbation cause a significant change in CTC-490E21.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of CTC-490E21.10. Does this perturbation cause a significant change in CTC-490E21.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":574
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Determine whether RP11-563J2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-563J2.3 is measured. Determine whether RP11-563J2.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3816
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":918
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in TNFAIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in TNFAIP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5205
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AIF1. Does perturbing MAP4K3 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AIF1. Does perturbing MAP4K3 lead to a significant change in AIF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2281
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and KRT7 expression is measured. Determine whether KRT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and KRT7 expression is measured. Determine whether KRT7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2799
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2484
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of XK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of XK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2627
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CENPE. Does this perturbation cause a significant change in CENPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CENPE. Does this perturbation cause a significant change in CENPE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6224
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2953
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Determine whether XX-FW83563B9.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of XX-FW83563B9.5 is measured. Determine whether XX-FW83563B9.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3296
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor CCDC136 expression. Decide whether this perturbation leads to a significant alteration in CCDC136 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor CCDC136 expression. Decide whether this perturbation leads to a significant alteration in CCDC136 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5038
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCDC148 expression is measured. Determine whether CCDC148 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCDC148 expression is measured. Determine whether CCDC148 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2139
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ARPC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ARPC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":847
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":853
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5706
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of RP1-102K2.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1017
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in FLJ12825 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in FLJ12825 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":175
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and DSC1 expression is measured. Determine whether DSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and DSC1 expression is measured. Determine whether DSC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1299
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of CCR10 is measured. Determine whether CCR10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1486
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4103
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CD37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CD37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3245
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CARMN expression. Decide whether this perturbation leads to a significant alteration in CARMN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CARMN expression. Decide whether this perturbation leads to a significant alteration in CARMN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3278
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PRSS57. Does perturbing ZNF318 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PRSS57. Does perturbing ZNF318 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1151
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Does this perturbation cause a significant change in C8orf22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C8orf22 is measured. Does this perturbation cause a significant change in C8orf22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1890
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LRRC74B. Does this perturbation cause a significant change in LRRC74B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LRRC74B. Does this perturbation cause a significant change in LRRC74B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4654
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and TOR3A expression is quantified. Does this perturbation result in a significant change in TOR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and TOR3A expression is quantified. Does this perturbation result in a significant change in TOR3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5342
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of TRPM2. Does perturbing UBASH3B lead to a significant change in TRPM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of TRPM2. Does perturbing UBASH3B lead to a significant change in TRPM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1421
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and AC016629.3 expression is observed. Does this perturbation lead to a significant difference in AC016629.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3613
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNX1. Does this perturbation cause a significant change in RUNX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2784
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PAQR7. Does perturbing ZNF318 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of PAQR7. Does perturbing ZNF318 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1181
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in TDRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in TDRD12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":95
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in BCL2L11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in BCL2L11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4925
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RHOH. Does this perturbation cause a significant change in RHOH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RHOH. Does this perturbation cause a significant change in RHOH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4454
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and ACE expression is quantified. Does this perturbation result in a significant change in ACE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3652
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and COL21A1 expression is quantified. Does this perturbation result in a significant change in COL21A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and COL21A1 expression is quantified. Does this perturbation result in a significant change in COL21A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4422
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Does this perturbation cause a significant change in AREG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of AREG is measured. Does this perturbation cause a significant change in AREG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2500
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and TOX expression is quantified. Does this perturbation result in a significant change in TOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and TOX expression is quantified. Does this perturbation result in a significant change in TOX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1362
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and MYL4 expression is observed. Does this perturbation lead to a significant difference in MYL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and MYL4 expression is observed. Does this perturbation lead to a significant difference in MYL4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5563
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1569
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-259K5.1. Does perturbing COL2A1 lead to a significant change in RP11-259K5.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-259K5.1. Does perturbing COL2A1 lead to a significant change in RP11-259K5.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1241
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and PCDHGA3 expression is observed. Does this perturbation lead to a significant difference in PCDHGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and PCDHGA3 expression is observed. Does this perturbation lead to a significant difference in PCDHGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2563
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of RGS16 is measured. Does this perturbation cause a significant change in RGS16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":210
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and LINC01342 expression is measured. Determine whether LINC01342 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and LINC01342 expression is measured. Determine whether LINC01342 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2209
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Determine whether SNCG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Determine whether SNCG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1986
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HCN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of HCN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3047
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HHEX. Does perturbing SAMD1 lead to a significant change in HHEX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of HHEX. Does perturbing SAMD1 lead to a significant change in HHEX expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3381
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RP3-467K16.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1477
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and AC145110.1 expression is observed. Does this perturbation lead to a significant difference in AC145110.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and AC145110.1 expression is observed. Does this perturbation lead to a significant difference in AC145110.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3113
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of MYB. Does this perturbation cause a significant change in MYB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of MYB. Does this perturbation cause a significant change in MYB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2104
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of SLC22A13. Does perturbing MAP2K6 lead to a significant change in SLC22A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of SLC22A13. Does perturbing MAP2K6 lead to a significant change in SLC22A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4001
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1862
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SLC20A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SLC20A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2407
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and HIST1H3H expression is measured. Determine whether HIST1H3H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and HIST1H3H expression is measured. Determine whether HIST1H3H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5339
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and TPH2 expression is measured. Determine whether TPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and TPH2 expression is measured. Determine whether TPH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3419
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of KIF2C. Does perturbing KIF2C lead to a significant change in KIF2C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4561
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and SCG5 expression is quantified. Does this perturbation result in a significant change in SCG5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and SCG5 expression is quantified. Does this perturbation result in a significant change in SCG5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5852
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and KIF2C expression is quantified. Does this perturbation result in a significant change in KIF2C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4562
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and CD46 expression is quantified. Does this perturbation result in a significant change in CD46 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4202
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor SPTAN1 expression. Decide whether this perturbation leads to a significant alteration in SPTAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor SPTAN1 expression. Decide whether this perturbation leads to a significant alteration in SPTAN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2168
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Determine whether KIAA2012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of KIAA2012 is measured. Determine whether KIAA2012 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":116
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ATP8B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in ATP8B4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1555
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":968
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of WBP2. Does perturbing CBFA2T3 lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of WBP2. Does perturbing CBFA2T3 lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1651
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and PERM1 expression is quantified. Does this perturbation result in a significant change in PERM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and PERM1 expression is quantified. Does this perturbation result in a significant change in PERM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5482
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1950
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of SEMA3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of SEMA3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4247
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01227. Does this perturbation cause a significant change in LINC01227 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01227. Does this perturbation cause a significant change in LINC01227 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5434
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and RCSD1 expression is quantified. Does this perturbation result in a significant change in RCSD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1442
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1320
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ACP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of ACP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1207
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Does this perturbation cause a significant change in COL18A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Does this perturbation cause a significant change in COL18A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":630
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Determine whether CTD-2527I21.14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Determine whether CTD-2527I21.14 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4416
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and MFGE8 expression is measured. Determine whether MFGE8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5949
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and SLC8A1 expression is measured. Determine whether SLC8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and SLC8A1 expression is measured. Determine whether SLC8A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4559
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3309
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Does this perturbation cause a significant change in RP1-59D14.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Does this perturbation cause a significant change in RP1-59D14.10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3770
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in RP11-1085N6.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in RP11-1085N6.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3405
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Does this perturbation cause a significant change in SERPINF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Does this perturbation cause a significant change in SERPINF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1080
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Does this perturbation cause a significant change in RP11-714G18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Does this perturbation cause a significant change in RP11-714G18.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1850
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and FAM225B expression is measured. Determine whether FAM225B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and FAM225B expression is measured. Determine whether FAM225B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5239
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Does this perturbation cause a significant change in CTB-49A3.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of CTB-49A3.5 is measured. Does this perturbation cause a significant change in CTB-49A3.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3390
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor REEP6 expression. Decide whether this perturbation leads to a significant alteration in REEP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor REEP6 expression. Decide whether this perturbation leads to a significant alteration in REEP6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2008
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CTD-2031P19.5. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CTD-2031P19.5. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":884
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-505P4.7. Does this perturbation cause a significant change in RP11-505P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of RP11-505P4.7. Does this perturbation cause a significant change in RP11-505P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2554
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and LEFTY1 expression is quantified. Does this perturbation result in a significant change in LEFTY1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and LEFTY1 expression is quantified. Does this perturbation result in a significant change in LEFTY1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5912
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3452
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Does this perturbation cause a significant change in SH3BGRL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Does this perturbation cause a significant change in SH3BGRL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":390
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of N4BP2L2. Does perturbing CEBPA lead to a significant change in N4BP2L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of N4BP2L2. Does perturbing CEBPA lead to a significant change in N4BP2L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4221
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in CALY expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in CALY expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1595
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Determine whether RP11-355B11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Determine whether RP11-355B11.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1176
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of KIAA2012. Does this perturbation cause a significant change in KIAA2012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of KIAA2012. Does this perturbation cause a significant change in KIAA2012 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":114
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of EGOT. Does this perturbation cause a significant change in EGOT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of EGOT. Does this perturbation cause a significant change in EGOT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5674
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of CLU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of CLU indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":17
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2043
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ATP10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ATP10D expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2925
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3847
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Determine whether CARMN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of CARMN is measured. Determine whether CARMN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3276
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2747
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Determine whether AKAP13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Determine whether AKAP13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3986
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of KCNH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of KCNH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3447
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5810
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Determine whether RP11-442O1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Determine whether RP11-442O1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4666
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor SIGLEC15 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor SIGLEC15 expression. Decide whether this perturbation leads to a significant alteration in SIGLEC15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1968
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PAMR1. Does perturbing CNNM4 lead to a significant change in PAMR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PAMR1. Does perturbing CNNM4 lead to a significant change in PAMR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4791
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RHOH expression is quantified. Does this perturbation result in a significant change in RHOH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RHOH expression is quantified. Does this perturbation result in a significant change in RHOH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4452
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of RP11-445F12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of RP11-445F12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":607
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Determine whether LINC01420 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Determine whether LINC01420 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5426
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of TAS1R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of TAS1R1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":707
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ID3. Does perturbing ELMSAN1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of ID3. Does perturbing ELMSAN1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":241
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor C17orf64 expression. Decide whether this perturbation leads to a significant alteration in C17orf64 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1718
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5262
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Does this perturbation cause a significant change in RP11-1085N6.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3400
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is measured. Determine whether RP6-159A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and RP6-159A1.4 expression is measured. Determine whether RP6-159A1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2829
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ACE. Does this perturbation cause a significant change in ACE expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3654
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SLC20A1. Does this perturbation cause a significant change in SLC20A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SLC20A1. Does this perturbation cause a significant change in SLC20A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2404
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Does this perturbation cause a significant change in PCDHGA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PCDHGA6 is measured. Does this perturbation cause a significant change in PCDHGA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1300
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor PPP4R4 expression. Decide whether this perturbation leads to a significant alteration in PPP4R4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor PPP4R4 expression. Decide whether this perturbation leads to a significant alteration in PPP4R4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4618
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor LINC01003 expression. Decide whether this perturbation leads to a significant alteration in LINC01003 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor LINC01003 expression. Decide whether this perturbation leads to a significant alteration in LINC01003 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":458
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5452
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and DEK expression is observed. Does this perturbation lead to a significant difference in DEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and DEK expression is observed. Does this perturbation lead to a significant difference in DEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1673
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ZMYND15 expression is observed. Does this perturbation lead to a significant difference in ZMYND15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and ZMYND15 expression is observed. Does this perturbation lead to a significant difference in ZMYND15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2733
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in TFAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in TFAP2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2315
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of COTL1. Does perturbing ZBTB25 lead to a significant change in COTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of COTL1. Does perturbing ZBTB25 lead to a significant change in COTL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1281
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in AC004540.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in AC004540.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4125
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and GCM2 expression is measured. Determine whether GCM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and GCM2 expression is measured. Determine whether GCM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1359
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Determine whether CTC-490E21.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of CTC-490E21.10 is measured. Determine whether CTC-490E21.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":576
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01227 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01227 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5435
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3577
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and KCNH2 expression is quantified. Does this perturbation result in a significant change in KCNH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and KCNH2 expression is quantified. Does this perturbation result in a significant change in KCNH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3442
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Determine whether PRTN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of PRTN3 is measured. Determine whether PRTN3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1106
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":489
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor CCR10 expression. Decide whether this perturbation leads to a significant alteration in CCR10 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1868
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3439
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":960
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and KCNH2 expression is observed. Does this perturbation lead to a significant difference in KCNH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and KCNH2 expression is observed. Does this perturbation lead to a significant difference in KCNH2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3443
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and MCC expression is measured. Determine whether MCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and MCC expression is measured. Determine whether MCC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3519
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and AIM1 expression is quantified. Does this perturbation result in a significant change in AIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and AIM1 expression is quantified. Does this perturbation result in a significant change in AIM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3122
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5688
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM83F expression is quantified. Does this perturbation result in a significant change in FAM83F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and FAM83F expression is quantified. Does this perturbation result in a significant change in FAM83F expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2682
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Determine whether TDRD12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of TDRD12 is measured. Determine whether TDRD12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":96
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and UBASH3A expression is observed. Does this perturbation lead to a significant difference in UBASH3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4823
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CTD-3126B10.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3126B10.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CTD-3126B10.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3126B10.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2398
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of GRAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of GRAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":317
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ISL2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4472
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6054
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in CLTA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in CLTA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3995
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6100
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RABGAP1L expression is observed. Does this perturbation lead to a significant difference in RABGAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":483
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Determine whether CHST15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Determine whether CHST15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2496
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in CISH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3605
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and GRAP2 expression is measured. Determine whether GRAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and GRAP2 expression is measured. Determine whether GRAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":319
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of CTD-2616J11.16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of CTD-2616J11.16 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1197
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is quantified. Does this perturbation result in a significant change in RP11-968A15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is quantified. Does this perturbation result in a significant change in RP11-968A15.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":832
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SAT1 expression. Decide whether this perturbation leads to a significant alteration in SAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SAT1 expression. Decide whether this perturbation leads to a significant alteration in SAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1808
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Determine whether SLC2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Determine whether SLC2A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2536
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RP11-320G24.1. Does perturbing OSR2 lead to a significant change in RP11-320G24.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RP11-320G24.1. Does perturbing OSR2 lead to a significant change in RP11-320G24.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5061
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PTRF. Does perturbing SLC4A1 lead to a significant change in PTRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PTRF. Does perturbing SLC4A1 lead to a significant change in PTRF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1031
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and TNFAIP2 expression is observed. Does this perturbation lead to a significant difference in TNFAIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and TNFAIP2 expression is observed. Does this perturbation lead to a significant difference in TNFAIP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5203
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in RELB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in RELB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5655
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2845
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor TNFAIP8 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor TNFAIP8 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2188
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5020
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor INADL expression. Decide whether this perturbation leads to a significant alteration in INADL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K3 and monitor INADL expression. Decide whether this perturbation leads to a significant alteration in INADL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2258
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of AP1S2. Does perturbing CEBPA lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of AP1S2. Does perturbing CEBPA lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4211
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":20
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor MAP7D1 expression. Decide whether this perturbation leads to a significant alteration in MAP7D1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2728
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of HEATR9. Does this perturbation cause a significant change in HEATR9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of HEATR9. Does this perturbation cause a significant change in HEATR9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2384
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2955
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of RP11-91A18.4. Does this perturbation cause a significant change in RP11-91A18.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of RP11-91A18.4. Does this perturbation cause a significant change in RP11-91A18.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2694
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ST3GAL5 expression is measured. Determine whether ST3GAL5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and ST3GAL5 expression is measured. Determine whether ST3GAL5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1769
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP6-159A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP6-159A1.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2827
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and HBD expression is measured. Determine whether HBD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4819
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of RP11-369K17.1. Does this perturbation cause a significant change in RP11-369K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of RP11-369K17.1. Does this perturbation cause a significant change in RP11-369K17.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5474
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1819
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4689
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of RETN. Does perturbing PTPN1 lead to a significant change in RETN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of RETN. Does perturbing PTPN1 lead to a significant change in RETN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2451
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of TDRD12. Does perturbing MAML2 lead to a significant change in TDRD12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of TDRD12. Does perturbing MAML2 lead to a significant change in TDRD12 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":91
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ADGB expression. Decide whether this perturbation leads to a significant alteration in ADGB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor ADGB expression. Decide whether this perturbation leads to a significant alteration in ADGB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5548
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CD59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CD59 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2375
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AC006262.5. Does perturbing SLC38A2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AC006262.5. Does perturbing SLC38A2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5681
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Does this perturbation cause a significant change in RP11-195C7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Does this perturbation cause a significant change in RP11-195C7.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1730
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in CTB-161C1.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1415
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and PYROXD2 expression is quantified. Does this perturbation result in a significant change in PYROXD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5152
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of SPTAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of SPTAN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2167
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and CCNJL expression is quantified. Does this perturbation result in a significant change in CCNJL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and CCNJL expression is quantified. Does this perturbation result in a significant change in CCNJL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5122
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and TYROBP expression is measured. Determine whether TYROBP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5089
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and HSD17B4 expression is quantified. Does this perturbation result in a significant change in HSD17B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and HSD17B4 expression is quantified. Does this perturbation result in a significant change in HSD17B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":142
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AC007246.3 expression is observed. Does this perturbation lead to a significant difference in AC007246.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AC007246.3 expression is observed. Does this perturbation lead to a significant difference in AC007246.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2293
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of RGS16. Does this perturbation cause a significant change in RGS16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":214
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of HOGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of HOGA1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2867
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and ZFP36L2 expression is measured. Determine whether ZFP36L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3679
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Determine whether FAM83A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Determine whether FAM83A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5626
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CD46 expression. Decide whether this perturbation leads to a significant alteration in CD46 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4208
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of CTNNB1. Does this perturbation cause a significant change in CTNNB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":504
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of STAC3. Does perturbing ELMSAN1 lead to a significant change in STAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of STAC3. Does perturbing ELMSAN1 lead to a significant change in STAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":271
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of PNMT. Does perturbing BCORL1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of PNMT. Does perturbing BCORL1 lead to a significant change in PNMT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":371
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":53
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1644
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Determine whether FAM101B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":306
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is quantified. Does this perturbation result in a significant change in SIGLEC15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is quantified. Does this perturbation result in a significant change in SIGLEC15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1962
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RP11-320G24.1. Does this perturbation cause a significant change in RP11-320G24.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of RP11-320G24.1. Does this perturbation cause a significant change in RP11-320G24.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5064
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor MSRB1 expression. Decide whether this perturbation leads to a significant alteration in MSRB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor MSRB1 expression. Decide whether this perturbation leads to a significant alteration in MSRB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2658
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of TYROBP. Does perturbing ETS2 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of TYROBP. Does perturbing ETS2 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":791
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and NUMB expression is observed. Does this perturbation lead to a significant difference in NUMB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and NUMB expression is observed. Does this perturbation lead to a significant difference in NUMB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3263
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and CPVL expression is quantified. Does this perturbation result in a significant change in CPVL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCL2L11 is perturbed and CPVL expression is quantified. Does this perturbation result in a significant change in CPVL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4932
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of AC006262.5. Does perturbing KIF2C lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of AC006262.5. Does perturbing KIF2C lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4571
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Determine whether CPVL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of CPVL is measured. Determine whether CPVL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4936
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6136
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of CLTA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of CLTA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3997
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and C19orf38 expression is measured. Determine whether C19orf38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and C19orf38 expression is measured. Determine whether C19orf38 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4849
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Determine whether ANXA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Determine whether ANXA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2836
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of SLC22A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of SLC22A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4007
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of RAB5B. Does this perturbation cause a significant change in RAB5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of RAB5B. Does this perturbation cause a significant change in RAB5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":684
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3197
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is measured. Determine whether CTD-2012K14.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and CTD-2012K14.6 expression is measured. Determine whether CTD-2012K14.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5219
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of HBG1. Does perturbing CDKN1B lead to a significant change in HBG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of HBG1. Does perturbing CDKN1B lead to a significant change in HBG1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5381
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and SIGLEC15 expression is observed. Does this perturbation lead to a significant difference in SIGLEC15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and SIGLEC15 expression is observed. Does this perturbation lead to a significant difference in SIGLEC15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1963
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of ZEB2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3207
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FCER1G expression is quantified. Does this perturbation result in a significant change in FCER1G expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5642
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of RP1-261G23.7. Does this perturbation cause a significant change in RP1-261G23.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of RP1-261G23.7. Does this perturbation cause a significant change in RP1-261G23.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1904
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Determine whether KRT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Determine whether KRT7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2796
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5685
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of INADL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of INADL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2257
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and HERPUD1 expression is observed. Does this perturbation lead to a significant difference in HERPUD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5823
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ATP10D expression is measured. Determine whether ATP10D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ATP10D expression is measured. Determine whether ATP10D exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2929
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4573
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Does this perturbation cause a significant change in CTA-384D8.34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of CTA-384D8.34 is measured. Does this perturbation cause a significant change in CTA-384D8.34 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":640
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and NCKAP1L expression is measured. Determine whether NCKAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3089
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ARRDC3. Does perturbing DUSP9 lead to a significant change in ARRDC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of ARRDC3. Does perturbing DUSP9 lead to a significant change in ARRDC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":231
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of IFIT2. Does perturbing PRDM1 lead to a significant change in IFIT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of IFIT2. Does perturbing PRDM1 lead to a significant change in IFIT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6021
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4982
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2589
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ZNF610 expression is measured. Determine whether ZNF610 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and ZNF610 expression is measured. Determine whether ZNF610 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2439
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and VMP1 expression is observed. Does this perturbation lead to a significant difference in VMP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and VMP1 expression is observed. Does this perturbation lead to a significant difference in VMP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5863
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":745
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6099
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CTD-2311M21.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CTD-2311M21.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":405
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Determine whether ZNF677 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of ZNF677 is measured. Determine whether ZNF677 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3096
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is measured. Determine whether KCNQ1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and KCNQ1-AS1 expression is measured. Determine whether KCNQ1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5119
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Does this perturbation cause a significant change in AIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of AIM1 is measured. Does this perturbation cause a significant change in AIM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3120
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4465
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4542
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CHP1 expression is quantified. Does this perturbation result in a significant change in CHP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TGFBR2 is perturbed and CHP1 expression is quantified. Does this perturbation result in a significant change in CHP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5462
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in TEX30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in TEX30 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2415
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and AREG expression is measured. Determine whether AREG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and AREG expression is measured. Determine whether AREG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2509
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in MYB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in MYB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2105
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2467
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MS4A3 expression is measured. Determine whether MS4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and MS4A3 expression is measured. Determine whether MS4A3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":989
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor COL1A1 expression. Decide whether this perturbation leads to a significant alteration in COL1A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor COL1A1 expression. Decide whether this perturbation leads to a significant alteration in COL1A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5058
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor SSTR3 expression. Decide whether this perturbation leads to a significant alteration in SSTR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor SSTR3 expression. Decide whether this perturbation leads to a significant alteration in SSTR3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3178
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and BMP2K expression is observed. Does this perturbation lead to a significant difference in BMP2K expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and BMP2K expression is observed. Does this perturbation lead to a significant difference in BMP2K expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1503
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CTD-2311M21.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2311M21.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and CTD-2311M21.3 expression is observed. Does this perturbation lead to a significant difference in CTD-2311M21.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":403
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and SPTAN1 expression is quantified. Does this perturbation result in a significant change in SPTAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and SPTAN1 expression is quantified. Does this perturbation result in a significant change in SPTAN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2162
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and RP11-286H15.1 expression is observed. Does this perturbation lead to a significant difference in RP11-286H15.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and RP11-286H15.1 expression is observed. Does this perturbation lead to a significant difference in RP11-286H15.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2513
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6186
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor HOXB6 expression. Decide whether this perturbation leads to a significant alteration in HOXB6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor HOXB6 expression. Decide whether this perturbation leads to a significant alteration in HOXB6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":818
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLA2G1B. Does perturbing CBL lead to a significant change in PLA2G1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of PLA2G1B. Does perturbing CBL lead to a significant change in PLA2G1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":751
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is measured. Determine whether CTA-384D8.34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is measured. Determine whether CTA-384D8.34 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":649
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-52L5.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of RP11-52L5.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6207
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Determine whether RIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RIT1 is measured. Determine whether RIT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4916
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of MKNK2. Does perturbing CBFA2T3 lead to a significant change in MKNK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of MKNK2. Does perturbing CBFA2T3 lead to a significant change in MKNK2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1621
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ID3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3485
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in AMHR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6105
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1333
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Determine whether PERM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Determine whether PERM1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5486
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is quantified. Does this perturbation result in a significant change in CTD-3131K8.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is quantified. Does this perturbation result in a significant change in CTD-3131K8.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2752
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and LBH expression is quantified. Does this perturbation result in a significant change in LBH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and LBH expression is quantified. Does this perturbation result in a significant change in LBH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5932
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Determine whether HEMGN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":256
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor CST3 expression. Decide whether this perturbation leads to a significant alteration in CST3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2748
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of SSTR3. Does perturbing HOXC13 lead to a significant change in SSTR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of SSTR3. Does perturbing HOXC13 lead to a significant change in SSTR3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3171
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-52L5.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in RP11-52L5.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6205
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Does this perturbation cause a significant change in CTNNB1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":500
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and C1orf162 expression is observed. Does this perturbation lead to a significant difference in C1orf162 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and C1orf162 expression is observed. Does this perturbation lead to a significant difference in C1orf162 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3533
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of CCNB2. Does perturbing KMT2A lead to a significant change in CCNB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of CCNB2. Does perturbing KMT2A lead to a significant change in CCNB2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4331
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":915
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and AK8 expression is quantified. Does this perturbation result in a significant change in AK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and AK8 expression is quantified. Does this perturbation result in a significant change in AK8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4392
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ABCA6 expression. Decide whether this perturbation leads to a significant alteration in ABCA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ABCA6 expression. Decide whether this perturbation leads to a significant alteration in ABCA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4178
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5267
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and PTPRS expression is measured. Determine whether PTPRS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and PTPRS expression is measured. Determine whether PTPRS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":669
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor PSMB8 expression. Decide whether this perturbation leads to a significant alteration in PSMB8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor PSMB8 expression. Decide whether this perturbation leads to a significant alteration in PSMB8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":108
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Does this perturbation cause a significant change in RGPD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Does this perturbation cause a significant change in RGPD5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5960
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of CSF3R. Does perturbing ZBTB10 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of CSF3R. Does perturbing ZBTB10 lead to a significant change in CSF3R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5571
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Determine whether ADD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Determine whether ADD3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2906
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in CD9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3745
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4674
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1180
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01227. Does perturbing CDKN1B lead to a significant change in LINC01227 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of LINC01227. Does perturbing CDKN1B lead to a significant change in LINC01227 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5431
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CCNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CCNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3855
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":494
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2957
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and MOGAT2 expression is measured. Determine whether MOGAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and MOGAT2 expression is measured. Determine whether MOGAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5539
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of NCKAP1L. Does this perturbation cause a significant change in NCKAP1L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3084
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Does this perturbation cause a significant change in SNCG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SNCG is measured. Does this perturbation cause a significant change in SNCG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1980
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Does this perturbation cause a significant change in HCAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Does this perturbation cause a significant change in HCAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5190
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Determine whether CTSW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Determine whether CTSW shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5366
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is quantified. Does this perturbation result in a significant change in RP11-244F12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is quantified. Does this perturbation result in a significant change in RP11-244F12.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4532
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in MARCKS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in MARCKS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4995
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TM6SF2. Does this perturbation cause a significant change in TM6SF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4374
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3878
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ABCA6 expression is quantified. Does this perturbation result in a significant change in ABCA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ABCA6 expression is quantified. Does this perturbation result in a significant change in ABCA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4172
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of BTG2. Does this perturbation cause a significant change in BTG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1464
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and C1orf228 expression is measured. Determine whether C1orf228 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and C1orf228 expression is measured. Determine whether C1orf228 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1119
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and FAM225B expression is observed. Does this perturbation lead to a significant difference in FAM225B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and FAM225B expression is observed. Does this perturbation lead to a significant difference in FAM225B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5233
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of LEFTY2. Does this perturbation cause a significant change in LEFTY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of LEFTY2. Does this perturbation cause a significant change in LEFTY2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4944
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and AC007193.6 expression is measured. Determine whether AC007193.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and AC007193.6 expression is measured. Determine whether AC007193.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2639
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and SLC22A13 expression is observed. Does this perturbation lead to a significant difference in SLC22A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and SLC22A13 expression is observed. Does this perturbation lead to a significant difference in SLC22A13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4003
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ETS1 expression. Decide whether this perturbation leads to a significant alteration in ETS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor ETS1 expression. Decide whether this perturbation leads to a significant alteration in ETS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":588
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in FOXF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3495
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PPFIA4. Does perturbing ATL1 lead to a significant change in PPFIA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PPFIA4. Does perturbing ATL1 lead to a significant change in PPFIA4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5301
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of REEP6. Does perturbing S1PR2 lead to a significant change in REEP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of REEP6. Does perturbing S1PR2 lead to a significant change in REEP6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2001
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RABGAP1L expression. Decide whether this perturbation leads to a significant alteration in RABGAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":488
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1186
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3014
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of FOXL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3687
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ABCB11. Does this perturbation cause a significant change in ABCB11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of ABCB11. Does this perturbation cause a significant change in ABCB11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1664
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of S100A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of S100A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1757
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ALAS2. Does perturbing MAP4K3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of ALAS2. Does perturbing MAP4K3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2301
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor FCGR2A expression. Decide whether this perturbation leads to a significant alteration in FCGR2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":548
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and RNF182 expression is observed. Does this perturbation lead to a significant difference in RNF182 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and RNF182 expression is observed. Does this perturbation lead to a significant difference in RNF182 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3953
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of MTURN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of MTURN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1887
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of PDE1B. Does perturbing TSC22D1 lead to a significant change in PDE1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of PDE1B. Does perturbing TSC22D1 lead to a significant change in PDE1B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":31
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ETS1 expression is quantified. Does this perturbation result in a significant change in ETS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and ETS1 expression is quantified. Does this perturbation result in a significant change in ETS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":582
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of MFSD2A. Does perturbing HK2 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of MFSD2A. Does perturbing HK2 lead to a significant change in MFSD2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6091
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and HCAR2 expression is observed. Does this perturbation lead to a significant difference in HCAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and HCAR2 expression is observed. Does this perturbation lead to a significant difference in HCAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5193
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":742
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is quantified. Does this perturbation result in a significant change in POC1B-GALNT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and POC1B-GALNT4 expression is quantified. Does this perturbation result in a significant change in POC1B-GALNT4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1972
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and ANXA3 expression is quantified. Does this perturbation result in a significant change in ANXA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3962
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5815
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Determine whether IER3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of IER3 is measured. Determine whether IER3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2766
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in RP11-362K14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in RP11-362K14.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4185
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":565
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and AC144568.2 expression is observed. Does this perturbation lead to a significant difference in AC144568.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and AC144568.2 expression is observed. Does this perturbation lead to a significant difference in AC144568.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":593
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PHLDA2. Does perturbing SLC4A1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of PHLDA2. Does perturbing SLC4A1 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1021
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ST3GAL5 expression is observed. Does this perturbation lead to a significant difference in ST3GAL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and ST3GAL5 expression is observed. Does this perturbation lead to a significant difference in ST3GAL5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1763
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2945
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3324
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RP11-83A24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-83A24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and RP11-83A24.2 expression is observed. Does this perturbation lead to a significant difference in RP11-83A24.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":523
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Does this perturbation cause a significant change in IGHEP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Does this perturbation cause a significant change in IGHEP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3580
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and DDX58 expression is observed. Does this perturbation lead to a significant difference in DDX58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and DDX58 expression is observed. Does this perturbation lead to a significant difference in DDX58 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":223
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and YPEL3 expression is observed. Does this perturbation lead to a significant difference in YPEL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and YPEL3 expression is observed. Does this perturbation lead to a significant difference in YPEL3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5753
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of TRIM22. Does perturbing TSC22D1 lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of TRIM22. Does perturbing TSC22D1 lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":51
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RP11-320G24.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RP11-320G24.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5065
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Does this perturbation cause a significant change in CTC-492K19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Does this perturbation cause a significant change in CTC-492K19.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1120
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor MCC expression. Decide whether this perturbation leads to a significant alteration in MCC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3518
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of CISH. Does perturbing PRTG lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of CISH. Does perturbing PRTG lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3601
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and MFGE8 expression is quantified. Does this perturbation result in a significant change in MFGE8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5942
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor PRTN3 expression. Decide whether this perturbation leads to a significant alteration in PRTN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor PRTN3 expression. Decide whether this perturbation leads to a significant alteration in PRTN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1108
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":29
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Determine whether TFAP2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Determine whether TFAP2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2316
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXC13 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3158
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and PCK1 expression is observed. Does this perturbation lead to a significant difference in PCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and PCK1 expression is observed. Does this perturbation lead to a significant difference in PCK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5733
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2286
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of SPANXD. Does perturbing KIAA1804 lead to a significant change in SPANXD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of SPANXD. Does perturbing KIAA1804 lead to a significant change in SPANXD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4191
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C3orf72 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3845
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TUBB2B expression is observed. Does this perturbation lead to a significant difference in TUBB2B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1583
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in MYLIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in MYLIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1235
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4218
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of GRN. Does perturbing HOXA13 lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of GRN. Does perturbing HOXA13 lead to a significant change in GRN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5881
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of IGHEP2. Does this perturbation cause a significant change in IGHEP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of IGHEP2. Does this perturbation cause a significant change in IGHEP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3584
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6188
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Determine whether C1orf162 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Determine whether C1orf162 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3536
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of NUMB. Does perturbing CLDN6 lead to a significant change in NUMB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of NUMB. Does perturbing CLDN6 lead to a significant change in NUMB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3261
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in SLC22A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in SLC22A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4005
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of C1orf141. Does perturbing MAP4K3 lead to a significant change in C1orf141 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of C1orf141. Does perturbing MAP4K3 lead to a significant change in C1orf141 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2331
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5689
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and SLC7A11 expression is observed. Does this perturbation lead to a significant difference in SLC7A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and SLC7A11 expression is observed. Does this perturbation lead to a significant difference in SLC7A11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4893
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3303
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RCSD1. Does perturbing SLC6A9 lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RCSD1. Does perturbing SLC6A9 lead to a significant change in RCSD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1441
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of NKG7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2597
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PPFIA4 expression. Decide whether this perturbation leads to a significant alteration in PPFIA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PPFIA4 expression. Decide whether this perturbation leads to a significant alteration in PPFIA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5308
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Determine whether MME shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Determine whether MME shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6266
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Does this perturbation cause a significant change in LINC01342 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Does this perturbation cause a significant change in LINC01342 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2200
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Determine whether CTD-2311M21.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Determine whether CTD-2311M21.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":406
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ARHGEF6. Does perturbing CNN1 lead to a significant change in ARHGEF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of ARHGEF6. Does perturbing CNN1 lead to a significant change in ARHGEF6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2111
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2069
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Does this perturbation cause a significant change in ARL6IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Does this perturbation cause a significant change in ARL6IP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2930
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RUNX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of RUNX3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5957
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ACSL1. Does perturbing FOSB lead to a significant change in ACSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of ACSL1. Does perturbing FOSB lead to a significant change in ACSL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2771
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of RP11-537H15.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K3, does the expression profile of RP11-537H15.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2277
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is quantified. Does this perturbation result in a significant change in CTB-161C1.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1412
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of DEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of DEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1677
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is quantified. Does this perturbation result in a significant change in RP4-565E6.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is quantified. Does this perturbation result in a significant change in RP4-565E6.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":292
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of HIST1H4H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of HIST1H4H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4347
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM118A expression is observed. Does this perturbation lead to a significant difference in FAM118A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM118A expression is observed. Does this perturbation lead to a significant difference in FAM118A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2663
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of SKAP2. Does this perturbation cause a significant change in SKAP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":964
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and TSC22D4 expression is observed. Does this perturbation lead to a significant difference in TSC22D4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":193
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of RUNX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4687
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and CFH expression is observed. Does this perturbation lead to a significant difference in CFH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5443
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and PHGDH expression is quantified. Does this perturbation result in a significant change in PHGDH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4502
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of FCGR3A. Does this perturbation cause a significant change in FCGR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of FCGR3A. Does this perturbation cause a significant change in FCGR3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5604
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LRRC74B expression. Decide whether this perturbation leads to a significant alteration in LRRC74B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor LRRC74B expression. Decide whether this perturbation leads to a significant alteration in LRRC74B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4658
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of CTD-2616J11.16. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of CTD-2616J11.16. Does this perturbation cause a significant change in CTD-2616J11.16 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1194
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of AFMID. Does perturbing IRF1 lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of AFMID. Does perturbing IRF1 lead to a significant change in AFMID expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2961
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TPM4 expression. Decide whether this perturbation leads to a significant alteration in TPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor TPM4 expression. Decide whether this perturbation leads to a significant alteration in TPM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4518
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and MYB expression is measured. Determine whether MYB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and MYB expression is measured. Determine whether MYB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2109
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Determine whether KRT79 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of KRT79 is measured. Determine whether KRT79 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3886
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Does this perturbation cause a significant change in PLA2G1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Does this perturbation cause a significant change in PLA2G1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":750
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and AKAP13 expression is observed. Does this perturbation lead to a significant difference in AKAP13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and AKAP13 expression is observed. Does this perturbation lead to a significant difference in AKAP13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3983
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in FBXL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2525
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of ACE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3657
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Determine whether CCNG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of CCNG2 is measured. Determine whether CCNG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4066
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1925
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and AMPH expression is observed. Does this perturbation lead to a significant difference in AMPH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and AMPH expression is observed. Does this perturbation lead to a significant difference in AMPH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6013
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and AVP expression is observed. Does this perturbation lead to a significant difference in AVP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":63
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor SH3RF2 expression. Decide whether this perturbation leads to a significant alteration in SH3RF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor SH3RF2 expression. Decide whether this perturbation leads to a significant alteration in SH3RF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3238
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1589
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Determine whether RP4-550H1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Determine whether RP4-550H1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5796
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLAUR expression is observed. Does this perturbation lead to a significant difference in PLAUR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLAUR expression is observed. Does this perturbation lead to a significant difference in PLAUR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":733
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and CLTA expression is quantified. Does this perturbation result in a significant change in CLTA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K6 is perturbed and CLTA expression is quantified. Does this perturbation result in a significant change in CLTA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ZNF85 expression. Decide whether this perturbation leads to a significant alteration in ZNF85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ZNF85 expression. Decide whether this perturbation leads to a significant alteration in ZNF85 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":518
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CHP1 expression is measured. Determine whether CHP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and CHP1 expression is measured. Determine whether CHP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5469
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":432
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD9. Does perturbing BPGM lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD9. Does perturbing BPGM lead to a significant change in CD9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3741
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and HIST1H4H expression is measured. Determine whether HIST1H4H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and HIST1H4H expression is measured. Determine whether HIST1H4H exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4349
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and PSMB8 expression is observed. Does this perturbation lead to a significant difference in PSMB8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and PSMB8 expression is observed. Does this perturbation lead to a significant difference in PSMB8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":103
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1272
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2280
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ABCB11. Does perturbing CBFA2T3 lead to a significant change in ABCB11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBFA2T3 and examine the expression of ABCB11. Does perturbing CBFA2T3 lead to a significant change in ABCB11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1661
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Does this perturbation cause a significant change in HOXB6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Does this perturbation cause a significant change in HOXB6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":810
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CREB3L2. Does perturbing PRDM1 lead to a significant change in CREB3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CREB3L2. Does perturbing PRDM1 lead to a significant change in CREB3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5991
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of CTSW. Does this perturbation cause a significant change in CTSW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of CTSW. Does this perturbation cause a significant change in CTSW expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5364
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-52L5.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-52L5.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-52L5.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-52L5.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6208
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and FAM178B expression is quantified. Does this perturbation result in a significant change in FAM178B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2602
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Determine whether CTSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1096
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Does this perturbation cause a significant change in LINC00479 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Does this perturbation cause a significant change in LINC00479 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":410
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of S100A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of S100A4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1047
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ICAM4. Does this perturbation cause a significant change in ICAM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of ICAM4. Does this perturbation cause a significant change in ICAM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4744
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of NKG7. Does perturbing PTPN12 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of NKG7. Does perturbing PTPN12 lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2591
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in RP11-195B3.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in RP11-195B3.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2215
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor HMOX1 expression. Decide whether this perturbation leads to a significant alteration in HMOX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor HMOX1 expression. Decide whether this perturbation leads to a significant alteration in HMOX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5978
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-567N4.3. Does perturbing AHR lead to a significant change in RP11-567N4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of RP11-567N4.3. Does perturbing AHR lead to a significant change in RP11-567N4.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1781
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of KRT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of KRT7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2797
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CCNB1 expression. Decide whether this perturbation leads to a significant alteration in CCNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor CCNB1 expression. Decide whether this perturbation leads to a significant alteration in CCNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3858
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RP4-550H1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RP4-550H1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5795
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":7
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and PRKCB expression is measured. Determine whether PRKCB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3799
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and MMP19 expression is observed. Does this perturbation lead to a significant difference in MMP19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and MMP19 expression is observed. Does this perturbation lead to a significant difference in MMP19 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":943
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLAUR expression is measured. Determine whether PLAUR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and PLAUR expression is measured. Determine whether PLAUR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":739
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Determine whether TMEM35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Determine whether TMEM35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5016
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Does this perturbation cause a significant change in NKG7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4460
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of MFGE8. Does perturbing TBX2 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of MFGE8. Does perturbing TBX2 lead to a significant change in MFGE8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2481
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Determine whether AC078941.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of AC078941.1 is measured. Determine whether AC078941.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2016
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and PKIG expression is quantified. Does this perturbation result in a significant change in PKIG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and PKIG expression is quantified. Does this perturbation result in a significant change in PKIG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":202
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of ARHGDIB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1337
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ACTB. Does this perturbation cause a significant change in ACTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of ACTB. Does this perturbation cause a significant change in ACTB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2084
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Determine whether MCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Determine whether MCC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3516
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and MAP7D1 expression is quantified. Does this perturbation result in a significant change in MAP7D1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2722
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and NBR1 expression is quantified. Does this perturbation result in a significant change in NBR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4272
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":919
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":747
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor RP11-442O1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-442O1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor RP11-442O1.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-442O1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4668
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3433
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TM6SF2. Does perturbing TMSB4X lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TM6SF2. Does perturbing TMSB4X lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4541
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Determine whether ATP8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Determine whether ATP8A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3526
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor RP11-355B11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-355B11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor RP11-355B11.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-355B11.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1178
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RHOH expression is measured. Determine whether RHOH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RHOH expression is measured. Determine whether RHOH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4459
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is measured. Determine whether RP11-968A15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and RP11-968A15.2 expression is measured. Determine whether RP11-968A15.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":839
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6137
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1653
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4812
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is measured. Determine whether CYP1B1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is measured. Determine whether CYP1B1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4319
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Does this perturbation cause a significant change in STAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Does this perturbation cause a significant change in STAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":270
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RHOH expression. Decide whether this perturbation leads to a significant alteration in RHOH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RHOH expression. Decide whether this perturbation leads to a significant alteration in RHOH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4458
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of SLC22A11. Does perturbing HNF4A lead to a significant change in SLC22A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of SLC22A11. Does perturbing HNF4A lead to a significant change in SLC22A11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4301
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD9 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3747
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ID1. Does perturbing MAML2 lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of ID1. Does perturbing MAML2 lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":71
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Determine whether VCX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of VCX3B is measured. Determine whether VCX3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":156
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":126
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of S100A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of S100A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1917
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in CEBPD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in CEBPD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6065
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2055
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor POC1B-GALNT4 expression. Decide whether this perturbation leads to a significant alteration in POC1B-GALNT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor POC1B-GALNT4 expression. Decide whether this perturbation leads to a significant alteration in POC1B-GALNT4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1978
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ZNF677 expression is quantified. Does this perturbation result in a significant change in ZNF677 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and ZNF677 expression is quantified. Does this perturbation result in a significant change in ZNF677 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3092
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6230
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-646I6.6. Does perturbing SLC4A1 lead to a significant change in RP11-646I6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-646I6.6. Does perturbing SLC4A1 lead to a significant change in RP11-646I6.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1071
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Determine whether LINC00479 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of LINC00479 is measured. Determine whether LINC00479 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":416
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and CCRL2 expression is measured. Determine whether CCRL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":349
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and SLC31A2 expression is observed. Does this perturbation lead to a significant difference in SLC31A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and SLC31A2 expression is observed. Does this perturbation lead to a significant difference in SLC31A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5413
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor PHGDH expression. Decide whether this perturbation leads to a significant alteration in PHGDH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4508
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and MAOB expression is measured. Determine whether MAOB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and MAOB expression is measured. Determine whether MAOB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1499
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of TAC3. Does this perturbation cause a significant change in TAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of TAC3. Does this perturbation cause a significant change in TAC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3804
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1479
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and MYB expression is quantified. Does this perturbation result in a significant change in MYB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and MYB expression is quantified. Does this perturbation result in a significant change in MYB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2102
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3004
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Does this perturbation cause a significant change in RHOXF2BB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Does this perturbation cause a significant change in RHOXF2BB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5710
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5459
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5027
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ARHGDIB. Does perturbing SGK1 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of ARHGDIB. Does perturbing SGK1 lead to a significant change in ARHGDIB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4021
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3550
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3736
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD9 expression is quantified. Does this perturbation result in a significant change in CD9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3742
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in RP11-505P4.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in RP11-505P4.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1135
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in AC139099.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in AC139099.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3475
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of LINC01338. Does perturbing OSR2 lead to a significant change in LINC01338 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of LINC01338. Does perturbing OSR2 lead to a significant change in LINC01338 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5071
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of CHST15. Does this perturbation cause a significant change in CHST15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of CHST15. Does this perturbation cause a significant change in CHST15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2494
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PPFIA4 expression is measured. Determine whether PPFIA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PPFIA4 expression is measured. Determine whether PPFIA4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5309
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4277
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Does this perturbation cause a significant change in CKS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CKS2 is measured. Does this perturbation cause a significant change in CKS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2070
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and KIAA2012 expression is observed. Does this perturbation lead to a significant difference in KIAA2012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and KIAA2012 expression is observed. Does this perturbation lead to a significant difference in KIAA2012 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":113
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of GRN. Does this perturbation cause a significant change in GRN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5884
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of AC020571.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of AC020571.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1217
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TUBA1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TUBA1A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2715
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2988
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1416
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Does this perturbation cause a significant change in SLCO6A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of SLCO6A1 is measured. Does this perturbation cause a significant change in SLCO6A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4350
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and AC144568.2 expression is quantified. Does this perturbation result in a significant change in AC144568.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and AC144568.2 expression is quantified. Does this perturbation result in a significant change in AC144568.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":592
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Determine whether MYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Determine whether MYB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2106
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Determine whether ESAM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5276
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor VASH1 expression. Decide whether this perturbation leads to a significant alteration in VASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor VASH1 expression. Decide whether this perturbation leads to a significant alteration in VASH1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3358
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor ARHGDIB expression. Decide whether this perturbation leads to a significant alteration in ARHGDIB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4028
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Does this perturbation cause a significant change in FLJ12825 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Does this perturbation cause a significant change in FLJ12825 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":170
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of AC078941.1. Does this perturbation cause a significant change in AC078941.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of AC078941.1. Does this perturbation cause a significant change in AC078941.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2014
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of LRRC36. Does this perturbation cause a significant change in LRRC36 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of LRRC36. Does this perturbation cause a significant change in LRRC36 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":334
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3784
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of XK. Does perturbing PTPN12 lead to a significant change in XK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of XK. Does perturbing PTPN12 lead to a significant change in XK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2621
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of MCC. Does perturbing FOXF1 lead to a significant change in MCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of MCC. Does perturbing FOXF1 lead to a significant change in MCC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3511
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and AC064834.2 expression is measured. Determine whether AC064834.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and AC064834.2 expression is measured. Determine whether AC064834.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2449
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of VMP1. Does this perturbation cause a significant change in VMP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of VMP1. Does this perturbation cause a significant change in VMP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5864
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2940
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SPANXN5. Does perturbing COL1A1 lead to a significant change in SPANXN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SPANXN5. Does perturbing COL1A1 lead to a significant change in SPANXN5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3461
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD9 expression is observed. Does this perturbation lead to a significant difference in CD9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3743
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is quantified. Does this perturbation result in a significant change in CTD-2311M21.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CTD-2311M21.3 expression is quantified. Does this perturbation result in a significant change in CTD-2311M21.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":402
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Determine whether RP11-52L5.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Determine whether RP11-52L5.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6206
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP11-445O3.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445O3.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RP11-445O3.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-445O3.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":48
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of TTC9B. Does perturbing ISL2 lead to a significant change in TTC9B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of TTC9B. Does perturbing ISL2 lead to a significant change in TTC9B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4491
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and INADL expression is observed. Does this perturbation lead to a significant difference in INADL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and INADL expression is observed. Does this perturbation lead to a significant difference in INADL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2253
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of RP4-565E6.1. Does perturbing ELMSAN1 lead to a significant change in RP4-565E6.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of RP4-565E6.1. Does perturbing ELMSAN1 lead to a significant change in RP4-565E6.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":291
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and PERM1 expression is measured. Determine whether PERM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and PERM1 expression is measured. Determine whether PERM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5489
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in AK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in AK8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4395
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of CD24 is measured. Determine whether CD24 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3576
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1383
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTC-492K19.4 expression is observed. Does this perturbation lead to a significant difference in CTC-492K19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and CTC-492K19.4 expression is observed. Does this perturbation lead to a significant difference in CTC-492K19.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1123
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and CRYAB expression is quantified. Does this perturbation result in a significant change in CRYAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and CRYAB expression is quantified. Does this perturbation result in a significant change in CRYAB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1342
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and PHACTR1 expression is measured. Determine whether PHACTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and PHACTR1 expression is measured. Determine whether PHACTR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4389
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in KIAA2012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in KIAA2012 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":115
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3432
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ZNF610 expression. Decide whether this perturbation leads to a significant alteration in ZNF610 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor ZNF610 expression. Decide whether this perturbation leads to a significant alteration in ZNF610 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2438
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor DNAJB1 expression. Decide whether this perturbation leads to a significant alteration in DNAJB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor DNAJB1 expression. Decide whether this perturbation leads to a significant alteration in DNAJB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3868
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Determine whether SOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Determine whether SOX5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2476
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and FILIP1L expression is observed. Does this perturbation lead to a significant difference in FILIP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K3 is perturbed and FILIP1L expression is observed. Does this perturbation lead to a significant difference in FILIP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2263
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and RIMBP3C expression is quantified. Does this perturbation result in a significant change in RIMBP3C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and RIMBP3C expression is quantified. Does this perturbation result in a significant change in RIMBP3C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3282
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of TSC22D4. Does perturbing DUSP9 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of TSC22D4. Does perturbing DUSP9 lead to a significant change in TSC22D4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":191
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and FBXL20 expression is measured. Determine whether FBXL20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5769
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of IGDCC3. Does this perturbation cause a significant change in IGDCC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2324
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4954
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1728
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of DYNLL1. Does perturbing FOSB lead to a significant change in DYNLL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of DYNLL1. Does perturbing FOSB lead to a significant change in DYNLL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2811
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4047
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ANTXR2 expression is observed. Does this perturbation lead to a significant difference in ANTXR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and ANTXR2 expression is observed. Does this perturbation lead to a significant difference in ANTXR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5583
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of COLGALT2. Does perturbing FOXL2 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of COLGALT2. Does perturbing FOXL2 lead to a significant change in COLGALT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4091
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LINC01562 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in LINC01562 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1315
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and GPR157 expression is measured. Determine whether GPR157 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and GPR157 expression is measured. Determine whether GPR157 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3059
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Determine whether CHP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of CHP1 is measured. Determine whether CHP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5466
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of LEFTY1. Does perturbing HOXA13 lead to a significant change in LEFTY1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of LEFTY1. Does perturbing HOXA13 lead to a significant change in LEFTY1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5911
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ETS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in ETS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":585
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3614
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Does this perturbation cause a significant change in MFGE8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2480
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of AK8. Does perturbing IGDCC3 lead to a significant change in AK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of AK8. Does perturbing IGDCC3 lead to a significant change in AK8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4391
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and COTL1 expression is quantified. Does this perturbation result in a significant change in COTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and COTL1 expression is quantified. Does this perturbation result in a significant change in COTL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1282
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of LINC01342. Does perturbing CELF2 lead to a significant change in LINC01342 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of LINC01342. Does perturbing CELF2 lead to a significant change in LINC01342 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2201
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3195
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1646
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of TTC9B. Does this perturbation cause a significant change in TTC9B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of TTC9B. Does this perturbation cause a significant change in TTC9B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4494
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIST1H2AC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3187
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3846
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Determine whether RP11-259K5.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Determine whether RP11-259K5.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1246
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CPXM1 expression. Decide whether this perturbation leads to a significant alteration in CPXM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CPXM1 expression. Decide whether this perturbation leads to a significant alteration in CPXM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":388
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CREB3L2. Does this perturbation cause a significant change in CREB3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of CREB3L2. Does this perturbation cause a significant change in CREB3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5994
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4970
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ZNF677 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in ZNF677 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3095
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RP3-467K16.2. Does this perturbation cause a significant change in RP3-467K16.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1474
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor AC020571.3 expression. Decide whether this perturbation leads to a significant alteration in AC020571.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor AC020571.3 expression. Decide whether this perturbation leads to a significant alteration in AC020571.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1218
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in FAM49A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in FAM49A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":475
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Determine whether CBL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of CBL is measured. Determine whether CBL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3146
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SLC20A1 expression. Decide whether this perturbation leads to a significant alteration in SLC20A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SLC20A1 expression. Decide whether this perturbation leads to a significant alteration in SLC20A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2408
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and SH3RF2 expression is observed. Does this perturbation lead to a significant difference in SH3RF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and SH3RF2 expression is observed. Does this perturbation lead to a significant difference in SH3RF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3233
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Determine whether RP11-1085N6.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of RP11-1085N6.3 is measured. Determine whether RP11-1085N6.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3406
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CENPE expression is observed. Does this perturbation lead to a significant difference in CENPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CENPE expression is observed. Does this perturbation lead to a significant difference in CENPE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6223
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of RP11-355B11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of RP11-355B11.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1177
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5515
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor TM6SF2 expression. Decide whether this perturbation leads to a significant alteration in TM6SF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4378
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in HIST1H2AC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3185
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":435
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and RNF182 expression is quantified. Does this perturbation result in a significant change in RNF182 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and RNF182 expression is quantified. Does this perturbation result in a significant change in RNF182 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3952
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor TOX expression. Decide whether this perturbation leads to a significant alteration in TOX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor TOX expression. Decide whether this perturbation leads to a significant alteration in TOX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1368
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in IL1RN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in IL1RN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2195
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and HBD expression is quantified. Does this perturbation result in a significant change in HBD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5102
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PTRF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PTRF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1037
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is quantified. Does this perturbation result in a significant change in RP11-195B3.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and RP11-195B3.1 expression is quantified. Does this perturbation result in a significant change in RP11-195B3.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2212
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of S100A13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1827
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and PCDHGA3 expression is quantified. Does this perturbation result in a significant change in PCDHGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and PCDHGA3 expression is quantified. Does this perturbation result in a significant change in PCDHGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2562
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of CST9L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of CST9L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3337
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor TNFRSF12A expression. Decide whether this perturbation leads to a significant alteration in TNFRSF12A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor TNFRSF12A expression. Decide whether this perturbation leads to a significant alteration in TNFRSF12A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3908
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and TNNI3 expression is observed. Does this perturbation lead to a significant difference in TNNI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2703
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-505P4.7. Does perturbing IER5L lead to a significant change in RP11-505P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of RP11-505P4.7. Does perturbing IER5L lead to a significant change in RP11-505P4.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2551
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Determine whether CST9L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Determine whether CST9L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3336
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and RASGRF2 expression is quantified. Does this perturbation result in a significant change in RASGRF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and RASGRF2 expression is quantified. Does this perturbation result in a significant change in RASGRF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1542
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5268
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and AC144568.2 expression is measured. Determine whether AC144568.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and AC144568.2 expression is measured. Determine whether AC144568.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":599
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Determine whether IGDCC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2326
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of AC064834.2. Does this perturbation cause a significant change in AC064834.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of AC064834.2. Does this perturbation cause a significant change in AC064834.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2444
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is measured. Determine whether RPL17-C18orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and RPL17-C18orf32 expression is measured. Determine whether RPL17-C18orf32 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5779
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4965
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and PTPRS expression is observed. Does this perturbation lead to a significant difference in PTPRS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and PTPRS expression is observed. Does this perturbation lead to a significant difference in PTPRS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":663
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of TNFAIP8. Does perturbing CELF2 lead to a significant change in TNFAIP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of TNFAIP8. Does perturbing CELF2 lead to a significant change in TNFAIP8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2181
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ADGRF1 expression is observed. Does this perturbation lead to a significant difference in ADGRF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and ADGRF1 expression is observed. Does this perturbation lead to a significant difference in ADGRF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5723
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in PAQR7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1185
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ADGB expression is observed. Does this perturbation lead to a significant difference in ADGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and ADGB expression is observed. Does this perturbation lead to a significant difference in ADGB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5543
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Does this perturbation cause a significant change in ZNF85 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Does this perturbation cause a significant change in ZNF85 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":510
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4478
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of CLU. Does perturbing TSC22D1 lead to a significant change in CLU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of CLU. Does perturbing TSC22D1 lead to a significant change in CLU expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":11
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CITED2 expression is observed. Does this perturbation lead to a significant difference in CITED2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CITED2 expression is observed. Does this perturbation lead to a significant difference in CITED2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4283
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Does this perturbation cause a significant change in C1orf228 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of C1orf228 is measured. Does this perturbation cause a significant change in C1orf228 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Determine whether TOX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Determine whether TOX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1366
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ARRDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in ARRDC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":235
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and FOXL2 expression is measured. Determine whether FOXL2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3689
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4323
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of TUBB. Does perturbing TP73 lead to a significant change in TUBB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of TUBB. Does perturbing TP73 lead to a significant change in TUBB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2641
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and SLCO6A1 expression is observed. Does this perturbation lead to a significant difference in SLCO6A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and SLCO6A1 expression is observed. Does this perturbation lead to a significant difference in SLCO6A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4353
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ST3GAL5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of ST3GAL5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1767
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CITED2 expression is measured. Determine whether CITED2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and CITED2 expression is measured. Determine whether CITED2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4289
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PLK4, does the expression profile of ZFP36L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3677
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of FEZ1. Does this perturbation cause a significant change in FEZ1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3564
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of CCNG2. Does this perturbation cause a significant change in CCNG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of CCNG2. Does this perturbation cause a significant change in CCNG2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4064
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of VCX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of VCX3B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":157
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3718
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of CTSW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of CTSW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5367
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5703
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of FAM19A2. Does perturbing SAMD1 lead to a significant change in FAM19A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of FAM19A2. Does perturbing SAMD1 lead to a significant change in FAM19A2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3361
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of PXK. Does this perturbation cause a significant change in PXK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of PXK. Does this perturbation cause a significant change in PXK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2174
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CCNL1 expression is measured. Determine whether CCNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and CCNL1 expression is measured. Determine whether CCNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6149
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3486
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":809
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and DDX58 expression is quantified. Does this perturbation result in a significant change in DDX58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and DDX58 expression is quantified. Does this perturbation result in a significant change in DDX58 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":222
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and FMNL1 expression is observed. Does this perturbation lead to a significant difference in FMNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and FMNL1 expression is observed. Does this perturbation lead to a significant difference in FMNL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1693
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":66
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and FAM49A expression is quantified. Does this perturbation result in a significant change in FAM49A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and FAM49A expression is quantified. Does this perturbation result in a significant change in FAM49A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":472
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and TDRD12 expression is observed. Does this perturbation lead to a significant difference in TDRD12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and TDRD12 expression is observed. Does this perturbation lead to a significant difference in TDRD12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":93
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor LTC4S expression. Decide whether this perturbation leads to a significant alteration in LTC4S expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor LTC4S expression. Decide whether this perturbation leads to a significant alteration in LTC4S expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3648
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3504
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SLC2A3. Does this perturbation cause a significant change in SLC2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of SLC2A3. Does this perturbation cause a significant change in SLC2A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2534
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1145
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-505P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-505P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2558
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of C1orf228. Does this perturbation cause a significant change in C1orf228 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of C1orf228. Does this perturbation cause a significant change in C1orf228 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1114
  }
]