,question,answer,question_new 2673,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and DYNLT3 expression is observed. Does this perturbation lead to a significant difference in DYNLT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and DYNLT3 expression is observed. Does this perturbation lead to a significant difference in DYNLT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is quantified. Does this perturbation result in a significant change in RP4-550H1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is quantified. Does this perturbation result in a significant change in RP4-550H1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4093,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of TRGVA. Does perturbing TBX3 lead to a significant change in TRGVA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of TRGVA. Does perturbing TBX3 lead to a significant change in TRGVA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of CSRNP1. Does perturbing CSRNP1 lead to a significant change in CSRNP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of CSRNP1. Does perturbing CSRNP1 lead to a significant change in CSRNP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ATP8A1. Does this perturbation cause a significant change in ATP8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ATP8A1. Does this perturbation cause a significant change in ATP8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in SPTAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in SPTAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 70,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in IGFL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in IGFL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4678,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 723,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5468,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CHP1 expression. Decide whether this perturbation leads to a significant alteration in CHP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CHP1 expression. Decide whether this perturbation leads to a significant alteration in CHP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6183,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3830,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Does this perturbation cause a significant change in RP3-510H16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Does this perturbation cause a significant change in RP3-510H16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AC034228.4 expression is quantified. Does this perturbation result in a significant change in AC034228.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AC034228.4 expression is quantified. Does this perturbation result in a significant change in AC034228.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Determine whether CMB9-22P13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Determine whether CMB9-22P13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of BMP2K. Does perturbing MIDN lead to a significant change in BMP2K expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of BMP2K. Does perturbing MIDN lead to a significant change in BMP2K expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Determine whether RP1-59D14.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Determine whether RP1-59D14.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 888,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CTD-2031P19.5 expression. Decide whether this perturbation leads to a significant alteration in CTD-2031P19.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CTD-2031P19.5 expression. Decide whether this perturbation leads to a significant alteration in CTD-2031P19.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2528,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Determine whether CCNB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Determine whether CCNB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2948,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1140,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in MYO1F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in MYO1F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5363,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and CTSW expression is observed. Does this perturbation lead to a significant difference in CTSW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and CTSW expression is observed. Does this perturbation lead to a significant difference in CTSW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of TACC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of TACC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in CTB-49A3.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in CTB-49A3.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4624,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in DYNLL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in DYNLL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of LINC00479 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of LINC00479 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1170,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Does this perturbation cause a significant change in RP11-355B11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Does this perturbation cause a significant change in RP11-355B11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in APOBR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in APOBR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in PCDHGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in PCDHGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3160,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ATP9A. Does perturbing GLB1L2 lead to a significant change in ATP9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ATP9A. Does perturbing GLB1L2 lead to a significant change in ATP9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLEKHO1 expression is measured. Determine whether PLEKHO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLEKHO1 expression is measured. Determine whether PLEKHO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-510J16.5. Does perturbing SLC4A1 lead to a significant change in RP11-510J16.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-510J16.5. Does perturbing SLC4A1 lead to a significant change in RP11-510J16.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3438,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CTD-2012K14.6. Does perturbing CEBPB lead to a significant change in CTD-2012K14.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CTD-2012K14.6. Does perturbing CEBPB lead to a significant change in CTD-2012K14.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and STRC expression is measured. Determine whether STRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and STRC expression is measured. Determine whether STRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of FLJ12825 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of FLJ12825 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PHLDA2. Does perturbing CNNM4 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PHLDA2. Does perturbing CNNM4 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-52L5.6. Does perturbing EGR1 lead to a significant change in RP11-52L5.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-52L5.6. Does perturbing EGR1 lead to a significant change in RP11-52L5.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4268,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1780,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Does this perturbation cause a significant change in RP11-567N4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Does this perturbation cause a significant change in RP11-567N4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Determine whether RP11-635N19.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Determine whether RP11-635N19.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ATF6B. Does this perturbation cause a significant change in ATF6B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ATF6B. Does this perturbation cause a significant change in ATF6B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3068,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2048,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2540,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3720,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Does this perturbation cause a significant change in FABP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Does this perturbation cause a significant change in FABP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 82,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01420. Does this perturbation cause a significant change in LINC01420 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01420. Does this perturbation cause a significant change in LINC01420 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is measured. Determine whether RP5-1142A6.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is measured. Determine whether RP5-1142A6.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Determine whether AC007246.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Determine whether AC007246.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RPL17-C18orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RPL17-C18orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in STRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in STRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-328J14.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-328J14.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3963,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in TLCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in TLCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ARRDC3. Does this perturbation cause a significant change in ARRDC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ARRDC3. Does this perturbation cause a significant change in ARRDC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3688,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of TUBB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of TUBB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and CRABP2 expression is quantified. Does this perturbation result in a significant change in CRABP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and CRABP2 expression is quantified. Does this perturbation result in a significant change in CRABP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of FAM225B. Does this perturbation cause a significant change in FAM225B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of FAM225B. Does this perturbation cause a significant change in FAM225B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3713,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of CPVL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of CPVL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ZNF431. Does perturbing SNAI1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ZNF431. Does perturbing SNAI1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FAM83A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FAM83A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LRRTM4 expression is quantified. Does this perturbation result in a significant change in LRRTM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LRRTM4 expression is quantified. Does this perturbation result in a significant change in LRRTM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CCDC159 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CCDC159 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and SERPINF1 expression is measured. Determine whether SERPINF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and SERPINF1 expression is measured. Determine whether SERPINF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in LMNA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in LMNA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HCN1 expression is quantified. Does this perturbation result in a significant change in HCN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HCN1 expression is quantified. Does this perturbation result in a significant change in HCN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is quantified. Does this perturbation result in a significant change in RP11-1085N6.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is quantified. Does this perturbation result in a significant change in RP11-1085N6.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 893,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and TAS2R9 expression is observed. Does this perturbation lead to a significant difference in TAS2R9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and TAS2R9 expression is observed. Does this perturbation lead to a significant difference in TAS2R9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and DYNLL1 expression is quantified. Does this perturbation result in a significant change in DYNLL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and DYNLL1 expression is quantified. Does this perturbation result in a significant change in DYNLL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 608,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor RP11-445F12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-445F12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor RP11-445F12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-445F12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3343,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and RP11-76E17.2 expression is observed. Does this perturbation lead to a significant difference in RP11-76E17.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and RP11-76E17.2 expression is observed. Does this perturbation lead to a significant difference in RP11-76E17.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3088,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4428,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor COL21A1 expression. Decide whether this perturbation leads to a significant alteration in COL21A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor COL21A1 expression. Decide whether this perturbation leads to a significant alteration in COL21A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of MYO1F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of MYO1F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and LINC01003 expression is measured. Determine whether LINC01003 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and LINC01003 expression is measured. Determine whether LINC01003 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Determine whether TRIM31 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Determine whether TRIM31 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Determine whether APOL6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Determine whether APOL6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5988,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3273,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CARMN expression is observed. Does this perturbation lead to a significant difference in CARMN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CARMN expression is observed. Does this perturbation lead to a significant difference in CARMN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5883,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3583,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and IGHEP2 expression is observed. Does this perturbation lead to a significant difference in IGHEP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and IGHEP2 expression is observed. Does this perturbation lead to a significant difference in IGHEP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in RP11-369K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in RP11-369K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5330,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Does this perturbation cause a significant change in HIST1H3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Does this perturbation cause a significant change in HIST1H3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3708,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-290K4.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290K4.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-290K4.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290K4.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5918,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor LEFTY1 expression. Decide whether this perturbation leads to a significant alteration in LEFTY1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor LEFTY1 expression. Decide whether this perturbation leads to a significant alteration in LEFTY1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CPXM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CPXM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ADGB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ADGB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA5 expression is measured. Determine whether ANXA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA5 expression is measured. Determine whether ANXA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of VGF. Does this perturbation cause a significant change in VGF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of VGF. Does this perturbation cause a significant change in VGF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and CCNB2 expression is measured. Determine whether CCNB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and CCNB2 expression is measured. Determine whether CCNB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of CCDC136. Does this perturbation cause a significant change in CCDC136 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of CCDC136. Does this perturbation cause a significant change in CCDC136 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ZIC4. Does this perturbation cause a significant change in ZIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ZIC4. Does this perturbation cause a significant change in ZIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of LINC01003 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of LINC01003 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2783,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4290,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Does this perturbation cause a significant change in AC034228.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Does this perturbation cause a significant change in AC034228.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 45,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP11-445O3.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP11-445O3.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6073,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and RP11-38J22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-38J22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and RP11-38J22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-38J22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 910,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of KCNH2. Does this perturbation cause a significant change in KCNH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of KCNH2. Does this perturbation cause a significant change in KCNH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and DNAJB1 expression is measured. Determine whether DNAJB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and DNAJB1 expression is measured. Determine whether DNAJB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Does this perturbation cause a significant change in TRAPPC3L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Does this perturbation cause a significant change in TRAPPC3L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 253,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in HCAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in HCAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1048,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor S100A4 expression. Decide whether this perturbation leads to a significant alteration in S100A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor S100A4 expression. Decide whether this perturbation leads to a significant alteration in S100A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LRP10. Does perturbing FOXA3 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LRP10. Does perturbing FOXA3 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is measured. Determine whether XX-FW83563B9.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is measured. Determine whether XX-FW83563B9.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5088,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ASIC4 expression is measured. Determine whether ASIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ASIC4 expression is measured. Determine whether ASIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01395. Does this perturbation cause a significant change in LINC01395 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01395. Does this perturbation cause a significant change in LINC01395 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and MOGAT2 expression is quantified. Does this perturbation result in a significant change in MOGAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and MOGAT2 expression is quantified. Does this perturbation result in a significant change in MOGAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of LST1. Does perturbing KLF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of LST1. Does perturbing KLF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 993,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and AC007193.6 expression is quantified. Does this perturbation result in a significant change in AC007193.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and AC007193.6 expression is quantified. Does this perturbation result in a significant change in AC007193.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4048,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2300,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Determine whether SLC2A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Determine whether SLC2A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1770,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Does this perturbation cause a significant change in RP11-219B4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Does this perturbation cause a significant change in RP11-219B4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CTD-3126B10.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CTD-3126B10.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ZNF85. Does perturbing GLB1L2 lead to a significant change in ZNF85 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ZNF85. Does perturbing GLB1L2 lead to a significant change in ZNF85 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4540,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5708,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and TNFAIP2 expression is quantified. Does this perturbation result in a significant change in TNFAIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and TNFAIP2 expression is quantified. Does this perturbation result in a significant change in TNFAIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5073,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and LINC01338 expression is observed. Does this perturbation lead to a significant difference in LINC01338 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and LINC01338 expression is observed. Does this perturbation lead to a significant difference in LINC01338 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3100,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Does this perturbation cause a significant change in LPAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Does this perturbation cause a significant change in LPAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CD37 expression is quantified. Does this perturbation result in a significant change in CD37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CD37 expression is quantified. Does this perturbation result in a significant change in CD37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2150,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Does this perturbation cause a significant change in NUDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Does this perturbation cause a significant change in NUDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PSMB9 expression is measured. Determine whether PSMB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PSMB9 expression is measured. Determine whether PSMB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2298,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AC007246.3 expression. Decide whether this perturbation leads to a significant alteration in AC007246.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AC007246.3 expression. Decide whether this perturbation leads to a significant alteration in AC007246.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and CEBPD expression is measured. Determine whether CEBPD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and CEBPD expression is measured. Determine whether CEBPD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SNCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SNCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of WBP2. Does perturbing STIL lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of WBP2. Does perturbing STIL lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6120,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Does this perturbation cause a significant change in PLEKHO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Does this perturbation cause a significant change in PLEKHO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of HMOX1. Does this perturbation cause a significant change in HMOX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of HMOX1. Does this perturbation cause a significant change in HMOX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5748,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ALAS2. Does perturbing CDKN1C lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ALAS2. Does perturbing CDKN1C lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Determine whether ZNF610 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Determine whether ZNF610 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Does this perturbation cause a significant change in CCDC159 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Does this perturbation cause a significant change in CCDC159 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in LTC4S expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in LTC4S expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1700,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Does this perturbation cause a significant change in SP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Does this perturbation cause a significant change in SP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Determine whether SLC22A25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Determine whether SLC22A25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ADD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ADD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2838,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA2 expression. Decide whether this perturbation leads to a significant alteration in ANXA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA2 expression. Decide whether this perturbation leads to a significant alteration in ANXA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CDK1 expression is quantified. Does this perturbation result in a significant change in CDK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CDK1 expression is quantified. Does this perturbation result in a significant change in CDK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5373,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ACTC1 expression is observed. Does this perturbation lead to a significant difference in ACTC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ACTC1 expression is observed. Does this perturbation lead to a significant difference in ACTC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of TAS2R9. Does perturbing SET lead to a significant change in TAS2R9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of TAS2R9. Does perturbing SET lead to a significant change in TAS2R9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LRP10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LRP10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4643,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and CSRNP1 expression is observed. Does this perturbation lead to a significant difference in CSRNP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and CSRNP1 expression is observed. Does this perturbation lead to a significant difference in CSRNP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of FADS1. Does perturbing SLC6A9 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of FADS1. Does perturbing SLC6A9 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 72,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ATG2A expression is measured. Determine whether ATG2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ATG2A expression is measured. Determine whether ATG2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Determine whether MBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Determine whether MBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of RIMBP3C. Does perturbing CLDN6 lead to a significant change in RIMBP3C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of RIMBP3C. Does perturbing CLDN6 lead to a significant change in RIMBP3C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1684,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of LMNA. Does this perturbation cause a significant change in LMNA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of LMNA. Does this perturbation cause a significant change in LMNA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AC034228.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AC034228.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3565,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CYP3A5. Does this perturbation cause a significant change in CYP3A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CYP3A5. Does this perturbation cause a significant change in CYP3A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SLC2A1-AS1. Does perturbing S1PR2 lead to a significant change in SLC2A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SLC2A1-AS1. Does perturbing S1PR2 lead to a significant change in SLC2A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ALAS2. Does perturbing FOXF1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ALAS2. Does perturbing FOXF1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Determine whether PSMB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Determine whether PSMB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CD46. Does perturbing CEBPA lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CD46. Does perturbing CEBPA lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of HSD17B4. Does this perturbation cause a significant change in HSD17B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of HSD17B4. Does this perturbation cause a significant change in HSD17B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of INADL. Does perturbing MAP2K3 lead to a significant change in INADL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of INADL. Does perturbing MAP2K3 lead to a significant change in INADL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CKS2 expression is measured. Determine whether CKS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CKS2 expression is measured. Determine whether CKS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ASIC4 expression is quantified. Does this perturbation result in a significant change in ASIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ASIC4 expression is quantified. Does this perturbation result in a significant change in ASIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is measured. Determine whether RP11-369K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is measured. Determine whether RP11-369K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6168,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor DLX4 expression. Decide whether this perturbation leads to a significant alteration in DLX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor DLX4 expression. Decide whether this perturbation leads to a significant alteration in DLX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CCS. Does perturbing CEBPE lead to a significant change in CCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CCS. Does perturbing CEBPE lead to a significant change in CCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and TFAP2A expression is quantified. Does this perturbation result in a significant change in TFAP2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and TFAP2A expression is quantified. Does this perturbation result in a significant change in TFAP2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Determine whether ADGB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Determine whether ADGB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1463,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CYP3A5 expression is quantified. Does this perturbation result in a significant change in CYP3A5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CYP3A5 expression is quantified. Does this perturbation result in a significant change in CYP3A5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5943,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of AC006262.5. Does perturbing GLB1L2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of AC006262.5. Does perturbing GLB1L2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CCNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CCNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AC034228.4. Does this perturbation cause a significant change in AC034228.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AC034228.4. Does this perturbation cause a significant change in AC034228.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2990,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Does this perturbation cause a significant change in FZD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Does this perturbation cause a significant change in FZD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1670,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Does this perturbation cause a significant change in DEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Does this perturbation cause a significant change in DEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TPM4 expression is quantified. Does this perturbation result in a significant change in TPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TPM4 expression is quantified. Does this perturbation result in a significant change in TPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3484,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and SLC38A2 expression is measured. Determine whether SLC38A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and SLC38A2 expression is measured. Determine whether SLC38A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of MTURN. Does this perturbation cause a significant change in MTURN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of MTURN. Does this perturbation cause a significant change in MTURN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Determine whether HMOX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Determine whether HMOX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3938,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MS4A2 expression. Decide whether this perturbation leads to a significant alteration in MS4A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MS4A2 expression. Decide whether this perturbation leads to a significant alteration in MS4A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3641,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of LTC4S. Does perturbing PRTG lead to a significant change in LTC4S expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of LTC4S. Does perturbing PRTG lead to a significant change in LTC4S expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 909,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Does this perturbation cause a significant change in N4BP2L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Does this perturbation cause a significant change in N4BP2L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and SOX5 expression is measured. Determine whether SOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and SOX5 expression is measured. Determine whether SOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of CALY. Does this perturbation cause a significant change in CALY expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of CALY. Does this perturbation cause a significant change in CALY expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in GPR35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in GPR35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in PCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in PCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Determine whether HIST1H3H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Determine whether HIST1H3H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 700,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Does this perturbation cause a significant change in TAS1R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Does this perturbation cause a significant change in TAS1R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTC-492K19.4. Does this perturbation cause a significant change in CTC-492K19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTC-492K19.4. Does this perturbation cause a significant change in CTC-492K19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2333,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and C1orf141 expression is observed. Does this perturbation lead to a significant difference in C1orf141 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and C1orf141 expression is observed. Does this perturbation lead to a significant difference in C1orf141 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-1017G21.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-1017G21.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 130,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Does this perturbation cause a significant change in CCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Does this perturbation cause a significant change in CCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of FAM49A. Does this perturbation cause a significant change in FAM49A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of FAM49A. Does this perturbation cause a significant change in FAM49A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LRRTM4 expression is measured. Determine whether LRRTM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LRRTM4 expression is measured. Determine whether LRRTM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ABCA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ABCA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RP11-285F7.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RP11-285F7.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CCNB1. Does perturbing C3orf72 lead to a significant change in CCNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CCNB1. Does perturbing C3orf72 lead to a significant change in CCNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2568,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor PCDHGA3 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor PCDHGA3 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ABCA13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ABCA13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of GPR35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of GPR35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2918,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor H1FNT expression. Decide whether this perturbation leads to a significant alteration in H1FNT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor H1FNT expression. Decide whether this perturbation leads to a significant alteration in H1FNT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1778,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-219B4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-219B4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-219B4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-219B4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PTRF expression is measured. Determine whether PTRF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PTRF expression is measured. Determine whether PTRF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 773,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RNF168 expression is observed. Does this perturbation lead to a significant difference in RNF168 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RNF168 expression is observed. Does this perturbation lead to a significant difference in RNF168 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Determine whether ARPC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Determine whether ARPC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of TAC3. Does perturbing ARRDC3 lead to a significant change in TAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of TAC3. Does perturbing ARRDC3 lead to a significant change in TAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1483,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of LINC01342. Does this perturbation cause a significant change in LINC01342 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of LINC01342. Does this perturbation cause a significant change in LINC01342 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1423,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and TRPM2 expression is observed. Does this perturbation lead to a significant difference in TRPM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and TRPM2 expression is observed. Does this perturbation lead to a significant difference in TRPM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4240,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Does this perturbation cause a significant change in SEMA3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Does this perturbation cause a significant change in SEMA3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5123,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and CCNJL expression is observed. Does this perturbation lead to a significant difference in CCNJL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and CCNJL expression is observed. Does this perturbation lead to a significant difference in CCNJL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4100,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Determine whether ST3GAL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Determine whether ST3GAL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Determine whether MYO1F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Determine whether MYO1F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SLC2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SLC2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 363,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and MT1E expression is observed. Does this perturbation lead to a significant difference in MT1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and MT1E expression is observed. Does this perturbation lead to a significant difference in MT1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLAUR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLAUR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2073,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CKS2 expression is observed. Does this perturbation lead to a significant difference in CKS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CKS2 expression is observed. Does this perturbation lead to a significant difference in CKS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 418,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor LINC00479 expression. Decide whether this perturbation leads to a significant alteration in LINC00479 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor LINC00479 expression. Decide whether this perturbation leads to a significant alteration in LINC00479 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2218,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor RP11-195B3.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195B3.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor RP11-195B3.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195B3.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of TRAPPC3L. Does this perturbation cause a significant change in TRAPPC3L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of TRAPPC3L. Does this perturbation cause a significant change in TRAPPC3L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLA2G1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLA2G1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4313,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CYP1B1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP1B1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CYP1B1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP1B1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in LEFTY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in LEFTY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Determine whether KCNH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Determine whether KCNH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of SLCO6A1. Does this perturbation cause a significant change in SLCO6A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of SLCO6A1. Does this perturbation cause a significant change in SLCO6A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-345P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-345P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4883,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in LRRC36 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in LRRC36 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5990,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Does this perturbation cause a significant change in CREB3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Does this perturbation cause a significant change in CREB3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4273,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2143,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCM2L expression is observed. Does this perturbation lead to a significant difference in CCM2L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCM2L expression is observed. Does this perturbation lead to a significant difference in CCM2L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of MSRB1. Does perturbing TP73 lead to a significant change in MSRB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of MSRB1. Does perturbing TP73 lead to a significant change in MSRB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of TACC1. Does this perturbation cause a significant change in TACC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of TACC1. Does this perturbation cause a significant change in TACC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of TLN1. Does perturbing MIDN lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of TLN1. Does perturbing MIDN lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1270,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of NUMB. Does this perturbation cause a significant change in NUMB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of NUMB. Does this perturbation cause a significant change in NUMB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TUBA1A expression is quantified. Does this perturbation result in a significant change in TUBA1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TUBA1A expression is quantified. Does this perturbation result in a significant change in TUBA1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 928,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5110,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 9,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 16,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Determine whether CLU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Determine whether CLU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in CAPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in CAPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1908,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor RP1-261G23.7 expression. Decide whether this perturbation leads to a significant alteration in RP1-261G23.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor RP1-261G23.7 expression. Decide whether this perturbation leads to a significant alteration in RP1-261G23.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of UCKL1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of UCKL1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of FNDC3A. Does this perturbation cause a significant change in FNDC3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of FNDC3A. Does this perturbation cause a significant change in FNDC3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5458,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and SEMA3B expression is measured. Determine whether SEMA3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and SEMA3B expression is measured. Determine whether SEMA3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3815,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-563J2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-563J2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3460,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Does this perturbation cause a significant change in SPANXN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Does this perturbation cause a significant change in SPANXN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of TEX30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of TEX30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ARPC3 expression is quantified. Does this perturbation result in a significant change in ARPC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ARPC3 expression is quantified. Does this perturbation result in a significant change in ARPC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in SEMA3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in SEMA3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ACTB expression is quantified. Does this perturbation result in a significant change in ACTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ACTB expression is quantified. Does this perturbation result in a significant change in ACTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in DEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in DEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1753,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and S100A1 expression is observed. Does this perturbation lead to a significant difference in S100A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and S100A1 expression is observed. Does this perturbation lead to a significant difference in S100A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and TNFAIP8 expression is quantified. Does this perturbation result in a significant change in TNFAIP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and TNFAIP8 expression is quantified. Does this perturbation result in a significant change in TNFAIP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3820,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 743,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Determine whether RPL17-C18orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Determine whether RPL17-C18orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of SLCO6A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of SLCO6A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2938,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ARL6IP1 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ARL6IP1 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2490,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Does this perturbation cause a significant change in CHST15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Does this perturbation cause a significant change in CHST15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in TTC9B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in TTC9B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6000,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Does this perturbation cause a significant change in TACC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Does this perturbation cause a significant change in TACC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and AC078941.1 expression is quantified. Does this perturbation result in a significant change in AC078941.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and AC078941.1 expression is quantified. Does this perturbation result in a significant change in AC078941.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4520,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is measured. Determine whether CTD-3131K8.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is measured. Determine whether CTD-3131K8.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6153,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLA2G16 expression is observed. Does this perturbation lead to a significant difference in PLA2G16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLA2G16 expression is observed. Does this perturbation lead to a significant difference in PLA2G16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5160,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ARRDC3 expression is measured. Determine whether ARRDC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ARRDC3 expression is measured. Determine whether ARRDC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of RP11-195B3.1. Does this perturbation cause a significant change in RP11-195B3.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of RP11-195B3.1. Does this perturbation cause a significant change in RP11-195B3.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of MYLIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of MYLIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1313,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LINC01562 expression is observed. Does this perturbation lead to a significant difference in LINC01562 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LINC01562 expression is observed. Does this perturbation lead to a significant difference in LINC01562 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ATP10D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ATP10D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of CRABP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of CRABP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of RP11-662J14.2. Does this perturbation cause a significant change in RP11-662J14.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of RP11-662J14.2. Does this perturbation cause a significant change in RP11-662J14.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3618,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4670,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Determine whether PLEKHO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Determine whether PLEKHO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of CPVL. Does perturbing BCL2L11 lead to a significant change in CPVL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of CPVL. Does perturbing BCL2L11 lead to a significant change in CPVL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is quantified. Does this perturbation result in a significant change in CTD-3037G24.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is quantified. Does this perturbation result in a significant change in CTD-3037G24.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4286,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Determine whether CITED2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Determine whether CITED2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ABCB11 expression is quantified. Does this perturbation result in a significant change in ABCB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ABCB11 expression is quantified. Does this perturbation result in a significant change in ABCB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP1-34B20.21. Does perturbing TSC22D1 lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP1-34B20.21. Does perturbing TSC22D1 lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of CLTA. Does perturbing MAP2K6 lead to a significant change in CLTA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of CLTA. Does perturbing MAP2K6 lead to a significant change in CLTA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 120,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and MKNK2 expression is measured. Determine whether MKNK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and MKNK2 expression is measured. Determine whether MKNK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Determine whether CRYAB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Determine whether CRYAB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CDK1. Does this perturbation cause a significant change in CDK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CDK1. Does this perturbation cause a significant change in CDK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SLC2A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SLC2A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Determine whether RP11-505P4.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Determine whether RP11-505P4.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 963,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3838,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP3-510H16.3 expression. Decide whether this perturbation leads to a significant alteration in RP3-510H16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP3-510H16.3 expression. Decide whether this perturbation leads to a significant alteration in RP3-510H16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6090,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1838,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SLC22A25 expression. Decide whether this perturbation leads to a significant alteration in SLC22A25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SLC22A25 expression. Decide whether this perturbation leads to a significant alteration in SLC22A25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4446,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Determine whether RHOH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Determine whether RHOH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of SLC4A3. Does perturbing HK2 lead to a significant change in SLC4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of SLC4A3. Does perturbing HK2 lead to a significant change in SLC4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is measured. Determine whether TMEM35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is measured. Determine whether TMEM35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3568,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Determine whether LTC4S shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Determine whether LTC4S shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5230,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Does this perturbation cause a significant change in FAM225B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Does this perturbation cause a significant change in FAM225B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MS4A3. Does this perturbation cause a significant change in MS4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MS4A3. Does this perturbation cause a significant change in MS4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and BCL2L11 expression is measured. Determine whether BCL2L11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and BCL2L11 expression is measured. Determine whether BCL2L11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in RP11-290L1.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in RP11-290L1.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 678,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5180,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Does this perturbation cause a significant change in TMEM88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Does this perturbation cause a significant change in TMEM88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 148,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor HSD17B4 expression. Decide whether this perturbation leads to a significant alteration in HSD17B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor HSD17B4 expression. Decide whether this perturbation leads to a significant alteration in HSD17B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is quantified. Does this perturbation result in a significant change in CACNA1C-AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is quantified. Does this perturbation result in a significant change in CACNA1C-AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of PRKAG2-AS1. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of PRKAG2-AS1. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 708,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor TAS1R1 expression. Decide whether this perturbation leads to a significant alteration in TAS1R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor TAS1R1 expression. Decide whether this perturbation leads to a significant alteration in TAS1R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3330,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Does this perturbation cause a significant change in CST9L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Does this perturbation cause a significant change in CST9L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Determine whether EWSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Determine whether EWSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of HMGA2. Does perturbing C3orf72 lead to a significant change in HMGA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of HMGA2. Does perturbing C3orf72 lead to a significant change in HMGA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6248,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and IL1RN expression is quantified. Does this perturbation result in a significant change in IL1RN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and IL1RN expression is quantified. Does this perturbation result in a significant change in IL1RN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CD37 expression is measured. Determine whether CD37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CD37 expression is measured. Determine whether CD37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is measured. Determine whether RP11-662J14.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is measured. Determine whether RP11-662J14.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and COL1A1 expression is measured. Determine whether COL1A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and COL1A1 expression is measured. Determine whether COL1A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 400,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1268,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of HBG1. Does this perturbation cause a significant change in HBG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of HBG1. Does this perturbation cause a significant change in HBG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2790,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Does this perturbation cause a significant change in KRT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Does this perturbation cause a significant change in KRT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Determine whether RP11-714G18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Determine whether RP11-714G18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP3-510H16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP3-510H16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4784,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of RP11-202A13.1. Does this perturbation cause a significant change in RP11-202A13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of RP11-202A13.1. Does this perturbation cause a significant change in RP11-202A13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Determine whether PLEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Determine whether PLEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and AC078941.1 expression is measured. Determine whether AC078941.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and AC078941.1 expression is measured. Determine whether AC078941.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of EWSAT1. Does this perturbation cause a significant change in EWSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of EWSAT1. Does this perturbation cause a significant change in EWSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4310,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3143,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and CBL expression is observed. Does this perturbation lead to a significant difference in CBL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and CBL expression is observed. Does this perturbation lead to a significant difference in CBL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and LINC01003 expression is quantified. Does this perturbation result in a significant change in LINC01003 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and LINC01003 expression is quantified. Does this perturbation result in a significant change in LINC01003 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3323,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2217,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of RP11-195B3.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of RP11-195B3.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4713,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RP5-1142A6.2 expression is observed. Does this perturbation lead to a significant difference in RP5-1142A6.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RP5-1142A6.2 expression is observed. Does this perturbation lead to a significant difference in RP5-1142A6.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3628,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of TUBB3. Does perturbing ZBTB1 lead to a significant change in TUBB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of TUBB3. Does perturbing ZBTB1 lead to a significant change in TUBB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of RBM5-AS1. Does perturbing CEBPE lead to a significant change in RBM5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of RBM5-AS1. Does perturbing CEBPE lead to a significant change in RBM5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4832,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and NCALD expression is quantified. Does this perturbation result in a significant change in NCALD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and NCALD expression is quantified. Does this perturbation result in a significant change in NCALD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and PCK1 expression is measured. Determine whether PCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and PCK1 expression is measured. Determine whether PCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is measured. Determine whether RP11-52L5.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is measured. Determine whether RP11-52L5.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1598,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor CALY expression. Decide whether this perturbation leads to a significant alteration in CALY expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor CALY expression. Decide whether this perturbation leads to a significant alteration in CALY expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in AC078941.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in AC078941.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CYP2C18. Does perturbing TBX3 lead to a significant change in CYP2C18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CYP2C18. Does perturbing TBX3 lead to a significant change in CYP2C18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1520,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3898,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor HMGA2 expression. Decide whether this perturbation leads to a significant alteration in HMGA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor HMGA2 expression. Decide whether this perturbation leads to a significant alteration in HMGA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 873,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6058,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4000,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Does this perturbation cause a significant change in SLC22A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Does this perturbation cause a significant change in SLC22A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and TRGVA expression is quantified. Does this perturbation result in a significant change in TRGVA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and TRGVA expression is quantified. Does this perturbation result in a significant change in TRGVA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AC007246.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AC007246.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of SP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of SP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5738,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor PCK1 expression. Decide whether this perturbation leads to a significant alteration in PCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor PCK1 expression. Decide whether this perturbation leads to a significant alteration in PCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5853,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and SCG5 expression is observed. Does this perturbation lead to a significant difference in SCG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and SCG5 expression is observed. Does this perturbation lead to a significant difference in SCG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ATP8A1. Does perturbing FOXF1 lead to a significant change in ATP8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ATP8A1. Does perturbing FOXF1 lead to a significant change in ATP8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5488,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor PERM1 expression. Decide whether this perturbation leads to a significant alteration in PERM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor PERM1 expression. Decide whether this perturbation leads to a significant alteration in PERM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and TAS2R9 expression is quantified. Does this perturbation result in a significant change in TAS2R9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and TAS2R9 expression is quantified. Does this perturbation result in a significant change in TAS2R9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of AC144568.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of AC144568.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1438,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTD-3037G24.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3037G24.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTD-3037G24.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3037G24.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in VMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in VMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1650,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CCDC159. Does this perturbation cause a significant change in CCDC159 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CCDC159. Does this perturbation cause a significant change in CCDC159 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of RP11-355B11.2. Does perturbing ZNF318 lead to a significant change in RP11-355B11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of RP11-355B11.2. Does perturbing ZNF318 lead to a significant change in RP11-355B11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3950,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Does this perturbation cause a significant change in RNF182 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Does this perturbation cause a significant change in RNF182 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ID1. Does perturbing NCL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ID1. Does perturbing NCL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in PXK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in PXK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2170,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Does this perturbation cause a significant change in PXK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Does this perturbation cause a significant change in PXK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of SLCO6A1. Does perturbing KMT2A lead to a significant change in SLCO6A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of SLCO6A1. Does perturbing KMT2A lead to a significant change in SLCO6A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4393,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and AK8 expression is observed. Does this perturbation lead to a significant difference in AK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and AK8 expression is observed. Does this perturbation lead to a significant difference in AK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and CRYAB expression is measured. Determine whether CRYAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and CRYAB expression is measured. Determine whether CRYAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in IL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in IL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of TPH2. Does this perturbation cause a significant change in TPH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of TPH2. Does this perturbation cause a significant change in TPH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in EWSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in EWSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1916,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Determine whether S100A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Determine whether S100A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of C10orf11. Does perturbing ZC3HAV1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of C10orf11. Does perturbing ZC3HAV1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 337,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of LRRC36 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of LRRC36 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of DRC1. Does perturbing PTPN13 lead to a significant change in DRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of DRC1. Does perturbing PTPN13 lead to a significant change in DRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and IGHEP2 expression is quantified. Does this perturbation result in a significant change in IGHEP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and IGHEP2 expression is quantified. Does this perturbation result in a significant change in IGHEP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and APOBR expression is measured. Determine whether APOBR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and APOBR expression is measured. Determine whether APOBR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of KRT79 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of KRT79 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5220,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Does this perturbation cause a significant change in CIB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Does this perturbation cause a significant change in CIB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of HEATR9. Does perturbing CDKN1A lead to a significant change in HEATR9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of HEATR9. Does perturbing CDKN1A lead to a significant change in HEATR9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2452,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and RETN expression is quantified. Does this perturbation result in a significant change in RETN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and RETN expression is quantified. Does this perturbation result in a significant change in RETN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2100,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Does this perturbation cause a significant change in MYB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Does this perturbation cause a significant change in MYB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5998,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CREB3L2 expression. Decide whether this perturbation leads to a significant alteration in CREB3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CREB3L2 expression. Decide whether this perturbation leads to a significant alteration in CREB3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of CCR10. Does perturbing RHOXF2BB lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of CCR10. Does perturbing RHOXF2BB lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and RNF182 expression is measured. Determine whether RNF182 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and RNF182 expression is measured. Determine whether RNF182 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1548,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor RASGRF2 expression. Decide whether this perturbation leads to a significant alteration in RASGRF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor RASGRF2 expression. Decide whether this perturbation leads to a significant alteration in RASGRF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1713,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4723,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and WDR88 expression is observed. Does this perturbation lead to a significant difference in WDR88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and WDR88 expression is observed. Does this perturbation lead to a significant difference in WDR88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 638,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor COL18A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in COL18A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor COL18A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in COL18A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RUNX3. Does this perturbation cause a significant change in RUNX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RUNX3. Does this perturbation cause a significant change in RUNX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5012,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is quantified. Does this perturbation result in a significant change in TMEM35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is quantified. Does this perturbation result in a significant change in TMEM35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of PLEK. Does perturbing SPI1 lead to a significant change in PLEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of PLEK. Does perturbing SPI1 lead to a significant change in PLEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 320,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 515,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ZNF85 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ZNF85 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4023,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1690,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Does this perturbation cause a significant change in FMNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Does this perturbation cause a significant change in FMNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and S100A3 expression is quantified. Does this perturbation result in a significant change in S100A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and S100A3 expression is quantified. Does this perturbation result in a significant change in S100A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of DNAJB1. Does perturbing C3orf72 lead to a significant change in DNAJB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of DNAJB1. Does perturbing C3orf72 lead to a significant change in DNAJB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5930,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Does this perturbation cause a significant change in LBH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Does this perturbation cause a significant change in LBH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1000,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Does this perturbation cause a significant change in MBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Does this perturbation cause a significant change in MBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and SH3RF2 expression is quantified. Does this perturbation result in a significant change in SH3RF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and SH3RF2 expression is quantified. Does this perturbation result in a significant change in SH3RF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4550,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Does this perturbation cause a significant change in SLC8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Does this perturbation cause a significant change in SLC8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5393,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CMB9-22P13.1 expression is observed. Does this perturbation lead to a significant difference in CMB9-22P13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CMB9-22P13.1 expression is observed. Does this perturbation lead to a significant difference in CMB9-22P13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Determine whether SKAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Determine whether SKAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of HMOX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of HMOX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1590,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Does this perturbation cause a significant change in CALY expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Does this perturbation cause a significant change in CALY expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of MSRB1. Does this perturbation cause a significant change in MSRB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of MSRB1. Does this perturbation cause a significant change in MSRB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is quantified. Does this perturbation result in a significant change in RP11-635N19.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is quantified. Does this perturbation result in a significant change in RP11-635N19.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FAM83A expression is measured. Determine whether FAM83A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FAM83A expression is measured. Determine whether FAM83A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2768,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor IER3 expression. Decide whether this perturbation leads to a significant alteration in IER3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor IER3 expression. Decide whether this perturbation leads to a significant alteration in IER3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ADD3. Does this perturbation cause a significant change in ADD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ADD3. Does this perturbation cause a significant change in ADD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MYOZ3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MYOZ3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5208,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor TNFAIP2 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor TNFAIP2 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4660,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Does this perturbation cause a significant change in RP11-442O1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Does this perturbation cause a significant change in RP11-442O1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in CCNG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in CCNG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of SCG5. Does perturbing SNAI1 lead to a significant change in SCG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of SCG5. Does perturbing SNAI1 lead to a significant change in SCG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and AC020571.3 expression is quantified. Does this perturbation result in a significant change in AC020571.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and AC020571.3 expression is quantified. Does this perturbation result in a significant change in AC020571.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of MYL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of MYL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 653,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and STRA6 expression is observed. Does this perturbation lead to a significant difference in STRA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and STRA6 expression is observed. Does this perturbation lead to a significant difference in STRA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ICAM4 expression is measured. Determine whether ICAM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ICAM4 expression is measured. Determine whether ICAM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3588,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor IGHEP2 expression. Decide whether this perturbation leads to a significant alteration in IGHEP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor IGHEP2 expression. Decide whether this perturbation leads to a significant alteration in IGHEP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of WDR88. Does perturbing ARID1A lead to a significant change in WDR88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of WDR88. Does perturbing ARID1A lead to a significant change in WDR88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-1017G21.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-1017G21.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RP5-1142A6.2. Does perturbing ARID1A lead to a significant change in RP5-1142A6.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RP5-1142A6.2. Does perturbing ARID1A lead to a significant change in RP5-1142A6.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 625,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Determine whether C19orf38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Determine whether C19orf38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1743,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and MSX1 expression is quantified. Does this perturbation result in a significant change in MSX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and MSX1 expression is quantified. Does this perturbation result in a significant change in MSX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 430,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TMEM55A expression is measured. Determine whether TMEM55A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TMEM55A expression is measured. Determine whether TMEM55A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Determine whether FAM118A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Determine whether FAM118A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5568,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor MYL4 expression. Decide whether this perturbation leads to a significant alteration in MYL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor MYL4 expression. Decide whether this perturbation leads to a significant alteration in MYL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ATP9A. Does this perturbation cause a significant change in ATP9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ATP9A. Does this perturbation cause a significant change in ATP9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2428,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SDSL expression. Decide whether this perturbation leads to a significant alteration in SDSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SDSL expression. Decide whether this perturbation leads to a significant alteration in SDSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and SLC7A11 expression is quantified. Does this perturbation result in a significant change in SLC7A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and SLC7A11 expression is quantified. Does this perturbation result in a significant change in SLC7A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 33,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and PDE1B expression is observed. Does this perturbation lead to a significant difference in PDE1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and PDE1B expression is observed. Does this perturbation lead to a significant difference in PDE1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Determine whether CCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Determine whether CCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5223,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CIB3 expression is observed. Does this perturbation lead to a significant difference in CIB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CIB3 expression is observed. Does this perturbation lead to a significant difference in CIB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1537,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of SLC43A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of SLC43A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4096,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4730,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Does this perturbation cause a significant change in MACF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Does this perturbation cause a significant change in MACF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5420,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Does this perturbation cause a significant change in LINC01420 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Does this perturbation cause a significant change in LINC01420 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of CTSW. Does perturbing NIT1 lead to a significant change in CTSW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of CTSW. Does perturbing NIT1 lead to a significant change in CTSW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Determine whether DNAJB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Determine whether DNAJB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1998,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SLC2A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in SLC2A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SLC2A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in SLC2A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1518,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor MYO1F expression. Decide whether this perturbation leads to a significant alteration in MYO1F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor MYO1F expression. Decide whether this perturbation leads to a significant alteration in MYO1F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ALAS2. Does perturbing ARRDC3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ALAS2. Does perturbing ARRDC3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and TAC3 expression is quantified. Does this perturbation result in a significant change in TAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and TAC3 expression is quantified. Does this perturbation result in a significant change in TAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in RP11-180M15.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in RP11-180M15.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and KIAA2012 expression is quantified. Does this perturbation result in a significant change in KIAA2012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and KIAA2012 expression is quantified. Does this perturbation result in a significant change in KIAA2012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5780,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Does this perturbation cause a significant change in INHBE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Does this perturbation cause a significant change in INHBE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and MME expression is measured. Determine whether MME exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and MME expression is measured. Determine whether MME exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CHP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CHP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6158,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLA2G16 expression. Decide whether this perturbation leads to a significant alteration in PLA2G16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLA2G16 expression. Decide whether this perturbation leads to a significant alteration in PLA2G16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6080,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Does this perturbation cause a significant change in SLC4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Does this perturbation cause a significant change in SLC4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 263,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and VGF expression is observed. Does this perturbation lead to a significant difference in VGF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and VGF expression is observed. Does this perturbation lead to a significant difference in VGF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1758,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor S100A1 expression. Decide whether this perturbation leads to a significant alteration in S100A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor S100A1 expression. Decide whether this perturbation leads to a significant alteration in S100A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Determine whether CYP3A5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Determine whether CYP3A5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1553,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ATP8B4 expression is observed. Does this perturbation lead to a significant difference in ATP8B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ATP8B4 expression is observed. Does this perturbation lead to a significant difference in ATP8B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4943,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and LEFTY2 expression is observed. Does this perturbation lead to a significant difference in LEFTY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and LEFTY2 expression is observed. Does this perturbation lead to a significant difference in LEFTY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Determine whether SSTR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Determine whether SSTR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5925,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and CLTA expression is measured. Determine whether CLTA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and CLTA expression is measured. Determine whether CLTA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 983,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MS4A3 expression is observed. Does this perturbation lead to a significant difference in MS4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MS4A3 expression is observed. Does this perturbation lead to a significant difference in MS4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4628,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1630,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Does this perturbation cause a significant change in CEBPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Does this perturbation cause a significant change in CEBPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of RP1-34B20.21. Does perturbing KIF18B lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of RP1-34B20.21. Does perturbing KIF18B lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 14,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of CLU. Does this perturbation cause a significant change in CLU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of CLU. Does this perturbation cause a significant change in CLU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Determine whether RP11-83A24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Determine whether RP11-83A24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Determine whether RNF182 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Determine whether RNF182 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and N4BP2L2 expression is quantified. Does this perturbation result in a significant change in N4BP2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and N4BP2L2 expression is quantified. Does this perturbation result in a significant change in N4BP2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4474,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of MYC. Does perturbing IKZF3 lead to a significant change in MYC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of MYC. Does perturbing IKZF3 lead to a significant change in MYC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and PSMB8 expression is measured. Determine whether PSMB8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and PSMB8 expression is measured. Determine whether PSMB8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Determine whether SOCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Determine whether SOCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of CEBPA. Does this perturbation cause a significant change in CEBPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of CEBPA. Does this perturbation cause a significant change in CEBPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 843,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ARPC3 expression is observed. Does this perturbation lead to a significant difference in ARPC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ARPC3 expression is observed. Does this perturbation lead to a significant difference in ARPC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ZNF467. Does perturbing SET lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ZNF467. Does perturbing SET lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of IL1RN. Does this perturbation cause a significant change in IL1RN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of IL1RN. Does this perturbation cause a significant change in IL1RN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RUNX3. Does perturbing CITED1 lead to a significant change in RUNX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RUNX3. Does perturbing CITED1 lead to a significant change in RUNX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 533,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ATP9A expression is observed. Does this perturbation lead to a significant difference in ATP9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ATP9A expression is observed. Does this perturbation lead to a significant difference in ATP9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3758,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor TM4SF1-AS1 expression. Decide whether this perturbation leads to a significant alteration in TM4SF1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor TM4SF1-AS1 expression. Decide whether this perturbation leads to a significant alteration in TM4SF1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of TRAPPC3L. Does perturbing CDKN1C lead to a significant change in TRAPPC3L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of TRAPPC3L. Does perturbing CDKN1C lead to a significant change in TRAPPC3L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is quantified. Does this perturbation result in a significant change in RP11-286H15.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is quantified. Does this perturbation result in a significant change in RP11-286H15.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5050,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Does this perturbation cause a significant change in COL1A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Does this perturbation cause a significant change in COL1A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4620,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 590,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Does this perturbation cause a significant change in AC144568.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Does this perturbation cause a significant change in AC144568.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2083,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ACTB expression is observed. Does this perturbation lead to a significant difference in ACTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ACTB expression is observed. Does this perturbation lead to a significant difference in ACTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3965,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ANXA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ANXA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 540,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4843,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and C19orf38 expression is observed. Does this perturbation lead to a significant difference in C19orf38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and C19orf38 expression is observed. Does this perturbation lead to a significant difference in C19orf38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2630,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Does this perturbation cause a significant change in AC007193.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Does this perturbation cause a significant change in AC007193.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ZC3HAV1. Does perturbing ZC3HAV1 lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ZC3HAV1. Does perturbing ZC3HAV1 lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of RPS6KA2. Does perturbing DLX2 lead to a significant change in RPS6KA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of RPS6KA2. Does perturbing DLX2 lead to a significant change in RPS6KA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of TUBB3. Does this perturbation cause a significant change in TUBB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of TUBB3. Does this perturbation cause a significant change in TUBB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5521,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of SPARC. Does perturbing JUN lead to a significant change in SPARC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of SPARC. Does perturbing JUN lead to a significant change in SPARC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of TXNIP. Does perturbing ARID1A lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of TXNIP. Does perturbing ARID1A lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1303,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PCDHGA6 expression is observed. Does this perturbation lead to a significant difference in PCDHGA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PCDHGA6 expression is observed. Does this perturbation lead to a significant difference in PCDHGA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4709,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and CNN2 expression is measured. Determine whether CNN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and CNN2 expression is measured. Determine whether CNN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in SLC7A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in SLC7A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5241,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of RP11-662J14.2. Does perturbing CEBPB lead to a significant change in RP11-662J14.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of RP11-662J14.2. Does perturbing CEBPB lead to a significant change in RP11-662J14.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of BST2. Does perturbing IKZF3 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of BST2. Does perturbing IKZF3 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6228,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CENPE expression. Decide whether this perturbation leads to a significant alteration in CENPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CENPE expression. Decide whether this perturbation leads to a significant alteration in CENPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4830,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Does this perturbation cause a significant change in NCALD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Does this perturbation cause a significant change in NCALD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3223,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIPK1-AS1 expression is observed. Does this perturbation lead to a significant difference in HIPK1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIPK1-AS1 expression is observed. Does this perturbation lead to a significant difference in HIPK1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 288,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor CRABP2 expression. Decide whether this perturbation leads to a significant alteration in CRABP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor CRABP2 expression. Decide whether this perturbation leads to a significant alteration in CRABP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of CCNJL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of CCNJL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD24. Does perturbing BPGM lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD24. Does perturbing BPGM lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of MSX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of MSX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3363,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and FAM19A2 expression is observed. Does this perturbation lead to a significant difference in FAM19A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and FAM19A2 expression is observed. Does this perturbation lead to a significant difference in FAM19A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3098,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ZNF677 expression. Decide whether this perturbation leads to a significant alteration in ZNF677 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ZNF677 expression. Decide whether this perturbation leads to a significant alteration in ZNF677 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3383,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HHEX expression is observed. Does this perturbation lead to a significant difference in HHEX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HHEX expression is observed. Does this perturbation lead to a significant difference in HHEX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3780,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5860,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Does this perturbation cause a significant change in VMP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Does this perturbation cause a significant change in VMP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4608,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TMEM55A expression. Decide whether this perturbation leads to a significant alteration in TMEM55A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TMEM55A expression. Decide whether this perturbation leads to a significant alteration in TMEM55A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of LEFTY2. Does perturbing BCL2L11 lead to a significant change in LEFTY2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of LEFTY2. Does perturbing BCL2L11 lead to a significant change in LEFTY2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3078,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Determine whether RP11-219B4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Determine whether RP11-219B4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4388,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor PHACTR1 expression. Decide whether this perturbation leads to a significant alteration in PHACTR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor PHACTR1 expression. Decide whether this perturbation leads to a significant alteration in PHACTR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LST1. Does perturbing FOXA3 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LST1. Does perturbing FOXA3 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6109,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CPXM1. Does perturbing BCORL1 lead to a significant change in CPXM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CPXM1. Does perturbing BCORL1 lead to a significant change in CPXM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RNF168 expression is quantified. Does this perturbation result in a significant change in RNF168 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RNF168 expression is quantified. Does this perturbation result in a significant change in RNF168 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 553,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCDC148 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCDC148 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SOCS2. Does perturbing FEV lead to a significant change in SOCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SOCS2. Does perturbing FEV lead to a significant change in SOCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RGPD5 expression is quantified. Does this perturbation result in a significant change in RGPD5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RGPD5 expression is quantified. Does this perturbation result in a significant change in RGPD5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Determine whether ACTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Determine whether ACTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ABCB11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ABCB11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ATP8B4 expression is measured. Determine whether ATP8B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ATP8B4 expression is measured. Determine whether ATP8B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Determine whether S100A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Determine whether S100A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5880,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and MARCKS expression is measured. Determine whether MARCKS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and MARCKS expression is measured. Determine whether MARCKS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 780,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Does this perturbation cause a significant change in CD47 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Does this perturbation cause a significant change in CD47 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and NPW expression is quantified. Does this perturbation result in a significant change in NPW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and NPW expression is quantified. Does this perturbation result in a significant change in NPW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5493,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and IGFL2 expression is observed. Does this perturbation lead to a significant difference in IGFL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and IGFL2 expression is observed. Does this perturbation lead to a significant difference in IGFL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Determine whether UNC5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Determine whether UNC5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of HCAR2. Does perturbing STIL lead to a significant change in HCAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of HCAR2. Does perturbing STIL lead to a significant change in HCAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and INHBE expression is measured. Determine whether INHBE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and INHBE expression is measured. Determine whether INHBE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3063,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Determine whether ATP8B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Determine whether ATP8B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4763,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in VGF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in VGF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2060,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3790,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2868,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor HOGA1 expression. Decide whether this perturbation leads to a significant alteration in HOGA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor HOGA1 expression. Decide whether this perturbation leads to a significant alteration in HOGA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of HBE1. Does this perturbation cause a significant change in HBE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of HBE1. Does this perturbation cause a significant change in HBE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-219B4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-219B4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1863,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2089,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ACTB expression is measured. Determine whether ACTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ACTB expression is measured. Determine whether ACTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5808,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor DPYSL2 expression. Decide whether this perturbation leads to a significant alteration in DPYSL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor DPYSL2 expression. Decide whether this perturbation leads to a significant alteration in DPYSL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ACP5 expression is quantified. Does this perturbation result in a significant change in ACP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ACP5 expression is quantified. Does this perturbation result in a significant change in ACP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 698,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SOCS2 expression. Decide whether this perturbation leads to a significant alteration in SOCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SOCS2 expression. Decide whether this perturbation leads to a significant alteration in SOCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TRIM22. Does perturbing KIF2C lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TRIM22. Does perturbing KIF2C lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2848,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in SP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in SP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and DLX4 expression is quantified. Does this perturbation result in a significant change in DLX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and DLX4 expression is quantified. Does this perturbation result in a significant change in DLX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1130,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Does this perturbation cause a significant change in RP11-505P4.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Does this perturbation cause a significant change in RP11-505P4.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5369,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and CTSW expression is measured. Determine whether CTSW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and CTSW expression is measured. Determine whether CTSW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Determine whether PCDHGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Determine whether PCDHGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in RASGRF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in RASGRF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of FAM19A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of FAM19A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1033,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PTRF expression is observed. Does this perturbation lead to a significant difference in PTRF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PTRF expression is observed. Does this perturbation lead to a significant difference in PTRF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in COL1A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in COL1A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1760,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Does this perturbation cause a significant change in ST3GAL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Does this perturbation cause a significant change in ST3GAL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of SAT2. Does perturbing HOXB9 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of SAT2. Does perturbing HOXB9 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of DCAF13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of DCAF13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in CRYAB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in CRYAB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of RP11-286H15.1. Does perturbing TBX2 lead to a significant change in RP11-286H15.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of RP11-286H15.1. Does perturbing TBX2 lead to a significant change in RP11-286H15.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of SLC22A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of SLC22A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3600,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 233,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ARRDC3 expression is observed. Does this perturbation lead to a significant difference in ARRDC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ARRDC3 expression is observed. Does this perturbation lead to a significant difference in ARRDC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1198,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor CTD-2616J11.16 expression. Decide whether this perturbation leads to a significant alteration in CTD-2616J11.16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor CTD-2616J11.16 expression. Decide whether this perturbation leads to a significant alteration in CTD-2616J11.16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of PHACTR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of PHACTR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is measured. Determine whether TM4SF1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is measured. Determine whether TM4SF1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3268,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor NUMB expression. Decide whether this perturbation leads to a significant alteration in NUMB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor NUMB expression. Decide whether this perturbation leads to a significant alteration in NUMB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3403,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and RP11-1085N6.3 expression is observed. Does this perturbation lead to a significant difference in RP11-1085N6.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and RP11-1085N6.3 expression is observed. Does this perturbation lead to a significant difference in RP11-1085N6.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1188,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLEKHO1 expression is quantified. Does this perturbation result in a significant change in PLEKHO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLEKHO1 expression is quantified. Does this perturbation result in a significant change in PLEKHO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of FOXL2. Does perturbing PLK4 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of FOXL2. Does perturbing PLK4 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and PPP4R4 expression is measured. Determine whether PPP4R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and PPP4R4 expression is measured. Determine whether PPP4R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of PROX1. Does perturbing SGK1 lead to a significant change in PROX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of PROX1. Does perturbing SGK1 lead to a significant change in PROX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3508,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TPM4 expression is measured. Determine whether TPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TPM4 expression is measured. Determine whether TPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2520,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5915,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in LEFTY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in LEFTY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 238,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ARRDC3 expression. Decide whether this perturbation leads to a significant alteration in ARRDC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ARRDC3 expression. Decide whether this perturbation leads to a significant alteration in ARRDC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3528,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ATP8A1 expression. Decide whether this perturbation leads to a significant alteration in ATP8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ATP8A1 expression. Decide whether this perturbation leads to a significant alteration in ATP8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 84,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2042,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2723,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is quantified. Does this perturbation result in a significant change in CTC-490E21.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is quantified. Does this perturbation result in a significant change in CTC-490E21.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4170,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Does this perturbation cause a significant change in ABCA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Does this perturbation cause a significant change in ABCA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3372,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and DYNLL1 expression is measured. Determine whether DYNLL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and DYNLL1 expression is measured. Determine whether DYNLL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and KIAA2012 expression is measured. Determine whether KIAA2012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and KIAA2012 expression is measured. Determine whether KIAA2012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1943,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ORAI3 expression is observed. Does this perturbation lead to a significant difference in ORAI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ORAI3 expression is observed. Does this perturbation lead to a significant difference in ORAI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of CCNB2. Does this perturbation cause a significant change in CCNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of CCNB2. Does this perturbation cause a significant change in CCNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of TFAP2A. Does this perturbation cause a significant change in TFAP2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of TFAP2A. Does this perturbation cause a significant change in TFAP2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4600,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Does this perturbation cause a significant change in TMEM55A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Does this perturbation cause a significant change in TMEM55A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2510,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Does this perturbation cause a significant change in RP11-286H15.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Does this perturbation cause a significant change in RP11-286H15.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of SPARC. Does this perturbation cause a significant change in SPARC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of SPARC. Does this perturbation cause a significant change in SPARC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 480,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C6orf1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C6orf1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ARPC3. Does perturbing SET lead to a significant change in ARPC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ARPC3. Does perturbing SET lead to a significant change in ARPC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1773,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-219B4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-219B4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-219B4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-219B4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of RGS16. Does perturbing DUSP9 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of RGS16. Does perturbing DUSP9 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CTD-2311M21.3. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CTD-2311M21.3. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CTD-2311M21.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CTD-2311M21.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 30,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Does this perturbation cause a significant change in PDE1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Does this perturbation cause a significant change in PDE1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and GCM2 expression is quantified. Does this perturbation result in a significant change in GCM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and GCM2 expression is quantified. Does this perturbation result in a significant change in GCM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and RP11-91A18.4 expression is measured. Determine whether RP11-91A18.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and RP11-91A18.4 expression is measured. Determine whether RP11-91A18.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6133,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2260,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of S100A1. Does this perturbation cause a significant change in S100A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of S100A1. Does this perturbation cause a significant change in S100A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and TRAPPC3L expression is quantified. Does this perturbation result in a significant change in TRAPPC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and TRAPPC3L expression is quantified. Does this perturbation result in a significant change in TRAPPC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6274,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CTD-2378E12.1. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CTD-2378E12.1. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LRP10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LRP10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of RP11-369K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of RP11-369K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of MACF1. Does this perturbation cause a significant change in MACF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of MACF1. Does this perturbation cause a significant change in MACF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 808,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ARHGEF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ARHGEF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LINC01562. Does this perturbation cause a significant change in LINC01562 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LINC01562. Does this perturbation cause a significant change in LINC01562 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1228,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor TFRC expression. Decide whether this perturbation leads to a significant alteration in TFRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor TFRC expression. Decide whether this perturbation leads to a significant alteration in TFRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is quantified. Does this perturbation result in a significant change in RP11-202A13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is quantified. Does this perturbation result in a significant change in RP11-202A13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of TCAF2. Does perturbing IRF1 lead to a significant change in TCAF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of TCAF2. Does perturbing IRF1 lead to a significant change in TCAF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5260,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3103,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and LPAR2 expression is observed. Does this perturbation lead to a significant difference in LPAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and LPAR2 expression is observed. Does this perturbation lead to a significant difference in LPAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of NUDC. Does this perturbation cause a significant change in NUDC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of NUDC. Does this perturbation cause a significant change in NUDC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5650,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Does this perturbation cause a significant change in RELB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Does this perturbation cause a significant change in RELB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2180,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Does this perturbation cause a significant change in TNFAIP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Does this perturbation cause a significant change in TNFAIP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 183,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and LGALS12 expression is observed. Does this perturbation lead to a significant difference in LGALS12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and LGALS12 expression is observed. Does this perturbation lead to a significant difference in LGALS12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3978,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ARMCX3 expression. Decide whether this perturbation leads to a significant alteration in ARMCX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ARMCX3 expression. Decide whether this perturbation leads to a significant alteration in ARMCX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of LST1. Does perturbing ATL1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of LST1. Does perturbing ATL1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6010,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Does this perturbation cause a significant change in AMPH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Does this perturbation cause a significant change in AMPH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1554,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ATP8B4. Does this perturbation cause a significant change in ATP8B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ATP8B4. Does this perturbation cause a significant change in ATP8B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6050,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of SLC22A11. Does this perturbation cause a significant change in SLC22A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of SLC22A11. Does this perturbation cause a significant change in SLC22A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 396,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2040,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and TNFAIP2 expression is measured. Determine whether TNFAIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and TNFAIP2 expression is measured. Determine whether TNFAIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and SSTR3 expression is measured. Determine whether SSTR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and SSTR3 expression is measured. Determine whether SSTR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of PYROXD2. Does perturbing MAP2K3 lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of PYROXD2. Does perturbing MAP2K3 lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1023,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1348,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor CRYAB expression. Decide whether this perturbation leads to a significant alteration in CRYAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor CRYAB expression. Decide whether this perturbation leads to a significant alteration in CRYAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1880,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3823,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-1017G21.6 expression is observed. Does this perturbation lead to a significant difference in RP11-1017G21.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-1017G21.6 expression is observed. Does this perturbation lead to a significant difference in RP11-1017G21.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of SH3RF2. Does this perturbation cause a significant change in SH3RF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of SH3RF2. Does this perturbation cause a significant change in SH3RF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2933,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ARL6IP1 expression is observed. Does this perturbation lead to a significant difference in ARL6IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ARL6IP1 expression is observed. Does this perturbation lead to a significant difference in ARL6IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and FZD6 expression is measured. Determine whether FZD6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and FZD6 expression is measured. Determine whether FZD6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 463,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TRIM31 expression is observed. Does this perturbation lead to a significant difference in TRIM31 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TRIM31 expression is observed. Does this perturbation lead to a significant difference in TRIM31 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6078,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor RP11-38J22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-38J22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor RP11-38J22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-38J22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Determine whether ANXA5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Determine whether ANXA5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3340,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Does this perturbation cause a significant change in RP11-76E17.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Does this perturbation cause a significant change in RP11-76E17.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6098,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Determine whether WDR88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Determine whether WDR88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in PPP4R4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in PPP4R4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5238,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor FAM225B expression. Decide whether this perturbation leads to a significant alteration in FAM225B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor FAM225B expression. Decide whether this perturbation leads to a significant alteration in FAM225B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and PLEK expression is quantified. Does this perturbation result in a significant change in PLEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and PLEK expression is quantified. Does this perturbation result in a significant change in PLEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of MMP19. Does this perturbation cause a significant change in MMP19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of MMP19. Does this perturbation cause a significant change in MMP19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6278,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CTD-2378E12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2378E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CTD-2378E12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2378E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 730,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Does this perturbation cause a significant change in PLAUR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Does this perturbation cause a significant change in PLAUR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of HEMGN. Does perturbing LYL1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of HEMGN. Does perturbing LYL1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4198,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor SPANXD expression. Decide whether this perturbation leads to a significant alteration in SPANXD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor SPANXD expression. Decide whether this perturbation leads to a significant alteration in SPANXD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2900,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Does this perturbation cause a significant change in ADD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Does this perturbation cause a significant change in ADD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3726,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Determine whether FABP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Determine whether FABP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3943,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MYOZ3 expression is observed. Does this perturbation lead to a significant difference in MYOZ3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MYOZ3 expression is observed. Does this perturbation lead to a significant difference in MYOZ3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 538,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ATP9A expression. Decide whether this perturbation leads to a significant alteration in ATP9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ATP9A expression. Decide whether this perturbation leads to a significant alteration in ATP9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3300,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of PCDHGA3. Does this perturbation cause a significant change in PCDHGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of PCDHGA3. Does this perturbation cause a significant change in PCDHGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3760,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Does this perturbation cause a significant change in IL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Does this perturbation cause a significant change in IL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in RP11-968A15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in RP11-968A15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RPL17-C18orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RPL17-C18orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3640,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Does this perturbation cause a significant change in LTC4S expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Does this perturbation cause a significant change in LTC4S expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4340,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Does this perturbation cause a significant change in HIST1H4H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Does this perturbation cause a significant change in HIST1H4H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ACTC1. Does this perturbation cause a significant change in ACTC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ACTC1. Does this perturbation cause a significant change in ACTC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2270,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Does this perturbation cause a significant change in RP11-537H15.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Does this perturbation cause a significant change in RP11-537H15.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5408,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2468,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PCDHGA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PCDHGA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5790,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Does this perturbation cause a significant change in RP4-550H1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Does this perturbation cause a significant change in RP4-550H1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ATP8B4. Does perturbing MIDN lead to a significant change in ATP8B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ATP8B4. Does perturbing MIDN lead to a significant change in ATP8B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3368,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor FAM19A2 expression. Decide whether this perturbation leads to a significant alteration in FAM19A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor FAM19A2 expression. Decide whether this perturbation leads to a significant alteration in FAM19A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of FEZ1. Does perturbing CNNM4 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of FEZ1. Does perturbing CNNM4 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2878,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP11-345P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-345P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP11-345P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-345P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6163,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and DLX4 expression is observed. Does this perturbation lead to a significant difference in DLX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and DLX4 expression is observed. Does this perturbation lead to a significant difference in DLX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3190,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2283,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5986,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4010,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Does this perturbation cause a significant change in RP11-6D1.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Does this perturbation cause a significant change in RP11-6D1.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CDC45. Does perturbing CEBPE lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CDC45. Does perturbing CEBPE lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RP11-285F7.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RP11-285F7.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of KIAA2012. Does perturbing MAML2 lead to a significant change in KIAA2012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of KIAA2012. Does perturbing MAML2 lead to a significant change in KIAA2012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2553,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-505P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-505P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1018,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3338,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor CST9L expression. Decide whether this perturbation leads to a significant alteration in CST9L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor CST9L expression. Decide whether this perturbation leads to a significant alteration in CST9L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5670,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Does this perturbation cause a significant change in EGOT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Does this perturbation cause a significant change in EGOT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and SLC4A3 expression is quantified. Does this perturbation result in a significant change in SLC4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and SLC4A3 expression is quantified. Does this perturbation result in a significant change in SLC4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Determine whether RP3-510H16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Determine whether RP3-510H16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1298,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor DSC1 expression. Decide whether this perturbation leads to a significant alteration in DSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor DSC1 expression. Decide whether this perturbation leads to a significant alteration in DSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Determine whether SLC22A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Determine whether SLC22A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1828,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3814,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-563J2.3. Does this perturbation cause a significant change in RP11-563J2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-563J2.3. Does this perturbation cause a significant change in RP11-563J2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of FMNL1. Does this perturbation cause a significant change in FMNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of FMNL1. Does this perturbation cause a significant change in FMNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and TLCD2 expression is measured. Determine whether TLCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and TLCD2 expression is measured. Determine whether TLCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2483,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of DYNLT3. Does this perturbation cause a significant change in DYNLT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of DYNLT3. Does this perturbation cause a significant change in DYNLT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CARMN expression is measured. Determine whether CARMN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CARMN expression is measured. Determine whether CARMN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Determine whether RP11-537H15.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Determine whether RP11-537H15.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of SP6. Does this perturbation cause a significant change in SP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of SP6. Does this perturbation cause a significant change in SP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 478,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor FAM49A expression. Decide whether this perturbation leads to a significant alteration in FAM49A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor FAM49A expression. Decide whether this perturbation leads to a significant alteration in FAM49A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SLC22A25. Does this perturbation cause a significant change in SLC22A25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SLC22A25. Does this perturbation cause a significant change in SLC22A25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4993,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and MARCKS expression is observed. Does this perturbation lead to a significant difference in MARCKS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and MARCKS expression is observed. Does this perturbation lead to a significant difference in MARCKS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of RP11-968A15.2. Does this perturbation cause a significant change in RP11-968A15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of RP11-968A15.2. Does this perturbation cause a significant change in RP11-968A15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2323,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of MACF1. Does perturbing ARID1A lead to a significant change in MACF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of MACF1. Does perturbing ARID1A lead to a significant change in MACF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in MYC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in MYC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SOCS2 expression is quantified. Does this perturbation result in a significant change in SOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SOCS2 expression is quantified. Does this perturbation result in a significant change in SOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of FAM49A. Does perturbing MEIS1 lead to a significant change in FAM49A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of FAM49A. Does perturbing MEIS1 lead to a significant change in FAM49A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and TCAF2 expression is measured. Determine whether TCAF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and TCAF2 expression is measured. Determine whether TCAF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and AC004540.4 expression is quantified. Does this perturbation result in a significant change in AC004540.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and AC004540.4 expression is quantified. Does this perturbation result in a significant change in AC004540.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1328,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1073,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-646I6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-646I6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-646I6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-646I6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3948,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MYOZ3 expression. Decide whether this perturbation leads to a significant alteration in MYOZ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MYOZ3 expression. Decide whether this perturbation leads to a significant alteration in MYOZ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1020,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3073,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of NCKAP1L. Does perturbing CITED1 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of NCKAP1L. Does perturbing CITED1 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3468,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SPANXN5 expression. Decide whether this perturbation leads to a significant alteration in SPANXN5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SPANXN5 expression. Decide whether this perturbation leads to a significant alteration in SPANXN5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 948,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor MMP19 expression. Decide whether this perturbation leads to a significant alteration in MMP19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor MMP19 expression. Decide whether this perturbation leads to a significant alteration in MMP19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6150,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Does this perturbation cause a significant change in PLA2G16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Does this perturbation cause a significant change in PLA2G16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5866,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Determine whether VMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Determine whether VMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 300,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PAMR1 expression is quantified. Does this perturbation result in a significant change in PAMR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PAMR1 expression is quantified. Does this perturbation result in a significant change in PAMR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of CRYAB. Does this perturbation cause a significant change in CRYAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of CRYAB. Does this perturbation cause a significant change in CRYAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2631,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of AC007193.6. Does perturbing PTPN12 lead to a significant change in AC007193.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of AC007193.6. Does perturbing PTPN12 lead to a significant change in AC007193.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SOCS3. Does perturbing COL1A1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SOCS3. Does perturbing COL1A1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Determine whether BCL2L11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Determine whether BCL2L11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of RPS6KA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of RPS6KA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1860,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of DLX4. Does this perturbation cause a significant change in DLX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of DLX4. Does this perturbation cause a significant change in DLX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3608,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Determine whether LRRC36 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Determine whether LRRC36 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1052,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and AGXT expression is quantified. Does this perturbation result in a significant change in AGXT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and AGXT expression is quantified. Does this perturbation result in a significant change in AGXT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Determine whether GCM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Determine whether GCM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 133,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CCS expression is observed. Does this perturbation lead to a significant difference in CCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CCS expression is observed. Does this perturbation lead to a significant difference in CCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ARL6IP1. Does this perturbation cause a significant change in ARL6IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ARL6IP1. Does this perturbation cause a significant change in ARL6IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of NUDC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of NUDC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ANXA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ANXA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of NPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of NPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2308,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTSL. Does perturbing RREB1 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTSL. Does perturbing RREB1 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6260,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Does this perturbation cause a significant change in MME expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Does this perturbation cause a significant change in MME expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1143,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2740,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1211,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of AC020571.3. Does perturbing COL2A1 lead to a significant change in AC020571.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of AC020571.3. Does perturbing COL2A1 lead to a significant change in AC020571.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of RP4-565E6.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of RP4-565E6.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in SERPINF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in SERPINF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ANTXR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ANTXR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of AC139099.6. Does perturbing COL1A1 lead to a significant change in AC139099.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of AC139099.6. Does perturbing COL1A1 lead to a significant change in AC139099.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ZIC4 expression is quantified. Does this perturbation result in a significant change in ZIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ZIC4 expression is quantified. Does this perturbation result in a significant change in ZIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of FZD6. Does perturbing IRF1 lead to a significant change in FZD6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of FZD6. Does perturbing IRF1 lead to a significant change in FZD6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4270,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4697,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Determine whether CTD-3131K8.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Determine whether CTD-3131K8.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3800,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Does this perturbation cause a significant change in TAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Does this perturbation cause a significant change in TAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and TRPM2 expression is quantified. Does this perturbation result in a significant change in TRPM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and TRPM2 expression is quantified. Does this perturbation result in a significant change in TRPM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ZIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ZIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1203,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ACP5 expression is observed. Does this perturbation lead to a significant difference in ACP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ACP5 expression is observed. Does this perturbation lead to a significant difference in ACP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01358 expression is measured. Determine whether LINC01358 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01358 expression is measured. Determine whether LINC01358 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ICAM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ICAM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of PIM2. Does perturbing IRF1 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of PIM2. Does perturbing IRF1 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is quantified. Does this perturbation result in a significant change in RP11-442O1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is quantified. Does this perturbation result in a significant change in RP11-442O1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in TRAPPC3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in TRAPPC3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Determine whether AC144568.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Determine whether AC144568.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 298,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor RP4-565E6.1 expression. Decide whether this perturbation leads to a significant alteration in RP4-565E6.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor RP4-565E6.1 expression. Decide whether this perturbation leads to a significant alteration in RP4-565E6.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of KIAA2012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of KIAA2012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5288,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PSMB9 expression. Decide whether this perturbation leads to a significant alteration in PSMB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PSMB9 expression. Decide whether this perturbation leads to a significant alteration in PSMB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1053,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and AGXT expression is observed. Does this perturbation lead to a significant difference in AGXT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and AGXT expression is observed. Does this perturbation lead to a significant difference in AGXT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in NUDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in NUDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FADS1. Does perturbing FOXL2 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FADS1. Does perturbing FOXL2 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Determine whether PAMR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Determine whether PAMR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5791,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RP4-550H1.4. Does perturbing PTPN9 lead to a significant change in RP4-550H1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RP4-550H1.4. Does perturbing PTPN9 lead to a significant change in RP4-550H1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5370,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Does this perturbation cause a significant change in ACTC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Does this perturbation cause a significant change in ACTC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and HIST1H4H expression is quantified. Does this perturbation result in a significant change in HIST1H4H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and HIST1H4H expression is quantified. Does this perturbation result in a significant change in HIST1H4H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2383,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and HEATR9 expression is observed. Does this perturbation lead to a significant difference in HEATR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and HEATR9 expression is observed. Does this perturbation lead to a significant difference in HEATR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ACTC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ACTC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Does this perturbation cause a significant change in RP11-195B3.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Does this perturbation cause a significant change in RP11-195B3.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in AGXT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in AGXT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5768,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1510,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Does this perturbation cause a significant change in MYO1F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Does this perturbation cause a significant change in MYO1F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RP11-308D13.3. Does perturbing CBL lead to a significant change in RP11-308D13.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RP11-308D13.3. Does perturbing CBL lead to a significant change in RP11-308D13.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Determine whether LINC01342 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Determine whether LINC01342 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of RBM5-AS1. Does this perturbation cause a significant change in RBM5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of RBM5-AS1. Does this perturbation cause a significant change in RBM5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1240,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Does this perturbation cause a significant change in RP11-259K5.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Does this perturbation cause a significant change in RP11-259K5.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2030,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Does this perturbation cause a significant change in RP11-290L1.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Does this perturbation cause a significant change in RP11-290L1.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RNF168. Does perturbing CBL lead to a significant change in RNF168 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RNF168. Does perturbing CBL lead to a significant change in RNF168 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LINC01562 expression is measured. Determine whether LINC01562 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LINC01562 expression is measured. Determine whether LINC01562 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is quantified. Does this perturbation result in a significant change in RP11-1017G21.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is quantified. Does this perturbation result in a significant change in RP11-1017G21.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5307,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PPFIA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PPFIA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is measured. Determine whether CTD-3037G24.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is measured. Determine whether CTD-3037G24.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of HEMGN. Does perturbing DLX2 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of HEMGN. Does perturbing DLX2 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01358 expression is quantified. Does this perturbation result in a significant change in LINC01358 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01358 expression is quantified. Does this perturbation result in a significant change in LINC01358 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of GCM2. Does this perturbation cause a significant change in GCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of GCM2. Does this perturbation cause a significant change in GCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4488,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5830,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CHP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CHP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in LBH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in LBH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1563,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 54,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5520,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Does this perturbation cause a significant change in SPARC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Does this perturbation cause a significant change in SPARC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Determine whether HEATR9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Determine whether HEATR9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Determine whether SIGLEC15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Determine whether SIGLEC15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTB-161C1.1. Does perturbing UBASH3B lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTB-161C1.1. Does perturbing UBASH3B lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Determine whether TLCD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Determine whether TLCD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5293,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and KRTAP9-9 expression is observed. Does this perturbation lead to a significant difference in KRTAP9-9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and KRTAP9-9 expression is observed. Does this perturbation lead to a significant difference in KRTAP9-9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5270,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2205,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in LINC01342 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in LINC01342 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 118,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor KIAA2012 expression. Decide whether this perturbation leads to a significant alteration in KIAA2012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor KIAA2012 expression. Decide whether this perturbation leads to a significant alteration in KIAA2012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Determine whether RBM5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Determine whether RBM5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4813,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6193,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CRAT37 expression is observed. Does this perturbation lead to a significant difference in CRAT37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CRAT37 expression is observed. Does this perturbation lead to a significant difference in CRAT37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 389,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CPXM1 expression is measured. Determine whether CPXM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CPXM1 expression is measured. Determine whether CPXM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3650,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of SLC31A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of SLC31A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in DCAF13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in DCAF13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Determine whether TNFAIP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Determine whether TNFAIP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1608,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor RPS6KA2 expression. Decide whether this perturbation leads to a significant alteration in RPS6KA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor RPS6KA2 expression. Decide whether this perturbation leads to a significant alteration in RPS6KA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and HMOX1 expression is quantified. Does this perturbation result in a significant change in HMOX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and HMOX1 expression is quantified. Does this perturbation result in a significant change in HMOX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLA2G16. Does perturbing KIF18B lead to a significant change in PLA2G16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLA2G16. Does perturbing KIF18B lead to a significant change in PLA2G16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2840,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2846,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4333,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and CCNB2 expression is observed. Does this perturbation lead to a significant difference in CCNB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and CCNB2 expression is observed. Does this perturbation lead to a significant difference in CCNB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 15,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in CLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in CLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2110,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Does this perturbation cause a significant change in ARHGEF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Does this perturbation cause a significant change in ARHGEF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of RP11-290L1.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of RP11-290L1.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1302,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is quantified. Does this perturbation result in a significant change in PCDHGA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is quantified. Does this perturbation result in a significant change in PCDHGA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5378,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ACTC1 expression. Decide whether this perturbation leads to a significant alteration in ACTC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ACTC1 expression. Decide whether this perturbation leads to a significant alteration in ACTC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2133,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCDC148 expression is observed. Does this perturbation lead to a significant difference in CCDC148 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCDC148 expression is observed. Does this perturbation lead to a significant difference in CCDC148 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3913,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in STAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in STAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CD37. Does this perturbation cause a significant change in CD37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CD37. Does this perturbation cause a significant change in CD37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Determine whether SDSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Determine whether SDSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and STRA6 expression is measured. Determine whether STRA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and STRA6 expression is measured. Determine whether STRA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of RP11-195C7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of RP11-195C7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of LINC01342 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of LINC01342 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3683,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4783,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and RP11-202A13.1 expression is observed. Does this perturbation lead to a significant difference in RP11-202A13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and RP11-202A13.1 expression is observed. Does this perturbation lead to a significant difference in RP11-202A13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6060,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Does this perturbation cause a significant change in CEBPD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Does this perturbation cause a significant change in CEBPD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 39,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and PDE1B expression is measured. Determine whether PDE1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and PDE1B expression is measured. Determine whether PDE1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and RLN3 expression is measured. Determine whether RLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and RLN3 expression is measured. Determine whether RLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of XX-FW83563B9.5. Does perturbing CLDN6 lead to a significant change in XX-FW83563B9.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of XX-FW83563B9.5. Does perturbing CLDN6 lead to a significant change in XX-FW83563B9.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1410,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 923,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM118A. Does perturbing TP73 lead to a significant change in FAM118A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM118A. Does perturbing TP73 lead to a significant change in FAM118A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and AMPH expression is measured. Determine whether AMPH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and AMPH expression is measured. Determine whether AMPH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CDK1 expression is measured. Determine whether CDK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CDK1 expression is measured. Determine whether CDK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PSMB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PSMB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5540,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Does this perturbation cause a significant change in ADGB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Does this perturbation cause a significant change in ADGB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CST3. Does perturbing MAP7D1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CST3. Does perturbing MAP7D1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and PCK1 expression is quantified. Does this perturbation result in a significant change in PCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and PCK1 expression is quantified. Does this perturbation result in a significant change in PCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1088,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor SERPINF1 expression. Decide whether this perturbation leads to a significant alteration in SERPINF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor SERPINF1 expression. Decide whether this perturbation leads to a significant alteration in SERPINF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of SEMA3B. Does this perturbation cause a significant change in SEMA3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of SEMA3B. Does this perturbation cause a significant change in SEMA3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and MARCKS expression is quantified. Does this perturbation result in a significant change in MARCKS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and MARCKS expression is quantified. Does this perturbation result in a significant change in MARCKS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5728,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ADGRF1 expression. Decide whether this perturbation leads to a significant alteration in ADGRF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ADGRF1 expression. Decide whether this perturbation leads to a significant alteration in ADGRF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in PROX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in PROX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and DRC1 expression is quantified. Does this perturbation result in a significant change in DRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and DRC1 expression is quantified. Does this perturbation result in a significant change in DRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTC-492K19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTC-492K19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 490,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 823,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and AC007556.3 expression is observed. Does this perturbation lead to a significant difference in AC007556.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and AC007556.3 expression is observed. Does this perturbation lead to a significant difference in AC007556.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 913,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Determine whether PPP4R4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Determine whether PPP4R4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3864,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of DNAJB1. Does this perturbation cause a significant change in DNAJB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of DNAJB1. Does this perturbation cause a significant change in DNAJB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ATF6B. Does perturbing NIT1 lead to a significant change in ATF6B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ATF6B. Does perturbing NIT1 lead to a significant change in ATF6B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and AK8 expression is measured. Determine whether AK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and AK8 expression is measured. Determine whether AK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 702,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and TAS1R1 expression is quantified. Does this perturbation result in a significant change in TAS1R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and TAS1R1 expression is quantified. Does this perturbation result in a significant change in TAS1R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of TCAF2. Does this perturbation cause a significant change in TCAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of TCAF2. Does this perturbation cause a significant change in TCAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5630,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4410,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CYP3A5. Does perturbing SET lead to a significant change in CYP3A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CYP3A5. Does perturbing SET lead to a significant change in CYP3A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2460,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and GIPR expression is quantified. Does this perturbation result in a significant change in GIPR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and GIPR expression is quantified. Does this perturbation result in a significant change in GIPR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of AC006262.5. Does perturbing SAMD1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of AC006262.5. Does perturbing SAMD1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2340,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1113,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and C1orf228 expression is observed. Does this perturbation lead to a significant difference in C1orf228 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and C1orf228 expression is observed. Does this perturbation lead to a significant difference in C1orf228 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1420,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Does this perturbation cause a significant change in TRPM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Does this perturbation cause a significant change in TRPM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5490,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Does this perturbation cause a significant change in IGFL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Does this perturbation cause a significant change in IGFL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Determine whether TFRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Determine whether TFRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3733,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6128,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLEKHO1 expression. Decide whether this perturbation leads to a significant alteration in PLEKHO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLEKHO1 expression. Decide whether this perturbation leads to a significant alteration in PLEKHO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of SKAP2. Does perturbing LHX1 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of SKAP2. Does perturbing LHX1 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SLC20A1. Does perturbing PTPN1 lead to a significant change in SLC20A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SLC20A1. Does perturbing PTPN1 lead to a significant change in SLC20A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Determine whether RP5-1142A6.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Determine whether RP5-1142A6.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 46,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Determine whether RP11-445O3.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Determine whether RP11-445O3.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4053,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and PROX1 expression is observed. Does this perturbation lead to a significant difference in PROX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and PROX1 expression is observed. Does this perturbation lead to a significant difference in PROX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 0,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in AC020571.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in AC020571.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of BMP2K indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of BMP2K indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TUBA1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TUBA1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2158,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor NUDC expression. Decide whether this perturbation leads to a significant alteration in NUDC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor NUDC expression. Decide whether this perturbation leads to a significant alteration in NUDC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ADGB expression is quantified. Does this perturbation result in a significant change in ADGB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ADGB expression is quantified. Does this perturbation result in a significant change in ADGB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5948,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2363,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4648,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor CSRNP1 expression. Decide whether this perturbation leads to a significant alteration in CSRNP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor CSRNP1 expression. Decide whether this perturbation leads to a significant alteration in CSRNP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of DRC1. Does this perturbation cause a significant change in DRC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of DRC1. Does this perturbation cause a significant change in DRC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ATP8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ATP8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of FMNL1. Does perturbing HES7 lead to a significant change in FMNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of FMNL1. Does perturbing HES7 lead to a significant change in FMNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6070,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Does this perturbation cause a significant change in RP11-38J22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Does this perturbation cause a significant change in RP11-38J22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and LGALS12 expression is quantified. Does this perturbation result in a significant change in LGALS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and LGALS12 expression is quantified. Does this perturbation result in a significant change in LGALS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2582,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5798,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RP4-550H1.4 expression. Decide whether this perturbation leads to a significant alteration in RP4-550H1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RP4-550H1.4 expression. Decide whether this perturbation leads to a significant alteration in RP4-550H1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4173,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ABCA6 expression is observed. Does this perturbation lead to a significant difference in ABCA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ABCA6 expression is observed. Does this perturbation lead to a significant difference in ABCA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in FAM225B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in FAM225B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is quantified. Does this perturbation result in a significant change in HIPK1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is quantified. Does this perturbation result in a significant change in HIPK1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Determine whether PCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Determine whether PCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP6-159A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP6-159A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1568,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Determine whether PPFIA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Determine whether PPFIA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and XK expression is measured. Determine whether XK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and XK expression is measured. Determine whether XK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in HBE1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in HBE1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4280,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Does this perturbation cause a significant change in CITED2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Does this perturbation cause a significant change in CITED2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5491,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of IGFL2. Does perturbing TGFBR2 lead to a significant change in IGFL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of IGFL2. Does perturbing TGFBR2 lead to a significant change in IGFL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SDSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SDSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1433,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTD-3037G24.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3037G24.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTD-3037G24.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3037G24.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of MARCKS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of MARCKS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ZMYND15. Does this perturbation cause a significant change in ZMYND15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ZMYND15. Does this perturbation cause a significant change in ZMYND15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4728,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor WDR88 expression. Decide whether this perturbation leads to a significant alteration in WDR88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor WDR88 expression. Decide whether this perturbation leads to a significant alteration in WDR88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5533,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and MOGAT2 expression is observed. Does this perturbation lead to a significant difference in MOGAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and MOGAT2 expression is observed. Does this perturbation lead to a significant difference in MOGAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3248,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CD37 expression. Decide whether this perturbation leads to a significant alteration in CD37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CD37 expression. Decide whether this perturbation leads to a significant alteration in CD37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1118,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor C1orf228 expression. Decide whether this perturbation leads to a significant alteration in C1orf228 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor C1orf228 expression. Decide whether this perturbation leads to a significant alteration in C1orf228 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 650,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Does this perturbation cause a significant change in STRA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Does this perturbation cause a significant change in STRA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and YPEL3 expression is quantified. Does this perturbation result in a significant change in YPEL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and YPEL3 expression is quantified. Does this perturbation result in a significant change in YPEL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4528,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in YPEL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in YPEL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TMEM55A. Does this perturbation cause a significant change in TMEM55A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TMEM55A. Does this perturbation cause a significant change in TMEM55A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and SPTAN1 expression is measured. Determine whether SPTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and SPTAN1 expression is measured. Determine whether SPTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 450,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Does this perturbation cause a significant change in LINC01003 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Does this perturbation cause a significant change in LINC01003 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3388,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HHEX expression. Decide whether this perturbation leads to a significant alteration in HHEX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HHEX expression. Decide whether this perturbation leads to a significant alteration in HHEX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CENPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CENPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2023,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and CTSS expression is observed. Does this perturbation lead to a significant difference in CTSS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and CTSS expression is observed. Does this perturbation lead to a significant difference in CTSS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01395 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01395 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5013,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and TMEM35 expression is observed. Does this perturbation lead to a significant difference in TMEM35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and TMEM35 expression is observed. Does this perturbation lead to a significant difference in TMEM35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2470,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Does this perturbation cause a significant change in SOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Does this perturbation cause a significant change in SOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of TAPBP. Does perturbing MAP2K3 lead to a significant change in TAPBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of TAPBP. Does perturbing MAP2K3 lead to a significant change in TAPBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 348,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 470,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Does this perturbation cause a significant change in FAM49A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Does this perturbation cause a significant change in FAM49A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-109E24.2. Does this perturbation cause a significant change in RP11-109E24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-109E24.2. Does this perturbation cause a significant change in RP11-109E24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4158,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Determine whether TPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Determine whether TPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and CBL expression is quantified. Does this perturbation result in a significant change in CBL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and CBL expression is quantified. Does this perturbation result in a significant change in CBL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1308,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PCDHGA6 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PCDHGA6 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Determine whether APOBR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Determine whether APOBR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of SAT2. Does perturbing C19orf26 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of SAT2. Does perturbing C19orf26 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1952,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3093,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ZNF677 expression is observed. Does this perturbation lead to a significant difference in ZNF677 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ZNF677 expression is observed. Does this perturbation lead to a significant difference in ZNF677 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of VASH1. Does this perturbation cause a significant change in VASH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of VASH1. Does this perturbation cause a significant change in VASH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1098,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5201,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of TNFAIP2. Does perturbing CEBPB lead to a significant change in TNFAIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of TNFAIP2. Does perturbing CEBPB lead to a significant change in TNFAIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in TRGVA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in TRGVA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TFAP2A-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TFAP2A-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ID1. Does perturbing CBL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ID1. Does perturbing CBL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3044,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HCN1. Does this perturbation cause a significant change in HCN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HCN1. Does this perturbation cause a significant change in HCN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Determine whether MAOB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Determine whether MAOB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNDC3B. Does this perturbation cause a significant change in RUNDC3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNDC3B. Does this perturbation cause a significant change in RUNDC3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and RBM5-AS1 expression is quantified. Does this perturbation result in a significant change in RBM5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and RBM5-AS1 expression is quantified. Does this perturbation result in a significant change in RBM5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2688,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM83F expression. Decide whether this perturbation leads to a significant alteration in FAM83F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM83F expression. Decide whether this perturbation leads to a significant alteration in FAM83F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-510J16.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-510J16.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1082,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and SERPINF1 expression is quantified. Does this perturbation result in a significant change in SERPINF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and SERPINF1 expression is quantified. Does this perturbation result in a significant change in SERPINF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PHLDA2. Does perturbing ZBTB25 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PHLDA2. Does perturbing ZBTB25 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ST3GAL5. Does perturbing AHR lead to a significant change in ST3GAL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ST3GAL5. Does perturbing AHR lead to a significant change in ST3GAL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CTD-2527I21.14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CTD-2527I21.14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SAT1. Does perturbing FOXO4 lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SAT1. Does perturbing FOXO4 lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 932,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CYP2C18 expression is quantified. Does this perturbation result in a significant change in CYP2C18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CYP2C18 expression is quantified. Does this perturbation result in a significant change in CYP2C18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2430,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Does this perturbation cause a significant change in ZNF610 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Does this perturbation cause a significant change in ZNF610 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of RHOXF2BB. Does perturbing SLC38A2 lead to a significant change in RHOXF2BB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of RHOXF2BB. Does perturbing SLC38A2 lead to a significant change in RHOXF2BB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is measured. Determine whether COL18A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is measured. Determine whether COL18A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1810,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1928,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of FAM178B. Does perturbing AHR lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of FAM178B. Does perturbing AHR lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and TLCD2 expression is quantified. Does this perturbation result in a significant change in TLCD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and TLCD2 expression is quantified. Does this perturbation result in a significant change in TLCD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of CSRNP1. Does this perturbation cause a significant change in CSRNP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of CSRNP1. Does this perturbation cause a significant change in CSRNP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of SKAP2. Does perturbing OSR2 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of SKAP2. Does perturbing OSR2 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4363,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TFAP2A-AS1 expression is observed. Does this perturbation lead to a significant difference in TFAP2A-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TFAP2A-AS1 expression is observed. Does this perturbation lead to a significant difference in TFAP2A-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CKS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CKS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 744,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3974,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ARMCX3. Does this perturbation cause a significant change in ARMCX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ARMCX3. Does this perturbation cause a significant change in ARMCX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-514P8.2. Does this perturbation cause a significant change in RP11-514P8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-514P8.2. Does this perturbation cause a significant change in RP11-514P8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1803,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and CST9L expression is quantified. Does this perturbation result in a significant change in CST9L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and CST9L expression is quantified. Does this perturbation result in a significant change in CST9L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3373,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2830,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Does this perturbation cause a significant change in ANXA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Does this perturbation cause a significant change in ANXA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 36,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Determine whether PDE1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Determine whether PDE1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2545,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5351,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of GIPR. Does perturbing NIT1 lead to a significant change in GIPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of GIPR. Does perturbing NIT1 lead to a significant change in GIPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4737,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of MACF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of MACF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 680,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Does this perturbation cause a significant change in RAB5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Does this perturbation cause a significant change in RAB5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and TMEM154 expression is measured. Determine whether TMEM154 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and TMEM154 expression is measured. Determine whether TMEM154 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of FAM225B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of FAM225B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in RP11-537H15.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in RP11-537H15.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Determine whether ATP9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Determine whether ATP9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3933,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MS4A2 expression is observed. Does this perturbation lead to a significant difference in MS4A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MS4A2 expression is observed. Does this perturbation lead to a significant difference in MS4A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CENPE. Does perturbing CDKN1C lead to a significant change in CENPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CENPE. Does perturbing CDKN1C lead to a significant change in CENPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and DCAF13 expression is measured. Determine whether DCAF13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and DCAF13 expression is measured. Determine whether DCAF13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of TM4SF1-AS1. Does perturbing BPGM lead to a significant change in TM4SF1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of TM4SF1-AS1. Does perturbing BPGM lead to a significant change in TM4SF1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1668,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ABCB11 expression. Decide whether this perturbation leads to a significant alteration in ABCB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ABCB11 expression. Decide whether this perturbation leads to a significant alteration in ABCB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5280,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Does this perturbation cause a significant change in PSMB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Does this perturbation cause a significant change in PSMB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4464,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1982,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SNCG expression is quantified. Does this perturbation result in a significant change in SNCG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SNCG expression is quantified. Does this perturbation result in a significant change in SNCG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of LTC4S indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of LTC4S indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-563J2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-563J2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 73,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5580,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Does this perturbation cause a significant change in ANTXR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Does this perturbation cause a significant change in ANTXR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3483,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2983,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3163,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and PRKAG2-AS1 expression is observed. Does this perturbation lead to a significant difference in PRKAG2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and PRKAG2-AS1 expression is observed. Does this perturbation lead to a significant difference in PRKAG2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2348,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of MSRB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of MSRB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ACTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ACTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3155,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 828,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor AC007556.3 expression. Decide whether this perturbation leads to a significant alteration in AC007556.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor AC007556.3 expression. Decide whether this perturbation leads to a significant alteration in AC007556.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CCDC159 expression is measured. Determine whether CCDC159 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CCDC159 expression is measured. Determine whether CCDC159 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4533,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and RP11-244F12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-244F12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and RP11-244F12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-244F12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5138,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1430,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5403,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of AC064834.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of AC064834.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and CEBPA expression is measured. Determine whether CEBPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and CEBPA expression is measured. Determine whether CEBPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CTD-2031P19.5 expression is quantified. Does this perturbation result in a significant change in CTD-2031P19.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CTD-2031P19.5 expression is quantified. Does this perturbation result in a significant change in CTD-2031P19.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of FZD6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of FZD6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5340,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Does this perturbation cause a significant change in TOR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Does this perturbation cause a significant change in TOR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1288,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor COTL1 expression. Decide whether this perturbation leads to a significant alteration in COTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor COTL1 expression. Decide whether this perturbation leads to a significant alteration in COTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is quantified. Does this perturbation result in a significant change in CTB-49A3.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is quantified. Does this perturbation result in a significant change in CTB-49A3.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4793,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PAMR1 expression is observed. Does this perturbation lead to a significant difference in PAMR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PAMR1 expression is observed. Does this perturbation lead to a significant difference in PAMR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of PIM2. Does perturbing TBX3 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of PIM2. Does perturbing TBX3 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5010,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Does this perturbation cause a significant change in TMEM35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Does this perturbation cause a significant change in TMEM35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Determine whether TAPBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Determine whether TAPBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CPXM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CPXM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and KRT7 expression is quantified. Does this perturbation result in a significant change in KRT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and KRT7 expression is quantified. Does this perturbation result in a significant change in KRT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 460,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Does this perturbation cause a significant change in TRIM31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Does this perturbation cause a significant change in TRIM31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNDC3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNDC3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CRAT37. Does perturbing EGR1 lead to a significant change in CRAT37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CRAT37. Does perturbing EGR1 lead to a significant change in CRAT37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in S100A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in S100A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in MSX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in MSX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3833,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP3-510H16.3 expression is observed. Does this perturbation lead to a significant difference in RP3-510H16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP3-510H16.3 expression is observed. Does this perturbation lead to a significant difference in RP3-510H16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CTD-3126B10.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CTD-3126B10.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is quantified. Does this perturbation result in a significant change in PRKAG2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is quantified. Does this perturbation result in a significant change in PRKAG2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of CCDC136 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of CCDC136 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2160,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Does this perturbation cause a significant change in SPTAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Does this perturbation cause a significant change in SPTAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP6-159A1.4. Does this perturbation cause a significant change in RP6-159A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP6-159A1.4. Does this perturbation cause a significant change in RP6-159A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of SERPINF1. Does this perturbation cause a significant change in SERPINF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of SERPINF1. Does this perturbation cause a significant change in SERPINF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 687,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Determine whether CREB3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Determine whether CREB3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CRAT37 expression is quantified. Does this perturbation result in a significant change in CRAT37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CRAT37 expression is quantified. Does this perturbation result in a significant change in CRAT37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ACP5 expression is measured. Determine whether ACP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ACP5 expression is measured. Determine whether ACP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2708,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is quantified. Does this perturbation result in a significant change in RP11-52L5.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is quantified. Does this perturbation result in a significant change in RP11-52L5.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TFAP2A-AS1. Does perturbing KMT2A lead to a significant change in TFAP2A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TFAP2A-AS1. Does perturbing KMT2A lead to a significant change in TFAP2A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Determine whether TAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Determine whether TAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM118A. Does this perturbation cause a significant change in FAM118A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM118A. Does this perturbation cause a significant change in FAM118A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CYP3A5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CYP3A5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Determine whether CTC-492K19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Determine whether CTC-492K19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AC007246.3. Does this perturbation cause a significant change in AC007246.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AC007246.3. Does this perturbation cause a significant change in AC007246.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5318,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor EWSAT1 expression. Decide whether this perturbation leads to a significant alteration in EWSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor EWSAT1 expression. Decide whether this perturbation leads to a significant alteration in EWSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 858,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of AC020571.3. Does this perturbation cause a significant change in AC020571.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of AC020571.3. Does this perturbation cause a significant change in AC020571.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4676,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of COL21A1. Does this perturbation cause a significant change in COL21A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of COL21A1. Does this perturbation cause a significant change in COL21A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3808,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor TAC3 expression. Decide whether this perturbation leads to a significant alteration in TAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor TAC3 expression. Decide whether this perturbation leads to a significant alteration in TAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1003,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MBP expression is observed. Does this perturbation lead to a significant difference in MBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MBP expression is observed. Does this perturbation lead to a significant difference in MBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and KRT79 expression is quantified. Does this perturbation result in a significant change in KRT79 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and KRT79 expression is quantified. Does this perturbation result in a significant change in KRT79 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2943,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CRAT37. Does this perturbation cause a significant change in CRAT37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CRAT37. Does this perturbation cause a significant change in CRAT37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4903,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RP11-285F7.2 expression is observed. Does this perturbation lead to a significant difference in RP11-285F7.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RP11-285F7.2 expression is observed. Does this perturbation lead to a significant difference in RP11-285F7.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ST3GAL5 expression is quantified. Does this perturbation result in a significant change in ST3GAL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ST3GAL5 expression is quantified. Does this perturbation result in a significant change in ST3GAL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3563,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Determine whether S100A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Determine whether S100A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3130,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Does this perturbation cause a significant change in NUCB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Does this perturbation cause a significant change in NUCB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of RP11-244F12.2. Does this perturbation cause a significant change in RP11-244F12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of RP11-244F12.2. Does this perturbation cause a significant change in RP11-244F12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of RP11-714G18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of RP11-714G18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1043,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and S100A4 expression is observed. Does this perturbation lead to a significant difference in S100A4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and S100A4 expression is observed. Does this perturbation lead to a significant difference in S100A4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of WDR88. Does this perturbation cause a significant change in WDR88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of WDR88. Does this perturbation cause a significant change in WDR88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4598,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4188,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor RP11-362K14.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-362K14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor RP11-362K14.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-362K14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-514P8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-514P8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5820,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2668,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM118A expression. Decide whether this perturbation leads to a significant alteration in FAM118A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM118A expression. Decide whether this perturbation leads to a significant alteration in FAM118A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of RP11-445F12.1. Does this perturbation cause a significant change in RP11-445F12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of RP11-445F12.1. Does this perturbation cause a significant change in RP11-445F12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PSMB9. Does this perturbation cause a significant change in PSMB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PSMB9. Does this perturbation cause a significant change in PSMB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Determine whether ABCB11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Determine whether ABCB11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4260,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is measured. Determine whether RP11-452C8.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is measured. Determine whether RP11-452C8.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RUNX3 expression is measured. Determine whether RUNX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RUNX3 expression is measured. Determine whether RUNX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SLC2A3. Does perturbing IER5L lead to a significant change in SLC2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SLC2A3. Does perturbing IER5L lead to a significant change in SLC2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of RLN3. Does perturbing ZC3HAV1 lead to a significant change in RLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of RLN3. Does perturbing ZC3HAV1 lead to a significant change in RLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of TM4SF1-AS1. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of TM4SF1-AS1. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1068,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-510J16.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-510J16.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-510J16.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-510J16.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of TUBB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of TUBB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4837,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of NCALD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of NCALD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Determine whether MYL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Determine whether MYL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5920,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ATF6B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ATF6B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3562,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2320,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CCNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CCNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3792,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 508,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5683,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RHOH. Does perturbing ISL2 lead to a significant change in RHOH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RHOH. Does perturbing ISL2 lead to a significant change in RHOH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2478,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor SOX5 expression. Decide whether this perturbation leads to a significant alteration in SOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor SOX5 expression. Decide whether this perturbation leads to a significant alteration in SOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 468,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TRIM31 expression. Decide whether this perturbation leads to a significant alteration in TRIM31 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TRIM31 expression. Decide whether this perturbation leads to a significant alteration in TRIM31 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and MTURN expression is measured. Determine whether MTURN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and MTURN expression is measured. Determine whether MTURN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AC007246.3 expression is measured. Determine whether AC007246.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AC007246.3 expression is measured. Determine whether AC007246.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of PAQR7. Does perturbing LHX1 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of PAQR7. Does perturbing LHX1 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Determine whether RHOXF2BB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Determine whether RHOXF2BB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in MACF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in MACF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AMHR2. Does perturbing SLC38A2 lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AMHR2. Does perturbing SLC38A2 lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of TOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of TOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Determine whether TNFRSF12A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Determine whether TNFRSF12A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1999,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is measured. Determine whether SLC2A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is measured. Determine whether SLC2A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2960,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4258,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CCDC159 expression. Decide whether this perturbation leads to a significant alteration in CCDC159 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CCDC159 expression. Decide whether this perturbation leads to a significant alteration in CCDC159 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6041,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of NPW. Does perturbing HK2 lead to a significant change in NPW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of NPW. Does perturbing HK2 lead to a significant change in NPW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 25,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and RELB expression is quantified. Does this perturbation result in a significant change in RELB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and RELB expression is quantified. Does this perturbation result in a significant change in RELB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5675,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in EGOT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in EGOT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5873,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ANXA2R expression is observed. Does this perturbation lead to a significant difference in ANXA2R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ANXA2R expression is observed. Does this perturbation lead to a significant difference in ANXA2R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3753,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and TM4SF1-AS1 expression is observed. Does this perturbation lead to a significant difference in TM4SF1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and TM4SF1-AS1 expression is observed. Does this perturbation lead to a significant difference in TM4SF1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5120,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Does this perturbation cause a significant change in CCNJL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Does this perturbation cause a significant change in CCNJL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is measured. Determine whether CTD-2378E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is measured. Determine whether CTD-2378E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of APOBR. Does this perturbation cause a significant change in APOBR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of APOBR. Does this perturbation cause a significant change in APOBR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in TCAF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in TCAF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2128,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SDSL. Does perturbing PTPN1 lead to a significant change in SDSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SDSL. Does perturbing PTPN1 lead to a significant change in SDSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3633,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ATG2A expression is observed. Does this perturbation lead to a significant difference in ATG2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ATG2A expression is observed. Does this perturbation lead to a significant difference in ATG2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of DCAF13. Does this perturbation cause a significant change in DCAF13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of DCAF13. Does this perturbation cause a significant change in DCAF13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4118,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor RSPO4 expression. Decide whether this perturbation leads to a significant alteration in RSPO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor RSPO4 expression. Decide whether this perturbation leads to a significant alteration in RSPO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6218,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-109E24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-109E24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-109E24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-109E24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4233,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 645,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in CTA-384D8.34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in CTA-384D8.34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and WDR88 expression is measured. Determine whether WDR88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and WDR88 expression is measured. Determine whether WDR88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1278,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of SOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of SOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 801,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD52. Does perturbing ETS2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD52. Does perturbing ETS2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is quantified. Does this perturbation result in a significant change in RP11-76E17.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is quantified. Does this perturbation result in a significant change in RP11-76E17.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5383,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and HBG1 expression is observed. Does this perturbation lead to a significant difference in HBG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and HBG1 expression is observed. Does this perturbation lead to a significant difference in HBG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of RP11-38J22.3. Does this perturbation cause a significant change in RP11-38J22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of RP11-38J22.3. Does this perturbation cause a significant change in RP11-38J22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4373,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5021,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RNF213. Does perturbing OSR2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RNF213. Does perturbing OSR2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in KCNH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in KCNH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Determine whether AGXT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Determine whether AGXT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4040,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1820,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of PKIG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of PKIG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and HMGA2 expression is quantified. Does this perturbation result in a significant change in HMGA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and HMGA2 expression is quantified. Does this perturbation result in a significant change in HMGA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CACNA1C-AS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CACNA1C-AS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and MYC expression is measured. Determine whether MYC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and MYC expression is measured. Determine whether MYC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1335,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SDSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SDSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of APOBR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of APOBR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of LMNA. Does perturbing HES7 lead to a significant change in LMNA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of LMNA. Does perturbing HES7 lead to a significant change in LMNA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of COL1A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of COL1A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in DPYSL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in DPYSL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MS4A2 expression is measured. Determine whether MS4A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MS4A2 expression is measured. Determine whether MS4A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Determine whether RABAC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Determine whether RABAC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of CNN2. Does perturbing ARID1A lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of CNN2. Does perturbing ARID1A lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5256,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Determine whether UCKL1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Determine whether UCKL1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4148,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor TMEM154 expression. Decide whether this perturbation leads to a significant alteration in TMEM154 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor TMEM154 expression. Decide whether this perturbation leads to a significant alteration in TMEM154 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of PERM1. Does perturbing TGFBR2 lead to a significant change in PERM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of PERM1. Does perturbing TGFBR2 lead to a significant change in PERM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of FEV. Does perturbing TBX3 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of FEV. Does perturbing TBX3 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1913,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and S100A3 expression is observed. Does this perturbation lead to a significant difference in S100A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and S100A3 expression is observed. Does this perturbation lead to a significant difference in S100A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of RSPO4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of RSPO4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 962,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2434,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ZNF610. Does this perturbation cause a significant change in ZNF610 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ZNF610. Does this perturbation cause a significant change in ZNF610 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of HOXB6. Does perturbing ETS2 lead to a significant change in HOXB6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of HOXB6. Does perturbing ETS2 lead to a significant change in HOXB6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6001,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of TACC1. Does perturbing PRDM1 lead to a significant change in TACC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of TACC1. Does perturbing PRDM1 lead to a significant change in TACC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2473,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and SOX5 expression is observed. Does this perturbation lead to a significant difference in SOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and SOX5 expression is observed. Does this perturbation lead to a significant difference in SOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is quantified. Does this perturbation result in a significant change in RP3-525N10.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is quantified. Does this perturbation result in a significant change in RP3-525N10.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5358,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor GIPR expression. Decide whether this perturbation leads to a significant alteration in GIPR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor GIPR expression. Decide whether this perturbation leads to a significant alteration in GIPR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in FABP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in FABP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2068,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2833,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA2 expression is observed. Does this perturbation lead to a significant difference in ANXA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA2 expression is observed. Does this perturbation lead to a significant difference in ANXA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIPK1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIPK1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1818,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ACTC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ACTC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of TFRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of TFRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3990,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Does this perturbation cause a significant change in CLTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Does this perturbation cause a significant change in CLTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and DYNLT3 expression is quantified. Does this perturbation result in a significant change in DYNLT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and DYNLT3 expression is quantified. Does this perturbation result in a significant change in DYNLT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 712,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SKAP1 expression is quantified. Does this perturbation result in a significant change in SKAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SKAP1 expression is quantified. Does this perturbation result in a significant change in SKAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4133,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ITGA3 expression is observed. Does this perturbation lead to a significant difference in ITGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ITGA3 expression is observed. Does this perturbation lead to a significant difference in ITGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CTD-2378E12.1. Does perturbing CDKN1C lead to a significant change in CTD-2378E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CTD-2378E12.1. Does perturbing CDKN1C lead to a significant change in CTD-2378E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Determine whether HBG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Determine whether HBG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ATF6B expression is measured. Determine whether ATF6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ATF6B expression is measured. Determine whether ATF6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2693,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and RP11-91A18.4 expression is observed. Does this perturbation lead to a significant difference in RP11-91A18.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and RP11-91A18.4 expression is observed. Does this perturbation lead to a significant difference in RP11-91A18.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5600,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Does this perturbation cause a significant change in FCGR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Does this perturbation cause a significant change in FCGR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4766,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 770,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Does this perturbation cause a significant change in RNF168 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Does this perturbation cause a significant change in RNF168 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5525,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in SPARC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in SPARC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCDC148 expression is quantified. Does this perturbation result in a significant change in CCDC148 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCDC148 expression is quantified. Does this perturbation result in a significant change in CCDC148 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of RP11-195C7.1. Does this perturbation cause a significant change in RP11-195C7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of RP11-195C7.1. Does this perturbation cause a significant change in RP11-195C7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Determine whether HCAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Determine whether HCAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in IGHEP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in IGHEP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3560,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2138,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCDC148 expression. Decide whether this perturbation leads to a significant alteration in CCDC148 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCDC148 expression. Decide whether this perturbation leads to a significant alteration in CCDC148 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2798,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor KRT7 expression. Decide whether this perturbation leads to a significant alteration in KRT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor KRT7 expression. Decide whether this perturbation leads to a significant alteration in KRT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5103,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of APOL6. Does this perturbation cause a significant change in APOL6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of APOL6. Does this perturbation cause a significant change in APOL6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and STAC3 expression is quantified. Does this perturbation result in a significant change in STAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and STAC3 expression is quantified. Does this perturbation result in a significant change in STAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3730,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of DYNLT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of DYNLT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 763,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RP11-308D13.3 expression is observed. Does this perturbation lead to a significant difference in RP11-308D13.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RP11-308D13.3 expression is observed. Does this perturbation lead to a significant difference in RP11-308D13.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Determine whether LINC01358 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Determine whether LINC01358 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1066,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Determine whether RP11-510J16.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Determine whether RP11-510J16.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1173,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and RP11-355B11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-355B11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and RP11-355B11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-355B11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5388,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor HBG1 expression. Decide whether this perturbation leads to a significant alteration in HBG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor HBG1 expression. Decide whether this perturbation leads to a significant alteration in HBG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of TNFRSF12A. Does this perturbation cause a significant change in TNFRSF12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of TNFRSF12A. Does this perturbation cause a significant change in TNFRSF12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 735,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLAUR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLAUR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 160,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Does this perturbation cause a significant change in RBM5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Does this perturbation cause a significant change in RBM5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5068,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RP11-320G24.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-320G24.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RP11-320G24.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-320G24.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5163,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4558,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor SLC8A1 expression. Decide whether this perturbation leads to a significant alteration in SLC8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor SLC8A1 expression. Decide whether this perturbation leads to a significant alteration in SLC8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4958,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ASIC4. Does this perturbation cause a significant change in ASIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ASIC4. Does this perturbation cause a significant change in ASIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1169,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CDK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CDK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is measured. Determine whether RP11-244F12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is measured. Determine whether RP11-244F12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CTD-2012K14.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CTD-2012K14.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1945,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ORAI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ORAI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of STRC. Does perturbing HOXA13 lead to a significant change in STRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of STRC. Does perturbing HOXA13 lead to a significant change in STRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 977,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2903,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ADD3 expression is observed. Does this perturbation lead to a significant difference in ADD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ADD3 expression is observed. Does this perturbation lead to a significant difference in ADD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and RPS6KA2 expression is measured. Determine whether RPS6KA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and RPS6KA2 expression is measured. Determine whether RPS6KA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in INADL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in INADL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ZMAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ZMAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 69,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5404,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2646,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Determine whether TUBB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Determine whether TUBB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of FAM19A2. Does this perturbation cause a significant change in FAM19A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of FAM19A2. Does this perturbation cause a significant change in FAM19A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4328,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2884,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of CDC20. Does perturbing FOXO4 lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of CDC20. Does perturbing FOXO4 lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3910,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2743,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1413,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of TMEM88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of TMEM88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3360,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Does this perturbation cause a significant change in FAM19A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Does this perturbation cause a significant change in FAM19A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Determine whether PSMB8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Determine whether PSMB8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of MYO1F. Does this perturbation cause a significant change in MYO1F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of MYO1F. Does this perturbation cause a significant change in MYO1F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5263,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1219,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and AC020571.3 expression is measured. Determine whether AC020571.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and AC020571.3 expression is measured. Determine whether AC020571.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4590,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5758,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor YPEL3 expression. Decide whether this perturbation leads to a significant alteration in YPEL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor YPEL3 expression. Decide whether this perturbation leads to a significant alteration in YPEL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3500,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4807,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2718,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TUBA1A expression. Decide whether this perturbation leads to a significant alteration in TUBA1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TUBA1A expression. Decide whether this perturbation leads to a significant alteration in TUBA1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of HIST1H4H. Does this perturbation cause a significant change in HIST1H4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of HIST1H4H. Does this perturbation cause a significant change in HIST1H4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTC-492K19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTC-492K19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ZMYND15 expression is quantified. Does this perturbation result in a significant change in ZMYND15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ZMYND15 expression is quantified. Does this perturbation result in a significant change in ZMYND15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Determine whether TTC9B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Determine whether TTC9B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3798,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of UCKL1-AS1. Does perturbing CEBPB lead to a significant change in UCKL1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of UCKL1-AS1. Does perturbing CEBPB lead to a significant change in UCKL1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and CSRNP1 expression is measured. Determine whether CSRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and CSRNP1 expression is measured. Determine whether CSRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and CALY expression is quantified. Does this perturbation result in a significant change in CALY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and CALY expression is quantified. Does this perturbation result in a significant change in CALY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5168,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5804,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of DPYSL2. Does this perturbation cause a significant change in DPYSL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of DPYSL2. Does this perturbation cause a significant change in DPYSL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of DSC1. Does perturbing ZBTB25 lead to a significant change in DSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of DSC1. Does perturbing ZBTB25 lead to a significant change in DSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2370,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Does this perturbation cause a significant change in CD59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Does this perturbation cause a significant change in CD59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 102,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and PSMB8 expression is quantified. Does this perturbation result in a significant change in PSMB8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and PSMB8 expression is quantified. Does this perturbation result in a significant change in PSMB8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in RP11-244F12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in RP11-244F12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5973,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and HMOX1 expression is observed. Does this perturbation lead to a significant difference in HMOX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and HMOX1 expression is observed. Does this perturbation lead to a significant difference in HMOX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of CLTA. Does this perturbation cause a significant change in CLTA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of CLTA. Does this perturbation cause a significant change in CLTA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is measured. Determine whether RP11-362K14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is measured. Determine whether RP11-362K14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1318,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LINC01562 expression. Decide whether this perturbation leads to a significant alteration in LINC01562 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LINC01562 expression. Decide whether this perturbation leads to a significant alteration in LINC01562 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4768,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Determine whether RP11-286H15.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Determine whether RP11-286H15.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MS4A3. Does perturbing LHX1 lead to a significant change in MS4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MS4A3. Does perturbing LHX1 lead to a significant change in MS4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CARMN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CARMN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2670,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Does this perturbation cause a significant change in DYNLT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Does this perturbation cause a significant change in DYNLT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5118,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor KCNQ1-AS1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor KCNQ1-AS1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2775,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ACSL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ACSL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HCN1 expression is measured. Determine whether HCN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HCN1 expression is measured. Determine whether HCN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-505P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-505P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3183,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1643,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3440,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Does this perturbation cause a significant change in KCNH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Does this perturbation cause a significant change in KCNH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2289,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP3-510H16.3. Does this perturbation cause a significant change in RP3-510H16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP3-510H16.3. Does this perturbation cause a significant change in RP3-510H16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of DYNLL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of DYNLL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4710,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2870,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Does this perturbation cause a significant change in RP11-345P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Does this perturbation cause a significant change in RP11-345P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3543,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and DCAF13 expression is observed. Does this perturbation lead to a significant difference in DCAF13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and DCAF13 expression is observed. Does this perturbation lead to a significant difference in DCAF13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 912,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1388,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Determine whether SEMA3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Determine whether SEMA3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5078,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor LINC01338 expression. Decide whether this perturbation leads to a significant alteration in LINC01338 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor LINC01338 expression. Decide whether this perturbation leads to a significant alteration in LINC01338 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1929,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1648,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 250,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and SH3BGRL expression is measured. Determine whether SH3BGRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and SH3BGRL expression is measured. Determine whether SH3BGRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1045,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in S100A4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in S100A4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1577,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4179,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ABCA6 expression is measured. Determine whether ABCA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ABCA6 expression is measured. Determine whether ABCA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of GCM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of GCM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3976,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Determine whether ARMCX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Determine whether ARMCX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and TOR3A expression is measured. Determine whether TOR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and TOR3A expression is measured. Determine whether TOR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2892,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and FAM46C expression is quantified. Does this perturbation result in a significant change in FAM46C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and FAM46C expression is quantified. Does this perturbation result in a significant change in FAM46C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6002,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and TACC1 expression is quantified. Does this perturbation result in a significant change in TACC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and TACC1 expression is quantified. Does this perturbation result in a significant change in TACC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4703,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and CNN2 expression is observed. Does this perturbation lead to a significant difference in CNN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and CNN2 expression is observed. Does this perturbation lead to a significant difference in CNN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and INADL expression is measured. Determine whether INADL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and INADL expression is measured. Determine whether INADL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5605,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in FCGR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in FCGR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3188,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1574,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TPP1. Does this perturbation cause a significant change in TPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TPP1. Does this perturbation cause a significant change in TPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in CCDC136 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in CCDC136 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2910,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Does this perturbation cause a significant change in H1FNT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Does this perturbation cause a significant change in H1FNT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of RP11-244F12.2. Does perturbing TMSB4X lead to a significant change in RP11-244F12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of RP11-244F12.2. Does perturbing TMSB4X lead to a significant change in RP11-244F12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 227,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of DDX58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of DDX58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Does this perturbation cause a significant change in UNC5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Does this perturbation cause a significant change in UNC5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of RP11-91A18.4. Does perturbing TP73 lead to a significant change in RP11-91A18.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of RP11-91A18.4. Does perturbing TP73 lead to a significant change in RP11-91A18.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SOCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SOCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Determine whether INHBE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Determine whether INHBE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of AC004540.4. Does perturbing FOXL2 lead to a significant change in AC004540.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of AC004540.4. Does perturbing FOXL2 lead to a significant change in AC004540.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and RAB5B expression is quantified. Does this perturbation result in a significant change in RAB5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and RAB5B expression is quantified. Does this perturbation result in a significant change in RAB5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2053,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2108,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor MYB expression. Decide whether this perturbation leads to a significant alteration in MYB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor MYB expression. Decide whether this perturbation leads to a significant alteration in MYB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6113,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Determine whether RP11-505P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Determine whether RP11-505P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of PKIG. Does this perturbation cause a significant change in PKIG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of PKIG. Does this perturbation cause a significant change in PKIG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4610,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Does this perturbation cause a significant change in PPP4R4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Does this perturbation cause a significant change in PPP4R4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 451,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of LINC01003. Does perturbing MEIS1 lead to a significant change in LINC01003 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of LINC01003. Does perturbing MEIS1 lead to a significant change in LINC01003 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Determine whether ZMYND15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Determine whether ZMYND15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6138,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5983,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3043,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HCN1 expression is observed. Does this perturbation lead to a significant difference in HCN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HCN1 expression is observed. Does this perturbation lead to a significant difference in HCN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SOCS2. Does this perturbation cause a significant change in SOCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SOCS2. Does this perturbation cause a significant change in SOCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3530,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Does this perturbation cause a significant change in C1orf162 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Does this perturbation cause a significant change in C1orf162 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of SLC8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of SLC8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of RIMBP3C. Does this perturbation cause a significant change in RIMBP3C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of RIMBP3C. Does this perturbation cause a significant change in RIMBP3C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3087,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2190,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Does this perturbation cause a significant change in IL1RN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Does this perturbation cause a significant change in IL1RN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4640,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Does this perturbation cause a significant change in CSRNP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Does this perturbation cause a significant change in CSRNP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ARHGEF6 expression is measured. Determine whether ARHGEF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ARHGEF6 expression is measured. Determine whether ARHGEF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4523,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1628,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor MKNK2 expression. Decide whether this perturbation leads to a significant alteration in MKNK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor MKNK2 expression. Decide whether this perturbation leads to a significant alteration in MKNK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCM2L expression is quantified. Does this perturbation result in a significant change in CCM2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCM2L expression is quantified. Does this perturbation result in a significant change in CCM2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of RP11-635N19.1. Does perturbing MAP4K5 lead to a significant change in RP11-635N19.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of RP11-635N19.1. Does perturbing MAP4K5 lead to a significant change in RP11-635N19.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in FAM46C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in FAM46C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5158,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of AC004051.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of AC004051.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1813,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5100,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-567N4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-567N4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ADGB. Does this perturbation cause a significant change in ADGB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ADGB. Does this perturbation cause a significant change in ADGB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 738,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLAUR expression. Decide whether this perturbation leads to a significant alteration in PLAUR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLAUR expression. Decide whether this perturbation leads to a significant alteration in PLAUR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of HBD. Does perturbing SPI1 lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of HBD. Does perturbing SPI1 lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is quantified. Does this perturbation result in a significant change in CTA-384D8.34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is quantified. Does this perturbation result in a significant change in CTA-384D8.34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of RP1-59D14.10. Does this perturbation cause a significant change in RP1-59D14.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of RP1-59D14.10. Does this perturbation cause a significant change in RP1-59D14.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 276,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Determine whether STAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Determine whether STAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5608,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor FCGR3A expression. Decide whether this perturbation leads to a significant alteration in FCGR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor FCGR3A expression. Decide whether this perturbation leads to a significant alteration in FCGR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ANTXR2 expression is measured. Determine whether ANTXR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ANTXR2 expression is measured. Determine whether ANTXR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 580,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Does this perturbation cause a significant change in ETS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Does this perturbation cause a significant change in ETS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in RIMBP3C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in RIMBP3C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1992,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is quantified. Does this perturbation result in a significant change in SLC2A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is quantified. Does this perturbation result in a significant change in SLC2A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 598,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor AC144568.2 expression. Decide whether this perturbation leads to a significant alteration in AC144568.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor AC144568.2 expression. Decide whether this perturbation leads to a significant alteration in AC144568.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Determine whether TRPM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Determine whether TRPM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of SH3RF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of SH3RF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5783,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and INHBE expression is observed. Does this perturbation lead to a significant difference in INHBE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and INHBE expression is observed. Does this perturbation lead to a significant difference in INHBE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4960,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1853,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and RP11-714G18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-714G18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and RP11-714G18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-714G18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Determine whether CLTA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Determine whether CLTA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of BCL2L11. Does perturbing BCL2L11 lead to a significant change in BCL2L11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of BCL2L11. Does perturbing BCL2L11 lead to a significant change in BCL2L11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of AC004540.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of AC004540.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of IGFL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of IGFL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6232,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1842,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and AC004051.2 expression is quantified. Does this perturbation result in a significant change in AC004051.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and AC004051.2 expression is quantified. Does this perturbation result in a significant change in AC004051.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5678,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor EGOT expression. Decide whether this perturbation leads to a significant alteration in EGOT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor EGOT expression. Decide whether this perturbation leads to a significant alteration in EGOT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1558,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ATP8B4 expression. Decide whether this perturbation leads to a significant alteration in ATP8B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ATP8B4 expression. Decide whether this perturbation leads to a significant alteration in ATP8B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Determine whether STRA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Determine whether STRA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2550,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Does this perturbation cause a significant change in RP11-505P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Does this perturbation cause a significant change in RP11-505P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1938,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of SIGLEC15. Does this perturbation cause a significant change in SIGLEC15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of SIGLEC15. Does this perturbation cause a significant change in SIGLEC15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LRRC74B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LRRC74B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2225,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is measured. Determine whether CTD-2616J11.16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is measured. Determine whether CTD-2616J11.16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4348,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor HIST1H4H expression. Decide whether this perturbation leads to a significant alteration in HIST1H4H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor HIST1H4H expression. Decide whether this perturbation leads to a significant alteration in HIST1H4H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4765,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3200,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ATG2A. Does this perturbation cause a significant change in ATG2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ATG2A. Does this perturbation cause a significant change in ATG2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 520,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Does this perturbation cause a significant change in RP11-83A24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Does this perturbation cause a significant change in RP11-83A24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Determine whether DCAF13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Determine whether DCAF13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1788,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-567N4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-567N4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-567N4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-567N4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4748,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ICAM4 expression. Decide whether this perturbation leads to a significant alteration in ICAM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ICAM4 expression. Decide whether this perturbation leads to a significant alteration in ICAM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM118A expression is measured. Determine whether FAM118A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM118A expression is measured. Determine whether FAM118A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2888,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2028,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor CTSS expression. Decide whether this perturbation leads to a significant alteration in CTSS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor CTSS expression. Decide whether this perturbation leads to a significant alteration in CTSS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 21,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RNF213. Does perturbing TSC22D1 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RNF213. Does perturbing TSC22D1 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ATP9A expression is quantified. Does this perturbation result in a significant change in ATP9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ATP9A expression is quantified. Does this perturbation result in a significant change in ATP9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTD-3037G24.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTD-3037G24.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in AC007556.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in AC007556.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1550,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Does this perturbation cause a significant change in ATP8B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Does this perturbation cause a significant change in ATP8B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4163,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ATP9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ATP9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1772,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-219B4.7 expression is quantified. Does this perturbation result in a significant change in RP11-219B4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-219B4.7 expression is quantified. Does this perturbation result in a significant change in RP11-219B4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of CRABP2. Does perturbing ELMSAN1 lead to a significant change in CRABP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of CRABP2. Does perturbing ELMSAN1 lead to a significant change in CRABP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CMB9-22P13.1. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CMB9-22P13.1. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Determine whether RP11-362K14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Determine whether RP11-362K14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1158,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of AC064834.2. Does perturbing PTPN1 lead to a significant change in AC064834.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of AC064834.2. Does perturbing PTPN1 lead to a significant change in AC064834.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3018,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PCDHGA6. Does this perturbation cause a significant change in PCDHGA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PCDHGA6. Does this perturbation cause a significant change in PCDHGA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2342,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3033,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and EMP3 expression is observed. Does this perturbation lead to a significant difference in EMP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and EMP3 expression is observed. Does this perturbation lead to a significant difference in EMP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in PLEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in PLEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CHI3L2. Does perturbing PRDM1 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CHI3L2. Does perturbing PRDM1 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 408,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CTD-2311M21.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2311M21.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CTD-2311M21.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2311M21.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5773,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RPL17-C18orf32 expression is observed. Does this perturbation lead to a significant difference in RPL17-C18orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RPL17-C18orf32 expression is observed. Does this perturbation lead to a significant difference in RPL17-C18orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is measured. Determine whether RP11-180M15.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is measured. Determine whether RP11-180M15.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 883,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CTD-2031P19.5 expression is observed. Does this perturbation lead to a significant difference in CTD-2031P19.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CTD-2031P19.5 expression is observed. Does this perturbation lead to a significant difference in CTD-2031P19.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4933,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and CPVL expression is observed. Does this perturbation lead to a significant difference in CPVL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and CPVL expression is observed. Does this perturbation lead to a significant difference in CPVL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 258,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and RPS6KA2 expression is quantified. Does this perturbation result in a significant change in RPS6KA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and RPS6KA2 expression is quantified. Does this perturbation result in a significant change in RPS6KA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and SLC31A2 expression is measured. Determine whether SLC31A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and SLC31A2 expression is measured. Determine whether SLC31A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2823,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP6-159A1.4 expression is observed. Does this perturbation lead to a significant difference in RP6-159A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP6-159A1.4 expression is observed. Does this perturbation lead to a significant difference in RP6-159A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1258,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-497G19.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-497G19.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-497G19.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-497G19.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is measured. Determine whether CTD-3126B10.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is measured. Determine whether CTD-3126B10.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4757,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of COL18A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of COL18A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SOCS2 expression is measured. Determine whether SOCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SOCS2 expression is measured. Determine whether SOCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of HCAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of HCAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of PRKCB. Does perturbing CSRNP1 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of PRKCB. Does perturbing CSRNP1 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in HIST1H4H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in HIST1H4H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1623,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and MKNK2 expression is observed. Does this perturbation lead to a significant difference in MKNK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and MKNK2 expression is observed. Does this perturbation lead to a significant difference in MKNK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1478,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of VCX3B. Does this perturbation cause a significant change in VCX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of VCX3B. Does this perturbation cause a significant change in VCX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CTD-3126B10.4. Does perturbing CDKN1A lead to a significant change in CTD-3126B10.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CTD-3126B10.4. Does perturbing CDKN1A lead to a significant change in CTD-3126B10.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of LPAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of LPAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 98,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor TDRD12 expression. Decide whether this perturbation leads to a significant alteration in TDRD12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor TDRD12 expression. Decide whether this perturbation leads to a significant alteration in TDRD12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of COL1A1. Does this perturbation cause a significant change in COL1A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of COL1A1. Does this perturbation cause a significant change in COL1A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 753,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLA2G1B expression is observed. Does this perturbation lead to a significant difference in PLA2G1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLA2G1B expression is observed. Does this perturbation lead to a significant difference in PLA2G1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6085,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in SLC4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in SLC4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3853,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CCNB1 expression is observed. Does this perturbation lead to a significant difference in CCNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CCNB1 expression is observed. Does this perturbation lead to a significant difference in CCNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of CD24. Does perturbing ZBTB1 lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of CD24. Does perturbing ZBTB1 lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1620,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Does this perturbation cause a significant change in MKNK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Does this perturbation cause a significant change in MKNK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2806,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Determine whether RUNDC3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Determine whether RUNDC3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5933,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and LBH expression is observed. Does this perturbation lead to a significant difference in LBH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and LBH expression is observed. Does this perturbation lead to a significant difference in LBH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2330,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Does this perturbation cause a significant change in C1orf141 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Does this perturbation cause a significant change in C1orf141 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2763,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and IER3 expression is observed. Does this perturbation lead to a significant difference in IER3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and IER3 expression is observed. Does this perturbation lead to a significant difference in IER3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4223,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and N4BP2L2 expression is observed. Does this perturbation lead to a significant difference in N4BP2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and N4BP2L2 expression is observed. Does this perturbation lead to a significant difference in N4BP2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of HEMGN. Does perturbing RUNX1T1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of HEMGN. Does perturbing RUNX1T1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RABGAP1L. Does perturbing GLB1L2 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RABGAP1L. Does perturbing GLB1L2 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TPM4. Does perturbing TMSB4X lead to a significant change in TPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TPM4. Does perturbing TMSB4X lead to a significant change in TPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is quantified. Does this perturbation result in a significant change in TM4SF1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is quantified. Does this perturbation result in a significant change in TM4SF1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6200,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Does this perturbation cause a significant change in RP11-52L5.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Does this perturbation cause a significant change in RP11-52L5.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6088,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor SLC4A3 expression. Decide whether this perturbation leads to a significant alteration in SLC4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor SLC4A3 expression. Decide whether this perturbation leads to a significant alteration in SLC4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4054,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of PROX1. Does this perturbation cause a significant change in PROX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of PROX1. Does this perturbation cause a significant change in PROX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 629,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and IFIT2 expression is quantified. Does this perturbation result in a significant change in IFIT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and IFIT2 expression is quantified. Does this perturbation result in a significant change in IFIT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4588,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor FNDC3A expression. Decide whether this perturbation leads to a significant alteration in FNDC3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor FNDC3A expression. Decide whether this perturbation leads to a significant alteration in FNDC3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4128,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor AC004540.4 expression. Decide whether this perturbation leads to a significant alteration in AC004540.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor AC004540.4 expression. Decide whether this perturbation leads to a significant alteration in AC004540.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of DLX4. Does perturbing EGR1 lead to a significant change in DLX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of DLX4. Does perturbing EGR1 lead to a significant change in DLX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Determine whether ATG2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Determine whether ATG2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4594,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4553,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and SLC8A1 expression is observed. Does this perturbation lead to a significant difference in SLC8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and SLC8A1 expression is observed. Does this perturbation lead to a significant difference in SLC8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1584,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of VGF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of VGF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CYP3A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CYP3A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2338,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor C1orf141 expression. Decide whether this perturbation leads to a significant alteration in C1orf141 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor C1orf141 expression. Decide whether this perturbation leads to a significant alteration in C1orf141 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of AC007556.3. Does this perturbation cause a significant change in AC007556.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of AC007556.3. Does this perturbation cause a significant change in AC007556.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RP11-83A24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RP11-83A24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is quantified. Does this perturbation result in a significant change in RP11-83A24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is quantified. Does this perturbation result in a significant change in RP11-83A24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in C1orf162 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in C1orf162 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCDC148. Does this perturbation cause a significant change in CCDC148 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCDC148. Does this perturbation cause a significant change in CCDC148 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4536,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Determine whether RP11-244F12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Determine whether RP11-244F12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RHOH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RHOH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4510,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Does this perturbation cause a significant change in TPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Does this perturbation cause a significant change in TPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3380,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Does this perturbation cause a significant change in HHEX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Does this perturbation cause a significant change in HHEX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Determine whether ZNF85 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Determine whether ZNF85 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Determine whether SLC7A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Determine whether SLC7A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Determine whether RP11-445F12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Determine whether RP11-445F12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Determine whether TUBA1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Determine whether TUBA1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of MARCKS. Does this perturbation cause a significant change in MARCKS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of MARCKS. Does this perturbation cause a significant change in MARCKS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of CTB-49A3.5. Does this perturbation cause a significant change in CTB-49A3.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of CTB-49A3.5. Does this perturbation cause a significant change in CTB-49A3.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4863,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4203,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3797,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CREB3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CREB3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1013,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is quantified. Does this perturbation result in a significant change in RP11-362K14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is quantified. Does this perturbation result in a significant change in RP11-362K14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Determine whether FLJ12825 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Determine whether FLJ12825 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of PTPRS. Does this perturbation cause a significant change in PTPRS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of PTPRS. Does this perturbation cause a significant change in PTPRS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5320,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Does this perturbation cause a significant change in ATF6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Does this perturbation cause a significant change in ATF6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1495,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in MAOB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in MAOB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of CCNG2. Does perturbing SGK1 lead to a significant change in CCNG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of CCNG2. Does perturbing SGK1 lead to a significant change in CCNG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4538,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor RP11-244F12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-244F12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor RP11-244F12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-244F12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3480,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Determine whether RP11-290L1.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Determine whether RP11-290L1.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 930,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Does this perturbation cause a significant change in CYP2C18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Does this perturbation cause a significant change in CYP2C18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2818,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor DYNLL1 expression. Decide whether this perturbation leads to a significant alteration in DYNLL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor DYNLL1 expression. Decide whether this perturbation leads to a significant alteration in DYNLL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4358,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor SLCO6A1 expression. Decide whether this perturbation leads to a significant alteration in SLCO6A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor SLCO6A1 expression. Decide whether this perturbation leads to a significant alteration in SLCO6A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in HBG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in HBG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Determine whether RP1-261G23.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Determine whether RP1-261G23.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01227 expression is measured. Determine whether LINC01227 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01227 expression is measured. Determine whether LINC01227 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 657,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of STRA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of STRA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4126,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Determine whether AC004540.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Determine whether AC004540.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5721,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ADGRF1. Does perturbing SLC38A2 lead to a significant change in ADGRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ADGRF1. Does perturbing SLC38A2 lead to a significant change in ADGRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of RP11-355B11.2. Does this perturbation cause a significant change in RP11-355B11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of RP11-355B11.2. Does this perturbation cause a significant change in RP11-355B11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and CCDC136 expression is quantified. Does this perturbation result in a significant change in CCDC136 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and CCDC136 expression is quantified. Does this perturbation result in a significant change in CCDC136 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4352,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and SLCO6A1 expression is quantified. Does this perturbation result in a significant change in SLCO6A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and SLCO6A1 expression is quantified. Does this perturbation result in a significant change in SLCO6A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4088,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4887,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3467,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SPANXN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SPANXN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5900,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Does this perturbation cause a significant change in STRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Does this perturbation cause a significant change in STRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Determine whether REEP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Determine whether REEP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of LBH. Does perturbing CITED1 lead to a significant change in LBH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of LBH. Does perturbing CITED1 lead to a significant change in LBH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5717,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of RHOXF2BB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of RHOXF2BB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6103,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5538,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor MOGAT2 expression. Decide whether this perturbation leads to a significant alteration in MOGAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor MOGAT2 expression. Decide whether this perturbation leads to a significant alteration in MOGAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCDC148. Does perturbing CNN1 lead to a significant change in CCDC148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCDC148. Does perturbing CNN1 lead to a significant change in CCDC148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5343,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and TOR3A expression is observed. Does this perturbation lead to a significant difference in TOR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and TOR3A expression is observed. Does this perturbation lead to a significant difference in TOR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3922,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and GPR35 expression is quantified. Does this perturbation result in a significant change in GPR35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and GPR35 expression is quantified. Does this perturbation result in a significant change in GPR35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 486,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1570,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6236,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ITGA3. Does this perturbation cause a significant change in ITGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ITGA3. Does this perturbation cause a significant change in ITGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Determine whether RP6-159A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Determine whether RP6-159A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of RASGRF2. Does this perturbation cause a significant change in RASGRF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of RASGRF2. Does this perturbation cause a significant change in RASGRF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6264,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of MME. Does this perturbation cause a significant change in MME expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of MME. Does this perturbation cause a significant change in MME expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of REEP6. Does this perturbation cause a significant change in REEP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of REEP6. Does this perturbation cause a significant change in REEP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ITGA3 expression is quantified. Does this perturbation result in a significant change in ITGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ITGA3 expression is quantified. Does this perturbation result in a significant change in ITGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ASIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ASIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RP11-308D13.3. Does this perturbation cause a significant change in RP11-308D13.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RP11-308D13.3. Does this perturbation cause a significant change in RP11-308D13.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of RP11-202A13.1. Does perturbing CNNM4 lead to a significant change in RP11-202A13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of RP11-202A13.1. Does perturbing CNNM4 lead to a significant change in RP11-202A13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3328,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1893,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C8orf22 expression is observed. Does this perturbation lead to a significant difference in C8orf22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C8orf22 expression is observed. Does this perturbation lead to a significant difference in C8orf22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5207,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of TNFAIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of TNFAIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 173,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and FLJ12825 expression is observed. Does this perturbation lead to a significant difference in FLJ12825 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and FLJ12825 expression is observed. Does this perturbation lead to a significant difference in FLJ12825 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Determine whether CCDC148 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Determine whether CCDC148 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5213,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CTD-2012K14.6 expression is observed. Does this perturbation lead to a significant difference in CTD-2012K14.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CTD-2012K14.6 expression is observed. Does this perturbation lead to a significant difference in CTD-2012K14.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2560,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Does this perturbation cause a significant change in PCDHGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Does this perturbation cause a significant change in PCDHGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3907,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of TNFRSF12A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of TNFRSF12A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of CTA-384D8.34. Does this perturbation cause a significant change in CTA-384D8.34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of CTA-384D8.34. Does this perturbation cause a significant change in CTA-384D8.34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2443,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and AC064834.2 expression is observed. Does this perturbation lead to a significant difference in AC064834.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and AC064834.2 expression is observed. Does this perturbation lead to a significant difference in AC064834.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 762,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RP11-308D13.3 expression is quantified. Does this perturbation result in a significant change in RP11-308D13.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RP11-308D13.3 expression is quantified. Does this perturbation result in a significant change in RP11-308D13.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in PHACTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in PHACTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5450,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2092,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ABCA13 expression is quantified. Does this perturbation result in a significant change in ABCA13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ABCA13 expression is quantified. Does this perturbation result in a significant change in ABCA13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5763,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of RP11-6D1.3. Does perturbing MAP2K6 lead to a significant change in RP11-6D1.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of RP11-6D1.3. Does perturbing MAP2K6 lead to a significant change in RP11-6D1.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and NUMB expression is measured. Determine whether NUMB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and NUMB expression is measured. Determine whether NUMB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01420 expression is measured. Determine whether LINC01420 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01420 expression is measured. Determine whether LINC01420 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ATF6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ATF6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2773,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ACSL1 expression is observed. Does this perturbation lead to a significant difference in ACSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ACSL1 expression is observed. Does this perturbation lead to a significant difference in ACSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4633,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 903,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5398,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CMB9-22P13.1 expression. Decide whether this perturbation leads to a significant alteration in CMB9-22P13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CMB9-22P13.1 expression. Decide whether this perturbation leads to a significant alteration in CMB9-22P13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Determine whether HSD17B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Determine whether HSD17B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CACNA1C-AS2. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CACNA1C-AS2. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is quantified. Does this perturbation result in a significant change in CTD-2527I21.14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is quantified. Does this perturbation result in a significant change in CTD-2527I21.14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is measured. Determine whether RP11-510J16.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is measured. Determine whether RP11-510J16.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of IL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of IL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3671,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ZFP36L2. Does perturbing PLK4 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ZFP36L2. Does perturbing PLK4 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of SIGLEC15. Does perturbing RUNX1T1 lead to a significant change in SIGLEC15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of SIGLEC15. Does perturbing RUNX1T1 lead to a significant change in SIGLEC15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2610,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Does this perturbation cause a significant change in ZIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Does this perturbation cause a significant change in ZIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TPM4. Does this perturbation cause a significant change in TPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TPM4. Does this perturbation cause a significant change in TPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 158,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor VCX3B expression. Decide whether this perturbation leads to a significant alteration in VCX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor VCX3B expression. Decide whether this perturbation leads to a significant alteration in VCX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Determine whether GPR35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Determine whether GPR35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1353,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and GCM2 expression is observed. Does this perturbation lead to a significant difference in GCM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and GCM2 expression is observed. Does this perturbation lead to a significant difference in GCM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-219B4.7. Does this perturbation cause a significant change in RP11-219B4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-219B4.7. Does this perturbation cause a significant change in RP11-219B4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in LINC00479 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in LINC00479 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2919,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and H1FNT expression is measured. Determine whether H1FNT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and H1FNT expression is measured. Determine whether H1FNT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4298,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AC034228.4 expression. Decide whether this perturbation leads to a significant alteration in AC034228.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AC034228.4 expression. Decide whether this perturbation leads to a significant alteration in AC034228.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 473,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and FAM49A expression is observed. Does this perturbation lead to a significant difference in FAM49A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and FAM49A expression is observed. Does this perturbation lead to a significant difference in FAM49A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1903,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and RP1-261G23.7 expression is observed. Does this perturbation lead to a significant difference in RP1-261G23.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and RP1-261G23.7 expression is observed. Does this perturbation lead to a significant difference in RP1-261G23.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 198,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1538,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor SLC43A2 expression. Decide whether this perturbation leads to a significant alteration in SLC43A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor SLC43A2 expression. Decide whether this perturbation leads to a significant alteration in SLC43A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5653,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and RELB expression is observed. Does this perturbation lead to a significant difference in RELB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and RELB expression is observed. Does this perturbation lead to a significant difference in RELB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP3-467K16.2. Does perturbing PLK4 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP3-467K16.2. Does perturbing PLK4 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ANXA2R expression is quantified. Does this perturbation result in a significant change in ANXA2R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ANXA2R expression is quantified. Does this perturbation result in a significant change in ANXA2R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1448,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1440,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 88,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5500,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4030,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Does this perturbation cause a significant change in MSX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Does this perturbation cause a significant change in MSX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3060,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 94,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of TDRD12. Does this perturbation cause a significant change in TDRD12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of TDRD12. Does this perturbation cause a significant change in TDRD12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of SSTR3. Does this perturbation cause a significant change in SSTR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of SSTR3. Does this perturbation cause a significant change in SSTR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 542,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Determine whether PTPRS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Determine whether PTPRS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5553,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and TLCD2 expression is observed. Does this perturbation lead to a significant difference in TLCD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and TLCD2 expression is observed. Does this perturbation lead to a significant difference in TLCD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 636,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Determine whether COL18A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Determine whether COL18A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4421,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of COL21A1. Does perturbing IGDCC3 lead to a significant change in COL21A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of COL21A1. Does perturbing IGDCC3 lead to a significant change in COL21A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2908,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ADD3 expression. Decide whether this perturbation leads to a significant alteration in ADD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ADD3 expression. Decide whether this perturbation leads to a significant alteration in ADD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2567,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of PCDHGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of PCDHGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4694,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 677,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5811,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LGALS1. Does perturbing SNAI1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LGALS1. Does perturbing SNAI1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CYP1B1-AS1. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CYP1B1-AS1. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1234,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of MYLIP. Does this perturbation cause a significant change in MYLIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of MYLIP. Does this perturbation cause a significant change in MYLIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5007,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of RLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of RLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of CCNG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of CCNG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3968,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ANXA3 expression. Decide whether this perturbation leads to a significant alteration in ANXA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ANXA3 expression. Decide whether this perturbation leads to a significant alteration in ANXA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RP4-550H1.4. Does this perturbation cause a significant change in RP4-550H1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RP4-550H1.4. Does this perturbation cause a significant change in RP4-550H1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Determine whether CTD-2031P19.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Determine whether CTD-2031P19.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 973,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and LRRC36 expression is measured. Determine whether LRRC36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and LRRC36 expression is measured. Determine whether LRRC36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4569,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Determine whether COL21A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Determine whether COL21A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3779,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and RP1-59D14.10 expression is measured. Determine whether RP1-59D14.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and RP1-59D14.10 expression is measured. Determine whether RP1-59D14.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5181,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of TMEM88. Does perturbing STIL lead to a significant change in TMEM88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of TMEM88. Does perturbing STIL lead to a significant change in TMEM88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and AC145110.1 expression is quantified. Does this perturbation result in a significant change in AC145110.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and AC145110.1 expression is quantified. Does this perturbation result in a significant change in AC145110.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 673,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5968,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RGPD5 expression. Decide whether this perturbation leads to a significant alteration in RGPD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RGPD5 expression. Decide whether this perturbation leads to a significant alteration in RGPD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is measured. Determine whether RP4-565E6.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is measured. Determine whether RP4-565E6.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3960,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Does this perturbation cause a significant change in ANXA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Does this perturbation cause a significant change in ANXA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RNF168 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RNF168 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 560,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2091,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ABCA13. Does perturbing POU3F2 lead to a significant change in ABCA13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ABCA13. Does perturbing POU3F2 lead to a significant change in ABCA13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CCNB1 expression is quantified. Does this perturbation result in a significant change in CCNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CCNB1 expression is quantified. Does this perturbation result in a significant change in CCNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2103,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and MYB expression is observed. Does this perturbation lead to a significant difference in MYB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and MYB expression is observed. Does this perturbation lead to a significant difference in MYB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5964,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RGPD5. Does this perturbation cause a significant change in RGPD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RGPD5. Does this perturbation cause a significant change in RGPD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Determine whether CAPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Determine whether CAPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6178,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of CRYAB. Does perturbing MAP4K5 lead to a significant change in CRYAB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of CRYAB. Does perturbing MAP4K5 lead to a significant change in CRYAB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4820,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of TMEM88. Does this perturbation cause a significant change in TMEM88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of TMEM88. Does this perturbation cause a significant change in TMEM88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 64,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Determine whether RP11-1017G21.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Determine whether RP11-1017G21.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Determine whether RP11-968A15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Determine whether RP11-968A15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of S100A13. Does perturbing FOXO4 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of S100A13. Does perturbing FOXO4 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in TNFAIP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in TNFAIP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of PERM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of PERM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4733,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and MACF1 expression is observed. Does this perturbation lead to a significant difference in MACF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and MACF1 expression is observed. Does this perturbation lead to a significant difference in MACF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of AKAP13. Does this perturbation cause a significant change in AKAP13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of AKAP13. Does this perturbation cause a significant change in AKAP13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5771,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RPL17-C18orf32. Does perturbing PTPN9 lead to a significant change in RPL17-C18orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RPL17-C18orf32. Does perturbing PTPN9 lead to a significant change in RPL17-C18orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 683,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and RAB5B expression is observed. Does this perturbation lead to a significant difference in RAB5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and RAB5B expression is observed. Does this perturbation lead to a significant difference in RAB5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and DPYSL2 expression is quantified. Does this perturbation result in a significant change in DPYSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and DPYSL2 expression is quantified. Does this perturbation result in a significant change in DPYSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Determine whether DSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Determine whether DSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4585,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in FNDC3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in FNDC3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4870,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Does this perturbation cause a significant change in CAPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Does this perturbation cause a significant change in CAPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3961,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ANXA3. Does perturbing MAP2K6 lead to a significant change in ANXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ANXA3. Does perturbing MAP2K6 lead to a significant change in ANXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1591,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of CALY. Does perturbing DLX2 lead to a significant change in CALY expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of CALY. Does perturbing DLX2 lead to a significant change in CALY expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4448,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP1B1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP1B1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5628,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FAM83A expression. Decide whether this perturbation leads to a significant alteration in FAM83A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FAM83A expression. Decide whether this perturbation leads to a significant alteration in FAM83A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of NKG7. Does perturbing UBASH3B lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of NKG7. Does perturbing UBASH3B lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4479,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ICAM4 expression is quantified. Does this perturbation result in a significant change in ICAM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ICAM4 expression is quantified. Does this perturbation result in a significant change in ICAM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is quantified. Does this perturbation result in a significant change in RP11-714G18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is quantified. Does this perturbation result in a significant change in RP11-714G18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1148,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 705,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in TAS1R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in TAS1R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-505P4.7 expression is measured. Determine whether RP11-505P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-505P4.7 expression is measured. Determine whether RP11-505P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2742,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3048,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HCN1 expression. Decide whether this perturbation leads to a significant alteration in HCN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HCN1 expression. Decide whether this perturbation leads to a significant alteration in HCN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1720,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5259,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is measured. Determine whether UCKL1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is measured. Determine whether UCKL1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2410,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Does this perturbation cause a significant change in TEX30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Does this perturbation cause a significant change in TEX30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4130,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Does this perturbation cause a significant change in ITGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Does this perturbation cause a significant change in ITGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in DLX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in DLX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ADD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ADD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of COL18A1-AS1. Does this perturbation cause a significant change in COL18A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of COL18A1-AS1. Does this perturbation cause a significant change in COL18A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3408,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor RP11-1085N6.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-1085N6.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor RP11-1085N6.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-1085N6.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2039,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is measured. Determine whether RP11-290L1.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is measured. Determine whether RP11-290L1.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of LPAR2. Does this perturbation cause a significant change in LPAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of LPAR2. Does this perturbation cause a significant change in LPAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2344,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of RASGRF2. Does perturbing MIDN lead to a significant change in RASGRF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of RASGRF2. Does perturbing MIDN lead to a significant change in RASGRF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and HBG1 expression is quantified. Does this perturbation result in a significant change in HBG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and HBG1 expression is quantified. Does this perturbation result in a significant change in HBG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in SLCO6A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in SLCO6A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 10,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Does this perturbation cause a significant change in CLU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Does this perturbation cause a significant change in CLU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in AC007193.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in AC007193.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and LRRC36 expression is quantified. Does this perturbation result in a significant change in LRRC36 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and LRRC36 expression is quantified. Does this perturbation result in a significant change in LRRC36 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5323,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ATF6B expression is observed. Does this perturbation lead to a significant difference in ATF6B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ATF6B expression is observed. Does this perturbation lead to a significant difference in ATF6B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is measured. Determine whether RP11-286H15.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is measured. Determine whether RP11-286H15.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ATP8B4 expression is quantified. Does this perturbation result in a significant change in ATP8B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ATP8B4 expression is quantified. Does this perturbation result in a significant change in ATP8B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 260,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Does this perturbation cause a significant change in VGF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Does this perturbation cause a significant change in VGF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6068,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor CEBPD expression. Decide whether this perturbation leads to a significant alteration in CEBPD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor CEBPD expression. Decide whether this perturbation leads to a significant alteration in CEBPD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 953,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and TRGVA expression is observed. Does this perturbation lead to a significant difference in TRGVA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and TRGVA expression is observed. Does this perturbation lead to a significant difference in TRGVA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is measured. Determine whether SIGLEC15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is measured. Determine whether SIGLEC15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Determine whether HIST1H4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Determine whether HIST1H4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 87,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of RP11-1085N6.3. Does perturbing SAMD1 lead to a significant change in RP11-1085N6.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of RP11-1085N6.3. Does perturbing SAMD1 lead to a significant change in RP11-1085N6.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and APOL6 expression is measured. Determine whether APOL6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and APOL6 expression is measured. Determine whether APOL6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4718,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RP5-1142A6.2 expression. Decide whether this perturbation leads to a significant alteration in RP5-1142A6.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RP5-1142A6.2 expression. Decide whether this perturbation leads to a significant alteration in RP5-1142A6.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5448,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ANXA2R. Does perturbing HOXA13 lead to a significant change in ANXA2R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ANXA2R. Does perturbing HOXA13 lead to a significant change in ANXA2R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3656,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1983,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SNCG expression is observed. Does this perturbation lead to a significant difference in SNCG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SNCG expression is observed. Does this perturbation lead to a significant difference in SNCG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2178,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor PXK expression. Decide whether this perturbation leads to a significant alteration in PXK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor PXK expression. Decide whether this perturbation leads to a significant alteration in PXK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5248,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor RP11-662J14.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-662J14.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor RP11-662J14.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-662J14.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4457,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RHOH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RHOH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5700,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 426,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2393,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CTD-3126B10.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3126B10.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CTD-3126B10.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3126B10.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of CTC-490E21.10. Does perturbing KLF1 lead to a significant change in CTC-490E21.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of CTC-490E21.10. Does perturbing KLF1 lead to a significant change in CTC-490E21.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5698,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor SLC38A2 expression. Decide whether this perturbation leads to a significant alteration in SLC38A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor SLC38A2 expression. Decide whether this perturbation leads to a significant alteration in SLC38A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5029,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Determine whether DDX58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Determine whether DDX58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2555,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-505P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-505P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1798,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-128B16.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-128B16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-128B16.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-128B16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3602,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in RP11-452C8.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in RP11-452C8.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and CAPG expression is quantified. Does this perturbation result in a significant change in CAPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and CAPG expression is quantified. Does this perturbation result in a significant change in CAPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Determine whether ZIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Determine whether ZIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2776,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Determine whether ACSL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Determine whether ACSL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ZNF677. Does this perturbation cause a significant change in ZNF677 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ZNF677. Does this perturbation cause a significant change in ZNF677 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SNCG. Does this perturbation cause a significant change in SNCG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SNCG. Does this perturbation cause a significant change in SNCG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Determine whether CRAT37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Determine whether CRAT37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4680,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2325,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3108,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor LPAR2 expression. Decide whether this perturbation leads to a significant alteration in LPAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor LPAR2 expression. Decide whether this perturbation leads to a significant alteration in LPAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4376,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Determine whether MS4A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Determine whether MS4A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2998,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor FZD6 expression. Decide whether this perturbation leads to a significant alteration in FZD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor FZD6 expression. Decide whether this perturbation leads to a significant alteration in FZD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2637,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of AC007193.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of AC007193.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4836,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Determine whether NCALD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Determine whether NCALD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4800,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3398,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor CTB-49A3.5 expression. Decide whether this perturbation leads to a significant alteration in CTB-49A3.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor CTB-49A3.5 expression. Decide whether this perturbation leads to a significant alteration in CTB-49A3.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2329,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNX1. Does perturbing FOSB lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNX1. Does perturbing FOSB lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3453,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and TRPM2 expression is measured. Determine whether TRPM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and TRPM2 expression is measured. Determine whether TRPM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 854,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1233,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and MYLIP expression is observed. Does this perturbation lead to a significant difference in MYLIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and MYLIP expression is observed. Does this perturbation lead to a significant difference in MYLIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in XX-FW83563B9.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in XX-FW83563B9.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3319,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LRP10 expression is measured. Determine whether LRP10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LRP10 expression is measured. Determine whether LRP10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and AC007556.3 expression is quantified. Does this perturbation result in a significant change in AC007556.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and AC007556.3 expression is quantified. Does this perturbation result in a significant change in AC007556.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3663,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6083,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and SLC4A3 expression is observed. Does this perturbation lead to a significant difference in SLC4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and SLC4A3 expression is observed. Does this perturbation lead to a significant difference in SLC4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3513,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and MCC expression is observed. Does this perturbation lead to a significant difference in MCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and MCC expression is observed. Does this perturbation lead to a significant difference in MCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6026,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Determine whether IFIT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Determine whether IFIT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2475,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in SOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in SOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of TLCD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of TLCD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4377,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and MT1E expression is quantified. Does this perturbation result in a significant change in MT1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and MT1E expression is quantified. Does this perturbation result in a significant change in MT1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 413,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and LINC00479 expression is observed. Does this perturbation lead to a significant difference in LINC00479 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and LINC00479 expression is observed. Does this perturbation lead to a significant difference in LINC00479 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2193,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and IL1RN expression is observed. Does this perturbation lead to a significant difference in IL1RN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and IL1RN expression is observed. Does this perturbation lead to a significant difference in IL1RN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and FNDC3A expression is measured. Determine whether FNDC3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and FNDC3A expression is measured. Determine whether FNDC3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1057,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of AGXT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of AGXT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6216,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Determine whether RP11-109E24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Determine whether RP11-109E24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5454,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RUNX1. Does perturbing ARID1A lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RUNX1. Does perturbing ARID1A lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1748,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3417,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of TPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of TPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6253,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and TRAPPC3L expression is observed. Does this perturbation lead to a significant difference in TRAPPC3L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and TRAPPC3L expression is observed. Does this perturbation lead to a significant difference in TRAPPC3L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 493,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of RSPO4. Does perturbing FOXL2 lead to a significant change in RSPO4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of RSPO4. Does perturbing FOXL2 lead to a significant change in RSPO4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 128,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ADGRF1 expression is quantified. Does this perturbation result in a significant change in ADGRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ADGRF1 expression is quantified. Does this perturbation result in a significant change in ADGRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4362,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is quantified. Does this perturbation result in a significant change in TFAP2A-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is quantified. Does this perturbation result in a significant change in TFAP2A-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PTRF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PTRF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6190,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Does this perturbation cause a significant change in CRAT37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Does this perturbation cause a significant change in CRAT37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2570,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Does this perturbation cause a significant change in RP11-328J14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Does this perturbation cause a significant change in RP11-328J14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6119,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1527,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5164,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3040,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Does this perturbation cause a significant change in HCN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Does this perturbation cause a significant change in HCN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3349,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is measured. Determine whether RP11-76E17.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is measured. Determine whether RP11-76E17.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2547,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2202,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and LINC01342 expression is quantified. Does this perturbation result in a significant change in LINC01342 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and LINC01342 expression is quantified. Does this perturbation result in a significant change in LINC01342 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1731,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of RP11-195C7.1. Does perturbing HES7 lead to a significant change in RP11-195C7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of RP11-195C7.1. Does perturbing HES7 lead to a significant change in RP11-195C7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2313,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2373,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CD59 expression is observed. Does this perturbation lead to a significant difference in CD59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CD59 expression is observed. Does this perturbation lead to a significant difference in CD59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of PTPRS. Does perturbing FEV lead to a significant change in PTPRS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of PTPRS. Does perturbing FEV lead to a significant change in PTPRS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3903,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and TNFRSF12A expression is observed. Does this perturbation lead to a significant difference in TNFRSF12A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and TNFRSF12A expression is observed. Does this perturbation lead to a significant difference in TNFRSF12A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and FMNL1 expression is measured. Determine whether FMNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and FMNL1 expression is measured. Determine whether FMNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5313,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and EWSAT1 expression is observed. Does this perturbation lead to a significant difference in EWSAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and EWSAT1 expression is observed. Does this perturbation lead to a significant difference in EWSAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in LINC01003 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in LINC01003 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of FCGR3A. Does perturbing ZBTB10 lead to a significant change in FCGR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of FCGR3A. Does perturbing ZBTB10 lead to a significant change in FCGR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 514,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ZNF85. Does this perturbation cause a significant change in ZNF85 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ZNF85. Does this perturbation cause a significant change in ZNF85 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 328,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1658,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 957,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of TRGVA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of TRGVA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and HBE1 expression is measured. Determine whether HBE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and HBE1 expression is measured. Determine whether HBE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Determine whether SERPINF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Determine whether SERPINF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4107,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of TOX. Does this perturbation cause a significant change in TOX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of TOX. Does this perturbation cause a significant change in TOX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RP3-467K16.2. Does perturbing SLC6A9 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RP3-467K16.2. Does perturbing SLC6A9 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 295,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in RP4-565E6.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in RP4-565E6.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and FCGR3A expression is measured. Determine whether FCGR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and FCGR3A expression is measured. Determine whether FCGR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CCS expression is quantified. Does this perturbation result in a significant change in CCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CCS expression is quantified. Does this perturbation result in a significant change in CCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6160,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Does this perturbation cause a significant change in DLX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Does this perturbation cause a significant change in DLX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1840,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Does this perturbation cause a significant change in AC004051.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Does this perturbation cause a significant change in AC004051.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2700,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3024,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of MYC. Does this perturbation cause a significant change in MYC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of MYC. Does this perturbation cause a significant change in MYC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6173,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SLC2A3 expression is quantified. Does this perturbation result in a significant change in SLC2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SLC2A3 expression is quantified. Does this perturbation result in a significant change in SLC2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-567N4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-567N4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3593,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and TUBB3 expression is observed. Does this perturbation lead to a significant difference in TUBB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and TUBB3 expression is observed. Does this perturbation lead to a significant difference in TUBB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of MMP19. Does perturbing TBX3 lead to a significant change in MMP19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of MMP19. Does perturbing TBX3 lead to a significant change in MMP19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of H1FNT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of H1FNT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2282,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 674,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 501,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of CTNNB1. Does perturbing GLB1L2 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of CTNNB1. Does perturbing GLB1L2 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is quantified. Does this perturbation result in a significant change in RP11-180M15.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is quantified. Does this perturbation result in a significant change in RP11-180M15.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CPXM1 expression is quantified. Does this perturbation result in a significant change in CPXM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CPXM1 expression is quantified. Does this perturbation result in a significant change in CPXM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5218,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CTD-2012K14.6 expression. Decide whether this perturbation leads to a significant alteration in CTD-2012K14.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CTD-2012K14.6 expression. Decide whether this perturbation leads to a significant alteration in CTD-2012K14.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2336,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Determine whether C1orf141 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Determine whether C1orf141 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 728,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and RETN expression is measured. Determine whether RETN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and RETN expression is measured. Determine whether RETN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 840,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Does this perturbation cause a significant change in ARPC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Does this perturbation cause a significant change in ARPC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3556,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TUBA1A. Does perturbing MAP7D1 lead to a significant change in TUBA1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TUBA1A. Does perturbing MAP7D1 lead to a significant change in TUBA1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4880,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4165,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4390,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Does this perturbation cause a significant change in AK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Does this perturbation cause a significant change in AK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5690,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Does this perturbation cause a significant change in SLC38A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Does this perturbation cause a significant change in SLC38A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of FCGR2A. Does perturbing KLF1 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of FCGR2A. Does perturbing KLF1 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ZMAT3. Does perturbing SPI1 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ZMAT3. Does perturbing SPI1 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5803,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and DPYSL2 expression is observed. Does this perturbation lead to a significant difference in DPYSL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and DPYSL2 expression is observed. Does this perturbation lead to a significant difference in DPYSL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 123,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3407,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of RP11-1085N6.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of RP11-1085N6.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2578,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-328J14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-328J14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Determine whether ASIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Determine whether ASIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3210,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Determine whether TUBB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Determine whether TUBB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of PSMB8. Does perturbing MAML2 lead to a significant change in PSMB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of PSMB8. Does perturbing MAML2 lead to a significant change in PSMB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4305,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in SLC22A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in SLC22A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6130,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5904,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of STRC. Does this perturbation cause a significant change in STRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of STRC. Does this perturbation cause a significant change in STRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCM2L expression is measured. Determine whether CCM2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCM2L expression is measured. Determine whether CCM2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 47,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP11-445O3.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP11-445O3.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3009,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of TLCD2. Does perturbing JUN lead to a significant change in TLCD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of TLCD2. Does perturbing JUN lead to a significant change in TLCD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4470,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 60,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5008,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor RLN3 expression. Decide whether this perturbation leads to a significant alteration in RLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor RLN3 expression. Decide whether this perturbation leads to a significant alteration in RLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5680,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3310,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Does this perturbation cause a significant change in LRP10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Does this perturbation cause a significant change in LRP10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1137,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of RP11-505P4.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of RP11-505P4.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 543,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2432,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ZNF610 expression is quantified. Does this perturbation result in a significant change in ZNF610 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ZNF610 expression is quantified. Does this perturbation result in a significant change in ZNF610 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Determine whether PKIG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Determine whether PKIG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of PCDHGA3. Does perturbing IER5L lead to a significant change in PCDHGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of PCDHGA3. Does perturbing IER5L lead to a significant change in PCDHGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6118,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2618,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ZIC4 expression. Decide whether this perturbation leads to a significant alteration in ZIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ZIC4 expression. Decide whether this perturbation leads to a significant alteration in ZIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4847,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of C19orf38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of C19orf38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5056,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2130,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Does this perturbation cause a significant change in CCDC148 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Does this perturbation cause a significant change in CCDC148 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4516,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Determine whether TPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Determine whether TPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and CCNJL expression is measured. Determine whether CCNJL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and CCNJL expression is measured. Determine whether CCNJL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C6orf1. Does perturbing RHOXF2BB lead to a significant change in C6orf1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C6orf1. Does perturbing RHOXF2BB lead to a significant change in C6orf1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2954,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3664,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 752,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLA2G1B expression is quantified. Does this perturbation result in a significant change in PLA2G1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLA2G1B expression is quantified. Does this perturbation result in a significant change in PLA2G1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3522,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ATP8A1 expression is quantified. Does this perturbation result in a significant change in ATP8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ATP8A1 expression is quantified. Does this perturbation result in a significant change in ATP8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is quantified. Does this perturbation result in a significant change in RP11-320G24.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is quantified. Does this perturbation result in a significant change in RP11-320G24.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4693,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2394,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CTD-3126B10.4. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CTD-3126B10.4. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3888,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor KRT79 expression. Decide whether this perturbation leads to a significant alteration in KRT79 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor KRT79 expression. Decide whether this perturbation leads to a significant alteration in KRT79 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5841,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LRRTM4. Does perturbing SNAI1 lead to a significant change in LRRTM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LRRTM4. Does perturbing SNAI1 lead to a significant change in LRRTM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3427,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of APOL6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of APOL6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3193,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of RP11-286H15.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of RP11-286H15.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SPANXN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SPANXN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5077,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of LINC01338 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of LINC01338 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of TFRC. Does perturbing COL2A1 lead to a significant change in TFRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of TFRC. Does perturbing COL2A1 lead to a significant change in TFRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C6orf1 expression is quantified. Does this perturbation result in a significant change in C6orf1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C6orf1 expression is quantified. Does this perturbation result in a significant change in C6orf1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of EMP3. Does perturbing IKZF3 lead to a significant change in EMP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of EMP3. Does perturbing IKZF3 lead to a significant change in EMP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP11-345P4.7. Does this perturbation cause a significant change in RP11-345P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP11-345P4.7. Does this perturbation cause a significant change in RP11-345P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1783,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-567N4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-567N4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-567N4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-567N4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4243,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and SEMA3B expression is observed. Does this perturbation lead to a significant difference in SEMA3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and SEMA3B expression is observed. Does this perturbation lead to a significant difference in SEMA3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5970,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Does this perturbation cause a significant change in HMOX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Does this perturbation cause a significant change in HMOX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3662,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4798,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PAMR1 expression. Decide whether this perturbation leads to a significant alteration in PAMR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PAMR1 expression. Decide whether this perturbation leads to a significant alteration in PAMR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4853,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 330,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Does this perturbation cause a significant change in LRRC36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Does this perturbation cause a significant change in LRRC36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 863,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CYP3A5 expression is observed. Does this perturbation lead to a significant difference in CYP3A5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CYP3A5 expression is observed. Does this perturbation lead to a significant difference in CYP3A5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1910,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Does this perturbation cause a significant change in S100A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Does this perturbation cause a significant change in S100A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3873,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4463,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3696,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Determine whether RP11-514P8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Determine whether RP11-514P8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2724,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 908,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1453,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5194,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of HCAR2. Does this perturbation cause a significant change in HCAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of HCAR2. Does this perturbation cause a significant change in HCAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4300,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Does this perturbation cause a significant change in SLC22A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Does this perturbation cause a significant change in SLC22A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of KRT79. Does perturbing C3orf72 lead to a significant change in KRT79 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of KRT79. Does perturbing C3orf72 lead to a significant change in KRT79 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Determine whether PLA2G1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Determine whether PLA2G1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 439,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5913,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and LEFTY1 expression is observed. Does this perturbation lead to a significant difference in LEFTY1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and LEFTY1 expression is observed. Does this perturbation lead to a significant difference in LEFTY1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4918,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RIT1 expression. Decide whether this perturbation leads to a significant alteration in RIT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RIT1 expression. Decide whether this perturbation leads to a significant alteration in RIT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5093,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and PLEK expression is observed. Does this perturbation lead to a significant difference in PLEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and PLEK expression is observed. Does this perturbation lead to a significant difference in PLEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Determine whether DRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Determine whether DRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5824,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3055,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in GPR157 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in GPR157 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and DDX58 expression is measured. Determine whether DDX58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and DDX58 expression is measured. Determine whether DDX58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 28,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of C10orf11. Does perturbing COL1A1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of C10orf11. Does perturbing COL1A1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5173,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and APOBR expression is observed. Does this perturbation lead to a significant difference in APOBR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and APOBR expression is observed. Does this perturbation lead to a significant difference in APOBR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2950,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2949,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of FABP5. Does perturbing HOXB9 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of FABP5. Does perturbing HOXB9 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Determine whether RP11-128B16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Determine whether RP11-128B16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of PCK1. Does this perturbation cause a significant change in PCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of PCK1. Does this perturbation cause a significant change in PCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of DDX58. Does perturbing DUSP9 lead to a significant change in DDX58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of DDX58. Does perturbing DUSP9 lead to a significant change in DDX58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5047,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01420 expression is quantified. Does this perturbation result in a significant change in LINC01420 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01420 expression is quantified. Does this perturbation result in a significant change in LINC01420 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 813,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and HOXB6 expression is observed. Does this perturbation lead to a significant difference in HOXB6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and HOXB6 expression is observed. Does this perturbation lead to a significant difference in HOXB6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3710,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1923,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1805,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 856,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2288,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Determine whether FAM46C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Determine whether FAM46C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1358,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor GCM2 expression. Decide whether this perturbation leads to a significant alteration in GCM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor GCM2 expression. Decide whether this perturbation leads to a significant alteration in GCM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is measured. Determine whether RHOXF2BB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is measured. Determine whether RHOXF2BB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 720,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1370,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Does this perturbation cause a significant change in RP11-635N19.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Does this perturbation cause a significant change in RP11-635N19.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5214,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CTD-2012K14.6. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CTD-2012K14.6. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and EGOT expression is measured. Determine whether EGOT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and EGOT expression is measured. Determine whether EGOT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Determine whether CENPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Determine whether CENPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of HSD17B4. Does perturbing CEBPE lead to a significant change in HSD17B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of HSD17B4. Does perturbing CEBPE lead to a significant change in HSD17B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in COL21A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in COL21A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3314,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LRP10. Does this perturbation cause a significant change in LRP10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LRP10. Does this perturbation cause a significant change in LRP10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5346,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Determine whether TOR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Determine whether TOR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of DCAF13. Does perturbing ZBTB1 lead to a significant change in DCAF13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of DCAF13. Does perturbing ZBTB1 lead to a significant change in DCAF13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4197,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of SPANXD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of SPANXD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3023,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and MYC expression is observed. Does this perturbation lead to a significant difference in MYC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and MYC expression is observed. Does this perturbation lead to a significant difference in MYC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of NBR1. Does perturbing HNF4A lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of NBR1. Does perturbing HNF4A lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 200,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Does this perturbation cause a significant change in PKIG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Does this perturbation cause a significant change in PKIG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3215,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6003,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and TACC1 expression is observed. Does this perturbation lead to a significant difference in TACC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and TACC1 expression is observed. Does this perturbation lead to a significant difference in TACC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1944,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ORAI3. Does this perturbation cause a significant change in ORAI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ORAI3. Does this perturbation cause a significant change in ORAI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of CCNJL. Does perturbing SPI1 lead to a significant change in CCNJL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of CCNJL. Does perturbing SPI1 lead to a significant change in CCNJL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2098,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ABCA13 expression. Decide whether this perturbation leads to a significant alteration in ABCA13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ABCA13 expression. Decide whether this perturbation leads to a significant alteration in ABCA13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PAMR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PAMR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of MKNK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of MKNK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1090,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 315,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in GRAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in GRAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2973,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and TCAF2 expression is observed. Does this perturbation lead to a significant difference in TCAF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and TCAF2 expression is observed. Does this perturbation lead to a significant difference in TCAF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4443,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4543,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6243,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in TOX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in TOX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6032,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and PGA4 expression is quantified. Does this perturbation result in a significant change in PGA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and PGA4 expression is quantified. Does this perturbation result in a significant change in PGA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CITED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CITED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01358 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01358 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1886,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Determine whether MTURN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Determine whether MTURN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2600,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3621,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of GYPE. Does perturbing PRTG lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of GYPE. Does perturbing PRTG lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AC034228.4 expression is measured. Determine whether AC034228.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AC034228.4 expression is measured. Determine whether AC034228.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of TFAP2A. Does perturbing MAP4K3 lead to a significant change in TFAP2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of TFAP2A. Does perturbing MAP4K3 lead to a significant change in TFAP2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4661,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of RP11-442O1.4. Does perturbing CSRNP1 lead to a significant change in RP11-442O1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of RP11-442O1.4. Does perturbing CSRNP1 lead to a significant change in RP11-442O1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5528,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor SPARC expression. Decide whether this perturbation leads to a significant alteration in SPARC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor SPARC expression. Decide whether this perturbation leads to a significant alteration in SPARC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Determine whether STRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Determine whether STRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and DRC1 expression is measured. Determine whether DRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and DRC1 expression is measured. Determine whether DRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-567N4.3 expression is measured. Determine whether RP11-567N4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-567N4.3 expression is measured. Determine whether RP11-567N4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and AC004051.2 expression is measured. Determine whether AC004051.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and AC004051.2 expression is measured. Determine whether AC004051.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of AC016629.3. Does perturbing PRTG lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of AC016629.3. Does perturbing PRTG lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1600,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Does this perturbation cause a significant change in RPS6KA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Does this perturbation cause a significant change in RPS6KA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and SPANXD expression is measured. Determine whether SPANXD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and SPANXD expression is measured. Determine whether SPANXD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of S100A3. Does this perturbation cause a significant change in S100A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of S100A3. Does this perturbation cause a significant change in S100A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4708,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor CNN2 expression. Decide whether this perturbation leads to a significant alteration in CNN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor CNN2 expression. Decide whether this perturbation leads to a significant alteration in CNN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2250,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Does this perturbation cause a significant change in INADL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Does this perturbation cause a significant change in INADL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM118A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM118A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1419,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is quantified. Does this perturbation result in a significant change in COL18A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is quantified. Does this perturbation result in a significant change in COL18A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2321,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of IGDCC3. Does perturbing MAP4K3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of IGDCC3. Does perturbing MAP4K3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5414,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of SLC31A2. Does this perturbation cause a significant change in SLC31A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of SLC31A2. Does this perturbation cause a significant change in SLC31A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5182,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and TMEM88 expression is quantified. Does this perturbation result in a significant change in TMEM88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and TMEM88 expression is quantified. Does this perturbation result in a significant change in TMEM88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5278,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1290,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Does this perturbation cause a significant change in DSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Does this perturbation cause a significant change in DSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 872,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2230,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Does this perturbation cause a significant change in TAPBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Does this perturbation cause a significant change in TAPBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1360,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Does this perturbation cause a significant change in TOX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Does this perturbation cause a significant change in TOX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 361,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of MT1E. Does perturbing BCORL1 lead to a significant change in MT1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of MT1E. Does perturbing BCORL1 lead to a significant change in MT1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1918,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor S100A3 expression. Decide whether this perturbation leads to a significant alteration in S100A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor S100A3 expression. Decide whether this perturbation leads to a significant alteration in S100A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4988,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and DEK expression is measured. Determine whether DEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and DEK expression is measured. Determine whether DEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 990,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1911,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of S100A3. Does perturbing RHOXF2BB lead to a significant change in S100A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of S100A3. Does perturbing RHOXF2BB lead to a significant change in S100A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is measured. Determine whether RP11-442O1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is measured. Determine whether RP11-442O1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4857,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ABCA6. Does perturbing KIAA1804 lead to a significant change in ABCA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ABCA6. Does perturbing KIAA1804 lead to a significant change in ABCA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of BCL2L11. Does this perturbation cause a significant change in BCL2L11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of BCL2L11. Does this perturbation cause a significant change in BCL2L11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5535,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in MOGAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in MOGAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4955,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6071,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of RP11-38J22.3. Does perturbing HK2 lead to a significant change in RP11-38J22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of RP11-38J22.3. Does perturbing HK2 lead to a significant change in RP11-38J22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SDSL expression is quantified. Does this perturbation result in a significant change in SDSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SDSL expression is quantified. Does this perturbation result in a significant change in SDSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3690,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Does this perturbation cause a significant change in RP11-514P8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Does this perturbation cause a significant change in RP11-514P8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1103,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and PRTN3 expression is observed. Does this perturbation lead to a significant difference in PRTN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and PRTN3 expression is observed. Does this perturbation lead to a significant difference in PRTN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3117,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of AC145110.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of AC145110.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and NCALD expression is measured. Determine whether NCALD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and NCALD expression is measured. Determine whether NCALD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1786,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Determine whether RP11-567N4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Determine whether RP11-567N4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5813,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1015,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4704,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AC034228.4. Does perturbing HNF4A lead to a significant change in AC034228.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AC034228.4. Does perturbing HNF4A lead to a significant change in AC034228.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4297,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AC034228.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AC034228.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ESAM. Does perturbing ATL1 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ESAM. Does perturbing ATL1 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of CTB-49A3.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of CTB-49A3.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4403,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CDK1 expression is observed. Does this perturbation lead to a significant difference in CDK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CDK1 expression is observed. Does this perturbation lead to a significant difference in CDK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6062,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and CEBPD expression is quantified. Does this perturbation result in a significant change in CEBPD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and CEBPD expression is quantified. Does this perturbation result in a significant change in CEBPD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1682,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and LMNA expression is quantified. Does this perturbation result in a significant change in LMNA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and LMNA expression is quantified. Does this perturbation result in a significant change in LMNA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 647,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of CTA-384D8.34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of CTA-384D8.34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 269,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and VGF expression is measured. Determine whether VGF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and VGF expression is measured. Determine whether VGF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CRAT37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CRAT37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CTD-2378E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CTD-2378E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5966,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Determine whether RGPD5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Determine whether RGPD5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 927,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and SPANXD expression is quantified. Does this perturbation result in a significant change in SPANXD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and SPANXD expression is quantified. Does this perturbation result in a significant change in SPANXD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4383,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and PHACTR1 expression is observed. Does this perturbation lead to a significant difference in PHACTR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and PHACTR1 expression is observed. Does this perturbation lead to a significant difference in PHACTR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 441,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of HBE1. Does perturbing MEIS1 lead to a significant change in HBE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of HBE1. Does perturbing MEIS1 lead to a significant change in HBE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2692,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and RP11-91A18.4 expression is quantified. Does this perturbation result in a significant change in RP11-91A18.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and RP11-91A18.4 expression is quantified. Does this perturbation result in a significant change in RP11-91A18.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2354,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of SOX4. Does this perturbation cause a significant change in SOX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of SOX4. Does this perturbation cause a significant change in SOX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3839,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is measured. Determine whether RP3-510H16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is measured. Determine whether RP3-510H16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5843,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LRRTM4 expression is observed. Does this perturbation lead to a significant difference in LRRTM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LRRTM4 expression is observed. Does this perturbation lead to a significant difference in LRRTM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 6110,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6146,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Determine whether CCNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Determine whether CCNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1502,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and BMP2K expression is quantified. Does this perturbation result in a significant change in BMP2K expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and BMP2K expression is quantified. Does this perturbation result in a significant change in BMP2K expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 268,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor VGF expression. Decide whether this perturbation leads to a significant alteration in VGF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor VGF expression. Decide whether this perturbation leads to a significant alteration in VGF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of PSMB8. Does this perturbation cause a significant change in PSMB8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of PSMB8. Does this perturbation cause a significant change in PSMB8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3339,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and CST9L expression is measured. Determine whether CST9L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and CST9L expression is measured. Determine whether CST9L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1989,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SNCG expression is measured. Determine whether SNCG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SNCG expression is measured. Determine whether SNCG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LRRC74B expression is measured. Determine whether LRRC74B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LRRC74B expression is measured. Determine whether LRRC74B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3883,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and KRT79 expression is observed. Does this perturbation lead to a significant difference in KRT79 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and KRT79 expression is observed. Does this perturbation lead to a significant difference in KRT79 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MYOZ3. Does perturbing LYL1 lead to a significant change in MYOZ3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MYOZ3. Does perturbing LYL1 lead to a significant change in MYOZ3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RGPD5 expression is measured. Determine whether RGPD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RGPD5 expression is measured. Determine whether RGPD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1138,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor RP11-505P4.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor RP11-505P4.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3083,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AP1S2. Does perturbing HNF4A lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AP1S2. Does perturbing HNF4A lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and TUBB expression is quantified. Does this perturbation result in a significant change in TUBB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and TUBB expression is quantified. Does this perturbation result in a significant change in TUBB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5620,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Does this perturbation cause a significant change in FAM83A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Does this perturbation cause a significant change in FAM83A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4360,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4593,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 184,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of LGALS12. Does this perturbation cause a significant change in LGALS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of LGALS12. Does this perturbation cause a significant change in LGALS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of YPEL3. Does perturbing PTPN9 lead to a significant change in YPEL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of YPEL3. Does perturbing PTPN9 lead to a significant change in YPEL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and HMGA2 expression is measured. Determine whether HMGA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and HMGA2 expression is measured. Determine whether HMGA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and SPARC expression is measured. Determine whether SPARC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and SPARC expression is measured. Determine whether SPARC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of IER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of IER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5848,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LRRTM4 expression. Decide whether this perturbation leads to a significant alteration in LRRTM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LRRTM4 expression. Decide whether this perturbation leads to a significant alteration in LRRTM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5740,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5590,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Does this perturbation cause a significant change in LINC01395 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Does this perturbation cause a significant change in LINC01395 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3157,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1529,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of COTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of COTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2980,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and YPEL3 expression is measured. Determine whether YPEL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and YPEL3 expression is measured. Determine whether YPEL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4231,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CTB-161C1.1. Does perturbing CEBPA lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CTB-161C1.1. Does perturbing CEBPA lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2548,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-510J16.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-510J16.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 135,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2033,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and RP11-290L1.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290L1.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and RP11-290L1.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290L1.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5031,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of CCDC136. Does perturbing OSR2 lead to a significant change in CCDC136 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of CCDC136. Does perturbing OSR2 lead to a significant change in CCDC136 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4871,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of CAPG. Does perturbing NCL lead to a significant change in CAPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of CAPG. Does perturbing NCL lead to a significant change in CAPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 506,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1408,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and AIM1 expression is measured. Determine whether AIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and AIM1 expression is measured. Determine whether AIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3387,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HHEX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HHEX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2403,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SLC20A1 expression is observed. Does this perturbation lead to a significant difference in SLC20A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SLC20A1 expression is observed. Does this perturbation lead to a significant difference in SLC20A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Does this perturbation cause a significant change in RP11-646I6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Does this perturbation cause a significant change in RP11-646I6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of CCNJL. Does this perturbation cause a significant change in CCNJL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of CCNJL. Does this perturbation cause a significant change in CCNJL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1050,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Does this perturbation cause a significant change in AGXT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Does this perturbation cause a significant change in AGXT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Determine whether IGHEP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Determine whether IGHEP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1543,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and RASGRF2 expression is observed. Does this perturbation lead to a significant difference in RASGRF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and RASGRF2 expression is observed. Does this perturbation lead to a significant difference in RASGRF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1817,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1632,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and CEBPA expression is quantified. Does this perturbation result in a significant change in CEBPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and CEBPA expression is quantified. Does this perturbation result in a significant change in CEBPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 186,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Determine whether LGALS12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Determine whether LGALS12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5290,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Does this perturbation cause a significant change in KRTAP9-9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Does this perturbation cause a significant change in KRTAP9-9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of VMP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of VMP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of BMP2K. Does this perturbation cause a significant change in BMP2K expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of BMP2K. Does this perturbation cause a significant change in BMP2K expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1990,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1848,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor AC004051.2 expression. Decide whether this perturbation leads to a significant alteration in AC004051.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor AC004051.2 expression. Decide whether this perturbation leads to a significant alteration in AC004051.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3410,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Does this perturbation cause a significant change in TPH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Does this perturbation cause a significant change in TPH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3867,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of DNAJB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of DNAJB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CDK1. Does perturbing IGDCC3 lead to a significant change in CDK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CDK1. Does perturbing IGDCC3 lead to a significant change in CDK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5523,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and SPARC expression is observed. Does this perturbation lead to a significant difference in SPARC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and SPARC expression is observed. Does this perturbation lead to a significant difference in SPARC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CCS expression is measured. Determine whether CCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CCS expression is measured. Determine whether CCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CARMN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CARMN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5097,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of PLEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of PLEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C8orf22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C8orf22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4968,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LINC01562 expression is quantified. Does this perturbation result in a significant change in LINC01562 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LINC01562 expression is quantified. Does this perturbation result in a significant change in LINC01562 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4381,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of PHACTR1. Does perturbing IGDCC3 lead to a significant change in PHACTR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of PHACTR1. Does perturbing IGDCC3 lead to a significant change in PHACTR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Determine whether MACF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Determine whether MACF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4785,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in RP11-202A13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in RP11-202A13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4327,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 485,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RNF168. Does this perturbation cause a significant change in RNF168 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RNF168. Does this perturbation cause a significant change in RNF168 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of CAPG. Does this perturbation cause a significant change in CAPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of CAPG. Does this perturbation cause a significant change in CAPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1285,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in COTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in COTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-646I6.6. Does this perturbation cause a significant change in RP11-646I6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-646I6.6. Does this perturbation cause a significant change in RP11-646I6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1122,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is quantified. Does this perturbation result in a significant change in CTC-492K19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is quantified. Does this perturbation result in a significant change in CTC-492K19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1384,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in RP11-38J22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in RP11-38J22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5908,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor STRC expression. Decide whether this perturbation leads to a significant alteration in STRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor STRC expression. Decide whether this perturbation leads to a significant alteration in STRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3538,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor C1orf162 expression. Decide whether this perturbation leads to a significant alteration in C1orf162 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor C1orf162 expression. Decide whether this perturbation leads to a significant alteration in C1orf162 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2328,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3127,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of AIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of AIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Determine whether RSPO4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Determine whether RSPO4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1317,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LINC01562 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LINC01562 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2755,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CTD-3131K8.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CTD-3131K8.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ABCA13 expression is measured. Determine whether ABCA13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ABCA13 expression is measured. Determine whether ABCA13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4058,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor PROX1 expression. Decide whether this perturbation leads to a significant alteration in PROX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor PROX1 expression. Decide whether this perturbation leads to a significant alteration in PROX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2931,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ARL6IP1. Does perturbing C19orf26 lead to a significant change in ARL6IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ARL6IP1. Does perturbing C19orf26 lead to a significant change in ARL6IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1940,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Does this perturbation cause a significant change in ORAI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Does this perturbation cause a significant change in ORAI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in TACC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in TACC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4136,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Determine whether ITGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Determine whether ITGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PAMR1 expression is measured. Determine whether PAMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PAMR1 expression is measured. Determine whether PAMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1981,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SNCG. Does perturbing S1PR2 lead to a significant change in SNCG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SNCG. Does perturbing S1PR2 lead to a significant change in SNCG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2176,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Determine whether PXK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Determine whether PXK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5480,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Does this perturbation cause a significant change in PERM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Does this perturbation cause a significant change in PERM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6229,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CENPE expression is measured. Determine whether CENPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CENPE expression is measured. Determine whether CENPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3365,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in FAM19A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in FAM19A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5430,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Does this perturbation cause a significant change in LINC01227 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Does this perturbation cause a significant change in LINC01227 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4106,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5496,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Determine whether IGFL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Determine whether IGFL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5720,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Does this perturbation cause a significant change in ADGRF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Does this perturbation cause a significant change in ADGRF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5380,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Does this perturbation cause a significant change in HBG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Does this perturbation cause a significant change in HBG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2498,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor CHST15 expression. Decide whether this perturbation leads to a significant alteration in CHST15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor CHST15 expression. Decide whether this perturbation leads to a significant alteration in CHST15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1745,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5360,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Does this perturbation cause a significant change in CTSW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Does this perturbation cause a significant change in CTSW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5893,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and RP3-525N10.2 expression is observed. Does this perturbation lead to a significant difference in RP3-525N10.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and RP3-525N10.2 expression is observed. Does this perturbation lead to a significant difference in RP3-525N10.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and IL1RN expression is measured. Determine whether IL1RN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and IL1RN expression is measured. Determine whether IL1RN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5397,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CMB9-22P13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CMB9-22P13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6048,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor NPW expression. Decide whether this perturbation leads to a significant alteration in NPW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor NPW expression. Decide whether this perturbation leads to a significant alteration in NPW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in CTSS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in CTSS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1144,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4306,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Determine whether SLC22A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Determine whether SLC22A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4162,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1597,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of CALY indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of CALY indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of MOGAT2. Does perturbing JUN lead to a significant change in MOGAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of MOGAT2. Does perturbing JUN lead to a significant change in MOGAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 573,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and CTC-490E21.10 expression is observed. Does this perturbation lead to a significant difference in CTC-490E21.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and CTC-490E21.10 expression is observed. Does this perturbation lead to a significant difference in CTC-490E21.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ATF6B expression is quantified. Does this perturbation result in a significant change in ATF6B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ATF6B expression is quantified. Does this perturbation result in a significant change in ATF6B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and RABAC1 expression is quantified. Does this perturbation result in a significant change in RABAC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and RABAC1 expression is quantified. Does this perturbation result in a significant change in RABAC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD47 expression is measured. Determine whether CD47 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD47 expression is measured. Determine whether CD47 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2123,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 423,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1253,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-497G19.7 expression is observed. Does this perturbation lead to a significant difference in RP11-497G19.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-497G19.7 expression is observed. Does this perturbation lead to a significant difference in RP11-497G19.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2606,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 589,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ETS1 expression is measured. Determine whether ETS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ETS1 expression is measured. Determine whether ETS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 310,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Does this perturbation cause a significant change in GRAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Does this perturbation cause a significant change in GRAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5858,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor SCG5 expression. Decide whether this perturbation leads to a significant alteration in SCG5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor SCG5 expression. Decide whether this perturbation leads to a significant alteration in SCG5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 612,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CTD-2378E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CTD-2378E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5453,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1540,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Does this perturbation cause a significant change in RASGRF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Does this perturbation cause a significant change in RASGRF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1881,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of MTURN. Does perturbing RHOXF2BB lead to a significant change in MTURN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of MTURN. Does perturbing RHOXF2BB lead to a significant change in MTURN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4113,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and RSPO4 expression is observed. Does this perturbation lead to a significant difference in RSPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and RSPO4 expression is observed. Does this perturbation lead to a significant difference in RSPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2018,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor AC078941.1 expression. Decide whether this perturbation leads to a significant alteration in AC078941.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor AC078941.1 expression. Decide whether this perturbation leads to a significant alteration in AC078941.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5573,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4576,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5048,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1898,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C8orf22 expression. Decide whether this perturbation leads to a significant alteration in C8orf22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C8orf22 expression. Decide whether this perturbation leads to a significant alteration in C8orf22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 787,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD47 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD47 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1933,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2984,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6027,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of IFIT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of IFIT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2291,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AC007246.3. Does perturbing MAP4K3 lead to a significant change in AC007246.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AC007246.3. Does perturbing MAP4K3 lead to a significant change in AC007246.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2075,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CKS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CKS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3415,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in TPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in TPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2936,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and SCG5 expression is measured. Determine whether SCG5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and SCG5 expression is measured. Determine whether SCG5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is measured. Determine whether PCDHGA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is measured. Determine whether PCDHGA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1571,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TPP1. Does perturbing DLX2 lead to a significant change in TPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TPP1. Does perturbing DLX2 lead to a significant change in TPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3859,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CCNB1 expression is measured. Determine whether CCNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CCNB1 expression is measured. Determine whether CCNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4438,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor RP11-180M15.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-180M15.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor RP11-180M15.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-180M15.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5250,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Does this perturbation cause a significant change in UCKL1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Does this perturbation cause a significant change in UCKL1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CCDC159 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CCDC159 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2191,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of IL1RN. Does perturbing CELF2 lead to a significant change in IL1RN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of IL1RN. Does perturbing CELF2 lead to a significant change in IL1RN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5392,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is quantified. Does this perturbation result in a significant change in CMB9-22P13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is quantified. Does this perturbation result in a significant change in CMB9-22P13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3993,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and CLTA expression is observed. Does this perturbation lead to a significant difference in CLTA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and CLTA expression is observed. Does this perturbation lead to a significant difference in CLTA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of FAM46C. Does this perturbation cause a significant change in FAM46C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of FAM46C. Does this perturbation cause a significant change in FAM46C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01227 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01227 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5228,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CIB3 expression. Decide whether this perturbation leads to a significant alteration in CIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CIB3 expression. Decide whether this perturbation leads to a significant alteration in CIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 971,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of CST3. Does perturbing LHX1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of CST3. Does perturbing LHX1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3470,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Does this perturbation cause a significant change in AC139099.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Does this perturbation cause a significant change in AC139099.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4759,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 208,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor PKIG expression. Decide whether this perturbation leads to a significant alteration in PKIG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor PKIG expression. Decide whether this perturbation leads to a significant alteration in PKIG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3247,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CD37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CD37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 967,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6156,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Determine whether PLA2G16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Determine whether PLA2G16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5874,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ANXA2R. Does this perturbation cause a significant change in ANXA2R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ANXA2R. Does this perturbation cause a significant change in ANXA2R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5898,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor RP3-525N10.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-525N10.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor RP3-525N10.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-525N10.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-290K4.2. Does perturbing PLK4 lead to a significant change in RP11-290K4.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-290K4.2. Does perturbing PLK4 lead to a significant change in RP11-290K4.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3507,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is quantified. Does this perturbation result in a significant change in RP11-537H15.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is quantified. Does this perturbation result in a significant change in RP11-537H15.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4183,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and RP11-362K14.7 expression is observed. Does this perturbation lead to a significant difference in RP11-362K14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and RP11-362K14.7 expression is observed. Does this perturbation lead to a significant difference in RP11-362K14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of RP11-452C8.1. Does this perturbation cause a significant change in RP11-452C8.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of RP11-452C8.1. Does this perturbation cause a significant change in RP11-452C8.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3980,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Does this perturbation cause a significant change in AKAP13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Does this perturbation cause a significant change in AKAP13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Determine whether AMPH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Determine whether AMPH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5125,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in CCNJL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in CCNJL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP11-345P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP11-345P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of TUBB. Does this perturbation cause a significant change in TUBB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of TUBB. Does this perturbation cause a significant change in TUBB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of RP11-369K17.1. Does perturbing TGFBR2 lead to a significant change in RP11-369K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of RP11-369K17.1. Does perturbing TGFBR2 lead to a significant change in RP11-369K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of RP11-290L1.2. Does this perturbation cause a significant change in RP11-290L1.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of RP11-290L1.2. Does this perturbation cause a significant change in RP11-290L1.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5149,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and RABAC1 expression is measured. Determine whether RABAC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and RABAC1 expression is measured. Determine whether RABAC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1242,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is quantified. Does this perturbation result in a significant change in RP11-259K5.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is quantified. Does this perturbation result in a significant change in RP11-259K5.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and MACF1 expression is measured. Determine whether MACF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and MACF1 expression is measured. Determine whether MACF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1323,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and VCX3B expression is quantified. Does this perturbation result in a significant change in VCX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and VCX3B expression is quantified. Does this perturbation result in a significant change in VCX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CCNL1. Does perturbing KIF18B lead to a significant change in CCNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CCNL1. Does perturbing KIF18B lead to a significant change in CCNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of AC007193.6. Does this perturbation cause a significant change in AC007193.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of AC007193.6. Does this perturbation cause a significant change in AC007193.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1251,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-497G19.7. Does perturbing COL2A1 lead to a significant change in RP11-497G19.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-497G19.7. Does perturbing COL2A1 lead to a significant change in RP11-497G19.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3265,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in NUMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in NUMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4212,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4477,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5299,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and KRTAP9-9 expression is measured. Determine whether KRTAP9-9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and KRTAP9-9 expression is measured. Determine whether KRTAP9-9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6033,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and PGA4 expression is observed. Does this perturbation lead to a significant difference in PGA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and PGA4 expression is observed. Does this perturbation lead to a significant difference in PGA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4829,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5170,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Does this perturbation cause a significant change in APOBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Does this perturbation cause a significant change in APOBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4948,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor LEFTY2 expression. Decide whether this perturbation leads to a significant alteration in LEFTY2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor LEFTY2 expression. Decide whether this perturbation leads to a significant alteration in LEFTY2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2850,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Does this perturbation cause a significant change in ANXA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Does this perturbation cause a significant change in ANXA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 905,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3844,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5747,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ADGRF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ADGRF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of RP4-565E6.1. Does this perturbation cause a significant change in RP4-565E6.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of RP4-565E6.1. Does this perturbation cause a significant change in RP4-565E6.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6210,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Does this perturbation cause a significant change in RP11-109E24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Does this perturbation cause a significant change in RP11-109E24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4741,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ICAM4. Does perturbing CNNM4 lead to a significant change in ICAM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ICAM4. Does perturbing CNNM4 lead to a significant change in ICAM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3777,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of RP1-59D14.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of RP1-59D14.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1526,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3761,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of IL20. Does perturbing BPGM lead to a significant change in IL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of IL20. Does perturbing BPGM lead to a significant change in IL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1206,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Determine whether ACP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Determine whether ACP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 308,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6237,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 35,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in PDE1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in PDE1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3124,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of AIM1. Does this perturbation cause a significant change in AIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of AIM1. Does this perturbation cause a significant change in AIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3399,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is measured. Determine whether CTB-49A3.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is measured. Determine whether CTB-49A3.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLA2G16 expression is quantified. Does this perturbation result in a significant change in PLA2G16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLA2G16 expression is quantified. Does this perturbation result in a significant change in PLA2G16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1610,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in GCM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in GCM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3951,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of RNF182. Does perturbing LYL1 lead to a significant change in RNF182 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of RNF182. Does perturbing LYL1 lead to a significant change in RNF182 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4195,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in SPANXD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in SPANXD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and TMEM154 expression is quantified. Does this perturbation result in a significant change in TMEM154 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and TMEM154 expression is quantified. Does this perturbation result in a significant change in TMEM154 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6159,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLA2G16 expression is measured. Determine whether PLA2G16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLA2G16 expression is measured. Determine whether PLA2G16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2720,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2409,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SLC20A1 expression is measured. Determine whether SLC20A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SLC20A1 expression is measured. Determine whether SLC20A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4070,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Does this perturbation cause a significant change in RP11-452C8.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Does this perturbation cause a significant change in RP11-452C8.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4568,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 544,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4851,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of AC074289.1. Does perturbing UBASH3A lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of AC074289.1. Does perturbing UBASH3A lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3221,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIPK1-AS1. Does perturbing CKS1B lead to a significant change in HIPK1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIPK1-AS1. Does perturbing CKS1B lead to a significant change in HIPK1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5827,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5130,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 900,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of CST9L. Does this perturbation cause a significant change in CST9L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of CST9L. Does this perturbation cause a significant change in CST9L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5304,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PPFIA4. Does this perturbation cause a significant change in PPFIA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PPFIA4. Does this perturbation cause a significant change in PPFIA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ACTC1 expression is measured. Determine whether ACTC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ACTC1 expression is measured. Determine whether ACTC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3979,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ARMCX3 expression is measured. Determine whether ARMCX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ARMCX3 expression is measured. Determine whether ARMCX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in RP11-76E17.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in RP11-76E17.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4530,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Does this perturbation cause a significant change in RP11-244F12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Does this perturbation cause a significant change in RP11-244F12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1468,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of MAOB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of MAOB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4630,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and FLJ12825 expression is quantified. Does this perturbation result in a significant change in FLJ12825 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and FLJ12825 expression is quantified. Does this perturbation result in a significant change in FLJ12825 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1689,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and LMNA expression is measured. Determine whether LMNA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and LMNA expression is measured. Determine whether LMNA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1740,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3789,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of VGF. Does perturbing ELMSAN1 lead to a significant change in VGF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of VGF. Does perturbing ELMSAN1 lead to a significant change in VGF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and TUBB3 expression is measured. Determine whether TUBB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and TUBB3 expression is measured. Determine whether TUBB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1373,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and RP11-635N19.1 expression is observed. Does this perturbation lead to a significant difference in RP11-635N19.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and RP11-635N19.1 expression is observed. Does this perturbation lead to a significant difference in RP11-635N19.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2972,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and TCAF2 expression is quantified. Does this perturbation result in a significant change in TCAF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and TCAF2 expression is quantified. Does this perturbation result in a significant change in TCAF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3099,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ZNF677 expression is measured. Determine whether ZNF677 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ZNF677 expression is measured. Determine whether ZNF677 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1183,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4367,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TFAP2A-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TFAP2A-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1112,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and C1orf228 expression is quantified. Does this perturbation result in a significant change in C1orf228 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and C1orf228 expression is quantified. Does this perturbation result in a significant change in C1orf228 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TRIM31. Does perturbing MEIS1 lead to a significant change in TRIM31 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TRIM31. Does perturbing MEIS1 lead to a significant change in TRIM31 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2969,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of CISH. Does perturbing PTPN12 lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of CISH. Does perturbing PTPN12 lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2764,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of IER3. Does this perturbation cause a significant change in IER3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of IER3. Does this perturbation cause a significant change in IER3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4563,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1436,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Determine whether CTD-3037G24.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Determine whether CTD-3037G24.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3272,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CARMN expression is quantified. Does this perturbation result in a significant change in CARMN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CARMN expression is quantified. Does this perturbation result in a significant change in CARMN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4430,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Does this perturbation cause a significant change in RP11-180M15.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Does this perturbation cause a significant change in RP11-180M15.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3616,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 672,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5890,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Does this perturbation cause a significant change in RP3-525N10.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Does this perturbation cause a significant change in RP3-525N10.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5850,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Does this perturbation cause a significant change in SCG5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Does this perturbation cause a significant change in SCG5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4019,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is measured. Determine whether RP11-6D1.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is measured. Determine whether RP11-6D1.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 816,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Determine whether HOXB6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Determine whether HOXB6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3534,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of C1orf162. Does this perturbation cause a significant change in C1orf162 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of C1orf162. Does this perturbation cause a significant change in C1orf162 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3698,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-514P8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-514P8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-514P8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-514P8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3020,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Does this perturbation cause a significant change in MYC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Does this perturbation cause a significant change in MYC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1142,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-567N4.3 expression is quantified. Does this perturbation result in a significant change in RP11-567N4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-567N4.3 expression is quantified. Does this perturbation result in a significant change in RP11-567N4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and CSRNP1 expression is quantified. Does this perturbation result in a significant change in CSRNP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and CSRNP1 expression is quantified. Does this perturbation result in a significant change in CSRNP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 448,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor HBE1 expression. Decide whether this perturbation leads to a significant alteration in HBE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor HBE1 expression. Decide whether this perturbation leads to a significant alteration in HBE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 681,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of RAB5B. Does perturbing FEV lead to a significant change in RAB5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of RAB5B. Does perturbing FEV lead to a significant change in RAB5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CMB9-22P13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CMB9-22P13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TM6SF2. Does perturbing KMT2A lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TM6SF2. Does perturbing KMT2A lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 188,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor LGALS12 expression. Decide whether this perturbation leads to a significant alteration in LGALS12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor LGALS12 expression. Decide whether this perturbation leads to a significant alteration in LGALS12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1230,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Does this perturbation cause a significant change in MYLIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Does this perturbation cause a significant change in MYLIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 313,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and GRAP2 expression is observed. Does this perturbation lead to a significant difference in GRAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and GRAP2 expression is observed. Does this perturbation lead to a significant difference in GRAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1196,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Determine whether CTD-2616J11.16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Determine whether CTD-2616J11.16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4018,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor RP11-6D1.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-6D1.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor RP11-6D1.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-6D1.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2332,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and C1orf141 expression is quantified. Does this perturbation result in a significant change in C1orf141 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and C1orf141 expression is quantified. Does this perturbation result in a significant change in C1orf141 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2378,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CD59 expression. Decide whether this perturbation leads to a significant alteration in CD59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CD59 expression. Decide whether this perturbation leads to a significant alteration in CD59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1493,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and MAOB expression is observed. Does this perturbation lead to a significant difference in MAOB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and MAOB expression is observed. Does this perturbation lead to a significant difference in MAOB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5862,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and VMP1 expression is quantified. Does this perturbation result in a significant change in VMP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and VMP1 expression is quantified. Does this perturbation result in a significant change in VMP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 228,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor DDX58 expression. Decide whether this perturbation leads to a significant alteration in DDX58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor DDX58 expression. Decide whether this perturbation leads to a significant alteration in DDX58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4140,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Does this perturbation cause a significant change in TMEM154 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Does this perturbation cause a significant change in TMEM154 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3301,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of PHLDA2. Does perturbing FOXA3 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of PHLDA2. Does perturbing FOXA3 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3035,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in EMP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in EMP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of TYROBP. Does perturbing KLF1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of TYROBP. Does perturbing KLF1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1958,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and SSTR3 expression is quantified. Does this perturbation result in a significant change in SSTR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and SSTR3 expression is quantified. Does this perturbation result in a significant change in SSTR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 994,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5292,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and KRTAP9-9 expression is quantified. Does this perturbation result in a significant change in KRTAP9-9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and KRTAP9-9 expression is quantified. Does this perturbation result in a significant change in KRTAP9-9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 956,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Determine whether TRGVA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Determine whether TRGVA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5246,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Determine whether RP11-662J14.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Determine whether RP11-662J14.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4253,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CCDC159 expression is observed. Does this perturbation lead to a significant difference in CCDC159 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CCDC159 expression is observed. Does this perturbation lead to a significant difference in CCDC159 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2038,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor RP11-290L1.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290L1.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor RP11-290L1.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290L1.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 749,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 600,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Does this perturbation cause a significant change in RP11-445F12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Does this perturbation cause a significant change in RP11-445F12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 324,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2928,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Determine whether SLC4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Determine whether SLC4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2074,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CKS2. Does this perturbation cause a significant change in CKS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CKS2. Does this perturbation cause a significant change in CKS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3699,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is measured. Determine whether RP11-514P8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is measured. Determine whether RP11-514P8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4187,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of RP11-362K14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of RP11-362K14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1508,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor BMP2K expression. Decide whether this perturbation leads to a significant alteration in BMP2K expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor BMP2K expression. Decide whether this perturbation leads to a significant alteration in BMP2K expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of MME indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of MME indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CYP2C18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CYP2C18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and TFRC expression is quantified. Does this perturbation result in a significant change in TFRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and TFRC expression is quantified. Does this perturbation result in a significant change in TFRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3459,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ATP8B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ATP8B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3598,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor TUBB3 expression. Decide whether this perturbation leads to a significant alteration in TUBB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor TUBB3 expression. Decide whether this perturbation leads to a significant alteration in TUBB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2458,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor RETN expression. Decide whether this perturbation leads to a significant alteration in RETN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor RETN expression. Decide whether this perturbation leads to a significant alteration in RETN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FAM83A expression is quantified. Does this perturbation result in a significant change in FAM83A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FAM83A expression is quantified. Does this perturbation result in a significant change in FAM83A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6115,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 734,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLAUR. Does this perturbation cause a significant change in PLAUR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLAUR. Does this perturbation cause a significant change in PLAUR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3615,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of TMEM154. Does perturbing KIAA1804 lead to a significant change in TMEM154 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of TMEM154. Does perturbing KIAA1804 lead to a significant change in TMEM154 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 340,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5470,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Does this perturbation cause a significant change in RP11-369K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Does this perturbation cause a significant change in RP11-369K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of GYPE. Does perturbing CNNM4 lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of GYPE. Does perturbing CNNM4 lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2659,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and MSRB1 expression is measured. Determine whether MSRB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and MSRB1 expression is measured. Determine whether MSRB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3313,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LRP10 expression is observed. Does this perturbation lead to a significant difference in LRP10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LRP10 expression is observed. Does this perturbation lead to a significant difference in LRP10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5067,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RP11-320G24.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RP11-320G24.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4411,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CTD-2527I21.14. Does perturbing IGDCC3 lead to a significant change in CTD-2527I21.14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CTD-2527I21.14. Does perturbing IGDCC3 lead to a significant change in CTD-2527I21.14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3985,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in AKAP13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in AKAP13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3897,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of HMGA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of HMGA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3293,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and XX-FW83563B9.5 expression is observed. Does this perturbation lead to a significant difference in XX-FW83563B9.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and XX-FW83563B9.5 expression is observed. Does this perturbation lead to a significant difference in XX-FW83563B9.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1604,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of RPS6KA2. Does this perturbation cause a significant change in RPS6KA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of RPS6KA2. Does this perturbation cause a significant change in RPS6KA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3170,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Does this perturbation cause a significant change in SSTR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Does this perturbation cause a significant change in SSTR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1200,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Does this perturbation cause a significant change in ACP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Does this perturbation cause a significant change in ACP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2497,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of CHST15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of CHST15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3559,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2921,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ATP10D. Does perturbing C19orf26 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ATP10D. Does perturbing C19orf26 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 140,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Does this perturbation cause a significant change in HSD17B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Does this perturbation cause a significant change in HSD17B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of FILIP1L. Does perturbing MAP2K3 lead to a significant change in FILIP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of FILIP1L. Does perturbing MAP2K3 lead to a significant change in FILIP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4673,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 163,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and RBM5-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and RBM5-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3716,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of GIPC2. Does perturbing HOXC13 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of GIPC2. Does perturbing HOXC13 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3691,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-514P8.2. Does perturbing PLK4 lead to a significant change in RP11-514P8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-514P8.2. Does perturbing PLK4 lead to a significant change in RP11-514P8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Determine whether RP4-565E6.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Determine whether RP4-565E6.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4848,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor C19orf38 expression. Decide whether this perturbation leads to a significant alteration in C19orf38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor C19orf38 expression. Decide whether this perturbation leads to a significant alteration in C19orf38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ORAI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ORAI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2309,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3422,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and APOL6 expression is quantified. Does this perturbation result in a significant change in APOL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and APOL6 expression is quantified. Does this perturbation result in a significant change in APOL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2649,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and TUBB expression is measured. Determine whether TUBB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and TUBB expression is measured. Determine whether TUBB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of FLJ12825. Does this perturbation cause a significant change in FLJ12825 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of FLJ12825. Does this perturbation cause a significant change in FLJ12825 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1987,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SNCG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SNCG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 428,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1573,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TPP1 expression is observed. Does this perturbation lead to a significant difference in TPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TPP1 expression is observed. Does this perturbation lead to a significant difference in TPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2660,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Does this perturbation cause a significant change in FAM118A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Does this perturbation cause a significant change in FAM118A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in RP11-355B11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in RP11-355B11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2770,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Does this perturbation cause a significant change in ACSL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Does this perturbation cause a significant change in ACSL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5599,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01395 expression is measured. Determine whether LINC01395 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01395 expression is measured. Determine whether LINC01395 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5614,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01358. Does this perturbation cause a significant change in LINC01358 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01358. Does this perturbation cause a significant change in LINC01358 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5114,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of KCNQ1-AS1. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of KCNQ1-AS1. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP11-345P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP11-345P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3030,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2968,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6222,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CENPE expression is quantified. Does this perturbation result in a significant change in CENPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CENPE expression is quantified. Does this perturbation result in a significant change in CENPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of TNFAIP2. Does this perturbation cause a significant change in TNFAIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of TNFAIP2. Does this perturbation cause a significant change in TNFAIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-259K5.1. Does this perturbation cause a significant change in RP11-259K5.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-259K5.1. Does this perturbation cause a significant change in RP11-259K5.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4746,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Determine whether ICAM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Determine whether ICAM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6139,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4469,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 997,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 6061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of CEBPD. Does perturbing HK2 lead to a significant change in CEBPD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of CEBPD. Does perturbing HK2 lead to a significant change in CEBPD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2379,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CD59 expression is measured. Determine whether CD59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CD59 expression is measured. Determine whether CD59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6261,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of MME. Does perturbing CDKN1C lead to a significant change in MME expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of MME. Does perturbing CDKN1C lead to a significant change in MME expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3818,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-563J2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-563J2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-563J2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-563J2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3038,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor EMP3 expression. Decide whether this perturbation leads to a significant alteration in EMP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor EMP3 expression. Decide whether this perturbation leads to a significant alteration in EMP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2863,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and HOGA1 expression is observed. Does this perturbation lead to a significant difference in HOGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and HOGA1 expression is observed. Does this perturbation lead to a significant difference in HOGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5030,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Does this perturbation cause a significant change in CCDC136 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Does this perturbation cause a significant change in CCDC136 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3228,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIPK1-AS1 expression. Decide whether this perturbation leads to a significant alteration in HIPK1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIPK1-AS1 expression. Decide whether this perturbation leads to a significant alteration in HIPK1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1350,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Does this perturbation cause a significant change in GCM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Does this perturbation cause a significant change in GCM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 711,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SKAP1. Does perturbing FEV lead to a significant change in SKAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SKAP1. Does perturbing FEV lead to a significant change in SKAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of SOCS1. Does perturbing FOXL2 lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of SOCS1. Does perturbing FOXL2 lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 277,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of STAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of STAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and EWSAT1 expression is quantified. Does this perturbation result in a significant change in EWSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and EWSAT1 expression is quantified. Does this perturbation result in a significant change in EWSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4613,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and PPP4R4 expression is observed. Does this perturbation lead to a significant difference in PPP4R4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and PPP4R4 expression is observed. Does this perturbation lead to a significant difference in PPP4R4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4838,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor NCALD expression. Decide whether this perturbation leads to a significant alteration in NCALD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor NCALD expression. Decide whether this perturbation leads to a significant alteration in NCALD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2424,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SDSL. Does this perturbation cause a significant change in SDSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SDSL. Does this perturbation cause a significant change in SDSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ETS1. Does perturbing KLF1 lead to a significant change in ETS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ETS1. Does perturbing KLF1 lead to a significant change in ETS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4996,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Determine whether MARCKS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Determine whether MARCKS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2774,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ACSL1. Does this perturbation cause a significant change in ACSL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ACSL1. Does this perturbation cause a significant change in ACSL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4016,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Determine whether RP11-6D1.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Determine whether RP11-6D1.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2795,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in KRT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in KRT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3548,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor DCAF13 expression. Decide whether this perturbation leads to a significant alteration in DCAF13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor DCAF13 expression. Decide whether this perturbation leads to a significant alteration in DCAF13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5133,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2402,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SLC20A1 expression is quantified. Does this perturbation result in a significant change in SLC20A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SLC20A1 expression is quantified. Does this perturbation result in a significant change in SLC20A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5578,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2698,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor RP11-91A18.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-91A18.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor RP11-91A18.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-91A18.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1572,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TPP1 expression is quantified. Does this perturbation result in a significant change in TPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TPP1 expression is quantified. Does this perturbation result in a significant change in TPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of TMEM35. Does this perturbation cause a significant change in TMEM35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of TMEM35. Does this perturbation cause a significant change in TMEM35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is measured. Determine whether RP11-537H15.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is measured. Determine whether RP11-537H15.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3870,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in WDR88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in WDR88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2431,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ZNF610. Does perturbing PTPN1 lead to a significant change in ZNF610 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ZNF610. Does perturbing PTPN1 lead to a significant change in ZNF610 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2061,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CRYM. Does perturbing POU3F2 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CRYM. Does perturbing POU3F2 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 767,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RP11-308D13.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RP11-308D13.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3630,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Does this perturbation cause a significant change in ATG2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Does this perturbation cause a significant change in ATG2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1882,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and MTURN expression is quantified. Does this perturbation result in a significant change in MTURN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and MTURN expression is quantified. Does this perturbation result in a significant change in MTURN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1588,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3958,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor RNF182 expression. Decide whether this perturbation leads to a significant alteration in RNF182 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor RNF182 expression. Decide whether this perturbation leads to a significant alteration in RNF182 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3423,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and APOL6 expression is observed. Does this perturbation lead to a significant difference in APOL6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and APOL6 expression is observed. Does this perturbation lead to a significant difference in APOL6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1058,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor AGXT expression. Decide whether this perturbation leads to a significant alteration in AGXT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor AGXT expression. Decide whether this perturbation leads to a significant alteration in AGXT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4487,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4153,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5861,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of VMP1. Does perturbing HOXA13 lead to a significant change in VMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of VMP1. Does perturbing HOXA13 lead to a significant change in VMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2941,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of LST1. Does perturbing IRF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of LST1. Does perturbing IRF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 875,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4707,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of CNN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of CNN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5575,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 690,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Does this perturbation cause a significant change in SOCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Does this perturbation cause a significant change in SOCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5172,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and APOBR expression is quantified. Does this perturbation result in a significant change in APOBR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and APOBR expression is quantified. Does this perturbation result in a significant change in APOBR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 794,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1465,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1405,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 849,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ARPC3 expression is measured. Determine whether ARPC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ARPC3 expression is measured. Determine whether ARPC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1275,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5564,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of MYL4. Does this perturbation cause a significant change in MYL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of MYL4. Does this perturbation cause a significant change in MYL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2005,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in REEP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in REEP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3235,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in SH3RF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in SH3RF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2683,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM83F expression is observed. Does this perturbation lead to a significant difference in FAM83F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM83F expression is observed. Does this perturbation lead to a significant difference in FAM83F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of PXK. Does perturbing CELF2 lead to a significant change in PXK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of PXK. Does perturbing CELF2 lead to a significant change in PXK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3917,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and HOGA1 expression is measured. Determine whether HOGA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and HOGA1 expression is measured. Determine whether HOGA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of CAPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of CAPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ID3. Does perturbing FOXF1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ID3. Does perturbing FOXF1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2978,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor TCAF2 expression. Decide whether this perturbation leads to a significant alteration in TCAF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor TCAF2 expression. Decide whether this perturbation leads to a significant alteration in TCAF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2690,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Does this perturbation cause a significant change in RP11-91A18.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Does this perturbation cause a significant change in RP11-91A18.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Determine whether RP11-369K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Determine whether RP11-369K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4978,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2601,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of FAM178B. Does perturbing PTPN12 lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of FAM178B. Does perturbing PTPN12 lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2583,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2530,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Does this perturbation cause a significant change in SLC2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Does this perturbation cause a significant change in SLC2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6036,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Determine whether PGA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Determine whether PGA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in AC144568.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in AC144568.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3412,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and TPH2 expression is quantified. Does this perturbation result in a significant change in TPH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and TPH2 expression is quantified. Does this perturbation result in a significant change in TPH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5076,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Determine whether LINC01338 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Determine whether LINC01338 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3086,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 34,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of PDE1B. Does this perturbation cause a significant change in PDE1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of PDE1B. Does this perturbation cause a significant change in PDE1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Determine whether MMP19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Determine whether MMP19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 476,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Determine whether FAM49A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Determine whether FAM49A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2843,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5511,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of UBE2H. Does perturbing JUN lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of UBE2H. Does perturbing JUN lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 105,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in PSMB8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in PSMB8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 603,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and RP11-445F12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-445F12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and RP11-445F12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-445F12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5995,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CREB3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CREB3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 76,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3385,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HHEX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HHEX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 688,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor RAB5B expression. Decide whether this perturbation leads to a significant alteration in RAB5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor RAB5B expression. Decide whether this perturbation leads to a significant alteration in RAB5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4174,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ABCA6. Does this perturbation cause a significant change in ABCA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ABCA6. Does this perturbation cause a significant change in ABCA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of HSD17B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of HSD17B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is measured. Determine whether RP11-445F12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is measured. Determine whether RP11-445F12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5444,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 654,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of STRA6. Does this perturbation cause a significant change in STRA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of STRA6. Does this perturbation cause a significant change in STRA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-328J14.1 expression is measured. Determine whether RP11-328J14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-328J14.1 expression is measured. Determine whether RP11-328J14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3294,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of XX-FW83563B9.5. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of XX-FW83563B9.5. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4991,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of MARCKS. Does perturbing ZC3HAV1 lead to a significant change in MARCKS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of MARCKS. Does perturbing ZC3HAV1 lead to a significant change in MARCKS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2891,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of FAM46C. Does perturbing C19orf26 lead to a significant change in FAM46C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of FAM46C. Does perturbing C19orf26 lead to a significant change in FAM46C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C6orf1 expression is measured. Determine whether C6orf1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C6orf1 expression is measured. Determine whether C6orf1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3532,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and C1orf162 expression is quantified. Does this perturbation result in a significant change in C1orf162 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and C1orf162 expression is quantified. Does this perturbation result in a significant change in C1orf162 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2782,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1560,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5504,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3312,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LRP10 expression is quantified. Does this perturbation result in a significant change in LRP10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LRP10 expression is quantified. Does this perturbation result in a significant change in LRP10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2609,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3819,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is measured. Determine whether RP11-563J2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is measured. Determine whether RP11-563J2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4878,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor CAPG expression. Decide whether this perturbation leads to a significant alteration in CAPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor CAPG expression. Decide whether this perturbation leads to a significant alteration in CAPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4316,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Determine whether CYP1B1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Determine whether CYP1B1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6079,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and RP11-38J22.3 expression is measured. Determine whether RP11-38J22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and RP11-38J22.3 expression is measured. Determine whether RP11-38J22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3729,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and FABP3 expression is measured. Determine whether FABP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and FABP3 expression is measured. Determine whether FABP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5189,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and TMEM88 expression is measured. Determine whether TMEM88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and TMEM88 expression is measured. Determine whether TMEM88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 619,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2017,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of AC078941.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of AC078941.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4695,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5004,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of RLN3. Does this perturbation cause a significant change in RLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of RLN3. Does this perturbation cause a significant change in RLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 77,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2177,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of PXK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of PXK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 719,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SKAP1 expression is measured. Determine whether SKAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SKAP1 expression is measured. Determine whether SKAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5094,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of PLEK. Does this perturbation cause a significant change in PLEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of PLEK. Does this perturbation cause a significant change in PLEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1347,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of CRYAB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of CRYAB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1960,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Does this perturbation cause a significant change in SIGLEC15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Does this perturbation cause a significant change in SIGLEC15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 482,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1873,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C6orf1 expression is observed. Does this perturbation lead to a significant difference in C6orf1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C6orf1 expression is observed. Does this perturbation lead to a significant difference in C6orf1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4770,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1725,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5140,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Does this perturbation cause a significant change in RABAC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Does this perturbation cause a significant change in RABAC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2090,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Does this perturbation cause a significant change in ABCA13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Does this perturbation cause a significant change in ABCA13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5478,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor RP11-369K17.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-369K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor RP11-369K17.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-369K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3573,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4038,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor MSX1 expression. Decide whether this perturbation leads to a significant alteration in MSX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor MSX1 expression. Decide whether this perturbation leads to a significant alteration in MSX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4650,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Does this perturbation cause a significant change in LRRC74B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Does this perturbation cause a significant change in LRRC74B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5281,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PSMB9. Does perturbing ATL1 lead to a significant change in PSMB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PSMB9. Does perturbing ATL1 lead to a significant change in PSMB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CRAT37 expression is measured. Determine whether CRAT37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CRAT37 expression is measured. Determine whether CRAT37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1133,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and RP11-505P4.6 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and RP11-505P4.6 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1322,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3510,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Does this perturbation cause a significant change in MCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Does this perturbation cause a significant change in MCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3655,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3503,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1340,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Does this perturbation cause a significant change in CRYAB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Does this perturbation cause a significant change in CRYAB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 19,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and CLU expression is measured. Determine whether CLU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and CLU expression is measured. Determine whether CLU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6131,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ZNF467. Does perturbing KIF18B lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ZNF467. Does perturbing KIF18B lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4858,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1899,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C8orf22 expression is measured. Determine whether C8orf22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C8orf22 expression is measured. Determine whether C8orf22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5143,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and RABAC1 expression is observed. Does this perturbation lead to a significant difference in RABAC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and RABAC1 expression is observed. Does this perturbation lead to a significant difference in RABAC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5878,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ANXA2R expression. Decide whether this perturbation leads to a significant alteration in ANXA2R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ANXA2R expression. Decide whether this perturbation leads to a significant alteration in ANXA2R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3288,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor RIMBP3C expression. Decide whether this perturbation leads to a significant alteration in RIMBP3C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor RIMBP3C expression. Decide whether this perturbation leads to a significant alteration in RIMBP3C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 552,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3666,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3988,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor AKAP13 expression. Decide whether this perturbation leads to a significant alteration in AKAP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor AKAP13 expression. Decide whether this perturbation leads to a significant alteration in AKAP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1579,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TPP1 expression is measured. Determine whether TPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TPP1 expression is measured. Determine whether TPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3998,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor CLTA expression. Decide whether this perturbation leads to a significant alteration in CLTA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor CLTA expression. Decide whether this perturbation leads to a significant alteration in CLTA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2224,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 167,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of RBM5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of RBM5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3154,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2546,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and MYLIP expression is measured. Determine whether MYLIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and MYLIP expression is measured. Determine whether MYLIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5834,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1395,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2435,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ZNF610 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ZNF610 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in SOX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in SOX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and S100A4 expression is measured. Determine whether S100A4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and S100A4 expression is measured. Determine whether S100A4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2166,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Determine whether SPTAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Determine whether SPTAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 190,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1900,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Does this perturbation cause a significant change in RP1-261G23.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Does this perturbation cause a significant change in RP1-261G23.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 587,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ETS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ETS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4980,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4400,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Does this perturbation cause a significant change in CDK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Does this perturbation cause a significant change in CDK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6101,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of AMHR2. Does perturbing KIF18B lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of AMHR2. Does perturbing KIF18B lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4193,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and SPANXD expression is observed. Does this perturbation lead to a significant difference in SPANXD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and SPANXD expression is observed. Does this perturbation lead to a significant difference in SPANXD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4651,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LRRC74B. Does perturbing CSRNP1 lead to a significant change in LRRC74B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LRRC74B. Does perturbing CSRNP1 lead to a significant change in LRRC74B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2152,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and NUDC expression is quantified. Does this perturbation result in a significant change in NUDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and NUDC expression is quantified. Does this perturbation result in a significant change in NUDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MS4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MS4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3520,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Does this perturbation cause a significant change in ATP8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Does this perturbation cause a significant change in ATP8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3267,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of NUMB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of NUMB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 826,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Determine whether AC007556.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Determine whether AC007556.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 732,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLAUR expression is quantified. Does this perturbation result in a significant change in PLAUR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLAUR expression is quantified. Does this perturbation result in a significant change in PLAUR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3509,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4481,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of GIPC2. Does perturbing ISL2 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of GIPC2. Does perturbing ISL2 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of LTC4S. Does this perturbation cause a significant change in LTC4S expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of LTC4S. Does this perturbation cause a significant change in LTC4S expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1129,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is measured. Determine whether CTC-492K19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is measured. Determine whether CTC-492K19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1870,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Does this perturbation cause a significant change in C6orf1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Does this perturbation cause a significant change in C6orf1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1528,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4147,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of TMEM154 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of TMEM154 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1470,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 180,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Does this perturbation cause a significant change in LGALS12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Does this perturbation cause a significant change in LGALS12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 660,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Does this perturbation cause a significant change in PTPRS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Does this perturbation cause a significant change in PTPRS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1669,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ABCB11 expression is measured. Determine whether ABCB11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ABCB11 expression is measured. Determine whether ABCB11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6244,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3298,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor XX-FW83563B9.5 expression. Decide whether this perturbation leads to a significant alteration in XX-FW83563B9.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor XX-FW83563B9.5 expression. Decide whether this perturbation leads to a significant alteration in XX-FW83563B9.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1524,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4120,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Does this perturbation cause a significant change in AC004540.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Does this perturbation cause a significant change in AC004540.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3254,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of UNC5B. Does this perturbation cause a significant change in UNC5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of UNC5B. Does this perturbation cause a significant change in UNC5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1121,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTC-492K19.4. Does perturbing RREB1 lead to a significant change in CTC-492K19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTC-492K19.4. Does perturbing RREB1 lead to a significant change in CTC-492K19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 512,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ZNF85 expression is quantified. Does this perturbation result in a significant change in ZNF85 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ZNF85 expression is quantified. Does this perturbation result in a significant change in ZNF85 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ZNF85 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ZNF85 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2046,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2541,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SKAP2. Does perturbing IER5L lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SKAP2. Does perturbing IER5L lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3727,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of FABP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of FABP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1204,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ACP5. Does this perturbation cause a significant change in ACP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ACP5. Does this perturbation cause a significant change in ACP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in IFIT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in IFIT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2456,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Determine whether RETN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Determine whether RETN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1894,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C8orf22. Does this perturbation cause a significant change in C8orf22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C8orf22. Does this perturbation cause a significant change in C8orf22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 284,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of CRABP2. Does this perturbation cause a significant change in CRABP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of CRABP2. Does this perturbation cause a significant change in CRABP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5199,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and HCAR2 expression is measured. Determine whether HCAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and HCAR2 expression is measured. Determine whether HCAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4364,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TFAP2A-AS1. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TFAP2A-AS1. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 4499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and TTC9B expression is measured. Determine whether TTC9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and TTC9B expression is measured. Determine whether TTC9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2810,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Does this perturbation cause a significant change in DYNLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Does this perturbation cause a significant change in DYNLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3930,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Does this perturbation cause a significant change in MS4A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Does this perturbation cause a significant change in MS4A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3013,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2926,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Determine whether ATP10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Determine whether ATP10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4095,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4825,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1363,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and TOX expression is observed. Does this perturbation lead to a significant difference in TOX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and TOX expression is observed. Does this perturbation lead to a significant difference in TOX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4738,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor MACF1 expression. Decide whether this perturbation leads to a significant alteration in MACF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor MACF1 expression. Decide whether this perturbation leads to a significant alteration in MACF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6171,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of BLVRB. Does perturbing EGR1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of BLVRB. Does perturbing EGR1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1375,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in RP11-635N19.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in RP11-635N19.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4635,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 880,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 83,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3531,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of C1orf162. Does perturbing FOXF1 lead to a significant change in C1orf162 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of C1orf162. Does perturbing FOXF1 lead to a significant change in C1orf162 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3835,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP3-510H16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP3-510H16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 566,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Determine whether TAS1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Determine whether TAS1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3642,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and LTC4S expression is quantified. Does this perturbation result in a significant change in LTC4S expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and LTC4S expression is quantified. Does this perturbation result in a significant change in LTC4S expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5518,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TMEM55A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TMEM55A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 648,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor CTA-384D8.34 expression. Decide whether this perturbation leads to a significant alteration in CTA-384D8.34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor CTA-384D8.34 expression. Decide whether this perturbation leads to a significant alteration in CTA-384D8.34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2429,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SDSL expression is measured. Determine whether SDSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SDSL expression is measured. Determine whether SDSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1581,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TUBB2B. Does perturbing DLX2 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TUBB2B. Does perturbing DLX2 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 528,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RP11-83A24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-83A24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RP11-83A24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-83A24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3557,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3706,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Determine whether RP11-290K4.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Determine whether RP11-290K4.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 718,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SKAP1 expression. Decide whether this perturbation leads to a significant alteration in SKAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SKAP1 expression. Decide whether this perturbation leads to a significant alteration in SKAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1738,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor RP11-195C7.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195C7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor RP11-195C7.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195C7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 714,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SKAP1. Does this perturbation cause a significant change in SKAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SKAP1. Does this perturbation cause a significant change in SKAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5083,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1460,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 138,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CCS expression. Decide whether this perturbation leads to a significant alteration in CCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CCS expression. Decide whether this perturbation leads to a significant alteration in CCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5607,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of FCGR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of FCGR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2493,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and CHST15 expression is observed. Does this perturbation lead to a significant difference in CHST15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and CHST15 expression is observed. Does this perturbation lead to a significant difference in CHST15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3517,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of MCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of MCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 895,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in TAS2R9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in TAS2R9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3728,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor FABP3 expression. Decide whether this perturbation leads to a significant alteration in FABP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor FABP3 expression. Decide whether this perturbation leads to a significant alteration in FABP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 209,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and PKIG expression is measured. Determine whether PKIG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and PKIG expression is measured. Determine whether PKIG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 627,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2343,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1505,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in BMP2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in BMP2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1492,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and MAOB expression is quantified. Does this perturbation result in a significant change in MAOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and MAOB expression is quantified. Does this perturbation result in a significant change in MAOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1513,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and MYO1F expression is observed. Does this perturbation lead to a significant difference in MYO1F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and MYO1F expression is observed. Does this perturbation lead to a significant difference in MYO1F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1008,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MBP expression. Decide whether this perturbation leads to a significant alteration in MBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MBP expression. Decide whether this perturbation leads to a significant alteration in MBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4160,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 318,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor GRAP2 expression. Decide whether this perturbation leads to a significant alteration in GRAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor GRAP2 expression. Decide whether this perturbation leads to a significant alteration in GRAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4953,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5822,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 975,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Determine whether AC145110.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Determine whether AC145110.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3192,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 1715,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5084,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5326,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Determine whether ATF6B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Determine whether ATF6B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5963,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RGPD5 expression is observed. Does this perturbation lead to a significant difference in RGPD5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RGPD5 expression is observed. Does this perturbation lead to a significant difference in RGPD5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2853,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA5 expression is observed. Does this perturbation lead to a significant difference in ANXA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA5 expression is observed. Does this perturbation lead to a significant difference in ANXA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 52,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5760,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5359,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and GIPR expression is measured. Determine whether GIPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and GIPR expression is measured. Determine whether GIPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1443,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of RP11-76E17.2. Does perturbing FOXA3 lead to a significant change in RP11-76E17.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of RP11-76E17.2. Does perturbing FOXA3 lead to a significant change in RP11-76E17.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3366,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Determine whether FAM19A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Determine whether FAM19A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4549,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5298,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor KRTAP9-9 expression. Decide whether this perturbation leads to a significant alteration in KRTAP9-9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor KRTAP9-9 expression. Decide whether this perturbation leads to a significant alteration in KRTAP9-9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5800,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Does this perturbation cause a significant change in DPYSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Does this perturbation cause a significant change in DPYSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4293,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AC034228.4 expression is observed. Does this perturbation lead to a significant difference in AC034228.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AC034228.4 expression is observed. Does this perturbation lead to a significant difference in AC034228.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Determine whether LEFTY2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Determine whether LEFTY2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Determine whether FAM83F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Determine whether FAM83F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4760,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2831,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA2. Does perturbing MAPK1 lead to a significant change in ANXA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA2. Does perturbing MAPK1 lead to a significant change in ANXA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2622,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and XK expression is quantified. Does this perturbation result in a significant change in XK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and XK expression is quantified. Does this perturbation result in a significant change in XK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CTD-3131K8.3. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CTD-3131K8.3. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6104,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2939,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ARL6IP1 expression is measured. Determine whether ARL6IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ARL6IP1 expression is measured. Determine whether ARL6IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of AGXT. Does perturbing SLC4A1 lead to a significant change in AGXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of AGXT. Does perturbing SLC4A1 lead to a significant change in AGXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6014,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of AMPH. Does this perturbation cause a significant change in AMPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of AMPH. Does this perturbation cause a significant change in AMPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2022,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and CTSS expression is quantified. Does this perturbation result in a significant change in CTSS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and CTSS expression is quantified. Does this perturbation result in a significant change in CTSS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2445,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in AC064834.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in AC064834.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3946,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Determine whether MYOZ3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Determine whether MYOZ3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1988,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SNCG expression. Decide whether this perturbation leads to a significant alteration in SNCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SNCG expression. Decide whether this perturbation leads to a significant alteration in SNCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 988,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MS4A3 expression. Decide whether this perturbation leads to a significant alteration in MS4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MS4A3 expression. Decide whether this perturbation leads to a significant alteration in MS4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4722,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and WDR88 expression is quantified. Does this perturbation result in a significant change in WDR88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and WDR88 expression is quantified. Does this perturbation result in a significant change in WDR88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5870,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Does this perturbation cause a significant change in ANXA2R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Does this perturbation cause a significant change in ANXA2R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 685,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in RAB5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in RAB5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4902,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RP11-285F7.2 expression is quantified. Does this perturbation result in a significant change in RP11-285F7.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RP11-285F7.2 expression is quantified. Does this perturbation result in a significant change in RP11-285F7.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5668,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor DRC1 expression. Decide whether this perturbation leads to a significant alteration in DRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor DRC1 expression. Decide whether this perturbation leads to a significant alteration in DRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2813,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and DYNLL1 expression is observed. Does this perturbation lead to a significant difference in DYNLL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and DYNLL1 expression is observed. Does this perturbation lead to a significant difference in DYNLL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5648,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4611,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of PPP4R4. Does perturbing KIF2C lead to a significant change in PPP4R4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of PPP4R4. Does perturbing KIF2C lead to a significant change in PPP4R4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 503,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3133,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4639,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5638,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5781,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of INHBE. Does perturbing PTPN9 lead to a significant change in INHBE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of INHBE. Does perturbing PTPN9 lead to a significant change in INHBE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5586,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3226,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Determine whether HIPK1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Determine whether HIPK1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1736,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Determine whether RP11-195C7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Determine whether RP11-195C7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5756,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Determine whether YPEL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Determine whether YPEL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2937,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ARL6IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ARL6IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 613,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 713,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SKAP1 expression is observed. Does this perturbation lead to a significant difference in SKAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SKAP1 expression is observed. Does this perturbation lead to a significant difference in SKAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3287,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of RIMBP3C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of RIMBP3C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4296,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Determine whether AC034228.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Determine whether AC034228.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2901,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ADD3. Does perturbing C19orf26 lead to a significant change in ADD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ADD3. Does perturbing C19orf26 lead to a significant change in ADD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and PHACTR1 expression is quantified. Does this perturbation result in a significant change in PHACTR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and PHACTR1 expression is quantified. Does this perturbation result in a significant change in PHACTR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4059,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and PROX1 expression is measured. Determine whether PROX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and PROX1 expression is measured. Determine whether PROX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2753,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CTD-3131K8.3 expression is observed. Does this perturbation lead to a significant difference in CTD-3131K8.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CTD-3131K8.3 expression is observed. Does this perturbation lead to a significant difference in CTD-3131K8.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4888,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2652,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and MSRB1 expression is quantified. Does this perturbation result in a significant change in MSRB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and MSRB1 expression is quantified. Does this perturbation result in a significant change in MSRB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3391,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of CTB-49A3.5. Does perturbing SAMD1 lead to a significant change in CTB-49A3.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of CTB-49A3.5. Does perturbing SAMD1 lead to a significant change in CTB-49A3.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3750,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 5357,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of GIPR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of GIPR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 4934,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of CPVL. Does this perturbation cause a significant change in CPVL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of CPVL. Does this perturbation cause a significant change in CPVL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of EWSAT1. Does perturbing ATL1 lead to a significant change in EWSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of EWSAT1. Does perturbing ATL1 lead to a significant change in EWSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2924,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ATP10D. Does this perturbation cause a significant change in ATP10D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ATP10D. Does this perturbation cause a significant change in ATP10D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1252,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is quantified. Does this perturbation result in a significant change in RP11-497G19.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is quantified. Does this perturbation result in a significant change in RP11-497G19.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4595,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2596,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3208,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2266,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Determine whether FILIP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Determine whether FILIP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5116,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Determine whether KCNQ1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Determine whether KCNQ1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6043,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and NPW expression is observed. Does this perturbation lead to a significant difference in NPW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and NPW expression is observed. Does this perturbation lead to a significant difference in NPW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 2334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of C1orf141. Does this perturbation cause a significant change in C1orf141 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of C1orf141. Does this perturbation cause a significant change in C1orf141 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2751,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CTD-3131K8.3. Does perturbing MAP7D1 lead to a significant change in CTD-3131K8.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CTD-3131K8.3. Does perturbing MAP7D1 lead to a significant change in CTD-3131K8.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4698,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5494,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of IGFL2. Does this perturbation cause a significant change in IGFL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of IGFL2. Does this perturbation cause a significant change in IGFL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM118A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM118A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2865,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in HOGA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in HOGA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ANXA2R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ANXA2R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 1885,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in MTURN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in MTURN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 4617,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of PPP4R4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of PPP4R4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 438,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 519,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ZNF85 expression is measured. Determine whether ZNF85 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ZNF85 expression is measured. Determine whether ZNF85 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4398,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor AK8 expression. Decide whether this perturbation leads to a significant alteration in AK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor AK8 expression. Decide whether this perturbation leads to a significant alteration in AK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 3134,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of NUCB2. Does this perturbation cause a significant change in NUCB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of NUCB2. Does this perturbation cause a significant change in NUCB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2151,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of NUDC. Does perturbing CNN1 lead to a significant change in NUDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of NUDC. Does perturbing CNN1 lead to a significant change in NUDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4914,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RIT1. Does this perturbation cause a significant change in RIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RIT1. Does this perturbation cause a significant change in RIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2455,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in RETN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in RETN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2679,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and DYNLT3 expression is measured. Determine whether DYNLT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and DYNLT3 expression is measured. Determine whether DYNLT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4069,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and CCNG2 expression is measured. Determine whether CCNG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and CCNG2 expression is measured. Determine whether CCNG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3382,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HHEX expression is quantified. Does this perturbation result in a significant change in HHEX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HHEX expression is quantified. Does this perturbation result in a significant change in HHEX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4959,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 754,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLA2G1B. Does this perturbation cause a significant change in PLA2G1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLA2G1B. Does this perturbation cause a significant change in PLA2G1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3768,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor IL20 expression. Decide whether this perturbation leads to a significant alteration in IL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor IL20 expression. Decide whether this perturbation leads to a significant alteration in IL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1799,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-128B16.3 expression is measured. Determine whether RP11-128B16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-128B16.3 expression is measured. Determine whether RP11-128B16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2503,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and AREG expression is observed. Does this perturbation lead to a significant difference in AREG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and AREG expression is observed. Does this perturbation lead to a significant difference in AREG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1064,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-510J16.5. Does this perturbation cause a significant change in RP11-510J16.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-510J16.5. Does this perturbation cause a significant change in RP11-510J16.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1311,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LINC01562. Does perturbing ZBTB25 lead to a significant change in LINC01562 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LINC01562. Does perturbing ZBTB25 lead to a significant change in LINC01562 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3271,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CARMN. Does perturbing CLDN6 lead to a significant change in CARMN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CARMN. Does perturbing CLDN6 lead to a significant change in CARMN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2049,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1111,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of C1orf228. Does perturbing RREB1 lead to a significant change in C1orf228 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of C1orf228. Does perturbing RREB1 lead to a significant change in C1orf228 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2499,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and CHST15 expression is measured. Determine whether CHST15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and CHST15 expression is measured. Determine whether CHST15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1263,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 5371,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ACTC1. Does perturbing NIT1 lead to a significant change in ACTC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ACTC1. Does perturbing NIT1 lead to a significant change in ACTC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 168,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor RBM5-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor RBM5-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 2374,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CD59. Does this perturbation cause a significant change in CD59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CD59. Does this perturbation cause a significant change in CD59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5040,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 6257,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of TRAPPC3L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of TRAPPC3L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 3592,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and TUBB3 expression is quantified. Does this perturbation result in a significant change in TUBB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and TUBB3 expression is quantified. Does this perturbation result in a significant change in TUBB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3942,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MYOZ3 expression is quantified. Does this perturbation result in a significant change in MYOZ3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MYOZ3 expression is quantified. Does this perturbation result in a significant change in MYOZ3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6038,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor PGA4 expression. Decide whether this perturbation leads to a significant alteration in PGA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor PGA4 expression. Decide whether this perturbation leads to a significant alteration in PGA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 5334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of HIST1H3H. Does this perturbation cause a significant change in HIST1H3H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of HIST1H3H. Does this perturbation cause a significant change in HIST1H3H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5425,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01420 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01420 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3449,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and KCNH2 expression is measured. Determine whether KCNH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and KCNH2 expression is measured. Determine whether KCNH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3603,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4341,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of HIST1H4H. Does perturbing KMT2A lead to a significant change in HIST1H4H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of HIST1H4H. Does perturbing KMT2A lead to a significant change in HIST1H4H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1011,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of RP1-102K2.6. Does perturbing LHX1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of RP1-102K2.6. Does perturbing LHX1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2471,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of SOX5. Does perturbing TBX2 lead to a significant change in SOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of SOX5. Does perturbing TBX2 lead to a significant change in SOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1334,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 5821,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of HERPUD1. Does perturbing SNAI1 lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of HERPUD1. Does perturbing SNAI1 lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 255,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5245,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in RP11-662J14.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in RP11-662J14.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 796,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1081,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of SERPINF1. Does perturbing RREB1 lead to a significant change in SERPINF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of SERPINF1. Does perturbing RREB1 lead to a significant change in SERPINF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 935,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CYP2C18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CYP2C18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 3386,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Determine whether HHEX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Determine whether HHEX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5063,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RP11-320G24.1 expression is observed. Does this perturbation lead to a significant difference in RP11-320G24.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RP11-320G24.1 expression is observed. Does this perturbation lead to a significant difference in RP11-320G24.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1876,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Determine whether C6orf1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Determine whether C6orf1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 331,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of LRRC36. Does perturbing FOXA1 lead to a significant change in LRRC36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of LRRC36. Does perturbing FOXA1 lead to a significant change in LRRC36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1447,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5018,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor TMEM35 expression. Decide whether this perturbation leads to a significant alteration in TMEM35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor TMEM35 expression. Decide whether this perturbation leads to a significant alteration in TMEM35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 6018,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor AMPH expression. Decide whether this perturbation leads to a significant alteration in AMPH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor AMPH expression. Decide whether this perturbation leads to a significant alteration in AMPH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 4947,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of LEFTY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of LEFTY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2488,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1249,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is measured. Determine whether RP11-259K5.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is measured. Determine whether RP11-259K5.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 3356,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Determine whether VASH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Determine whether VASH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2350,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Does this perturbation cause a significant change in SOX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Does this perturbation cause a significant change in SOX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 4626,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 3490,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 393,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and SH3BGRL expression is observed. Does this perturbation lead to a significant difference in SH3BGRL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and SH3BGRL expression is observed. Does this perturbation lead to a significant difference in SH3BGRL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1034,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PTRF. Does this perturbation cause a significant change in PTRF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PTRF. Does this perturbation cause a significant change in PTRF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 2406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Determine whether SLC20A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Determine whether SLC20A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5896,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Determine whether RP3-525N10.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Determine whether RP3-525N10.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1802,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SAT1 expression is quantified. Does this perturbation result in a significant change in SAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SAT1 expression is quantified. Does this perturbation result in a significant change in SAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 2466,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1667,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ABCB11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ABCB11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 2013,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and AC078941.1 expression is observed. Does this perturbation lead to a significant difference in AC078941.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and AC078941.1 expression is observed. Does this perturbation lead to a significant difference in AC078941.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 1539,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and SLC43A2 expression is measured. Determine whether SLC43A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and SLC43A2 expression is measured. Determine whether SLC43A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1855,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in RP11-714G18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in RP11-714G18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1793,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-128B16.3 expression is observed. Does this perturbation lead to a significant difference in RP11-128B16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-128B16.3 expression is observed. Does this perturbation lead to a significant difference in RP11-128B16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 869,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CYP3A5 expression is measured. Determine whether CYP3A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CYP3A5 expression is measured. Determine whether CYP3A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5644,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 3561,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of FEZ1. Does perturbing ZBTB1 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of FEZ1. Does perturbing ZBTB1 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 5401,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CDC20. Does perturbing CDKN1B lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CDC20. Does perturbing CDKN1B lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 6180,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 1025,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5623,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FAM83A expression is observed. Does this perturbation lead to a significant difference in FAM83A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FAM83A expression is observed. Does this perturbation lead to a significant difference in FAM83A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 4769,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 1683,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and LMNA expression is observed. Does this perturbation lead to a significant difference in LMNA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and LMNA expression is observed. Does this perturbation lead to a significant difference in LMNA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 877,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5355,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in GIPR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in GIPR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Determine whether RAB5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Determine whether RAB5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2310,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Does this perturbation cause a significant change in TFAP2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Does this perturbation cause a significant change in TFAP2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 3739,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 2240,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Does this perturbation cause a significant change in ASIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Does this perturbation cause a significant change in ASIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 279,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and STAC3 expression is measured. Determine whether STAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and STAC3 expression is measured. Determine whether STAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of PRSS57. Does perturbing KIAA1804 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of PRSS57. Does perturbing KIAA1804 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 1406,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 6239,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4078,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor RP11-452C8.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-452C8.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor RP11-452C8.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-452C8.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'." 1686,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Determine whether LMNA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Determine whether LMNA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 5,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 1489,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4845,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in C19orf38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in C19orf38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5023,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,Yes,You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 513,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ZNF85 expression is observed. Does this perturbation lead to a significant difference in ZNF85 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.,No,You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ZNF85 expression is observed. Does this perturbation lead to a significant difference in ZNF85 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'. 3812,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is quantified. Does this perturbation result in a significant change in RP11-563J2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is quantified. Does this perturbation result in a significant change in RP11-563J2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5345,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in TOR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in TOR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 5051,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of COL1A1. Does perturbing OSR2 lead to a significant change in COL1A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of COL1A1. Does perturbing OSR2 lead to a significant change in COL1A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3879,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4551,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of SLC8A1. Does perturbing TMSB4X lead to a significant change in SLC8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of SLC8A1. Does perturbing TMSB4X lead to a significant change in SLC8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 6006,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Determine whether TACC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Determine whether TACC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 4180,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Does this perturbation cause a significant change in RP11-362K14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Does this perturbation cause a significant change in RP11-362K14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'." 2852,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA5 expression is quantified. Does this perturbation result in a significant change in ANXA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA5 expression is quantified. Does this perturbation result in a significant change in ANXA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 5072,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and LINC01338 expression is quantified. Does this perturbation result in a significant change in LINC01338 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and LINC01338 expression is quantified. Does this perturbation result in a significant change in LINC01338 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 6037,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of PGA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of PGA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 5132,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'." 4634,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'." 1141,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of FAM101B. Does perturbing ZNF318 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of FAM101B. Does perturbing ZNF318 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 3065,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2161,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of SPTAN1. Does perturbing CELF2 lead to a significant change in SPTAN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of SPTAN1. Does perturbing CELF2 lead to a significant change in SPTAN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2437,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ZNF610 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ZNF610 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'." 665,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in PTPRS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in PTPRS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 6175,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2701,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TNNI3. Does perturbing MAP7D1 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TNNI3. Does perturbing MAP7D1 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 2889,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'." 185,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in LGALS12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in LGALS12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'." 2461,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of FEV. Does perturbing TBX2 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",Yes,"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of FEV. Does perturbing TBX2 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'." 4906,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Determine whether RP11-285F7.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",No,"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Determine whether RP11-285F7.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'."