[
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and DYNLT3 expression is observed. Does this perturbation lead to a significant difference in DYNLT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and DYNLT3 expression is observed. Does this perturbation lead to a significant difference in DYNLT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2673
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is quantified. Does this perturbation result in a significant change in RP4-550H1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and RP4-550H1.4 expression is quantified. Does this perturbation result in a significant change in RP4-550H1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5792
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and COLGALT2 expression is observed. Does this perturbation lead to a significant difference in COLGALT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4093
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of TRGVA. Does perturbing TBX3 lead to a significant change in TRGVA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of TRGVA. Does perturbing TBX3 lead to a significant change in TRGVA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":951
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of CSRNP1. Does perturbing CSRNP1 lead to a significant change in CSRNP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of CSRNP1. Does perturbing CSRNP1 lead to a significant change in CSRNP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4641
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ATP8A1. Does this perturbation cause a significant change in ATP8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ATP8A1. Does this perturbation cause a significant change in ATP8A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3524
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5707
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in SPTAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in SPTAN1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2165
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Does this perturbation cause a significant change in ID1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":70
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in IGFL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in IGFL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5495
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor ZNF431 expression. Decide whether this perturbation leads to a significant alteration in ZNF431 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4678
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and NCF4 expression is observed. Does this perturbation lead to a significant difference in NCF4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":723
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AIF1. Does this perturbation cause a significant change in AIF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2284
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CHP1 expression. Decide whether this perturbation leads to a significant alteration in CHP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CHP1 expression. Decide whether this perturbation leads to a significant alteration in CHP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5468
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6183
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Does this perturbation cause a significant change in RP3-510H16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Does this perturbation cause a significant change in RP3-510H16.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3830
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AC034228.4 expression is quantified. Does this perturbation result in a significant change in AC034228.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and AC034228.4 expression is quantified. Does this perturbation result in a significant change in AC034228.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4292
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Determine whether CMB9-22P13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of CMB9-22P13.1 is measured. Determine whether CMB9-22P13.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5396
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of BMP2K. Does perturbing MIDN lead to a significant change in BMP2K expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of BMP2K. Does perturbing MIDN lead to a significant change in BMP2K expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1501
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Determine whether RP1-59D14.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of RP1-59D14.10 is measured. Determine whether RP1-59D14.10 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3776
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CTD-2031P19.5 expression. Decide whether this perturbation leads to a significant alteration in CTD-2031P19.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor CTD-2031P19.5 expression. Decide whether this perturbation leads to a significant alteration in CTD-2031P19.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":888
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2528
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Determine whether CCNB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of CCNB2 is measured. Determine whether CCNB2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4336
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in GRN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5885
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2948
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1140
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in MYO1F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in MYO1F expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1515
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and CTSW expression is observed. Does this perturbation lead to a significant difference in CTSW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and CTSW expression is observed. Does this perturbation lead to a significant difference in CTSW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5363
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of TACC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of TACC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6007
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5647
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in CTB-49A3.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in CTB-49A3.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3395
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4624
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in DYNLL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in DYNLL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2815
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZNF318, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1167
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of LINC00479 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of LINC00479 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":417
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Does this perturbation cause a significant change in RP11-355B11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZNF318 is perturbed and the expression of RP11-355B11.2 is measured. Does this perturbation cause a significant change in RP11-355B11.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1170
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in APOBR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in APOBR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5175
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in PCDHGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in PCDHGA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2565
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of PRKAG2-AS1 is measured. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3160
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ATP9A. Does perturbing GLB1L2 lead to a significant change in ATP9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ATP9A. Does perturbing GLB1L2 lead to a significant change in ATP9A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":531
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5945
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLEKHO1 expression is measured. Determine whether PLEKHO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLEKHO1 expression is measured. Determine whether PLEKHO1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6129
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-510J16.5. Does perturbing SLC4A1 lead to a significant change in RP11-510J16.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of RP11-510J16.5. Does perturbing SLC4A1 lead to a significant change in RP11-510J16.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1061
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SGK1 is perturbed and the expression of ARHGDIB is measured. Determine whether ARHGDIB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4026
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3438
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CTD-2012K14.6. Does perturbing CEBPB lead to a significant change in CTD-2012K14.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of CTD-2012K14.6. Does perturbing CEBPB lead to a significant change in CTD-2012K14.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5211
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and STRC expression is measured. Determine whether STRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXA13 is perturbed and STRC expression is measured. Determine whether STRC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5909
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of FLJ12825 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of FLJ12825 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":177
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PHLDA2. Does perturbing CNNM4 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of PHLDA2. Does perturbing CNNM4 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4761
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-52L5.6. Does perturbing EGR1 lead to a significant change in RP11-52L5.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of RP11-52L5.6. Does perturbing EGR1 lead to a significant change in RP11-52L5.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6201
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NCL is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4889
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AP1S2 expression. Decide whether this perturbation leads to a significant alteration in AP1S2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4268
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Does this perturbation cause a significant change in RP11-567N4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Does this perturbation cause a significant change in RP11-567N4.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1780
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Determine whether RP11-635N19.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Determine whether RP11-635N19.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1376
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in MAP7D1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2725
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ATF6B. Does this perturbation cause a significant change in ATF6B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ATF6B. Does this perturbation cause a significant change in ATF6B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5324
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3068
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Determine whether RCSD1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1446
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2048
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2540
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in TUBB2B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1585
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Does this perturbation cause a significant change in FABP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Does this perturbation cause a significant change in FABP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3720
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":82
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01420. Does this perturbation cause a significant change in LINC01420 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of LINC01420. Does this perturbation cause a significant change in LINC01420 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5424
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is measured. Determine whether RP5-1142A6.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and RP5-1142A6.2 expression is measured. Determine whether RP5-1142A6.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4719
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Determine whether AC007246.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of AC007246.3 is measured. Determine whether AC007246.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2296
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of AMHR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6107
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RPL17-C18orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of RPL17-C18orf32 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5777
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in STRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in STRC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5905
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-328J14.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-328J14.1 expression is quantified. Does this perturbation result in a significant change in RP11-328J14.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2572
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and ANXA3 expression is observed. Does this perturbation lead to a significant difference in ANXA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3963
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in TLCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in TLCD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5555
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ARRDC3. Does this perturbation cause a significant change in ARRDC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of ARRDC3. Does this perturbation cause a significant change in ARRDC3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":234
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor FOXL2 expression. Decide whether this perturbation leads to a significant alteration in FOXL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3688
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of TUBB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of TUBB3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3597
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and CRABP2 expression is quantified. Does this perturbation result in a significant change in CRABP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and CRABP2 expression is quantified. Does this perturbation result in a significant change in CRABP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":282
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of FAM225B. Does this perturbation cause a significant change in FAM225B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of FAM225B. Does this perturbation cause a significant change in FAM225B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5234
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3713
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of CPVL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of CPVL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4937
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ZNF431. Does perturbing SNAI1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of ZNF431. Does perturbing SNAI1 lead to a significant change in ZNF431 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5831
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FAM83A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN13, does the expression profile of FAM83A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5627
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LRRTM4 expression is quantified. Does this perturbation result in a significant change in LRRTM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and LRRTM4 expression is quantified. Does this perturbation result in a significant change in LRRTM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5842
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CCDC159 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in CCDC159 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4255
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and SERPINF1 expression is measured. Determine whether SERPINF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and SERPINF1 expression is measured. Determine whether SERPINF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1089
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CDC20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5405
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in LMNA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in LMNA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1685
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HCN1 expression is quantified. Does this perturbation result in a significant change in HCN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and HCN1 expression is quantified. Does this perturbation result in a significant change in HCN1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3042
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is quantified. Does this perturbation result in a significant change in RP11-1085N6.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and RP11-1085N6.3 expression is quantified. Does this perturbation result in a significant change in RP11-1085N6.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3402
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and TAS2R9 expression is observed. Does this perturbation lead to a significant difference in TAS2R9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and TAS2R9 expression is observed. Does this perturbation lead to a significant difference in TAS2R9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":893
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5265
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6092
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and DYNLL1 expression is quantified. Does this perturbation result in a significant change in DYNLL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and DYNLL1 expression is quantified. Does this perturbation result in a significant change in DYNLL1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2812
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor RP11-445F12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-445F12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor RP11-445F12.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-445F12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":608
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and RP11-76E17.2 expression is observed. Does this perturbation lead to a significant difference in RP11-76E17.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and RP11-76E17.2 expression is observed. Does this perturbation lead to a significant difference in RP11-76E17.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3343
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor NCKAP1L expression. Decide whether this perturbation leads to a significant alteration in NCKAP1L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3088
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor COL21A1 expression. Decide whether this perturbation leads to a significant alteration in COL21A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor COL21A1 expression. Decide whether this perturbation leads to a significant alteration in COL21A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4428
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of MYO1F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of MYO1F indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1517
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and LINC01003 expression is measured. Determine whether LINC01003 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and LINC01003 expression is measured. Determine whether LINC01003 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":459
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Determine whether TRIM31 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Determine whether TRIM31 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":466
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and NUCB2 expression is measured. Determine whether NUCB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3139
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Determine whether APOL6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of APOL6 is measured. Determine whether APOL6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3426
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5988
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CARMN expression is observed. Does this perturbation lead to a significant difference in CARMN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and CARMN expression is observed. Does this perturbation lead to a significant difference in CARMN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3273
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and GRN expression is observed. Does this perturbation lead to a significant difference in GRN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5883
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and IGHEP2 expression is observed. Does this perturbation lead to a significant difference in IGHEP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and IGHEP2 expression is observed. Does this perturbation lead to a significant difference in IGHEP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3583
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in RP11-369K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in RP11-369K17.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5475
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Does this perturbation cause a significant change in HIST1H3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Does this perturbation cause a significant change in HIST1H3H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5330
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-290K4.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290K4.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-290K4.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290K4.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3708
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor LEFTY1 expression. Decide whether this perturbation leads to a significant alteration in LEFTY1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor LEFTY1 expression. Decide whether this perturbation leads to a significant alteration in LEFTY1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5918
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CPXM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in CPXM1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":385
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ADGB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in ADGB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5545
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA5 expression is measured. Determine whether ANXA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and ANXA5 expression is measured. Determine whether ANXA5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2859
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of VGF. Does this perturbation cause a significant change in VGF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of VGF. Does this perturbation cause a significant change in VGF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":264
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and CCNB2 expression is measured. Determine whether CCNB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and CCNB2 expression is measured. Determine whether CCNB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4339
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of CCDC136. Does this perturbation cause a significant change in CCDC136 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of CCDC136. Does this perturbation cause a significant change in CCDC136 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5034
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ZIC4. Does this perturbation cause a significant change in ZIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of ZIC4. Does this perturbation cause a significant change in ZIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2614
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of LINC01003 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MEIS1, does the expression profile of LINC01003 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":457
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and RUNX1 expression is observed. Does this perturbation lead to a significant difference in RUNX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2783
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Does this perturbation cause a significant change in AC034228.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Does this perturbation cause a significant change in AC034228.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4290
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP11-445O3.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP11-445O3.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":45
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and RP11-38J22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-38J22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and RP11-38J22.3 expression is observed. Does this perturbation lead to a significant difference in RP11-38J22.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6073
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CD46 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4207
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in MFGE8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2485
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":910
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of KCNH2. Does this perturbation cause a significant change in KCNH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of KCNH2. Does this perturbation cause a significant change in KCNH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3444
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and DNAJB1 expression is measured. Determine whether DNAJB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and DNAJB1 expression is measured. Determine whether DNAJB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3869
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Does this perturbation cause a significant change in TRAPPC3L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of TRAPPC3L is measured. Does this perturbation cause a significant change in TRAPPC3L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6250
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":253
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in HCAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in HCAR2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5195
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor S100A4 expression. Decide whether this perturbation leads to a significant alteration in S100A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor S100A4 expression. Decide whether this perturbation leads to a significant alteration in S100A4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1048
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LRP10. Does perturbing FOXA3 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LRP10. Does perturbing FOXA3 lead to a significant change in LRP10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3311
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is measured. Determine whether XX-FW83563B9.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and XX-FW83563B9.5 expression is measured. Determine whether XX-FW83563B9.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3299
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor TYROBP expression. Decide whether this perturbation leads to a significant alteration in TYROBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5088
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ASIC4 expression is measured. Determine whether ASIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and ASIC4 expression is measured. Determine whether ASIC4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2249
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01395. Does this perturbation cause a significant change in LINC01395 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01395. Does this perturbation cause a significant change in LINC01395 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5594
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and MOGAT2 expression is quantified. Does this perturbation result in a significant change in MOGAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and MOGAT2 expression is quantified. Does this perturbation result in a significant change in MOGAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5532
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of LST1. Does perturbing KLF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of LST1. Does perturbing KLF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":551
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2542
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":993
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and AC007193.6 expression is quantified. Does this perturbation result in a significant change in AC007193.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and AC007193.6 expression is quantified. Does this perturbation result in a significant change in AC007193.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2632
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4048
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2300
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of MCC. Does this perturbation cause a significant change in MCC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3514
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Determine whether SLC2A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Determine whether SLC2A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1996
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Does this perturbation cause a significant change in RP11-219B4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Does this perturbation cause a significant change in RP11-219B4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1770
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CTD-3126B10.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in CTD-3126B10.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2395
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ZNF85. Does perturbing GLB1L2 lead to a significant change in ZNF85 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of ZNF85. Does perturbing GLB1L2 lead to a significant change in ZNF85 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":511
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TM6SF2 is measured. Does this perturbation cause a significant change in TM6SF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4540
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor AMHR2 expression. Decide whether this perturbation leads to a significant alteration in AMHR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5708
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and TNFAIP2 expression is quantified. Does this perturbation result in a significant change in TNFAIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPB is perturbed and TNFAIP2 expression is quantified. Does this perturbation result in a significant change in TNFAIP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5202
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and LINC01338 expression is observed. Does this perturbation lead to a significant difference in LINC01338 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and LINC01338 expression is observed. Does this perturbation lead to a significant difference in LINC01338 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5073
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5456
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1022
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Does this perturbation cause a significant change in LPAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of LPAR2 is measured. Does this perturbation cause a significant change in LPAR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3100
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CD37 expression is quantified. Does this perturbation result in a significant change in CD37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CD37 expression is quantified. Does this perturbation result in a significant change in CD37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3242
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Does this perturbation cause a significant change in NUDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of NUDC is measured. Does this perturbation cause a significant change in NUDC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2150
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1279
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PSMB9 expression is measured. Determine whether PSMB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and PSMB9 expression is measured. Determine whether PSMB9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5289
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SAT1 is measured. Determine whether SAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1806
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AC007246.3 expression. Decide whether this perturbation leads to a significant alteration in AC007246.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AC007246.3 expression. Decide whether this perturbation leads to a significant alteration in AC007246.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2298
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and CEBPD expression is measured. Determine whether CEBPD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and CEBPD expression is measured. Determine whether CEBPD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6069
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2527
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SNCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SNCG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1985
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of WBP2. Does perturbing STIL lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of WBP2. Does perturbing STIL lead to a significant change in WBP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5161
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Does this perturbation cause a significant change in PLEKHO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Does this perturbation cause a significant change in PLEKHO1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6120
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of HMOX1. Does this perturbation cause a significant change in HMOX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of HMOX1. Does this perturbation cause a significant change in HMOX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5974
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in MFSD2A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6095
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor PIM2 expression. Decide whether this perturbation leads to a significant alteration in PIM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5748
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ALAS2. Does perturbing CDKN1C lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of ALAS2. Does perturbing CDKN1C lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6231
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Determine whether ZNF610 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Determine whether ZNF610 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2436
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":322
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Does this perturbation cause a significant change in CCDC159 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of CCDC159 is measured. Does this perturbation cause a significant change in CCDC159 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4250
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in LTC4S expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in LTC4S expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3645
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Does this perturbation cause a significant change in SP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of SP6 is measured. Does this perturbation cause a significant change in SP6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1700
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Determine whether SLC22A25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of SLC22A25 is measured. Determine whether SLC22A25 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1836
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in ANXA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2835
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ADD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ADD3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2907
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA2 expression. Decide whether this perturbation leads to a significant alteration in ANXA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor ANXA2 expression. Decide whether this perturbation leads to a significant alteration in ANXA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2838
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CDK1 expression is quantified. Does this perturbation result in a significant change in CDK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CDK1 expression is quantified. Does this perturbation result in a significant change in CDK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4402
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ACTC1 expression is observed. Does this perturbation lead to a significant difference in ACTC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ACTC1 expression is observed. Does this perturbation lead to a significant difference in ACTC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5373
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of TAS2R9. Does perturbing SET lead to a significant change in TAS2R9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of TAS2R9. Does perturbing SET lead to a significant change in TAS2R9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":891
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LRP10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LRP10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3317
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and CSRNP1 expression is observed. Does this perturbation lead to a significant difference in CSRNP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and CSRNP1 expression is observed. Does this perturbation lead to a significant difference in CSRNP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4643
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of FADS1. Does perturbing SLC6A9 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of FADS1. Does perturbing SLC6A9 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1451
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and ID1 expression is quantified. Does this perturbation result in a significant change in ID1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":72
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ATG2A expression is measured. Determine whether ATG2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ATG2A expression is measured. Determine whether ATG2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3639
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Determine whether MBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Determine whether MBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1006
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of RIMBP3C. Does perturbing CLDN6 lead to a significant change in RIMBP3C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of RIMBP3C. Does perturbing CLDN6 lead to a significant change in RIMBP3C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3281
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of LMNA. Does this perturbation cause a significant change in LMNA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of LMNA. Does this perturbation cause a significant change in LMNA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1684
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AC034228.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AC034228.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4295
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3565
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CYP3A5. Does this perturbation cause a significant change in CYP3A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of CYP3A5. Does this perturbation cause a significant change in CYP3A5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":864
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SLC2A1-AS1. Does perturbing S1PR2 lead to a significant change in SLC2A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SLC2A1-AS1. Does perturbing S1PR2 lead to a significant change in SLC2A1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1991
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ALAS2. Does perturbing FOXF1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ALAS2. Does perturbing FOXF1 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3501
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Determine whether PSMB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Determine whether PSMB9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5286
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CD46. Does perturbing CEBPA lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CD46. Does perturbing CEBPA lead to a significant change in CD46 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4201
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of HSD17B4. Does this perturbation cause a significant change in HSD17B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of HSD17B4. Does this perturbation cause a significant change in HSD17B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":144
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of INADL. Does perturbing MAP2K3 lead to a significant change in INADL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of INADL. Does perturbing MAP2K3 lead to a significant change in INADL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2251
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CKS2 expression is measured. Determine whether CKS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and CKS2 expression is measured. Determine whether CKS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2079
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ASIC4 expression is quantified. Does this perturbation result in a significant change in ASIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and ASIC4 expression is quantified. Does this perturbation result in a significant change in ASIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2242
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of CD24 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3737
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is measured. Determine whether RP11-369K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TGFBR2 is perturbed and RP11-369K17.1 expression is measured. Determine whether RP11-369K17.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5479
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and FCGR2A expression is measured. Determine whether FCGR2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":549
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor DLX4 expression. Decide whether this perturbation leads to a significant alteration in DLX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor DLX4 expression. Decide whether this perturbation leads to a significant alteration in DLX4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6168
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CCS. Does perturbing CEBPE lead to a significant change in CCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CCS. Does perturbing CEBPE lead to a significant change in CCS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":131
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and TFAP2A expression is quantified. Does this perturbation result in a significant change in TFAP2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and TFAP2A expression is quantified. Does this perturbation result in a significant change in TFAP2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2312
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Determine whether ADGB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Determine whether ADGB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5546
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and BTG2 expression is observed. Does this perturbation lead to a significant difference in BTG2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1463
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CYP3A5 expression is quantified. Does this perturbation result in a significant change in CYP3A5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CYP3A5 expression is quantified. Does this perturbation result in a significant change in CYP3A5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":862
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5943
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of AC006262.5. Does perturbing GLB1L2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of AC006262.5. Does perturbing GLB1L2 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":491
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1934
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CCNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of CCNB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3857
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AC034228.4. Does this perturbation cause a significant change in AC034228.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AC034228.4. Does this perturbation cause a significant change in AC034228.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4294
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Does this perturbation cause a significant change in FZD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of FZD6 is measured. Does this perturbation cause a significant change in FZD6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2990
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1029
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Does this perturbation cause a significant change in DEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of DEK is measured. Does this perturbation cause a significant change in DEK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1670
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and BST2 expression is measured. Determine whether BST2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1939
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TPM4 expression is quantified. Does this perturbation result in a significant change in TPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TMSB4X is perturbed and TPM4 expression is quantified. Does this perturbation result in a significant change in TPM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4512
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of ID3. Does this perturbation cause a significant change in ID3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3484
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and SLC38A2 expression is measured. Determine whether SLC38A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and SLC38A2 expression is measured. Determine whether SLC38A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5699
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of MTURN. Does this perturbation cause a significant change in MTURN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of MTURN. Does this perturbation cause a significant change in MTURN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1884
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Determine whether HMOX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Determine whether HMOX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5976
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MS4A2 expression. Decide whether this perturbation leads to a significant alteration in MS4A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MS4A2 expression. Decide whether this perturbation leads to a significant alteration in MS4A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3938
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of LTC4S. Does perturbing PRTG lead to a significant change in LTC4S expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of LTC4S. Does perturbing PRTG lead to a significant change in LTC4S expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3641
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of FOXF1. Does this perturbation cause a significant change in FOXF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3494
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX3 is perturbed and CHI3L2 expression is measured. Determine whether CHI3L2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":909
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Does this perturbation cause a significant change in N4BP2L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of N4BP2L2 is measured. Does this perturbation cause a significant change in N4BP2L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4220
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and SOX5 expression is measured. Determine whether SOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and SOX5 expression is measured. Determine whether SOX5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2479
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of CALY. Does this perturbation cause a significant change in CALY expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of CALY. Does this perturbation cause a significant change in CALY expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1594
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of UBASH3A. Does perturbing UBASH3A lead to a significant change in UBASH3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4801
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of S100A13. Does this perturbation cause a significant change in S100A13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1824
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in GPR35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LYL1 is associated with a significant change in GPR35 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3925
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in PCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in PCK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5735
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Determine whether HIST1H3H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of HIST1H3H is measured. Determine whether HIST1H3H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5336
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Does this perturbation cause a significant change in TAS1R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Does this perturbation cause a significant change in TAS1R1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":700
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTC-492K19.4. Does this perturbation cause a significant change in CTC-492K19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of CTC-492K19.4. Does this perturbation cause a significant change in CTC-492K19.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1124
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":379
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and C1orf141 expression is observed. Does this perturbation lead to a significant difference in C1orf141 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and C1orf141 expression is observed. Does this perturbation lead to a significant difference in C1orf141 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2333
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-1017G21.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-1017G21.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3827
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Does this perturbation cause a significant change in CCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Does this perturbation cause a significant change in CCS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":130
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of FAM49A. Does this perturbation cause a significant change in FAM49A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of FAM49A. Does this perturbation cause a significant change in FAM49A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":474
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LRRTM4 expression is measured. Determine whether LRRTM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LRRTM4 expression is measured. Determine whether LRRTM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5849
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ABCA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ABCA6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4175
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RP11-285F7.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RP11-285F7.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4905
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CCNB1. Does perturbing C3orf72 lead to a significant change in CCNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of CCNB1. Does perturbing C3orf72 lead to a significant change in CCNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3851
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor PCDHGA3 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor PCDHGA3 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2568
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ABCA13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in ABCA13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2095
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of GPR35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of GPR35 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3927
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor H1FNT expression. Decide whether this perturbation leads to a significant alteration in H1FNT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor H1FNT expression. Decide whether this perturbation leads to a significant alteration in H1FNT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2918
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of PHLDA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1027
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-219B4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-219B4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-219B4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-219B4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1778
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PTRF expression is measured. Determine whether PTRF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and PTRF expression is measured. Determine whether PTRF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1039
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RNF168 expression is observed. Does this perturbation lead to a significant difference in RNF168 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RNF168 expression is observed. Does this perturbation lead to a significant difference in RNF168 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":773
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Determine whether ARPC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Determine whether ARPC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":846
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of TAC3. Does perturbing ARRDC3 lead to a significant change in TAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of TAC3. Does perturbing ARRDC3 lead to a significant change in TAC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3801
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1483
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of LINC01342. Does this perturbation cause a significant change in LINC01342 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of LINC01342. Does this perturbation cause a significant change in LINC01342 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2204
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":926
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and TRPM2 expression is observed. Does this perturbation lead to a significant difference in TRPM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and TRPM2 expression is observed. Does this perturbation lead to a significant difference in TRPM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1423
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Does this perturbation cause a significant change in SEMA3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Does this perturbation cause a significant change in SEMA3B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4240
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and CCNJL expression is observed. Does this perturbation lead to a significant difference in CCNJL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and CCNJL expression is observed. Does this perturbation lead to a significant difference in CCNJL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5123
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Does this perturbation cause a significant change in FADS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4100
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of MBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1007
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Determine whether ST3GAL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Determine whether ST3GAL5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1766
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Determine whether MYO1F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Determine whether MYO1F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1516
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of AC074289.1 is measured. Determine whether AC074289.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4856
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SLC2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SLC2A3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2537
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and MT1E expression is observed. Does this perturbation lead to a significant difference in MT1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and MT1E expression is observed. Does this perturbation lead to a significant difference in MT1E expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":363
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLAUR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of PLAUR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":737
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CKS2 expression is observed. Does this perturbation lead to a significant difference in CKS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and CKS2 expression is observed. Does this perturbation lead to a significant difference in CKS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2073
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor LINC00479 expression. Decide whether this perturbation leads to a significant alteration in LINC00479 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor LINC00479 expression. Decide whether this perturbation leads to a significant alteration in LINC00479 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":418
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor RP11-195B3.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195B3.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor RP11-195B3.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195B3.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2218
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of TRAPPC3L. Does this perturbation cause a significant change in TRAPPC3L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of TRAPPC3L. Does this perturbation cause a significant change in TRAPPC3L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6254
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLA2G1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLA2G1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":755
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CYP1B1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP1B1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and CYP1B1-AS1 expression is observed. Does this perturbation lead to a significant difference in CYP1B1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4313
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CTB-161C1.1 is measured. Determine whether CTB-161C1.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4236
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in LEFTY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in LEFTY2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4945
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Determine whether KCNH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Determine whether KCNH2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3446
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of SLCO6A1. Does this perturbation cause a significant change in SLCO6A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of SLCO6A1. Does this perturbation cause a significant change in SLCO6A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4354
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-345P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and RP11-345P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-345P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2872
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4883
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in LRRC36 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in LRRC36 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":335
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Does this perturbation cause a significant change in CREB3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Does this perturbation cause a significant change in CREB3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5990
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and NBR1 expression is observed. Does this perturbation lead to a significant difference in NBR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4273
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CD52 expression is measured. Determine whether CD52 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6189
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5156
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCM2L expression is observed. Does this perturbation lead to a significant difference in CCM2L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCM2L expression is observed. Does this perturbation lead to a significant difference in CCM2L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2143
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of MSRB1. Does perturbing TP73 lead to a significant change in MSRB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of MSRB1. Does perturbing TP73 lead to a significant change in MSRB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2651
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of TACC1. Does this perturbation cause a significant change in TACC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of TACC1. Does this perturbation cause a significant change in TACC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6004
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":257
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and BAK1 expression is quantified. Does this perturbation result in a significant change in BAK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":622
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of TLN1. Does perturbing MIDN lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of TLN1. Does perturbing MIDN lead to a significant change in TLN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1521
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1270
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of NUMB. Does this perturbation cause a significant change in NUMB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of NUMB. Does this perturbation cause a significant change in NUMB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3264
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TUBA1A expression is quantified. Does this perturbation result in a significant change in TUBA1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and TUBA1A expression is quantified. Does this perturbation result in a significant change in TUBA1A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2712
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":928
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5087
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5110
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":9
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Determine whether CLU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Determine whether CLU shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":16
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in CAPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in CAPG expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4875
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor RP1-261G23.7 expression. Decide whether this perturbation leads to a significant alteration in RP1-261G23.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor RP1-261G23.7 expression. Decide whether this perturbation leads to a significant alteration in RP1-261G23.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1908
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of UCKL1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of UCKL1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5257
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of FNDC3A. Does this perturbation cause a significant change in FNDC3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of FNDC3A. Does this perturbation cause a significant change in FNDC3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4584
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5458
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and SEMA3B expression is measured. Determine whether SEMA3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and SEMA3B expression is measured. Determine whether SEMA3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4249
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-563J2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-563J2.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3815
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Does this perturbation cause a significant change in SPANXN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of SPANXN5 is measured. Does this perturbation cause a significant change in SPANXN5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3460
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of TEX30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of TEX30 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2417
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ARPC3 expression is quantified. Does this perturbation result in a significant change in ARPC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ARPC3 expression is quantified. Does this perturbation result in a significant change in ARPC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":842
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and NCKAP1L expression is quantified. Does this perturbation result in a significant change in NCKAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5922
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in SEMA3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPA is associated with a significant change in SEMA3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4245
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CRYM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2065
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ACTB expression is quantified. Does this perturbation result in a significant change in ACTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ACTB expression is quantified. Does this perturbation result in a significant change in ACTB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2082
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in ID1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4865
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in DEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in DEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1675
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and S100A1 expression is observed. Does this perturbation lead to a significant difference in S100A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and S100A1 expression is observed. Does this perturbation lead to a significant difference in S100A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1753
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and TNFAIP8 expression is quantified. Does this perturbation result in a significant change in TNFAIP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and TNFAIP8 expression is quantified. Does this perturbation result in a significant change in TNFAIP8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2182
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4637
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Does this perturbation cause a significant change in RP11-1017G21.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3820
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":743
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Determine whether RPL17-C18orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of RPL17-C18orf32 is measured. Determine whether RPL17-C18orf32 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5776
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4625
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of SLCO6A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of SLCO6A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4357
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ARL6IP1 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ARL6IP1 expression. Decide whether this perturbation leads to a significant alteration in ARL6IP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2938
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Does this perturbation cause a significant change in CHST15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of CHST15 is measured. Does this perturbation cause a significant change in CHST15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2490
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4214
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in TTC9B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in TTC9B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4495
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Does this perturbation cause a significant change in TACC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Does this perturbation cause a significant change in TACC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6000
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and AC078941.1 expression is quantified. Does this perturbation result in a significant change in AC078941.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and AC078941.1 expression is quantified. Does this perturbation result in a significant change in AC078941.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2012
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4520
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is measured. Determine whether CTD-3131K8.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CTD-3131K8.3 expression is measured. Determine whether CTD-3131K8.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2759
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1386
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4805
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLA2G16 expression is observed. Does this perturbation lead to a significant difference in PLA2G16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and PLA2G16 expression is observed. Does this perturbation lead to a significant difference in PLA2G16 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6153
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5160
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ARRDC3 expression is measured. Determine whether ARRDC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and ARRDC3 expression is measured. Determine whether ARRDC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":239
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1814
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of RP11-195B3.1. Does this perturbation cause a significant change in RP11-195B3.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of RP11-195B3.1. Does this perturbation cause a significant change in RP11-195B3.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2214
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in ESAM expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4155
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of MYLIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of MYLIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1237
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LINC01562 expression is observed. Does this perturbation lead to a significant difference in LINC01562 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LINC01562 expression is observed. Does this perturbation lead to a significant difference in LINC01562 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1313
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ATP10D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ATP10D indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2927
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of CRABP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of CRABP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":287
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of RP11-662J14.2. Does this perturbation cause a significant change in RP11-662J14.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of RP11-662J14.2. Does this perturbation cause a significant change in RP11-662J14.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5244
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3618
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4670
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Determine whether PLEKHO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLEKHO1 is measured. Determine whether PLEKHO1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6126
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of CPVL. Does perturbing BCL2L11 lead to a significant change in CPVL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of CPVL. Does perturbing BCL2L11 lead to a significant change in CPVL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4931
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6052
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1867
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is quantified. Does this perturbation result in a significant change in CTD-3037G24.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is quantified. Does this perturbation result in a significant change in CTD-3037G24.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1432
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Determine whether CITED2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Determine whether CITED2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4286
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ABCB11 expression is quantified. Does this perturbation result in a significant change in ABCB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and ABCB11 expression is quantified. Does this perturbation result in a significant change in ABCB11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1662
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP1-34B20.21. Does perturbing TSC22D1 lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RP1-34B20.21. Does perturbing TSC22D1 lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of CLTA. Does perturbing MAP2K6 lead to a significant change in CLTA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of CLTA. Does perturbing MAP2K6 lead to a significant change in CLTA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3991
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of SOCS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1397
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of CDC45 is measured. Does this perturbation cause a significant change in CDC45 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":120
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and MKNK2 expression is measured. Determine whether MKNK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and MKNK2 expression is measured. Determine whether MKNK2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1629
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Determine whether CRYAB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Determine whether CRYAB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1346
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CDK1. Does this perturbation cause a significant change in CDK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of CDK1. Does this perturbation cause a significant change in CDK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4404
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SLC2A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in SLC2A1-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1995
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Determine whether RP11-505P4.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Determine whether RP11-505P4.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1136
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and SKAP2 expression is observed. Does this perturbation lead to a significant difference in SKAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":963
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP3-510H16.3 expression. Decide whether this perturbation leads to a significant alteration in RP3-510H16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP3-510H16.3 expression. Decide whether this perturbation leads to a significant alteration in RP3-510H16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3838
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6090
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SLC22A25 expression. Decide whether this perturbation leads to a significant alteration in SLC22A25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor SLC22A25 expression. Decide whether this perturbation leads to a significant alteration in SLC22A25 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1838
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of FCER1G is measured. Determine whether FCER1G shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4446
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Determine whether RHOH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of RHOH is measured. Determine whether RHOH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4456
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of SLC4A3. Does perturbing HK2 lead to a significant change in SLC4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of SLC4A3. Does perturbing HK2 lead to a significant change in SLC4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6081
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is measured. Determine whether TMEM35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is measured. Determine whether TMEM35 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5019
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor FEZ1 expression. Decide whether this perturbation leads to a significant alteration in FEZ1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3568
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and SOCS3 expression is quantified. Does this perturbation result in a significant change in SOCS3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2842
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2549
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Determine whether LTC4S shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Determine whether LTC4S shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3646
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Does this perturbation cause a significant change in FAM225B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of FAM225B is measured. Does this perturbation cause a significant change in FAM225B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5230
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and PRSS57 expression is measured. Determine whether PRSS57 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4169
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MS4A3. Does this perturbation cause a significant change in MS4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of MS4A3. Does this perturbation cause a significant change in MS4A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":984
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and BCL2L11 expression is measured. Determine whether BCL2L11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and BCL2L11 expression is measured. Determine whether BCL2L11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4929
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in RP11-290L1.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in RP11-290L1.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2035
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":678
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of BTG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1467
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Does this perturbation cause a significant change in TMEM88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of TMEM88 is measured. Does this perturbation cause a significant change in TMEM88 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5180
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor HSD17B4 expression. Decide whether this perturbation leads to a significant alteration in HSD17B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor HSD17B4 expression. Decide whether this perturbation leads to a significant alteration in HSD17B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":148
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is quantified. Does this perturbation result in a significant change in CACNA1C-AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and CACNA1C-AS2 expression is quantified. Does this perturbation result in a significant change in CACNA1C-AS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":352
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of PRKAG2-AS1. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of PRKAG2-AS1. Does this perturbation cause a significant change in PRKAG2-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3164
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor TAS1R1 expression. Decide whether this perturbation leads to a significant alteration in TAS1R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor TAS1R1 expression. Decide whether this perturbation leads to a significant alteration in TAS1R1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":708
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Does this perturbation cause a significant change in CST9L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of CST9L is measured. Does this perturbation cause a significant change in CST9L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3330
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Determine whether EWSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of EWSAT1 is measured. Determine whether EWSAT1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5316
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of HMGA2. Does perturbing C3orf72 lead to a significant change in HMGA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of HMGA2. Does perturbing C3orf72 lead to a significant change in HMGA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3891
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6248
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and IL1RN expression is quantified. Does this perturbation result in a significant change in IL1RN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and IL1RN expression is quantified. Does this perturbation result in a significant change in IL1RN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2192
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CD37 expression is measured. Determine whether CD37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CD37 expression is measured. Determine whether CD37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3249
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is measured. Determine whether RP11-662J14.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and RP11-662J14.2 expression is measured. Determine whether RP11-662J14.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5249
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4529
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and COL1A1 expression is measured. Determine whether COL1A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and COL1A1 expression is measured. Determine whether COL1A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5059
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BCORL1 is perturbed and the expression of CTD-2311M21.3 is measured. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":400
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1268
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of HBG1. Does this perturbation cause a significant change in HBG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of HBG1. Does this perturbation cause a significant change in HBG1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5384
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Does this perturbation cause a significant change in KRT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of KRT7 is measured. Does this perturbation cause a significant change in KRT7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2790
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3379
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Determine whether RP11-714G18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXO4 is perturbed and the expression of RP11-714G18.1 is measured. Determine whether RP11-714G18.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1856
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP3-510H16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP3-510H16.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3837
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of RP11-202A13.1. Does this perturbation cause a significant change in RP11-202A13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNNM4 and then measure expression of RP11-202A13.1. Does this perturbation cause a significant change in RP11-202A13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4784
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Determine whether PLEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of PLEK is measured. Determine whether PLEK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5096
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and AC078941.1 expression is measured. Determine whether AC078941.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and AC078941.1 expression is measured. Determine whether AC078941.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2019
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of EWSAT1. Does this perturbation cause a significant change in EWSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of EWSAT1. Does this perturbation cause a significant change in EWSAT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5314
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4310
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and CBL expression is observed. Does this perturbation lead to a significant difference in CBL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and CBL expression is observed. Does this perturbation lead to a significant difference in CBL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3143
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and LINC01003 expression is quantified. Does this perturbation result in a significant change in LINC01003 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and LINC01003 expression is quantified. Does this perturbation result in a significant change in LINC01003 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":452
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3323
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of RP11-195B3.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of RP11-195B3.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2217
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RP5-1142A6.2 expression is observed. Does this perturbation lead to a significant difference in RP5-1142A6.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and RP5-1142A6.2 expression is observed. Does this perturbation lead to a significant difference in RP5-1142A6.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4713
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor GYPE expression. Decide whether this perturbation leads to a significant alteration in GYPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3628
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of TUBB3. Does perturbing ZBTB1 lead to a significant change in TUBB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of TUBB3. Does perturbing ZBTB1 lead to a significant change in TUBB3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3591
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of RBM5-AS1. Does perturbing CEBPE lead to a significant change in RBM5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of RBM5-AS1. Does perturbing CEBPE lead to a significant change in RBM5-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":161
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and NCALD expression is quantified. Does this perturbation result in a significant change in NCALD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and NCALD expression is quantified. Does this perturbation result in a significant change in NCALD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4832
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and PCK1 expression is measured. Determine whether PCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and PCK1 expression is measured. Determine whether PCK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5739
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is measured. Determine whether RP11-52L5.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is measured. Determine whether RP11-52L5.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6209
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor CALY expression. Decide whether this perturbation leads to a significant alteration in CALY expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor CALY expression. Decide whether this perturbation leads to a significant alteration in CALY expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1598
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in AC078941.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in AC078941.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2015
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CYP2C18. Does perturbing TBX3 lead to a significant change in CYP2C18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of CYP2C18. Does perturbing TBX3 lead to a significant change in CYP2C18 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":931
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Does this perturbation cause a significant change in TLN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1520
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor HMGA2 expression. Decide whether this perturbation leads to a significant alteration in HMGA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor HMGA2 expression. Decide whether this perturbation leads to a significant alteration in HMGA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3898
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":873
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6058
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Does this perturbation cause a significant change in SLC22A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Does this perturbation cause a significant change in SLC22A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4000
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and TRGVA expression is quantified. Does this perturbation result in a significant change in TRGVA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and TRGVA expression is quantified. Does this perturbation result in a significant change in TRGVA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":952
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3489
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AC007246.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AC007246.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2295
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of SP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of SP6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1707
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4216
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor PCK1 expression. Decide whether this perturbation leads to a significant alteration in PCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor PCK1 expression. Decide whether this perturbation leads to a significant alteration in PCK1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5738
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and SCG5 expression is observed. Does this perturbation lead to a significant difference in SCG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and SCG5 expression is observed. Does this perturbation lead to a significant difference in SCG5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5853
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ATP8A1. Does perturbing FOXF1 lead to a significant change in ATP8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ATP8A1. Does perturbing FOXF1 lead to a significant change in ATP8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3521
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor PERM1 expression. Decide whether this perturbation leads to a significant alteration in PERM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor PERM1 expression. Decide whether this perturbation leads to a significant alteration in PERM1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5488
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and RUNX1 expression is measured. Determine whether RUNX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2789
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and TAS2R9 expression is quantified. Does this perturbation result in a significant change in TAS2R9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and TAS2R9 expression is quantified. Does this perturbation result in a significant change in TAS2R9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":892
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4592
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4682
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of AC144568.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of AC144568.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":597
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTD-3037G24.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3037G24.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor CTD-3037G24.4 expression. Decide whether this perturbation leads to a significant alteration in CTD-3037G24.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1438
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1165
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1749
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of CCRL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":347
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in VMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in VMP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5865
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of WBP2 is measured. Does this perturbation cause a significant change in WBP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1650
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CCDC159. Does this perturbation cause a significant change in CCDC159 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CCDC159. Does this perturbation cause a significant change in CCDC159 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4254
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of RP11-355B11.2. Does perturbing ZNF318 lead to a significant change in RP11-355B11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of RP11-355B11.2. Does perturbing ZNF318 lead to a significant change in RP11-355B11.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1171
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Does this perturbation cause a significant change in RNF182 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Does this perturbation cause a significant change in RNF182 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3950
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ID1. Does perturbing NCL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of ID1. Does perturbing NCL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4861
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in PXK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in PXK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2175
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Does this perturbation cause a significant change in PXK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Does this perturbation cause a significant change in PXK expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2170
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of SLCO6A1. Does perturbing KMT2A lead to a significant change in SLCO6A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of SLCO6A1. Does perturbing KMT2A lead to a significant change in SLCO6A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4351
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and AK8 expression is observed. Does this perturbation lead to a significant difference in AK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and AK8 expression is observed. Does this perturbation lead to a significant difference in AK8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4393
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2486
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and CRYAB expression is measured. Determine whether CRYAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K5 is perturbed and CRYAB expression is measured. Determine whether CRYAB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1349
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in IL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in IL20 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3765
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4045
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of TPH2. Does this perturbation cause a significant change in TPH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of TPH2. Does this perturbation cause a significant change in TPH2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3414
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in EWSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in EWSAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5315
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Determine whether S100A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Determine whether S100A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1916
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of C10orf11. Does perturbing ZC3HAV1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of C10orf11. Does perturbing ZC3HAV1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4961
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of LRRC36 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of LRRC36 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":337
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of DRC1. Does perturbing PTPN13 lead to a significant change in DRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN13 and examine the expression of DRC1. Does perturbing PTPN13 lead to a significant change in DRC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5661
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and IGHEP2 expression is quantified. Does this perturbation result in a significant change in IGHEP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and IGHEP2 expression is quantified. Does this perturbation result in a significant change in IGHEP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3582
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of C17orf64 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1717
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and APOBR expression is measured. Determine whether APOBR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and APOBR expression is measured. Determine whether APOBR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5179
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2307
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of KRT79 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of KRT79 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3887
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1655
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Does this perturbation cause a significant change in CIB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of CIB3 is measured. Does this perturbation cause a significant change in CIB3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5220
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of HEATR9. Does perturbing CDKN1A lead to a significant change in HEATR9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of HEATR9. Does perturbing CDKN1A lead to a significant change in HEATR9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2381
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1266
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and RETN expression is quantified. Does this perturbation result in a significant change in RETN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and RETN expression is quantified. Does this perturbation result in a significant change in RETN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2452
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Does this perturbation cause a significant change in MYB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of MYB is measured. Does this perturbation cause a significant change in MYB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2100
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of CHI3L2. Does this perturbation cause a significant change in CHI3L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":904
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CREB3L2 expression. Decide whether this perturbation leads to a significant alteration in CREB3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor CREB3L2 expression. Decide whether this perturbation leads to a significant alteration in CREB3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5998
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and WBP2 expression is measured. Determine whether WBP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1659
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of CCR10. Does perturbing RHOXF2BB lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of CCR10. Does perturbing RHOXF2BB lead to a significant change in CCR10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1861
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and RNF182 expression is measured. Determine whether RNF182 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and RNF182 expression is measured. Determine whether RNF182 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3959
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor RASGRF2 expression. Decide whether this perturbation leads to a significant alteration in RASGRF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor RASGRF2 expression. Decide whether this perturbation leads to a significant alteration in RASGRF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1548
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and C17orf64 expression is observed. Does this perturbation lead to a significant difference in C17orf64 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1713
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and WDR88 expression is observed. Does this perturbation lead to a significant difference in WDR88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and WDR88 expression is observed. Does this perturbation lead to a significant difference in WDR88 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4723
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor COL18A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in COL18A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor COL18A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in COL18A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":638
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":965
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RUNX3. Does this perturbation cause a significant change in RUNX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RUNX3. Does this perturbation cause a significant change in RUNX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5954
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is quantified. Does this perturbation result in a significant change in TMEM35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and TMEM35 expression is quantified. Does this perturbation result in a significant change in TMEM35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5012
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of PLEK. Does perturbing SPI1 lead to a significant change in PLEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of PLEK. Does perturbing SPI1 lead to a significant change in PLEK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5091
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Does this perturbation cause a significant change in AC016629.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":320
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of CD52 is measured. Determine whether CD52 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":806
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ZNF85 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ZNF85 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":515
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and ARHGDIB expression is observed. Does this perturbation lead to a significant difference in ARHGDIB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4023
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5155
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Does this perturbation cause a significant change in FMNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of FMNL1 is measured. Does this perturbation cause a significant change in FMNL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1690
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and S100A3 expression is quantified. Does this perturbation result in a significant change in S100A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and S100A3 expression is quantified. Does this perturbation result in a significant change in S100A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1912
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Determine whether CRYM shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2066
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of DNAJB1. Does perturbing C3orf72 lead to a significant change in DNAJB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of DNAJB1. Does perturbing C3orf72 lead to a significant change in DNAJB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3861
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Does this perturbation cause a significant change in LBH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of LBH is measured. Does this perturbation cause a significant change in LBH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5930
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Does this perturbation cause a significant change in MBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of MBP is measured. Does this perturbation cause a significant change in MBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1000
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and SH3RF2 expression is quantified. Does this perturbation result in a significant change in SH3RF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and SH3RF2 expression is quantified. Does this perturbation result in a significant change in SH3RF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3232
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Does this perturbation cause a significant change in SLC8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of SLC8A1 is measured. Does this perturbation cause a significant change in SLC8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4550
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CMB9-22P13.1 expression is observed. Does this perturbation lead to a significant difference in CMB9-22P13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CMB9-22P13.1 expression is observed. Does this perturbation lead to a significant difference in CMB9-22P13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5393
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5814
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Determine whether SKAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SKAP1 is measured. Determine whether SKAP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":716
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of HMOX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CITED1, does the expression profile of HMOX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5977
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Does this perturbation cause a significant change in CALY expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of CALY is measured. Does this perturbation cause a significant change in CALY expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1590
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of HIST1H2AC. Does this perturbation cause a significant change in HIST1H2AC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3184
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of MSRB1. Does this perturbation cause a significant change in MSRB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of MSRB1. Does this perturbation cause a significant change in MSRB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2654
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is quantified. Does this perturbation result in a significant change in RP11-635N19.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and RP11-635N19.1 expression is quantified. Does this perturbation result in a significant change in RP11-635N19.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1372
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FAM83A expression is measured. Determine whether FAM83A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and FAM83A expression is measured. Determine whether FAM83A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5629
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in ZFP36L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3675
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor IER3 expression. Decide whether this perturbation leads to a significant alteration in IER3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor IER3 expression. Decide whether this perturbation leads to a significant alteration in IER3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2768
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ADD3. Does this perturbation cause a significant change in ADD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ADD3. Does this perturbation cause a significant change in ADD3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2904
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and UBASH3B expression is measured. Determine whether UBASH3B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1409
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MYOZ3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MYOZ3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3947
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor TNFAIP2 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor TNFAIP2 expression. Decide whether this perturbation leads to a significant alteration in TNFAIP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5208
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Does this perturbation cause a significant change in RP11-442O1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of RP11-442O1.4 is measured. Does this perturbation cause a significant change in RP11-442O1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4660
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in CCNG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in CCNG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4065
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of SCG5. Does perturbing SNAI1 lead to a significant change in SCG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of SCG5. Does perturbing SNAI1 lead to a significant change in SCG5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5851
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and AC020571.3 expression is quantified. Does this perturbation result in a significant change in AC020571.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and AC020571.3 expression is quantified. Does this perturbation result in a significant change in AC020571.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1212
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of MYL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of MYL4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5567
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and STRA6 expression is observed. Does this perturbation lead to a significant difference in STRA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and STRA6 expression is observed. Does this perturbation lead to a significant difference in STRA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":653
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ICAM4 expression is measured. Determine whether ICAM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and ICAM4 expression is measured. Determine whether ICAM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4749
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor IGHEP2 expression. Decide whether this perturbation leads to a significant alteration in IGHEP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor IGHEP2 expression. Decide whether this perturbation leads to a significant alteration in IGHEP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3588
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":676
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Determine whether ANXA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3966
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of WDR88. Does perturbing ARID1A lead to a significant change in WDR88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of WDR88. Does perturbing ARID1A lead to a significant change in WDR88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4721
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-1017G21.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP11-1017G21.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3825
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RP5-1142A6.2. Does perturbing ARID1A lead to a significant change in RP5-1142A6.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RP5-1142A6.2. Does perturbing ARID1A lead to a significant change in RP5-1142A6.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4711
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in BAK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":625
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in RIT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4915
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Determine whether C19orf38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of C19orf38 is measured. Determine whether C19orf38 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4846
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and FAM178B expression is observed. Does this perturbation lead to a significant difference in FAM178B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1743
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4806
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and MSX1 expression is quantified. Does this perturbation result in a significant change in MSX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SGK1 is perturbed and MSX1 expression is quantified. Does this perturbation result in a significant change in MSX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4032
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1152
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TUBB2B is measured. Does this perturbation cause a significant change in TUBB2B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":430
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1466
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of NCF4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":857
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Determine whether PIM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2956
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TMEM55A expression is measured. Determine whether TMEM55A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TMEM55A expression is measured. Determine whether TMEM55A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4609
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of ZC3HAV1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4977
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in C10orf11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3435
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Determine whether FAM118A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Determine whether FAM118A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2666
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor MYL4 expression. Decide whether this perturbation leads to a significant alteration in MYL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor MYL4 expression. Decide whether this perturbation leads to a significant alteration in MYL4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5568
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ATP9A. Does this perturbation cause a significant change in ATP9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ATP9A. Does this perturbation cause a significant change in ATP9A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":534
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SDSL expression. Decide whether this perturbation leads to a significant alteration in SDSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor SDSL expression. Decide whether this perturbation leads to a significant alteration in SDSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2428
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4024
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and SLC7A11 expression is quantified. Does this perturbation result in a significant change in SLC7A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and SLC7A11 expression is quantified. Does this perturbation result in a significant change in SLC7A11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4892
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and PDE1B expression is observed. Does this perturbation lead to a significant difference in PDE1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and PDE1B expression is observed. Does this perturbation lead to a significant difference in PDE1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":33
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Determine whether CCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of CCS is measured. Determine whether CCS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":136
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CIB3 expression is observed. Does this perturbation lead to a significant difference in CIB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CIB3 expression is observed. Does this perturbation lead to a significant difference in CIB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5223
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of SLC43A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of SLC43A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1537
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of COLGALT2 is measured. Determine whether COLGALT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4096
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Does this perturbation cause a significant change in MACF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Does this perturbation cause a significant change in MACF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4730
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Does this perturbation cause a significant change in LINC01420 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01420 is measured. Does this perturbation cause a significant change in LINC01420 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5420
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of CTSW. Does perturbing NIT1 lead to a significant change in CTSW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of CTSW. Does perturbing NIT1 lead to a significant change in CTSW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5361
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Determine whether DNAJB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C3orf72 is perturbed and the expression of DNAJB1 is measured. Determine whether DNAJB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3866
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of CISH. Does this perturbation cause a significant change in CISH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3604
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SLC2A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in SLC2A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SLC2A1-AS1 expression. Decide whether this perturbation leads to a significant alteration in SLC2A1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1998
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor MYO1F expression. Decide whether this perturbation leads to a significant alteration in MYO1F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor MYO1F expression. Decide whether this perturbation leads to a significant alteration in MYO1F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1518
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2857
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ALAS2. Does perturbing ARRDC3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARRDC3 and examine the expression of ALAS2. Does perturbing ARRDC3 lead to a significant change in ALAS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3781
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and TAC3 expression is quantified. Does this perturbation result in a significant change in TAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and TAC3 expression is quantified. Does this perturbation result in a significant change in TAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3802
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in RP11-180M15.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in RP11-180M15.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4435
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and KIAA2012 expression is quantified. Does this perturbation result in a significant change in KIAA2012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and KIAA2012 expression is quantified. Does this perturbation result in a significant change in KIAA2012 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":112
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Does this perturbation cause a significant change in INHBE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Does this perturbation cause a significant change in INHBE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5780
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and MME expression is measured. Determine whether MME exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and MME expression is measured. Determine whether MME exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6269
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CHP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CHP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5467
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLA2G16 expression. Decide whether this perturbation leads to a significant alteration in PLA2G16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLA2G16 expression. Decide whether this perturbation leads to a significant alteration in PLA2G16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6158
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Does this perturbation cause a significant change in SLC4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Does this perturbation cause a significant change in SLC4A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6080
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and VGF expression is observed. Does this perturbation lead to a significant difference in VGF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ELMSAN1 is perturbed and VGF expression is observed. Does this perturbation lead to a significant difference in VGF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":263
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of ZFP36L2 is measured. Determine whether ZFP36L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3676
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor S100A1 expression. Decide whether this perturbation leads to a significant alteration in S100A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor S100A1 expression. Decide whether this perturbation leads to a significant alteration in S100A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1758
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and ACE expression is measured. Determine whether ACE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3659
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Determine whether CYP3A5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CYP3A5 is measured. Determine whether CYP3A5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":866
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ATP8B4 expression is observed. Does this perturbation lead to a significant difference in ATP8B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and ATP8B4 expression is observed. Does this perturbation lead to a significant difference in ATP8B4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1553
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and LEFTY2 expression is observed. Does this perturbation lead to a significant difference in LEFTY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and LEFTY2 expression is observed. Does this perturbation lead to a significant difference in LEFTY2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4943
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Determine whether SSTR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Determine whether SSTR3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3176
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of ZMAT3. Does this perturbation cause a significant change in ZMAT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5134
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5925
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LST1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3325
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and CLTA expression is measured. Determine whether CLTA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and CLTA expression is measured. Determine whether CLTA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3999
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MS4A3 expression is observed. Does this perturbation lead to a significant difference in MS4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MS4A3 expression is observed. Does this perturbation lead to a significant difference in MS4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":983
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4628
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Does this perturbation cause a significant change in CEBPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of CEBPA is measured. Does this perturbation cause a significant change in CEBPA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1630
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of RP1-34B20.21. Does perturbing KIF18B lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of RP1-34B20.21. Does perturbing KIF18B lead to a significant change in RP1-34B20.21 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6111
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of CLU. Does this perturbation cause a significant change in CLU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of CLU. Does this perturbation cause a significant change in CLU expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":14
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Determine whether RP11-83A24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Determine whether RP11-83A24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":526
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of UBASH3B. Does perturbing UBASH3B lead to a significant change in UBASH3B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1401
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Determine whether RNF182 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of RNF182 is measured. Determine whether RNF182 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3956
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXL2 is perturbed and SOCS1 expression is measured. Determine whether SOCS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4089
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and N4BP2L2 expression is quantified. Does this perturbation result in a significant change in N4BP2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and N4BP2L2 expression is quantified. Does this perturbation result in a significant change in N4BP2L2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4222
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2285
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of RNF213. Does this perturbation cause a significant change in RNF213 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4474
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of MYC. Does perturbing IKZF3 lead to a significant change in MYC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of MYC. Does perturbing IKZF3 lead to a significant change in MYC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3021
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and PSMB8 expression is measured. Determine whether PSMB8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and PSMB8 expression is measured. Determine whether PSMB8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":109
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Determine whether SOCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Determine whether SOCS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":696
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of CEBPA. Does this perturbation cause a significant change in CEBPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBFA2T3 and then measure expression of CEBPA. Does this perturbation cause a significant change in CEBPA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1634
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ARPC3 expression is observed. Does this perturbation lead to a significant difference in ARPC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and ARPC3 expression is observed. Does this perturbation lead to a significant difference in ARPC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":843
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ZNF467. Does perturbing SET lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ZNF467. Does perturbing SET lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":871
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and AFMID expression is quantified. Does this perturbation result in a significant change in AFMID expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5502
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of IL1RN. Does this perturbation cause a significant change in IL1RN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CELF2 and then measure expression of IL1RN. Does this perturbation cause a significant change in IL1RN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2194
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RUNX3. Does perturbing CITED1 lead to a significant change in RUNX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of RUNX3. Does perturbing CITED1 lead to a significant change in RUNX3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5951
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ATP9A expression is observed. Does this perturbation lead to a significant difference in ATP9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ATP9A expression is observed. Does this perturbation lead to a significant difference in ATP9A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":533
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor TM4SF1-AS1 expression. Decide whether this perturbation leads to a significant alteration in TM4SF1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor TM4SF1-AS1 expression. Decide whether this perturbation leads to a significant alteration in TM4SF1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3758
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of TRAPPC3L. Does perturbing CDKN1C lead to a significant change in TRAPPC3L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of TRAPPC3L. Does perturbing CDKN1C lead to a significant change in TRAPPC3L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6251
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is quantified. Does this perturbation result in a significant change in RP11-286H15.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is quantified. Does this perturbation result in a significant change in RP11-286H15.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2512
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Does this perturbation cause a significant change in COL1A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Does this perturbation cause a significant change in COL1A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5050
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4620
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Determine whether NBR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4276
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Does this perturbation cause a significant change in AC144568.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Does this perturbation cause a significant change in AC144568.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":590
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ACTB expression is observed. Does this perturbation lead to a significant difference in ACTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and ACTB expression is observed. Does this perturbation lead to a significant difference in ACTB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2083
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ANXA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in ANXA3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3965
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of FCGR2A is measured. Does this perturbation cause a significant change in FCGR2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":540
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and C19orf38 expression is observed. Does this perturbation lead to a significant difference in C19orf38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and C19orf38 expression is observed. Does this perturbation lead to a significant difference in C19orf38 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4843
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Does this perturbation cause a significant change in AC007193.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of AC007193.6 is measured. Does this perturbation cause a significant change in AC007193.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2630
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ZC3HAV1. Does perturbing ZC3HAV1 lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of ZC3HAV1. Does perturbing ZC3HAV1 lead to a significant change in ZC3HAV1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4971
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4164
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of RPS6KA2. Does perturbing DLX2 lead to a significant change in RPS6KA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of RPS6KA2. Does perturbing DLX2 lead to a significant change in RPS6KA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1601
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of TUBB3. Does this perturbation cause a significant change in TUBB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of TUBB3. Does this perturbation cause a significant change in TUBB3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3594
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of SPARC. Does perturbing JUN lead to a significant change in SPARC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of SPARC. Does perturbing JUN lead to a significant change in SPARC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5521
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1162
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of DST indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2347
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of TXNIP. Does perturbing ARID1A lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of TXNIP. Does perturbing ARID1A lead to a significant change in TXNIP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4691
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PCDHGA6 expression is observed. Does this perturbation lead to a significant difference in PCDHGA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and PCDHGA6 expression is observed. Does this perturbation lead to a significant difference in PCDHGA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1303
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and CNN2 expression is measured. Determine whether CNN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and CNN2 expression is measured. Determine whether CNN2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4709
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of FEZ1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4777
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4152
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in SLC7A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NCL is associated with a significant change in SLC7A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4895
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3874
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of RP11-662J14.2. Does perturbing CEBPB lead to a significant change in RP11-662J14.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of RP11-662J14.2. Does perturbing CEBPB lead to a significant change in RP11-662J14.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5241
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of BST2. Does perturbing IKZF3 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of BST2. Does perturbing IKZF3 lead to a significant change in BST2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3011
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CENPE expression. Decide whether this perturbation leads to a significant alteration in CENPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CENPE expression. Decide whether this perturbation leads to a significant alteration in CENPE expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6228
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Does this perturbation cause a significant change in NCALD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Does this perturbation cause a significant change in NCALD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4830
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3456
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIPK1-AS1 expression is observed. Does this perturbation lead to a significant difference in HIPK1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIPK1-AS1 expression is observed. Does this perturbation lead to a significant difference in HIPK1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3223
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor CRABP2 expression. Decide whether this perturbation leads to a significant alteration in CRABP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor CRABP2 expression. Decide whether this perturbation leads to a significant alteration in CRABP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":288
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of CCNJL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of CCNJL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5127
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD24. Does perturbing BPGM lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of CD24. Does perturbing BPGM lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3731
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of MSX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of MSX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4037
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and FAM19A2 expression is observed. Does this perturbation lead to a significant difference in FAM19A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and FAM19A2 expression is observed. Does this perturbation lead to a significant difference in FAM19A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3363
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ZNF677 expression. Decide whether this perturbation leads to a significant alteration in ZNF677 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor ZNF677 expression. Decide whether this perturbation leads to a significant alteration in ZNF677 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3098
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HHEX expression is observed. Does this perturbation lead to a significant difference in HHEX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and HHEX expression is observed. Does this perturbation lead to a significant difference in HHEX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3383
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3780
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Does this perturbation cause a significant change in VMP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Does this perturbation cause a significant change in VMP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5860
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TMEM55A expression. Decide whether this perturbation leads to a significant alteration in TMEM55A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TMEM55A expression. Decide whether this perturbation leads to a significant alteration in TMEM55A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4608
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of LEFTY2. Does perturbing BCL2L11 lead to a significant change in LEFTY2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of LEFTY2. Does perturbing BCL2L11 lead to a significant change in LEFTY2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4941
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3078
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Determine whether RP11-219B4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-219B4.7 is measured. Determine whether RP11-219B4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1776
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and C17orf64 expression is quantified. Does this perturbation result in a significant change in C17orf64 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1712
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor PHACTR1 expression. Decide whether this perturbation leads to a significant alteration in PHACTR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor PHACTR1 expression. Decide whether this perturbation leads to a significant alteration in PHACTR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4388
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LST1. Does perturbing FOXA3 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of LST1. Does perturbing FOXA3 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3321
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TM6SF2 expression is quantified. Does this perturbation result in a significant change in TM6SF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4372
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and AMHR2 expression is measured. Determine whether AMHR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6109
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CPXM1. Does perturbing BCORL1 lead to a significant change in CPXM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of CPXM1. Does perturbing BCORL1 lead to a significant change in CPXM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":381
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RNF168 expression is quantified. Does this perturbation result in a significant change in RNF168 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RNF168 expression is quantified. Does this perturbation result in a significant change in RNF168 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":772
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in ZNF431 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5835
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":553
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2946
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCDC148 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of CCDC148 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2137
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5636
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SOCS2. Does perturbing FEV lead to a significant change in SOCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SOCS2. Does perturbing FEV lead to a significant change in SOCS2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":691
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RGPD5 expression is quantified. Does this perturbation result in a significant change in RGPD5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and RGPD5 expression is quantified. Does this perturbation result in a significant change in RGPD5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5962
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in MT1E expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":365
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3919
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Determine whether ACTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Determine whether ACTC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5376
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6116
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ABCB11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBFA2T3 is associated with a significant change in ABCB11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1665
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ATP8B4 expression is measured. Determine whether ATP8B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and ATP8B4 expression is measured. Determine whether ATP8B4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1559
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Determine whether S100A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of S100A1 is measured. Determine whether S100A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1756
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of GRN is measured. Does this perturbation cause a significant change in GRN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5880
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and MARCKS expression is measured. Determine whether MARCKS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and MARCKS expression is measured. Determine whether MARCKS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4999
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Does this perturbation cause a significant change in CD47 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ETS2 is perturbed and the expression of CD47 is measured. Does this perturbation cause a significant change in CD47 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":780
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and NPW expression is quantified. Does this perturbation result in a significant change in NPW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and NPW expression is quantified. Does this perturbation result in a significant change in NPW expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6042
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and IGFL2 expression is observed. Does this perturbation lead to a significant difference in IGFL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and IGFL2 expression is observed. Does this perturbation lead to a significant difference in IGFL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5493
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3066
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Determine whether UNC5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Determine whether UNC5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3256
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of HCAR2. Does perturbing STIL lead to a significant change in HCAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of HCAR2. Does perturbing STIL lead to a significant change in HCAR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5191
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and INHBE expression is measured. Determine whether INHBE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and INHBE expression is measured. Determine whether INHBE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5789
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD9 expression is measured. Determine whether CD9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3749
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3063
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of AFMID indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2967
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1642
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1026
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Determine whether ATP8B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Determine whether ATP8B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1556
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4763
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in VGF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in VGF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":265
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of CRYM is measured. Does this perturbation cause a significant change in CRYM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2060
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of EMP3. Does this perturbation cause a significant change in EMP3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3034
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Does this perturbation cause a significant change in PRKCB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3790
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor HOGA1 expression. Decide whether this perturbation leads to a significant alteration in HOGA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor HOGA1 expression. Decide whether this perturbation leads to a significant alteration in HOGA1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2868
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and PIM2 expression is measured. Determine whether PIM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2959
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of HBE1. Does this perturbation cause a significant change in HBE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of HBE1. Does this perturbation cause a significant change in HBE1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":444
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-219B4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-219B4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1775
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and CCR10 expression is observed. Does this perturbation lead to a significant difference in CCR10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1863
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ACTB expression is measured. Determine whether ACTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ACTB expression is measured. Determine whether ACTB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2089
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor DPYSL2 expression. Decide whether this perturbation leads to a significant alteration in DPYSL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor DPYSL2 expression. Decide whether this perturbation leads to a significant alteration in DPYSL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5808
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2057
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ACP5 expression is quantified. Does this perturbation result in a significant change in ACP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and ACP5 expression is quantified. Does this perturbation result in a significant change in ACP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1202
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SOCS2 expression. Decide whether this perturbation leads to a significant alteration in SOCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SOCS2 expression. Decide whether this perturbation leads to a significant alteration in SOCS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":698
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TRIM22. Does perturbing KIF2C lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of TRIM22. Does perturbing KIF2C lead to a significant change in TRIM22 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4591
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor SOCS3 expression. Decide whether this perturbation leads to a significant alteration in SOCS3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2848
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in SP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in SP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1705
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and DLX4 expression is quantified. Does this perturbation result in a significant change in DLX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and DLX4 expression is quantified. Does this perturbation result in a significant change in DLX4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6162
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Does this perturbation cause a significant change in RP11-505P4.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of RP11-505P4.6 is measured. Does this perturbation cause a significant change in RP11-505P4.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1130
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and BST2 expression is quantified. Does this perturbation result in a significant change in BST2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1932
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in FAM101B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":305
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and CTSW expression is measured. Determine whether CTSW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and CTSW expression is measured. Determine whether CTSW exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5369
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Determine whether PCDHGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Determine whether PCDHGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2566
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in RASGRF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in RASGRF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1545
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and AC006262.5 expression is measured. Determine whether AC006262.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4579
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of FAM19A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of FAM19A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3367
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PTRF expression is observed. Does this perturbation lead to a significant difference in PTRF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PTRF expression is observed. Does this perturbation lead to a significant difference in PTRF expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1033
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in COL1A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in COL1A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5055
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Does this perturbation cause a significant change in ST3GAL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of ST3GAL5 is measured. Does this perturbation cause a significant change in ST3GAL5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1760
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of SAT2. Does perturbing HOXB9 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of SAT2. Does perturbing HOXB9 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3071
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of DCAF13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of DCAF13 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3547
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in CRYAB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in CRYAB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1345
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of RP11-286H15.1. Does perturbing TBX2 lead to a significant change in RP11-286H15.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of RP11-286H15.1. Does perturbing TBX2 lead to a significant change in RP11-286H15.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2511
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of SLC22A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of SLC22A11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4307
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of CISH is measured. Does this perturbation cause a significant change in CISH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3600
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ARRDC3 expression is observed. Does this perturbation lead to a significant difference in ARRDC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and ARRDC3 expression is observed. Does this perturbation lead to a significant difference in ARRDC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":233
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor CTD-2616J11.16 expression. Decide whether this perturbation leads to a significant alteration in CTD-2616J11.16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor CTD-2616J11.16 expression. Decide whether this perturbation leads to a significant alteration in CTD-2616J11.16 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1198
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CRYM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2067
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CD46. Does this perturbation cause a significant change in CD46 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4204
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4969
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of C17orf64. Does this perturbation cause a significant change in C17orf64 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1714
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of PHACTR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of PHACTR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4387
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is measured. Determine whether TM4SF1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is measured. Determine whether TM4SF1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3759
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor NUMB expression. Decide whether this perturbation leads to a significant alteration in NUMB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor NUMB expression. Decide whether this perturbation leads to a significant alteration in NUMB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3268
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and RP11-1085N6.3 expression is observed. Does this perturbation lead to a significant difference in RP11-1085N6.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and RP11-1085N6.3 expression is observed. Does this perturbation lead to a significant difference in RP11-1085N6.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3403
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PAQR7 expression. Decide whether this perturbation leads to a significant alteration in PAQR7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1188
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLEKHO1 expression is quantified. Does this perturbation result in a significant change in PLEKHO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLEKHO1 expression is quantified. Does this perturbation result in a significant change in PLEKHO1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6122
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of FOXL2. Does perturbing PLK4 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of FOXL2. Does perturbing PLK4 lead to a significant change in FOXL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3681
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and MFSD2A expression is quantified. Does this perturbation result in a significant change in MFSD2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3872
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and PPP4R4 expression is measured. Determine whether PPP4R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and PPP4R4 expression is measured. Determine whether PPP4R4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4619
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of PROX1. Does perturbing SGK1 lead to a significant change in PROX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of PROX1. Does perturbing SGK1 lead to a significant change in PROX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4051
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3508
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TPM4 expression is measured. Determine whether TPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TPM4 expression is measured. Determine whether TPM4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4519
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2520
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in LEFTY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXA13 is associated with a significant change in LEFTY1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5915
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ARRDC3 expression. Decide whether this perturbation leads to a significant alteration in ARRDC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor ARRDC3 expression. Decide whether this perturbation leads to a significant alteration in ARRDC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":238
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ATP8A1 expression. Decide whether this perturbation leads to a significant alteration in ATP8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor ATP8A1 expression. Decide whether this perturbation leads to a significant alteration in ATP8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3528
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":84
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and BTG2 expression is quantified. Does this perturbation result in a significant change in BTG2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2042
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":434
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MEIS1 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":424
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and MAP7D1 expression is observed. Does this perturbation lead to a significant difference in MAP7D1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2723
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is quantified. Does this perturbation result in a significant change in CTC-490E21.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and CTC-490E21.10 expression is quantified. Does this perturbation result in a significant change in CTC-490E21.10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":572
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Does this perturbation cause a significant change in ABCA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of ABCA6 is measured. Does this perturbation cause a significant change in ABCA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4170
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3372
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and DYNLL1 expression is measured. Determine whether DYNLL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOSB is perturbed and DYNLL1 expression is measured. Determine whether DYNLL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2819
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and KIAA2012 expression is measured. Determine whether KIAA2012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and KIAA2012 expression is measured. Determine whether KIAA2012 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":119
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ORAI3 expression is observed. Does this perturbation lead to a significant difference in ORAI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and ORAI3 expression is observed. Does this perturbation lead to a significant difference in ORAI3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1943
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of CCNB2. Does this perturbation cause a significant change in CCNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of CCNB2. Does this perturbation cause a significant change in CCNB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4334
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of TFAP2A. Does this perturbation cause a significant change in TFAP2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of TFAP2A. Does this perturbation cause a significant change in TFAP2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2314
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Does this perturbation cause a significant change in TMEM55A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TMEM55A is measured. Does this perturbation cause a significant change in TMEM55A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4600
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and PHGDH expression is measured. Determine whether PHGDH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4509
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Does this perturbation cause a significant change in RP11-286H15.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Does this perturbation cause a significant change in RP11-286H15.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2510
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of SPARC. Does this perturbation cause a significant change in SPARC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of SPARC. Does this perturbation cause a significant change in SPARC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5524
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Does this perturbation cause a significant change in RABGAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":480
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C6orf1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C6orf1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1877
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ARPC3. Does perturbing SET lead to a significant change in ARPC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of ARPC3. Does perturbing SET lead to a significant change in ARPC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":841
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-219B4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-219B4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-219B4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-219B4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1773
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of RGS16. Does perturbing DUSP9 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of RGS16. Does perturbing DUSP9 lead to a significant change in RGS16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":211
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZC3HAV1 is associated with a significant change in ZC3HAV1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4975
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CTD-2311M21.3. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of CTD-2311M21.3. Does this perturbation cause a significant change in CTD-2311M21.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":404
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CTD-2311M21.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CTD-2311M21.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":407
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Does this perturbation cause a significant change in PDE1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Does this perturbation cause a significant change in PDE1B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":30
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and GCM2 expression is quantified. Does this perturbation result in a significant change in GCM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and GCM2 expression is quantified. Does this perturbation result in a significant change in GCM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1352
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and RP11-91A18.4 expression is measured. Determine whether RP11-91A18.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and RP11-91A18.4 expression is measured. Determine whether RP11-91A18.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2699
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and ZNF467 expression is observed. Does this perturbation lead to a significant difference in ZNF467 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6133
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Does this perturbation cause a significant change in FILIP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2260
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4527
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in NCKAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3085
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in PRKCB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3795
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of S100A1. Does this perturbation cause a significant change in S100A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of S100A1. Does this perturbation cause a significant change in S100A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1754
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of UBASH3B. Does this perturbation cause a significant change in UBASH3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1404
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and TRAPPC3L expression is quantified. Does this perturbation result in a significant change in TRAPPC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and TRAPPC3L expression is quantified. Does this perturbation result in a significant change in TRAPPC3L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6252
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CTD-2378E12.1. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CTD-2378E12.1. Does this perturbation cause a significant change in CTD-2378E12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6274
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LRP10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in LRP10 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3315
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of RP11-369K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of RP11-369K17.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5477
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of MACF1. Does this perturbation cause a significant change in MACF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of MACF1. Does this perturbation cause a significant change in MACF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4734
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":808
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ARHGEF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in ARHGEF6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2115
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LINC01562. Does this perturbation cause a significant change in LINC01562 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LINC01562. Does this perturbation cause a significant change in LINC01562 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1314
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in LHX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":615
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of UBE2H is measured. Determine whether UBE2H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2366
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor TFRC expression. Decide whether this perturbation leads to a significant alteration in TFRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor TFRC expression. Decide whether this perturbation leads to a significant alteration in TFRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1228
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is quantified. Does this perturbation result in a significant change in RP11-202A13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and RP11-202A13.1 expression is quantified. Does this perturbation result in a significant change in RP11-202A13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4782
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of TCAF2. Does perturbing IRF1 lead to a significant change in TCAF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of TCAF2. Does perturbing IRF1 lead to a significant change in TCAF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2971
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Does this perturbation cause a significant change in LST1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5260
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and LPAR2 expression is observed. Does this perturbation lead to a significant difference in LPAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and LPAR2 expression is observed. Does this perturbation lead to a significant difference in LPAR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3103
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of NUDC. Does this perturbation cause a significant change in NUDC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of NUDC. Does this perturbation cause a significant change in NUDC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2154
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Does this perturbation cause a significant change in RELB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of RELB is measured. Does this perturbation cause a significant change in RELB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5650
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Does this perturbation cause a significant change in TNFAIP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Does this perturbation cause a significant change in TNFAIP8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2180
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1389
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and LGALS12 expression is observed. Does this perturbation lead to a significant difference in LGALS12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DUSP9 is perturbed and LGALS12 expression is observed. Does this perturbation lead to a significant difference in LGALS12 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":183
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ARMCX3 expression. Decide whether this perturbation leads to a significant alteration in ARMCX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ARMCX3 expression. Decide whether this perturbation leads to a significant alteration in ARMCX3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3978
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of LST1. Does perturbing ATL1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of LST1. Does perturbing ATL1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5261
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC6A9 and then measure expression of RCSD1. Does this perturbation cause a significant change in RCSD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1444
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Does this perturbation cause a significant change in AMPH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Does this perturbation cause a significant change in AMPH expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6010
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ATP8B4. Does this perturbation cause a significant change in ATP8B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of ATP8B4. Does this perturbation cause a significant change in ATP8B4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1554
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of AIF1 is measured. Does this perturbation cause a significant change in AIF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6050
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of SLC22A11. Does this perturbation cause a significant change in SLC22A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of SLC22A11. Does this perturbation cause a significant change in SLC22A11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4304
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of SH3BGRL is measured. Determine whether SH3BGRL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":396
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4475
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2040
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and TNFAIP2 expression is measured. Determine whether TNFAIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and TNFAIP2 expression is measured. Determine whether TNFAIP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5209
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and SSTR3 expression is measured. Determine whether SSTR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and SSTR3 expression is measured. Determine whether SSTR3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3179
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of PYROXD2. Does perturbing MAP2K3 lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of PYROXD2. Does perturbing MAP2K3 lead to a significant change in PYROXD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2221
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and PHLDA2 expression is observed. Does this perturbation lead to a significant difference in PHLDA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1023
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in S100A13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1825
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and PNMT expression is measured. Determine whether PNMT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3669
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor CRYAB expression. Decide whether this perturbation leads to a significant alteration in CRYAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor CRYAB expression. Decide whether this perturbation leads to a significant alteration in CRYAB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1348
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Does this perturbation cause a significant change in MTURN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1880
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-1017G21.6 expression is observed. Does this perturbation lead to a significant difference in RP11-1017G21.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP11-1017G21.6 expression is observed. Does this perturbation lead to a significant difference in RP11-1017G21.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3823
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of SH3RF2. Does this perturbation cause a significant change in SH3RF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CKS1B and then measure expression of SH3RF2. Does this perturbation cause a significant change in SH3RF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3234
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of WBP2 is measured. Determine whether WBP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5166
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ARL6IP1 expression is observed. Does this perturbation lead to a significant difference in ARL6IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ARL6IP1 expression is observed. Does this perturbation lead to a significant difference in ARL6IP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2933
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and FZD6 expression is measured. Determine whether FZD6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and FZD6 expression is measured. Determine whether FZD6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2999
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TRIM31 expression is observed. Does this perturbation lead to a significant difference in TRIM31 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and TRIM31 expression is observed. Does this perturbation lead to a significant difference in TRIM31 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":463
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor RP11-38J22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-38J22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor RP11-38J22.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-38J22.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6078
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Determine whether ANXA5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Determine whether ANXA5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2856
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Does this perturbation cause a significant change in RP11-76E17.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of RP11-76E17.2 is measured. Does this perturbation cause a significant change in RP11-76E17.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3340
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor MFSD2A expression. Decide whether this perturbation leads to a significant alteration in MFSD2A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6098
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in FEZ1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4775
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Determine whether WDR88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of WDR88 is measured. Determine whether WDR88 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4726
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in PPP4R4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in PPP4R4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4615
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor FAM225B expression. Decide whether this perturbation leads to a significant alteration in FAM225B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor FAM225B expression. Decide whether this perturbation leads to a significant alteration in FAM225B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5238
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and PLEK expression is quantified. Does this perturbation result in a significant change in PLEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and PLEK expression is quantified. Does this perturbation result in a significant change in PLEK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5092
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of MMP19. Does this perturbation cause a significant change in MMP19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of MMP19. Does this perturbation cause a significant change in MMP19 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":944
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":966
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6132
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CTD-2378E12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2378E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1C and monitor CTD-2378E12.1 expression. Decide whether this perturbation leads to a significant alteration in CTD-2378E12.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6278
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Does this perturbation cause a significant change in PLAUR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of PLAUR is measured. Does this perturbation cause a significant change in PLAUR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":730
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of HEMGN. Does perturbing LYL1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of HEMGN. Does perturbing LYL1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3911
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor SPANXD expression. Decide whether this perturbation leads to a significant alteration in SPANXD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor SPANXD expression. Decide whether this perturbation leads to a significant alteration in SPANXD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4198
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Does this perturbation cause a significant change in ADD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of ADD3 is measured. Does this perturbation cause a significant change in ADD3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2900
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Determine whether FABP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of FABP3 is measured. Determine whether FABP3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3726
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MYOZ3 expression is observed. Does this perturbation lead to a significant difference in MYOZ3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MYOZ3 expression is observed. Does this perturbation lead to a significant difference in MYOZ3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3943
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4864
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ATP9A expression. Decide whether this perturbation leads to a significant alteration in ATP9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor ATP9A expression. Decide whether this perturbation leads to a significant alteration in ATP9A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":538
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3300
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of PCDHGA3. Does this perturbation cause a significant change in PCDHGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of PCDHGA3. Does this perturbation cause a significant change in PCDHGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2564
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Does this perturbation cause a significant change in IL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of IL20 is measured. Does this perturbation cause a significant change in IL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3760
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2605
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in RP11-968A15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in RP11-968A15.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":835
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RPL17-C18orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in RPL17-C18orf32 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5775
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Does this perturbation cause a significant change in LTC4S expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of LTC4S is measured. Does this perturbation cause a significant change in LTC4S expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3640
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":724
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Does this perturbation cause a significant change in HIST1H4H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Does this perturbation cause a significant change in HIST1H4H expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4340
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ACTC1. Does this perturbation cause a significant change in ACTC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of ACTC1. Does this perturbation cause a significant change in ACTC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5374
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Does this perturbation cause a significant change in RP11-537H15.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Does this perturbation cause a significant change in RP11-537H15.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2270
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of AIF1 is measured. Determine whether AIF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1166
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5408
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2468
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PCDHGA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of PCDHGA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1307
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Does this perturbation cause a significant change in RP4-550H1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of RP4-550H1.4 is measured. Does this perturbation cause a significant change in RP4-550H1.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5790
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ATP8B4. Does perturbing MIDN lead to a significant change in ATP8B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of ATP8B4. Does perturbing MIDN lead to a significant change in ATP8B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1551
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor FAM19A2 expression. Decide whether this perturbation leads to a significant alteration in FAM19A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor FAM19A2 expression. Decide whether this perturbation leads to a significant alteration in FAM19A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3368
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of FEZ1. Does perturbing CNNM4 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of FEZ1. Does perturbing CNNM4 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4771
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP11-345P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-345P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAPK1 and monitor RP11-345P4.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-345P4.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2878
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and DLX4 expression is observed. Does this perturbation lead to a significant difference in DLX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and DLX4 expression is observed. Does this perturbation lead to a significant difference in DLX4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6163
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5046
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZC3HAV1 is measured. Does this perturbation cause a significant change in ZC3HAV1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3190
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and AIF1 expression is observed. Does this perturbation lead to a significant difference in AIF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2283
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5986
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4627
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Does this perturbation cause a significant change in RP11-6D1.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Does this perturbation cause a significant change in RP11-6D1.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4010
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CDC45. Does perturbing CEBPE lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of CDC45. Does perturbing CEBPE lead to a significant change in CDC45 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":121
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RP11-285F7.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RP11-285F7.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4907
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of KIAA2012. Does perturbing MAML2 lead to a significant change in KIAA2012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of KIAA2012. Does perturbing MAML2 lead to a significant change in KIAA2012 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":111
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-505P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IER5L is perturbed and RP11-505P4.7 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2553
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor RP1-102K2.6 expression. Decide whether this perturbation leads to a significant alteration in RP1-102K2.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1018
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor CST9L expression. Decide whether this perturbation leads to a significant alteration in CST9L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor CST9L expression. Decide whether this perturbation leads to a significant alteration in CST9L expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3338
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Does this perturbation cause a significant change in EGOT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of EGOT is measured. Does this perturbation cause a significant change in EGOT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5670
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and SLC4A3 expression is quantified. Does this perturbation result in a significant change in SLC4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and SLC4A3 expression is quantified. Does this perturbation result in a significant change in SLC4A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6082
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Determine whether RP3-510H16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP3-510H16.3 is measured. Determine whether RP3-510H16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3836
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor DSC1 expression. Decide whether this perturbation leads to a significant alteration in DSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor DSC1 expression. Decide whether this perturbation leads to a significant alteration in DSC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1298
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Determine whether SLC22A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of SLC22A13 is measured. Determine whether SLC22A13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4006
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor S100A13 expression. Decide whether this perturbation leads to a significant alteration in S100A13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1828
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-563J2.3. Does this perturbation cause a significant change in RP11-563J2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP11-563J2.3. Does this perturbation cause a significant change in RP11-563J2.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3814
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1189
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in FCER1G expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4445
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of FMNL1. Does this perturbation cause a significant change in FMNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of FMNL1. Does this perturbation cause a significant change in FMNL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1694
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and TLCD2 expression is measured. Determine whether TLCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and TLCD2 expression is measured. Determine whether TLCD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5559
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5744
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and MFGE8 expression is observed. Does this perturbation lead to a significant difference in MFGE8 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2483
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of DYNLT3. Does this perturbation cause a significant change in DYNLT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of DYNLT3. Does this perturbation cause a significant change in DYNLT3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2674
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CARMN expression is measured. Determine whether CARMN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and CARMN expression is measured. Determine whether CARMN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3279
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Determine whether RP11-537H15.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of RP11-537H15.3 is measured. Determine whether RP11-537H15.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2276
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and ESAM expression is quantified. Does this perturbation result in a significant change in ESAM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5272
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of SP6. Does this perturbation cause a significant change in SP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of SP6. Does this perturbation cause a significant change in SP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1704
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor FAM49A expression. Decide whether this perturbation leads to a significant alteration in FAM49A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor FAM49A expression. Decide whether this perturbation leads to a significant alteration in FAM49A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":478
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2302
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SLC22A25. Does this perturbation cause a significant change in SLC22A25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXO4 and then measure expression of SLC22A25. Does this perturbation cause a significant change in SLC22A25 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1834
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and MARCKS expression is observed. Does this perturbation lead to a significant difference in MARCKS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and MARCKS expression is observed. Does this perturbation lead to a significant difference in MARCKS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4993
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of RP11-968A15.2. Does this perturbation cause a significant change in RP11-968A15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of RP11-968A15.2. Does this perturbation cause a significant change in RP11-968A15.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":834
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and IGDCC3 expression is observed. Does this perturbation lead to a significant difference in IGDCC3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2323
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of MACF1. Does perturbing ARID1A lead to a significant change in MACF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of MACF1. Does perturbing ARID1A lead to a significant change in MACF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4731
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in MYC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in MYC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3025
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SOCS2 expression is quantified. Does this perturbation result in a significant change in SOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SOCS2 expression is quantified. Does this perturbation result in a significant change in SOCS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":692
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3306
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of FAM49A. Does perturbing MEIS1 lead to a significant change in FAM49A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of FAM49A. Does perturbing MEIS1 lead to a significant change in FAM49A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":471
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and TCAF2 expression is measured. Determine whether TCAF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and TCAF2 expression is measured. Determine whether TCAF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2979
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and AC004540.4 expression is quantified. Does this perturbation result in a significant change in AC004540.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and AC004540.4 expression is quantified. Does this perturbation result in a significant change in AC004540.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4122
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor FEV expression. Decide whether this perturbation leads to a significant alteration in FEV expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1328
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-646I6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-646I6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and RP11-646I6.6 expression is observed. Does this perturbation lead to a significant difference in RP11-646I6.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1073
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MYOZ3 expression. Decide whether this perturbation leads to a significant alteration in MYOZ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor MYOZ3 expression. Decide whether this perturbation leads to a significant alteration in MYOZ3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3948
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1020
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and SAT2 expression is observed. Does this perturbation lead to a significant difference in SAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3073
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of NCKAP1L. Does perturbing CITED1 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of NCKAP1L. Does perturbing CITED1 lead to a significant change in NCKAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5921
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SPANXN5 expression. Decide whether this perturbation leads to a significant alteration in SPANXN5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL1A1 and monitor SPANXN5 expression. Decide whether this perturbation leads to a significant alteration in SPANXN5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3468
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor MMP19 expression. Decide whether this perturbation leads to a significant alteration in MMP19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor MMP19 expression. Decide whether this perturbation leads to a significant alteration in MMP19 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":948
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Does this perturbation cause a significant change in PLA2G16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Does this perturbation cause a significant change in PLA2G16 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6150
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TUBB2B expression is quantified. Does this perturbation result in a significant change in TUBB2B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1582
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Determine whether VMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of VMP1 is measured. Determine whether VMP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5866
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and GIPC2 expression is measured. Determine whether GIPC2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3159
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of FAM101B is measured. Does this perturbation cause a significant change in FAM101B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":300
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PAMR1 expression is quantified. Does this perturbation result in a significant change in PAMR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PAMR1 expression is quantified. Does this perturbation result in a significant change in PAMR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4792
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Determine whether CCRL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":346
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of CRYAB. Does this perturbation cause a significant change in CRYAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of CRYAB. Does this perturbation cause a significant change in CRYAB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1344
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of AC007193.6. Does perturbing PTPN12 lead to a significant change in AC007193.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of AC007193.6. Does perturbing PTPN12 lead to a significant change in AC007193.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2631
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SOCS3. Does perturbing COL1A1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of SOCS3. Does perturbing COL1A1 lead to a significant change in SOCS3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3451
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Determine whether BCL2L11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of BCL2L11 is measured. Determine whether BCL2L11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4926
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of RPS6KA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of RPS6KA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1607
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of CCR10 is measured. Does this perturbation cause a significant change in CCR10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1860
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of DLX4. Does this perturbation cause a significant change in DLX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of DLX4. Does this perturbation cause a significant change in DLX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6164
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRTG and monitor CISH expression. Decide whether this perturbation leads to a significant alteration in CISH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3608
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Determine whether LRRC36 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Determine whether LRRC36 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":336
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and AGXT expression is quantified. Does this perturbation result in a significant change in AGXT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC4A1 is perturbed and AGXT expression is quantified. Does this perturbation result in a significant change in AGXT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1052
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Determine whether GCM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Determine whether GCM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1356
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CCS expression is observed. Does this perturbation lead to a significant difference in CCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CCS expression is observed. Does this perturbation lead to a significant difference in CCS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":133
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ARL6IP1. Does this perturbation cause a significant change in ARL6IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ARL6IP1. Does this perturbation cause a significant change in ARL6IP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2934
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of NUDC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of NUDC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2157
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ANXA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP2K6, does the expression profile of ANXA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3967
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of NPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of NPW indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6047
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor ALAS2 expression. Decide whether this perturbation leads to a significant alteration in ALAS2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2308
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTSL. Does perturbing RREB1 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTSL. Does perturbing RREB1 lead to a significant change in CTSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1091
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Does this perturbation cause a significant change in MME expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1C is perturbed and the expression of MME is measured. Does this perturbation cause a significant change in MME expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6260
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and FAM101B expression is observed. Does this perturbation lead to a significant difference in FAM101B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1143
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of CST3 is measured. Does this perturbation cause a significant change in CST3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2740
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of AC020571.3. Does perturbing COL2A1 lead to a significant change in AC020571.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of AC020571.3. Does perturbing COL2A1 lead to a significant change in AC020571.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1211
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2064
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Determine whether FOXF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3496
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of RP4-565E6.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of RP4-565E6.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":297
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in SERPINF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in SERPINF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1085
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of ANXA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2837
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ANTXR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of ANTXR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5587
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of AC139099.6. Does perturbing COL1A1 lead to a significant change in AC139099.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of AC139099.6. Does perturbing COL1A1 lead to a significant change in AC139099.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3471
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ZIC4 expression is quantified. Does this perturbation result in a significant change in ZIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and ZIC4 expression is quantified. Does this perturbation result in a significant change in ZIC4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2612
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and CISH expression is measured. Determine whether CISH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3609
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and RGS16 expression is quantified. Does this perturbation result in a significant change in RGS16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":212
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of FOXF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3497
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of FZD6. Does perturbing IRF1 lead to a significant change in FZD6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of FZD6. Does perturbing IRF1 lead to a significant change in FZD6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2991
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4270
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of TXNIP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4697
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Determine whether CTD-3131K8.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of CTD-3131K8.3 is measured. Determine whether CTD-3131K8.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2756
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Does this perturbation cause a significant change in TAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Does this perturbation cause a significant change in TAC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3800
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4379
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and TRPM2 expression is quantified. Does this perturbation result in a significant change in TRPM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and TRPM2 expression is quantified. Does this perturbation result in a significant change in TRPM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1422
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of GRN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5887
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ZIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of ZIC4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2617
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ACP5 expression is observed. Does this perturbation lead to a significant difference in ACP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and ACP5 expression is observed. Does this perturbation lead to a significant difference in ACP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1203
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01358 expression is measured. Determine whether LINC01358 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01358 expression is measured. Determine whether LINC01358 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5619
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ICAM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in ICAM4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4745
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of PIM2. Does perturbing IRF1 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of PIM2. Does perturbing IRF1 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2951
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is quantified. Does this perturbation result in a significant change in RP11-442O1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is quantified. Does this perturbation result in a significant change in RP11-442O1.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4662
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in TRAPPC3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in TRAPPC3L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6255
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Determine whether AC144568.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of AC144568.2 is measured. Determine whether AC144568.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":596
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor RP4-565E6.1 expression. Decide whether this perturbation leads to a significant alteration in RP4-565E6.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor RP4-565E6.1 expression. Decide whether this perturbation leads to a significant alteration in RP4-565E6.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":298
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of KIAA2012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of KIAA2012 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":117
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PSMB9 expression. Decide whether this perturbation leads to a significant alteration in PSMB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor PSMB9 expression. Decide whether this perturbation leads to a significant alteration in PSMB9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5288
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and AGXT expression is observed. Does this perturbation lead to a significant difference in AGXT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and AGXT expression is observed. Does this perturbation lead to a significant difference in AGXT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1053
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in NUDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in NUDC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2155
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FADS1. Does perturbing FOXL2 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of FADS1. Does perturbing FOXL2 lead to a significant change in FADS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4101
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Determine whether PAMR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PAMR1 is measured. Determine whether PAMR1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4796
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in NCF4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":725
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and TNNI3 expression is measured. Determine whether TNNI3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1729
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RP4-550H1.4. Does perturbing PTPN9 lead to a significant change in RP4-550H1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RP4-550H1.4. Does perturbing PTPN9 lead to a significant change in RP4-550H1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5791
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Does this perturbation cause a significant change in ACTC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ACTC1 is measured. Does this perturbation cause a significant change in ACTC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5370
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4772
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and HIST1H4H expression is quantified. Does this perturbation result in a significant change in HIST1H4H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and HIST1H4H expression is quantified. Does this perturbation result in a significant change in HIST1H4H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4342
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and HEATR9 expression is observed. Does this perturbation lead to a significant difference in HEATR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and HEATR9 expression is observed. Does this perturbation lead to a significant difference in HEATR9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2383
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ACTC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ACTC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5375
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Does this perturbation cause a significant change in RP11-195B3.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of RP11-195B3.1 is measured. Does this perturbation cause a significant change in RP11-195B3.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2210
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in AGXT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in AGXT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1055
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor FBXL20 expression. Decide whether this perturbation leads to a significant alteration in FBXL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5768
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Does this perturbation cause a significant change in MYO1F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of MYO1F is measured. Does this perturbation cause a significant change in MYO1F expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1510
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RP11-308D13.3. Does perturbing CBL lead to a significant change in RP11-308D13.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RP11-308D13.3. Does perturbing CBL lead to a significant change in RP11-308D13.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":761
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Determine whether LINC01342 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of LINC01342 is measured. Determine whether LINC01342 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2206
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1869
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of RBM5-AS1. Does this perturbation cause a significant change in RBM5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of RBM5-AS1. Does this perturbation cause a significant change in RBM5-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":164
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Does this perturbation cause a significant change in RP11-259K5.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of RP11-259K5.1 is measured. Does this perturbation cause a significant change in RP11-259K5.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1240
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Does this perturbation cause a significant change in RP11-290L1.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Does this perturbation cause a significant change in RP11-290L1.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2030
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in HBD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5105
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RNF168. Does perturbing CBL lead to a significant change in RNF168 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of RNF168. Does perturbing CBL lead to a significant change in RNF168 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":771
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LINC01562 expression is measured. Determine whether LINC01562 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and LINC01562 expression is measured. Determine whether LINC01562 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1319
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is quantified. Does this perturbation result in a significant change in RP11-1017G21.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-1017G21.6 expression is quantified. Does this perturbation result in a significant change in RP11-1017G21.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3822
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3617
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PPFIA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of PPFIA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5307
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is measured. Determine whether CTD-3037G24.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTD-3037G24.4 expression is measured. Determine whether CTD-3037G24.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1439
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of HEMGN. Does perturbing DLX2 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of HEMGN. Does perturbing DLX2 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1561
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AP1S2 expression is measured. Determine whether AP1S2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4269
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01358 expression is quantified. Does this perturbation result in a significant change in LINC01358 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB10 is perturbed and LINC01358 expression is quantified. Does this perturbation result in a significant change in LINC01358 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5612
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of GCM2. Does this perturbation cause a significant change in GCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of GCM2. Does this perturbation cause a significant change in GCM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1354
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor GIPC2 expression. Decide whether this perturbation leads to a significant alteration in GIPC2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4488
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of ZNF431 is measured. Does this perturbation cause a significant change in ZNF431 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5830
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and NBR1 expression is measured. Determine whether NBR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4279
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2847
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CHP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CHP1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5465
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in LBH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CITED1 is associated with a significant change in LBH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5935
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1563
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":54
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3629
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Does this perturbation cause a significant change in SPARC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of SPARC is measured. Does this perturbation cause a significant change in SPARC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5520
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Determine whether HEATR9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1A is perturbed and the expression of HEATR9 is measured. Determine whether HEATR9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2386
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Determine whether SIGLEC15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Determine whether SIGLEC15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1966
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of FBXL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5767
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTB-161C1.1. Does perturbing UBASH3B lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of CTB-161C1.1. Does perturbing UBASH3B lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1411
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Determine whether TLCD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, JUN is perturbed and the expression of TLCD2 is measured. Determine whether TLCD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5556
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1562
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and KRTAP9-9 expression is observed. Does this perturbation lead to a significant difference in KRTAP9-9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and KRTAP9-9 expression is observed. Does this perturbation lead to a significant difference in KRTAP9-9 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5293
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of ESAM is measured. Does this perturbation cause a significant change in ESAM expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5270
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4964
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in LINC01342 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in LINC01342 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2205
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor KIAA2012 expression. Decide whether this perturbation leads to a significant alteration in KIAA2012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor KIAA2012 expression. Decide whether this perturbation leads to a significant alteration in KIAA2012 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":118
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Determine whether RBM5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Determine whether RBM5-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":166
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4813
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CRAT37 expression is observed. Does this perturbation lead to a significant difference in CRAT37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and CRAT37 expression is observed. Does this perturbation lead to a significant difference in CRAT37 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6193
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL1A1 is perturbed and the expression of C10orf11 is measured. Determine whether C10orf11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3436
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of MFGE8. Does this perturbation cause a significant change in MFGE8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5944
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5457
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CPXM1 expression is measured. Determine whether CPXM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and CPXM1 expression is measured. Determine whether CPXM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":389
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Does this perturbation cause a significant change in ACE expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3650
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of SLC31A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of SLC31A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5417
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in DCAF13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in DCAF13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3545
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Determine whether TNFAIP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of TNFAIP8 is measured. Determine whether TNFAIP8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2186
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor RPS6KA2 expression. Decide whether this perturbation leads to a significant alteration in RPS6KA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor RPS6KA2 expression. Decide whether this perturbation leads to a significant alteration in RPS6KA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1608
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and HMOX1 expression is quantified. Does this perturbation result in a significant change in HMOX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CITED1 is perturbed and HMOX1 expression is quantified. Does this perturbation result in a significant change in HMOX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5972
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLA2G16. Does perturbing KIF18B lead to a significant change in PLA2G16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of PLA2G16. Does perturbing KIF18B lead to a significant change in PLA2G16 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6151
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Does this perturbation cause a significant change in SOCS3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2840
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of SOCS3 is measured. Determine whether SOCS3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2846
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and CCNB2 expression is observed. Does this perturbation lead to a significant difference in CCNB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and CCNB2 expression is observed. Does this perturbation lead to a significant difference in CCNB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4333
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in CLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in CLU expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":15
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Does this perturbation cause a significant change in ARHGEF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of ARHGEF6 is measured. Does this perturbation cause a significant change in ARHGEF6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2110
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of RP11-290L1.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of RP11-290L1.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2037
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is quantified. Does this perturbation result in a significant change in PCDHGA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is quantified. Does this perturbation result in a significant change in PCDHGA6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1302
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5159
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ACTC1 expression. Decide whether this perturbation leads to a significant alteration in ACTC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor ACTC1 expression. Decide whether this perturbation leads to a significant alteration in ACTC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5378
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCDC148 expression is observed. Does this perturbation lead to a significant difference in CCDC148 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and CCDC148 expression is observed. Does this perturbation lead to a significant difference in CCDC148 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2133
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3555
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3913
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in STAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in STAC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":275
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and NCF4 expression is measured. Determine whether NCF4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":729
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CD37. Does this perturbation cause a significant change in CD37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of CD37. Does this perturbation cause a significant change in CD37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3244
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of CTB-161C1.1. Does this perturbation cause a significant change in CTB-161C1.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4234
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Determine whether SDSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SDSL is measured. Determine whether SDSL shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2426
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and STRA6 expression is measured. Determine whether STRA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and STRA6 expression is measured. Determine whether STRA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":659
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of RP11-195C7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HES7, does the expression profile of RP11-195C7.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1737
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of LINC01342 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of LINC01342 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2207
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and FOXL2 expression is observed. Does this perturbation lead to a significant difference in FOXL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3683
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and RGS16 expression is measured. Determine whether RGS16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":219
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and RP11-202A13.1 expression is observed. Does this perturbation lead to a significant difference in RP11-202A13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and RP11-202A13.1 expression is observed. Does this perturbation lead to a significant difference in RP11-202A13.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4783
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Does this perturbation cause a significant change in CEBPD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of CEBPD is measured. Does this perturbation cause a significant change in CEBPD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6060
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of CD52. Does this perturbation cause a significant change in CD52 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":804
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and PDE1B expression is measured. Determine whether PDE1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and PDE1B expression is measured. Determine whether PDE1B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":39
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and RLN3 expression is measured. Determine whether RLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and RLN3 expression is measured. Determine whether RLN3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5009
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of XX-FW83563B9.5. Does perturbing CLDN6 lead to a significant change in XX-FW83563B9.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of XX-FW83563B9.5. Does perturbing CLDN6 lead to a significant change in XX-FW83563B9.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3291
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5025
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTB-161C1.1 is measured. Does this perturbation cause a significant change in CTB-161C1.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1410
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":923
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM118A. Does perturbing TP73 lead to a significant change in FAM118A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of FAM118A. Does perturbing TP73 lead to a significant change in FAM118A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2661
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1649
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and AMPH expression is measured. Determine whether AMPH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRDM1 is perturbed and AMPH expression is measured. Determine whether AMPH exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6019
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CDK1 expression is measured. Determine whether CDK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and CDK1 expression is measured. Determine whether CDK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4409
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of ZNF467. Does this perturbation cause a significant change in ZNF467 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":874
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PSMB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ATL1 is associated with a significant change in PSMB9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5285
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Does this perturbation cause a significant change in ADGB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of ADGB is measured. Does this perturbation cause a significant change in ADGB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5540
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CST3. Does perturbing MAP7D1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CST3. Does perturbing MAP7D1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2741
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and PCK1 expression is quantified. Does this perturbation result in a significant change in PCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and PCK1 expression is quantified. Does this perturbation result in a significant change in PCK1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5732
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor SERPINF1 expression. Decide whether this perturbation leads to a significant alteration in SERPINF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor SERPINF1 expression. Decide whether this perturbation leads to a significant alteration in SERPINF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1088
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of SEMA3B. Does this perturbation cause a significant change in SEMA3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPA and then measure expression of SEMA3B. Does this perturbation cause a significant change in SEMA3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4244
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and MARCKS expression is quantified. Does this perturbation result in a significant change in MARCKS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZC3HAV1 is perturbed and MARCKS expression is quantified. Does this perturbation result in a significant change in MARCKS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ADGRF1 expression. Decide whether this perturbation leads to a significant alteration in ADGRF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor ADGRF1 expression. Decide whether this perturbation leads to a significant alteration in ADGRF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5728
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in PROX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in PROX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4055
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIST1H2AC expression is quantified. Does this perturbation result in a significant change in HIST1H2AC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3182
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and DRC1 expression is quantified. Does this perturbation result in a significant change in DRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and DRC1 expression is quantified. Does this perturbation result in a significant change in DRC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5662
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTC-492K19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTC-492K19.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1125
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":490
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and AC007556.3 expression is observed. Does this perturbation lead to a significant difference in AC007556.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and AC007556.3 expression is observed. Does this perturbation lead to a significant difference in AC007556.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":823
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and PIM2 expression is observed. Does this perturbation lead to a significant difference in PIM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":913
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Determine whether PPP4R4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Determine whether PPP4R4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4616
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of DNAJB1. Does this perturbation cause a significant change in DNAJB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of DNAJB1. Does this perturbation cause a significant change in DNAJB1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3864
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ATF6B. Does perturbing NIT1 lead to a significant change in ATF6B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ATF6B. Does perturbing NIT1 lead to a significant change in ATF6B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5321
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and AK8 expression is measured. Determine whether AK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and AK8 expression is measured. Determine whether AK8 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4399
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and TAS1R1 expression is quantified. Does this perturbation result in a significant change in TAS1R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and TAS1R1 expression is quantified. Does this perturbation result in a significant change in TAS1R1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":702
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of TCAF2. Does this perturbation cause a significant change in TCAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of TCAF2. Does this perturbation cause a significant change in TCAF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2974
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA1 is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":326
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5630
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Determine whether HBD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5106
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":807
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CTD-2527I21.14 is measured. Does this perturbation cause a significant change in CTD-2527I21.14 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4410
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CYP3A5. Does perturbing SET lead to a significant change in CYP3A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SET and examine the expression of CYP3A5. Does perturbing SET lead to a significant change in CYP3A5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":861
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Does this perturbation cause a significant change in FEV expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2460
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and GIPR expression is quantified. Does this perturbation result in a significant change in GIPR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and GIPR expression is quantified. Does this perturbation result in a significant change in GIPR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5352
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of AC006262.5. Does perturbing SAMD1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of AC006262.5. Does perturbing SAMD1 lead to a significant change in AC006262.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3371
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3796
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of DST is measured. Does this perturbation cause a significant change in DST expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2340
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and C1orf228 expression is observed. Does this perturbation lead to a significant difference in C1orf228 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and C1orf228 expression is observed. Does this perturbation lead to a significant difference in C1orf228 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1113
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Does this perturbation cause a significant change in TRPM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Does this perturbation cause a significant change in TRPM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1420
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Does this perturbation cause a significant change in IGFL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Does this perturbation cause a significant change in IGFL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5490
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Determine whether TFRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of TFRC is measured. Determine whether TFRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1226
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3733
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLEKHO1 expression. Decide whether this perturbation leads to a significant alteration in PLEKHO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor PLEKHO1 expression. Decide whether this perturbation leads to a significant alteration in PLEKHO1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6128
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of SKAP2. Does perturbing LHX1 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of SKAP2. Does perturbing LHX1 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":961
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SLC20A1. Does perturbing PTPN1 lead to a significant change in SLC20A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SLC20A1. Does perturbing PTPN1 lead to a significant change in SLC20A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2401
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4622
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Determine whether RP5-1142A6.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Determine whether RP5-1142A6.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4716
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Determine whether RP11-445O3.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP11-445O3.3 is measured. Determine whether RP11-445O3.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":46
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and PROX1 expression is observed. Does this perturbation lead to a significant difference in PROX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SGK1 is perturbed and PROX1 expression is observed. Does this perturbation lead to a significant difference in PROX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4053
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":0
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in AC020571.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL2A1 is associated with a significant change in AC020571.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1215
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of BMP2K indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of BMP2K indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1507
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TUBA1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TUBA1A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2717
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor NUDC expression. Decide whether this perturbation leads to a significant alteration in NUDC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor NUDC expression. Decide whether this perturbation leads to a significant alteration in NUDC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2158
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ADGB expression is quantified. Does this perturbation result in a significant change in ADGB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and ADGB expression is quantified. Does this perturbation result in a significant change in ADGB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5542
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5948
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of FABP5. Does this perturbation cause a significant change in FABP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3064
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3A and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4824
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and UBE2H expression is observed. Does this perturbation lead to a significant difference in UBE2H expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2363
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor CSRNP1 expression. Decide whether this perturbation leads to a significant alteration in CSRNP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CSRNP1 and monitor CSRNP1 expression. Decide whether this perturbation leads to a significant alteration in CSRNP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4648
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of DRC1. Does this perturbation cause a significant change in DRC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of DRC1. Does this perturbation cause a significant change in DRC1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5664
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ATP8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ATP8A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3525
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and AMHR2 expression is quantified. Does this perturbation result in a significant change in AMHR2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6102
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3017
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of FMNL1. Does perturbing HES7 lead to a significant change in FMNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of FMNL1. Does perturbing HES7 lead to a significant change in FMNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1691
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Does this perturbation cause a significant change in RP11-38J22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HK2 is perturbed and the expression of RP11-38J22.3 is measured. Does this perturbation cause a significant change in RP11-38J22.3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6070
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of LST1. Does this perturbation cause a significant change in LST1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1264
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and LGALS12 expression is quantified. Does this perturbation result in a significant change in LGALS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DUSP9 is perturbed and LGALS12 expression is quantified. Does this perturbation result in a significant change in LGALS12 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":182
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2582
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RP4-550H1.4 expression. Decide whether this perturbation leads to a significant alteration in RP4-550H1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor RP4-550H1.4 expression. Decide whether this perturbation leads to a significant alteration in RP4-550H1.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5798
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ABCA6 expression is observed. Does this perturbation lead to a significant difference in ABCA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ABCA6 expression is observed. Does this perturbation lead to a significant difference in ABCA6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4173
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in FAM225B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in FAM225B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5235
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is quantified. Does this perturbation result in a significant change in HIPK1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and HIPK1-AS1 expression is quantified. Does this perturbation result in a significant change in HIPK1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3222
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Determine whether PCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of PCK1 is measured. Determine whether PCK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5736
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP6-159A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP6-159A1.4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2825
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1568
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Determine whether PPFIA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of PPFIA4 is measured. Determine whether PPFIA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5306
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and XK expression is measured. Determine whether XK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and XK expression is measured. Determine whether XK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2629
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in HBE1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in HBE1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":445
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Does this perturbation cause a significant change in CITED2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of CITED2 is measured. Does this perturbation cause a significant change in CITED2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4280
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of CFH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5447
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4239
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of IGFL2. Does perturbing TGFBR2 lead to a significant change in IGFL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of IGFL2. Does perturbing TGFBR2 lead to a significant change in IGFL2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5491
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of AMHR2 is measured. Determine whether AMHR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6106
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SDSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in SDSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2425
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTD-3037G24.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3037G24.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTD-3037G24.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3037G24.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1433
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of MARCKS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of MARCKS indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4997
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ZMYND15. Does this perturbation cause a significant change in ZMYND15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of ZMYND15. Does this perturbation cause a significant change in ZMYND15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2734
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor WDR88 expression. Decide whether this perturbation leads to a significant alteration in WDR88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor WDR88 expression. Decide whether this perturbation leads to a significant alteration in WDR88 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4728
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and MOGAT2 expression is observed. Does this perturbation lead to a significant difference in MOGAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and MOGAT2 expression is observed. Does this perturbation lead to a significant difference in MOGAT2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5533
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of LHX1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":617
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CD37 expression. Decide whether this perturbation leads to a significant alteration in CD37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor CD37 expression. Decide whether this perturbation leads to a significant alteration in CD37 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3248
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor C1orf228 expression. Decide whether this perturbation leads to a significant alteration in C1orf228 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor C1orf228 expression. Decide whether this perturbation leads to a significant alteration in C1orf228 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1118
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Does this perturbation cause a significant change in STRA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Does this perturbation cause a significant change in STRA6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":650
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and YPEL3 expression is quantified. Does this perturbation result in a significant change in YPEL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and YPEL3 expression is quantified. Does this perturbation result in a significant change in YPEL3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5752
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4528
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in YPEL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in YPEL3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5755
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TMEM55A. Does this perturbation cause a significant change in TMEM55A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TMEM55A. Does this perturbation cause a significant change in TMEM55A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4604
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and SPTAN1 expression is measured. Determine whether SPTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and SPTAN1 expression is measured. Determine whether SPTAN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2169
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Does this perturbation cause a significant change in LINC01003 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of LINC01003 is measured. Does this perturbation cause a significant change in LINC01003 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":450
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HHEX expression. Decide whether this perturbation leads to a significant alteration in HHEX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor HHEX expression. Decide whether this perturbation leads to a significant alteration in HHEX expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3388
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CENPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CENPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6227
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and CTSS expression is observed. Does this perturbation lead to a significant difference in CTSS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and CTSS expression is observed. Does this perturbation lead to a significant difference in CTSS expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2023
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01395 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in LINC01395 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5595
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and TMEM35 expression is observed. Does this perturbation lead to a significant difference in TMEM35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZC3HAV1 is perturbed and TMEM35 expression is observed. Does this perturbation lead to a significant difference in TMEM35 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5013
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and DNAJB1 expression is quantified. Does this perturbation result in a significant change in DNAJB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3862
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and PAQR7 expression is measured. Determine whether PAQR7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":999
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Does this perturbation cause a significant change in SOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX2 is perturbed and the expression of SOX5 is measured. Does this perturbation cause a significant change in SOX5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2470
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3786
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of COLGALT2. Does this perturbation cause a significant change in COLGALT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4094
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of TAPBP. Does perturbing MAP2K3 lead to a significant change in TAPBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of TAPBP. Does perturbing MAP2K3 lead to a significant change in TAPBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2231
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTSL expression is measured. Determine whether CTSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1099
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor CCRL2 expression. Decide whether this perturbation leads to a significant alteration in CCRL2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":348
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Does this perturbation cause a significant change in FAM49A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Does this perturbation cause a significant change in FAM49A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":470
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-109E24.2. Does this perturbation cause a significant change in RP11-109E24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of RP11-109E24.2. Does this perturbation cause a significant change in RP11-109E24.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6214
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4158
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is quantified. Does this perturbation result in a significant change in RP1-102K2.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2982
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Determine whether TPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Determine whether TPP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1576
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and CBL expression is quantified. Does this perturbation result in a significant change in CBL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and CBL expression is quantified. Does this perturbation result in a significant change in CBL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3142
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PCDHGA6 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PCDHGA6 expression. Decide whether this perturbation leads to a significant alteration in PCDHGA6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1308
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Determine whether APOBR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Determine whether APOBR shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5176
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of SAT2. Does perturbing C19orf26 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of SAT2. Does perturbing C19orf26 lead to a significant change in SAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2881
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RUNX1T1 is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1952
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ZNF677 expression is observed. Does this perturbation lead to a significant difference in ZNF677 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and ZNF677 expression is observed. Does this perturbation lead to a significant difference in ZNF677 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3093
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of VASH1. Does this perturbation cause a significant change in VASH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of VASH1. Does this perturbation cause a significant change in VASH1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3354
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor CTSL expression. Decide whether this perturbation leads to a significant alteration in CTSL expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1098
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of TNFAIP2. Does perturbing CEBPB lead to a significant change in TNFAIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of TNFAIP2. Does perturbing CEBPB lead to a significant change in TNFAIP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5201
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in TRGVA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in TRGVA expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":955
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TFAP2A-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in TFAP2A-AS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4365
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ID1. Does perturbing CBL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CBL and examine the expression of ID1. Does perturbing CBL lead to a significant change in ID1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":741
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HCN1. Does this perturbation cause a significant change in HCN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of HCN1. Does this perturbation cause a significant change in HCN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3044
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Determine whether MAOB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of MAOB is measured. Determine whether MAOB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1496
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNDC3B. Does this perturbation cause a significant change in RUNDC3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of RUNDC3B. Does this perturbation cause a significant change in RUNDC3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2804
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and RBM5-AS1 expression is quantified. Does this perturbation result in a significant change in RBM5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and RBM5-AS1 expression is quantified. Does this perturbation result in a significant change in RBM5-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":162
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM83F expression. Decide whether this perturbation leads to a significant alteration in FAM83F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM83F expression. Decide whether this perturbation leads to a significant alteration in FAM83F expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2688
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-510J16.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in RP11-510J16.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1065
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of CISH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3607
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of KRT7. Does this perturbation cause a significant change in KRT7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2794
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and SERPINF1 expression is quantified. Does this perturbation result in a significant change in SERPINF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and SERPINF1 expression is quantified. Does this perturbation result in a significant change in SERPINF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1082
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PHLDA2. Does perturbing ZBTB25 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of PHLDA2. Does perturbing ZBTB25 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1271
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ST3GAL5. Does perturbing AHR lead to a significant change in ST3GAL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of ST3GAL5. Does perturbing AHR lead to a significant change in ST3GAL5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1761
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CTD-2527I21.14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IGDCC3, does the expression profile of CTD-2527I21.14 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4417
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SAT1. Does perturbing FOXO4 lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of SAT1. Does perturbing FOXO4 lead to a significant change in SAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1801
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CYP2C18 expression is quantified. Does this perturbation result in a significant change in CYP2C18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and CYP2C18 expression is quantified. Does this perturbation result in a significant change in CYP2C18 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":932
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Does this perturbation cause a significant change in ZNF610 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of ZNF610 is measured. Does this perturbation cause a significant change in ZNF610 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2430
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of RHOXF2BB. Does perturbing SLC38A2 lead to a significant change in RHOXF2BB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of RHOXF2BB. Does perturbing SLC38A2 lead to a significant change in RHOXF2BB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5711
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is measured. Determine whether COL18A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is measured. Determine whether COL18A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":639
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of CDC20 is measured. Does this perturbation cause a significant change in CDC20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1810
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1928
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX2 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2464
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of FAM178B. Does perturbing AHR lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb AHR and examine the expression of FAM178B. Does perturbing AHR lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1741
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and TLCD2 expression is quantified. Does this perturbation result in a significant change in TLCD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and TLCD2 expression is quantified. Does this perturbation result in a significant change in TLCD2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5552
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of CCR10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1487
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of KIF2C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4567
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of CSRNP1. Does this perturbation cause a significant change in CSRNP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of CSRNP1. Does this perturbation cause a significant change in CSRNP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4644
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of SKAP2. Does perturbing OSR2 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of SKAP2. Does perturbing OSR2 lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5041
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IKZF3 is perturbed and AVP expression is quantified. Does this perturbation result in a significant change in AVP expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3002
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TFAP2A-AS1 expression is observed. Does this perturbation lead to a significant difference in TFAP2A-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TFAP2A-AS1 expression is observed. Does this perturbation lead to a significant difference in TFAP2A-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4363
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of FABP5 is measured. Determine whether FABP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4326
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CKS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of CKS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2077
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of ID1. Does this perturbation cause a significant change in ID1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":744
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ARMCX3. Does this perturbation cause a significant change in ARMCX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of ARMCX3. Does this perturbation cause a significant change in ARMCX3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3974
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-514P8.2. Does this perturbation cause a significant change in RP11-514P8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of RP11-514P8.2. Does this perturbation cause a significant change in RP11-514P8.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3694
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and SAT1 expression is observed. Does this perturbation lead to a significant difference in SAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1803
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and CST9L expression is quantified. Does this perturbation result in a significant change in CST9L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and CST9L expression is quantified. Does this perturbation result in a significant change in CST9L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3332
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SAMD1 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3373
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Does this perturbation cause a significant change in ANXA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA2 is measured. Does this perturbation cause a significant change in ANXA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2830
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Determine whether PDE1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of PDE1B is measured. Determine whether PDE1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":36
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in SKAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2545
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of GIPR. Does perturbing NIT1 lead to a significant change in GIPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of GIPR. Does perturbing NIT1 lead to a significant change in GIPR expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5351
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of MACF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of MACF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4737
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Does this perturbation cause a significant change in RAB5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Does this perturbation cause a significant change in RAB5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":680
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and TMEM154 expression is measured. Determine whether TMEM154 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and TMEM154 expression is measured. Determine whether TMEM154 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4149
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of FAM225B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of FAM225B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5237
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in RP11-537H15.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in RP11-537H15.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2275
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Determine whether ATP9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ATP9A is measured. Determine whether ATP9A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":536
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MS4A2 expression is observed. Does this perturbation lead to a significant difference in MS4A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and MS4A2 expression is observed. Does this perturbation lead to a significant difference in MS4A2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3933
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CENPE. Does perturbing CDKN1C lead to a significant change in CENPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CENPE. Does perturbing CDKN1C lead to a significant change in CENPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6221
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K3, does the expression profile of AIF1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2287
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and DCAF13 expression is measured. Determine whether DCAF13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and DCAF13 expression is measured. Determine whether DCAF13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3549
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of TM4SF1-AS1. Does perturbing BPGM lead to a significant change in TM4SF1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of TM4SF1-AS1. Does perturbing BPGM lead to a significant change in TM4SF1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3751
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ABCB11 expression. Decide whether this perturbation leads to a significant alteration in ABCB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor ABCB11 expression. Decide whether this perturbation leads to a significant alteration in ABCB11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1668
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Does this perturbation cause a significant change in PSMB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of PSMB9 is measured. Does this perturbation cause a significant change in PSMB9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5280
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4464
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SNCG expression is quantified. Does this perturbation result in a significant change in SNCG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SNCG expression is quantified. Does this perturbation result in a significant change in SNCG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1982
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of LTC4S indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRTG, does the expression profile of LTC4S indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3647
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-563J2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of RP11-563J2.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3817
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":73
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA1, does the expression profile of AC016629.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":327
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Does this perturbation cause a significant change in ANTXR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Does this perturbation cause a significant change in ANTXR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5580
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ID3 expression is observed. Does this perturbation lead to a significant difference in ID3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3483
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2983
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and PRKAG2-AS1 expression is observed. Does this perturbation lead to a significant difference in PRKAG2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and PRKAG2-AS1 expression is observed. Does this perturbation lead to a significant difference in PRKAG2-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3163
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor DST expression. Decide whether this perturbation leads to a significant alteration in DST expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2348
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of MSRB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of MSRB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2657
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ACTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of POU3F2, does the expression profile of ACTB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2087
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXC13 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3155
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor AC007556.3 expression. Decide whether this perturbation leads to a significant alteration in AC007556.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ETS2 and monitor AC007556.3 expression. Decide whether this perturbation leads to a significant alteration in AC007556.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":828
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CCDC159 expression is measured. Determine whether CCDC159 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPA is perturbed and CCDC159 expression is measured. Determine whether CCDC159 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4259
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and RP11-244F12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-244F12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and RP11-244F12.2 expression is observed. Does this perturbation lead to a significant difference in RP11-244F12.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4533
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor ZMAT3 expression. Decide whether this perturbation leads to a significant alteration in ZMAT3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5138
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of AP1S2. Does this perturbation cause a significant change in AP1S2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4264
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Does this perturbation cause a significant change in CTD-3037G24.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1430
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5403
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of AC064834.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of AC064834.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2447
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and CCR10 expression is quantified. Does this perturbation result in a significant change in CCR10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1482
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and CEBPA expression is measured. Determine whether CEBPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and CEBPA expression is measured. Determine whether CEBPA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1639
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CTD-2031P19.5 expression is quantified. Does this perturbation result in a significant change in CTD-2031P19.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and CTD-2031P19.5 expression is quantified. Does this perturbation result in a significant change in CTD-2031P19.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":882
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of FZD6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IRF1, does the expression profile of FZD6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2997
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Does this perturbation cause a significant change in TOR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Does this perturbation cause a significant change in TOR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5340
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor COTL1 expression. Decide whether this perturbation leads to a significant alteration in COTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor COTL1 expression. Decide whether this perturbation leads to a significant alteration in COTL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1288
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is quantified. Does this perturbation result in a significant change in CTB-49A3.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is quantified. Does this perturbation result in a significant change in CTB-49A3.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3392
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PAMR1 expression is observed. Does this perturbation lead to a significant difference in PAMR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNNM4 is perturbed and PAMR1 expression is observed. Does this perturbation lead to a significant difference in PAMR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4793
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of PIM2. Does perturbing TBX3 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of PIM2. Does perturbing TBX3 lead to a significant change in PIM2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":911
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of CCS. Does this perturbation cause a significant change in CCS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":134
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Does this perturbation cause a significant change in TMEM35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of TMEM35 is measured. Does this perturbation cause a significant change in TMEM35 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5010
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Determine whether TAPBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Determine whether TAPBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2236
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CPXM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCORL1, does the expression profile of CPXM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":387
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and KRT7 expression is quantified. Does this perturbation result in a significant change in KRT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and KRT7 expression is quantified. Does this perturbation result in a significant change in KRT7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2792
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Does this perturbation cause a significant change in TRIM31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MEIS1 is perturbed and the expression of TRIM31 is measured. Does this perturbation cause a significant change in TRIM31 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":460
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNDC3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNDC3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2805
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5687
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CRAT37. Does perturbing EGR1 lead to a significant change in CRAT37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of CRAT37. Does perturbing EGR1 lead to a significant change in CRAT37 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6191
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in S100A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in S100A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1755
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in MSX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in MSX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4035
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP3-510H16.3 expression is observed. Does this perturbation lead to a significant difference in RP3-510H16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARRDC3 is perturbed and RP3-510H16.3 expression is observed. Does this perturbation lead to a significant difference in RP3-510H16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3833
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CTD-3126B10.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1A, does the expression profile of CTD-3126B10.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2397
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is quantified. Does this perturbation result in a significant change in PRKAG2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and PRKAG2-AS1 expression is quantified. Does this perturbation result in a significant change in PRKAG2-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3162
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of CCDC136 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of CCDC136 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5037
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Does this perturbation cause a significant change in SPTAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Does this perturbation cause a significant change in SPTAN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2160
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP6-159A1.4. Does this perturbation cause a significant change in RP6-159A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP6-159A1.4. Does this perturbation cause a significant change in RP6-159A1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2824
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6247
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of SERPINF1. Does this perturbation cause a significant change in SERPINF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RREB1 and then measure expression of SERPINF1. Does this perturbation cause a significant change in SERPINF1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1084
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of RAB5B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":687
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Determine whether CREB3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of CREB3L2 is measured. Determine whether CREB3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5996
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CRAT37 expression is quantified. Does this perturbation result in a significant change in CRAT37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CRAT37 expression is quantified. Does this perturbation result in a significant change in CRAT37 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6192
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ACP5 expression is measured. Determine whether ACP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and ACP5 expression is measured. Determine whether ACP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1209
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TNNI3 expression. Decide whether this perturbation leads to a significant alteration in TNNI3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2708
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is quantified. Does this perturbation result in a significant change in RP11-52L5.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and RP11-52L5.6 expression is quantified. Does this perturbation result in a significant change in RP11-52L5.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6202
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TFAP2A-AS1. Does perturbing KMT2A lead to a significant change in TFAP2A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TFAP2A-AS1. Does perturbing KMT2A lead to a significant change in TFAP2A-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4361
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Determine whether TAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of TAC3 is measured. Determine whether TAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3806
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM118A. Does this perturbation cause a significant change in FAM118A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of FAM118A. Does this perturbation cause a significant change in FAM118A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2664
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CYP3A5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of CYP3A5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":867
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Determine whether CTC-492K19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of CTC-492K19.4 is measured. Determine whether CTC-492K19.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1126
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AC007246.3. Does this perturbation cause a significant change in AC007246.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of AC007246.3. Does this perturbation cause a significant change in AC007246.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2294
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor EWSAT1 expression. Decide whether this perturbation leads to a significant alteration in EWSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor EWSAT1 expression. Decide whether this perturbation leads to a significant alteration in EWSAT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5318
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SET and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":858
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1014
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of AC020571.3. Does this perturbation cause a significant change in AC020571.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of AC020571.3. Does this perturbation cause a significant change in AC020571.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1214
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of ZNF431 is measured. Determine whether ZNF431 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4676
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of COL21A1. Does this perturbation cause a significant change in COL21A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IGDCC3 and then measure expression of COL21A1. Does this perturbation cause a significant change in COL21A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4424
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor TAC3 expression. Decide whether this perturbation leads to a significant alteration in TAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor TAC3 expression. Decide whether this perturbation leads to a significant alteration in TAC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3808
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MBP expression is observed. Does this perturbation lead to a significant difference in MBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and MBP expression is observed. Does this perturbation lead to a significant difference in MBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1003
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and KRT79 expression is quantified. Does this perturbation result in a significant change in KRT79 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and KRT79 expression is quantified. Does this perturbation result in a significant change in KRT79 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3882
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2943
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5686
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CRAT37. Does this perturbation cause a significant change in CRAT37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to EGR1 and then measure expression of CRAT37. Does this perturbation cause a significant change in CRAT37 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6194
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RP11-285F7.2 expression is observed. Does this perturbation lead to a significant difference in RP11-285F7.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and RP11-285F7.2 expression is observed. Does this perturbation lead to a significant difference in RP11-285F7.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4903
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DLX2 is associated with a significant change in AC074289.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1615
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ST3GAL5 expression is quantified. Does this perturbation result in a significant change in ST3GAL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and ST3GAL5 expression is quantified. Does this perturbation result in a significant change in ST3GAL5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1762
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and FEZ1 expression is observed. Does this perturbation lead to a significant difference in FEZ1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3563
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Determine whether S100A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of S100A4 is measured. Determine whether S100A4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1046
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Does this perturbation cause a significant change in NUCB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of NUCB2 is measured. Does this perturbation cause a significant change in NUCB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3130
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in CTNNB1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":505
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of RP11-244F12.2. Does this perturbation cause a significant change in RP11-244F12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of RP11-244F12.2. Does this perturbation cause a significant change in RP11-244F12.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4534
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of RP11-714G18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of RP11-714G18.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1857
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and S100A4 expression is observed. Does this perturbation lead to a significant difference in S100A4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC4A1 is perturbed and S100A4 expression is observed. Does this perturbation lead to a significant difference in S100A4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1043
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of WDR88. Does this perturbation cause a significant change in WDR88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of WDR88. Does this perturbation cause a significant change in WDR88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4724
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and AC016629.3 expression is quantified. Does this perturbation result in a significant change in AC016629.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3612
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and PYROXD2 expression is measured. Determine whether PYROXD2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2229
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor TRIM22 expression. Decide whether this perturbation leads to a significant alteration in TRIM22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4598
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor RP11-362K14.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-362K14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor RP11-362K14.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-362K14.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4188
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in UBE2H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2365
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-514P8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in RP11-514P8.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3695
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of HERPUD1 is measured. Does this perturbation cause a significant change in HERPUD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5820
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM118A expression. Decide whether this perturbation leads to a significant alteration in FAM118A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor FAM118A expression. Decide whether this perturbation leads to a significant alteration in FAM118A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2668
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of RP11-445F12.1. Does this perturbation cause a significant change in RP11-445F12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of RP11-445F12.1. Does this perturbation cause a significant change in RP11-445F12.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":604
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PSMB9. Does this perturbation cause a significant change in PSMB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PSMB9. Does this perturbation cause a significant change in PSMB9 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5284
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Determine whether ABCB11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBFA2T3 is perturbed and the expression of ABCB11 is measured. Determine whether ABCB11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1666
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of HEMGN. Does this perturbation cause a significant change in HEMGN expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":254
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4260
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is measured. Determine whether RP11-452C8.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and RP11-452C8.1 expression is measured. Determine whether RP11-452C8.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4079
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RUNX3 expression is measured. Determine whether RUNX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RUNX3 expression is measured. Determine whether RUNX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5959
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SLC2A3. Does perturbing IER5L lead to a significant change in SLC2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SLC2A3. Does perturbing IER5L lead to a significant change in SLC2A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2531
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1469
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of RLN3. Does perturbing ZC3HAV1 lead to a significant change in RLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of RLN3. Does perturbing ZC3HAV1 lead to a significant change in RLN3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5001
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of TM4SF1-AS1. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of TM4SF1-AS1. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3754
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-510J16.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-510J16.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor RP11-510J16.5 expression. Decide whether this perturbation leads to a significant alteration in RP11-510J16.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1068
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of TUBB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of TUBB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2647
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of NCALD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of NCALD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4837
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Determine whether MYL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of MYL4 is measured. Determine whether MYL4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5566
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of NCKAP1L is measured. Does this perturbation cause a significant change in NCKAP1L expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5920
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":425
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ATF6B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in ATF6B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5325
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of STIL is associated with a significant change in WBP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5165
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and FEZ1 expression is quantified. Does this perturbation result in a significant change in FEZ1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3562
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of IGDCC3 is measured. Does this perturbation cause a significant change in IGDCC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2320
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CCNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of CCNL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6147
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and PRKCB expression is quantified. Does this perturbation result in a significant change in PRKCB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3792
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in FADS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1455
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of RIT1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4917
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor CTNNB1 expression. Decide whether this perturbation leads to a significant alteration in CTNNB1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":508
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5509
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC38A2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5683
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of TPM4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4517
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RHOH. Does perturbing ISL2 lead to a significant change in RHOH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of RHOH. Does perturbing ISL2 lead to a significant change in RHOH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4451
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6235
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor SOX5 expression. Decide whether this perturbation leads to a significant alteration in SOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor SOX5 expression. Decide whether this perturbation leads to a significant alteration in SOX5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2478
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TRIM31 expression. Decide whether this perturbation leads to a significant alteration in TRIM31 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TRIM31 expression. Decide whether this perturbation leads to a significant alteration in TRIM31 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":468
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and MTURN expression is measured. Determine whether MTURN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and MTURN expression is measured. Determine whether MTURN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1889
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AC007246.3 expression is measured. Determine whether AC007246.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AC007246.3 expression is measured. Determine whether AC007246.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2299
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4685
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2745
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of PAQR7. Does perturbing LHX1 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of PAQR7. Does perturbing LHX1 lead to a significant change in PAQR7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":991
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Determine whether RHOXF2BB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC38A2 is perturbed and the expression of RHOXF2BB is measured. Determine whether RHOXF2BB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5716
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in MACF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in MACF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4735
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AMHR2. Does perturbing SLC38A2 lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of AMHR2. Does perturbing SLC38A2 lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5701
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of TOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of TOX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1367
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Determine whether TNFRSF12A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of TNFRSF12A is measured. Determine whether TNFRSF12A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3906
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is measured. Determine whether SLC2A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is measured. Determine whether SLC2A1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1999
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2960
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CCDC159 expression. Decide whether this perturbation leads to a significant alteration in CCDC159 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPA and monitor CCDC159 expression. Decide whether this perturbation leads to a significant alteration in CCDC159 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4258
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of NPW. Does perturbing HK2 lead to a significant change in NPW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of NPW. Does perturbing HK2 lead to a significant change in NPW expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6041
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RNF213 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":25
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3782
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and RELB expression is quantified. Does this perturbation result in a significant change in RELB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and RELB expression is quantified. Does this perturbation result in a significant change in RELB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5652
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in EGOT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in EGOT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5675
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ANXA2R expression is observed. Does this perturbation lead to a significant difference in ANXA2R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and ANXA2R expression is observed. Does this perturbation lead to a significant difference in ANXA2R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5873
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and TM4SF1-AS1 expression is observed. Does this perturbation lead to a significant difference in TM4SF1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BPGM is perturbed and TM4SF1-AS1 expression is observed. Does this perturbation lead to a significant difference in TM4SF1-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3753
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Does this perturbation cause a significant change in CCNJL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of CCNJL is measured. Does this perturbation cause a significant change in CCNJL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5120
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is measured. Determine whether CTD-2378E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CTD-2378E12.1 expression is measured. Determine whether CTD-2378E12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6279
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of APOBR. Does this perturbation cause a significant change in APOBR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of APOBR. Does this perturbation cause a significant change in APOBR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5174
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in TCAF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in TCAF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2975
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2128
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SDSL. Does perturbing PTPN1 lead to a significant change in SDSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of SDSL. Does perturbing PTPN1 lead to a significant change in SDSL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2421
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ATG2A expression is observed. Does this perturbation lead to a significant difference in ATG2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and ATG2A expression is observed. Does this perturbation lead to a significant difference in ATG2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3633
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of DCAF13. Does this perturbation cause a significant change in DCAF13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB1 and then measure expression of DCAF13. Does this perturbation cause a significant change in DCAF13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3544
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor RSPO4 expression. Decide whether this perturbation leads to a significant alteration in RSPO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor RSPO4 expression. Decide whether this perturbation leads to a significant alteration in RSPO4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4118
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-109E24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-109E24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor RP11-109E24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-109E24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6218
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4233
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN9 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5742
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in CTA-384D8.34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BAK1 is associated with a significant change in CTA-384D8.34 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":645
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and WDR88 expression is measured. Determine whether WDR88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and WDR88 expression is measured. Determine whether WDR88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4729
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1278
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CRYM expression is quantified. Does this perturbation result in a significant change in CRYM expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3842
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of SOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of SOX5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2477
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD52. Does perturbing ETS2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of CD52. Does perturbing ETS2 lead to a significant change in CD52 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":801
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and TRIM22 expression is measured. Determine whether TRIM22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4599
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4574
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is quantified. Does this perturbation result in a significant change in RP11-76E17.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is quantified. Does this perturbation result in a significant change in RP11-76E17.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3342
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and HBG1 expression is observed. Does this perturbation lead to a significant difference in HBG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1B is perturbed and HBG1 expression is observed. Does this perturbation lead to a significant difference in HBG1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5383
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of RP11-38J22.3. Does this perturbation cause a significant change in RP11-38J22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of RP11-38J22.3. Does this perturbation cause a significant change in RP11-38J22.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6074
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KMT2A is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4373
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RNF213. Does perturbing OSR2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of RNF213. Does perturbing OSR2 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5021
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in KCNH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in KCNH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3445
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and FAM101B expression is measured. Determine whether FAM101B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":309
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Determine whether AGXT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Determine whether AGXT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1056
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4040
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of S100A13 is measured. Does this perturbation cause a significant change in S100A13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1820
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of PKIG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of PKIG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":207
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and HMGA2 expression is quantified. Does this perturbation result in a significant change in HMGA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and HMGA2 expression is quantified. Does this perturbation result in a significant change in HMGA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3892
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of MFGE8 is measured. Determine whether MFGE8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5946
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CACNA1C-AS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in CACNA1C-AS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":355
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and MYC expression is measured. Determine whether MYC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and MYC expression is measured. Determine whether MYC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3029
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in ARHGDIB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1335
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SDSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of SDSL indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2427
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of APOBR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of APOBR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5177
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and SKAP2 expression is measured. Determine whether SKAP2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5049
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of LMNA. Does perturbing HES7 lead to a significant change in LMNA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of LMNA. Does perturbing HES7 lead to a significant change in LMNA expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1681
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of COL1A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of COL1A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5057
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in DPYSL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SNAI1 is associated with a significant change in DPYSL2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5805
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MS4A2 expression is measured. Determine whether MS4A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LYL1 is perturbed and MS4A2 expression is measured. Determine whether MS4A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3939
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Determine whether RABAC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Determine whether RABAC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5146
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of CNN2. Does perturbing ARID1A lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of CNN2. Does perturbing ARID1A lead to a significant change in CNN2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4701
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Determine whether UCKL1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Determine whether UCKL1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5256
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor TMEM154 expression. Decide whether this perturbation leads to a significant alteration in TMEM154 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIAA1804 and monitor TMEM154 expression. Decide whether this perturbation leads to a significant alteration in TMEM154 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4148
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of PERM1. Does perturbing TGFBR2 lead to a significant change in PERM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of PERM1. Does perturbing TGFBR2 lead to a significant change in PERM1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5481
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in TYROBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":795
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of FEV. Does perturbing TBX3 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of FEV. Does perturbing TBX3 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":921
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and S100A3 expression is observed. Does this perturbation lead to a significant difference in S100A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and S100A3 expression is observed. Does this perturbation lead to a significant difference in S100A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1913
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of RSPO4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of RSPO4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4117
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LHX1 is perturbed and SKAP2 expression is quantified. Does this perturbation result in a significant change in SKAP2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":962
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ZNF610. Does this perturbation cause a significant change in ZNF610 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of ZNF610. Does this perturbation cause a significant change in ZNF610 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2434
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of HOXB6. Does perturbing ETS2 lead to a significant change in HOXB6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ETS2 and examine the expression of HOXB6. Does perturbing ETS2 lead to a significant change in HOXB6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":811
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of TACC1. Does perturbing PRDM1 lead to a significant change in TACC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of TACC1. Does perturbing PRDM1 lead to a significant change in TACC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6001
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and SOX5 expression is observed. Does this perturbation lead to a significant difference in SOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and SOX5 expression is observed. Does this perturbation lead to a significant difference in SOX5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2473
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is quantified. Does this perturbation result in a significant change in RP3-525N10.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and RP3-525N10.2 expression is quantified. Does this perturbation result in a significant change in RP3-525N10.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5892
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor GIPR expression. Decide whether this perturbation leads to a significant alteration in GIPR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NIT1 and monitor GIPR expression. Decide whether this perturbation leads to a significant alteration in GIPR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5358
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in FABP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BPGM is associated with a significant change in FABP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3725
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor CRYM expression. Decide whether this perturbation leads to a significant alteration in CRYM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2068
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA2 expression is observed. Does this perturbation lead to a significant difference in ANXA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA2 expression is observed. Does this perturbation lead to a significant difference in ANXA2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2833
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIPK1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of HIPK1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3227
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor CDC20 expression. Decide whether this perturbation leads to a significant alteration in CDC20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1818
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ACTC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ACTC1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5377
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in NBR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4275
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of TFRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL2A1, does the expression profile of TFRC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1227
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Does this perturbation cause a significant change in CLTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Does this perturbation cause a significant change in CLTA expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3990
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and DYNLT3 expression is quantified. Does this perturbation result in a significant change in DYNLT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and DYNLT3 expression is quantified. Does this perturbation result in a significant change in DYNLT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2672
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SKAP1 expression is quantified. Does this perturbation result in a significant change in SKAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and SKAP1 expression is quantified. Does this perturbation result in a significant change in SKAP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":712
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ITGA3 expression is observed. Does this perturbation lead to a significant difference in ITGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and ITGA3 expression is observed. Does this perturbation lead to a significant difference in ITGA3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4133
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3377
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CTD-2378E12.1. Does perturbing CDKN1C lead to a significant change in CTD-2378E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of CTD-2378E12.1. Does perturbing CDKN1C lead to a significant change in CTD-2378E12.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6271
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Determine whether HBG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Determine whether HBG1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5386
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ATF6B expression is measured. Determine whether ATF6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ATF6B expression is measured. Determine whether ATF6B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5329
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and RP11-91A18.4 expression is observed. Does this perturbation lead to a significant difference in RP11-91A18.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and RP11-91A18.4 expression is observed. Does this perturbation lead to a significant difference in RP11-91A18.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2693
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Determine whether CHI3L2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":906
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Does this perturbation cause a significant change in FCGR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of FCGR3A is measured. Does this perturbation cause a significant change in FCGR3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5600
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Determine whether PHLDA2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4766
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Does this perturbation cause a significant change in RNF168 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of RNF168 is measured. Does this perturbation cause a significant change in RNF168 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":770
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in SPARC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in SPARC expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5525
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCDC148 expression is quantified. Does this perturbation result in a significant change in CCDC148 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCDC148 expression is quantified. Does this perturbation result in a significant change in CCDC148 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2132
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of RP11-195C7.1. Does this perturbation cause a significant change in RP11-195C7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HES7 and then measure expression of RP11-195C7.1. Does this perturbation cause a significant change in RP11-195C7.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1734
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Determine whether HCAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, STIL is perturbed and the expression of HCAR2 is measured. Determine whether HCAR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5196
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in IGHEP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB1 is associated with a significant change in IGHEP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3585
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4049
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB1 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3560
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCDC148 expression. Decide whether this perturbation leads to a significant alteration in CCDC148 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor CCDC148 expression. Decide whether this perturbation leads to a significant alteration in CCDC148 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2138
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor KRT7 expression. Decide whether this perturbation leads to a significant alteration in KRT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor KRT7 expression. Decide whether this perturbation leads to a significant alteration in KRT7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2798
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and HBD expression is observed. Does this perturbation lead to a significant difference in HBD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5103
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of APOL6. Does this perturbation cause a significant change in APOL6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL1A1 and then measure expression of APOL6. Does this perturbation cause a significant change in APOL6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3424
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and THBS1 expression is quantified. Does this perturbation result in a significant change in THBS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3212
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and STAC3 expression is quantified. Does this perturbation result in a significant change in STAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and STAC3 expression is quantified. Does this perturbation result in a significant change in STAC3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":272
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of CD24 is measured. Does this perturbation cause a significant change in CD24 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3730
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of DYNLT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of DYNLT3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2677
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RP11-308D13.3 expression is observed. Does this perturbation lead to a significant difference in RP11-308D13.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and RP11-308D13.3 expression is observed. Does this perturbation lead to a significant difference in RP11-308D13.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":763
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Determine whether LINC01358 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of LINC01358 is measured. Determine whether LINC01358 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5616
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of SOCS1 is measured. Determine whether SOCS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4086
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Determine whether RP11-510J16.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC4A1 is perturbed and the expression of RP11-510J16.5 is measured. Determine whether RP11-510J16.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1066
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and RP11-355B11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-355B11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and RP11-355B11.2 expression is observed. Does this perturbation lead to a significant difference in RP11-355B11.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1173
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor HBG1 expression. Decide whether this perturbation leads to a significant alteration in HBG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor HBG1 expression. Decide whether this perturbation leads to a significant alteration in HBG1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5388
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of TNFRSF12A. Does this perturbation cause a significant change in TNFRSF12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LYL1 and then measure expression of TNFRSF12A. Does this perturbation cause a significant change in TNFRSF12A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3904
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLAUR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CBL is associated with a significant change in PLAUR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":735
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Does this perturbation cause a significant change in RBM5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of RBM5-AS1 is measured. Does this perturbation cause a significant change in RBM5-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":160
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RP11-320G24.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-320G24.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor RP11-320G24.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-320G24.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5068
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and WBP2 expression is observed. Does this perturbation lead to a significant difference in WBP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5163
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor SLC8A1 expression. Decide whether this perturbation leads to a significant alteration in SLC8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor SLC8A1 expression. Decide whether this perturbation leads to a significant alteration in SLC8A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4558
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4958
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ASIC4. Does this perturbation cause a significant change in ASIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of ASIC4. Does this perturbation cause a significant change in ASIC4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2244
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1169
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CDK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in CDK1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4405
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is measured. Determine whether RP11-244F12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and RP11-244F12.2 expression is measured. Determine whether RP11-244F12.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4539
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CTD-2012K14.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in CTD-2012K14.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5215
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCORL1 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":376
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ORAI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in ORAI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1945
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of STRC. Does perturbing HOXA13 lead to a significant change in STRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of STRC. Does perturbing HOXA13 lead to a significant change in STRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5901
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of CST3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":977
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ADD3 expression is observed. Does this perturbation lead to a significant difference in ADD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C19orf26 is perturbed and ADD3 expression is observed. Does this perturbation lead to a significant difference in ADD3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2903
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and RPS6KA2 expression is measured. Determine whether RPS6KA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and RPS6KA2 expression is measured. Determine whether RPS6KA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1609
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in INADL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in INADL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2255
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ZMAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in ZMAT3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5135
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAML2 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":69
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CDC20. Does this perturbation cause a significant change in CDC20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5404
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Determine whether TUBB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of TUBB is measured. Determine whether TUBB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2646
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of FAM19A2. Does this perturbation cause a significant change in FAM19A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of FAM19A2. Does this perturbation cause a significant change in FAM19A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3364
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor FABP5 expression. Decide whether this perturbation leads to a significant alteration in FABP5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4328
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2884
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of CDC20. Does perturbing FOXO4 lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of CDC20. Does perturbing FOXO4 lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1811
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3910
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2743
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3B is perturbed and CTB-161C1.1 expression is observed. Does this perturbation lead to a significant difference in CTB-161C1.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1413
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of TMEM88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of TMEM88 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5187
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Does this perturbation cause a significant change in FAM19A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Does this perturbation cause a significant change in FAM19A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3360
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Determine whether PAQR7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":996
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Determine whether PSMB8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of PSMB8 is measured. Determine whether PSMB8 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":106
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of MYO1F. Does this perturbation cause a significant change in MYO1F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of MYO1F. Does this perturbation cause a significant change in MYO1F expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1514
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5263
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2126
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and AC020571.3 expression is measured. Determine whether AC020571.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and AC020571.3 expression is measured. Determine whether AC020571.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1219
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and ID3 expression is measured. Determine whether ID3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":249
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of TRIM22 is measured. Does this perturbation cause a significant change in TRIM22 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4590
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor YPEL3 expression. Decide whether this perturbation leads to a significant alteration in YPEL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN9 and monitor YPEL3 expression. Decide whether this perturbation leads to a significant alteration in YPEL3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5758
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ALAS2 is measured. Does this perturbation cause a significant change in ALAS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3500
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of UBASH3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4807
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of CD24. Does this perturbation cause a significant change in CD24 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3734
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TUBA1A expression. Decide whether this perturbation leads to a significant alteration in TUBA1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP7D1 and monitor TUBA1A expression. Decide whether this perturbation leads to a significant alteration in TUBA1A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2718
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of HIST1H4H. Does this perturbation cause a significant change in HIST1H4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of HIST1H4H. Does this perturbation cause a significant change in HIST1H4H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4344
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CDC45 is measured. Determine whether CDC45 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6246
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTC-492K19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of CTC-492K19.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1127
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ZMYND15 expression is quantified. Does this perturbation result in a significant change in ZMYND15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and ZMYND15 expression is quantified. Does this perturbation result in a significant change in ZMYND15 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2732
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Determine whether TTC9B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of TTC9B is measured. Determine whether TTC9B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4496
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor PRKCB expression. Decide whether this perturbation leads to a significant alteration in PRKCB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3798
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of UCKL1-AS1. Does perturbing CEBPB lead to a significant change in UCKL1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPB and examine the expression of UCKL1-AS1. Does perturbing CEBPB lead to a significant change in UCKL1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5251
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in SAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2885
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5154
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and CSRNP1 expression is measured. Determine whether CSRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and CSRNP1 expression is measured. Determine whether CSRNP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4649
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and CALY expression is quantified. Does this perturbation result in a significant change in CALY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and CALY expression is quantified. Does this perturbation result in a significant change in CALY expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1592
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5168
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of DPYSL2. Does this perturbation cause a significant change in DPYSL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of DPYSL2. Does this perturbation cause a significant change in DPYSL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5804
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of DSC1. Does perturbing ZBTB25 lead to a significant change in DSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of DSC1. Does perturbing ZBTB25 lead to a significant change in DSC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1291
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Does this perturbation cause a significant change in CD59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of CD59 is measured. Does this perturbation cause a significant change in CD59 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2370
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RUNX1T1 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1935
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and PSMB8 expression is quantified. Does this perturbation result in a significant change in PSMB8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAML2 is perturbed and PSMB8 expression is quantified. Does this perturbation result in a significant change in PSMB8 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":102
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1956
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in RP11-244F12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TMSB4X is associated with a significant change in RP11-244F12.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4535
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and HMOX1 expression is observed. Does this perturbation lead to a significant difference in HMOX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and HMOX1 expression is observed. Does this perturbation lead to a significant difference in HMOX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5973
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of CLTA. Does this perturbation cause a significant change in CLTA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of CLTA. Does this perturbation cause a significant change in CLTA expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3994
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is measured. Determine whether RP11-362K14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is measured. Determine whether RP11-362K14.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4189
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IRF1 is perturbed and the expression of AFMID is measured. Determine whether AFMID shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2966
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LINC01562 expression. Decide whether this perturbation leads to a significant alteration in LINC01562 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB25 and monitor LINC01562 expression. Decide whether this perturbation leads to a significant alteration in LINC01562 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1318
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PHLDA2 expression. Decide whether this perturbation leads to a significant alteration in PHLDA2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4768
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2045
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Determine whether RP11-286H15.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of RP11-286H15.1 is measured. Determine whether RP11-286H15.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2516
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MS4A3. Does perturbing LHX1 lead to a significant change in MS4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of MS4A3. Does perturbing LHX1 lead to a significant change in MS4A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":981
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CARMN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CARMN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3277
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1394
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3062
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Does this perturbation cause a significant change in DYNLT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of DYNLT3 is measured. Does this perturbation cause a significant change in DYNLT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2670
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in AIF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6055
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor KCNQ1-AS1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SPI1 and monitor KCNQ1-AS1 expression. Decide whether this perturbation leads to a significant alteration in KCNQ1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5118
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of ZFP36L2. Does this perturbation cause a significant change in ZFP36L2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3674
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ACSL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in ACSL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2775
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HCN1 expression is measured. Determine whether HCN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and HCN1 expression is measured. Determine whether HCN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3049
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-505P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and RP11-505P4.7 expression is quantified. Does this perturbation result in a significant change in RP11-505P4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2552
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and HIST1H2AC expression is observed. Does this perturbation lead to a significant difference in HIST1H2AC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3183
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1643
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Does this perturbation cause a significant change in KCNH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of KCNH2 is measured. Does this perturbation cause a significant change in KCNH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3440
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and AIF1 expression is measured. Determine whether AIF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2289
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4984
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP3-510H16.3. Does this perturbation cause a significant change in RP3-510H16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of RP3-510H16.3. Does this perturbation cause a significant change in RP3-510H16.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3834
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of DYNLL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of DYNLL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2817
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RP5-1142A6.2 is measured. Does this perturbation cause a significant change in RP5-1142A6.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4710
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SLC6A9 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1456
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and TSC22D4 expression is measured. Determine whether TSC22D4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":199
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Does this perturbation cause a significant change in RP11-345P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of RP11-345P4.7 is measured. Does this perturbation cause a significant change in RP11-345P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2870
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and DCAF13 expression is observed. Does this perturbation lead to a significant difference in DCAF13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and DCAF13 expression is observed. Does this perturbation lead to a significant difference in DCAF13 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3543
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of UBASH3A. Does this perturbation cause a significant change in UBASH3A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1954
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and PHLDA2 expression is quantified. Does this perturbation result in a significant change in PHLDA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4762
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TBX3 is perturbed and PIM2 expression is quantified. Does this perturbation result in a significant change in PIM2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":912
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor NKG7 expression. Decide whether this perturbation leads to a significant alteration in NKG7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1388
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of RNF213 is measured. Determine whether RNF213 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5026
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Determine whether SEMA3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of SEMA3B is measured. Determine whether SEMA3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4246
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor LINC01338 expression. Decide whether this perturbation leads to a significant alteration in LINC01338 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor LINC01338 expression. Decide whether this perturbation leads to a significant alteration in LINC01338 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5078
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and HEMGN expression is measured. Determine whether HEMGN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1929
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1648
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":250
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and SH3BGRL expression is measured. Determine whether SH3BGRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCORL1 is perturbed and SH3BGRL expression is measured. Determine whether SH3BGRL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":399
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in S100A4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in S100A4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1045
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TPP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1577
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ABCA6 expression is measured. Determine whether ABCA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and ABCA6 expression is measured. Determine whether ABCA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4179
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of GCM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of GCM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1357
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Determine whether ARMCX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of ARMCX3 is measured. Determine whether ARMCX3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3976
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and TOR3A expression is measured. Determine whether TOR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and TOR3A expression is measured. Determine whether TOR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5349
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and FAM46C expression is quantified. Does this perturbation result in a significant change in FAM46C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C19orf26 is perturbed and FAM46C expression is quantified. Does this perturbation result in a significant change in FAM46C expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2892
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and TACC1 expression is quantified. Does this perturbation result in a significant change in TACC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and TACC1 expression is quantified. Does this perturbation result in a significant change in TACC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6002
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and CNN2 expression is observed. Does this perturbation lead to a significant difference in CNN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and CNN2 expression is observed. Does this perturbation lead to a significant difference in CNN2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4703
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and INADL expression is measured. Determine whether INADL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and INADL expression is measured. Determine whether INADL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2259
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in RUNX1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2785
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in FCGR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in FCGR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5605
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIST1H2AC expression. Decide whether this perturbation leads to a significant alteration in HIST1H2AC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3188
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TPP1. Does this perturbation cause a significant change in TPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TPP1. Does this perturbation cause a significant change in TPP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1574
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in CCDC136 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of OSR2 is associated with a significant change in CCDC136 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5035
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Does this perturbation cause a significant change in H1FNT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C19orf26 is perturbed and the expression of H1FNT is measured. Does this perturbation cause a significant change in H1FNT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2910
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARRDC3 and then measure expression of PRKCB. Does this perturbation cause a significant change in PRKCB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3794
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of RP11-244F12.2. Does perturbing TMSB4X lead to a significant change in RP11-244F12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of RP11-244F12.2. Does perturbing TMSB4X lead to a significant change in RP11-244F12.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4531
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of AC006262.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":497
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and PAQR7 expression is quantified. Does this perturbation result in a significant change in PAQR7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1182
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of DDX58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of DDX58 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":227
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Does this perturbation cause a significant change in UNC5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CLDN6 is perturbed and the expression of UNC5B is measured. Does this perturbation cause a significant change in UNC5B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3250
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of RP11-91A18.4. Does perturbing TP73 lead to a significant change in RP11-91A18.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TP73 and examine the expression of RP11-91A18.4. Does perturbing TP73 lead to a significant change in RP11-91A18.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2691
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SOCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in SOCS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":695
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Determine whether INHBE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of INHBE is measured. Determine whether INHBE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5786
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of AC004540.4. Does perturbing FOXL2 lead to a significant change in AC004540.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of AC004540.4. Does perturbing FOXL2 lead to a significant change in AC004540.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4121
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and RAB5B expression is quantified. Does this perturbation result in a significant change in RAB5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and RAB5B expression is quantified. Does this perturbation result in a significant change in RAB5B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":682
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which POU3F2 is perturbed and FABP5 expression is observed. Does this perturbation lead to a significant difference in FABP5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2053
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor MYB expression. Decide whether this perturbation leads to a significant alteration in MYB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNN1 and monitor MYB expression. Decide whether this perturbation leads to a significant alteration in MYB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2108
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and LGALS1 expression is quantified. Does this perturbation result in a significant change in LGALS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4632
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6113
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Determine whether RP11-505P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Determine whether RP11-505P4.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2556
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IKZF3, does the expression profile of AVP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3007
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of PKIG. Does this perturbation cause a significant change in PKIG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of PKIG. Does this perturbation cause a significant change in PKIG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":204
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Does this perturbation cause a significant change in PPP4R4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF2C is perturbed and the expression of PPP4R4 is measured. Does this perturbation cause a significant change in PPP4R4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4610
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of LINC01003. Does perturbing MEIS1 lead to a significant change in LINC01003 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of LINC01003. Does perturbing MEIS1 lead to a significant change in LINC01003 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":451
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Determine whether ZMYND15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of ZMYND15 is measured. Determine whether ZMYND15 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2736
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor ZNF467 expression. Decide whether this perturbation leads to a significant alteration in ZNF467 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6138
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5983
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HCN1 expression is observed. Does this perturbation lead to a significant difference in HCN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and HCN1 expression is observed. Does this perturbation lead to a significant difference in HCN1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3043
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SOCS2. Does this perturbation cause a significant change in SOCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SOCS2. Does this perturbation cause a significant change in SOCS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":694
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Does this perturbation cause a significant change in C1orf162 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of C1orf162 is measured. Does this perturbation cause a significant change in C1orf162 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3530
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of SLC8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of SLC8A1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4557
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of RIMBP3C. Does this perturbation cause a significant change in RIMBP3C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of RIMBP3C. Does this perturbation cause a significant change in RIMBP3C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3284
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of NCKAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3087
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of HBD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5107
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Does this perturbation cause a significant change in IL1RN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CELF2 is perturbed and the expression of IL1RN is measured. Does this perturbation cause a significant change in IL1RN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2190
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CSRNP1, does the expression profile of ZNF431 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4677
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Does this perturbation cause a significant change in CSRNP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of CSRNP1 is measured. Does this perturbation cause a significant change in CSRNP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4640
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ARHGEF6 expression is measured. Determine whether ARHGEF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and ARHGEF6 expression is measured. Determine whether ARHGEF6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2119
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4523
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor MKNK2 expression. Decide whether this perturbation leads to a significant alteration in MKNK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor MKNK2 expression. Decide whether this perturbation leads to a significant alteration in MKNK2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1628
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCM2L expression is quantified. Does this perturbation result in a significant change in CCM2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and CCM2L expression is quantified. Does this perturbation result in a significant change in CCM2L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2142
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of RP11-635N19.1. Does perturbing MAP4K5 lead to a significant change in RP11-635N19.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of RP11-635N19.1. Does perturbing MAP4K5 lead to a significant change in RP11-635N19.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1371
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in FAM46C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in FAM46C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2895
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb STIL and monitor PYROXD2 expression. Decide whether this perturbation leads to a significant alteration in PYROXD2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5158
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of AC004051.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of AC004051.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1847
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and CDC20 expression is observed. Does this perturbation lead to a significant difference in CDC20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1813
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of HBD is measured. Does this perturbation cause a significant change in HBD expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5100
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-567N4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in RP11-567N4.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1785
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ADGB. Does this perturbation cause a significant change in ADGB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of ADGB. Does this perturbation cause a significant change in ADGB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5544
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLAUR expression. Decide whether this perturbation leads to a significant alteration in PLAUR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor PLAUR expression. Decide whether this perturbation leads to a significant alteration in PLAUR expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":738
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of HBD. Does perturbing SPI1 lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of HBD. Does perturbing SPI1 lead to a significant change in HBD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5101
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is quantified. Does this perturbation result in a significant change in CTA-384D8.34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and CTA-384D8.34 expression is quantified. Does this perturbation result in a significant change in CTA-384D8.34 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":642
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of RP1-59D14.10. Does this perturbation cause a significant change in RP1-59D14.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BPGM and then measure expression of RP1-59D14.10. Does this perturbation cause a significant change in RP1-59D14.10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3774
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Determine whether STAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of STAC3 is measured. Determine whether STAC3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":276
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor FCGR3A expression. Decide whether this perturbation leads to a significant alteration in FCGR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor FCGR3A expression. Decide whether this perturbation leads to a significant alteration in FCGR3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5608
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ANTXR2 expression is measured. Determine whether ANTXR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and ANTXR2 expression is measured. Determine whether ANTXR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5589
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Does this perturbation cause a significant change in ETS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of ETS1 is measured. Does this perturbation cause a significant change in ETS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":580
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in RIMBP3C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in RIMBP3C expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3285
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is quantified. Does this perturbation result in a significant change in SLC2A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and SLC2A1-AS1 expression is quantified. Does this perturbation result in a significant change in SLC2A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1992
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor AC144568.2 expression. Decide whether this perturbation leads to a significant alteration in AC144568.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KLF1 and monitor AC144568.2 expression. Decide whether this perturbation leads to a significant alteration in AC144568.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":598
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Determine whether TRPM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of TRPM2 is measured. Determine whether TRPM2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1426
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of SH3RF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CKS1B, does the expression profile of SH3RF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3237
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and INHBE expression is observed. Does this perturbation lead to a significant difference in INHBE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and INHBE expression is observed. Does this perturbation lead to a significant difference in INHBE expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5783
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of C10orf11 is measured. Does this perturbation cause a significant change in C10orf11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4960
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and RP11-714G18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-714G18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXO4 is perturbed and RP11-714G18.1 expression is observed. Does this perturbation lead to a significant difference in RP11-714G18.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1853
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Determine whether CLTA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of CLTA is measured. Determine whether CLTA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3996
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of BCL2L11. Does perturbing BCL2L11 lead to a significant change in BCL2L11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCL2L11 and examine the expression of BCL2L11. Does perturbing BCL2L11 lead to a significant change in BCL2L11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4921
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of AC004540.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of AC004540.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4127
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of IGFL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of IGFL2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5497
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and ALAS2 expression is quantified. Does this perturbation result in a significant change in ALAS2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6232
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in CFH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5445
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and AC004051.2 expression is quantified. Does this perturbation result in a significant change in AC004051.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and AC004051.2 expression is quantified. Does this perturbation result in a significant change in AC004051.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1842
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor EGOT expression. Decide whether this perturbation leads to a significant alteration in EGOT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor EGOT expression. Decide whether this perturbation leads to a significant alteration in EGOT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5678
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ATP8B4 expression. Decide whether this perturbation leads to a significant alteration in ATP8B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor ATP8B4 expression. Decide whether this perturbation leads to a significant alteration in ATP8B4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1558
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Determine whether STRA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of STRA6 is measured. Determine whether STRA6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":656
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5269
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Does this perturbation cause a significant change in RP11-505P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-505P4.7 is measured. Does this perturbation cause a significant change in RP11-505P4.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2550
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1938
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN9 is associated with a significant change in PIM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5745
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of SIGLEC15. Does this perturbation cause a significant change in SIGLEC15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of SIGLEC15. Does this perturbation cause a significant change in SIGLEC15 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1964
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LRRC74B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LRRC74B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4655
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of ZNF467 is measured. Determine whether ZNF467 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":876
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in PYROXD2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2225
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":559
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is measured. Determine whether CTD-2616J11.16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZNF318 is perturbed and CTD-2616J11.16 expression is measured. Determine whether CTD-2616J11.16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1199
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor HIST1H4H expression. Decide whether this perturbation leads to a significant alteration in HIST1H4H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor HIST1H4H expression. Decide whether this perturbation leads to a significant alteration in HIST1H4H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4348
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4765
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of ZEB2 is measured. Does this perturbation cause a significant change in ZEB2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3200
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ATG2A. Does this perturbation cause a significant change in ATG2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of ATG2A. Does this perturbation cause a significant change in ATG2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3634
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Does this perturbation cause a significant change in RP11-83A24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, GLB1L2 is perturbed and the expression of RP11-83A24.2 is measured. Does this perturbation cause a significant change in RP11-83A24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":520
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Determine whether DCAF13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of DCAF13 is measured. Determine whether DCAF13 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3546
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-567N4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-567N4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-567N4.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-567N4.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1788
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ICAM4 expression. Decide whether this perturbation leads to a significant alteration in ICAM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor ICAM4 expression. Decide whether this perturbation leads to a significant alteration in ICAM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4748
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM118A expression is measured. Determine whether FAM118A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and FAM118A expression is measured. Determine whether FAM118A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2669
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PRTG is perturbed and AC016629.3 expression is measured. Determine whether AC016629.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3619
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor SAT2 expression. Decide whether this perturbation leads to a significant alteration in SAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2888
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor CTSS expression. Decide whether this perturbation leads to a significant alteration in CTSS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor CTSS expression. Decide whether this perturbation leads to a significant alteration in CTSS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2028
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RNF213. Does perturbing TSC22D1 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TSC22D1 and examine the expression of RNF213. Does perturbing TSC22D1 lead to a significant change in RNF213 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":21
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ATP9A expression is quantified. Does this perturbation result in a significant change in ATP9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ATP9A expression is quantified. Does this perturbation result in a significant change in ATP9A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":532
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTD-3037G24.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTD-3037G24.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1437
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and ZEB2 expression is measured. Determine whether ZEB2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3209
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in AC007556.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ETS2 is associated with a significant change in AC007556.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":825
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Does this perturbation cause a significant change in ATP8B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of ATP8B4 is measured. Does this perturbation cause a significant change in ATP8B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1550
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4163
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ATP9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in ATP9A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":535
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-219B4.7 expression is quantified. Does this perturbation result in a significant change in RP11-219B4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-219B4.7 expression is quantified. Does this perturbation result in a significant change in RP11-219B4.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1772
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of CRABP2. Does perturbing ELMSAN1 lead to a significant change in CRABP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of CRABP2. Does perturbing ELMSAN1 lead to a significant change in CRABP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":281
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CMB9-22P13.1. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of CMB9-22P13.1. Does this perturbation cause a significant change in CMB9-22P13.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5394
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Determine whether RP11-362K14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Determine whether RP11-362K14.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4186
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1158
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of AC064834.2. Does perturbing PTPN1 lead to a significant change in AC064834.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of AC064834.2. Does perturbing PTPN1 lead to a significant change in AC064834.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2441
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3018
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TSC22D1 is perturbed and the expression of RP1-34B20.21 is measured. Determine whether RP1-34B20.21 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PCDHGA6. Does this perturbation cause a significant change in PCDHGA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB25 and then measure expression of PCDHGA6. Does this perturbation cause a significant change in PCDHGA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1304
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1A is perturbed and DST expression is quantified. Does this perturbation result in a significant change in DST expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2342
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and EMP3 expression is observed. Does this perturbation lead to a significant difference in EMP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and EMP3 expression is observed. Does this perturbation lead to a significant difference in EMP3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3033
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in PLEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in PLEK expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5095
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CHI3L2. Does perturbing PRDM1 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRDM1 and examine the expression of CHI3L2. Does perturbing PRDM1 lead to a significant change in CHI3L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5981
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CTD-2311M21.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2311M21.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCORL1 and monitor CTD-2311M21.3 expression. Decide whether this perturbation leads to a significant alteration in CTD-2311M21.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":408
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RPL17-C18orf32 expression is observed. Does this perturbation lead to a significant difference in RPL17-C18orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and RPL17-C18orf32 expression is observed. Does this perturbation lead to a significant difference in RPL17-C18orf32 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5773
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is measured. Determine whether RP11-180M15.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is measured. Determine whether RP11-180M15.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4439
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CTD-2031P19.5 expression is observed. Does this perturbation lead to a significant difference in CTD-2031P19.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CTD-2031P19.5 expression is observed. Does this perturbation lead to a significant difference in CTD-2031P19.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":883
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and CPVL expression is observed. Does this perturbation lead to a significant difference in CPVL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and CPVL expression is observed. Does this perturbation lead to a significant difference in CPVL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4933
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor HEMGN expression. Decide whether this perturbation leads to a significant alteration in HEMGN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":258
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and RPS6KA2 expression is quantified. Does this perturbation result in a significant change in RPS6KA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and RPS6KA2 expression is quantified. Does this perturbation result in a significant change in RPS6KA2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1602
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3579
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and SLC31A2 expression is measured. Determine whether SLC31A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and SLC31A2 expression is measured. Determine whether SLC31A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5419
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP6-159A1.4 expression is observed. Does this perturbation lead to a significant difference in RP6-159A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and RP6-159A1.4 expression is observed. Does this perturbation lead to a significant difference in RP6-159A1.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2823
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-497G19.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-497G19.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb COL2A1 and monitor RP11-497G19.7 expression. Decide whether this perturbation leads to a significant alteration in RP11-497G19.7 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1258
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is measured. Determine whether CTD-3126B10.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CTD-3126B10.4 expression is measured. Determine whether CTD-3126B10.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2399
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNNM4, does the expression profile of GYPE indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4757
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of COL18A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of COL18A1-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":637
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SOCS2 expression is measured. Determine whether SOCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SOCS2 expression is measured. Determine whether SOCS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":699
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of HCAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of STIL, does the expression profile of HCAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5197
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of PRKCB. Does perturbing CSRNP1 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of PRKCB. Does perturbing CSRNP1 lead to a significant change in PRKCB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4621
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in HIST1H4H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in HIST1H4H expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4345
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and MKNK2 expression is observed. Does this perturbation lead to a significant difference in MKNK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBFA2T3 is perturbed and MKNK2 expression is observed. Does this perturbation lead to a significant difference in MKNK2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1623
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3787
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RP3-467K16.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-467K16.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1478
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXA3, does the expression profile of LST1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3327
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1959
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of VCX3B. Does this perturbation cause a significant change in VCX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of VCX3B. Does this perturbation cause a significant change in VCX3B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":154
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of UBE2H. Does this perturbation cause a significant change in UBE2H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2364
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CTD-3126B10.4. Does perturbing CDKN1A lead to a significant change in CTD-3126B10.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1A and examine the expression of CTD-3126B10.4. Does perturbing CDKN1A lead to a significant change in CTD-3126B10.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2391
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of FCER1G indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4447
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of LPAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of LPAR2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3107
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor TDRD12 expression. Decide whether this perturbation leads to a significant alteration in TDRD12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor TDRD12 expression. Decide whether this perturbation leads to a significant alteration in TDRD12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":98
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of COL1A1. Does this perturbation cause a significant change in COL1A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to OSR2 and then measure expression of COL1A1. Does this perturbation cause a significant change in COL1A1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5054
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLA2G1B expression is observed. Does this perturbation lead to a significant difference in PLA2G1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CBL is perturbed and PLA2G1B expression is observed. Does this perturbation lead to a significant difference in PLA2G1B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":753
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in SLC4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in SLC4A3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6085
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CCNB1 expression is observed. Does this perturbation lead to a significant difference in CCNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and CCNB1 expression is observed. Does this perturbation lead to a significant difference in CCNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3853
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of CD24. Does perturbing ZBTB1 lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of CD24. Does perturbing ZBTB1 lead to a significant change in CD24 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3571
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Does this perturbation cause a significant change in MKNK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBFA2T3 is perturbed and the expression of MKNK2 is measured. Does this perturbation cause a significant change in MKNK2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1620
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Determine whether RUNDC3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of RUNDC3B is measured. Determine whether RUNDC3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2806
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and LBH expression is observed. Does this perturbation lead to a significant difference in LBH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and LBH expression is observed. Does this perturbation lead to a significant difference in LBH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5933
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Does this perturbation cause a significant change in C1orf141 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Does this perturbation cause a significant change in C1orf141 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2330
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and IER3 expression is observed. Does this perturbation lead to a significant difference in IER3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and IER3 expression is observed. Does this perturbation lead to a significant difference in IER3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2763
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of TYROBP indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":797
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and N4BP2L2 expression is observed. Does this perturbation lead to a significant difference in N4BP2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and N4BP2L2 expression is observed. Does this perturbation lead to a significant difference in N4BP2L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4223
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of HEMGN. Does perturbing RUNX1T1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of HEMGN. Does perturbing RUNX1T1 lead to a significant change in HEMGN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1921
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RABGAP1L. Does perturbing GLB1L2 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of RABGAP1L. Does perturbing GLB1L2 lead to a significant change in RABGAP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":481
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TPM4. Does perturbing TMSB4X lead to a significant change in TPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of TPM4. Does perturbing TMSB4X lead to a significant change in TPM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4511
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is quantified. Does this perturbation result in a significant change in TM4SF1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and TM4SF1-AS1 expression is quantified. Does this perturbation result in a significant change in TM4SF1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3752
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6114
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Does this perturbation cause a significant change in RP11-52L5.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-52L5.6 is measured. Does this perturbation cause a significant change in RP11-52L5.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6200
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and ZNF431 expression is quantified. Does this perturbation result in a significant change in ZNF431 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4672
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor SLC4A3 expression. Decide whether this perturbation leads to a significant alteration in SLC4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor SLC4A3 expression. Decide whether this perturbation leads to a significant alteration in SLC4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6088
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of PROX1. Does this perturbation cause a significant change in PROX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of PROX1. Does this perturbation cause a significant change in PROX1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4054
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and BAK1 expression is measured. Determine whether BAK1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":629
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and IFIT2 expression is quantified. Does this perturbation result in a significant change in IFIT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and IFIT2 expression is quantified. Does this perturbation result in a significant change in IFIT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6022
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of GYPE is measured. Determine whether GYPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4756
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IRF1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2985
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor FNDC3A expression. Decide whether this perturbation leads to a significant alteration in FNDC3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor FNDC3A expression. Decide whether this perturbation leads to a significant alteration in FNDC3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4588
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor AC004540.4 expression. Decide whether this perturbation leads to a significant alteration in AC004540.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor AC004540.4 expression. Decide whether this perturbation leads to a significant alteration in AC004540.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4128
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":125
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of DLX4. Does perturbing EGR1 lead to a significant change in DLX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of DLX4. Does perturbing EGR1 lead to a significant change in DLX4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6161
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Determine whether ATG2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Determine whether ATG2A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3636
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF2C and then measure expression of TRIM22. Does this perturbation cause a significant change in TRIM22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4594
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and SLC8A1 expression is observed. Does this perturbation lead to a significant difference in SLC8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and SLC8A1 expression is observed. Does this perturbation lead to a significant difference in SLC8A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4553
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of TUBB2B. Does this perturbation cause a significant change in TUBB2B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1584
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of VGF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of VGF indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":267
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AP1S2 is measured. Determine whether AP1S2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4266
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CYP3A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in CYP3A5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":865
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor C1orf141 expression. Decide whether this perturbation leads to a significant alteration in C1orf141 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor C1orf141 expression. Decide whether this perturbation leads to a significant alteration in C1orf141 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2338
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP7D1 is perturbed and CST3 expression is measured. Determine whether CST3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2749
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of AC007556.3. Does this perturbation cause a significant change in AC007556.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of AC007556.3. Does this perturbation cause a significant change in AC007556.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":824
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RP11-83A24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of RP11-83A24.2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":527
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is quantified. Does this perturbation result in a significant change in RP11-83A24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RP11-83A24.2 expression is quantified. Does this perturbation result in a significant change in RP11-83A24.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":522
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in C1orf162 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in C1orf162 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3535
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCDC148. Does this perturbation cause a significant change in CCDC148 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CNN1 and then measure expression of CCDC148. Does this perturbation cause a significant change in CCDC148 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2134
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Determine whether RP11-244F12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Determine whether RP11-244F12.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4536
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RHOH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in RHOH expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4455
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Does this perturbation cause a significant change in TPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Does this perturbation cause a significant change in TPM4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4510
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Does this perturbation cause a significant change in HHEX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Does this perturbation cause a significant change in HHEX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3380
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ELMSAN1 is perturbed and HEMGN expression is quantified. Does this perturbation result in a significant change in HEMGN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":252
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Determine whether ZNF85 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of ZNF85 is measured. Determine whether ZNF85 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":516
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Determine whether SLC7A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of SLC7A11 is measured. Determine whether SLC7A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4896
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3326
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Determine whether RP11-445F12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Determine whether RP11-445F12.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":606
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Determine whether TUBA1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP7D1 is perturbed and the expression of TUBA1A is measured. Determine whether TUBA1A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2716
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of MARCKS. Does this perturbation cause a significant change in MARCKS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of MARCKS. Does this perturbation cause a significant change in MARCKS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4994
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RUNX1T1 is perturbed and the expression of BST2 is measured. Determine whether BST2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1936
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of CTB-49A3.5. Does this perturbation cause a significant change in CTB-49A3.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SAMD1 and then measure expression of CTB-49A3.5. Does this perturbation cause a significant change in CTB-49A3.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3394
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NCL is perturbed and ID1 expression is observed. Does this perturbation lead to a significant difference in ID1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4863
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CD46 expression is observed. Does this perturbation lead to a significant difference in CD46 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4203
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARRDC3, does the expression profile of PRKCB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3797
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CREB3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of CREB3L2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5997
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and RP1-102K2.6 expression is observed. Does this perturbation lead to a significant difference in RP1-102K2.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1013
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of ID3 is measured. Determine whether ID3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":246
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is quantified. Does this perturbation result in a significant change in RP11-362K14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and RP11-362K14.7 expression is quantified. Does this perturbation result in a significant change in RP11-362K14.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4182
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Determine whether FLJ12825 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of FLJ12825 is measured. Determine whether FLJ12825 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":176
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of PTPRS. Does this perturbation cause a significant change in PTPRS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of PTPRS. Does this perturbation cause a significant change in PTPRS expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":664
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Does this perturbation cause a significant change in ATF6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Does this perturbation cause a significant change in ATF6B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5320
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in MAOB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in MAOB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1495
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and AC074289.1 expression is quantified. Does this perturbation result in a significant change in AC074289.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1612
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of CCNG2. Does perturbing SGK1 lead to a significant change in CCNG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SGK1 and examine the expression of CCNG2. Does perturbing SGK1 lead to a significant change in CCNG2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4061
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor RP11-244F12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-244F12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TMSB4X and monitor RP11-244F12.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-244F12.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4538
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ID3 is measured. Does this perturbation cause a significant change in ID3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3480
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Determine whether RP11-290L1.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of RP11-290L1.2 is measured. Determine whether RP11-290L1.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2036
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Does this perturbation cause a significant change in CYP2C18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CYP2C18 is measured. Does this perturbation cause a significant change in CYP2C18 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":930
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor DYNLL1 expression. Decide whether this perturbation leads to a significant alteration in DYNLL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOSB and monitor DYNLL1 expression. Decide whether this perturbation leads to a significant alteration in DYNLL1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2818
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PLK4 is associated with a significant change in PNMT expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3665
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor SLCO6A1 expression. Decide whether this perturbation leads to a significant alteration in SLCO6A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KMT2A and monitor SLCO6A1 expression. Decide whether this perturbation leads to a significant alteration in SLCO6A1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4358
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in HBG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in HBG1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5385
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Determine whether RP1-261G23.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Determine whether RP1-261G23.7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1906
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01227 expression is measured. Determine whether LINC01227 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01227 expression is measured. Determine whether LINC01227 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5439
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of STRA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of STRA6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":657
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Determine whether AC004540.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Determine whether AC004540.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4126
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ADGRF1. Does perturbing SLC38A2 lead to a significant change in ADGRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC38A2 and examine the expression of ADGRF1. Does perturbing SLC38A2 lead to a significant change in ADGRF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5721
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ISL2 is associated with a significant change in GIPC2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4485
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of RP11-355B11.2. Does this perturbation cause a significant change in RP11-355B11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of RP11-355B11.2. Does this perturbation cause a significant change in RP11-355B11.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1174
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5819
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and CCDC136 expression is quantified. Does this perturbation result in a significant change in CCDC136 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and CCDC136 expression is quantified. Does this perturbation result in a significant change in CCDC136 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5032
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and SLCO6A1 expression is quantified. Does this perturbation result in a significant change in SLCO6A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and SLCO6A1 expression is quantified. Does this perturbation result in a significant change in SLCO6A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4352
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXL2 and monitor SOCS1 expression. Decide whether this perturbation leads to a significant alteration in SOCS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4088
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of NBR1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4887
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IKZF3 is perturbed and the expression of AVP is measured. Determine whether AVP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3006
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SPANXN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SPANXN5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3467
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Does this perturbation cause a significant change in STRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Does this perturbation cause a significant change in STRC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5900
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Determine whether REEP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, S1PR2 is perturbed and the expression of REEP6 is measured. Determine whether REEP6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2006
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of LBH. Does perturbing CITED1 lead to a significant change in LBH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CITED1 and examine the expression of LBH. Does perturbing CITED1 lead to a significant change in LBH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5931
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of RHOXF2BB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC38A2, does the expression profile of RHOXF2BB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5717
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF18B is perturbed and AMHR2 expression is observed. Does this perturbation lead to a significant difference in AMHR2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6103
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor MOGAT2 expression. Decide whether this perturbation leads to a significant alteration in MOGAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor MOGAT2 expression. Decide whether this perturbation leads to a significant alteration in MOGAT2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5538
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCDC148. Does perturbing CNN1 lead to a significant change in CCDC148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of CCDC148. Does perturbing CNN1 lead to a significant change in CCDC148 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2131
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and TOR3A expression is observed. Does this perturbation lead to a significant difference in TOR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and TOR3A expression is observed. Does this perturbation lead to a significant difference in TOR3A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5343
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and GPR35 expression is quantified. Does this perturbation result in a significant change in GPR35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and GPR35 expression is quantified. Does this perturbation result in a significant change in GPR35 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3922
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and BLVRB expression is measured. Determine whether BLVRB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2129
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":486
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of TPP1 is measured. Does this perturbation cause a significant change in TPP1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1570
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of ALAS2 is measured. Determine whether ALAS2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6236
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ITGA3. Does this perturbation cause a significant change in ITGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of ITGA3. Does this perturbation cause a significant change in ITGA3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4134
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Determine whether RP6-159A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAPK1 is perturbed and the expression of RP6-159A1.4 is measured. Determine whether RP6-159A1.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2826
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of RASGRF2. Does this perturbation cause a significant change in RASGRF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of RASGRF2. Does this perturbation cause a significant change in RASGRF2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1544
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of MME. Does this perturbation cause a significant change in MME expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of MME. Does this perturbation cause a significant change in MME expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6264
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of REEP6. Does this perturbation cause a significant change in REEP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of REEP6. Does this perturbation cause a significant change in REEP6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2004
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ITGA3 expression is quantified. Does this perturbation result in a significant change in ITGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXL2 is perturbed and ITGA3 expression is quantified. Does this perturbation result in a significant change in ITGA3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4132
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ASIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K3 is associated with a significant change in ASIC4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2245
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RP11-308D13.3. Does this perturbation cause a significant change in RP11-308D13.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RP11-308D13.3. Does this perturbation cause a significant change in RP11-308D13.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":764
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of RP11-202A13.1. Does perturbing CNNM4 lead to a significant change in RP11-202A13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of RP11-202A13.1. Does perturbing CNNM4 lead to a significant change in RP11-202A13.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4781
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of SOCS3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3457
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of SAT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3077
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA3 and monitor LST1 expression. Decide whether this perturbation leads to a significant alteration in LST1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3328
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C8orf22 expression is observed. Does this perturbation lead to a significant difference in C8orf22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C8orf22 expression is observed. Does this perturbation lead to a significant difference in C8orf22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1893
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of TNFAIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPB, does the expression profile of TNFAIP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5207
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and FLJ12825 expression is observed. Does this perturbation lead to a significant difference in FLJ12825 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and FLJ12825 expression is observed. Does this perturbation lead to a significant difference in FLJ12825 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":173
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Determine whether CCDC148 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Determine whether CCDC148 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2136
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CTD-2012K14.6 expression is observed. Does this perturbation lead to a significant difference in CTD-2012K14.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPB is perturbed and CTD-2012K14.6 expression is observed. Does this perturbation lead to a significant difference in CTD-2012K14.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5213
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Does this perturbation cause a significant change in PCDHGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of PCDHGA3 is measured. Does this perturbation cause a significant change in PCDHGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2560
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CKS1B is perturbed and HIST1H2AC expression is measured. Determine whether HIST1H2AC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3189
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of TNFRSF12A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of TNFRSF12A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3907
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of CTA-384D8.34. Does this perturbation cause a significant change in CTA-384D8.34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of CTA-384D8.34. Does this perturbation cause a significant change in CTA-384D8.34 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":644
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and AC064834.2 expression is observed. Does this perturbation lead to a significant difference in AC064834.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and AC064834.2 expression is observed. Does this perturbation lead to a significant difference in AC064834.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2443
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RP11-308D13.3 expression is quantified. Does this perturbation result in a significant change in RP11-308D13.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and RP11-308D13.3 expression is quantified. Does this perturbation result in a significant change in RP11-308D13.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":762
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in PHACTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in PHACTR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4385
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6182
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of BST2 is measured. Does this perturbation cause a significant change in BST2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5450
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ABCA13 expression is quantified. Does this perturbation result in a significant change in ABCA13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, POU3F2 is perturbed and ABCA13 expression is quantified. Does this perturbation result in a significant change in ABCA13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2092
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and UBASH3B expression is quantified. Does this perturbation result in a significant change in UBASH3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1402
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN9 is perturbed and FBXL20 expression is observed. Does this perturbation lead to a significant difference in FBXL20 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5763
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of RP11-6D1.3. Does perturbing MAP2K6 lead to a significant change in RP11-6D1.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of RP11-6D1.3. Does perturbing MAP2K6 lead to a significant change in RP11-6D1.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4011
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and NUMB expression is measured. Determine whether NUMB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CLDN6 is perturbed and NUMB expression is measured. Determine whether NUMB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3269
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01420 expression is measured. Determine whether LINC01420 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and LINC01420 expression is measured. Determine whether LINC01420 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5429
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ATF6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of ATF6B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5327
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ACSL1 expression is observed. Does this perturbation lead to a significant difference in ACSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and ACSL1 expression is observed. Does this perturbation lead to a significant difference in ACSL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2773
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4633
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and CHI3L2 expression is observed. Does this perturbation lead to a significant difference in CHI3L2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":903
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in MBP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1005
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CMB9-22P13.1 expression. Decide whether this perturbation leads to a significant alteration in CMB9-22P13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1B and monitor CMB9-22P13.1 expression. Decide whether this perturbation leads to a significant alteration in CMB9-22P13.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5398
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Determine whether HSD17B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Determine whether HSD17B4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":146
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CACNA1C-AS2. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of CACNA1C-AS2. Does this perturbation cause a significant change in CACNA1C-AS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":354
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is quantified. Does this perturbation result in a significant change in CTD-2527I21.14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and CTD-2527I21.14 expression is quantified. Does this perturbation result in a significant change in CTD-2527I21.14 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4412
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is measured. Determine whether RP11-510J16.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and RP11-510J16.5 expression is measured. Determine whether RP11-510J16.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1069
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of IL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of IL20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3767
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ZFP36L2. Does perturbing PLK4 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of ZFP36L2. Does perturbing PLK4 lead to a significant change in ZFP36L2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3671
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of CDC45 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":127
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of SIGLEC15. Does perturbing RUNX1T1 lead to a significant change in SIGLEC15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RUNX1T1 and examine the expression of SIGLEC15. Does perturbing RUNX1T1 lead to a significant change in SIGLEC15 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1961
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of LGALS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3322
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Does this perturbation cause a significant change in ZIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Does this perturbation cause a significant change in ZIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2610
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TPM4. Does this perturbation cause a significant change in TPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of TPM4. Does this perturbation cause a significant change in TPM4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4514
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor VCX3B expression. Decide whether this perturbation leads to a significant alteration in VCX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor VCX3B expression. Decide whether this perturbation leads to a significant alteration in VCX3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":158
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Determine whether GPR35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of GPR35 is measured. Determine whether GPR35 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3926
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2705
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and GCM2 expression is observed. Does this perturbation lead to a significant difference in GCM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and GCM2 expression is observed. Does this perturbation lead to a significant difference in GCM2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1353
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-219B4.7. Does this perturbation cause a significant change in RP11-219B4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to AHR and then measure expression of RP11-219B4.7. Does this perturbation cause a significant change in RP11-219B4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1774
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in LINC00479 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCORL1 is associated with a significant change in LINC00479 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":415
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and H1FNT expression is measured. Determine whether H1FNT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and H1FNT expression is measured. Determine whether H1FNT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2919
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AC034228.4 expression. Decide whether this perturbation leads to a significant alteration in AC034228.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HNF4A and monitor AC034228.4 expression. Decide whether this perturbation leads to a significant alteration in AC034228.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4298
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and FAM49A expression is observed. Does this perturbation lead to a significant difference in FAM49A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and FAM49A expression is observed. Does this perturbation lead to a significant difference in FAM49A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":473
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and RP1-261G23.7 expression is observed. Does this perturbation lead to a significant difference in RP1-261G23.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and RP1-261G23.7 expression is observed. Does this perturbation lead to a significant difference in RP1-261G23.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1903
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor TSC22D4 expression. Decide whether this perturbation leads to a significant alteration in TSC22D4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":198
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor SLC43A2 expression. Decide whether this perturbation leads to a significant alteration in SLC43A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor SLC43A2 expression. Decide whether this perturbation leads to a significant alteration in SLC43A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1538
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and RELB expression is observed. Does this perturbation lead to a significant difference in RELB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and RELB expression is observed. Does this perturbation lead to a significant difference in RELB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5653
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3067
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP3-467K16.2. Does perturbing PLK4 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP3-467K16.2. Does perturbing PLK4 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3711
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ANXA2R expression is quantified. Does this perturbation result in a significant change in ANXA2R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and ANXA2R expression is quantified. Does this perturbation result in a significant change in ANXA2R expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5872
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor RCSD1 expression. Decide whether this perturbation leads to a significant alteration in RCSD1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1448
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RCSD1 is measured. Does this perturbation cause a significant change in RCSD1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1440
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAML2 and monitor CD52 expression. Decide whether this perturbation leads to a significant alteration in CD52 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":88
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, JUN is perturbed and the expression of AFMID is measured. Does this perturbation cause a significant change in AFMID expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5500
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Does this perturbation cause a significant change in MSX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of MSX1 is measured. Does this perturbation cause a significant change in MSX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4030
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXB9 is perturbed and the expression of FABP5 is measured. Does this perturbation cause a significant change in FABP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3060
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of TDRD12. Does this perturbation cause a significant change in TDRD12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of TDRD12. Does this perturbation cause a significant change in TDRD12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":94
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of SSTR3. Does this perturbation cause a significant change in SSTR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of SSTR3. Does this perturbation cause a significant change in SSTR3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3174
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and FCGR2A expression is quantified. Does this perturbation result in a significant change in FCGR2A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":542
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Determine whether PTPRS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Determine whether PTPRS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":666
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF2C is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4572
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and TLCD2 expression is observed. Does this perturbation lead to a significant difference in TLCD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and TLCD2 expression is observed. Does this perturbation lead to a significant difference in TLCD2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5553
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Determine whether COL18A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of COL18A1-AS1 is measured. Determine whether COL18A1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":636
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of COL21A1. Does perturbing IGDCC3 lead to a significant change in COL21A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of COL21A1. Does perturbing IGDCC3 lead to a significant change in COL21A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4421
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ADD3 expression. Decide whether this perturbation leads to a significant alteration in ADD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ADD3 expression. Decide whether this perturbation leads to a significant alteration in ADD3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2908
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of PCDHGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of PCDHGA3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2567
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of TXNIP. Does this perturbation cause a significant change in TXNIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4694
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FEV, does the expression profile of C10orf11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":677
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LGALS1. Does perturbing SNAI1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LGALS1. Does perturbing SNAI1 lead to a significant change in LGALS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5811
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CYP1B1-AS1. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HNF4A and then measure expression of CYP1B1-AS1. Does this perturbation cause a significant change in CYP1B1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4314
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of MYLIP. Does this perturbation cause a significant change in MYLIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of MYLIP. Does this perturbation cause a significant change in MYLIP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1234
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of RLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZC3HAV1, does the expression profile of RLN3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5007
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of CCNG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SGK1, does the expression profile of CCNG2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4067
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ANXA3 expression. Decide whether this perturbation leads to a significant alteration in ANXA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor ANXA3 expression. Decide whether this perturbation leads to a significant alteration in ANXA3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3968
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RP4-550H1.4. Does this perturbation cause a significant change in RP4-550H1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN9 and then measure expression of RP4-550H1.4. Does this perturbation cause a significant change in RP4-550H1.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5794
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Determine whether CTD-2031P19.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Determine whether CTD-2031P19.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":886
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LHX1 is perturbed and CST3 expression is observed. Does this perturbation lead to a significant difference in CST3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":973
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and LRRC36 expression is measured. Determine whether LRRC36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA1 is perturbed and LRRC36 expression is measured. Determine whether LRRC36 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":339
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and KIF2C expression is measured. Determine whether KIF2C exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4569
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Determine whether COL21A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IGDCC3 is perturbed and the expression of COL21A1 is measured. Determine whether COL21A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4426
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and RP1-59D14.10 expression is measured. Determine whether RP1-59D14.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and RP1-59D14.10 expression is measured. Determine whether RP1-59D14.10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3779
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of TMEM88. Does perturbing STIL lead to a significant change in TMEM88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb STIL and examine the expression of TMEM88. Does perturbing STIL lead to a significant change in TMEM88 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5181
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and AC145110.1 expression is quantified. Does this perturbation result in a significant change in AC145110.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and AC145110.1 expression is quantified. Does this perturbation result in a significant change in AC145110.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3112
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and C10orf11 expression is observed. Does this perturbation lead to a significant difference in C10orf11 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":673
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RGPD5 expression. Decide whether this perturbation leads to a significant alteration in RGPD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CITED1 and monitor RGPD5 expression. Decide whether this perturbation leads to a significant alteration in RGPD5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5968
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is measured. Determine whether RP4-565E6.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and RP4-565E6.1 expression is measured. Determine whether RP4-565E6.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":299
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Does this perturbation cause a significant change in ANXA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of ANXA3 is measured. Does this perturbation cause a significant change in ANXA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3960
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RNF168 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RNF168 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":777
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Does this perturbation cause a significant change in TYROBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":560
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ABCA13. Does perturbing POU3F2 lead to a significant change in ABCA13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of ABCA13. Does perturbing POU3F2 lead to a significant change in ABCA13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2091
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CCNB1 expression is quantified. Does this perturbation result in a significant change in CCNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, C3orf72 is perturbed and CCNB1 expression is quantified. Does this perturbation result in a significant change in CCNB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3852
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and MYB expression is observed. Does this perturbation lead to a significant difference in MYB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and MYB expression is observed. Does this perturbation lead to a significant difference in MYB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2103
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RGPD5. Does this perturbation cause a significant change in RGPD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CITED1 and then measure expression of RGPD5. Does this perturbation cause a significant change in RGPD5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5964
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Determine whether CAPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Determine whether CAPG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4876
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb EGR1 and monitor BLVRB expression. Decide whether this perturbation leads to a significant alteration in BLVRB expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6178
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of CRYAB. Does perturbing MAP4K5 lead to a significant change in CRYAB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K5 and examine the expression of CRYAB. Does perturbing MAP4K5 lead to a significant change in CRYAB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1341
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4820
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of FADS1. Does this perturbation cause a significant change in FADS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4104
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of TMEM88. Does this perturbation cause a significant change in TMEM88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of TMEM88. Does this perturbation cause a significant change in TMEM88 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5184
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of AVP. Does this perturbation cause a significant change in AVP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":64
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Determine whether RP11-1017G21.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARRDC3 is perturbed and the expression of RP11-1017G21.6 is measured. Determine whether RP11-1017G21.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3826
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Determine whether RP11-968A15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of RP11-968A15.2 is measured. Determine whether RP11-968A15.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":836
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPA is perturbed and the expression of AP1S2 is measured. Does this perturbation cause a significant change in AP1S2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4210
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of S100A13. Does perturbing FOXO4 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXO4 and examine the expression of S100A13. Does perturbing FOXO4 lead to a significant change in S100A13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1821
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in TNFAIP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CELF2 is associated with a significant change in TNFAIP8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2185
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of PERM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TGFBR2, does the expression profile of PERM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5487
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and MACF1 expression is observed. Does this perturbation lead to a significant difference in MACF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and MACF1 expression is observed. Does this perturbation lead to a significant difference in MACF1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4733
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of AKAP13. Does this perturbation cause a significant change in AKAP13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K6 and then measure expression of AKAP13. Does this perturbation cause a significant change in AKAP13 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3984
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RPL17-C18orf32. Does perturbing PTPN9 lead to a significant change in RPL17-C18orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of RPL17-C18orf32. Does perturbing PTPN9 lead to a significant change in RPL17-C18orf32 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5771
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and RAB5B expression is observed. Does this perturbation lead to a significant difference in RAB5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and RAB5B expression is observed. Does this perturbation lead to a significant difference in RAB5B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":683
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of UBE2H indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5517
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and DPYSL2 expression is quantified. Does this perturbation result in a significant change in DPYSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and DPYSL2 expression is quantified. Does this perturbation result in a significant change in DPYSL2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5802
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Determine whether DSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Determine whether DSC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1296
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in FNDC3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in FNDC3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4585
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Does this perturbation cause a significant change in CAPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of CAPG is measured. Does this perturbation cause a significant change in CAPG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4870
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ANXA3. Does perturbing MAP2K6 lead to a significant change in ANXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K6 and examine the expression of ANXA3. Does perturbing MAP2K6 lead to a significant change in ANXA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3961
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of CALY. Does perturbing DLX2 lead to a significant change in CALY expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of CALY. Does perturbing DLX2 lead to a significant change in CALY expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1591
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ISL2 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4448
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP1B1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HNF4A is perturbed and CYP1B1-AS1 expression is quantified. Does this perturbation result in a significant change in CYP1B1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4312
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FAM83A expression. Decide whether this perturbation leads to a significant alteration in FAM83A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FAM83A expression. Decide whether this perturbation leads to a significant alteration in FAM83A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5628
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of NKG7. Does perturbing UBASH3B lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3B and examine the expression of NKG7. Does perturbing UBASH3B lead to a significant change in NKG7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1381
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4479
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ICAM4 expression is quantified. Does this perturbation result in a significant change in ICAM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNNM4 is perturbed and ICAM4 expression is quantified. Does this perturbation result in a significant change in ICAM4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4742
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and GIPC2 expression is quantified. Does this perturbation result in a significant change in GIPC2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3152
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is quantified. Does this perturbation result in a significant change in RP11-714G18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and RP11-714G18.1 expression is quantified. Does this perturbation result in a significant change in RP11-714G18.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1852
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZNF318 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1148
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in TAS1R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in TAS1R1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":705
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-505P4.7 expression is measured. Determine whether RP11-505P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-505P4.7 expression is measured. Determine whether RP11-505P4.7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2559
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP7D1 is perturbed and CST3 expression is quantified. Does this perturbation result in a significant change in CST3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2742
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HCN1 expression. Decide whether this perturbation leads to a significant alteration in HCN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor HCN1 expression. Decide whether this perturbation leads to a significant alteration in HCN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3048
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HES7 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1720
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3B, does the expression profile of CTB-161C1.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1417
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is measured. Determine whether UCKL1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPB is perturbed and UCKL1-AS1 expression is measured. Determine whether UCKL1-AS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5259
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Does this perturbation cause a significant change in TEX30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN1 is perturbed and the expression of TEX30 is measured. Does this perturbation cause a significant change in TEX30 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2410
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Does this perturbation cause a significant change in ITGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Does this perturbation cause a significant change in ITGA3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4130
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in DLX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in DLX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6165
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ADD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of C19orf26 is associated with a significant change in ADD3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2905
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of COL18A1-AS1. Does this perturbation cause a significant change in COL18A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of COL18A1-AS1. Does this perturbation cause a significant change in COL18A1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":634
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor RP11-1085N6.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-1085N6.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor RP11-1085N6.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-1085N6.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3408
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is measured. Determine whether RP11-290L1.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and RP11-290L1.2 expression is measured. Determine whether RP11-290L1.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2039
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of LPAR2. Does this perturbation cause a significant change in LPAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of LPAR2. Does this perturbation cause a significant change in LPAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3104
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KMT2A is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4329
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of DST. Does this perturbation cause a significant change in DST expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2344
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of RASGRF2. Does perturbing MIDN lead to a significant change in RASGRF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MIDN and examine the expression of RASGRF2. Does perturbing MIDN lead to a significant change in RASGRF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1541
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and HBG1 expression is quantified. Does this perturbation result in a significant change in HBG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and HBG1 expression is quantified. Does this perturbation result in a significant change in HBG1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5382
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in SLCO6A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KMT2A is associated with a significant change in SLCO6A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4355
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Does this perturbation cause a significant change in CLU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TSC22D1 is perturbed and the expression of CLU is measured. Does this perturbation cause a significant change in CLU expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":10
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in AC007193.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in AC007193.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2635
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and LRRC36 expression is quantified. Does this perturbation result in a significant change in LRRC36 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA1 is perturbed and LRRC36 expression is quantified. Does this perturbation result in a significant change in LRRC36 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":332
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ATF6B expression is observed. Does this perturbation lead to a significant difference in ATF6B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which NIT1 is perturbed and ATF6B expression is observed. Does this perturbation lead to a significant difference in ATF6B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5323
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is measured. Determine whether RP11-286H15.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and RP11-286H15.1 expression is measured. Determine whether RP11-286H15.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2519
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ATP8B4 expression is quantified. Does this perturbation result in a significant change in ATP8B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and ATP8B4 expression is quantified. Does this perturbation result in a significant change in ATP8B4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1552
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Does this perturbation cause a significant change in VGF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ELMSAN1 is perturbed and the expression of VGF is measured. Does this perturbation cause a significant change in VGF expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":260
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor CEBPD expression. Decide whether this perturbation leads to a significant alteration in CEBPD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor CEBPD expression. Decide whether this perturbation leads to a significant alteration in CEBPD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6068
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and TRGVA expression is observed. Does this perturbation lead to a significant difference in TRGVA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX3 is perturbed and TRGVA expression is observed. Does this perturbation lead to a significant difference in TRGVA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":953
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is measured. Determine whether SIGLEC15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RUNX1T1 is perturbed and SIGLEC15 expression is measured. Determine whether SIGLEC15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1969
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Determine whether HIST1H4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of HIST1H4H is measured. Determine whether HIST1H4H shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4346
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of CD52 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":87
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of RP11-1085N6.3. Does perturbing SAMD1 lead to a significant change in RP11-1085N6.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of RP11-1085N6.3. Does perturbing SAMD1 lead to a significant change in RP11-1085N6.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3401
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and APOL6 expression is measured. Determine whether APOL6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and APOL6 expression is measured. Determine whether APOL6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3429
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RP5-1142A6.2 expression. Decide whether this perturbation leads to a significant alteration in RP5-1142A6.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor RP5-1142A6.2 expression. Decide whether this perturbation leads to a significant alteration in RP5-1142A6.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4718
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor CFH expression. Decide whether this perturbation leads to a significant alteration in CFH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5448
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ANXA2R. Does perturbing HOXA13 lead to a significant change in ANXA2R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of ANXA2R. Does perturbing HOXA13 lead to a significant change in ANXA2R expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5871
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and FABP5 expression is measured. Determine whether FABP5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3069
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of ACE is measured. Determine whether ACE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3656
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SNCG expression is observed. Does this perturbation lead to a significant difference in SNCG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and SNCG expression is observed. Does this perturbation lead to a significant difference in SNCG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1983
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in FEV expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2465
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor PXK expression. Decide whether this perturbation leads to a significant alteration in PXK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CELF2 and monitor PXK expression. Decide whether this perturbation leads to a significant alteration in PXK expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2178
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor RP11-662J14.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-662J14.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor RP11-662J14.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-662J14.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5248
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RHOH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RHOH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4457
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AMHR2 is measured. Does this perturbation cause a significant change in AMHR2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5700
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ATL1 is perturbed and the expression of LST1 is measured. Determine whether LST1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5266
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":426
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CTD-3126B10.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3126B10.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CTD-3126B10.4 expression is observed. Does this perturbation lead to a significant difference in CTD-3126B10.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2393
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of CTC-490E21.10. Does perturbing KLF1 lead to a significant change in CTC-490E21.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of CTC-490E21.10. Does perturbing KLF1 lead to a significant change in CTC-490E21.10 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":571
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor SLC38A2 expression. Decide whether this perturbation leads to a significant alteration in SLC38A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC38A2 and monitor SLC38A2 expression. Decide whether this perturbation leads to a significant alteration in SLC38A2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5698
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, OSR2 is perturbed and RNF213 expression is measured. Determine whether RNF213 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5029
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Determine whether DDX58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of DDX58 is measured. Determine whether DDX58 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":226
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-505P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IER5L is associated with a significant change in RP11-505P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2555
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-128B16.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-128B16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor RP11-128B16.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-128B16.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1798
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and CISH expression is quantified. Does this perturbation result in a significant change in CISH expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3602
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in RP11-452C8.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SGK1 is associated with a significant change in RP11-452C8.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4075
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF18B, does the expression profile of RP1-34B20.21 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6117
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and CAPG expression is quantified. Does this perturbation result in a significant change in CAPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and CAPG expression is quantified. Does this perturbation result in a significant change in CAPG expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4872
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Determine whether ZIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of ZIC4 is measured. Determine whether ZIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2616
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Determine whether ACSL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Determine whether ACSL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2776
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ID3 expression is quantified. Does this perturbation result in a significant change in ID3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3482
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ZNF677. Does this perturbation cause a significant change in ZNF677 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of ZNF677. Does this perturbation cause a significant change in ZNF677 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3094
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DUSP9, does the expression profile of TSC22D4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":197
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SNCG. Does this perturbation cause a significant change in SNCG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of SNCG. Does this perturbation cause a significant change in SNCG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1984
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Determine whether CRAT37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Determine whether CRAT37 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6196
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Does this perturbation cause a significant change in RUNX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4680
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K3 is associated with a significant change in IGDCC3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2325
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor LPAR2 expression. Decide whether this perturbation leads to a significant alteration in LPAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXB9 and monitor LPAR2 expression. Decide whether this perturbation leads to a significant alteration in LPAR2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3108
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KMT2A is perturbed and the expression of TM6SF2 is measured. Determine whether TM6SF2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4376
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Determine whether MS4A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Determine whether MS4A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3936
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of EGR1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6177
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor FZD6 expression. Decide whether this perturbation leads to a significant alteration in FZD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor FZD6 expression. Decide whether this perturbation leads to a significant alteration in FZD6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2998
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of AC007193.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN12, does the expression profile of AC007193.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2637
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of TUBB2B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1587
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Determine whether NCALD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of NCALD is measured. Determine whether NCALD shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4836
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Does this perturbation cause a significant change in UBASH3A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4800
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor CTB-49A3.5 expression. Decide whether this perturbation leads to a significant alteration in CTB-49A3.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SAMD1 and monitor CTB-49A3.5 expression. Decide whether this perturbation leads to a significant alteration in CTB-49A3.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3398
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and IGDCC3 expression is measured. Determine whether IGDCC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2329
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNX1. Does perturbing FOSB lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOSB and examine the expression of RUNX1. Does perturbing FOSB lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2781
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3453
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and TRPM2 expression is measured. Determine whether TRPM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and TRPM2 expression is measured. Determine whether TRPM2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1429
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXB9 is perturbed and SAT2 expression is quantified. Does this perturbation result in a significant change in SAT2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3072
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SET and then measure expression of NCF4. Does this perturbation cause a significant change in NCF4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":854
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of ALAS2. Does this perturbation cause a significant change in ALAS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2304
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and MYLIP expression is observed. Does this perturbation lead to a significant difference in MYLIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and MYLIP expression is observed. Does this perturbation lead to a significant difference in MYLIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1233
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in AP1S2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4265
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in XX-FW83563B9.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in XX-FW83563B9.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3295
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LRP10 expression is measured. Determine whether LRP10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and LRP10 expression is measured. Determine whether LRP10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3319
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and AC007556.3 expression is quantified. Does this perturbation result in a significant change in AC007556.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and AC007556.3 expression is quantified. Does this perturbation result in a significant change in AC007556.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":822
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PLK4 is perturbed and PNMT expression is observed. Does this perturbation lead to a significant difference in PNMT expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3663
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and SLC4A3 expression is observed. Does this perturbation lead to a significant difference in SLC4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and SLC4A3 expression is observed. Does this perturbation lead to a significant difference in SLC4A3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6083
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and MCC expression is observed. Does this perturbation lead to a significant difference in MCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and MCC expression is observed. Does this perturbation lead to a significant difference in MCC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3513
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Determine whether IFIT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of IFIT2 is measured. Determine whether IFIT2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6026
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in SOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX2 is associated with a significant change in SOX5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2475
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of TLCD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of JUN, does the expression profile of TLCD2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5557
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TM6SF2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4377
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and MT1E expression is quantified. Does this perturbation result in a significant change in MT1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and MT1E expression is quantified. Does this perturbation result in a significant change in MT1E expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":362
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and LINC00479 expression is observed. Does this perturbation lead to a significant difference in LINC00479 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and LINC00479 expression is observed. Does this perturbation lead to a significant difference in LINC00479 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":413
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and IL1RN expression is observed. Does this perturbation lead to a significant difference in IL1RN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CELF2 is perturbed and IL1RN expression is observed. Does this perturbation lead to a significant difference in IL1RN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2193
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of FAM178B indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1747
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and FNDC3A expression is measured. Determine whether FNDC3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF2C is perturbed and FNDC3A expression is measured. Determine whether FNDC3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4589
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of AGXT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of AGXT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1057
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Determine whether RP11-109E24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Determine whether RP11-109E24.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6216
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of BST2. Does this perturbation cause a significant change in BST2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5454
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of FOXL2 is measured. Determine whether FOXL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3686
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ATL1, does the expression profile of ESAM indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5277
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RUNX1. Does perturbing ARID1A lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ARID1A and examine the expression of RUNX1. Does perturbing ARID1A lead to a significant change in RUNX1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4681
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb AHR and monitor FAM178B expression. Decide whether this perturbation leads to a significant alteration in FAM178B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1748
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of TPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of TPH2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3417
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and TRAPPC3L expression is observed. Does this perturbation lead to a significant difference in TRAPPC3L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and TRAPPC3L expression is observed. Does this perturbation lead to a significant difference in TRAPPC3L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6253
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and AC006262.5 expression is observed. Does this perturbation lead to a significant difference in AC006262.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":493
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of RSPO4. Does perturbing FOXL2 lead to a significant change in RSPO4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of RSPO4. Does perturbing FOXL2 lead to a significant change in RSPO4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4111
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CDC45 expression. Decide whether this perturbation leads to a significant alteration in CDC45 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":128
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ADGRF1 expression is quantified. Does this perturbation result in a significant change in ADGRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC38A2 is perturbed and ADGRF1 expression is quantified. Does this perturbation result in a significant change in ADGRF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5722
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is quantified. Does this perturbation result in a significant change in TFAP2A-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and TFAP2A-AS1 expression is quantified. Does this perturbation result in a significant change in TFAP2A-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4362
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PTRF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PTRF expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1035
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Does this perturbation cause a significant change in CRAT37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CRAT37 is measured. Does this perturbation cause a significant change in CRAT37 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6190
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Does this perturbation cause a significant change in RP11-328J14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of RP11-328J14.1 is measured. Does this perturbation cause a significant change in RP11-328J14.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2570
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and RP1-34B20.21 expression is measured. Determine whether RP1-34B20.21 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6119
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of TLN1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1527
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of WBP2. Does this perturbation cause a significant change in WBP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5164
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Does this perturbation cause a significant change in HCN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of HCN1 is measured. Does this perturbation cause a significant change in HCN1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3040
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is measured. Determine whether RP11-76E17.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and RP11-76E17.2 expression is measured. Determine whether RP11-76E17.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3349
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CNN1, does the expression profile of BLVRB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2127
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of IER5L, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2547
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and LINC01342 expression is quantified. Does this perturbation result in a significant change in LINC01342 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CELF2 is perturbed and LINC01342 expression is quantified. Does this perturbation result in a significant change in LINC01342 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2202
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of RP11-195C7.1. Does perturbing HES7 lead to a significant change in RP11-195C7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HES7 and examine the expression of RP11-195C7.1. Does perturbing HES7 lead to a significant change in RP11-195C7.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1731
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K3 is perturbed and TFAP2A expression is observed. Does this perturbation lead to a significant difference in TFAP2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2313
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CD59 expression is observed. Does this perturbation lead to a significant difference in CD59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and CD59 expression is observed. Does this perturbation lead to a significant difference in CD59 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2373
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of PTPRS. Does perturbing FEV lead to a significant change in PTPRS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of PTPRS. Does perturbing FEV lead to a significant change in PTPRS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":661
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and TNFRSF12A expression is observed. Does this perturbation lead to a significant difference in TNFRSF12A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which LYL1 is perturbed and TNFRSF12A expression is observed. Does this perturbation lead to a significant difference in TNFRSF12A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3903
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and FMNL1 expression is measured. Determine whether FMNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and FMNL1 expression is measured. Determine whether FMNL1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1699
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of RUNX1 is measured. Determine whether RUNX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4686
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and EWSAT1 expression is observed. Does this perturbation lead to a significant difference in EWSAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ATL1 is perturbed and EWSAT1 expression is observed. Does this perturbation lead to a significant difference in EWSAT1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5313
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in LINC01003 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MEIS1 is associated with a significant change in LINC01003 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":455
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of FCGR3A. Does perturbing ZBTB10 lead to a significant change in FCGR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB10 and examine the expression of FCGR3A. Does perturbing ZBTB10 lead to a significant change in FCGR3A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5601
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ZNF85. Does this perturbation cause a significant change in ZNF85 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to GLB1L2 and then measure expression of ZNF85. Does this perturbation cause a significant change in ZNF85 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":514
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor AC016629.3 expression. Decide whether this perturbation leads to a significant alteration in AC016629.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":328
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBFA2T3 and monitor WBP2 expression. Decide whether this perturbation leads to a significant alteration in WBP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1658
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, JUN is perturbed and UBE2H expression is quantified. Does this perturbation result in a significant change in UBE2H expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5512
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of TRGVA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of TRGVA indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":957
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and HBE1 expression is measured. Determine whether HBE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and HBE1 expression is measured. Determine whether HBE1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":449
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Determine whether SERPINF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RREB1 is perturbed and the expression of SERPINF1 is measured. Determine whether SERPINF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1086
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXL2, does the expression profile of FADS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4107
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of TOX. Does this perturbation cause a significant change in TOX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of TOX. Does this perturbation cause a significant change in TOX expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1364
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RP3-467K16.2. Does perturbing SLC6A9 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC6A9 and examine the expression of RP3-467K16.2. Does perturbing SLC6A9 lead to a significant change in RP3-467K16.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1471
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in RP4-565E6.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in RP4-565E6.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":295
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and FCGR3A expression is measured. Determine whether FCGR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and FCGR3A expression is measured. Determine whether FCGR3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5609
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CCS expression is quantified. Does this perturbation result in a significant change in CCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and CCS expression is quantified. Does this perturbation result in a significant change in CCS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":132
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Does this perturbation cause a significant change in DLX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of DLX4 is measured. Does this perturbation cause a significant change in DLX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6160
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Does this perturbation cause a significant change in AC004051.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXO4 is perturbed and the expression of AC004051.2 is measured. Does this perturbation cause a significant change in AC004051.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1840
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of TNNI3 is measured. Does this perturbation cause a significant change in TNNI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2700
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3A is perturbed and UBASH3A expression is quantified. Does this perturbation result in a significant change in UBASH3A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4802
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of MYC. Does this perturbation cause a significant change in MYC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IKZF3 and then measure expression of MYC. Does this perturbation cause a significant change in MYC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3024
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which EGR1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6173
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SLC2A3 expression is quantified. Does this perturbation result in a significant change in SLC2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IER5L is perturbed and SLC2A3 expression is quantified. Does this perturbation result in a significant change in SLC2A3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2532
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-567N4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of AHR, does the expression profile of RP11-567N4.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1787
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZC3HAV1 is perturbed and ZC3HAV1 expression is measured. Determine whether ZC3HAV1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4979
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and TUBB3 expression is observed. Does this perturbation lead to a significant difference in TUBB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and TUBB3 expression is observed. Does this perturbation lead to a significant difference in TUBB3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3593
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of MMP19. Does perturbing TBX3 lead to a significant change in MMP19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX3 and examine the expression of MMP19. Does perturbing TBX3 lead to a significant change in MMP19 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":941
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of H1FNT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of H1FNT indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2917
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and AIF1 expression is quantified. Does this perturbation result in a significant change in AIF1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2282
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of C10orf11. Does this perturbation cause a significant change in C10orf11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":674
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of CTNNB1. Does perturbing GLB1L2 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb GLB1L2 and examine the expression of CTNNB1. Does perturbing GLB1L2 lead to a significant change in CTNNB1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":501
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is quantified. Does this perturbation result in a significant change in RP11-180M15.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and RP11-180M15.6 expression is quantified. Does this perturbation result in a significant change in RP11-180M15.6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4432
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CPXM1 expression is quantified. Does this perturbation result in a significant change in CPXM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BCORL1 is perturbed and CPXM1 expression is quantified. Does this perturbation result in a significant change in CPXM1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":382
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CTD-2012K14.6 expression. Decide whether this perturbation leads to a significant alteration in CTD-2012K14.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CTD-2012K14.6 expression. Decide whether this perturbation leads to a significant alteration in CTD-2012K14.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5218
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Determine whether C1orf141 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP4K3 is perturbed and the expression of C1orf141 is measured. Determine whether C1orf141 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2336
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CBL and monitor NCF4 expression. Decide whether this perturbation leads to a significant alteration in NCF4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":728
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and RETN expression is measured. Determine whether RETN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and RETN expression is measured. Determine whether RETN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2459
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Does this perturbation cause a significant change in ARPC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of ARPC3 is measured. Does this perturbation cause a significant change in ARPC3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":840
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of RABGAP1L is measured. Determine whether RABGAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3556
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TUBA1A. Does perturbing MAP7D1 lead to a significant change in TUBA1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TUBA1A. Does perturbing MAP7D1 lead to a significant change in TUBA1A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2711
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NCL is perturbed and the expression of NBR1 is measured. Does this perturbation cause a significant change in NBR1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4880
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in PRSS57 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4165
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Does this perturbation cause a significant change in AK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of AK8 is measured. Does this perturbation cause a significant change in AK8 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4390
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Does this perturbation cause a significant change in SLC38A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of SLC38A2 is measured. Does this perturbation cause a significant change in SLC38A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5690
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of FCGR2A. Does perturbing KLF1 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of FCGR2A. Does perturbing KLF1 lead to a significant change in FCGR2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":541
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ZMAT3. Does perturbing SPI1 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of ZMAT3. Does perturbing SPI1 lead to a significant change in ZMAT3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5131
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and DPYSL2 expression is observed. Does this perturbation lead to a significant difference in DPYSL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and DPYSL2 expression is observed. Does this perturbation lead to a significant difference in DPYSL2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5803
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":123
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of RP11-1085N6.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of RP11-1085N6.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3407
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-328J14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor RP11-328J14.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-328J14.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2578
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Determine whether ASIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Determine whether ASIC4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2246
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CKS1B is perturbed and the expression of THBS1 is measured. Does this perturbation cause a significant change in THBS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3210
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Determine whether TUBB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of TUBB3 is measured. Determine whether TUBB3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3596
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of PSMB8. Does perturbing MAML2 lead to a significant change in PSMB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAML2 and examine the expression of PSMB8. Does perturbing MAML2 lead to a significant change in PSMB8 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":101
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in SLC22A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HNF4A is associated with a significant change in SLC22A11 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4305
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of ZNF467 is measured. Does this perturbation cause a significant change in ZNF467 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6130
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of STRC. Does this perturbation cause a significant change in STRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of STRC. Does this perturbation cause a significant change in STRC expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5904
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCM2L expression is measured. Determine whether CCM2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNN1 is perturbed and CCM2L expression is measured. Determine whether CCM2L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2149
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP11-445O3.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TSC22D1, does the expression profile of RP11-445O3.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":47
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IKZF3 is perturbed and AVP expression is measured. Determine whether AVP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3009
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCORL1 and then measure expression of SH3BGRL. Does this perturbation cause a significant change in SH3BGRL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":394
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of TLCD2. Does perturbing JUN lead to a significant change in TLCD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of TLCD2. Does perturbing JUN lead to a significant change in TLCD2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5551
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ISL2 is perturbed and the expression of RNF213 is measured. Does this perturbation cause a significant change in RNF213 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4470
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAML2 is perturbed and the expression of AVP is measured. Does this perturbation cause a significant change in AVP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":60
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor RLN3 expression. Decide whether this perturbation leads to a significant alteration in RLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor RLN3 expression. Decide whether this perturbation leads to a significant alteration in RLN3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5008
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5680
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Does this perturbation cause a significant change in LRP10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA3 is perturbed and the expression of LRP10 is measured. Does this perturbation cause a significant change in LRP10 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3310
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of RP11-505P4.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RREB1, does the expression profile of RP11-505P4.6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1137
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and FCGR2A expression is observed. Does this perturbation lead to a significant difference in FCGR2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":543
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ZNF610 expression is quantified. Does this perturbation result in a significant change in ZNF610 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and ZNF610 expression is quantified. Does this perturbation result in a significant change in ZNF610 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2432
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Determine whether PKIG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Determine whether PKIG shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":206
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of PYROXD2 is measured. Determine whether PYROXD2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2226
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of PCDHGA3. Does perturbing IER5L lead to a significant change in PCDHGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of PCDHGA3. Does perturbing IER5L lead to a significant change in PCDHGA3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2561
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF18B and monitor RP1-34B20.21 expression. Decide whether this perturbation leads to a significant alteration in RP1-34B20.21 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6118
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ZIC4 expression. Decide whether this perturbation leads to a significant alteration in ZIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN12 and monitor ZIC4 expression. Decide whether this perturbation leads to a significant alteration in ZIC4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2618
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of C19orf38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of C19orf38 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4847
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of COL1A1 is measured. Determine whether COL1A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5056
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Does this perturbation cause a significant change in CCDC148 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNN1 is perturbed and the expression of CCDC148 is measured. Does this perturbation cause a significant change in CCDC148 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2130
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Determine whether TPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TMSB4X is perturbed and the expression of TPM4 is measured. Determine whether TPM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4516
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3A is perturbed and the expression of UBASH3A is measured. Determine whether UBASH3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4826
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and CCNJL expression is measured. Determine whether CCNJL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SPI1 is perturbed and CCNJL expression is measured. Determine whether CCNJL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5129
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C6orf1. Does perturbing RHOXF2BB lead to a significant change in C6orf1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of C6orf1. Does perturbing RHOXF2BB lead to a significant change in C6orf1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1871
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of PIM2. Does this perturbation cause a significant change in PIM2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2954
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PLK4 and then measure expression of PNMT. Does this perturbation cause a significant change in PNMT expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3664
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLA2G1B expression is quantified. Does this perturbation result in a significant change in PLA2G1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLA2G1B expression is quantified. Does this perturbation result in a significant change in PLA2G1B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":752
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ATP8A1 expression is quantified. Does this perturbation result in a significant change in ATP8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and ATP8A1 expression is quantified. Does this perturbation result in a significant change in ATP8A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3522
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of PRSS57. Does this perturbation cause a significant change in PRSS57 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1154
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is quantified. Does this perturbation result in a significant change in RP11-320G24.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RP11-320G24.1 expression is quantified. Does this perturbation result in a significant change in RP11-320G24.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5062
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ARID1A is perturbed and TXNIP expression is observed. Does this perturbation lead to a significant difference in TXNIP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4693
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CTD-3126B10.4. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CTD-3126B10.4. Does this perturbation cause a significant change in CTD-3126B10.4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2394
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, EGR1 is perturbed and BLVRB expression is quantified. Does this perturbation result in a significant change in BLVRB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6172
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor KRT79 expression. Decide whether this perturbation leads to a significant alteration in KRT79 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C3orf72 and monitor KRT79 expression. Decide whether this perturbation leads to a significant alteration in KRT79 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3888
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LRRTM4. Does perturbing SNAI1 lead to a significant change in LRRTM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of LRRTM4. Does perturbing SNAI1 lead to a significant change in LRRTM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5841
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of APOL6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of COL1A1, does the expression profile of APOL6 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3427
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CKS1B is perturbed and ZC3HAV1 expression is observed. Does this perturbation lead to a significant difference in ZC3HAV1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3193
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of RP11-286H15.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of RP11-286H15.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2517
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BPGM is perturbed and CD24 expression is quantified. Does this perturbation result in a significant change in CD24 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3732
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SPANXN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SPANXN5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3465
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of LINC01338 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of LINC01338 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5077
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of TFRC. Does perturbing COL2A1 lead to a significant change in TFRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of TFRC. Does perturbing COL2A1 lead to a significant change in TFRC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1221
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C6orf1 expression is quantified. Does this perturbation result in a significant change in C6orf1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and C6orf1 expression is quantified. Does this perturbation result in a significant change in C6orf1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1872
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of EMP3. Does perturbing IKZF3 lead to a significant change in EMP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IKZF3 and examine the expression of EMP3. Does perturbing IKZF3 lead to a significant change in EMP3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3031
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ISL2 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4444
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP11-345P4.7. Does this perturbation cause a significant change in RP11-345P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAPK1 and then measure expression of RP11-345P4.7. Does this perturbation cause a significant change in RP11-345P4.7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2874
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TRIM22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4597
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2989
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-567N4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-567N4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-567N4.3 expression is observed. Does this perturbation lead to a significant difference in RP11-567N4.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1783
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and SEMA3B expression is observed. Does this perturbation lead to a significant difference in SEMA3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and SEMA3B expression is observed. Does this perturbation lead to a significant difference in SEMA3B expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4243
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Does this perturbation cause a significant change in HMOX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CITED1 is perturbed and the expression of HMOX1 is measured. Does this perturbation cause a significant change in HMOX1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5970
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PLK4 is perturbed and PNMT expression is quantified. Does this perturbation result in a significant change in PNMT expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3662
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1B is perturbed and CDC20 expression is measured. Determine whether CDC20 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5409
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PAMR1 expression. Decide whether this perturbation leads to a significant alteration in PAMR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CNNM4 and monitor PAMR1 expression. Decide whether this perturbation leads to a significant alteration in PAMR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4798
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which UBASH3A is perturbed and AC074289.1 expression is observed. Does this perturbation lead to a significant difference in AC074289.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4853
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Does this perturbation cause a significant change in LRRC36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of LRRC36 is measured. Does this perturbation cause a significant change in LRRC36 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":330
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HK2, does the expression profile of MFSD2A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6097
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CYP3A5 expression is observed. Does this perturbation lead to a significant difference in CYP3A5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SET is perturbed and CYP3A5 expression is observed. Does this perturbation lead to a significant difference in CYP3A5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":863
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Does this perturbation cause a significant change in S100A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of S100A3 is measured. Does this perturbation cause a significant change in S100A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1910
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and MFSD2A expression is observed. Does this perturbation lead to a significant difference in MFSD2A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3873
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and NKG7 expression is observed. Does this perturbation lead to a significant difference in NKG7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4463
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Determine whether RP11-514P8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Determine whether RP11-514P8.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3696
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of MAP7D1. Does this perturbation cause a significant change in MAP7D1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2724
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX3 and monitor CHI3L2 expression. Decide whether this perturbation leads to a significant alteration in CHI3L2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":908
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and FADS1 expression is observed. Does this perturbation lead to a significant difference in FADS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1453
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of HCAR2. Does this perturbation cause a significant change in HCAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to STIL and then measure expression of HCAR2. Does this perturbation cause a significant change in HCAR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5194
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Does this perturbation cause a significant change in SLC22A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Does this perturbation cause a significant change in SLC22A11 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4300
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of KRT79. Does perturbing C3orf72 lead to a significant change in KRT79 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C3orf72 and examine the expression of KRT79. Does perturbing C3orf72 lead to a significant change in KRT79 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3881
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Determine whether PLA2G1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CBL is perturbed and the expression of PLA2G1B is measured. Determine whether PLA2G1B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":756
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MEIS1 is perturbed and TUBB2B expression is measured. Determine whether TUBB2B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":439
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and LEFTY1 expression is observed. Does this perturbation lead to a significant difference in LEFTY1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and LEFTY1 expression is observed. Does this perturbation lead to a significant difference in LEFTY1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5913
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RIT1 expression. Decide whether this perturbation leads to a significant alteration in RIT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor RIT1 expression. Decide whether this perturbation leads to a significant alteration in RIT1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4918
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and PLEK expression is observed. Does this perturbation lead to a significant difference in PLEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and PLEK expression is observed. Does this perturbation lead to a significant difference in PLEK expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5093
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Determine whether DRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN13 is perturbed and the expression of DRC1 is measured. Determine whether DRC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5666
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of HERPUD1. Does this perturbation cause a significant change in HERPUD1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5824
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in GPR157 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in GPR157 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3055
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and DDX58 expression is measured. Determine whether DDX58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and DDX58 expression is measured. Determine whether DDX58 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":229
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TSC22D1 and monitor RNF213 expression. Decide whether this perturbation leads to a significant alteration in RNF213 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":28
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of C10orf11. Does perturbing COL1A1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL1A1 and examine the expression of C10orf11. Does perturbing COL1A1 lead to a significant change in C10orf11 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3431
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and APOBR expression is observed. Does this perturbation lead to a significant difference in APOBR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and APOBR expression is observed. Does this perturbation lead to a significant difference in APOBR expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5173
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2950
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and LST1 expression is measured. Determine whether LST1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2949
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of FABP5. Does perturbing HOXB9 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXB9 and examine the expression of FABP5. Does perturbing HOXB9 lead to a significant change in FABP5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3061
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Determine whether RP11-128B16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-128B16.3 is measured. Determine whether RP11-128B16.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1796
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of PCK1. Does this perturbation cause a significant change in PCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC38A2 and then measure expression of PCK1. Does this perturbation cause a significant change in PCK1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5734
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of DDX58. Does perturbing DUSP9 lead to a significant change in DDX58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DUSP9 and examine the expression of DDX58. Does perturbing DUSP9 lead to a significant change in DDX58 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":221
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5047
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01420 expression is quantified. Does this perturbation result in a significant change in LINC01420 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and LINC01420 expression is quantified. Does this perturbation result in a significant change in LINC01420 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5422
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and HOXB6 expression is observed. Does this perturbation lead to a significant difference in HOXB6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ETS2 is perturbed and HOXB6 expression is observed. Does this perturbation lead to a significant difference in HOXB6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":813
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3710
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and HEMGN expression is observed. Does this perturbation lead to a significant difference in HEMGN expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1923
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in SAT1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1805
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SET is perturbed and the expression of NCF4 is measured. Determine whether NCF4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":856
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor AIF1 expression. Decide whether this perturbation leads to a significant alteration in AIF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2288
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Determine whether FAM46C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of FAM46C is measured. Determine whether FAM46C shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2896
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor GCM2 expression. Decide whether this perturbation leads to a significant alteration in GCM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K5 and monitor GCM2 expression. Decide whether this perturbation leads to a significant alteration in GCM2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1358
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is measured. Determine whether RHOXF2BB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC38A2 is perturbed and RHOXF2BB expression is measured. Determine whether RHOXF2BB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5719
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CBL is perturbed and the expression of NCF4 is measured. Does this perturbation cause a significant change in NCF4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":720
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Does this perturbation cause a significant change in RP11-635N19.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of RP11-635N19.1 is measured. Does this perturbation cause a significant change in RP11-635N19.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1370
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CTD-2012K14.6. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of CTD-2012K14.6. Does this perturbation cause a significant change in CTD-2012K14.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5214
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ISL2 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4466
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and EGOT expression is measured. Determine whether EGOT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and EGOT expression is measured. Determine whether EGOT exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5679
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Determine whether CENPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CDKN1C is perturbed and the expression of CENPE is measured. Determine whether CENPE shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6226
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of HSD17B4. Does perturbing CEBPE lead to a significant change in HSD17B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPE and examine the expression of HSD17B4. Does perturbing CEBPE lead to a significant change in HSD17B4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":141
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and RNF213 expression is quantified. Does this perturbation result in a significant change in RNF213 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5022
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in COL21A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IGDCC3 is associated with a significant change in COL21A1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4425
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LRP10. Does this perturbation cause a significant change in LRP10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of LRP10. Does this perturbation cause a significant change in LRP10 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3314
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Determine whether TOR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of TOR3A is measured. Determine whether TOR3A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5346
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of DCAF13. Does perturbing ZBTB1 lead to a significant change in DCAF13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of DCAF13. Does perturbing ZBTB1 lead to a significant change in DCAF13 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3541
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of SPANXD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of SPANXD indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4197
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and MYC expression is observed. Does this perturbation lead to a significant difference in MYC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and MYC expression is observed. Does this perturbation lead to a significant difference in MYC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3023
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of NBR1. Does perturbing HNF4A lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of NBR1. Does perturbing HNF4A lead to a significant change in NBR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4271
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Does this perturbation cause a significant change in PKIG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of PKIG is measured. Does this perturbation cause a significant change in PKIG expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":200
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in THBS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3215
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and TACC1 expression is observed. Does this perturbation lead to a significant difference in TACC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and TACC1 expression is observed. Does this perturbation lead to a significant difference in TACC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6003
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ORAI3. Does this perturbation cause a significant change in ORAI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RUNX1T1 and then measure expression of ORAI3. Does this perturbation cause a significant change in ORAI3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1944
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, LHX1 is perturbed and RP1-102K2.6 expression is measured. Determine whether RP1-102K2.6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1019
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of CCNJL. Does perturbing SPI1 lead to a significant change in CCNJL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SPI1 and examine the expression of CCNJL. Does perturbing SPI1 lead to a significant change in CCNJL expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5121
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ABCA13 expression. Decide whether this perturbation leads to a significant alteration in ABCA13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb POU3F2 and monitor ABCA13 expression. Decide whether this perturbation leads to a significant alteration in ABCA13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2098
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PAMR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in PAMR1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4795
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of MKNK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of MKNK2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1627
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RREB1 is perturbed and the expression of CTSL is measured. Does this perturbation cause a significant change in CTSL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1090
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in GRAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA1 is associated with a significant change in GRAP2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":315
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and TCAF2 expression is observed. Does this perturbation lead to a significant difference in TCAF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IRF1 is perturbed and TCAF2 expression is observed. Does this perturbation lead to a significant difference in TCAF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2973
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ISL2 is perturbed and FCER1G expression is observed. Does this perturbation lead to a significant difference in FCER1G expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4443
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BPGM is perturbed and the expression of CD9 is measured. Determine whether CD9 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3746
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TMSB4X is perturbed and TM6SF2 expression is observed. Does this perturbation lead to a significant difference in TM6SF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4543
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1C is perturbed and CDC45 expression is observed. Does this perturbation lead to a significant difference in CDC45 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6243
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in TOX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in TOX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1365
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and PGA4 expression is quantified. Does this perturbation result in a significant change in PGA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRDM1 is perturbed and PGA4 expression is quantified. Does this perturbation result in a significant change in PGA4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6032
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5985
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CITED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of CITED2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4287
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01358 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of LINC01358 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5617
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Determine whether MTURN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of MTURN is measured. Determine whether MTURN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1886
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, UBASH3B is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1382
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2600
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of GYPE. Does perturbing PRTG lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of GYPE. Does perturbing PRTG lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3621
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AC034228.4 expression is measured. Determine whether AC034228.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HNF4A is perturbed and AC034228.4 expression is measured. Determine whether AC034228.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4299
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of TFAP2A. Does perturbing MAP4K3 lead to a significant change in TFAP2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of TFAP2A. Does perturbing MAP4K3 lead to a significant change in TFAP2A expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2311
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of RP11-442O1.4. Does perturbing CSRNP1 lead to a significant change in RP11-442O1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of RP11-442O1.4. Does perturbing CSRNP1 lead to a significant change in RP11-442O1.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4661
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and C10orf11 expression is measured. Determine whether C10orf11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":679
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor SPARC expression. Decide whether this perturbation leads to a significant alteration in SPARC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor SPARC expression. Decide whether this perturbation leads to a significant alteration in SPARC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5528
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Determine whether STRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of STRC is measured. Determine whether STRC shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5906
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and DRC1 expression is measured. Determine whether DRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN13 is perturbed and DRC1 expression is measured. Determine whether DRC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5669
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-567N4.3 expression is measured. Determine whether RP11-567N4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-567N4.3 expression is measured. Determine whether RP11-567N4.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1789
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and AC004051.2 expression is measured. Determine whether AC004051.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXO4 is perturbed and AC004051.2 expression is measured. Determine whether AC004051.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1849
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of AC016629.3. Does perturbing PRTG lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PRTG and examine the expression of AC016629.3. Does perturbing PRTG lead to a significant change in AC016629.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3611
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Does this perturbation cause a significant change in RPS6KA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of RPS6KA2 is measured. Does this perturbation cause a significant change in RPS6KA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1600
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and SPANXD expression is measured. Determine whether SPANXD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIAA1804 is perturbed and SPANXD expression is measured. Determine whether SPANXD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4199
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of S100A3. Does this perturbation cause a significant change in S100A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of S100A3. Does this perturbation cause a significant change in S100A3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1914
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor CNN2 expression. Decide whether this perturbation leads to a significant alteration in CNN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor CNN2 expression. Decide whether this perturbation leads to a significant alteration in CNN2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4708
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5086
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Does this perturbation cause a significant change in INADL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of INADL is measured. Does this perturbation cause a significant change in INADL expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2250
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM118A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TP73, does the expression profile of FAM118A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2667
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3B is perturbed and CTB-161C1.1 expression is measured. Determine whether CTB-161C1.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1419
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, EGR1 is perturbed and the expression of BLVRB is measured. Determine whether BLVRB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6176
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of ID3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":247
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is quantified. Does this perturbation result in a significant change in COL18A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and COL18A1-AS1 expression is quantified. Does this perturbation result in a significant change in COL18A1-AS1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":632
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of IGDCC3. Does perturbing MAP4K3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of IGDCC3. Does perturbing MAP4K3 lead to a significant change in IGDCC3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2321
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of SLC31A2. Does this perturbation cause a significant change in SLC31A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1B and then measure expression of SLC31A2. Does this perturbation cause a significant change in SLC31A2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5414
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DLX2 is perturbed and the expression of TUBB2B is measured. Determine whether TUBB2B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1586
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and TMEM88 expression is quantified. Does this perturbation result in a significant change in TMEM88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and TMEM88 expression is quantified. Does this perturbation result in a significant change in TMEM88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5182
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor ESAM expression. Decide whether this perturbation leads to a significant alteration in ESAM expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5278
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Does this perturbation cause a significant change in DSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB25 is perturbed and the expression of DSC1 is measured. Does this perturbation cause a significant change in DSC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1290
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SET is perturbed and ZNF467 expression is quantified. Does this perturbation result in a significant change in ZNF467 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":872
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Does this perturbation cause a significant change in TAPBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of TAPBP is measured. Does this perturbation cause a significant change in TAPBP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2230
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Does this perturbation cause a significant change in TOX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of TOX is measured. Does this perturbation cause a significant change in TOX expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1360
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of MT1E. Does perturbing BCORL1 lead to a significant change in MT1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BCORL1 and examine the expression of MT1E. Does perturbing BCORL1 lead to a significant change in MT1E expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":361
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor S100A3 expression. Decide whether this perturbation leads to a significant alteration in S100A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor S100A3 expression. Decide whether this perturbation leads to a significant alteration in S100A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1918
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor AC006262.5 expression. Decide whether this perturbation leads to a significant alteration in AC006262.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4988
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and DEK expression is measured. Determine whether DEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and DEK expression is measured. Determine whether DEK exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1679
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LHX1 is perturbed and the expression of PAQR7 is measured. Does this perturbation cause a significant change in PAQR7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":990
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of S100A3. Does perturbing RHOXF2BB lead to a significant change in S100A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of S100A3. Does perturbing RHOXF2BB lead to a significant change in S100A3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1911
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is measured. Determine whether RP11-442O1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and RP11-442O1.4 expression is measured. Determine whether RP11-442O1.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4669
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of UBASH3A, does the expression profile of AC074289.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4857
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CD52 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6185
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ABCA6. Does perturbing KIAA1804 lead to a significant change in ABCA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of ABCA6. Does perturbing KIAA1804 lead to a significant change in ABCA6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4171
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of BCL2L11. Does this perturbation cause a significant change in BCL2L11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of BCL2L11. Does this perturbation cause a significant change in BCL2L11 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4924
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in MOGAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of JUN is associated with a significant change in MOGAT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5535
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of BCL2L11 is associated with a significant change in RP3-467K16.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4955
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of RP11-38J22.3. Does perturbing HK2 lead to a significant change in RP11-38J22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of RP11-38J22.3. Does perturbing HK2 lead to a significant change in RP11-38J22.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6071
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SDSL expression is quantified. Does this perturbation result in a significant change in SDSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SDSL expression is quantified. Does this perturbation result in a significant change in SDSL expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2422
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN13 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5635
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Does this perturbation cause a significant change in RP11-514P8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PLK4 is perturbed and the expression of RP11-514P8.2 is measured. Does this perturbation cause a significant change in RP11-514P8.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3690
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and PRTN3 expression is observed. Does this perturbation lead to a significant difference in PRTN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and PRTN3 expression is observed. Does this perturbation lead to a significant difference in PRTN3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1103
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of AC145110.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXB9, does the expression profile of AC145110.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3117
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and NCALD expression is measured. Determine whether NCALD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and NCALD expression is measured. Determine whether NCALD exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4839
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Determine whether RP11-567N4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, AHR is perturbed and the expression of RP11-567N4.3 is measured. Determine whether RP11-567N4.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1786
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LGALS1 expression is observed. Does this perturbation lead to a significant difference in LGALS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5813
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in RP1-102K2.6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1015
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ARID1A and then measure expression of CNN2. Does this perturbation cause a significant change in CNN2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4704
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AC034228.4. Does perturbing HNF4A lead to a significant change in AC034228.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AC034228.4. Does perturbing HNF4A lead to a significant change in AC034228.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4291
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AC034228.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AC034228.4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4297
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ESAM. Does perturbing ATL1 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of ESAM. Does perturbing ATL1 lead to a significant change in ESAM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5271
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of CTB-49A3.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of CTB-49A3.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3397
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CDK1 expression is observed. Does this perturbation lead to a significant difference in CDK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and CDK1 expression is observed. Does this perturbation lead to a significant difference in CDK1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4403
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and CEBPD expression is quantified. Does this perturbation result in a significant change in CEBPD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HK2 is perturbed and CEBPD expression is quantified. Does this perturbation result in a significant change in CEBPD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6062
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and LMNA expression is quantified. Does this perturbation result in a significant change in LMNA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and LMNA expression is quantified. Does this perturbation result in a significant change in LMNA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1682
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of CTA-384D8.34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of CTA-384D8.34 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":647
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and VGF expression is measured. Determine whether VGF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and VGF expression is measured. Determine whether VGF exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":269
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CRAT37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in CRAT37 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6195
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPA is perturbed and the expression of CD46 is measured. Determine whether CD46 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4206
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CTD-2378E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of CTD-2378E12.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6277
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Determine whether RGPD5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CITED1 is perturbed and the expression of RGPD5 is measured. Determine whether RGPD5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5966
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of FEV indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":927
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and SPANXD expression is quantified. Does this perturbation result in a significant change in SPANXD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and SPANXD expression is quantified. Does this perturbation result in a significant change in SPANXD expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4192
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and PHACTR1 expression is observed. Does this perturbation lead to a significant difference in PHACTR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IGDCC3 is perturbed and PHACTR1 expression is observed. Does this perturbation lead to a significant difference in PHACTR1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4383
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of HBE1. Does perturbing MEIS1 lead to a significant change in HBE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of HBE1. Does perturbing MEIS1 lead to a significant change in HBE1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":441
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and RP11-91A18.4 expression is quantified. Does this perturbation result in a significant change in RP11-91A18.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and RP11-91A18.4 expression is quantified. Does this perturbation result in a significant change in RP11-91A18.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2692
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of SOX4. Does this perturbation cause a significant change in SOX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of SOX4. Does this perturbation cause a significant change in SOX4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2354
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is measured. Determine whether RP3-510H16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP3-510H16.3 expression is measured. Determine whether RP3-510H16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3839
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LRRTM4 expression is observed. Does this perturbation lead to a significant difference in LRRTM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SNAI1 is perturbed and LRRTM4 expression is observed. Does this perturbation lead to a significant difference in LRRTM4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5843
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIF18B is perturbed and the expression of RP1-34B20.21 is measured. Does this perturbation cause a significant change in RP1-34B20.21 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6110
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Determine whether CCNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of CCNL1 is measured. Determine whether CCNL1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6146
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CRYM expression is measured. Determine whether CRYM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3849
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and BMP2K expression is quantified. Does this perturbation result in a significant change in BMP2K expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MIDN is perturbed and BMP2K expression is quantified. Does this perturbation result in a significant change in BMP2K expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1502
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of PRSS57 is measured. Determine whether PRSS57 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1156
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor VGF expression. Decide whether this perturbation leads to a significant alteration in VGF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ELMSAN1 and monitor VGF expression. Decide whether this perturbation leads to a significant alteration in VGF expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":268
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of PSMB8. Does this perturbation cause a significant change in PSMB8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAML2 and then measure expression of PSMB8. Does this perturbation cause a significant change in PSMB8 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":104
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and CST9L expression is measured. Determine whether CST9L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXA3 is perturbed and CST9L expression is measured. Determine whether CST9L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3339
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SNCG expression is measured. Determine whether SNCG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, S1PR2 is perturbed and SNCG expression is measured. Determine whether SNCG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1989
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LRRC74B expression is measured. Determine whether LRRC74B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LRRC74B expression is measured. Determine whether LRRC74B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4659
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and KRT79 expression is observed. Does this perturbation lead to a significant difference in KRT79 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which C3orf72 is perturbed and KRT79 expression is observed. Does this perturbation lead to a significant difference in KRT79 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3883
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MYOZ3. Does perturbing LYL1 lead to a significant change in MYOZ3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of MYOZ3. Does perturbing LYL1 lead to a significant change in MYOZ3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3941
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RGPD5 expression is measured. Determine whether RGPD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and RGPD5 expression is measured. Determine whether RGPD5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5969
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor RP11-505P4.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RREB1 and monitor RP11-505P4.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-505P4.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1138
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXB9 is perturbed and NCKAP1L expression is observed. Does this perturbation lead to a significant difference in NCKAP1L expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3083
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in TSC22D4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":195
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AP1S2. Does perturbing HNF4A lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HNF4A and examine the expression of AP1S2. Does perturbing HNF4A lead to a significant change in AP1S2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4261
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and TUBB expression is quantified. Does this perturbation result in a significant change in TUBB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and TUBB expression is quantified. Does this perturbation result in a significant change in TUBB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2642
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Does this perturbation cause a significant change in FAM83A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN13 is perturbed and the expression of FAM83A is measured. Does this perturbation cause a significant change in FAM83A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5620
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KMT2A is perturbed and the expression of TFAP2A-AS1 is measured. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4360
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and TRIM22 expression is observed. Does this perturbation lead to a significant difference in TRIM22 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4593
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of LGALS12. Does this perturbation cause a significant change in LGALS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DUSP9 and then measure expression of LGALS12. Does this perturbation cause a significant change in LGALS12 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":184
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of YPEL3. Does perturbing PTPN9 lead to a significant change in YPEL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of YPEL3. Does perturbing PTPN9 lead to a significant change in YPEL3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5751
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and HMGA2 expression is measured. Determine whether HMGA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and HMGA2 expression is measured. Determine whether HMGA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3899
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and SPARC expression is measured. Determine whether SPARC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, JUN is perturbed and SPARC expression is measured. Determine whether SPARC exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5529
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of IER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOSB, does the expression profile of IER3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2767
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LRRTM4 expression. Decide whether this perturbation leads to a significant alteration in LRRTM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor LRRTM4 expression. Decide whether this perturbation leads to a significant alteration in LRRTM4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5848
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of PIM2 is measured. Does this perturbation cause a significant change in PIM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5740
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Does this perturbation cause a significant change in LINC01395 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZBTB10 is perturbed and the expression of LINC01395 is measured. Does this perturbation cause a significant change in LINC01395 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5590
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3157
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and TLN1 expression is measured. Determine whether TLN1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1529
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of COTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of COTL1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1287
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IRF1 is perturbed and the expression of RP1-102K2.6 is measured. Does this perturbation cause a significant change in RP1-102K2.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2980
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and YPEL3 expression is measured. Determine whether YPEL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN9 is perturbed and YPEL3 expression is measured. Determine whether YPEL3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5759
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CTB-161C1.1. Does perturbing CEBPA lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CEBPA and examine the expression of CTB-161C1.1. Does perturbing CEBPA lead to a significant change in CTB-161C1.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4231
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IER5L and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2548
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-510J16.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC4A1, does the expression profile of RP11-510J16.5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1067
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPE is associated with a significant change in CCS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":135
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and RP11-290L1.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290L1.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and RP11-290L1.2 expression is observed. Does this perturbation lead to a significant difference in RP11-290L1.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2033
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TMSB4X and then measure expression of AC006262.5. Does this perturbation cause a significant change in AC006262.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4524
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of CCDC136. Does perturbing OSR2 lead to a significant change in CCDC136 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of CCDC136. Does perturbing OSR2 lead to a significant change in CCDC136 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5031
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of CAPG. Does perturbing NCL lead to a significant change in CAPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NCL and examine the expression of CAPG. Does perturbing NCL lead to a significant change in CAPG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4871
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, GLB1L2 is perturbed and the expression of CTNNB1 is measured. Determine whether CTNNB1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":506
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3B and monitor UBASH3B expression. Decide whether this perturbation leads to a significant alteration in UBASH3B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1408
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and HERPUD1 expression is measured. Determine whether HERPUD1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5829
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and GRN expression is quantified. Does this perturbation result in a significant change in GRN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5882
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNN1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2125
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and AIM1 expression is measured. Determine whether AIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXC13 is perturbed and AIM1 expression is measured. Determine whether AIM1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3129
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HHEX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SAMD1, does the expression profile of HHEX indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3387
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SLC20A1 expression is observed. Does this perturbation lead to a significant difference in SLC20A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN1 is perturbed and SLC20A1 expression is observed. Does this perturbation lead to a significant difference in SLC20A1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2403
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Does this perturbation cause a significant change in RP11-646I6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of RP11-646I6.6 is measured. Does this perturbation cause a significant change in RP11-646I6.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1070
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of CCNJL. Does this perturbation cause a significant change in CCNJL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of CCNJL. Does this perturbation cause a significant change in CCNJL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5124
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Does this perturbation cause a significant change in AGXT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC4A1 is perturbed and the expression of AGXT is measured. Does this perturbation cause a significant change in AGXT expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1050
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Determine whether IGHEP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB1 is perturbed and the expression of IGHEP2 is measured. Determine whether IGHEP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3586
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and AC006262.5 expression is quantified. Does this perturbation result in a significant change in AC006262.5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":492
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and RASGRF2 expression is observed. Does this perturbation lead to a significant difference in RASGRF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and RASGRF2 expression is observed. Does this perturbation lead to a significant difference in RASGRF2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1543
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXO4, does the expression profile of CDC20 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1817
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and CEBPA expression is quantified. Does this perturbation result in a significant change in CEBPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBFA2T3 is perturbed and CEBPA expression is quantified. Does this perturbation result in a significant change in CEBPA expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1632
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Determine whether LGALS12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Determine whether LGALS12 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":186
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Does this perturbation cause a significant change in KRTAP9-9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ATL1 is perturbed and the expression of KRTAP9-9 is measured. Does this perturbation cause a significant change in KRTAP9-9 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5290
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of VMP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of VMP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5867
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXB9 and then measure expression of SAT2. Does this perturbation cause a significant change in SAT2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3074
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of BMP2K. Does this perturbation cause a significant change in BMP2K expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of BMP2K. Does this perturbation cause a significant change in BMP2K expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1504
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, S1PR2 is perturbed and the expression of SLC2A1-AS1 is measured. Does this perturbation cause a significant change in SLC2A1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1990
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor AC004051.2 expression. Decide whether this perturbation leads to a significant alteration in AC004051.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXO4 and monitor AC004051.2 expression. Decide whether this perturbation leads to a significant alteration in AC004051.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1848
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Does this perturbation cause a significant change in TPH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SAMD1 is perturbed and the expression of TPH2 is measured. Does this perturbation cause a significant change in TPH2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3410
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of DNAJB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of DNAJB1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3867
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TMSB4X, does the expression profile of PHGDH indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4507
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CDK1. Does perturbing IGDCC3 lead to a significant change in CDK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CDK1. Does perturbing IGDCC3 lead to a significant change in CDK1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4401
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and SPARC expression is observed. Does this perturbation lead to a significant difference in SPARC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which JUN is perturbed and SPARC expression is observed. Does this perturbation lead to a significant difference in SPARC expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5523
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TBX3 and then measure expression of FEV. Does this perturbation cause a significant change in FEV expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":924
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CCS expression is measured. Determine whether CCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CEBPE is perturbed and CCS expression is measured. Determine whether CCS exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":139
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CARMN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in CARMN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3275
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of PLEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SPI1, does the expression profile of PLEK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5097
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C8orf22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RHOXF2BB, does the expression profile of C8orf22 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1897
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor C10orf11 expression. Decide whether this perturbation leads to a significant alteration in C10orf11 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4968
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LINC01562 expression is quantified. Does this perturbation result in a significant change in LINC01562 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB25 is perturbed and LINC01562 expression is quantified. Does this perturbation result in a significant change in LINC01562 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1312
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of PHACTR1. Does perturbing IGDCC3 lead to a significant change in PHACTR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of PHACTR1. Does perturbing IGDCC3 lead to a significant change in PHACTR1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4381
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Determine whether MACF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ARID1A is perturbed and the expression of MACF1 is measured. Determine whether MACF1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4736
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in RP11-202A13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CNNM4 is associated with a significant change in RP11-202A13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4785
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of FABP5 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4327
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of GLB1L2 is associated with a significant change in RABGAP1L expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":485
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RNF168. Does this perturbation cause a significant change in RNF168 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of RNF168. Does this perturbation cause a significant change in RNF168 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":774
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of CAPG. Does this perturbation cause a significant change in CAPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of CAPG. Does this perturbation cause a significant change in CAPG expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4874
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in COTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in COTL1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1285
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-646I6.6. Does this perturbation cause a significant change in RP11-646I6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-646I6.6. Does this perturbation cause a significant change in RP11-646I6.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1074
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is quantified. Does this perturbation result in a significant change in CTC-492K19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is quantified. Does this perturbation result in a significant change in CTC-492K19.4 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1122
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HK2 and then measure expression of MFSD2A. Does this perturbation cause a significant change in MFSD2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6094
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to UBASH3B and then measure expression of NKG7. Does this perturbation cause a significant change in NKG7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1384
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in RP11-38J22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HK2 is associated with a significant change in RP11-38J22.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6075
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor STRC expression. Decide whether this perturbation leads to a significant alteration in STRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor STRC expression. Decide whether this perturbation leads to a significant alteration in STRC expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5908
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor C1orf162 expression. Decide whether this perturbation leads to a significant alteration in C1orf162 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXF1 and monitor C1orf162 expression. Decide whether this perturbation leads to a significant alteration in C1orf162 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3538
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP4K3 and monitor IGDCC3 expression. Decide whether this perturbation leads to a significant alteration in IGDCC3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2328
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of AIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXC13, does the expression profile of AIM1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3127
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Determine whether RSPO4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of RSPO4 is measured. Determine whether RSPO4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4116
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LINC01562 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB25, does the expression profile of LINC01562 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1317
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CTD-3131K8.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP7D1 is associated with a significant change in CTD-3131K8.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2755
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ABCA13 expression is measured. Determine whether ABCA13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and ABCA13 expression is measured. Determine whether ABCA13 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2099
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor PROX1 expression. Decide whether this perturbation leads to a significant alteration in PROX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor PROX1 expression. Decide whether this perturbation leads to a significant alteration in PROX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4058
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ARL6IP1. Does perturbing C19orf26 lead to a significant change in ARL6IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ARL6IP1. Does perturbing C19orf26 lead to a significant change in ARL6IP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2931
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Does this perturbation cause a significant change in ORAI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of ORAI3 is measured. Does this perturbation cause a significant change in ORAI3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1940
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in TACC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in TACC1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6005
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of BST2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1937
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Determine whether ITGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of ITGA3 is measured. Determine whether ITGA3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4136
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PAMR1 expression is measured. Determine whether PAMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PAMR1 expression is measured. Determine whether PAMR1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4799
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SNCG. Does perturbing S1PR2 lead to a significant change in SNCG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb S1PR2 and examine the expression of SNCG. Does perturbing S1PR2 lead to a significant change in SNCG expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1981
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Determine whether PXK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of PXK is measured. Determine whether PXK shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2176
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Does this perturbation cause a significant change in PERM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of PERM1 is measured. Does this perturbation cause a significant change in PERM1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5480
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CENPE expression is measured. Determine whether CENPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and CENPE expression is measured. Determine whether CENPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6229
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in FAM19A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in FAM19A2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3365
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Does this perturbation cause a significant change in LINC01227 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of LINC01227 is measured. Does this perturbation cause a significant change in LINC01227 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5430
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXL2 is perturbed and the expression of FADS1 is measured. Determine whether FADS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4106
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Determine whether IGFL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of IGFL2 is measured. Determine whether IGFL2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5496
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Does this perturbation cause a significant change in ADGRF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC38A2 is perturbed and the expression of ADGRF1 is measured. Does this perturbation cause a significant change in ADGRF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5720
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Does this perturbation cause a significant change in HBG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1B is perturbed and the expression of HBG1 is measured. Does this perturbation cause a significant change in HBG1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5380
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor CHST15 expression. Decide whether this perturbation leads to a significant alteration in CHST15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor CHST15 expression. Decide whether this perturbation leads to a significant alteration in CHST15 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2498
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of AHR is associated with a significant change in FAM178B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1745
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Does this perturbation cause a significant change in CTSW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, NIT1 is perturbed and the expression of CTSW is measured. Does this perturbation cause a significant change in CTSW expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5360
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CITED1 is perturbed and HMOX1 expression is measured. Determine whether HMOX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5979
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and RP3-525N10.2 expression is observed. Does this perturbation lead to a significant difference in RP3-525N10.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXA13 is perturbed and RP3-525N10.2 expression is observed. Does this perturbation lead to a significant difference in RP3-525N10.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5893
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and IL1RN expression is measured. Determine whether IL1RN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CELF2 is perturbed and IL1RN expression is measured. Determine whether IL1RN exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2199
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CMB9-22P13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of CMB9-22P13.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5397
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor NPW expression. Decide whether this perturbation leads to a significant alteration in NPW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HK2 and monitor NPW expression. Decide whether this perturbation leads to a significant alteration in NPW expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6048
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in CTSS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in CTSS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2025
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZNF318 and then measure expression of FAM101B. Does this perturbation cause a significant change in FAM101B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1144
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Determine whether SLC22A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of SLC22A11 is measured. Determine whether SLC22A11 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4306
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4162
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of CALY indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of DLX2, does the expression profile of CALY indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1597
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of MOGAT2. Does perturbing JUN lead to a significant change in MOGAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of MOGAT2. Does perturbing JUN lead to a significant change in MOGAT2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5531
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and CTC-490E21.10 expression is observed. Does this perturbation lead to a significant difference in CTC-490E21.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KLF1 is perturbed and CTC-490E21.10 expression is observed. Does this perturbation lead to a significant difference in CTC-490E21.10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":573
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of LHX1 is measured. Determine whether LHX1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":616
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ATF6B expression is quantified. Does this perturbation result in a significant change in ATF6B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NIT1 is perturbed and ATF6B expression is quantified. Does this perturbation result in a significant change in ATF6B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5322
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and RABAC1 expression is quantified. Does this perturbation result in a significant change in RABAC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and RABAC1 expression is quantified. Does this perturbation result in a significant change in RABAC1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5142
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD47 expression is measured. Determine whether CD47 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ETS2 is perturbed and CD47 expression is measured. Determine whether CD47 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":789
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CNN1 is perturbed and BLVRB expression is observed. Does this perturbation lead to a significant difference in BLVRB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2123
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MEIS1 is perturbed and PRSS57 expression is observed. Does this perturbation lead to a significant difference in PRSS57 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":423
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-497G19.7 expression is observed. Does this perturbation lead to a significant difference in RP11-497G19.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL2A1 is perturbed and RP11-497G19.7 expression is observed. Does this perturbation lead to a significant difference in RP11-497G19.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1253
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of FAM178B is measured. Determine whether FAM178B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2606
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ETS1 expression is measured. Determine whether ETS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KLF1 is perturbed and ETS1 expression is measured. Determine whether ETS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":589
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Does this perturbation cause a significant change in GRAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of GRAP2 is measured. Does this perturbation cause a significant change in GRAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":310
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor SCG5 expression. Decide whether this perturbation leads to a significant alteration in SCG5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SNAI1 and monitor SCG5 expression. Decide whether this perturbation leads to a significant alteration in SCG5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5858
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, BAK1 is perturbed and LHX1 expression is quantified. Does this perturbation result in a significant change in LHX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":612
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CTD-2378E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CTD-2378E12.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6275
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TGFBR2 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5453
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Does this perturbation cause a significant change in RASGRF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MIDN is perturbed and the expression of RASGRF2 is measured. Does this perturbation cause a significant change in RASGRF2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1540
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of MTURN. Does perturbing RHOXF2BB lead to a significant change in MTURN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RHOXF2BB and examine the expression of MTURN. Does perturbing RHOXF2BB lead to a significant change in MTURN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1881
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of PHLDA2. Does this perturbation cause a significant change in PHLDA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3304
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and RSPO4 expression is observed. Does this perturbation lead to a significant difference in RSPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXL2 is perturbed and RSPO4 expression is observed. Does this perturbation lead to a significant difference in RSPO4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4113
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor AC078941.1 expression. Decide whether this perturbation leads to a significant alteration in AC078941.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor AC078941.1 expression. Decide whether this perturbation leads to a significant alteration in AC078941.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2018
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB10 is perturbed and CSF3R expression is observed. Does this perturbation lead to a significant difference in CSF3R expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5573
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF2C is perturbed and the expression of AC006262.5 is measured. Determine whether AC006262.5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4576
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb OSR2 and monitor SKAP2 expression. Decide whether this perturbation leads to a significant alteration in SKAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5048
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":879
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of COL1A1 is associated with a significant change in SOCS3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3455
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C8orf22 expression. Decide whether this perturbation leads to a significant alteration in C8orf22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RHOXF2BB and monitor C8orf22 expression. Decide whether this perturbation leads to a significant alteration in C8orf22 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1898
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD47 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ETS2, does the expression profile of CD47 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":787
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RUNX1T1 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1933
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IRF1 and then measure expression of RP1-102K2.6. Does this perturbation cause a significant change in RP1-102K2.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2984
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of IFIT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of IFIT2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6027
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AC007246.3. Does perturbing MAP4K3 lead to a significant change in AC007246.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP4K3 and examine the expression of AC007246.3. Does perturbing MAP4K3 lead to a significant change in AC007246.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2291
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CKS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of POU3F2 is associated with a significant change in CKS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2075
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in TPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in TPH2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3415
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ARL6IP1 is measured. Determine whether ARL6IP1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2936
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and SCG5 expression is measured. Determine whether SCG5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SNAI1 is perturbed and SCG5 expression is measured. Determine whether SCG5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5859
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is measured. Determine whether PCDHGA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB25 is perturbed and PCDHGA6 expression is measured. Determine whether PCDHGA6 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1309
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TPP1. Does perturbing DLX2 lead to a significant change in TPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TPP1. Does perturbing DLX2 lead to a significant change in TPP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1571
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CCNB1 expression is measured. Determine whether CCNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and CCNB1 expression is measured. Determine whether CCNB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3859
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor RP11-180M15.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-180M15.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor RP11-180M15.6 expression. Decide whether this perturbation leads to a significant alteration in RP11-180M15.6 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4438
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Does this perturbation cause a significant change in UCKL1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPB is perturbed and the expression of UCKL1-AS1 is measured. Does this perturbation cause a significant change in UCKL1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5250
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CCDC159 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPA, does the expression profile of CCDC159 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4257
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of IL1RN. Does perturbing CELF2 lead to a significant change in IL1RN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of IL1RN. Does perturbing CELF2 lead to a significant change in IL1RN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2191
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is quantified. Does this perturbation result in a significant change in CMB9-22P13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1B is perturbed and CMB9-22P13.1 expression is quantified. Does this perturbation result in a significant change in CMB9-22P13.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5392
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and CLTA expression is observed. Does this perturbation lead to a significant difference in CLTA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP2K6 is perturbed and CLTA expression is observed. Does this perturbation lead to a significant difference in CLTA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3993
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of FAM46C. Does this perturbation cause a significant change in FAM46C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of FAM46C. Does this perturbation cause a significant change in FAM46C expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2894
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01227 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1B, does the expression profile of LINC01227 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5437
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CIB3 expression. Decide whether this perturbation leads to a significant alteration in CIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPB and monitor CIB3 expression. Decide whether this perturbation leads to a significant alteration in CIB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5228
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of CST3. Does perturbing LHX1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of CST3. Does perturbing LHX1 lead to a significant change in CST3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":971
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Does this perturbation cause a significant change in AC139099.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL1A1 is perturbed and the expression of AC139099.6 is measured. Does this perturbation cause a significant change in AC139099.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3470
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and GYPE expression is measured. Determine whether GYPE exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4759
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor PKIG expression. Decide whether this perturbation leads to a significant alteration in PKIG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor PKIG expression. Decide whether this perturbation leads to a significant alteration in PKIG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":208
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CD37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of CD37 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3247
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of SKAP2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":967
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Determine whether PLA2G16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KIF18B is perturbed and the expression of PLA2G16 is measured. Determine whether PLA2G16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6156
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ANXA2R. Does this perturbation cause a significant change in ANXA2R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXA13 and then measure expression of ANXA2R. Does this perturbation cause a significant change in ANXA2R expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5874
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor RP3-525N10.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-525N10.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor RP3-525N10.2 expression. Decide whether this perturbation leads to a significant alteration in RP3-525N10.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5898
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN12 is associated with a significant change in NKG7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2595
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-290K4.2. Does perturbing PLK4 lead to a significant change in RP11-290K4.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-290K4.2. Does perturbing PLK4 lead to a significant change in RP11-290K4.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3701
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3507
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is quantified. Does this perturbation result in a significant change in RP11-537H15.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is quantified. Does this perturbation result in a significant change in RP11-537H15.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2272
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and RP11-362K14.7 expression is observed. Does this perturbation lead to a significant difference in RP11-362K14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and RP11-362K14.7 expression is observed. Does this perturbation lead to a significant difference in RP11-362K14.7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4183
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of RP11-452C8.1. Does this perturbation cause a significant change in RP11-452C8.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SGK1 and then measure expression of RP11-452C8.1. Does this perturbation cause a significant change in RP11-452C8.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4074
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Does this perturbation cause a significant change in AKAP13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K6 is perturbed and the expression of AKAP13 is measured. Does this perturbation cause a significant change in AKAP13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3980
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Determine whether AMPH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of AMPH is measured. Determine whether AMPH shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6016
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in CCNJL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SPI1 is associated with a significant change in CCNJL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5125
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP11-345P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in RP11-345P4.7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2875
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of TUBB. Does this perturbation cause a significant change in TUBB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TP73 and then measure expression of TUBB. Does this perturbation cause a significant change in TUBB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2644
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of RP11-369K17.1. Does perturbing TGFBR2 lead to a significant change in RP11-369K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TGFBR2 and examine the expression of RP11-369K17.1. Does perturbing TGFBR2 lead to a significant change in RP11-369K17.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5471
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of RP11-290L1.2. Does this perturbation cause a significant change in RP11-290L1.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to S1PR2 and then measure expression of RP11-290L1.2. Does this perturbation cause a significant change in RP11-290L1.2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2034
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and RABAC1 expression is measured. Determine whether RABAC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and RABAC1 expression is measured. Determine whether RABAC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5149
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is quantified. Does this perturbation result in a significant change in RP11-259K5.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is quantified. Does this perturbation result in a significant change in RP11-259K5.1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1242
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and MACF1 expression is measured. Determine whether MACF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARID1A is perturbed and MACF1 expression is measured. Determine whether MACF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4739
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and FEV expression is observed. Does this perturbation lead to a significant difference in FEV expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1323
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and VCX3B expression is quantified. Does this perturbation result in a significant change in VCX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and VCX3B expression is quantified. Does this perturbation result in a significant change in VCX3B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":152
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CCNL1. Does perturbing KIF18B lead to a significant change in CCNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of CCNL1. Does perturbing KIF18B lead to a significant change in CCNL1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6141
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of AC007193.6. Does this perturbation cause a significant change in AC007193.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN12 and then measure expression of AC007193.6. Does this perturbation cause a significant change in AC007193.6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2634
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-497G19.7. Does perturbing COL2A1 lead to a significant change in RP11-497G19.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb COL2A1 and examine the expression of RP11-497G19.7. Does perturbing COL2A1 lead to a significant change in RP11-497G19.7 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1251
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in NUMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CLDN6 is associated with a significant change in NUMB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3265
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPA is perturbed and AP1S2 expression is quantified. Does this perturbation result in a significant change in AP1S2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4212
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of RNF213 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4477
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and KRTAP9-9 expression is measured. Determine whether KRTAP9-9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and KRTAP9-9 expression is measured. Determine whether KRTAP9-9 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5299
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and PGA4 expression is observed. Does this perturbation lead to a significant difference in PGA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRDM1 is perturbed and PGA4 expression is observed. Does this perturbation lead to a significant difference in PGA4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6033
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, UBASH3A is perturbed and UBASH3A expression is measured. Determine whether UBASH3A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4829
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Does this perturbation cause a significant change in APOBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of APOBR is measured. Does this perturbation cause a significant change in APOBR expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5170
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor LEFTY2 expression. Decide whether this perturbation leads to a significant alteration in LEFTY2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BCL2L11 and monitor LEFTY2 expression. Decide whether this perturbation leads to a significant alteration in LEFTY2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4948
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MEIS1 is perturbed and PRSS57 expression is quantified. Does this perturbation result in a significant change in PRSS57 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":422
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Does this perturbation cause a significant change in ANXA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAPK1 is perturbed and the expression of ANXA5 is measured. Does this perturbation cause a significant change in ANXA5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2850
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CHI3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":905
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C3orf72 and then measure expression of CRYM. Does this perturbation cause a significant change in CRYM expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3844
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN9, does the expression profile of PIM2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5747
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ADGRF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC38A2 is associated with a significant change in ADGRF1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5725
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of RP4-565E6.1. Does this perturbation cause a significant change in RP4-565E6.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of RP4-565E6.1. Does this perturbation cause a significant change in RP4-565E6.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":294
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Does this perturbation cause a significant change in RP11-109E24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of RP11-109E24.2 is measured. Does this perturbation cause a significant change in RP11-109E24.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6210
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ICAM4. Does perturbing CNNM4 lead to a significant change in ICAM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of ICAM4. Does perturbing CNNM4 lead to a significant change in ICAM4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4741
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LHX1 is perturbed and the expression of RP1-102K2.6 is measured. Determine whether RP1-102K2.6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1016
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of RP1-59D14.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of RP1-59D14.10 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3777
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MIDN is perturbed and the expression of TLN1 is measured. Determine whether TLN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1526
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of IL20. Does perturbing BPGM lead to a significant change in IL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb BPGM and examine the expression of IL20. Does perturbing BPGM lead to a significant change in IL20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3761
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Determine whether ACP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Determine whether ACP5 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1206
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor FAM101B expression. Decide whether this perturbation leads to a significant alteration in FAM101B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":308
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of ALAS2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6237
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in PDE1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in PDE1B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":35
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of AIM1. Does this perturbation cause a significant change in AIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of AIM1. Does this perturbation cause a significant change in AIM1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3124
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is measured. Determine whether CTB-49A3.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SAMD1 is perturbed and CTB-49A3.5 expression is measured. Determine whether CTB-49A3.5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3399
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of PRSS57 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4167
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLA2G16 expression is quantified. Does this perturbation result in a significant change in PLA2G16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIF18B is perturbed and PLA2G16 expression is quantified. Does this perturbation result in a significant change in PLA2G16 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6152
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of AC074289.1 is measured. Does this perturbation cause a significant change in AC074289.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1610
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in GCM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in GCM2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1355
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ATL1 is perturbed and ESAM expression is measured. Determine whether ESAM exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5279
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of RNF182. Does perturbing LYL1 lead to a significant change in RNF182 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LYL1 and examine the expression of RNF182. Does perturbing LYL1 lead to a significant change in RNF182 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3951
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in SPANXD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIAA1804 is associated with a significant change in SPANXD expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4195
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and TMEM154 expression is quantified. Does this perturbation result in a significant change in TMEM154 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KIAA1804 is perturbed and TMEM154 expression is quantified. Does this perturbation result in a significant change in TMEM154 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4142
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLA2G16 expression is measured. Determine whether PLA2G16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and PLA2G16 expression is measured. Determine whether PLA2G16 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6159
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP7D1 is perturbed and the expression of MAP7D1 is measured. Does this perturbation cause a significant change in MAP7D1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2720
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SLC20A1 expression is measured. Determine whether SLC20A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SLC20A1 expression is measured. Determine whether SLC20A1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2409
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Does this perturbation cause a significant change in RP11-452C8.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SGK1 is perturbed and the expression of RP11-452C8.1 is measured. Does this perturbation cause a significant change in RP11-452C8.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4070
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb KIF2C and monitor KIF2C expression. Decide whether this perturbation leads to a significant alteration in KIF2C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4568
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KLF1 and then measure expression of FCGR2A. Does this perturbation cause a significant change in FCGR2A expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":544
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of AC074289.1. Does perturbing UBASH3A lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb UBASH3A and examine the expression of AC074289.1. Does perturbing UBASH3A lead to a significant change in AC074289.1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4851
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIPK1-AS1. Does perturbing CKS1B lead to a significant change in HIPK1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CKS1B and examine the expression of HIPK1-AS1. Does perturbing CKS1B lead to a significant change in HIPK1-AS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3221
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SNAI1, does the expression profile of HERPUD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5827
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SPI1 is perturbed and the expression of ZMAT3 is measured. Does this perturbation cause a significant change in ZMAT3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5130
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TBX3 is perturbed and the expression of CHI3L2 is measured. Does this perturbation cause a significant change in CHI3L2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":900
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of CST9L. Does this perturbation cause a significant change in CST9L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA3 and then measure expression of CST9L. Does this perturbation cause a significant change in CST9L expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3334
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PPFIA4. Does this perturbation cause a significant change in PPFIA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ATL1 and then measure expression of PPFIA4. Does this perturbation cause a significant change in PPFIA4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5304
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ACTC1 expression is measured. Determine whether ACTC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and ACTC1 expression is measured. Determine whether ACTC1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5379
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ARMCX3 expression is measured. Determine whether ARMCX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and ARMCX3 expression is measured. Determine whether ARMCX3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3979
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in RP11-76E17.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXA3 is associated with a significant change in RP11-76E17.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3345
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Does this perturbation cause a significant change in RP11-244F12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TMSB4X is perturbed and the expression of RP11-244F12.2 is measured. Does this perturbation cause a significant change in RP11-244F12.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4530
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC6A9 and monitor BTG2 expression. Decide whether this perturbation leads to a significant alteration in BTG2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1468
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of MAOB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of MAOB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1497
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LGALS1 is measured. Does this perturbation cause a significant change in LGALS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4630
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and FLJ12825 expression is quantified. Does this perturbation result in a significant change in FLJ12825 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CEBPE is perturbed and FLJ12825 expression is quantified. Does this perturbation result in a significant change in FLJ12825 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":172
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and LMNA expression is measured. Determine whether LMNA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HES7 is perturbed and LMNA expression is measured. Determine whether LMNA exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1689
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, AHR is perturbed and the expression of FAM178B is measured. Does this perturbation cause a significant change in FAM178B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1740
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3789
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of VGF. Does perturbing ELMSAN1 lead to a significant change in VGF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ELMSAN1 and examine the expression of VGF. Does perturbing ELMSAN1 lead to a significant change in VGF expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":261
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and TUBB3 expression is measured. Determine whether TUBB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and TUBB3 expression is measured. Determine whether TUBB3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3599
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and RP11-635N19.1 expression is observed. Does this perturbation lead to a significant difference in RP11-635N19.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and RP11-635N19.1 expression is observed. Does this perturbation lead to a significant difference in RP11-635N19.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1373
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and TCAF2 expression is quantified. Does this perturbation result in a significant change in TCAF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IRF1 is perturbed and TCAF2 expression is quantified. Does this perturbation result in a significant change in TCAF2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2972
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ZNF677 expression is measured. Determine whether ZNF677 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HOXB9 is perturbed and ZNF677 expression is measured. Determine whether ZNF677 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3099
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZNF318 is perturbed and PAQR7 expression is observed. Does this perturbation lead to a significant difference in PAQR7 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1183
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TFAP2A-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KMT2A, does the expression profile of TFAP2A-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4367
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and C1orf228 expression is quantified. Does this perturbation result in a significant change in C1orf228 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RREB1 is perturbed and C1orf228 expression is quantified. Does this perturbation result in a significant change in C1orf228 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1112
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TRIM31. Does perturbing MEIS1 lead to a significant change in TRIM31 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MEIS1 and examine the expression of TRIM31. Does perturbing MEIS1 lead to a significant change in TRIM31 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":461
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IRF1 is perturbed and AFMID expression is measured. Determine whether AFMID exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2969
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of CISH. Does perturbing PTPN12 lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of CISH. Does perturbing PTPN12 lead to a significant change in CISH expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2581
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of IER3. Does this perturbation cause a significant change in IER3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of IER3. Does this perturbation cause a significant change in IER3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2764
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and KIF2C expression is observed. Does this perturbation lead to a significant difference in KIF2C expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4563
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Determine whether CTD-3037G24.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of CTD-3037G24.4 is measured. Determine whether CTD-3037G24.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1436
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CARMN expression is quantified. Does this perturbation result in a significant change in CARMN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CLDN6 is perturbed and CARMN expression is quantified. Does this perturbation result in a significant change in CARMN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3272
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Does this perturbation cause a significant change in RP11-180M15.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of RP11-180M15.6 is measured. Does this perturbation cause a significant change in RP11-180M15.6 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4430
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRTG is perturbed and the expression of AC016629.3 is measured. Determine whether AC016629.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3616
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FEV is perturbed and C10orf11 expression is quantified. Does this perturbation result in a significant change in C10orf11 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":672
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Does this perturbation cause a significant change in RP3-525N10.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Does this perturbation cause a significant change in RP3-525N10.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5890
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Does this perturbation cause a significant change in SCG5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of SCG5 is measured. Does this perturbation cause a significant change in SCG5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5850
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is measured. Determine whether RP11-6D1.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K6 is perturbed and RP11-6D1.3 expression is measured. Determine whether RP11-6D1.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4019
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Determine whether HOXB6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of HOXB6 is measured. Determine whether HOXB6 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":816
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of C1orf162. Does this perturbation cause a significant change in C1orf162 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXF1 and then measure expression of C1orf162. Does this perturbation cause a significant change in C1orf162 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3534
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-514P8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-514P8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PLK4 and monitor RP11-514P8.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-514P8.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3698
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Does this perturbation cause a significant change in MYC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of MYC is measured. Does this perturbation cause a significant change in MYC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3020
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZNF318 is perturbed and FAM101B expression is quantified. Does this perturbation result in a significant change in FAM101B expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1142
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-567N4.3 expression is quantified. Does this perturbation result in a significant change in RP11-567N4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, AHR is perturbed and RP11-567N4.3 expression is quantified. Does this perturbation result in a significant change in RP11-567N4.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1782
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and CSRNP1 expression is quantified. Does this perturbation result in a significant change in CSRNP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CSRNP1 is perturbed and CSRNP1 expression is quantified. Does this perturbation result in a significant change in CSRNP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4642
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor HBE1 expression. Decide whether this perturbation leads to a significant alteration in HBE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor HBE1 expression. Decide whether this perturbation leads to a significant alteration in HBE1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":448
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of RAB5B. Does perturbing FEV lead to a significant change in RAB5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of RAB5B. Does perturbing FEV lead to a significant change in RAB5B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":681
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CMB9-22P13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in CMB9-22P13.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5395
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TM6SF2. Does perturbing KMT2A lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of TM6SF2. Does perturbing KMT2A lead to a significant change in TM6SF2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4371
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor LGALS12 expression. Decide whether this perturbation leads to a significant alteration in LGALS12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor LGALS12 expression. Decide whether this perturbation leads to a significant alteration in LGALS12 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":188
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Does this perturbation cause a significant change in MYLIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of MYLIP is measured. Does this perturbation cause a significant change in MYLIP expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1230
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and GRAP2 expression is observed. Does this perturbation lead to a significant difference in GRAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA1 is perturbed and GRAP2 expression is observed. Does this perturbation lead to a significant difference in GRAP2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":313
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Determine whether CTD-2616J11.16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZNF318 is perturbed and the expression of CTD-2616J11.16 is measured. Determine whether CTD-2616J11.16 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1196
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor RP11-6D1.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-6D1.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor RP11-6D1.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-6D1.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4018
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and C1orf141 expression is quantified. Does this perturbation result in a significant change in C1orf141 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K3 is perturbed and C1orf141 expression is quantified. Does this perturbation result in a significant change in C1orf141 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2332
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CD59 expression. Decide whether this perturbation leads to a significant alteration in CD59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CDKN1A and monitor CD59 expression. Decide whether this perturbation leads to a significant alteration in CD59 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2378
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and MAOB expression is observed. Does this perturbation lead to a significant difference in MAOB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and MAOB expression is observed. Does this perturbation lead to a significant difference in MAOB expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1493
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and VMP1 expression is quantified. Does this perturbation result in a significant change in VMP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXA13 is perturbed and VMP1 expression is quantified. Does this perturbation result in a significant change in VMP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5862
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor DDX58 expression. Decide whether this perturbation leads to a significant alteration in DDX58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DUSP9 and monitor DDX58 expression. Decide whether this perturbation leads to a significant alteration in DDX58 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":228
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Does this perturbation cause a significant change in TMEM154 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of TMEM154 is measured. Does this perturbation cause a significant change in TMEM154 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4140
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of PHLDA2. Does perturbing FOXA3 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of PHLDA2. Does perturbing FOXA3 lead to a significant change in PHLDA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3301
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in EMP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of IKZF3 is associated with a significant change in EMP3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3035
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of TYROBP. Does perturbing KLF1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of TYROBP. Does perturbing KLF1 lead to a significant change in TYROBP expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":561
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BAK1 is perturbed and the expression of BAK1 is measured. Determine whether BAK1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":626
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb RUNX1T1 and monitor UBASH3A expression. Decide whether this perturbation leads to a significant alteration in UBASH3A expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1958
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and SSTR3 expression is quantified. Does this perturbation result in a significant change in SSTR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HOXC13 is perturbed and SSTR3 expression is quantified. Does this perturbation result in a significant change in SSTR3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3172
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to LHX1 and then measure expression of PAQR7. Does this perturbation cause a significant change in PAQR7 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":994
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and KRTAP9-9 expression is quantified. Does this perturbation result in a significant change in KRTAP9-9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and KRTAP9-9 expression is quantified. Does this perturbation result in a significant change in KRTAP9-9 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5292
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Determine whether TRGVA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of TRGVA is measured. Determine whether TRGVA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":956
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Determine whether RP11-662J14.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CEBPB is perturbed and the expression of RP11-662J14.2 is measured. Determine whether RP11-662J14.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5246
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CCDC159 expression is observed. Does this perturbation lead to a significant difference in CCDC159 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPA is perturbed and CCDC159 expression is observed. Does this perturbation lead to a significant difference in CCDC159 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4253
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor RP11-290L1.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290L1.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor RP11-290L1.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-290L1.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2038
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBL is perturbed and ID1 expression is measured. Determine whether ID1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":749
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Does this perturbation cause a significant change in RP11-445F12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BAK1 is perturbed and the expression of RP11-445F12.1 is measured. Does this perturbation cause a significant change in RP11-445F12.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":600
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXA1 and then measure expression of AC016629.3. Does this perturbation cause a significant change in AC016629.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":324
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb C19orf26 and monitor ATP10D expression. Decide whether this perturbation leads to a significant alteration in ATP10D expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2928
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Determine whether SLC4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HK2 is perturbed and the expression of SLC4A3 is measured. Determine whether SLC4A3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6086
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CKS2. Does this perturbation cause a significant change in CKS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to POU3F2 and then measure expression of CKS2. Does this perturbation cause a significant change in CKS2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2074
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is measured. Determine whether RP11-514P8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PLK4 is perturbed and RP11-514P8.2 expression is measured. Determine whether RP11-514P8.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3699
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of RP11-362K14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of RP11-362K14.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4187
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor BMP2K expression. Decide whether this perturbation leads to a significant alteration in BMP2K expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor BMP2K expression. Decide whether this perturbation leads to a significant alteration in BMP2K expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1508
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of MME indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of MME indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6267
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CYP2C18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX3, does the expression profile of CYP2C18 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":937
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and TFRC expression is quantified. Does this perturbation result in a significant change in TFRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and TFRC expression is quantified. Does this perturbation result in a significant change in TFRC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1222
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and SOCS3 expression is measured. Determine whether SOCS3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3459
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ATP8B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MIDN, does the expression profile of ATP8B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1557
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor TUBB3 expression. Decide whether this perturbation leads to a significant alteration in TUBB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor TUBB3 expression. Decide whether this perturbation leads to a significant alteration in TUBB3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3598
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1C is associated with a significant change in CDC45 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6245
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor RETN expression. Decide whether this perturbation leads to a significant alteration in RETN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN1 and monitor RETN expression. Decide whether this perturbation leads to a significant alteration in RETN expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2458
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to IER5L and then measure expression of FBXL20. Does this perturbation cause a significant change in FBXL20 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2524
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FAM83A expression is quantified. Does this perturbation result in a significant change in FAM83A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN13 is perturbed and FAM83A expression is quantified. Does this perturbation result in a significant change in FAM83A expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5622
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF18B is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6115
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLAUR. Does this perturbation cause a significant change in PLAUR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLAUR. Does this perturbation cause a significant change in PLAUR expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":734
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in AC016629.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3615
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of TMEM154. Does perturbing KIAA1804 lead to a significant change in TMEM154 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of TMEM154. Does perturbing KIAA1804 lead to a significant change in TMEM154 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4141
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXA1 is perturbed and the expression of CCRL2 is measured. Does this perturbation cause a significant change in CCRL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":340
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Does this perturbation cause a significant change in RP11-369K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Does this perturbation cause a significant change in RP11-369K17.1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5470
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of GYPE. Does perturbing CNNM4 lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNNM4 and examine the expression of GYPE. Does perturbing CNNM4 lead to a significant change in GYPE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4751
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and MSRB1 expression is measured. Determine whether MSRB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and MSRB1 expression is measured. Determine whether MSRB1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2659
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LRP10 expression is observed. Does this perturbation lead to a significant difference in LRP10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXA3 is perturbed and LRP10 expression is observed. Does this perturbation lead to a significant difference in LRP10 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3313
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RP11-320G24.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of OSR2, does the expression profile of RP11-320G24.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5067
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CTD-2527I21.14. Does perturbing IGDCC3 lead to a significant change in CTD-2527I21.14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IGDCC3 and examine the expression of CTD-2527I21.14. Does perturbing IGDCC3 lead to a significant change in CTD-2527I21.14 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4411
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in AKAP13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP2K6 is associated with a significant change in AKAP13 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3985
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOXL2 and then measure expression of SOCS1. Does this perturbation cause a significant change in SOCS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4084
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of HMGA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C3orf72, does the expression profile of HMGA2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3897
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and XX-FW83563B9.5 expression is observed. Does this perturbation lead to a significant difference in XX-FW83563B9.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CLDN6 is perturbed and XX-FW83563B9.5 expression is observed. Does this perturbation lead to a significant difference in XX-FW83563B9.5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3293
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of RPS6KA2. Does this perturbation cause a significant change in RPS6KA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to DLX2 and then measure expression of RPS6KA2. Does this perturbation cause a significant change in RPS6KA2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1604
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Does this perturbation cause a significant change in SSTR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXC13 is perturbed and the expression of SSTR3 is measured. Does this perturbation cause a significant change in SSTR3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3170
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Does this perturbation cause a significant change in ACP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, COL2A1 is perturbed and the expression of ACP5 is measured. Does this perturbation cause a significant change in ACP5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1200
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of CHST15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of TBX2, does the expression profile of CHST15 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2497
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB1 is perturbed and RABGAP1L expression is measured. Determine whether RABGAP1L exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3559
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ATP10D. Does perturbing C19orf26 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ATP10D. Does perturbing C19orf26 lead to a significant change in ATP10D expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2921
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Does this perturbation cause a significant change in HSD17B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CEBPE is perturbed and the expression of HSD17B4 is measured. Does this perturbation cause a significant change in HSD17B4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":140
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of FILIP1L. Does perturbing MAP2K3 lead to a significant change in FILIP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP2K3 and examine the expression of FILIP1L. Does perturbing MAP2K3 lead to a significant change in FILIP1L expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2261
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CSRNP1 is perturbed and ZNF431 expression is observed. Does this perturbation lead to a significant difference in ZNF431 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4673
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and RBM5-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CEBPE is perturbed and RBM5-AS1 expression is observed. Does this perturbation lead to a significant difference in RBM5-AS1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":163
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP3-467K16.2 is measured. Determine whether RP3-467K16.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3716
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of GIPC2. Does perturbing HOXC13 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXC13 and examine the expression of GIPC2. Does perturbing HOXC13 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3151
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-514P8.2. Does perturbing PLK4 lead to a significant change in RP11-514P8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PLK4 and examine the expression of RP11-514P8.2. Does perturbing PLK4 lead to a significant change in RP11-514P8.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3691
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Determine whether RP4-565E6.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ELMSAN1 is perturbed and the expression of RP4-565E6.1 is measured. Determine whether RP4-565E6.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":296
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor C19orf38 expression. Decide whether this perturbation leads to a significant alteration in C19orf38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor C19orf38 expression. Decide whether this perturbation leads to a significant alteration in C19orf38 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4848
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ORAI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of RUNX1T1, does the expression profile of ORAI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1947
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP4K3 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2309
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and APOL6 expression is quantified. Does this perturbation result in a significant change in APOL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL1A1 is perturbed and APOL6 expression is quantified. Does this perturbation result in a significant change in APOL6 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3422
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and TUBB expression is measured. Determine whether TUBB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and TUBB expression is measured. Determine whether TUBB exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2649
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of FLJ12825. Does this perturbation cause a significant change in FLJ12825 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPE and then measure expression of FLJ12825. Does this perturbation cause a significant change in FLJ12825 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":174
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SNCG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of SNCG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1987
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor PRSS57 expression. Decide whether this perturbation leads to a significant alteration in PRSS57 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":428
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TPP1 expression is observed. Does this perturbation lead to a significant difference in TPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which DLX2 is perturbed and TPP1 expression is observed. Does this perturbation lead to a significant difference in TPP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1573
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Does this perturbation cause a significant change in FAM118A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of FAM118A is measured. Does this perturbation cause a significant change in FAM118A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2660
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in RP11-355B11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZNF318 is associated with a significant change in RP11-355B11.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1175
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Does this perturbation cause a significant change in ACSL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of ACSL1 is measured. Does this perturbation cause a significant change in ACSL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2770
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01395 expression is measured. Determine whether LINC01395 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ZBTB10 is perturbed and LINC01395 expression is measured. Determine whether LINC01395 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5599
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01358. Does this perturbation cause a significant change in LINC01358 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of LINC01358. Does this perturbation cause a significant change in LINC01358 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5614
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of KCNQ1-AS1. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of KCNQ1-AS1. Does this perturbation cause a significant change in KCNQ1-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5114
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP11-345P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAPK1, does the expression profile of RP11-345P4.7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2877
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IKZF3 is perturbed and the expression of EMP3 is measured. Does this perturbation cause a significant change in EMP3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3030
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor AFMID expression. Decide whether this perturbation leads to a significant alteration in AFMID expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2968
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CENPE expression is quantified. Does this perturbation result in a significant change in CENPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CDKN1C is perturbed and CENPE expression is quantified. Does this perturbation result in a significant change in CENPE expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6222
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of TNFAIP2. Does this perturbation cause a significant change in TNFAIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CEBPB and then measure expression of TNFAIP2. Does this perturbation cause a significant change in TNFAIP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5204
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-259K5.1. Does this perturbation cause a significant change in RP11-259K5.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of RP11-259K5.1. Does this perturbation cause a significant change in RP11-259K5.1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1244
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Determine whether ICAM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CNNM4 is perturbed and the expression of ICAM4 is measured. Determine whether ICAM4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4746
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, KIF18B is perturbed and ZNF467 expression is measured. Determine whether ZNF467 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6139
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and NKG7 expression is measured. Determine whether NKG7 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4469
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LHX1, does the expression profile of PAQR7 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":997
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of CEBPD. Does perturbing HK2 lead to a significant change in CEBPD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HK2 and examine the expression of CEBPD. Does perturbing HK2 lead to a significant change in CEBPD expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6061
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CD59 expression is measured. Determine whether CD59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1A is perturbed and CD59 expression is measured. Determine whether CD59 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2379
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of MME. Does perturbing CDKN1C lead to a significant change in MME expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1C and examine the expression of MME. Does perturbing CDKN1C lead to a significant change in MME expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6261
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-563J2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-563J2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARRDC3 and monitor RP11-563J2.3 expression. Decide whether this perturbation leads to a significant alteration in RP11-563J2.3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3818
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor EMP3 expression. Decide whether this perturbation leads to a significant alteration in EMP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IKZF3 and monitor EMP3 expression. Decide whether this perturbation leads to a significant alteration in EMP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3038
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and HOGA1 expression is observed. Does this perturbation lead to a significant difference in HOGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and HOGA1 expression is observed. Does this perturbation lead to a significant difference in HOGA1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2863
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Does this perturbation cause a significant change in CCDC136 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of CCDC136 is measured. Does this perturbation cause a significant change in CCDC136 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5030
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIPK1-AS1 expression. Decide whether this perturbation leads to a significant alteration in HIPK1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor HIPK1-AS1 expression. Decide whether this perturbation leads to a significant alteration in HIPK1-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3228
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Does this perturbation cause a significant change in GCM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of GCM2 is measured. Does this perturbation cause a significant change in GCM2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1350
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SKAP1. Does perturbing FEV lead to a significant change in SKAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FEV and examine the expression of SKAP1. Does perturbing FEV lead to a significant change in SKAP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":711
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of SOCS1. Does perturbing FOXL2 lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXL2 and examine the expression of SOCS1. Does perturbing FOXL2 lead to a significant change in SOCS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4081
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of STAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ELMSAN1, does the expression profile of STAC3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":277
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and EWSAT1 expression is quantified. Does this perturbation result in a significant change in EWSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ATL1 is perturbed and EWSAT1 expression is quantified. Does this perturbation result in a significant change in EWSAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5312
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and PPP4R4 expression is observed. Does this perturbation lead to a significant difference in PPP4R4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIF2C is perturbed and PPP4R4 expression is observed. Does this perturbation lead to a significant difference in PPP4R4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4613
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor NCALD expression. Decide whether this perturbation leads to a significant alteration in NCALD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor NCALD expression. Decide whether this perturbation leads to a significant alteration in NCALD expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4838
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SDSL. Does this perturbation cause a significant change in SDSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN1 and then measure expression of SDSL. Does this perturbation cause a significant change in SDSL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2424
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ETS1. Does perturbing KLF1 lead to a significant change in ETS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KLF1 and examine the expression of ETS1. Does perturbing KLF1 lead to a significant change in ETS1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":581
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and S100A13 expression is quantified. Does this perturbation result in a significant change in S100A13 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1822
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Determine whether MARCKS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZC3HAV1 is perturbed and the expression of MARCKS is measured. Determine whether MARCKS shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4996
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ACSL1. Does this perturbation cause a significant change in ACSL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FOSB and then measure expression of ACSL1. Does this perturbation cause a significant change in ACSL1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2774
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Determine whether RP11-6D1.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K6 is perturbed and the expression of RP11-6D1.3 is measured. Determine whether RP11-6D1.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4016
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in KRT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOSB is associated with a significant change in KRT7 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2795
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor DCAF13 expression. Decide whether this perturbation leads to a significant alteration in DCAF13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB1 and monitor DCAF13 expression. Decide whether this perturbation leads to a significant alteration in DCAF13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3548
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HNF4A, does the expression profile of AP1S2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4267
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and ZMAT3 expression is observed. Does this perturbation lead to a significant difference in ZMAT3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5133
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SLC20A1 expression is quantified. Does this perturbation result in a significant change in SLC20A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN1 is perturbed and SLC20A1 expression is quantified. Does this perturbation result in a significant change in SLC20A1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2402
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP7D1, does the expression profile of TNNI3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2707
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZBTB10 and monitor CSF3R expression. Decide whether this perturbation leads to a significant alteration in CSF3R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5578
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in AC006262.5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4575
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor RP11-91A18.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-91A18.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TP73 and monitor RP11-91A18.4 expression. Decide whether this perturbation leads to a significant alteration in RP11-91A18.4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2698
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TPP1 expression is quantified. Does this perturbation result in a significant change in TPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, DLX2 is perturbed and TPP1 expression is quantified. Does this perturbation result in a significant change in TPP1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1572
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of TMEM35. Does this perturbation cause a significant change in TMEM35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of TMEM35. Does this perturbation cause a significant change in TMEM35 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5014
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is measured. Determine whether RP11-537H15.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAP2K3 is perturbed and RP11-537H15.3 expression is measured. Determine whether RP11-537H15.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2279
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, C3orf72 is perturbed and the expression of MFSD2A is measured. Does this perturbation cause a significant change in MFSD2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3870
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in WDR88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in WDR88 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4725
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ZNF610. Does perturbing PTPN1 lead to a significant change in ZNF610 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN1 and examine the expression of ZNF610. Does perturbing PTPN1 lead to a significant change in ZNF610 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2431
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CRYM. Does perturbing POU3F2 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb POU3F2 and examine the expression of CRYM. Does perturbing POU3F2 lead to a significant change in CRYM expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2061
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RP11-308D13.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBL, does the expression profile of RP11-308D13.3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":767
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Does this perturbation cause a significant change in ATG2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PRTG is perturbed and the expression of ATG2A is measured. Does this perturbation cause a significant change in ATG2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3630
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and MTURN expression is quantified. Does this perturbation result in a significant change in MTURN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, RHOXF2BB is perturbed and MTURN expression is quantified. Does this perturbation result in a significant change in MTURN expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1882
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb DLX2 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1588
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor RNF182 expression. Decide whether this perturbation leads to a significant alteration in RNF182 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LYL1 and monitor RNF182 expression. Decide whether this perturbation leads to a significant alteration in RNF182 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3958
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and APOL6 expression is observed. Does this perturbation lead to a significant difference in APOL6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which COL1A1 is perturbed and APOL6 expression is observed. Does this perturbation lead to a significant difference in APOL6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3423
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor AGXT expression. Decide whether this perturbation leads to a significant alteration in AGXT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SLC4A1 and monitor AGXT expression. Decide whether this perturbation leads to a significant alteration in AGXT expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1058
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ISL2, does the expression profile of GIPC2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4487
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and ESAM expression is observed. Does this perturbation lead to a significant difference in ESAM expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4153
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of VMP1. Does perturbing HOXA13 lead to a significant change in VMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb HOXA13 and examine the expression of VMP1. Does perturbing HOXA13 lead to a significant change in VMP1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5861
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of LST1. Does perturbing IRF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IRF1 and examine the expression of LST1. Does perturbing IRF1 lead to a significant change in LST1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2941
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in ZNF467 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":875
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXF1 is associated with a significant change in ALAS2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3505
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KMT2A is perturbed and FABP5 expression is quantified. Does this perturbation result in a significant change in FABP5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4322
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of CNN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ARID1A, does the expression profile of CNN2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4707
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB10 is associated with a significant change in CSF3R expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5575
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Does this perturbation cause a significant change in SOCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of SOCS2 is measured. Does this perturbation cause a significant change in SOCS2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":690
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and APOBR expression is quantified. Does this perturbation result in a significant change in APOBR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, STIL is perturbed and APOBR expression is quantified. Does this perturbation result in a significant change in APOBR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5172
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ETS2 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":794
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC6A9 is associated with a significant change in BTG2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1465
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in UBASH3B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1405
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ARPC3 expression is measured. Determine whether ARPC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and ARPC3 expression is measured. Determine whether ARPC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":849
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ZBTB25 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1275
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of MYL4. Does this perturbation cause a significant change in MYL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZBTB10 and then measure expression of MYL4. Does this perturbation cause a significant change in MYL4 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5564
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in REEP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of S1PR2 is associated with a significant change in REEP6 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2005
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in SH3RF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CKS1B is associated with a significant change in SH3RF2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3235
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM83F expression is observed. Does this perturbation lead to a significant difference in FAM83F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TP73 is perturbed and FAM83F expression is observed. Does this perturbation lead to a significant difference in FAM83F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2683
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of PXK. Does perturbing CELF2 lead to a significant change in PXK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of PXK. Does perturbing CELF2 lead to a significant change in PXK expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2171
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of HEMGN indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3917
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and HOGA1 expression is measured. Determine whether HOGA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MAPK1 is perturbed and HOGA1 expression is measured. Determine whether HOGA1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2869
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of CAPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NCL, does the expression profile of CAPG indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4877
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ID3. Does perturbing FOXF1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of ID3. Does perturbing FOXF1 lead to a significant change in ID3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3481
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor TCAF2 expression. Decide whether this perturbation leads to a significant alteration in TCAF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IRF1 and monitor TCAF2 expression. Decide whether this perturbation leads to a significant alteration in TCAF2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2978
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Does this perturbation cause a significant change in RP11-91A18.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, TP73 is perturbed and the expression of RP11-91A18.4 is measured. Does this perturbation cause a significant change in RP11-91A18.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2690
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Determine whether RP11-369K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TGFBR2 is perturbed and the expression of RP11-369K17.1 is measured. Determine whether RP11-369K17.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5476
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor ZC3HAV1 expression. Decide whether this perturbation leads to a significant alteration in ZC3HAV1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4978
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of FAM178B. Does perturbing PTPN12 lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN12 and examine the expression of FAM178B. Does perturbing PTPN12 lead to a significant change in FAM178B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2601
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN12 is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2583
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Does this perturbation cause a significant change in SLC2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IER5L is perturbed and the expression of SLC2A3 is measured. Does this perturbation cause a significant change in SLC2A3 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2530
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Determine whether PGA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of PGA4 is measured. Determine whether PGA4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6036
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in AC144568.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KLF1 is associated with a significant change in AC144568.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":595
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and TPH2 expression is quantified. Does this perturbation result in a significant change in TPH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and TPH2 expression is quantified. Does this perturbation result in a significant change in TPH2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3412
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Determine whether LINC01338 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, OSR2 is perturbed and the expression of LINC01338 is measured. Determine whether LINC01338 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5076
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of NCKAP1L is measured. Determine whether NCKAP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3086
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of PDE1B. Does this perturbation cause a significant change in PDE1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of PDE1B. Does this perturbation cause a significant change in PDE1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":34
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Determine whether MMP19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX3 is perturbed and the expression of MMP19 is measured. Determine whether MMP19 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":946
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Determine whether FAM49A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MEIS1 is perturbed and the expression of FAM49A is measured. Determine whether FAM49A shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":476
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and SOCS3 expression is observed. Does this perturbation lead to a significant difference in SOCS3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2843
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of UBE2H. Does perturbing JUN lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb JUN and examine the expression of UBE2H. Does perturbing JUN lead to a significant change in UBE2H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5511
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in PSMB8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAML2 is associated with a significant change in PSMB8 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":105
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and RP11-445F12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-445F12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and RP11-445F12.1 expression is observed. Does this perturbation lead to a significant difference in RP11-445F12.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":603
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CREB3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in CREB3L2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5995
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAML2 is perturbed and the expression of ID1 is measured. Determine whether ID1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":76
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HHEX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SAMD1 is associated with a significant change in HHEX expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3385
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor RAB5B expression. Decide whether this perturbation leads to a significant alteration in RAB5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor RAB5B expression. Decide whether this perturbation leads to a significant alteration in RAB5B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":688
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ABCA6. Does this perturbation cause a significant change in ABCA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIAA1804 and then measure expression of ABCA6. Does this perturbation cause a significant change in ABCA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4174
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of HSD17B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of HSD17B4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":147
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is measured. Determine whether RP11-445F12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and RP11-445F12.1 expression is measured. Determine whether RP11-445F12.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":609
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of CFH. Does this perturbation cause a significant change in CFH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5444
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of STRA6. Does this perturbation cause a significant change in STRA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BAK1 and then measure expression of STRA6. Does this perturbation cause a significant change in STRA6 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":654
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-328J14.1 expression is measured. Determine whether RP11-328J14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, IER5L is perturbed and RP11-328J14.1 expression is measured. Determine whether RP11-328J14.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2579
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of XX-FW83563B9.5. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of XX-FW83563B9.5. Does this perturbation cause a significant change in XX-FW83563B9.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3294
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of MARCKS. Does perturbing ZC3HAV1 lead to a significant change in MARCKS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZC3HAV1 and examine the expression of MARCKS. Does perturbing ZC3HAV1 lead to a significant change in MARCKS expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4991
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of FAM46C. Does perturbing C19orf26 lead to a significant change in FAM46C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of FAM46C. Does perturbing C19orf26 lead to a significant change in FAM46C expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2891
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and NKG7 expression is quantified. Does this perturbation result in a significant change in NKG7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2592
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C6orf1 expression is measured. Determine whether C6orf1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C6orf1 expression is measured. Determine whether C6orf1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1879
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and C1orf162 expression is quantified. Does this perturbation result in a significant change in C1orf162 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXF1 is perturbed and C1orf162 expression is quantified. Does this perturbation result in a significant change in C1orf162 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3532
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOSB is perturbed and RUNX1 expression is quantified. Does this perturbation result in a significant change in RUNX1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2782
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DLX2 is perturbed and the expression of HEMGN is measured. Does this perturbation cause a significant change in HEMGN expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1560
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to JUN and then measure expression of AFMID. Does this perturbation cause a significant change in AFMID expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5504
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LRP10 expression is quantified. Does this perturbation result in a significant change in LRP10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXA3 is perturbed and LRP10 expression is quantified. Does this perturbation result in a significant change in LRP10 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3312
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN12 is perturbed and FAM178B expression is measured. Determine whether FAM178B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2609
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is measured. Determine whether RP11-563J2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is measured. Determine whether RP11-563J2.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3819
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor CAPG expression. Decide whether this perturbation leads to a significant alteration in CAPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor CAPG expression. Decide whether this perturbation leads to a significant alteration in CAPG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4878
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Determine whether CYP1B1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of CYP1B1-AS1 is measured. Determine whether CYP1B1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4316
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and RP11-38J22.3 expression is measured. Determine whether RP11-38J22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, HK2 is perturbed and RP11-38J22.3 expression is measured. Determine whether RP11-38J22.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6079
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and FABP3 expression is measured. Determine whether FABP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and FABP3 expression is measured. Determine whether FABP3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3729
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and TMEM88 expression is measured. Determine whether TMEM88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and TMEM88 expression is measured. Determine whether TMEM88 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5189
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BAK1 is perturbed and LHX1 expression is measured. Determine whether LHX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":619
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of AC078941.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of S1PR2, does the expression profile of AC078941.1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2017
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARID1A is associated with a significant change in TXNIP expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4695
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of RLN3. Does this perturbation cause a significant change in RLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ZC3HAV1 and then measure expression of RLN3. Does this perturbation cause a significant change in RLN3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5004
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAML2, does the expression profile of ID1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":77
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of PXK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CELF2, does the expression profile of PXK indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2177
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SKAP1 expression is measured. Determine whether SKAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FEV is perturbed and SKAP1 expression is measured. Determine whether SKAP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":719
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of PLEK. Does this perturbation cause a significant change in PLEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of PLEK. Does this perturbation cause a significant change in PLEK expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5094
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of CRYAB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of MAP4K5, does the expression profile of CRYAB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1347
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Does this perturbation cause a significant change in SIGLEC15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RUNX1T1 is perturbed and the expression of SIGLEC15 is measured. Does this perturbation cause a significant change in SIGLEC15 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1960
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and RABGAP1L expression is quantified. Does this perturbation result in a significant change in RABGAP1L expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":482
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C6orf1 expression is observed. Does this perturbation lead to a significant difference in C6orf1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RHOXF2BB is perturbed and C6orf1 expression is observed. Does this perturbation lead to a significant difference in C6orf1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1873
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of FEZ1 is measured. Does this perturbation cause a significant change in FEZ1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4770
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in TNNI3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1725
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Does this perturbation cause a significant change in RABAC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, STIL is perturbed and the expression of RABAC1 is measured. Does this perturbation cause a significant change in RABAC1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5140
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Does this perturbation cause a significant change in ABCA13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, POU3F2 is perturbed and the expression of ABCA13 is measured. Does this perturbation cause a significant change in ABCA13 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2090
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor RP11-369K17.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-369K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TGFBR2 and monitor RP11-369K17.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-369K17.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5478
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB1 is perturbed and CD24 expression is observed. Does this perturbation lead to a significant difference in CD24 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3573
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor MSX1 expression. Decide whether this perturbation leads to a significant alteration in MSX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor MSX1 expression. Decide whether this perturbation leads to a significant alteration in MSX1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4038
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Does this perturbation cause a significant change in LRRC74B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CSRNP1 is perturbed and the expression of LRRC74B is measured. Does this perturbation cause a significant change in LRRC74B expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4650
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PSMB9. Does perturbing ATL1 lead to a significant change in PSMB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of PSMB9. Does perturbing ATL1 lead to a significant change in PSMB9 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5281
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CRAT37 expression is measured. Determine whether CRAT37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, EGR1 is perturbed and CRAT37 expression is measured. Determine whether CRAT37 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6199
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and RP11-505P4.6 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which RREB1 is perturbed and RP11-505P4.6 expression is observed. Does this perturbation lead to a significant difference in RP11-505P4.6 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1133
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAP4K5 is perturbed and FEV expression is quantified. Does this perturbation result in a significant change in FEV expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1322
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Does this perturbation cause a significant change in MCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of MCC is measured. Does this perturbation cause a significant change in MCC expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3510
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRTG is associated with a significant change in ACE expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3655
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOXF1 is perturbed and ALAS2 expression is observed. Does this perturbation lead to a significant difference in ALAS2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3503
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Does this perturbation cause a significant change in CRYAB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K5 is perturbed and the expression of CRYAB is measured. Does this perturbation cause a significant change in CRYAB expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1340
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and CLU expression is measured. Determine whether CLU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TSC22D1 is perturbed and CLU expression is measured. Determine whether CLU exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":19
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ZNF467. Does perturbing KIF18B lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of ZNF467. Does perturbing KIF18B lead to a significant change in ZNF467 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6131
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb UBASH3A and monitor AC074289.1 expression. Decide whether this perturbation leads to a significant alteration in AC074289.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4858
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C8orf22 expression is measured. Determine whether C8orf22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RHOXF2BB is perturbed and C8orf22 expression is measured. Determine whether C8orf22 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1899
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and RABAC1 expression is observed. Does this perturbation lead to a significant difference in RABAC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which STIL is perturbed and RABAC1 expression is observed. Does this perturbation lead to a significant difference in RABAC1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5143
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ANXA2R expression. Decide whether this perturbation leads to a significant alteration in ANXA2R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HOXA13 and monitor ANXA2R expression. Decide whether this perturbation leads to a significant alteration in ANXA2R expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5878
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor RIMBP3C expression. Decide whether this perturbation leads to a significant alteration in RIMBP3C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor RIMBP3C expression. Decide whether this perturbation leads to a significant alteration in RIMBP3C expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3288
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, KLF1 is perturbed and LST1 expression is quantified. Does this perturbation result in a significant change in LST1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":552
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of PNMT is measured. Determine whether PNMT shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3666
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor AKAP13 expression. Decide whether this perturbation leads to a significant alteration in AKAP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor AKAP13 expression. Decide whether this perturbation leads to a significant alteration in AKAP13 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3988
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TPP1 expression is measured. Determine whether TPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DLX2 is perturbed and TPP1 expression is measured. Determine whether TPP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1579
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RREB1 is associated with a significant change in CTSL expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1095
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor CLTA expression. Decide whether this perturbation leads to a significant alteration in CLTA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MAP2K6 and monitor CLTA expression. Decide whether this perturbation leads to a significant alteration in CLTA expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3998
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP2K3 and then measure expression of PYROXD2. Does this perturbation cause a significant change in PYROXD2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2224
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of RBM5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CEBPE, does the expression profile of RBM5-AS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":167
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of GIPC2. Does this perturbation cause a significant change in GIPC2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3154
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, IER5L is perturbed and the expression of SKAP2 is measured. Determine whether SKAP2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2546
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and MYLIP expression is measured. Determine whether MYLIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and MYLIP expression is measured. Determine whether MYLIP exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1239
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SNAI1 and then measure expression of ZNF431. Does this perturbation cause a significant change in ZNF431 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5834
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3B is associated with a significant change in SOCS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1395
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ZNF610 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in ZNF610 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2435
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in SOX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1A is associated with a significant change in SOX4 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2355
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and S100A4 expression is measured. Determine whether S100A4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC4A1 is perturbed and S100A4 expression is measured. Determine whether S100A4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1049
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Determine whether SPTAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CELF2 is perturbed and the expression of SPTAN1 is measured. Determine whether SPTAN1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2166
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of TSC22D4 is measured. Does this perturbation cause a significant change in TSC22D4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":190
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Does this perturbation cause a significant change in RP1-261G23.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of RP1-261G23.7 is measured. Does this perturbation cause a significant change in RP1-261G23.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1900
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ETS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KLF1, does the expression profile of ETS1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":587
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, ZC3HAV1 is perturbed and the expression of AC006262.5 is measured. Does this perturbation cause a significant change in AC006262.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4980
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Does this perturbation cause a significant change in CDK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, IGDCC3 is perturbed and the expression of CDK1 is measured. Does this perturbation cause a significant change in CDK1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4400
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of AMHR2. Does perturbing KIF18B lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF18B and examine the expression of AMHR2. Does perturbing KIF18B lead to a significant change in AMHR2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6101
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and SPANXD expression is observed. Does this perturbation lead to a significant difference in SPANXD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which KIAA1804 is perturbed and SPANXD expression is observed. Does this perturbation lead to a significant difference in SPANXD expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4193
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LRRC74B. Does perturbing CSRNP1 lead to a significant change in LRRC74B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CSRNP1 and examine the expression of LRRC74B. Does perturbing CSRNP1 lead to a significant change in LRRC74B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4651
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and NUDC expression is quantified. Does this perturbation result in a significant change in NUDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CNN1 is perturbed and NUDC expression is quantified. Does this perturbation result in a significant change in NUDC expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2152
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MS4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of LYL1, does the expression profile of MS4A2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3937
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Does this perturbation cause a significant change in ATP8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of ATP8A1 is measured. Does this perturbation cause a significant change in ATP8A1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3520
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of NUMB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of NUMB indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3267
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Determine whether AC007556.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of AC007556.3 is measured. Determine whether AC007556.3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":826
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLAUR expression is quantified. Does this perturbation result in a significant change in PLAUR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CBL is perturbed and PLAUR expression is quantified. Does this perturbation result in a significant change in PLAUR expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":732
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3509
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of GIPC2. Does perturbing ISL2 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ISL2 and examine the expression of GIPC2. Does perturbing ISL2 lead to a significant change in GIPC2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4481
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of LTC4S. Does this perturbation cause a significant change in LTC4S expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRTG and then measure expression of LTC4S. Does this perturbation cause a significant change in LTC4S expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3644
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is measured. Determine whether CTC-492K19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, RREB1 is perturbed and CTC-492K19.4 expression is measured. Determine whether CTC-492K19.4 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1129
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Does this perturbation cause a significant change in C6orf1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Does this perturbation cause a significant change in C6orf1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1870
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MIDN and monitor TLN1 expression. Decide whether this perturbation leads to a significant alteration in TLN1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1528
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of TMEM154 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIAA1804, does the expression profile of TMEM154 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4147
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of RP3-467K16.2 is measured. Does this perturbation cause a significant change in RP3-467K16.2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1470
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Does this perturbation cause a significant change in LGALS12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, DUSP9 is perturbed and the expression of LGALS12 is measured. Does this perturbation cause a significant change in LGALS12 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":180
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Does this perturbation cause a significant change in PTPRS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FEV is perturbed and the expression of PTPRS is measured. Does this perturbation cause a significant change in PTPRS expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":660
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ABCB11 expression is measured. Determine whether ABCB11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CBFA2T3 is perturbed and ABCB11 expression is measured. Determine whether ABCB11 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1669
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1C and then measure expression of CDC45. Does this perturbation cause a significant change in CDC45 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6244
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor XX-FW83563B9.5 expression. Decide whether this perturbation leads to a significant alteration in XX-FW83563B9.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CLDN6 and monitor XX-FW83563B9.5 expression. Decide whether this perturbation leads to a significant alteration in XX-FW83563B9.5 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3298
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MIDN and then measure expression of TLN1. Does this perturbation cause a significant change in TLN1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1524
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Does this perturbation cause a significant change in AC004540.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXL2 is perturbed and the expression of AC004540.4 is measured. Does this perturbation cause a significant change in AC004540.4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4120
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of UNC5B. Does this perturbation cause a significant change in UNC5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CLDN6 and then measure expression of UNC5B. Does this perturbation cause a significant change in UNC5B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3254
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and RP1-34B20.21 expression is quantified. Does this perturbation result in a significant change in RP1-34B20.21 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTC-492K19.4. Does perturbing RREB1 lead to a significant change in CTC-492K19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of CTC-492K19.4. Does perturbing RREB1 lead to a significant change in CTC-492K19.4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1121
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ZNF85 expression is quantified. Does this perturbation result in a significant change in ZNF85 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, GLB1L2 is perturbed and ZNF85 expression is quantified. Does this perturbation result in a significant change in ZNF85 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":512
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ZNF85 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of GLB1L2, does the expression profile of ZNF85 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":517
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, HES7 is perturbed and TNNI3 expression is quantified. Does this perturbation result in a significant change in TNNI3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1722
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, POU3F2 is perturbed and the expression of BTG2 is measured. Determine whether BTG2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2046
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SKAP2. Does perturbing IER5L lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb IER5L and examine the expression of SKAP2. Does perturbing IER5L lead to a significant change in SKAP2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2541
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of FABP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BPGM, does the expression profile of FABP3 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3727
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ACP5. Does this perturbation cause a significant change in ACP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to COL2A1 and then measure expression of ACP5. Does this perturbation cause a significant change in ACP5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1204
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in IFIT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PRDM1 is associated with a significant change in IFIT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6025
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Determine whether RETN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of RETN is measured. Determine whether RETN shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2456
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C8orf22. Does this perturbation cause a significant change in C8orf22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to RHOXF2BB and then measure expression of C8orf22. Does this perturbation cause a significant change in C8orf22 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1894
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of CRABP2. Does this perturbation cause a significant change in CRABP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to ELMSAN1 and then measure expression of CRABP2. Does this perturbation cause a significant change in CRABP2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":284
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and HCAR2 expression is measured. Determine whether HCAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, STIL is perturbed and HCAR2 expression is measured. Determine whether HCAR2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5199
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TFAP2A-AS1. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KMT2A and then measure expression of TFAP2A-AS1. Does this perturbation cause a significant change in TFAP2A-AS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4364
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and TTC9B expression is measured. Determine whether TTC9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ISL2 is perturbed and TTC9B expression is measured. Determine whether TTC9B exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4499
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, FOXF1 is perturbed and FOXF1 expression is measured. Determine whether FOXF1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3499
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Does this perturbation cause a significant change in DYNLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOSB is perturbed and the expression of DYNLL1 is measured. Does this perturbation cause a significant change in DYNLL1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2810
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Does this perturbation cause a significant change in MS4A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, LYL1 is perturbed and the expression of MS4A2 is measured. Does this perturbation cause a significant change in MS4A2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3930
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which IKZF3 is perturbed and BST2 expression is observed. Does this perturbation lead to a significant difference in BST2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3013
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Determine whether ATP10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, C19orf26 is perturbed and the expression of ATP10D is measured. Determine whether ATP10D shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2926
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXL2 is associated with a significant change in COLGALT2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4095
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in UBASH3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4825
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and TOX expression is observed. Does this perturbation lead to a significant difference in TOX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP4K5 is perturbed and TOX expression is observed. Does this perturbation lead to a significant difference in TOX expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1363
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor MACF1 expression. Decide whether this perturbation leads to a significant alteration in MACF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor MACF1 expression. Decide whether this perturbation leads to a significant alteration in MACF1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4738
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of BLVRB. Does perturbing EGR1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb EGR1 and examine the expression of BLVRB. Does perturbing EGR1 lead to a significant change in BLVRB expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6171
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in RP11-635N19.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAP4K5 is associated with a significant change in RP11-635N19.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1375
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CSRNP1 is associated with a significant change in LGALS1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4635
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SET is perturbed and the expression of CTD-2031P19.5 is measured. Does this perturbation cause a significant change in CTD-2031P19.5 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":880
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAML2 is perturbed and CD52 expression is observed. Does this perturbation lead to a significant difference in CD52 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":83
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of C1orf162. Does perturbing FOXF1 lead to a significant change in C1orf162 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXF1 and examine the expression of C1orf162. Does perturbing FOXF1 lead to a significant change in C1orf162 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3531
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP3-510H16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ARRDC3 is associated with a significant change in RP3-510H16.3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3835
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, KLF1 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":566
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Determine whether TAS1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of TAS1R1 is measured. Determine whether TAS1R1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":706
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and LTC4S expression is quantified. Does this perturbation result in a significant change in LTC4S expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PRTG is perturbed and LTC4S expression is quantified. Does this perturbation result in a significant change in LTC4S expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3642
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb JUN and monitor UBE2H expression. Decide whether this perturbation leads to a significant alteration in UBE2H expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5518
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TMEM55A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of TMEM55A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4607
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor CTA-384D8.34 expression. Decide whether this perturbation leads to a significant alteration in CTA-384D8.34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BAK1 and monitor CTA-384D8.34 expression. Decide whether this perturbation leads to a significant alteration in CTA-384D8.34 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":648
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SDSL expression is measured. Determine whether SDSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, PTPN1 is perturbed and SDSL expression is measured. Determine whether SDSL exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2429
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TUBB2B. Does perturbing DLX2 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb DLX2 and examine the expression of TUBB2B. Does perturbing DLX2 lead to a significant change in TUBB2B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1581
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RP11-83A24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-83A24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb GLB1L2 and monitor RP11-83A24.2 expression. Decide whether this perturbation leads to a significant alteration in RP11-83A24.2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":528
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TSC22D1 is perturbed and RP1-34B20.21 expression is observed. Does this perturbation lead to a significant difference in RP1-34B20.21 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB1, does the expression profile of RABGAP1L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3557
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Determine whether RP11-290K4.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PLK4 is perturbed and the expression of RP11-290K4.2 is measured. Determine whether RP11-290K4.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3706
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SKAP1 expression. Decide whether this perturbation leads to a significant alteration in SKAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FEV and monitor SKAP1 expression. Decide whether this perturbation leads to a significant alteration in SKAP1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":718
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor RP11-195C7.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195C7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb HES7 and monitor RP11-195C7.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-195C7.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1738
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SKAP1. Does this perturbation cause a significant change in SKAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to FEV and then measure expression of SKAP1. Does this perturbation cause a significant change in SKAP1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":714
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SPI1 is perturbed and TYROBP expression is observed. Does this perturbation lead to a significant difference in TYROBP expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5083
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SLC6A9 is perturbed and the expression of BTG2 is measured. Does this perturbation cause a significant change in BTG2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1460
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CCS expression. Decide whether this perturbation leads to a significant alteration in CCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor CCS expression. Decide whether this perturbation leads to a significant alteration in CCS expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":138
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of FCGR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of ZBTB10, does the expression profile of FCGR3A indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5607
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and CHST15 expression is observed. Does this perturbation lead to a significant difference in CHST15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and CHST15 expression is observed. Does this perturbation lead to a significant difference in CHST15 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2493
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of MCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of FOXF1, does the expression profile of MCC indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3517
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in TAS2R9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SET is associated with a significant change in TAS2R9 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":895
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor FABP3 expression. Decide whether this perturbation leads to a significant alteration in FABP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor FABP3 expression. Decide whether this perturbation leads to a significant alteration in FABP3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3728
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and PKIG expression is measured. Determine whether PKIG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, DUSP9 is perturbed and PKIG expression is measured. Determine whether PKIG exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":209
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BAK1, does the expression profile of BAK1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":627
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CDKN1A is perturbed and DST expression is observed. Does this perturbation lead to a significant difference in DST expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2343
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in BMP2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MIDN is associated with a significant change in BMP2K expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1505
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and MAOB expression is quantified. Does this perturbation result in a significant change in MAOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SLC6A9 is perturbed and MAOB expression is quantified. Does this perturbation result in a significant change in MAOB expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1492
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and MYO1F expression is observed. Does this perturbation lead to a significant difference in MYO1F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MIDN is perturbed and MYO1F expression is observed. Does this perturbation lead to a significant difference in MYO1F expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1513
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MBP expression. Decide whether this perturbation leads to a significant alteration in MBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MBP expression. Decide whether this perturbation leads to a significant alteration in MBP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1008
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of PRSS57 is measured. Does this perturbation cause a significant change in PRSS57 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4160
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor GRAP2 expression. Decide whether this perturbation leads to a significant alteration in GRAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb FOXA1 and monitor GRAP2 expression. Decide whether this perturbation leads to a significant alteration in GRAP2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":318
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCL2L11 is perturbed and RP3-467K16.2 expression is observed. Does this perturbation lead to a significant difference in RP3-467K16.2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4953
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SNAI1 is perturbed and HERPUD1 expression is quantified. Does this perturbation result in a significant change in HERPUD1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5822
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of LHX1 is associated with a significant change in CST3 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":975
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Determine whether AC145110.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXB9 is perturbed and the expression of AC145110.1 is measured. Determine whether AC145110.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3116
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, CKS1B is perturbed and ZC3HAV1 expression is quantified. Does this perturbation result in a significant change in ZC3HAV1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3192
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HES7 is associated with a significant change in C17orf64 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1715
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SPI1 and then measure expression of TYROBP. Does this perturbation cause a significant change in TYROBP expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5084
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Determine whether ATF6B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NIT1 is perturbed and the expression of ATF6B is measured. Determine whether ATF6B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5326
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RGPD5 expression is observed. Does this perturbation lead to a significant difference in RGPD5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which CITED1 is perturbed and RGPD5 expression is observed. Does this perturbation lead to a significant difference in RGPD5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5963
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA5 expression is observed. Does this perturbation lead to a significant difference in ANXA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAPK1 is perturbed and ANXA5 expression is observed. Does this perturbation lead to a significant difference in ANXA5 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2853
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TSC22D1 is perturbed and TRIM22 expression is quantified. Does this perturbation result in a significant change in TRIM22 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":52
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, PTPN9 is perturbed and the expression of FBXL20 is measured. Does this perturbation cause a significant change in FBXL20 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5760
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and GIPR expression is measured. Determine whether GIPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, NIT1 is perturbed and GIPR expression is measured. Determine whether GIPR exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5359
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which SLC6A9 is perturbed and RCSD1 expression is observed. Does this perturbation lead to a significant difference in RCSD1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1443
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of RP11-76E17.2. Does perturbing FOXA3 lead to a significant change in RP11-76E17.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA3 and examine the expression of RP11-76E17.2. Does perturbing FOXA3 lead to a significant change in RP11-76E17.2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3341
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Determine whether FAM19A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of FAM19A2 is measured. Determine whether FAM19A2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3366
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TMSB4X is perturbed and TM6SF2 expression is measured. Determine whether TM6SF2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4549
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor KRTAP9-9 expression. Decide whether this perturbation leads to a significant alteration in KRTAP9-9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ATL1 and monitor KRTAP9-9 expression. Decide whether this perturbation leads to a significant alteration in KRTAP9-9 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5298
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Does this perturbation cause a significant change in DPYSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, SNAI1 is perturbed and the expression of DPYSL2 is measured. Does this perturbation cause a significant change in DPYSL2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5800
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AC034228.4 expression is observed. Does this perturbation lead to a significant difference in AC034228.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HNF4A is perturbed and AC034228.4 expression is observed. Does this perturbation lead to a significant difference in AC034228.4 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4293
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Determine whether LEFTY2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, BCL2L11 is perturbed and the expression of LEFTY2 is measured. Determine whether LEFTY2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4946
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Determine whether FAM83F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TP73 is perturbed and the expression of FAM83F is measured. Determine whether FAM83F shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2686
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CNNM4 is perturbed and the expression of PHLDA2 is measured. Does this perturbation cause a significant change in PHLDA2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4760
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA2. Does perturbing MAPK1 lead to a significant change in ANXA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAPK1 and examine the expression of ANXA2. Does perturbing MAPK1 lead to a significant change in ANXA2 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2831
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and XK expression is quantified. Does this perturbation result in a significant change in XK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, PTPN12 is perturbed and XK expression is quantified. Does this perturbation result in a significant change in XK expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2622
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CTD-3131K8.3. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP7D1 and then measure expression of CTD-3131K8.3. Does this perturbation cause a significant change in CTD-3131K8.3 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2754
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to KIF18B and then measure expression of AMHR2. Does this perturbation cause a significant change in AMHR2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6104
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ARL6IP1 expression is measured. Determine whether ARL6IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and ARL6IP1 expression is measured. Determine whether ARL6IP1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2939
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of AGXT. Does perturbing SLC4A1 lead to a significant change in AGXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SLC4A1 and examine the expression of AGXT. Does perturbing SLC4A1 lead to a significant change in AGXT expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1051
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of AMPH. Does this perturbation cause a significant change in AMPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PRDM1 and then measure expression of AMPH. Does this perturbation cause a significant change in AMPH expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6014
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and CTSS expression is quantified. Does this perturbation result in a significant change in CTSS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, S1PR2 is perturbed and CTSS expression is quantified. Does this perturbation result in a significant change in CTSS expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2022
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in AC064834.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in AC064834.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2445
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Determine whether MYOZ3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, LYL1 is perturbed and the expression of MYOZ3 is measured. Determine whether MYOZ3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3946
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SNCG expression. Decide whether this perturbation leads to a significant alteration in SNCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb S1PR2 and monitor SNCG expression. Decide whether this perturbation leads to a significant alteration in SNCG expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1988
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MS4A3 expression. Decide whether this perturbation leads to a significant alteration in MS4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb LHX1 and monitor MS4A3 expression. Decide whether this perturbation leads to a significant alteration in MS4A3 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":988
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and WDR88 expression is quantified. Does this perturbation result in a significant change in WDR88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARID1A is perturbed and WDR88 expression is quantified. Does this perturbation result in a significant change in WDR88 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4722
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Does this perturbation cause a significant change in ANXA2R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, HOXA13 is perturbed and the expression of ANXA2R is measured. Does this perturbation cause a significant change in ANXA2R expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5870
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in RAB5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in RAB5B expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":685
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RP11-285F7.2 expression is quantified. Does this perturbation result in a significant change in RP11-285F7.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, NCL is perturbed and RP11-285F7.2 expression is quantified. Does this perturbation result in a significant change in RP11-285F7.2 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4902
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor DRC1 expression. Decide whether this perturbation leads to a significant alteration in DRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor DRC1 expression. Decide whether this perturbation leads to a significant alteration in DRC1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5668
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and DYNLL1 expression is observed. Does this perturbation lead to a significant difference in DYNLL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FOSB is perturbed and DYNLL1 expression is observed. Does this perturbation lead to a significant difference in DYNLL1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2813
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor FCER1G expression. Decide whether this perturbation leads to a significant alteration in FCER1G expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5648
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of PPP4R4. Does perturbing KIF2C lead to a significant change in PPP4R4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIF2C and examine the expression of PPP4R4. Does perturbing KIF2C lead to a significant change in PPP4R4 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4611
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and CTNNB1 expression is observed. Does this perturbation lead to a significant difference in CTNNB1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":503
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HOXC13 is perturbed and NUCB2 expression is observed. Does this perturbation lead to a significant difference in NUCB2 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3133
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CSRNP1 is perturbed and LGALS1 expression is measured. Determine whether LGALS1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4639
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PTPN13 and monitor BST2 expression. Decide whether this perturbation leads to a significant alteration in BST2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5638
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of INHBE. Does perturbing PTPN9 lead to a significant change in INHBE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb PTPN9 and examine the expression of INHBE. Does perturbing PTPN9 lead to a significant change in INHBE expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5781
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ZBTB10 is perturbed and the expression of ANTXR2 is measured. Determine whether ANTXR2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5586
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Determine whether HIPK1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CKS1B is perturbed and the expression of HIPK1-AS1 is measured. Determine whether HIPK1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3226
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Determine whether RP11-195C7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of RP11-195C7.1 is measured. Determine whether RP11-195C7.1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1736
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Determine whether YPEL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN9 is perturbed and the expression of YPEL3 is measured. Determine whether YPEL3 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5756
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ARL6IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of C19orf26, does the expression profile of ARL6IP1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2937
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BAK1 is perturbed and LHX1 expression is observed. Does this perturbation lead to a significant difference in LHX1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":613
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SKAP1 expression is observed. Does this perturbation lead to a significant difference in SKAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which FEV is perturbed and SKAP1 expression is observed. Does this perturbation lead to a significant difference in SKAP1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":713
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of RIMBP3C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CLDN6, does the expression profile of RIMBP3C indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3287
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Determine whether AC034228.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HNF4A is perturbed and the expression of AC034228.4 is measured. Determine whether AC034228.4 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4296
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ADD3. Does perturbing C19orf26 lead to a significant change in ADD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb C19orf26 and examine the expression of ADD3. Does perturbing C19orf26 lead to a significant change in ADD3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2901
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and PHACTR1 expression is quantified. Does this perturbation result in a significant change in PHACTR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, IGDCC3 is perturbed and PHACTR1 expression is quantified. Does this perturbation result in a significant change in PHACTR1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4382
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and PROX1 expression is measured. Determine whether PROX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and PROX1 expression is measured. Determine whether PROX1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4059
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CTD-3131K8.3 expression is observed. Does this perturbation lead to a significant difference in CTD-3131K8.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which MAP7D1 is perturbed and CTD-3131K8.3 expression is observed. Does this perturbation lead to a significant difference in CTD-3131K8.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2753
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb NCL and monitor NBR1 expression. Decide whether this perturbation leads to a significant alteration in NBR1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4888
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and MSRB1 expression is quantified. Does this perturbation result in a significant change in MSRB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, TP73 is perturbed and MSRB1 expression is quantified. Does this perturbation result in a significant change in MSRB1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2652
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of CTB-49A3.5. Does perturbing SAMD1 lead to a significant change in CTB-49A3.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SAMD1 and examine the expression of CTB-49A3.5. Does perturbing SAMD1 lead to a significant change in CTB-49A3.5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3391
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, BPGM is perturbed and the expression of TM4SF1-AS1 is measured. Does this perturbation cause a significant change in TM4SF1-AS1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3750
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of GIPR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of NIT1, does the expression profile of GIPR indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5357
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of CPVL. Does this perturbation cause a significant change in CPVL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to BCL2L11 and then measure expression of CPVL. Does this perturbation cause a significant change in CPVL expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4934
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of EWSAT1. Does perturbing ATL1 lead to a significant change in EWSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ATL1 and examine the expression of EWSAT1. Does perturbing ATL1 lead to a significant change in EWSAT1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5311
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ATP10D. Does this perturbation cause a significant change in ATP10D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to C19orf26 and then measure expression of ATP10D. Does this perturbation cause a significant change in ATP10D expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2924
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is quantified. Does this perturbation result in a significant change in RP11-497G19.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, COL2A1 is perturbed and RP11-497G19.7 expression is quantified. Does this perturbation result in a significant change in RP11-497G19.7 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1252
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of KIF2C is associated with a significant change in TRIM22 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4595
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN12 is perturbed and the expression of NKG7 is measured. Determine whether NKG7 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2596
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CKS1B and monitor ZEB2 expression. Decide whether this perturbation leads to a significant alteration in ZEB2 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3208
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Determine whether FILIP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, MAP2K3 is perturbed and the expression of FILIP1L is measured. Determine whether FILIP1L shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2266
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Determine whether KCNQ1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SPI1 is perturbed and the expression of KCNQ1-AS1 is measured. Determine whether KCNQ1-AS1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5116
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and NPW expression is observed. Does this perturbation lead to a significant difference in NPW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HK2 is perturbed and NPW expression is observed. Does this perturbation lead to a significant difference in NPW expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6043
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of C1orf141. Does this perturbation cause a significant change in C1orf141 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K3 and then measure expression of C1orf141. Does this perturbation cause a significant change in C1orf141 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2334
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CTD-3131K8.3. Does perturbing MAP7D1 lead to a significant change in CTD-3131K8.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of CTD-3131K8.3. Does perturbing MAP7D1 lead to a significant change in CTD-3131K8.3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2751
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TGFBR2 is associated with a significant change in BST2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5455
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ARID1A and monitor TXNIP expression. Decide whether this perturbation leads to a significant alteration in TXNIP expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4698
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of IGFL2. Does this perturbation cause a significant change in IGFL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TGFBR2 and then measure expression of IGFL2. Does this perturbation cause a significant change in IGFL2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5494
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM118A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TP73 is associated with a significant change in FAM118A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2665
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in HOGA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of MAPK1 is associated with a significant change in HOGA1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2865
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ANXA2R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of HOXA13, does the expression profile of ANXA2R indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5877
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in MTURN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of RHOXF2BB is associated with a significant change in MTURN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1885
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of PPP4R4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of KIF2C, does the expression profile of PPP4R4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4617
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb MEIS1 and monitor TUBB2B expression. Decide whether this perturbation leads to a significant alteration in TUBB2B expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":438
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ZNF85 expression is measured. Determine whether ZNF85 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, GLB1L2 is perturbed and ZNF85 expression is measured. Determine whether ZNF85 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":519
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor AK8 expression. Decide whether this perturbation leads to a significant alteration in AK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb IGDCC3 and monitor AK8 expression. Decide whether this perturbation leads to a significant alteration in AK8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4398
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of NUCB2. Does this perturbation cause a significant change in NUCB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to HOXC13 and then measure expression of NUCB2. Does this perturbation cause a significant change in NUCB2 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3134
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of NUDC. Does perturbing CNN1 lead to a significant change in NUDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CNN1 and examine the expression of NUDC. Does perturbing CNN1 lead to a significant change in NUDC expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2151
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RIT1. Does this perturbation cause a significant change in RIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NCL and then measure expression of RIT1. Does this perturbation cause a significant change in RIT1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4914
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in RETN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of PTPN1 is associated with a significant change in RETN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2455
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and DYNLT3 expression is measured. Determine whether DYNLT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TP73 is perturbed and DYNLT3 expression is measured. Determine whether DYNLT3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2679
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and CCNG2 expression is measured. Determine whether CCNG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SGK1 is perturbed and CCNG2 expression is measured. Determine whether CCNG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4069
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HHEX expression is quantified. Does this perturbation result in a significant change in HHEX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SAMD1 is perturbed and HHEX expression is quantified. Does this perturbation result in a significant change in HHEX expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3382
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BCL2L11 is perturbed and RP3-467K16.2 expression is measured. Determine whether RP3-467K16.2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4959
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLA2G1B. Does this perturbation cause a significant change in PLA2G1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CBL and then measure expression of PLA2G1B. Does this perturbation cause a significant change in PLA2G1B expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":754
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor IL20 expression. Decide whether this perturbation leads to a significant alteration in IL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb BPGM and monitor IL20 expression. Decide whether this perturbation leads to a significant alteration in IL20 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3768
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-128B16.3 expression is measured. Determine whether RP11-128B16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, AHR is perturbed and RP11-128B16.3 expression is measured. Determine whether RP11-128B16.3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1799
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and AREG expression is observed. Does this perturbation lead to a significant difference in AREG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which TBX2 is perturbed and AREG expression is observed. Does this perturbation lead to a significant difference in AREG expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2503
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-510J16.5. Does this perturbation cause a significant change in RP11-510J16.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of RP11-510J16.5. Does this perturbation cause a significant change in RP11-510J16.5 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1064
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LINC01562. Does perturbing ZBTB25 lead to a significant change in LINC01562 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB25 and examine the expression of LINC01562. Does perturbing ZBTB25 lead to a significant change in LINC01562 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1311
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CARMN. Does perturbing CLDN6 lead to a significant change in CARMN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CLDN6 and examine the expression of CARMN. Does perturbing CLDN6 lead to a significant change in CARMN expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3271
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, POU3F2 is perturbed and BTG2 expression is measured. Determine whether BTG2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2049
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of C1orf228. Does perturbing RREB1 lead to a significant change in C1orf228 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of C1orf228. Does perturbing RREB1 lead to a significant change in C1orf228 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1111
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and CHST15 expression is measured. Determine whether CHST15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, TBX2 is perturbed and CHST15 expression is measured. Determine whether CHST15 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2499
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which ZBTB25 is perturbed and LST1 expression is observed. Does this perturbation lead to a significant difference in LST1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1263
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ACTC1. Does perturbing NIT1 lead to a significant change in ACTC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb NIT1 and examine the expression of ACTC1. Does perturbing NIT1 lead to a significant change in ACTC1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5371
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor RBM5-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb CEBPE and monitor RBM5-AS1 expression. Decide whether this perturbation leads to a significant alteration in RBM5-AS1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":168
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CD59. Does this perturbation cause a significant change in CD59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CDKN1A and then measure expression of CD59. Does this perturbation cause a significant change in CD59 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2374
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, OSR2 is perturbed and the expression of SKAP2 is measured. Does this perturbation cause a significant change in SKAP2 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5040
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of TRAPPC3L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CDKN1C, does the expression profile of TRAPPC3L indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6257
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and TUBB3 expression is quantified. Does this perturbation result in a significant change in TUBB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ZBTB1 is perturbed and TUBB3 expression is quantified. Does this perturbation result in a significant change in TUBB3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3592
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MYOZ3 expression is quantified. Does this perturbation result in a significant change in MYOZ3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, LYL1 is perturbed and MYOZ3 expression is quantified. Does this perturbation result in a significant change in MYOZ3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3942
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor PGA4 expression. Decide whether this perturbation leads to a significant alteration in PGA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor PGA4 expression. Decide whether this perturbation leads to a significant alteration in PGA4 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6038
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of HIST1H3H. Does this perturbation cause a significant change in HIST1H3H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to NIT1 and then measure expression of HIST1H3H. Does this perturbation cause a significant change in HIST1H3H expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5334
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01420 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CDKN1B is associated with a significant change in LINC01420 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5425
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and KCNH2 expression is measured. Determine whether KCNH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL1A1 is perturbed and KCNH2 expression is measured. Determine whether KCNH2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3449
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PRTG is perturbed and CISH expression is observed. Does this perturbation lead to a significant difference in CISH expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3603
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of HIST1H4H. Does perturbing KMT2A lead to a significant change in HIST1H4H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KMT2A and examine the expression of HIST1H4H. Does perturbing KMT2A lead to a significant change in HIST1H4H expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4341
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of RP1-102K2.6. Does perturbing LHX1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb LHX1 and examine the expression of RP1-102K2.6. Does perturbing LHX1 lead to a significant change in RP1-102K2.6 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1011
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of SOX5. Does perturbing TBX2 lead to a significant change in SOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of SOX5. Does perturbing TBX2 lead to a significant change in SOX5 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2471
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to MAP4K5 and then measure expression of ARHGDIB. Does this perturbation cause a significant change in ARHGDIB expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1334
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of HERPUD1. Does perturbing SNAI1 lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb SNAI1 and examine the expression of HERPUD1. Does perturbing SNAI1 lead to a significant change in HERPUD1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5821
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of ELMSAN1 is associated with a significant change in HEMGN expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":255
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in RP11-662J14.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of CEBPB is associated with a significant change in RP11-662J14.2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5245
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, ETS2 is perturbed and the expression of TYROBP is measured. Determine whether TYROBP shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":796
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of SERPINF1. Does perturbing RREB1 lead to a significant change in SERPINF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb RREB1 and examine the expression of SERPINF1. Does perturbing RREB1 lead to a significant change in SERPINF1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1081
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CYP2C18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TBX3 is associated with a significant change in CYP2C18 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":935
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Determine whether HHEX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, SAMD1 is perturbed and the expression of HHEX is measured. Determine whether HHEX shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3386
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RP11-320G24.1 expression is observed. Does this perturbation lead to a significant difference in RP11-320G24.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RP11-320G24.1 expression is observed. Does this perturbation lead to a significant difference in RP11-320G24.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5063
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Determine whether C6orf1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, RHOXF2BB is perturbed and the expression of C6orf1 is measured. Determine whether C6orf1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1876
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of LRRC36. Does perturbing FOXA1 lead to a significant change in LRRC36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb FOXA1 and examine the expression of LRRC36. Does perturbing FOXA1 lead to a significant change in LRRC36 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":331
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SLC6A9, does the expression profile of RCSD1 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1447
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor TMEM35 expression. Decide whether this perturbation leads to a significant alteration in TMEM35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb ZC3HAV1 and monitor TMEM35 expression. Decide whether this perturbation leads to a significant alteration in TMEM35 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5018
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor AMPH expression. Decide whether this perturbation leads to a significant alteration in AMPH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb PRDM1 and monitor AMPH expression. Decide whether this perturbation leads to a significant alteration in AMPH expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6018
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of LEFTY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of BCL2L11, does the expression profile of LEFTY2 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4947
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb TBX2 and monitor MFGE8 expression. Decide whether this perturbation leads to a significant alteration in MFGE8 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2488
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is measured. Determine whether RP11-259K5.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, COL2A1 is perturbed and RP11-259K5.1 expression is measured. Determine whether RP11-259K5.1 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1249
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Determine whether VASH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FOXA3 is perturbed and the expression of VASH1 is measured. Determine whether VASH1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3356
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Does this perturbation cause a significant change in SOX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, CDKN1A is perturbed and the expression of SOX4 is measured. Does this perturbation cause a significant change in SOX4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2350
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, CSRNP1 is perturbed and the expression of PRKCB is measured. Determine whether PRKCB shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4626
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ETS2 is perturbed and CD52 expression is quantified. Does this perturbation result in a significant change in CD52 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":802
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, FOXF1 is perturbed and the expression of FOXF1 is measured. Does this perturbation cause a significant change in FOXF1 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3490
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and SH3BGRL expression is observed. Does this perturbation lead to a significant difference in SH3BGRL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which BCORL1 is perturbed and SH3BGRL expression is observed. Does this perturbation lead to a significant difference in SH3BGRL expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":393
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PTRF. Does this perturbation cause a significant change in PTRF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to SLC4A1 and then measure expression of PTRF. Does this perturbation cause a significant change in PTRF expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1034
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Determine whether SLC20A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PTPN1 is perturbed and the expression of SLC20A1 is measured. Determine whether SLC20A1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2406
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Determine whether RP3-525N10.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HOXA13 is perturbed and the expression of RP3-525N10.2 is measured. Determine whether RP3-525N10.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5896
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SAT1 expression is quantified. Does this perturbation result in a significant change in SAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, FOXO4 is perturbed and SAT1 expression is quantified. Does this perturbation result in a significant change in SAT1 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1802
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, TBX2 is perturbed and the expression of FEV is measured. Determine whether FEV shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2466
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ABCB11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of CBFA2T3, does the expression profile of ABCB11 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1667
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and AC078941.1 expression is observed. Does this perturbation lead to a significant difference in AC078941.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which S1PR2 is perturbed and AC078941.1 expression is observed. Does this perturbation lead to a significant difference in AC078941.1 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2013
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and SLC43A2 expression is measured. Determine whether SLC43A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, MIDN is perturbed and SLC43A2 expression is measured. Determine whether SLC43A2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1539
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in RP11-714G18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FOXO4 is associated with a significant change in RP11-714G18.1 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1855
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-128B16.3 expression is observed. Does this perturbation lead to a significant difference in RP11-128B16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which AHR is perturbed and RP11-128B16.3 expression is observed. Does this perturbation lead to a significant difference in RP11-128B16.3 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1793
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CYP3A5 expression is measured. Determine whether CYP3A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SET is perturbed and CYP3A5 expression is measured. Determine whether CYP3A5 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":869
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to PTPN13 and then measure expression of FCER1G. Does this perturbation cause a significant change in FCER1G expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5644
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of FEZ1. Does perturbing ZBTB1 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZBTB1 and examine the expression of FEZ1. Does perturbing ZBTB1 lead to a significant change in FEZ1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3561
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CDC20. Does perturbing CDKN1B lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CDKN1B and examine the expression of CDC20. Does perturbing CDKN1B lead to a significant change in CDC20 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5401
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, EGR1 is perturbed and the expression of CD52 is measured. Does this perturbation cause a significant change in CD52 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6180
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of SLC4A1 is associated with a significant change in PHLDA2 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1025
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FAM83A expression is observed. Does this perturbation lead to a significant difference in FAM83A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which PTPN13 is perturbed and FAM83A expression is observed. Does this perturbation lead to a significant difference in FAM83A expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5623
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CNNM4 is perturbed and PHLDA2 expression is measured. Determine whether PHLDA2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4769
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and LMNA expression is observed. Does this perturbation lead to a significant difference in LMNA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which HES7 is perturbed and LMNA expression is observed. Does this perturbation lead to a significant difference in LMNA expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1683
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of SET, does the expression profile of ZNF467 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":877
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in GIPR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in GIPR expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5355
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Determine whether RAB5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, FEV is perturbed and the expression of RAB5B is measured. Determine whether RAB5B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":686
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Does this perturbation cause a significant change in TFAP2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP4K3 is perturbed and the expression of TFAP2A is measured. Does this perturbation cause a significant change in TFAP2A expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2310
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, BPGM is perturbed and CD24 expression is measured. Determine whether CD24 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3739
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Does this perturbation cause a significant change in ASIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, MAP2K3 is perturbed and the expression of ASIC4 is measured. Does this perturbation cause a significant change in ASIC4 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2240
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and STAC3 expression is measured. Determine whether STAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, ELMSAN1 is perturbed and STAC3 expression is measured. Determine whether STAC3 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":279
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of PRSS57. Does perturbing KIAA1804 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb KIAA1804 and examine the expression of PRSS57. Does perturbing KIAA1804 lead to a significant change in PRSS57 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4161
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, UBASH3B is perturbed and the expression of UBASH3B is measured. Determine whether UBASH3B shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1406
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, CDKN1C is perturbed and ALAS2 expression is measured. Determine whether ALAS2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6239
  },
  {
    "question":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor RP11-452C8.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-452C8.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a functional genomics specialist. In K562 cells, we perturb SGK1 and monitor RP11-452C8.1 expression. Decide whether this perturbation leads to a significant alteration in RP11-452C8.1 expression. Answer only in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4078
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Determine whether LMNA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, HES7 is perturbed and the expression of LMNA is measured. Determine whether LMNA shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1686
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of TSC22D1 is associated with a significant change in RP1-34B20.21 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, SLC6A9 is perturbed and CCR10 expression is measured. Determine whether CCR10 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1489
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in C19orf38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of UBASH3A is associated with a significant change in C19orf38 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4845
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which OSR2 is perturbed and RNF213 expression is observed. Does this perturbation lead to a significant difference in RNF213 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5023
  },
  {
    "question":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ZNF85 expression is observed. Does this perturbation lead to a significant difference in ZNF85 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in regulatory genomics. Consider data from K562 cells in which GLB1L2 is perturbed and ZNF85 expression is observed. Does this perturbation lead to a significant difference in ZNF85 expression relative to control conditions? Answer strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":513
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is quantified. Does this perturbation result in a significant change in RP11-563J2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, ARRDC3 is perturbed and RP11-563J2.3 expression is quantified. Does this perturbation result in a significant change in RP11-563J2.3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3812
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in TOR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of NIT1 is associated with a significant change in TOR3A expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5345
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of COL1A1. Does perturbing OSR2 lead to a significant change in COL1A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb OSR2 and examine the expression of COL1A1. Does perturbing OSR2 lead to a significant change in COL1A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5051
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C3orf72 is perturbed and MFSD2A expression is measured. Determine whether MFSD2A exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3879
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of SLC8A1. Does perturbing TMSB4X lead to a significant change in SLC8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TMSB4X and examine the expression of SLC8A1. Does perturbing TMSB4X lead to a significant change in SLC8A1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4551
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to TSC22D1 and then measure expression of RP1-34B20.21. Does this perturbation cause a significant change in RP1-34B20.21 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Determine whether TACC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, PRDM1 is perturbed and the expression of TACC1 is measured. Determine whether TACC1 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6006
  },
  {
    "question":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Does this perturbation cause a significant change in RP11-362K14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert in single-cell biology and functional genomics. In K562 cells, KIAA1804 is perturbed and the expression of RP11-362K14.7 is measured. Does this perturbation cause a significant change in RP11-362K14.7 expression? Answer strictly in the format 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4180
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA5 expression is quantified. Does this perturbation result in a significant change in ANXA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, MAPK1 is perturbed and ANXA5 expression is quantified. Does this perturbation result in a significant change in ANXA5 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2852
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and LINC01338 expression is quantified. Does this perturbation result in a significant change in LINC01338 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, OSR2 is perturbed and LINC01338 expression is quantified. Does this perturbation result in a significant change in LINC01338 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5072
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of PGA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PRDM1, does the expression profile of PGA4 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6037
  },
  {
    "question":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are assisting with the interpretation of perturbation-based expression data. In K562 cells, SPI1 is perturbed and ZMAT3 expression is quantified. Does this perturbation result in a significant change in ZMAT3 expression compared with control cells? Respond exactly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":5132
  },
  {
    "question":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a specialist in gene perturbation experiments. In K562 cells, we introduce a perturbation to CSRNP1 and then measure expression of LGALS1. Does this perturbation cause a significant change in LGALS1 expression? Reply only in the form 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4634
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of FAM101B. Does perturbing ZNF318 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb ZNF318 and examine the expression of FAM101B. Does perturbing ZNF318 lead to a significant change in FAM101B expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":1141
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of HOXB9 is associated with a significant change in FABP5 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":3065
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of SPTAN1. Does perturbing CELF2 lead to a significant change in SPTAN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb CELF2 and examine the expression of SPTAN1. Does perturbing CELF2 lead to a significant change in SPTAN1 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2161
  },
  {
    "question":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ZNF610 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are an expert analyst of perturbation datasets. For K562 cells subjected to perturbation of PTPN1, does the expression profile of ZNF610 indicate a significant change relative to control conditions? Reply strictly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2437
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in PTPRS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of FEV is associated with a significant change in PTPRS expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":665
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of EGR1 is associated with a significant change in BLVRB expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":6175
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TNNI3. Does perturbing MAP7D1 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb MAP7D1 and examine the expression of TNNI3. Does perturbing MAP7D1 lead to a significant change in TNNI3 expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2701
  },
  {
    "question":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene regulation studies. For experiments performed in K562 cells, C19orf26 is perturbed and SAT2 expression is measured. Determine whether SAT2 exhibits a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2889
  },
  {
    "question":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in LGALS12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are an expert in gene expression analysis. For K562 cells, assess whether perturbation of DUSP9 is associated with a significant change in LGALS12 expression compared with unperturbed controls. Answer strictly as 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":185
  },
  {
    "question":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of FEV. Does perturbing TBX2 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"Yes",
    "question_new":"You are a domain expert in functional genomics. For experiments carried out in K562 cells, we perturb TBX2 and examine the expression of FEV. Does perturbing TBX2 lead to a significant change in FEV expression? Reply only with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":2461
  },
  {
    "question":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Determine whether RP11-285F7.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "answer":"No",
    "question_new":"You are a genomics expert evaluating perturbation experiments. In K562 cells, NCL is perturbed and the expression of RP11-285F7.2 is measured. Determine whether RP11-285F7.2 shows a significant expression change under this perturbation. Respond exactly with 'Final Answer: Yes' or 'Final Answer: No'.",
    "_id":4906
  }
]